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A Comparison of Three Research Methods: Logistic Regression, Decision Tree, and Random Forest to Reveal Association of Type 2 Diabetes with Risk Factors and Classify Subjects in a Military Population Logistic回归、决策树和随机森林三种研究方法在军队人群中2型糖尿病危险因素和分类研究中的比较
Pub Date : 2022-06-12 DOI: 10.5812/jamm-118525
Mohammad Saheb-Honar, M. Gholampour Dehaki, M. H. Kazemi-Galougahi, Saeed Soleiman-Meigooni
Background: Type 2 diabetes mellitus (T2DM) is one of the major non-communicable diseases, causing morbidity and mortality worldwide. There is no study on T2DM status in Iran Army Forces. Objectives: We aimed to measure the prevalence of T2DM in this population and identify variables associated with T2DM risk in order to classify individuals. Methods: Data from 3661 Iran Army Ground Forces were employed. Characteristics of the subjects with and without T2DM were compared. We examined the classification ability of logistic regression with two tree-based supervised learning algorithms, decision tree and random forest (RF). The ethical committee of AJA University of Medical Sciences approved this study by the approval code 995685. Results: The prevalence of T2DM was 3% less than in the general population. Our results showed that the incidence of T2DM increases as subjects become older. The proportions of staff members with T2DM were more than the other military ranks. T2DM is more common in obese and overweight groups. The highest prevalence of T2DM is in the subjects with high levels of lipid profile. The areas below the receiver operating characteristic curve for logistic regression, decision tree, and RF were 73.8%, 77.1%, and 97.1%, respectively. Conclusions: Age, body mass index, total cholesterol, low-density lipoprotein cholesterol, and triglyceride are associated with T2DM risk. The RF has superior classification performance in comparison with logistic regression and decision tree.
背景:2型糖尿病(T2DM)是世界范围内发病率和死亡率最高的非传染性疾病之一。目前没有关于伊朗军队T2DM状况的研究。目的:我们旨在测量该人群中2型糖尿病的患病率,并确定与2型糖尿病风险相关的变量,以便对个体进行分类。方法:采用3661名伊朗陆军地面部队人员的数据。比较2型糖尿病患者和非2型糖尿病患者的特征。我们用两种基于树的监督学习算法,决策树和随机森林(RF)来检验逻辑回归的分类能力。AJA医学科学大学伦理委员会批准本研究,批准代码995685。结果:T2DM患病率比普通人群低3%。我们的研究结果显示,T2DM的发病率随着受试者年龄的增长而增加。工作人员患2型糖尿病的比例高于其他军衔。2型糖尿病在肥胖和超重人群中更为常见。2型糖尿病患病率最高的是血脂水平高的受试者。logistic回归、决策树和RF的受试者工作特征曲线以下面积分别为73.8%、77.1%和97.1%。结论:年龄、体重指数、总胆固醇、低密度脂蛋白胆固醇和甘油三酯与T2DM风险相关。与逻辑回归和决策树相比,该方法具有更好的分类性能。
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引用次数: 3
COVID-19 in Continental Africa 非洲大陆的COVID-19
Pub Date : 2022-06-09 DOI: 10.5812/jamm-120425
L. Moradi
Background: In late December 2019, the emerging disease of COVID- 19 was first diagnosed in China. It was caused by a coronavirus and caused limitations in most parts of the world. Objectives: We investigated the epidemiology of COVID-19 in continental Africa. Methods: This ecological study described the epidemiological features of COVID-19 in Africa. We extracted the data related to identified definitive cases and deaths due to this disease and other information from the reports released by the World Health Organization and transferred the data to the SPSS 24 software. Also, the fatality rate was separately determined for each country. Results: The highest number of cases diagnosed with COVID-19 was in South Africa with 2907619 cases, and the highest number of deaths due to COVID19 was found in South Africa with 87922 cases. The highest case fatality rate was in Liberia, with 4.93%. Conclusions: Prevention of COVID-19 transmission is possible by vaccinating most age groups in the community and observing social distance. Upgrading diagnostic equipment and identifying healthy and quarantined carriers is also effective in reducing COVID- 19 transmission. The cooperation of health officials and volunteers is effective in more fully identifying patients and enforcing quarantine rules. The World Health Organization provides financial support, diagnostic equipment, and vaccines for low- and middle-income countries in all parts of the world, especially in Africa. Financial support from charitable groups to provide insurance services and medical and pharmaceutical equipment is an effective help in reducing the damage of COVID- 19.
