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The Delta Variant: The Choice between Spreading Vaccines or Guns 德尔塔变种:在传播疫苗或枪支之间的选择
Pub Date : 2021-01-01 DOI: 10.35248/2155-9597.21.S11.001
U. Cornelli
Background: The COVID-19 pandemic has affected the whole world since 2020 and, despite the vaccination programme under way, it is still not under control, apparently due to the Delta variant. Objective: To compare the death rates following the vaccination campaign in 52 countries (47 European countries, the USA, India, Russia, Brazil, and Mexico). Weekly periods between August 2020 and 26 July 2021 were considered. The correlation between the number of vaccinations, LEEDELS data (Life Expectancy, Ecological, Demographic/ Social and Lifestyle Variables) and defence expenditure will be calculated to determine which variables are connected with vaccination campaigns. Methods: The number of weekly deaths and vaccinations were retrieved for the 52 countries from the WHO coronavirus dashboard. The LEEDELS data and military expenses were taken from the Atlante Geografico Agostini 2020 and CIA World Factbook 2020-2021. The weekly death ratio was calculated considering a time lag of three weeks between infection and death. The statistical evaluation of the correlation between LEEDELS data and number of vaccinations was calculated using Spearman's ρ. Results: The death rates in the European countries considered following the start of the vaccination campaign are lower than in the other countries analysed. The data for the last week (26 July) in Europe, the USA, India, Brazil, Russia, and Mexico were 3.91, 19.03, 13.02, 21.38, 31.78, and 54.49 respectively. The LEEDELS data relating to wealth were all positively correlated with the number of shots administered, while defence expenditure was negatively correlated. Conclusion: Vaccination seems to be effective in protecting against COVID-19, but it cannot be employed as the sole measure against viral infection since there is still a threat that some countries (the USA, Russia, India, Brazil, and Mexico) export the infection in the form of the Delta or other variants. The resources to provide and administer vaccines are more fundamental than defence expenditure.
背景:自2020年以来,COVID-19大流行已经影响到全世界,尽管正在实施疫苗接种计划,但它仍然没有得到控制,显然是由于Delta变体。目的:比较52个国家(47个欧洲国家、美国、印度、俄罗斯、巴西和墨西哥)疫苗接种运动后的死亡率。考虑了2020年8月至2021年7月26日之间的每周周期。将计算疫苗接种次数、LEEDELS数据(预期寿命、生态、人口/社会和生活方式变量)和国防开支之间的相互关系,以确定哪些变量与疫苗接种运动有关。方法:从世界卫生组织冠状病毒仪表板中检索52个国家的每周死亡人数和疫苗接种人数。LEEDELS的数据和军费来自《亚特兰大地理》和《2020-2021年CIA世界概况》。考虑感染和死亡之间三周的时间滞后,计算周死亡率。利用Spearman ρ计算LEEDELS数据与接种疫苗数量之间相关性的统计评价。结果:在疫苗接种运动开始后考虑的欧洲国家的死亡率低于所分析的其他国家。上周(7月26日)欧洲、美国、印度、巴西、俄罗斯和墨西哥的数据分别为3.91、19.03、13.02、21.38、31.78和54.49。与财富有关的LEEDELS数据都与注射次数呈正相关,而国防开支呈负相关。结论:疫苗接种似乎可以有效预防COVID-19,但它不能作为预防病毒感染的唯一措施,因为一些国家(美国、俄罗斯、印度、巴西和墨西哥)仍然存在以三角洲或其他变体形式输出感染的威胁。提供和管理疫苗的资源比国防开支更为根本。
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引用次数: 1
A Case-Control Study of Risks factors for corona virus (covid 19) amongHealth Care Worker 医护人员感染冠状病毒(covid - 19)危险因素的病例对照研究
Pub Date : 2021-01-01 DOI: 10.35248/2155-9597.21.12.392
B. Barakzaie
Background and Aim: The ongoing epidemics of coronavirus disease 2019 (COVID-19) have caused serious problems on public health, particularly affecting the health care workers worldwide. There are limited data on number of staff affected by this serious and fatal diseases in national and international level. This study aims to find out the cause of risk of virus transmission and spread among the health worker in Herat Regional Public Hospital, Herat–Afghanistan. Method: We conducted a retrospective case control study to figure out the risk factors of novel covid 19 infection amongst health care workers in Herat Regional Hospital–Afghanistan in late April 2020 approximately 2 months from first case of diseases confirmation in Afghanistan which occurred here in Herat. The staff were divided into two group each of 26. The case group (n=26) were the ones with positive PCR test, while the control group (n=26) were