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High Mortality of COVID-19 Infection in Hip Fractures 髋部骨折患者感染COVID-19的高死亡率
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.S5.004
A. Fadulelmola
Following the recent pandemic caused by a novel virus, SARS-CoV-2 (COVID-19) originating in China we have investigated the effect of COVID-19 virus on the mortality of cases associated with hip fractures. Hip fracture by itself carries a significant mortality risk post injury, which was recorded to be around 7% in the first 30 days. We have presented the first evidence of high (50%) 30-day mortality in fragility hip fractures associated with COVID-19 infection.
在最近由源自中国的新型病毒SARS-CoV-2 (COVID-19)引起的大流行之后,我们调查了COVID-19病毒对髋部骨折相关病例死亡率的影响。髋部骨折本身具有显著的损伤后死亡风险,记录显示在前30天的死亡率约为7%。我们首次提出了与COVID-19感染相关的脆性髋部骨折30天死亡率高(50%)的证据。
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引用次数: 0
Treatment of parasitic diseases of voyagers and migrants 治疗航海家和移民的寄生虫病
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.S6.002
Angelico Corsetti
The development in worldwide business, travel and relocation add to the worldwide rise of certain parasitic diseases. Importation of vectors and food items may add to the development of protozoan diseases in no endemic nations. Diseases, for example, intestinal sickness are conceivably deadly, particularly in no immune patients, and result relies generally upon opportune analysis and therapy. Analysis/the board of imported parasitic diseases might be intricate particularly as certain patients may have fundamental immunosuppressive conditions, for example, HIV contamination. Significant difficulties concern the advancement of improved symptomatic methods, more secure/more powerful medication treatments and distinguishing proof of organic markers of movement and reaction to treatment. Imported parasitic sicknesses which might be communicated vertically or through blood bonding/organ gift could turn into a general wellbeing need sooner rather than later. Environmental change may influence arthropod appropriation and encourage the spread of protozoan vector-borne sicknesses. The initial segment of this audit centers around protozoan diseases in voyagers and foreigners.
全球商业、旅行和迁移的发展增加了某些寄生虫病在世界范围内的发病率。在没有流行疾病的国家,输入病媒和食品可能会加剧原生动物疾病的发展。疾病,例如肠道疾病,可以想象是致命的,特别是在没有免疫力的患者中,其结果通常取决于及时的分析和治疗。对输入性寄生虫病的分析/管理可能十分复杂,特别是因为某些病人可能患有基本的免疫抑制疾病,例如艾滋病毒污染。重大的困难涉及改进对症治疗方法的进展,更安全/更有效的药物治疗,以及区分运动和治疗反应的有机标记物的证据。可能通过垂直传播或通过血液结合/器官赠与传播的输入性寄生虫病可能很快变成一种普遍的健康需求。环境变化可能影响节肢动物的占用,并鼓励原生动物媒介传播疾病的传播。审计的最初部分围绕着旅行者和外国人的原生动物疾病展开。
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引用次数: 0
An Unusual Presentation of Extra-Nodal Pelvic Diffuse Large B-Cell Lymphoma 结外盆腔弥漫性大b细胞淋巴瘤的不寻常表现
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.11.384
Danial Z Bell, A. Ekladious
An 80 years old man with a history of Rheumatoid Arthritis and Charcot-Marie-Tooth disease presented with urinary retention, constipation, weight loss and anorexia. CT imaging showed a large presacral mass, with tissue biopsy identifying diffuse large B cell lymphoma. PET imaging did not identify any lymphadenopathy. This case illustrates a rare pelvic manifestation of a common haematological malignancy.
80岁男性,有类风湿关节炎和腓骨肌肌萎缩症病史,表现为尿潴留、便秘、体重减轻和厌食。CT显示骶前大肿块,组织活检证实弥漫性大B细胞淋巴瘤。PET成像未发现任何淋巴结病变。本病例显示了一种常见的血液恶性肿瘤的罕见盆腔表现。
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引用次数: 0
A Subtle but Effective Tool for Accelerating Drug Repurposing Against COVID-19 and Future Viral Eruptions 加速药物再利用以对抗COVID-19和未来病毒爆发的微妙但有效的工具
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.S5.005
I. Naasani
The sense of emergency worldwide due to the COVID-19 pandemic alerted medical researchers to scramble for resources and rummage around for all possible armaments to fight the deadly pandemic.
