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Idiopathic Congenital Cervical Megaesophagus in a Kid 儿童特发性先天性颈大食管
Q4 Veterinary Pub Date : 2021-04-21 DOI: 10.30500/IVSA.2021.271465.1247
M. Ahmadnejad, G. Jalilzadeh-Amin, S. Hashemi-Asl
Megaesophagus is atony and dilatation of the esophagus that is usually congenitally but acquired cases also happen. Salivation, regurgitation, aspiration pneumonia, and esophagitis are complications of the megaesophagus. Megaesophagus has been reported in various animals including horses, cows, buffaloes, goats, sheep, dogs, and cats but the occurrence is rare in ruminants. The exact etiology of the megaesophagus remains unknown. A two-day-old kid from a goatherd was referred to veterinary education and teaching hospital who regurgitate after milk feeding and sometimes cough. An Enlargement was felt under the throat after milk feeding. Two similar cases in this herd had died with these symptoms in the past month. All vital signs and complete blood cell count of the animal were normal. Lateral plain radiographs and contrast radiographs with barium contrast were performed for further examination. Radiographic findings confirmed the congenital cervical megaesophagus. Esophageal massage to the down direction and the forelimb raising after eating a small amount of milk was also recommended for this animal as a treatment protocol. It was recommended that the bucks should be culled to control the possible genetic origin. In our follow-up after a week, the kid was alive, but dead in the second week. This report presents the descriptions of clinical and radiographical findings of a congenital cervical megaesophagus in a kid. The complications can be relatively controlled with special care, but it is unlikely that the animal can be kept alive for long periods.
巨食管是一种先天性食管松弛和扩张,但也会发生后天性病例。流涎、反流、吸入性肺炎和食管炎是大食管的并发症。据报道,包括马、牛、水牛、山羊、绵羊、狗和猫在内的各种动物都患有巨食道,但反刍动物中这种情况很少见。巨食管的确切病因尚不清楚。一个来自牧羊场的两天大的孩子被转诊到兽医教育教学医院,他在喂完奶后会反胃,有时还会咳嗽。喂完奶后,喉咙感觉到肿大。在过去的一个月里,这群动物中有两个类似的病例死于这些症状。动物的所有生命体征和全血细胞计数均正常。进行侧位平片和钡造影造影片进一步检查。影像学检查证实了先天性颈部巨食道。作为治疗方案,该动物还建议向下按摩食道,并在食用少量牛奶后抬起前肢。有人建议应该扑杀雄鹿,以控制可能的遗传来源。在一周后的随访中,孩子还活着,但在第二周就死了。本报告介绍了一例儿童先天性颈部巨食管的临床和放射学表现。并发症可以通过特殊护理相对控制,但动物不太可能长时间存活。
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引用次数: 0
Lameness and Radial Nerve Neuropathy Caused By Chondroma Tumor in a Male Dog 雄犬软骨瘤引起的跛行和桡神经病变
Q4 Veterinary Pub Date : 2021-02-24 DOI: 10.30500/IVSA.2021.263474.1240
Hamed Masoudi, R. Mazaheri-Khameneh
A 5-year-old mongrel male dog with severe left forelimb lameness was referred to the veterinary clinic of Urmia University. On initial physical examination, vital signs were normal. However, a firm swelling with a history of one year progressive increasing in size was observed on the caudolateral aspect of the left shoulder. Pedal reflex was negative. On radiographic examination, a large mass with abnormal radiodensity was seen in the caudal humerus. Hypodermic needle aspiration specimen were unremarkable except large number of normal blood cells. Under general anesthesia, the tumoral mass was surgically removed via a caudolateral approach to the humerus. Pathological assessments corroborated the lobular pattern with the presence of tumor cells similar to normal chondrocytes in an amorphous, basophilic matrix that confirmed the chondroma tumor. In the postoperative follow-up, normal nerve function was returned and lameness was disappeared. Chondroma tumors should be considered in the differential diagnosis of dogs with persistent lameness and neuropathies.
