Pub Date : 2020-04-01DOI: 10.30500/IVSA.2020.213380.1206
A. M. Saidu, S. T. Fadason, G. E. Ochube, S. Adamu
Objective- Comparative evaluation of standing and lateral recumbent restraint positions for rumenotomy based on transforming growth factor-β (TGF-β) concentrations of Kano-Brown goats (KBGs).Design- Experimental studyAnimals- Eighteen KBGs of both sexes diagnosed of rumen foreign body impaction (RFBI), were allocated to groups A, B and D. Six other KBGs free of RFBI were assigned to group C as control.Procedures- Groups A and B were restrained in lateral recumbency position while group D in a fabricated mobile small ruminant surgical chute (MSRSC) in a standing fashion. Serum samples stored at -20 ℃ until ELISA, were obtained pre-rumenotomy (Pre) and post-rumenotomy, at 0, 5, 24, 48 and 72 hours, and subsequently at weeks 1, 2, and 3. Group C had no surgery while A, B and D had rumen skin clamp fixation, stay suture rumenotomy and mobile small ruminant surgical chute rumenotomy, respectively. Results- The post-rumenotomy mean concentrations of TGF-β for groups A, B and D at 0 hour (81.97 ± 24.12, 71.26 ± 10.28 and 58.51 ± 6.44 ng/L, respectively) were higher than the mean pre-rumenotomy values (38.34 ± 3.66, 41.31 ± 4.90 and 44.91 ±4.10 ng/L, respectively) but were not significantly different (P > 0.05). As the mean TGF-β concentration in the males of the different experimental groups did not differ significantly (P > 0.05), the females of group B had significantly higher (P < 0.05) mean concentrations than those of group D and C females at 48 hours post-rumenotomy. Conclusions and Clinical Relevance- Lateral recumbency restraint position rumenotomy was associated with more severe post-surgical stress than standing restraint based on role switching of the TGF-β in this study. This suggests comparative advantage of standing recumbency restraint rumenotomy over the conventional lateral recumbency restraints position in goats.
{"title":"Comparative Evaluation of Standing and Lateral Recumbency Restraint Positions for Rumenotomy Based on Transforming Growth Factor-β Responses in Kano-Brown Goats","authors":"A. M. Saidu, S. T. Fadason, G. E. Ochube, S. Adamu","doi":"10.30500/IVSA.2020.213380.1206","DOIUrl":"https://doi.org/10.30500/IVSA.2020.213380.1206","url":null,"abstract":"Objective- Comparative evaluation of standing and lateral recumbent restraint positions for rumenotomy based on transforming growth factor-β (TGF-β) concentrations of Kano-Brown goats (KBGs).Design- Experimental studyAnimals- Eighteen KBGs of both sexes diagnosed of rumen foreign body impaction (RFBI), were allocated to groups A, B and D. Six other KBGs free of RFBI were assigned to group C as control.Procedures- Groups A and B were restrained in lateral recumbency position while group D in a fabricated mobile small ruminant surgical chute (MSRSC) in a standing fashion. Serum samples stored at -20 ℃ until ELISA, were obtained pre-rumenotomy (Pre) and post-rumenotomy, at 0, 5, 24, 48 and 72 hours, and subsequently at weeks 1, 2, and 3. Group C had no surgery while A, B and D had rumen skin clamp fixation, stay suture rumenotomy and mobile small ruminant surgical chute rumenotomy, respectively. Results- The post-rumenotomy mean concentrations of TGF-β for groups A, B and D at 0 hour (81.97 ± 24.12, 71.26 ± 10.28 and 58.51 ± 6.44 ng/L, respectively) were higher than the mean pre-rumenotomy values (38.34 ± 3.66, 41.31 ± 4.90 and 44.91 ±4.10 ng/L, respectively) but were not significantly different (P > 0.05). As the mean TGF-β concentration in the males of the different experimental groups did not differ significantly (P > 0.05), the females of group B had significantly higher (P < 0.05) mean concentrations than those of group D and C females at 48 hours post-rumenotomy. Conclusions and Clinical Relevance- Lateral recumbency restraint position rumenotomy was associated with more severe post-surgical stress than standing restraint based on role switching of the TGF-β in this study. This suggests comparative advantage of standing recumbency restraint rumenotomy over the conventional lateral recumbency restraints position in goats.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":"15 1","pages":"24-31"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47315856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.30500/IVSA.2020.205918.1202