新型冠状病毒感染症(COVID-19)大流行引起的世界范围内的紧急意识,促使医学研究人员争抢资源,寻找一切可能的武器,以对抗致命的大流行。
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引用次数: 0
A Cross-Sectional Survey of Brucellosis in Small Ruminants of District Jhang, Punjab, Pakistan 巴基斯坦旁遮普Jhang地区小反刍动物布鲁氏菌病横断面调查
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.11.376
Rizwan Saeed, Hafiz Zaid Mahmood, Zulqarnain Baqar, Sanaullah
Background: Brucellosis is a bacterial zoonotic disease having a wide host range and global zoonotic importance. It has great public health importance in most of the countries, where livestock is a major source of food and income. High-risk individuals include animal handlers that are at great risk of getting an infection because bacterial transmission occurs from all body fluids from an infected animal. Objective: A randomized cross sectional survey was conducted to check the period prevalence of brucellosis in small ruminants in different areas of district Jhang. Methods: Serum samples were collected along with a questionnaire for this purpose. Different risk factors like age, sex, specie, feeding protocol, abortion history, type of herd, herd size, location were observed using a questionnaire. A total of 280 serum samples (136 caprine and 144 ovine) were collected and subjected to Rose Bengal precipitation test for screening of brucellosis. Results: Overall sero-positivity was 5.5% after confirmation with Indirect ELISA. 21 samples out of 280 were seropositive after RBPT screening and 14 out of 21 were confirmed seropositive for brucellosis by indirect ELISA. According to p value after statistical analysis, all the risk factors except feeding protocols, abortion and age in the case of sheep had no significant results. According to the odds ratio, all the selected risk factors have an association with disease prevalence. In females (6.25%) there is more sero-positivity than male (1.39%). Sheep (8.09%) had more seropositivity than goats (2.08%). Out of three age groups ( 5 years)>5 years (6.78%) animals had more seropositivity than 50 animals (10.94%) had more seropositivity than ≤ 10 (3.17%), 10-30 (1.61%) and 30-50 (10.34%).Mix animal species within-herd had more chance of sero-positivity than the pure herd. Grazing practice for feeding of animals (7.02%) had more sero-positivity than stall feeding (1.83%). Conclusion: Brucellosis was endemic in the study design area which is a risk not only for the animal’s population but also for humans.
背景:布鲁氏菌病是一种具有广泛宿主范围和全球人畜共患病重要性的细菌性人畜共患病。在大多数国家,牲畜是粮食和收入的主要来源,因此对公共卫生具有重大意义。高风险个体包括动物饲养员,他们有很大的感染风险,因为感染动物的所有体液都会传播细菌。目的:采用随机横断面调查方法,了解张区不同地区小反刍动物布鲁氏菌病的发病情况。方法:采集血清样本并填写调查问卷。采用问卷调查的方式,对年龄、性别、品种、饲养方式、流产史、畜群类型、畜群规模、地点等不同危险因素进行观察。共收集280份血清样本(136份山羊,144份绵羊),采用玫瑰孟加拉沉淀试验筛查布鲁氏菌病。结果:经间接酶联免疫吸附试验证实,血清总阳性率为5.5%。280个样本中有21个经RBPT筛查呈血清阳性,21个样本中有14个经间接ELISA证实为布鲁氏菌病血清阳性。经统计分析的p值显示,绵羊除饲养方式、流产和年龄外,其他危险因素均无显著影响。根据比值比,所有选定的危险因素都与疾病流行有关。女性(6.25%)高于男性(1.39%)。绵羊(8.09%)高于山羊(2.08%)。在3个年龄组(5岁)中,>5岁(6.78%)的动物血清阳性率高于50岁(10.94%),高于≤10岁(3.17%)、10-30岁(1.61%)和30-50岁(10.34%)。畜群内混种动物血清阳性的几率高于纯畜群。放牧饲养动物(7.02%)血清阳性率高于圈养饲养(1.83%)。结论:布鲁氏菌病在研究设计区流行,不仅对动物种群构成威胁,而且对人类也构成威胁。
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引用次数: 0
Commentary on the Role of Angiology and Vascular Surgery in the COVID-19 Pandemic 血管学和血管外科在COVID-19大流行中的作用评论
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.11.373
Bernardo Cunha Senra Barros, Aline Barbosa Maia
Currently, according to data from the World Health Organization, the number of people around the world infected with the new coronavirus, also known as Sars-CoV-2, has already passed the nine million infected mark. This new epidemic that emerged in the city of Wuhan, China, has become epidemiologically distinct from the other two viruses of the Coronavirus family already known to us and that have caused regional outbreaks in humans, thus not yet demonstrating the ability for rapid global distribution, which are the coronavirus responsible for severe acute respiratory syndrome (Sars-CoV) and the coronavirus responsible for Middle East respiratory syndrome (Mers-CoV).