一只患有严重左前肢跛脚的5岁杂种公犬被送往乌尔米亚大学兽医诊所。经初步身体检查,生命体征正常。然而,在左肩后侧观察到一个有一年逐渐增大病史的牢固肿胀。踏板反射为阴性。在影像学检查中,肱骨尾部可见一个具有异常放射密度的大肿块。皮下针吸标本除大量正常血细胞外,无明显异常。在全身麻醉下,肿瘤块通过手术切除,经肱骨烧灼侧入路。病理学评估证实了小叶模式,在无定形嗜碱性基质中存在与正常软骨细胞相似的肿瘤细胞,证实了软骨瘤。在术后随访中,神经功能恢复正常,跛行消失。在鉴别诊断患有持续性跛行和神经病变的狗时,应考虑软骨瘤肿瘤。
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引用次数: 0
Malignant (Anaplastic) Amelanotic/Hypomelanotic Melanoma in a Kurdish Gelding 库尔德骟马的恶性(间变性)无色素/低黑色素黑色素瘤
Q4 Veterinary Pub Date : 2021-02-24 DOI: 10.30500/IVSA.2021.259636.1234
Hamed Masoudi, S. Azizi, A. Sadi
We report an 11-year-old Kurdish gelding with an anaplastic malignant melanoma arising from his right lateral of the neck, which developed over 6 weeks. A ~10 cm in diameter, firm, and non-ulcerated nodular subcutaneous mass located at the middle and proximal of the left side of the neck was detected in a physical examination. No evidence of local extent or metastasis was detected. Complete surgical excision was performed under general anesthesia. Gross morphology and histopathological examination of the mass confirmed an anaplastic malignant melanoma, in which the major part of the mass has little or no pigmentation. The gelding was euthanized due to tumor regrowth. The heterogeneity in pigmentation of equine melanocytic tumors can make diagnosis difficult in punch biopsy specimens. Anaplastic malignant melanoma is most often a very aggressive neoplasm and surgical excision was not effective in this case.
我们报告了一个11岁的库尔德骟马与间变性恶性黑色素瘤产生于他的右颈外侧,发展超过6周。体格检查发现一直径约10cm,坚固,未溃烂的结节状皮下肿块,位于颈部左侧中部和近端。未发现局部范围或转移的证据。在全身麻醉下完成手术切除。肿块的大体形态和组织病理学检查证实为间变性恶性黑色素瘤,肿块的主要部分很少或没有色素沉着。这匹骟马因肿瘤再生而被安乐死。马黑色素细胞肿瘤色素沉着的异质性使其在穿刺活检标本中诊断困难。间变性恶性黑色素瘤通常是一种非常具有侵袭性的肿瘤,手术切除在这种情况下是无效的。
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引用次数: 0
Evaluation of Electrospun of Polyvinyl Alcohol Nanofiber Containing Eucalyptus globules Extract on the Healing of Experimental Achilles Tendon Injury in Rat 桉树微球提取物聚乙烯醇纳米纤维静电纺丝对实验性大鼠跟腱损伤愈合的影响
Q4 Veterinary Pub Date : 2021-02-20 DOI: 10.30500/IVSA.2021.262669.1237
H. Moslemi, Seyed Mohammad Ali Sadat-Hosseini, M. Nourbakhsh, S. G. Khaligh
Injury and degeneration of tendons can be highly debilitating and can result in substantial pain, disability, and health-care costs. Nano-sized fibers have a much wider surface area than conventionally produced fibers, which can hold composite materials more compactly and thus provide greater mechanical capabilities. In this study, the injured tendon was treated by electrospun PVA mats containing Eucalyptus extract and histopathological results of healing were evaluated. 45 male Wistar rats were used in this study. For this study, 45 male Wistar rats were prepared and a partial thickness tenotomy was created on right hindlimbs. All rats were divided into three groups (n = 15) and three sub-groups (n = 5) including, Eucalyptus extract-loaded nanofibers, PVA nanofiber, and without any treatment as a control group. Histological samples were taken on days 14, 28, and 42. The histological analysis on day 14 indicated no significant difference was observed between all groups (p > 0.05). While on days 28 and 42 post-rupture indicated a higher regenerating activity and capacity in the Eucalyptus extract-loaded nanofibers than PVA nanofiber and control groups (p ≤ 0.05). In summary, these results suggest that the Eucalyptus extract-loaded nanofibers mats promoted the healing process of damaged Achilles tendon in rats.