Pravin Mishra, M. Mahmud, V. Yadav, Moinul Hasan
Case Description- Umbilical hernia is occasionally seen with different levels of complexity in animals This emergency condition requires quick diagnosis and is corrected with various surgical approaches. The aim of this paper is to report the surgical correction of an eviscerated umbilical hernia with extensive adhesion in a bovine calf. Twenty days old indigenous male bovine calf was presented for surgical treatment of an umbilical hernia with extensive adhesion and evisceration.Clinical Findings- Physical examination through palpation revealed evisceration of umbilical content with extensive adhesion. Treatment and Outcome- The surgical procedure was carried out aseptically following standard procedure. The bovine calf recovered without any complication two weeks after surgery.Clinical Relevance- It can be concluded that surgical management along with administration of antibiotic, antihistaminic and anti-inflammatory drugs are effective for successful management of eviscerated umbilical hernia with extensive adhesion in the bovine calf
{"title":"Umbilical Hernia with Extensive Adhesion and Evisceration in a Bovine Calf","authors":"Pravin Mishra, M. Mahmud, V. Yadav, Moinul Hasan","doi":"10.30500/IVSA.2020.205918.1202","DOIUrl":"https://doi.org/10.30500/IVSA.2020.205918.1202","url":null,"abstract":"Case Description- Umbilical hernia is occasionally seen with different levels of complexity in animals This emergency condition requires quick diagnosis and is corrected with various surgical approaches. The aim of this paper is to report the surgical correction of an eviscerated umbilical hernia with extensive adhesion in a bovine calf. Twenty days old indigenous male bovine calf was presented for surgical treatment of an umbilical hernia with extensive adhesion and evisceration.Clinical Findings- Physical examination through palpation revealed evisceration of umbilical content with extensive adhesion. Treatment and Outcome- The surgical procedure was carried out aseptically following standard procedure. The bovine calf recovered without any complication two weeks after surgery.Clinical Relevance- It can be concluded that surgical management along with administration of antibiotic, antihistaminic and anti-inflammatory drugs are effective for successful management of eviscerated umbilical hernia with extensive adhesion in the bovine calf","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":"15 1","pages":"92-95"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43443020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.22034/IVSA.2019.183999.1184
S. Maleki, A. Zakian, A. Valizadeh, A. Raisi
Case Description- A five-year-old Arabian stallion weighing approximately 300 kg with large infected chronic torn wound on the neck and pectoral region 5 days after IM injection of flunixin meglumine with history of anorexia, depression and lack of response to antibacterial treatment referred to the Veterinary Teaching Hospital of Lorestan University. Clinical Findings- The clinical symptoms observed during the examination were hematuria and watery diarrhea with very large skin laceration in the affected area. External examination revealed the infectious cervical and pectoral muscles and necrosed skin with purulent discharge and odorous smell. Skin and surrounding tissues were warm, edematous and swelled.Treatment and Outcomes- Surgical treatment started with physical debridement and maggot therapy using Lucilia (Phaenicia) sericata. Then medical treatment continued with intravenous fluid therapy, antimicrobial and anti-inflammatory drugs (NSAID) along with topical treatment. Clinical Relevance- The present case demonstrates the serious complications that can occur following non-sterile IM injections and/or as a consequence of flunixin meglumine IM administration. An aggressive pharmacological and surgical therapy is very essential in similar cases. In conclusion, successful management of the cutaneo-muscular necrosis depends upon the condition of wound and selection of proper antibacterial drugs along with early surgical intervention.