目前,根据世界卫生组织的数据,全球感染新型冠状病毒(也称为Sars-CoV-2)的人数已经超过900万。在中国武汉市出现的这一新的流行病在流行病学上与我们已知的冠状病毒家族的另外两种病毒不同,这两种病毒是导致严重急性呼吸综合征(Sars-CoV)的冠状病毒和导致中东呼吸综合征(Mers-CoV)的冠状病毒,已在人类中引起区域性疫情,因此尚未显示出快速全球传播的能力。
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引用次数: 1
Lessons from the Pandemic that Need to be Understood and Learned 需要了解和学习的大流行教训
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.S5.002
I. Klepikov
The current COVID-19 pandemic has changed the rhythm and habits of our lives, and the uncertainty of forecasts, lack of effective treatment, and daily media reports about the growing number of infected people and deaths are causing alarm and concern in society.
当前的新冠肺炎大流行改变了我们的生活节奏和习惯,预测的不确定性、有效治疗的缺乏、媒体每天报道的感染人数和死亡人数不断增加,引起了社会的恐慌和担忧。
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引用次数: 0
Studies on Economic Losses of Coccidial Infection 球虫感染的经济损失研究
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.11.366
R. Sultana, Mansur-ud-din Ahmed, Zafar Iqbal Ch, M. Ahmad, B. Siddique, S. Gillani
The aim of present study was to see the effect of infection and its medication on weight gain of calves under indigenous environment. Twelve cattle calves under 3 months of age were procured and reared under standard manage mental conditions. After one week of deworming and acclimatization, calves were randomly divided into two groups and were infected with 20000 oocysts of E. bovis. Group A: Animals of this group were infected but medicated and their feed conversion ratio and body weight were recorded weekly for a period of two months. Group B: Animals of this group were kept as infected and non-medicated and their feed conversion ratio and body weight were recorded weekly for a period of two months. The economical losses due to coccidiosis in experimental calves was calculated on the basis of loss in weight gain and feed conversion ratio as compared with the control groups. It was concluded that there was significant difference (p<0.05) between weight gain and feed conversion ratio of treated animals and infected non-treated group. Weight gain and FCR of treated group A was high as compared to non-treated group B.