肌腱的损伤和退化会使人非常虚弱,并可能导致巨大的疼痛、残疾和医疗费用。纳米纤维比传统生产的纤维具有更宽的表面积,可以更紧凑地保持复合材料,从而提供更大的机械性能。在本研究中,用含有桉树提取物的电纺PVA垫治疗受伤的肌腱,并评估愈合的组织病理学结果。本研究选用雄性Wistar大鼠45只。在本研究中,制备了45只雄性Wistar大鼠,并在右后肢上进行了部分厚度的肌腱切开术。将所有大鼠分为三组(n=15)和三个子组(n=5),包括桉树提取物负载的纳米纤维、PVA纳米纤维,并作为对照组不进行任何治疗。在第14、28和42天采集组织学样本。第14天的组织学分析表明,所有组之间没有观察到显著差异(p>0.05)。而在破裂后的第28和42天则表明,负载桉树提取物的纳米纤维比PVA纳米纤维和对照组具有更高的再生活性和能力(p≤0.05)。总之,这些结果表明,桉树提取物负载的纳米纤维垫促进了大鼠跟腱损伤的愈合过程。
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引用次数: 0
The Effects of Honey, Curcuma, Ginger, Nigella sativa and Their Mixture on the Radial Bone Defect Repair in Rat Model: Histological and Biomechanical Study 蜂蜜、姜黄、生姜、Nigella sativa及其混合物对大鼠桡骨缺损修复作用的组织学和生物力学研究
Q4 Veterinary Pub Date : 2021-02-20 DOI: 10.30500/IVSA.2021.262771.1238
Mohammad Mahmoudi-Fard, S. Dehghani, B. Nikahval
Honey, Curcuma, Ginger, and Nigella sativa are known for their antioxidant, immune stimulation properties, and wound healing effects. This study was conducted to determine the effect of these compounds and their mixture on the bone healing of the radial bone defect model in rats. 110 radial bone defects in 55 healthy male rats were randomly divided into 11 groups (10 rats per group). Group 1-5 received honey, Curcuma, Ginger, and Nigella sativa orally by gavage, and group 6-10 received the same materials locally by rubbing them on the sutured skin. The bone repair effects of these materials were evaluated by histopathology and biomechanical examinations. Using honey, Curcuma, Ginger, and Nigella sativa exhibited a beneficial effect to promote bone healing in this study. The biomechanical and histopathology evaluation showed that the honey (oral), a mixture of honey and Curcuma (oral), and a mixture of honey and Nigella sativa (topical) groups, exhibited significantly better result at 52nd postoperative day compared to the other groups as well as the control group.