{"title":"Cutaneo-Muscular Necrosis of Cervical and Pectoral Region Following Intramuscular Injection of Flunixin Meglumine in an Arabian Stallion","authors":"S. Maleki, A. Zakian, A. Valizadeh, A. Raisi","doi":"10.22034/IVSA.2019.183999.1184","DOIUrl":"https://doi.org/10.22034/IVSA.2019.183999.1184","url":null,"abstract":"Case Description- A five-year-old Arabian stallion weighing approximately 300 kg with large infected chronic torn wound on the neck and pectoral region 5 days after IM injection of flunixin meglumine with history of anorexia, depression and lack of response to antibacterial treatment referred to the Veterinary Teaching Hospital of Lorestan University. Clinical Findings- The clinical symptoms observed during the examination were hematuria and watery diarrhea with very large skin laceration in the affected area. External examination revealed the infectious cervical and pectoral muscles and necrosed skin with purulent discharge and odorous smell. Skin and surrounding tissues were warm, edematous and swelled.Treatment and Outcomes- Surgical treatment started with physical debridement and maggot therapy using Lucilia (Phaenicia) sericata. Then medical treatment continued with intravenous fluid therapy, antimicrobial and anti-inflammatory drugs (NSAID) along with topical treatment. Clinical Relevance- The present case demonstrates the serious complications that can occur following non-sterile IM injections and/or as a consequence of flunixin meglumine IM administration. An aggressive pharmacological and surgical therapy is very essential in similar cases. In conclusion, successful management of the cutaneo-muscular necrosis depends upon the condition of wound and selection of proper antibacterial drugs along with early surgical intervention.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":"15 1","pages":"85-91"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42224867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.22034/IVSA.2020.218557.1209
Masoumeh Moradi-Ozarlou, S. Javanmardi, H. Tayefi, M. Ashrafizadeh
Objective- The purpose of this study was to evaluate the protective impacts of Plantago. major (P. major) against the adverse effects resulted from testicular ischemia/reperfusion (I/R) on kidney and liver.Design- Experimental study.Animals- Twenty-four male rats.Procedures- The testicular I/R was induced by firstly anesthetizing rats using ketamine and xylazine and then, incising the skin of testis region. After the stimulation of testicular I/R by rotating the testis in clockwise direction, fixing for 2 hours and then, re-rotating testis. Then, P. major was administered through intraperitoneal route at the dose of 50 and 100 mg/kg for 14 days. The liver and kidney samples were used for histopathological investigation.Results- It was found that testicular I/R negatively affects the kidney and liver as it was demonstrated in histopathological samples. Degeneration of hepatocytes, necrosis, hyperemia in sinusoids and infiltration of inflammatory cells were found in liver. Similarly, the hyperemia, necrosis, and infiltration of inflammatory cells were observed in the kidney. Administration of P. major diminished significantly these harmful effects with better results at the dose of 100 mg/kg.Conclusion and Clinical Relevance- It is suggested that treatment of rats with P. major is beneficial in terms of reducing the adverse effects of testicular I/R on the kidney and liver tissues and this procedure can be applied in the clinical trials.
{"title":"Hepato- and Reno-Protective Impacts of Plantago major in Rats: An Experimental Model of Testicular Ischemia/Reperfusion","authors":"Masoumeh Moradi-Ozarlou, S. Javanmardi, H. Tayefi, M. Ashrafizadeh","doi":"10.22034/IVSA.2020.218557.1209","DOIUrl":"https://doi.org/10.22034/IVSA.2020.218557.1209","url":null,"abstract":"Objective- The purpose of this study was to evaluate the protective impacts of Plantago. major (P. major) against the adverse effects resulted from testicular ischemia/reperfusion (I/R) on kidney and liver.Design- Experimental study.Animals- Twenty-four male rats.Procedures- The testicular I/R was induced by firstly anesthetizing rats using ketamine and xylazine and then, incising the skin of testis region. After the stimulation of testicular I/R by rotating the testis in clockwise direction, fixing for 2 hours and then, re-rotating testis. Then, P. major was administered through intraperitoneal route at the dose of 50 and 100 mg/kg for 14 days. The liver and kidney samples were used for histopathological investigation.Results- It was found that testicular I/R negatively affects the kidney and liver as it was demonstrated in histopathological samples. Degeneration of hepatocytes, necrosis, hyperemia in sinusoids and infiltration of inflammatory cells were found in liver. Similarly, the hyperemia, necrosis, and infiltration of inflammatory cells were observed in the kidney. Administration of P. major diminished significantly these harmful effects with better results at the dose of 100 mg/kg.Conclusion and Clinical Relevance- It is suggested that treatment of rats with P. major is beneficial in terms of reducing the adverse effects of testicular I/R on the kidney and liver tissues and this procedure can be applied in the clinical trials.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":"15 1","pages":"78-84"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49367858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.22034/IVSA/IVSA.2019.201547.1200