背景:2019年12月下旬,中国首次发现新发疾病COVID- 19。它是由冠状病毒引起的,在世界大部分地区造成了限制。目的:调查COVID-19在非洲大陆的流行病学。方法:本生态研究描述了2019冠状病毒病在非洲的流行病学特征。我们从世界卫生组织发布的报告中提取与确诊病例和死亡有关的数据以及其他信息,并将数据转移到SPSS 24软件中。此外,每个国家的死亡率是单独确定的。结果:南非新冠肺炎确诊病例最多,为2907619例;南非新冠肺炎死亡人数最多,为87922例。病死率最高的是利比里亚,为4.93%。结论:通过对社区大多数年龄组进行疫苗接种并保持社会距离,预防COVID-19传播是可能的。升级诊断设备,识别健康和隔离的携带者,也能有效减少COVID- 19的传播。卫生官员和志愿者的合作在更充分地识别患者和执行隔离规则方面是有效的。世界卫生组织为世界各地,特别是非洲的低收入和中等收入国家提供财政支持、诊断设备和疫苗。慈善团体提供财政支持,提供保险服务和医疗和制药设备,是减少COVID- 19损害的有效帮助。
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引用次数: 0
VIM, NDM, IMP, GES, SPM, GIM, SIM Metallobetalactamases in Carbapenem-Resistant Pseudomonas Aeruginosa Isolates from a Turkish University Hospital 土耳其大学医院耐碳青霉烯铜绿假单胞菌分离株中的VIM, NDM, IMP, GES, SPM, GIM, SIM金属β -内酰胺酶
Pub Date : 2022-06-07 DOI: 10.5812/jamm-118712
Y. Tanrıverdi Çaycı, Ilknur Biyik, A. Birinci
Background: Pseudomonas aeruginosa is an important opportunistic pathogen, and carbapenem resistance is an emerging problem. The determination of resistance genes is vital for epidemiological purposes, and the early determination of carbapenemase production methods is also recommended. Objectives: The present study aimed to investigate the presence of VIM, NDM, IMP, GES, SPM, GIM, and SIM genes and study the results of the blue carba test as a phenotypic carbapenamase detection method in P. aeruginosa. Methods: In this study, 200 carbapenem-resistant P. aeruginosa isolates were included. The DNA extraction of the carbapenem-resistant isolates was performed using the boiling method. Following the DNA extraction, optimization was conducted using the original primers. After optimization, the VIM, NDM, IMP, GES, SPM, GIM, and SIM genes were examined using the polymerase chain reaction (PCR) method. Results: The isolates were mainly identified from the tracheal aspirate cultures (34.5%). The PCR method revealed the presence of VIM in one of the P. aeruginosa isolates, and the NDM gene in one isolate using. None of the isolates was positive in terms of the IMP, GES, SPM, GIM, and SIM genes. Conclusions: In our study, two carbapenemase genes (VIM and NDM) were detected in the P. aeruginosa isolates.