蜂蜜、姜黄、生姜和Nigella sativa以其抗氧化、免疫刺激特性和伤口愈合效果而闻名。本研究旨在确定这些化合物及其混合物对大鼠桡骨骨缺损模型骨愈合的影响。55只健康雄性大鼠的110个桡骨骨缺损被随机分为11组(每组10只)。第1-5组通过灌胃方式口服蜂蜜、姜黄、生姜和Nigella sativa,第6-10组通过在缝合的皮肤上摩擦局部接受相同的材料。通过组织病理学和生物力学检查评价这些材料的骨修复效果。在本研究中,使用蜂蜜、姜黄、生姜和奈杰尔拉对促进骨愈合表现出有益的效果。生物力学和组织病理学评估显示,与其他组和对照组相比,蜂蜜(口服)、蜂蜜和姜黄的混合物(口服)以及蜂蜜和奈杰尔拉的混合物(外用)组在术后第52天表现出明显更好的结果。
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引用次数: 0
The Ameliorative Impacts of Berberine on Testicular Ischemia/reperfusion Injury in Rats: An Experimental Study 小檗碱对大鼠睾丸缺血再灌注损伤改善作用的实验研究
Q4 Veterinary Pub Date : 2021-02-15 DOI: 10.30500/IVSA.2021.263095.1239
Masoumeh Moradi-Ozarlou, M. Ashrafizadeh, S. Javanmardi
Ischemia/reperfusion is one of the emergency cases that frequently occurs in testis. This pathologic event is one of the reasons for infertility in men. Inflammation and oxidative stress induce ischemia/reperfusion injury in testis. Consequently, agents possessing antioxidant activity are applied in the treatment of testicular ischemia/reperfusion. In the present study, the effect of berberine administration in the treatment of testicular ischemia/reperfusion injury is investigated. In this experiment, 24 Wistar rats were randomly divided into four groups (n=6): Sham group (receiving normal saline 0.9%), control group (ischemia/reperfusion), treatment I group (ischemia/reperfusion group receiving 50 mg/kg berberine), and treatment II group (ischemia/reperfusion receiving 100 mg/kg berberine). All injections were performed through the intraperitoneal route. Histopathological findings demonstrated that in the Sham group, testis has normal structure and normal spermatogenesis occurs. In the ischemia group, severe hyperemia, coagulative necrosis, and interstitial edema are observed and spermatogenesis has severe damage. In treatment I group (50 mg/kg of berberine), moderate interstitial edema, hyperemia, and coagulative necrosis are observed. Besides, spermatogenesis has moderate damage. In group treated with a high dose of berberine (100 mg/kg), all damages are mild. This experiment reveals that berberine exerts its protective impact in a dose-dependent manner so that the highest protective impact is observed in the group treated with 100 mg/kg of berberine. With respect to the major role of testicular ischemia in infertility and the results of the present study, berberine can be used as a valuable plant extract in the treatment of testicular ischemia and preventing its harmful impacts.
睾丸缺血/再灌注是睾丸常见的急症之一。这种病理事件是男性不育的原因之一。炎症和氧化应激诱导睾丸缺血/再灌注损伤。因此,具有抗氧化活性的药物被应用于睾丸缺血/再灌注的治疗。本研究探讨了黄连素对睾丸缺血再灌注损伤的治疗作用。在本实验中,24只Wistar大鼠随机分为四组(n=6):Sham组(接受0.9%生理盐水)、对照组(缺血/再灌注)、治疗I组(接受50mg/kg黄连素的缺血/再灌组)和治疗II组(接受100mg/kg黄连素)。所有注射均通过腹膜内途径进行。组织病理学结果表明,Sham组睾丸结构正常,精子发生正常。缺血组出现严重充血、凝固性坏死和间质水肿,精子发生受到严重损害。在治疗I组(50 mg/kg的黄连素)中,观察到中度间质水肿、充血和凝固性坏死。此外,精子发生也有中度损伤。高剂量黄连素组(100mg/kg),所有损伤均为轻度。该实验表明,黄连素以剂量依赖的方式发挥其保护作用,因此在用100mg/kg黄连素治疗的组中观察到最高的保护作用。关于睾丸缺血在不孕中的主要作用和本研究的结果,黄连素可作为一种有价值的植物提取物用于治疗睾丸缺血并预防其有害影响。
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引用次数: 1
Collagenase Induced Tendinitis in Forelimb Superficial Digital Flexor Tendon in Donkey (Equus asinus): Long Term Ultrasonographic and Biomechanical Assessments 胶原酶诱导的驴子(马)前臂指浅屈肌腱肌炎:长期超声和生物力学评估
Q4 Veterinary Pub Date : 2021-02-06 DOI: 10.30500/IVSA.2021.255849.1231
Mohammad-Hazhir Alaei, R. Mohammadi, S. Hashemi-Asl, S. Asri-Rezaei, M. Behfar, A. Tehrani