those health workers with same criteria with negative PCR test result, the control group were randomly selected of 178 negative PCR by an administrative colleague who did not have a role in data analysis. Both groups had close contacted with positive covid 19 patients. The data were entered in spreadsheet and analyzed using Epi info 7. Results: Regardless the type of job and place of work, the risk of infection was 4 times higher in those without prior training comparing those who had received a covid 19 training prior to exposure to the disease (OR=4:00, P<0.05, CI 95%). Mean age in the case group was slightly higher (33.9 year) comparing to the control group (30.7 year). Fever was the most common complain of both groups but more common in the case group comparing to the control (70%, 30%) respectively, this finding was significant, p=<0.05. Interestingly, shortness of breath was more common in control group comparing to the case group (30%, 7%). This was statically significant, P=<0.05 more than 50% of positive staff were belongs to two categories; nurses and residents (n=11, n=7) respectively. Comparison of sex, the place and types of job showed no significant differences in being either safe or at more risk of getting infection. Conclusion: Health care workers are at higher risk of getting and transmitting infections from/to the patients. A comprehensive training prior to any exposure to a contagious disease is mandatory to decrease the risk for infection transmission among health care workers, KAP survey may give further information and is suggested.
背景与目的:2019冠状病毒病(COVID-19)持续流行,给全球卫生工作者带来了严重的公共卫生问题。关于在国家和国际两级受这种严重和致命疾病影响的工作人员人数的数据有限。本研究旨在找出阿富汗赫拉特地区赫拉特公立医院卫生工作者之间病毒传播和传播风险的原因。方法:我们进行了一项回顾性病例对照研究,以了解2020年4月下旬在阿富汗赫拉特地区医院的医护人员中感染新型covid - 19的危险因素,该病例发生在阿富汗赫拉特地区确诊的第一例疾病约2个月后。工作人员被分成两组,每组26人。病例组(n=26)为PCR检测阳性的病例,对照组(n=26)为PCR检测阴性标准相同的卫生工作者,对照组(n=26)为PCR检测阴性的178例,由一名不参与数据分析的行政同事随机抽取。两组患者均与covid - 19阳性患者有密切接触。将数据输入电子表格并使用Epi info 7进行分析。结果:无论工作类型和工作场所如何,未接受培训的人员感染风险比接触疾病前接受过covid - 19培训的人员高4倍(OR=4:00, P<0.05, CI 95%)。病例组的平均年龄(33.9岁)略高于对照组(30.7岁)。发热是两组患者最常见的主诉,但病例组较对照组更常见(分别为70%、30%),差异有统计学意义(p=<0.05)。有趣的是,与病例组相比,对照组呼吸短促更常见(30%,7%)。这有统计学意义,P=<0.05以上的阳性员工分别属于两类;护士和住院医师分别为11名和7名。性别、地点和工作类型的比较显示,在安全性或感染风险方面没有显著差异。结论:医护人员感染和传播疾病的风险较高。在接触任何传染病之前必须进行全面的培训,以减少卫生保健工作者之间感染传播的风险,KAP调查可以提供进一步的信息,并建议进行调查。
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引用次数: 0
The Overall Consequence of Antiviral Drugs Given to Pregnant Women with COVID-19 感染COVID-19的孕妇服用抗病毒药物的总体后果
Pub Date : 2021-01-01 DOI: 10.35248/2155-9597.21.S10.002
Gamze Akpınar, Cihan Tastan
During pregnancy, the anatomical structure of the respiratory system changes, and the virus transmitted by droplets and aerosols are more easily inhaled and difficult to remove by pregnant women. Women are generally more susceptible to various pregnancy-related complications and respiratory pathogens, increasing the risk of developing adverse pregnancy and neonatal outcomes. Anecdotal evidence suggests that pregnant women do not appear to differ from the general population in terms of disease transmission, and to date, there is no evidence of vertical transmission from mother to fetus. However, in another study, it is known that members of the coronavirus family are responsible for serious complications such as miscarriage, fetal growth restriction, and congenital anomalies during pregnancy. To date, only a few studies have reported relatively higher rates of adverse birth outcomes in women affected by SARS-CoV-2 infection in late pregnancy. This literature review presents the use of drugs used for the treatment of COVID-19 disease in pregnancy and pregnancy outcomes. It is also aimed to examine the effective control and management of SARS CoV-2 infection in the pregnancy, delivery, and postpartum period in line with the existing literature and guide health personals. Large-scale epidemiological studies are needed to evaluate the course of the infection during pregnancy and the effects of the drugs used on pregnancy and fetus.