M. Sadeghi, Shayan Kalantari, F. Gharib, F. Faedmaleki, A. Yousefi
Objective- Cutaneous wound healing is an essential physiological process consisting of the collaboration of many cell strains and their products. Initiation of new management for treatment of wound infections caused by multidrug resistant Staphylococcus aureus is required. The aim of the present study was to assess wound healing activity of Ferula assa-foetida loaded chitosan nanoparticle biofilm in methicillin resistant S. aureus (MRSA) infected wounds in rats. Design- Experimental study Animals- Forty eight male healthy Wistar rats. Procedures- The animals were randomized into four groups of 12 animals each. In group I, the wounds were infected with MRSA and only treated with 0.1 mL the sterile saline 0.9% solution. In group II, the infected wounds were dressed with chitosan nanoparticles biofilm. In group III, animals with infected wounds were treated with 0.1 mL topical application of Ferula assa-foetida. In group IV, animals with infected wounds were dressed with Ferula assa-foetida loaded chitosan nanoparticles biofilm. Results- Microbiological examination, planimetric, biomechanical, histological and quantitative morphometric studies and determination of hydroxyproline levels showed that there was significant difference between animals in group IV compared to other groups (p = 0.001). Conclusion and Clinical Relevance- Ferula assa-foetida loaded chitosan nanoparticles biofilm could be useful for treatment of MRSA infected wounds in diabetes.
{"title":"Influence of Ferula assa-foetida Loaded Chitosan Nanoparticle Biofilm on Wound Healing in Full-Thickness Wounds Infected with Methicillin Resistant Staphylococcus aureus","authors":"M. Sadeghi, Shayan Kalantari, F. Gharib, F. Faedmaleki, A. Yousefi","doi":"10.22034/IVSA/IVSA.2019.201547.1200","DOIUrl":"https://doi.org/10.22034/IVSA/IVSA.2019.201547.1200","url":null,"abstract":"Objective- Cutaneous wound healing is an essential physiological process consisting of the collaboration of many cell strains and their products. Initiation of new management for treatment of wound infections caused by multidrug resistant Staphylococcus aureus is required. The aim of the present study was to assess wound healing activity of Ferula assa-foetida loaded chitosan nanoparticle biofilm in methicillin resistant S. aureus (MRSA) infected wounds in rats. Design- Experimental study Animals- Forty eight male healthy Wistar rats. Procedures- The animals were randomized into four groups of 12 animals each. In group I, the wounds were infected with MRSA and only treated with 0.1 mL the sterile saline 0.9% solution. In group II, the infected wounds were dressed with chitosan nanoparticles biofilm. In group III, animals with infected wounds were treated with 0.1 mL topical application of Ferula assa-foetida. In group IV, animals with infected wounds were dressed with Ferula assa-foetida loaded chitosan nanoparticles biofilm. Results- Microbiological examination, planimetric, biomechanical, histological and quantitative morphometric studies and determination of hydroxyproline levels showed that there was significant difference between animals in group IV compared to other groups (p = 0.001). Conclusion and Clinical Relevance- Ferula assa-foetida loaded chitosan nanoparticles biofilm could be useful for treatment of MRSA infected wounds in diabetes.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":"15 1","pages":"42-52"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47752375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.30500/IVSA.2020.238408.1219
H. Jalilpour, A. Meimandi-Parizi, A. Khodakaram-Tafti, M. Ahrari-Khafi, S. Hashemi
Objective- Tibiotarsal bone is the most commonly fractured long bone in small companion birds. The treatment options are basically limited to tape splinting the leg due to anatomical limitations. The goal of this study was to investigate intramedullary pinning (IM pin) as an alternative treatment option. Design- Experimental study Animals- Thirty mature budgerigars with an average weight of 30 g. Procedures- The birds underwent mid shaft tibiotarsus osteotomy and the fractures were managed by tape splinting or IM pining in each group. The IM pins and splints were removed at 21st day after surgery. Radiology was performed at 0, 7, 14, 21 and 28 days after surgery. Histopathological and biomechanical evaluations were performed on specimens by day 28. Stability on palpation, lameness scores and mortality rate were recorded. Results- Radiography showed perfect bone healing in the IM pin group versus the presence of malunion and deformity in the splint group. Histopathology