Injuries to tendons are among the most common injuries in competition horses and represent a significant cause of morbidity and mortality. The present study aimed at an eight -week period ultrasonographic and biomechanical assessments of collagenase induced tendinitis in forelimb superficial digital flexor tendon (SDFT) in donkeys. Four healthy male donkeys were used. 1000 U collagenase type I from Clostridium histolyticum was injected in the center of the SDFT guided by ultrasonography. Ultrasonographical images of the SDFT were recorded prior to injury and 8 weeks after confirmation of tendinitis on a weekly basis. Images were digitized and lesion area to cross-sectional tendon area ratio (LA/TA ratios) was measured. At the end of the study period, the animals underwent tenectomy and tendon samples were evaluated biomechanically. Collagenase induced tendinitis was confirmed ultrasonographically 10 days post-injection. The animals showed swelling and response to palpation, however, no lameness was found in animals within the study period. There were significant differences between the first and the fifth weeks in operated limbs ultrasonographically (p < 0.05). The eight-week period is sufficient to assess the effect of various modalities in tendon healing in the collagenase-induced model in the donkey. The development and expansion of collagenase induced tendinitis until week six after confirmation of tendinitis may disturb findings of the healing effect of various modalities in the tendon, in which tendinitis is still expanding and may mask the healing effect of the modalities used.
肌腱损伤是比赛马匹最常见的损伤之一,也是发病率和死亡率的重要原因。本研究旨在对胶原酶诱导的驴前肢指浅屈肌腱肌腱炎(SDFT)进行为期八周的超声和生物力学评估。使用了四头健康的公驴。在超声引导下在SDFT中心注射来自溶组织梭菌的1000U I型胶原酶。SDFT的超声图像在受伤前和肌腱炎确诊后8周每周记录一次。对图像进行数字化,并测量病变面积与肌腱横截面面积的比率(LA/TA比率)。在研究期结束时,动物接受了肌腱切除术,并对肌腱样本进行了生物力学评估。胶原酶诱导的肌腱炎在注射后10天经超声证实。动物出现肿胀和触诊反应,但在研究期内未发现动物跛脚。在第一周和第五周的超声检查中,手术肢体之间存在显著差异(p<0.05)。八周的时间足以评估胶原酶诱导的驴模型中各种方式对肌腱愈合的影响。胶原酶诱导的肌腱炎的发展和扩张直到肌腱炎确诊后的第六周,可能会干扰肌腱中各种模式的愈合效果的发现,其中肌腱炎仍在扩张,并可能掩盖所用模式的愈合作用。
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引用次数: 0
Intermuscular Lipoma in the Pelvic Limb of an Aged Shih Tzu-Terrier Dog 老年西施犬骨盆肢体肌肉间脂肪瘤的研究
Q4 Veterinary Pub Date : 2021-02-04 DOI: 10.30500/IVSA.2021.259320.1233
D. Kazemi, M. N. Gharamaleki
A ten and half year old spayed female shihtzu-terrier dog was presented with swollen mass in the right pelvic limb. The mass was first noticed by the owner three months prior to presentation but it had enlarged significantly during the past seven days before presentation resulting in pain and lameness. Clinical examination revealed the presence of a large fluctuant mass with soft tissue consistency in the caudal region of the right stifle joint with pain elicited during joint flexion. A well circumscribed large fatty tumour situated between the semimembranosus and semitendinosus muscles was encountered during surgical exploration of the affected area under general anesthesia which was completely removed. Diagnosis of intermuscular lipoma was confirmed based on clinical findings, gross appearance of the tumour and presence of mature adipocytes in histological sections. This report describes clinical signs, physical examination and diagnostic imaging findings along with surgical treatment of canine intermuscular lipoma, a rare form of lipoma and benign mesenchymal tumour of adipose tissue situated between muscle bellies which is not locally invasive and does not metastasize. To the best of our knowledge, this type of canine tumour has not been previously reported in Iran.