在怀孕期间,呼吸系统的解剖结构发生变化,通过飞沫和气溶胶传播的病毒更容易被孕妇吸入,难以被清除。妇女通常更容易受到各种妊娠相关并发症和呼吸道病原体的影响,从而增加了发生不良妊娠和新生儿结局的风险。坊间证据表明,孕妇在疾病传播方面似乎与一般人群没有什么不同,迄今为止,没有证据表明存在从母亲向胎儿的垂直传播。然而,在另一项研究中,已知冠状病毒家族的成员会导致严重的并发症,如流产、胎儿生长受限和怀孕期间的先天性异常。迄今为止,只有少数研究报告了妊娠后期受SARS-CoV-2感染的妇女的不良分娩结局发生率相对较高。本文献综述介绍了用于治疗COVID-19疾病的药物在妊娠期的使用和妊娠结局。结合现有文献,探讨妊娠、分娩和产后SARS - CoV-2感染的有效控制和管理,指导卫生人员。需要进行大规模流行病学研究,以评估妊娠期感染的过程以及所使用药物对妊娠和胎儿的影响。
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引用次数: 1
Prologue to Bacteriology and Detailed Study of Microscopic Organisms 细菌学与微生物详细研究前言
Pub Date : 2021-01-01 DOI: 10.35248/2155-9597.21.S11.E005
Jeremy Walton
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引用次数: 0
Dynamic Adjustment of SIR Model with the Social Permissiveness: An Actual Measure of the Infection Rate 社会容忍度下SIR模型的动态调整:感染率的实际度量
Pub Date : 2021-01-01 DOI: 10.35248/2155-9597.21.S11.003
Gerardo L. Febres
The COVID-19 pandemic has globally impacted the behavior of the social patterns affecting the disease’s contagiousness. This effect deviates the classical SIR model from reproducing the data of COVID-19 in most countries. This study incorporates a non-constant permissiveness function to the SIR model. The resulting model is computationally solved to obtain a likely permissiveness time-function. To solve the adjusted model, a technique based on a proportional-integral controller is applied. The resulting models are compared with previous results obtained by a manual iterative adjusting method.