demonstrated a more advanced bone healing in the IM pin group, characterized by the dominance of new bone trabeculae and new cortex formation with very little fibrous tissue. Biomechanical tests revealed significantly higher yield load, ultimate load, stiffness, and absorbed energy in the IM pin group (p <0.05). Lameness scores were significantly better in the tape splint group (p <0.05) and the mortality rate was 0 in the splint group versus 33% in the IM pin group. Conclusion and Clinical relevance- Although IM pinning showed a more advanced level of bone healing radiographically, histopathologically, and biomechanically, the higher mortality rate and higher lameness scores make it a less desirable choice for pet birds. IM pinning technique did not prove to be as safe as the tape splintage technique. Tape splinting remains the gold standard in managing the fractures of the tibiotarsal bone in budgerigars as it offers low risk and high acceptability.
{"title":"Intramedullary Pining versus Tape Splinting for Fixation of Tibiotarsal Fractures in Small Cage Birds: An Experimental Study","authors":"H. Jalilpour, A. Meimandi-Parizi, A. Khodakaram-Tafti, M. Ahrari-Khafi, S. Hashemi","doi":"10.30500/IVSA.2020.238408.1219","DOIUrl":"https://doi.org/10.30500/IVSA.2020.238408.1219","url":null,"abstract":"Objective- Tibiotarsal bone is the most commonly fractured long bone in small companion birds. The treatment options are basically limited to tape splinting the leg due to anatomical limitations. The goal of this study was to investigate intramedullary pinning (IM pin) as an alternative treatment option. Design- Experimental study Animals- Thirty mature budgerigars with an average weight of 30 g. Procedures- The birds underwent mid shaft tibiotarsus osteotomy and the fractures were managed by tape splinting or IM pining in each group. The IM pins and splints were removed at 21st day after surgery. Radiology was performed at 0, 7, 14, 21 and 28 days after surgery. Histopathological and biomechanical evaluations were performed on specimens by day 28. Stability on palpation, lameness scores and mortality rate were recorded. Results- Radiography showed perfect bone healing in the IM pin group versus the presence of malunion and deformity in the splint group. Histopathology demonstrated a more advanced bone healing in the IM pin group, characterized by the dominance of new bone trabeculae and new cortex formation with very little fibrous tissue. Biomechanical tests revealed significantly higher yield load, ultimate load, stiffness, and absorbed energy in the IM pin group (p <0.05). Lameness scores were significantly better in the tape splint group (p <0.05) and the mortality rate was 0 in the splint group versus 33% in the IM pin group. Conclusion and Clinical relevance- Although IM pinning showed a more advanced level of bone healing radiographically, histopathologically, and biomechanically, the higher mortality rate and higher lameness scores make it a less desirable choice for pet birds. IM pinning technique did not prove to be as safe as the tape splintage technique. Tape splinting remains the gold standard in managing the fractures of the tibiotarsal bone in budgerigars as it offers low risk and high acceptability.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":"15 1","pages":"115-122"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46653742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.22034/IVSA.2019.164931.1171
A. Amniattalab, Kambiz Valiei
Case description: This report describes the simultaneous occurrence of fibrosarcoma and a urolith in the urinary bladder of a 12-year-old female terrier dog that was confirmed by pathology after excisional surgery. Clinical findings: The dog had some clinical signs such as frequent urination, hematuria and dysuria with anorexia and urinary tenesmus. Radiography confirmed the presence of a cystolith that was removed by surgery. During surgery, a solitary, pedunculated and round mass that had grown from mucosal tissue to the bladder space was observed. The mass was removed by excisional surgery and its pathologic section was prepared and stained by Hematoxylin and Eosin (H&E) and Masson’s trichrome methods. Microscopic findings in the tissue of the mass such as spindle fibroblastic cells with mild to moderate cellular pleomorphism and nuclear hyperchromasia, presence of mild mitosis figures, and chronic inflammation revealed the nature of the mass as a low-grade fibrosarcoma.Treatment and outcome: The cystolith was removed during depletion of the bladder and fibrosarcoma was removed by surgery to prevent further enlargement of the tumor and occupy the bladder space. Moreover, antibiotic therapy to avoid secondary infection was performed. Post-operation monitoring of the patient showed that there was no evidence for recurrence of the tumor within 3 months after surgery. Clinical relevance: Given the findings of this report, an occurrence of bladder fibrosarcoma has non-specific clinical signs that may challenge its differential diagnosis from other urinary-tract lesions.