本研究旨在观察本地环境下感染及其药物治疗对犊牛增重的影响。获得12头3个月以下的小牛,并在标准管理的精神条件下饲养。经过1周的驱虫和适应后,将犊牛随机分为两组,分别感染2万个牛大肠杆菌卵囊。A组:感染后给药,每周记录饲料系数和体重,为期2个月。B组:感染不给药饲养,每周记录饲料系数和体重,为期2个月。根据与对照组相比的增重损失和饲料系数计算试验犊牛球虫病造成的经济损失。由此可见,处理组与未处理组的增重和饲料系数差异显著(p<0.05)。A组的增重和FCR均高于未处理的B组。
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引用次数: 1
Identification by 16S Ribosomal RNA Gene Sequencing of Lactic Acid Bacteria Producing Antibacterial Agents from Langsat Fruit (Lansium domesticum) in North Minahasa District, North Sulawesi 北苏拉威西省北米纳哈萨地区产Langsat果实抗菌剂乳酸菌的16S核糖体RNA基因测序鉴定
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.S5.003
H. J. Lawalata, M. Rengkuan, Utari Satiman
Fourty two strains Lactic Acid Bacteria (LAB) were isolated from Langsat fruit (Lansium domesticum) samples obtained from 4 districts in Minahasa, North Sulawesi. 12 isolates of lactic acid bacteria were isolated from Langsat fruit in North Minahasa District. Lactic acid bacteria have the ability to inhibit the growth of pathogenic bacteria and putrefactive bacteria. The aim of this study was to identify LAB isolates producing antibacterial agents from Langsat fruit at North Minahasa District based on identification genotypic. Identification genotypic isolat LMU7 from Langsat fruit was based on 16S rRNA gene sequencing Method. One Isolate (LMU7) had a great ability to inhibit the growth of pathogenic bacteria and putrefactive bacteria. The 16S ribosomal RNA gene from one isolate could be amplified by PCR (Polymerase Chain Reaction) and show a single band on a 2% (w/v) agarose gel. Identification by 16S Ribosomal RNA gene showed that one isolate LAB producing antibacterial agents were identified as Lactobacillus plantarum with a similarity index of approximately 99.93%.
从北苏拉威西省米纳哈萨市4个地区的朗萨特果实(Lansium domesticum)中分离到42株乳酸菌,其中从北米纳哈萨市朗萨特果实中分离到12株乳酸菌。乳酸菌具有抑制致病菌和腐菌生长的能力。本研究的目的是通过鉴定基因型对北米纳哈萨地区朗萨特果实中产生抗菌药物的乳酸菌进行分离。采用16S rRNA基因测序法对龙果LMU7进行基因型鉴定。其中一株分离物(LMU7)对病原菌和腐菌的生长有较强的抑制作用。其中一个分离物的16S核糖体RNA基因可以通过PCR(聚合酶链反应)扩增,并在2% (w/v)琼脂糖凝胶上显示单带。经16S核糖体RNA基因鉴定,1株产抗菌的乳酸菌为植物乳杆菌(Lactobacillus plantarum),相似度约为99.93%。
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引用次数: 0
Chemotherapy of Parasitic Contaminations 寄生虫污染的化疗
Pub Date : 2020-01-01 DOI: 10.35248/2155-9597.20.S6.004
U. Rowe
Parasites are creatures that live in on another living being, called the host. The parasites can be tiny or enormous enough to see with the unaided eye, and they make due by taking care of from the host. They can likewise spread parasitic contaminations, which can prompt sepsis. At times inaccurately called blood harming, sepsis is the body's regularly lethal reaction to contamination. Sepsis slaughters and handicaps millions and requires early doubt and quick treatment for endurance. Sepsis is and septic stun can result from a disease anyplace in the body, for example, pneumonia, flu, or urinary lot contaminations. Around the world, 33% of individuals who create sepsis kick the bucket. Numerous who do endure are left with extraordinary impacts, for example, post-horrible pressure issue (PTSD), constant torment and exhaustion, organ brokenness (organs don't work appropriately), and additionally removals. Harming, sepsis is the body's regularly lethal reaction to contamination. Sepsis slaughters and handicaps millions and requires early doubt and quick treatment for endurance.
寄生虫是寄生在另一种生物身上的生物,这种生物被称为宿主。这些寄生虫可以很小,也可以很大,可以用肉眼看到,它们通过照顾宿主来实现自己的目标。它们同样可以传播寄生虫污染,从而导致败血症。有时被不准确地称为血液伤害,败血症是人体对污染的常规致命反应。败血症导致数百万人死亡和致残,需要早期怀疑和快速治疗才能维持耐力。败血症是一种败血症性昏迷,可由身体任何部位的疾病引起,例如肺炎、流感或尿路污染。在世界范围内,造成败血症的人中有33%死亡。许多忍受了痛苦的人留下了巨大的影响,例如,恐怖后压力问题(PTSD),持续的折磨和疲惫,器官衰竭(器官不能正常工作),以及额外的移除。有害的败血症是人体对污染的常规致命反应。败血症导致数百万人死亡和致残,需要早期怀疑和快速治疗才能维持耐力。
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引用次数: 0
期刊
Journal of Bacteriology & Parasitology
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