背景:铜绿假单胞菌是重要的条件致病菌,碳青霉烯类耐药是一个新兴问题。耐药基因的测定对流行病学研究至关重要,同时也建议早期测定碳青霉烯酶的生产方法。目的:本研究旨在探讨VIM、NDM、IMP、GES、SPM、GIM和SIM基因在铜绿假单胞菌中是否存在,并研究蓝碳水化合物试验作为碳青霉酶表型检测方法的结果。方法:选取200株耐碳青霉烯类铜绿假单胞菌。采用煮沸法提取耐碳青霉烯菌株的DNA。提取DNA后,使用原始引物进行优化。优化后,采用聚合酶链反应(PCR)法检测VIM、NDM、IMP、GES、SPM、GIM和SIM基因。结果:分离株主要来源于气管吸出培养物(34.5%)。PCR方法在铜绿假单胞菌分离株中发现了VIM基因,在铜绿假单胞菌分离株中发现了NDM基因。IMP、GES、SPM、GIM和SIM基因均未检测出阳性。结论:本研究在铜绿假单胞菌分离株中检测到两个碳青霉烯酶基因(VIM和NDM)。
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引用次数: 4
Prevalence of Burnout Syndrome in Medical Assistants Working in Hospitals Affiliated with Urmia University of Medical Sciences 乌尔米娅医科大学附属医院医务助理职业倦怠的患病率
Pub Date : 2022-05-30 DOI: 10.5812/jamm-118827
Peyman Atabaki, O. Garkaz, S. Paryab, S. Hamednia, Somayeh Mehmanfar, H. Mehryar
Background: Stress and strain are an inevitable part of a professional life and originate from work-related experiences. Since the residents are highly exposed to burnout aroused by physical, psychological, and emotional stress, this study aimed to investigate the frequency of burnout syndrome in medical assistants working in hospitals affiliated with the Urmia University of Medical Sciences. Methods: This descriptive cross-sectional study examined all residents working in the hospital affiliated with the Urmia University of Medical Sciences using the census method. Two demographic and burnout questionnaires were distributed to collect the required information. Data were collected and imported to SPSS software version 20 and then analyzed using descriptive statistics. Results: In this study, the results showed that out of 147 assistants in the study, 78 (53.1%) were male and 69 (46.9%) were female, and 104 (70.7%) were married. The mean score of the questions was 34.66 ± 13. The mean score of burnout was 51.53 ± 11.15 among the male residents and 53.61 ± 11.74 among the female residents. The burnout score was 51.82 ± 11.29 among the married assistants and 54.19 ± 11.77 among the single assistants. Moreover, There was no relationship between gender and burnout score (P = 0.275) and between marriage and burnout score (P = 0.26). Conclusions: In this study, the results indicate that most residents suffer from burnout symptoms; hence, appropriate measures and planning are required to detect and eliminate the causes of burnout.
背景:压力和紧张是职业生活中不可避免的一部分,源于与工作相关的经历。鉴于住院医师在身体、心理和情绪压力下极易产生职业倦怠,本研究旨在调查乌尔米娅医科大学附属医院医务助理职业倦怠的发生频率。方法:采用人口普查方法,对乌尔米娅医科大学附属医院的所有住院医师进行描述性横断面研究。发放两份人口统计和职业倦怠问卷,收集所需信息。数据收集后导入SPSS软件20版,采用描述性统计进行分析。结果:本研究结果显示,参与研究的147名助理中,男性78人(53.1%),女性69人(46.9%),已婚104人(70.7%)。问卷平均得分为34.66±13分。男性住院医师的平均倦怠分为51.53±11.15分,女性住院医师的平均倦怠分为53.61±11.74分。已婚助理的职业倦怠得分为51.82±11.29,单身助理的职业倦怠得分为54.19±11.77。性别与倦怠得分无显著相关(P = 0.275),婚姻与倦怠得分无显著相关(P = 0.26)。结论:本研究结果显示,大部分住院医师存在倦怠症状;因此,需要适当的措施和计划来发现和消除职业倦怠的原因。
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引用次数: 0
Evaluating the Quality of Work Life Among Nurses: A Systematic Review 评价护士工作生活质量:一项系统综述
Pub Date : 2022-05-24 DOI: 10.5812/jamm-118471
A. Ebadi, Z. Tabanejad
Introduction: Quality of work life among nurses can affect organizational productivity and quality of care. This study aimed to review the outcome of research conducted in this field. Methods: In this study, five major databases, including Google Scholar, PubMed, ScienceDirect, Scopus, and Web of Science were searched for relevant papers published between 2000 and October 2020 using the following keywords: ‘nurse’, ‘nursing work life’, ‘quality of work life’, ‘nurses' quality of work life’, and ‘scale’. Finally, ten relevant studies were included in the study and the tools introduced in the selected articles were assessed according to the COSMIN checklist. Results: Out of 298 retrieved articles, nine related studies were analyzed based on the COSMIN checklist. None of these tools had all the features listed in COSMIN checklist. However, all tools had acceptable internal consistency and construct validity. Conclusions: Designing a valid and special tool to measure the quality of work life among the nurses is necessary to improve the quality of mental and physical conditions, prevent leaving the nursing job, increase motivation and willingness to work as a nurse, and increase productivity for nurses and organizations.