{"title":"A Rare Urinary Bladder Fibrosarcoma with a Cystolith in a Dog","authors":"A. Amniattalab, Kambiz Valiei","doi":"10.22034/IVSA.2019.164931.1171","DOIUrl":"https://doi.org/10.22034/IVSA.2019.164931.1171","url":null,"abstract":"Case description: This report describes the simultaneous occurrence of fibrosarcoma and a urolith in the urinary bladder of a 12-year-old female terrier dog that was confirmed by pathology after excisional surgery. Clinical findings: The dog had some clinical signs such as frequent urination, hematuria and dysuria with anorexia and urinary tenesmus. Radiography confirmed the presence of a cystolith that was removed by surgery. During surgery, a solitary, pedunculated and round mass that had grown from mucosal tissue to the bladder space was observed. The mass was removed by excisional surgery and its pathologic section was prepared and stained by Hematoxylin and Eosin (H&E) and Masson’s trichrome methods. Microscopic findings in the tissue of the mass such as spindle fibroblastic cells with mild to moderate cellular pleomorphism and nuclear hyperchromasia, presence of mild mitosis figures, and chronic inflammation revealed the nature of the mass as a low-grade fibrosarcoma.Treatment and outcome: The cystolith was removed during depletion of the bladder and fibrosarcoma was removed by surgery to prevent further enlargement of the tumor and occupy the bladder space. Moreover, antibiotic therapy to avoid secondary infection was performed. Post-operation monitoring of the patient showed that there was no evidence for recurrence of the tumor within 3 months after surgery. Clinical relevance: Given the findings of this report, an occurrence of bladder fibrosarcoma has non-specific clinical signs that may challenge its differential diagnosis from other urinary-tract lesions.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":"14 1","pages":"181-187"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44267764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.22034/IVSA.2019.178442.1182
H. Akbari, P. Mohajeri, S. Kazemi-Darabadi, J. Ashrafihelan, A. Alirezalu
Objective- This study examined the effect of Crataegus hydroalcoholic extract (CHE) on intestinal ischemia-reperfusion (I/R) in rats. Design- Experimental study Animals- 25 adult male Wistar rats Procedures- Rats weighing 200±25 g were randomly divided into five individual groups as follows: sham group without intestinal I/R, control group with intestinal I/R, and treatment groups with intestinal I/R and 10 days oral administration of CHE at doses of 25, 50 and 100 mg/kg. Intestinal I/R was accomplished by occlusion of the cranial mesenteric artery for 30 min, followed by 60 min reperfusion. Then tissue sections of jejunum were prepared and stained with hematoxylin-eosin. Histopathological lesions including hyperemia, hemorrhage, necrohemorrhagic inflammation, and villi destruction were scored as mild, moderate and severe. Results- In histopathologic evaluation, sham and control group showed the minimum and maximum injury, respectively. The mean scores of necrohemorrhagic inflammation and villi destruction significantly decreased in 25 mg/kg CHE group compared to control. However, hyperemia and hemorrhage did not change in comparison to control (p>0.007). In the group of 50 mg/kg CHE, no pathologic lesions were observed and the results were similar to those in the sham group. The mean scores of hyperemia and necrohemorrhagic inflammation in the 100 mg/kg CHE group had no significant difference with the control group. However, the mean rank of hemorrhage and villi destruction was significantly lower than control and higher than the sham group (p<0.007). Conclusion and clinical relevance- The findings of this study indicate that CHE at the dose of 50 mg/kg has the most protective effect against intestinal I/R injury in a rat model. Therefore, Crataegus can be a promising compound against intestinal I/R injuries.