COVID-19大流行在全球范围内影响了影响疾病传染性的社会模式的行为。这种影响偏离了经典SIR模型,无法再现大多数国家的COVID-19数据。本研究在SIR模型中加入了一个非常数许可函数。对得到的模型进行计算求解,得到一个可能的许可时间函数。为了解决调整后的模型,采用了一种基于比例积分控制器的技术。将所得模型与以往人工迭代调整方法得到的结果进行了比较。
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引用次数: 1
Characterizing the Impact of COVID-19 on the Global Stock Indices through Comparative Analysis 通过比较分析表征COVID-19对全球股票指数的影响
Pub Date : 2020-06-26 DOI: 10.21203/rs.3.rs-37727/v1
Jeffhraim Balilla
This paper shows the impact of COVID-19 on the global stock indices through the use of comparative analysis. Stock indices are presented by regions (Africa, Americas, Europe, Asia, and Oceania) and national stock indices are compared based on historical data. A 2:4 month ratio is used as a “window” for observing the changes in the movement of the price of indices from November – December 2019 and January – May 2020 respectively. COVID-19 infection count, recovery rate, and death rate are identified in each country from the first case recorded up to May 20, 2020. Based on analysis it appeared that there is no sufficient evidence to conclude that the changes in the value of indices is affected by the COVID-19 infection count (p-value = 0.9129). In Africa, only INDZI (Zimbabwe) showed a positive change of price in percentage points (1.39%) for January to May 2020 with 51 confirmed COVID-19 cases. In Asia, only SZSE (China) showed a positive mean change of price in percentage points (0.07%) in the same period with 82,971 confirmed cases. Similarly, in Europe, only OMXC20 (Denmark) showed the same with (0.09%) with 11,182 confirmed cases. In the Americas, NYSE Arca (US), Nasdaq100 (US), and MERVAL (Argentina) showed a positive mean change in price in percentage points (0.31%, 0.20%, and 0.89%) with 1,620,902 and 9,918 confirmed cases respectively. On the other hand, in Oceania, both NZX 50 (New Zealand) and S&P/ASX20 (Australia) showed a negative mean change in prices (-0.03 & -0.15) respectively. In general Asian and European indices suffered a 0.28% decrease in the mean change in daily prices as compared during November to December 2019. African indices on average stood to be the least affected with 0.11% mean change in daily prices as compared to -0.02% from November to December 2019.
本文通过比较分析的方法展示了新冠肺炎疫情对全球股指的影响。股票指数按地区(非洲、美洲、欧洲、亚洲和大洋洲)呈现,各国股票指数根据历史数据进行比较。以2:4的月比作为“窗口”,分别观察2019年11月至12月和2020年1月至5月期间指数价格的变动。从记录到2020年5月20日,确定每个国家的COVID-19感染数、康复率和死亡率。分析表明,没有足够的证据表明各指数值的变化受到COVID-19感染计数的影响(p值= 0.9129)。在非洲,2020年1月至5月,只有津巴布韦的价格出现了1.39%的正变化,确诊病例为51例。在亚洲,同期只有深圳证券交易所(中国)的确诊病例为82971例,平均价格变动为正(0.07%)。同样,在欧洲,只有丹麦的OMXC20确诊病例为11182例(0.09%)。在美洲,纽约证券交易所(NYSE Arca)(美国)、纳斯达克100指数(Nasdaq100)(美国)和MERVAL(阿根廷)的确诊病例分别为1,620,902例和9,918例,平均价格变化为正(0.31%、0.20%和0.89%)。另一方面,在大洋洲,nzx50(新西兰)和S&P/ASX20(澳大利亚)的平均价格变化分别为负(-0.03和-0.15)。总体而言,与2019年11月至12月相比,亚洲和欧洲指数的日均价格变化下降了0.28%。非洲指数受影响最小,平均每日价格变化0.11%,而2019年11月至12月的平均每日价格变化为-0.02%。
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引用次数: 2
Introduction to Microbial Diseases in Humans 人类微生物疾病导论
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.S6.001
Scott C. Rowe
Irresistible infections have significantly affected the course of mankind's set of experiences. The "dark demise" (brought about by Yersinia pestis changed the social structure of archaic Europe, in the process dispensing with roughly 33% of the populace. The results of military missions have been modified by episodes of infections, for example, loose bowels and typhus. Models incorporate Napoleon's retreat from Russia, after typhus harmed his military than the resistance powers did; the choice by the French to sell the Louisiana Territory after French troopers passed on from yellow fever in Cuba and the Gulf Coast; and the acquaintance of smallpox with the no immune populace of the New World by Europeans, subsequently encouraging the "success" and the beginning of the pilgrim age.