一只10岁半的雌性实足犬被切除了生殖器官,其右骨盆肢体出现肿胀肿块。肿块在出现前三个月首次被主人发现,但在出现前的过去七天里,肿块明显扩大,导致疼痛和跛行。临床检查显示,右膝关节尾部存在一个软组织一致的大的波动性肿块,在关节屈曲过程中引发疼痛。在全身麻醉下对受影响区域进行手术探查时,发现位于半膜肌和半腱肌之间的边界清晰的大型脂肪瘤,该肿瘤已完全切除。根据临床表现、肿瘤的大体外观和组织学切片中成熟脂肪细胞的存在,确认了肌间脂肪瘤的诊断。本报告描述了犬肌间脂肪瘤的临床症状、体格检查和诊断性影像学表现,以及手术治疗。肌间脂肪瘤是一种罕见的脂肪瘤,是位于肌肉腹部之间的脂肪组织的良性间充质肿瘤,没有局部侵袭性,也没有转移。据我们所知,这种类型的犬肿瘤以前在伊朗没有报道过。
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引用次数: 0
Evaluation of vertebral heart score and cardiac sphericity in apparently normal dogs 表面正常犬椎心评分和心球度的评价
Q4 Veterinary Pub Date : 2021-02-02 DOI: 10.30500/IVSA.2021.253846.1229
M. Bappah, azu Nuhu, N. Chom, M. Lawal, Abdullaziz Abdullahi Bada, S. Muhammad
AbstractObjectives- Evaluate the relationship between vertebral heart score and cardiac sphericity, and evaluate gender variation in both dimensions in apparently normal Nigeria indigenous dogs.Design- Experimental study Animals- Twelve (six males and six females) apparently normal Nigerian indigenous dogs were selected from dogs in Zaria, Nigeria.Procedures- Radiographic evaluations involved left lateral views of the thoracic region of the dogs. The vertebral heart size was measured as the sum of the long-axis and short-axis at its greatest diameter then compared with the vertebra bones starting at T4. Cardiac sphericity was obtained by computing the ratio of the long-axis to the short-axis. Results- The mean ± SD for vertebral heart score and cardiac sphericity index in apparently normal Nigerian indigenous dogs were 9.3 ± 0.44v and 0.77 ± 0.06 respectively. Pearson coefficient revealed a significant (P = 0.001) and very strong correlation (P = 0.81) between vertebral heart score and cardiac sphericity index in Nigerian indigenous dogs. There were no gender variations in both dimensions.Conclusions and Clinical Relevance- This study revealed the existence of a strong relationship between vertebral heart score and cardiac sphericity index in dogs in apparently normal Nigerian indigenous dogs, and both dimensions demonstrated no gender variation. Vertebral heart score and cardiac sphericity index in apparently normal Nigerian indigenous dogs are expressed as an ideal cardiac dimensions which are suggested to be a useful quantitative and objective parameters in the diagnosis of cardiac disorders in dogs.