{"title":"Protective Effect of Crataegus Hydroalcoholic Extract on Intestinal Ischemia-Reperfusion Injury in a Rat Model","authors":"H. Akbari, P. Mohajeri, S. Kazemi-Darabadi, J. Ashrafihelan, A. Alirezalu","doi":"10.22034/IVSA.2019.178442.1182","DOIUrl":"https://doi.org/10.22034/IVSA.2019.178442.1182","url":null,"abstract":"Objective- This study examined the effect of Crataegus hydroalcoholic extract (CHE) on intestinal ischemia-reperfusion (I/R) in rats. Design- Experimental study Animals- 25 adult male Wistar rats Procedures- Rats weighing 200±25 g were randomly divided into five individual groups as follows: sham group without intestinal I/R, control group with intestinal I/R, and treatment groups with intestinal I/R and 10 days oral administration of CHE at doses of 25, 50 and 100 mg/kg. Intestinal I/R was accomplished by occlusion of the cranial mesenteric artery for 30 min, followed by 60 min reperfusion. Then tissue sections of jejunum were prepared and stained with hematoxylin-eosin. Histopathological lesions including hyperemia, hemorrhage, necrohemorrhagic inflammation, and villi destruction were scored as mild, moderate and severe. Results- In histopathologic evaluation, sham and control group showed the minimum and maximum injury, respectively. The mean scores of necrohemorrhagic inflammation and villi destruction significantly decreased in 25 mg/kg CHE group compared to control. However, hyperemia and hemorrhage did not change in comparison to control (p>0.007). In the group of 50 mg/kg CHE, no pathologic lesions were observed and the results were similar to those in the sham group. The mean scores of hyperemia and necrohemorrhagic inflammation in the 100 mg/kg CHE group had no significant difference with the control group. However, the mean rank of hemorrhage and villi destruction was significantly lower than control and higher than the sham group (p<0.007). Conclusion and clinical relevance- The findings of this study indicate that CHE at the dose of 50 mg/kg has the most protective effect against intestinal I/R injury in a rat model. Therefore, Crataegus can be a promising compound against intestinal I/R injuries.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":"14 1","pages":"133-141"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45770155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.22034/IVSA.2019.173611.1177
A. Mousavi, G. Abedi, A. Jahandideh, S. Hesaraki
Objective- Because of the several differences between avian and mammalian physiology and anatomy, avian anesthesia requires to be more attentive. The aim of this study was to determine a safe injectable anesthetic agent that had more compatibility with the avian features. Design- Experimental study Animals- Twelve male pigeons Procedure- The pigeons weighing 302±35 g (mean±SD) were divided into two groups (n=6). In group 1, midazolam (6 mg/kg,-IM) and in group 2, metamizole (500 mg/kg,-IM) were administrated as the pre-anesthetic agents and thereafter, propofol (8 mg/kg,-IV) was injected as the main anesthetic drug in both groups. The serum enzymatic changes were analyzed before and 1 hour after the last injection. Histopathological examinations of the liver and kidneys were also evaluated in terms of possible damages to the tissue. Results- The results of blood biochemistry evaluation in group 1 showed significant changes in the levels of AST and LDH before and after the injections (p 0.05). Conclusion and clinical relevance- Based on the results, metamizole and propofol combination showed that is safer than midazolam and propofol in terms of blood biochemical and histopathological evaluations and is more compatible with pigeons.