不可抗拒的传染病严重影响了人类一系列经历的进程。鼠疫杆菌带来的“黑暗消亡”改变了古代欧洲的社会结构,在此过程中,大约有33%的人口死亡。军事任务的结果被感染事件所改变,例如拉肚子和斑疹伤寒。模型包含了拿破仑从俄国撤退的过程,在斑疹伤寒对他的军队造成的伤害大于抵抗力量;在法国士兵在古巴和墨西哥湾沿岸感染黄热病后,法国人选择出售路易斯安那领土;以及欧洲人在新大陆对天花没有免疫力的人群中认识天花,随后鼓励了“成功”和朝圣者时代的开始。
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引用次数: 0
Microbial Associations: Nature in a Sub-Atomic Viewpoint 微生物关联:亚原子观点下的自然
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.S7.E002
S. Tachibana
The microorganism–microorganism or microorganism–have cooperations are the critical procedure to colonize and set up in a wide range of conditions. These collaborations include every biological perspective, including physiochemical changes, metabolite trade, metabolite transformation, flagging, chemotaxis and hereditary trade bringing about genotype determination. Furthermore, the foundation in the climate relies upon the species variety, since high useful repetition in the microbial network expands the serious capacity of the network, diminishing the chance of an intruder to set up in this climate. Hence, these affiliations are the consequence of a co-advancement measure that prompts the transformation and specialization, permitting the control of various specialties, by lessening biotic and abiotic stress or trading development factors and flagging. Microbial collaborations happen by the transaction of sub-atomic and hereditary data, and numerous components can be associated with this trade, for example, auxiliary metabolites, siderophores, majority detecting framework, biofilm development, and cell transduction motioning, among others. A definitive unit of collaboration is the quality articulation of every living being in light of a natural (biotic or abiotic) upgrade, which is answerable for the creation of atoms associated with these cooperations. Along these lines, in the current survey, we zeroed in on some sub-atomic components engaged with the microbial cooperation, not just in microbial–have communication, which has been abused by different audits, yet additionally in the sub-atomic methodology utilized by various microorganisms in the climate that can balance the foundation and structuration of the microbial network.
微生物-微生物或微生物-合作是在广泛条件下定植和建立的关键过程。这些合作包括每一个生物学角度,包括物理化学变化、代谢物交易、代谢物转化、标记、趋化性和遗传交易,从而确定基因型。此外,气候的基础依赖于物种的多样性,因为微生物网络中的高有用重复扩展了网络的严重能力,减少了入侵者在这种气候中建立的机会。因此,这些从属关系是促进转型和专业化的共同发展措施的结果,通过减少生物和非生物压力或交易发展因素和标记,允许控制各种专业。微生物合作是通过亚原子和遗传数据的交换而发生的,许多成分都与这种交换有关,例如,辅助代谢物、铁载体、多数检测框架、生物膜发育和细胞转导运动等。协作的最终单位是每个生物在自然(生物或非生物)升级的基础上的质量衔接,它负责与这些合作相关的原子的创造。沿着这些思路,在当前的调查中,我们将重点放在与微生物合作有关的一些亚原子成分上,而不仅仅是在微生物之间的交流中,这已经被不同的审计所滥用,此外,在气候中各种微生物所使用的亚原子方法中,可以平衡微生物网络的基础和结构。
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引用次数: 0
Isolation, Characterization and Identification of Contaminant Bacteria from Sugarcane (Saccharum officinarum L.) in vitro Culture in Tigray Biotechnology Center, Mekelle, Ethiopia 甘蔗(Saccharum officinarum L.)离体培养中污染细菌的分离、表征和鉴定
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.11.372
Tsehaye Kidus, Z. Teka
Plant tissue cultures can be contaminated by extensive diversity of bacteria and the contaminations are species specific. The contamination can reduce growth rate of shoot and root, multiplication factor, and even cause plant death. The study was conducted at Mekelle University, College of Veterinary Medicine and Tigray Biotechnology center and contaminated in vitro sugarcane culture obtained from laboratory of plant tissue culture. The objective of the study was to isolate, characterize, and identify bacteria from contaminated in vitro Sugarcane culture and to test the sensitivity of the isolates to the most commonly used antibiotics. Morphological, Gram stain, Endospore stain and Biochemical test method were used to isolate and identify the contaminates and disk diffusion method was used for the drug susceptibility test. Commonly available antibiotics were used for susceptibility testing. In the present study Escherichia, Bacillus and Micrococcus were isolated and identified as the major contaminant bacteria from in vitro sugarcane cultures. In antibacterial susceptibility test the isolates of Bacillus and Micrococcus were susceptible to Gentamicin, Chloramphenicol, Ciprofloxaciline, Tetracycline, Vancomycine, Streptomycin, Penicillin G and Kanamycine demonstrating the efficacy of these antimicrobials for the treatment of sugarcane in vitro culture contamination by incorporating in to the sugarcane media formulation while, the third isolate Escherichia were resistance to all antibiotic agents.