摘要目的-评估明显正常的尼日利亚本土犬的脊椎心脏评分和心脏球形度之间的关系,并评估两个维度的性别差异。设计-实验研究动物-从尼日利亚扎里亚的狗中选择12只(6只雄性和6只雌性)明显正常的尼日利亚本土狗。程序-射线评估涉及狗胸部的左侧视图。将脊椎心脏尺寸测量为其最大直径处的长轴和短轴的总和,然后与T4开始的脊椎骨进行比较。通过计算长轴与短轴的比值来获得心脏球形度。结果-明显正常的尼日利亚本土犬的椎心评分和心球度指数的平均值±SD分别为9.3±0.44v和0.77±0.06。Pearson系数显示,尼日利亚本土犬的椎心评分和心球度指数之间存在显著(P=0.001)和非常强的相关性(P=0.81)。两个方面都没有性别差异。结论和临床相关性——这项研究表明,在明显正常的尼日利亚本土犬中,犬的椎心评分和心球度指数之间存在着密切的关系,并且这两个维度都没有性别差异。明显正常的尼日利亚本土犬的椎心评分和心球度指数被表示为理想的心脏尺寸,这被认为是诊断犬心脏疾病的有用的定量和客观参数。
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引用次数: 1
Comparison of Production of Pain and Oxidative Stress after Induction of Local Nerve Block or Use of NSAIDs Following Painful Dental Procedures in Dogs 犬疼痛牙科手术后局部神经阻滞或使用非甾体抗炎药后疼痛和氧化应激产生的比较
Q4 Veterinary Pub Date : 2021-01-25 DOI: 10.30500/IVSA.2021.252101.1228
A. Tavakoli, M. Tazik, A. Abbasi
Objective- The objective of the present study was to investigate the superiority of rostral maxillary nerve blocks using the combination of lidocaine and bupivacaine or pre-operative administration of meloxicam in controlling the pain following the surgery in dogs undergoing dental pulpotomy in the rostral maxilla. Animals- Twelve dogs with healthy teeth were included in this study.  Design- Under general anesthesia, each dog was randomly assigned to receive either rostral maxillary nerve block with the combination of lidocaine and bupivacaine (0.4 ml per site) (Group A) or intravenous meloxicam (0.2 mg/kg) (Group B) prior to pulpotomy. Procedures- Pulpotomy was performed in the right or left upper corner incisor teeth of each dog using a single technique. The score of pain was recorded using UMPS at 3, 5, and 24 hours after surgery and assessment of serum level of cortisol and indicators of oxidative stress including Total Antioxidant Capacity (TAC) and value of Malondialdehyde in hemolysis of red blood cells (MDA) prior to surgery and at 30 min, 3 and 24 hours post-operatively. Results- The highest score of pain was recorded at 5 hours after a pulpotomy, which was significantly higher in group B in comparison to group A (P = 0.026). Mean± SD level of cortisol was significantly higher in group B at 30 min, 1 and 3 hours after pulpotomy in dogs of the group B compared to group A (p 0.05) Mean ± SEM TAC values were significantly lower in group A compared to group B. (p < 0.05). However, Mean±SEM values of MDA were significantly higher in group A at different time intervals in comparison to group B. (p < 0.05).Conclusion and Clinical Relevance- It is concluded that rostral maxillary nerve block by using the combination of lidocaine and bupivacaine in painful dental procedures seems more effective than administration of meloxicam to control pain resulted from pulpotomy in dogs in early hours.
目的:本研究的目的是研究利多卡因和布比卡因联合使用或术前给药美洛昔康的上颌前神经阻滞在控制接受上颌前牙髓切断术的狗手术后疼痛方面的优越性。动物——本研究包括12只牙齿健康的狗。设计-在全身麻醉下,每只狗被随机分配在牙髓切断术前接受利多卡因和布比卡因组合的上颌前神经阻滞(每个部位0.4 ml)(A组)或静脉注射美洛昔康(0.2 mg/kg)(B组)。手术-使用单一技术对每只狗的右上角门牙或左上角门齿进行牙髓切除术。使用UMPS在手术后3、5和24小时记录疼痛评分,并评估血清皮质醇水平和氧化应激指标,包括手术前和手术后30分钟、3和24小时的总抗氧化能力(TAC)和丙二醛在红细胞溶血(MDA)中的值。结果-牙髓切开术后5小时疼痛评分最高,B组明显高于a组(P=0.026)。30分钟时,B组皮质醇平均±SD水平显著高于a组,与A组相比,B组狗在牙髓切断术后1和3小时的平均±SEM TAC值显著低于B组(p<0.05),与B组相比,A组在不同时间间隔的MDA平均值±SEM值显著更高。(p<0.05)。结论和临床相关性-研究表明,在疼痛的牙科手术中使用利多卡因和布比卡因联合应用上颌窦前神经阻滞似乎比使用美洛昔康更有效地控制狗牙髓炎引起的疼痛在凌晨。
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引用次数: 2
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Iranian Journal of Veterinary Surgery
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