{"title":"Histopathological and Serum Enzyme Changes of Propofol Combined with Pre-Anesthetic Agents in Domestic Pigeons (Columba livia)","authors":"A. Mousavi, G. Abedi, A. Jahandideh, S. Hesaraki","doi":"10.22034/IVSA.2019.173611.1177","DOIUrl":"https://doi.org/10.22034/IVSA.2019.173611.1177","url":null,"abstract":"Objective- Because of the several differences between avian and mammalian physiology and anatomy, avian anesthesia requires to be more attentive. The aim of this study was to determine a safe injectable anesthetic agent that had more compatibility with the avian features. Design- Experimental study Animals- Twelve male pigeons Procedure- The pigeons weighing 302±35 g (mean±SD) were divided into two groups (n=6). In group 1, midazolam (6 mg/kg,-IM) and in group 2, metamizole (500 mg/kg,-IM) were administrated as the pre-anesthetic agents and thereafter, propofol (8 mg/kg,-IV) was injected as the main anesthetic drug in both groups. The serum enzymatic changes were analyzed before and 1 hour after the last injection. Histopathological examinations of the liver and kidneys were also evaluated in terms of possible damages to the tissue. Results- The results of blood biochemistry evaluation in group 1 showed significant changes in the levels of AST and LDH before and after the injections (p 0.05). Conclusion and clinical relevance- Based on the results, metamizole and propofol combination showed that is safer than midazolam and propofol in terms of blood biochemical and histopathological evaluations and is more compatible with pigeons.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":"14 1","pages":"105-115"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43104090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.22034/IVSA.2019.184494.1185
A. Raisi, H. Norouzian, Ehsanolah Amini, Armin Barouti, Karin Gohardehi, M. Mohajer
Case description- A 2 years old common mynah (Acridotheres tristis) of unknown sex, weighing 180 g, with history of lack of appetite and depression was referred to the veterinary hospital of Lorestan University. Clinical findings- Clinical signs included: anorexia, depression and diarrhea. Lateral radiograph showed a soft tissue opacity foreign body within the body with its distal end, seemingly in the ventriculus and its proximal end extending to the thoracic esophagus. Treatment and outcome- Because the foreign body can cause obstruction, the decision was made to remove the foreign body by surgery technique. The feathers at the incision site were plucked and the skin was prepared in the usual surgical procedure. An incision (2cm) was made along the ventral midline and after tenting the abdominal musculature and O2 was distributed in the abdominal cavity. Then ventriculus was approached through an initial stab incision in the mid-portion of the ventricular and the foreign body, which was a sewing elastic band, was pulled out slowly with a small mosquito hemostat. Clinical relevance- For removing of a foreign body in GI tract of birds several techniques were reported that depended on size, composition and position of FB in GI tract. In this mynah, due to the position of FB in ventricular cavity, celiotomy method was used. In abdominal surgery changes in the mechanical properties of the respiratory system, may reduce the volume of breathing. So, for preventing of hypoxia, using of O2 is useful.
{"title":"Removing of Ventricular Foreign Body in a Common Mynah (Acridotheres tristis) by Celiotomy Technique: Case Report","authors":"A. Raisi, H. Norouzian, Ehsanolah Amini, Armin Barouti, Karin Gohardehi, M. Mohajer","doi":"10.22034/IVSA.2019.184494.1185","DOIUrl":"https://doi.org/10.22034/IVSA.2019.184494.1185","url":null,"abstract":"Case description- A 2 years old common mynah (Acridotheres tristis) of unknown sex, weighing 180 g, with history of lack of appetite and depression was referred to the veterinary hospital of Lorestan University. Clinical findings- Clinical signs included: anorexia, depression and diarrhea. Lateral radiograph showed a soft tissue opacity foreign body within the body with its distal end, seemingly in the ventriculus and its proximal end extending to the thoracic esophagus. Treatment and outcome- Because the foreign body can cause obstruction, the decision was made to remove the foreign body by surgery technique. The feathers at the incision site were plucked and the skin was prepared in the usual surgical procedure. An incision (2cm) was made along the ventral midline and after tenting the abdominal musculature and O2 was distributed in the abdominal cavity. Then ventriculus was approached through an initial stab incision in the mid-portion of the ventricular and the foreign body, which was a sewing elastic band, was pulled out slowly with a small mosquito hemostat. Clinical relevance- For removing of a foreign body in GI tract of birds several techniques were reported that depended on size, composition and position of FB in GI tract. In this mynah, due to the position of FB in ventricular cavity, celiotomy method was used. In abdominal surgery changes in the mechanical properties of the respiratory system, may reduce the volume of breathing. So, for preventing of hypoxia, using of O2 is useful.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":"14 1","pages":"188-192"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42484136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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