植物组织培养物可能受到多种细菌的污染,并且污染具有物种特异性。污染会降低茎、根的生长速度,降低繁殖因子,甚至导致植物死亡。本研究在法国麦克勒大学兽医学院和提格雷生物技术中心进行,并对植物组织培养实验室获得的甘蔗离体培养物进行污染。本研究的目的是从受污染的甘蔗体外培养物中分离、表征和鉴定细菌,并测试分离物对最常用抗生素的敏感性。采用形态学法、革兰氏染色法、内孢子染色法和生化法分离鉴定污染物,采用纸片扩散法进行药敏试验。采用常用抗生素进行药敏试验。本研究分离并鉴定了甘蔗体外培养中主要的污染菌为大肠杆菌、芽孢杆菌和微球菌。菌株对庆大霉素、氯霉素、环丙沙西林、四环素、万古霉素、链霉素、盘尼西林、卡那霉素等抗菌素均有敏感性,菌株对所有抗菌素均有耐药性。
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引用次数: 2
Micro - Nano Bubble Technology- An In-Situ Treatment for Microbial Community Changes in Urban River 微纳气泡技术——城市河流微生物群落变化的原位处理
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.S6.005
Toshiyuki Tony
Urban watercourses are essential and important to the urban ecosystem, landscape ecology and citizen’s life. However, in recent decades, rapid industrialization and urbanization has accelerated the worsening waters in urban area in China. Urban rivers are usually used as drains for sewage, industrial wastewater and even domestic garbage, which contained various pollutants. When organic pollutants are discharged to rivers, part of them is precipitated in the sediment and the others are metabolized by microbes. During the metabolism, the microbes exhaust the dissolved oxygen in the water and make the aquatic environment anoxic, which promotes the growth of anaerobic microbes. As a result, the river is in anoxic condition, showing black appearance and stinking smell. These black-odor rivers flows through the cities affect residents’ life and pose a serious threat to human health. During the metabolism, the microbes exhaust the dissolved oxygen in the water and make the aquatic environment anoxic, which promotes the growth of anaerobic microbes. As a result, the river is in anoxic condition, showing black appearance.
城市河道对城市生态系统、景观生态和市民生活至关重要。然而,近几十年来,快速的工业化和城市化加速了中国城市水域的恶化。城市河流通常被用作污水、工业废水甚至生活垃圾的排水沟,其中含有各种污染物。当有机污染物排入河流时,一部分在沉积物中沉淀,另一部分被微生物代谢。微生物在代谢过程中,将水中的溶解氧排尽,使水生环境缺氧,促进厌氧微生物的生长。结果,这条河处于缺氧状态,呈现出黑色的外观和恶臭。这些黑臭的河流流经城市,影响着居民的生活,对人体健康构成严重威胁。微生物在代谢过程中,将水中的溶解氧排尽,使水生环境缺氧,促进厌氧微生物的生长。结果,河流处于缺氧状态,呈现黑色外观。
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引用次数: 0
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Journal of Bacteriology & Parasitology
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