导言:护士的工作生活质量会影响组织的生产力和护理质量。本研究旨在回顾这一领域的研究成果。方法:本研究以“护士”、“护理工作生活”、“工作生活质量”、“护士工作生活质量”和“规模”为关键词,在Google Scholar、PubMed、ScienceDirect、Scopus和Web of Science五大数据库中检索2000年至2020年10月期间发表的相关论文。最后,将10项相关研究纳入本研究,并根据COSMIN清单对所选文章中引入的工具进行评估。结果:在298篇检索文章中,根据COSMIN核对表分析了9篇相关研究。这些工具都没有COSMIN清单中列出的所有功能。然而,所有工具都具有可接受的内部一致性和结构效度。结论:设计一种有效的、专用的测量护士工作生活质量的工具,对于改善护士的精神和身体状况质量,防止护士离开护理岗位,提高护士工作的积极性和意愿,提高护士和组织的工作效率是必要的。
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引用次数: 2
Prevalence of Dyslipidemia in Military Police Officers Operating in a Special Operations Group 特种作战部队宪兵血脂异常的流行情况
Pub Date : 2022-04-18 DOI: 10.5812/jamm-116360
Thomaz Talarico Neto, Higino Carlos Hahns Júnior, M. Minelli, José Mauricio Magraner Paixão dos Santos, Marcos Corrêa Junior, Y. Bella, Cesar Baraldi Gonella, Leandro Ferreira, Fernanda Galante, Carlos Eduardo Martinelli Júnior, H. Tourinho Filho
Background: Dyslipidemia is a disorder caused by alterations in the plasma concentrations of one or more lipids/lipoproteins. It is considered a metabolic disease that exposes the body to various harmful and even fatal events, one of which is the increased risk for cardiovascular diseases. Military police officers, in turn, are exposed to high physical and psychological risks and may suffer from cardiovascular diseases more than other professions. Objectives: In this sense, the objective of the present study was to evaluate the lipid profile of military police officers working in a special operations group to identify the prevalence of dyslipidemia among the subjects. Methods: In total, 65 volunteers participated in the study, members of a special operations battalion (37.26 ± 5.77 years of age). Blood collection was performed after 12 hours of fasting to analyze the following variables: Total cholesterol, triglycerides, LDL-c, and HDL-c. Results: The total cholesterol value presented the highest variation, since 77% of those evaluated showed altered values. Regarding the values of HLD, LDL, and triglycerides, most subjects (89%, 72%, and 80%, respectively) presented results within normal values Conclusions: It can be concluded that most participants presented regular values for most of the analyzed lipid fractions, which could contribute to their demands during their work activities. It is believed that the positive results seen in this group, which is heterogeneous with respect to age, are due to an extremely rigorous selection process and a training program that elevates the individuals to the rank of elite soldiers within the Brazilian military police.
背景:血脂异常是一种由一种或多种血脂/脂蛋白的血浆浓度改变引起的疾病。它被认为是一种代谢疾病,使身体暴露于各种有害甚至致命的事件中,其中之一就是心血管疾病的风险增加。反过来,军事警察面临着很高的身体和心理风险,可能比其他职业更容易患心血管疾病。目的:从这个意义上说,本研究的目的是评估在特种作战组工作的宪兵军官的血脂状况,以确定受试者中血脂异常的患病率。方法:某特种作战营65名志愿者(37.26±5.77岁)参与研究。禁食12小时后采血,分析以下变量:总胆固醇、甘油三酯、LDL-c和HDL-c。结果:总胆固醇值表现出最大的变化,因为77%的评估显示改变值。在HLD、LDL和甘油三酯方面,大多数受试者(分别为89%、72%和80%)的结果在正常值范围内。结论:大多数受试者对所分析的大多数脂质组分的值都是正常的,这可能有助于他们在工作活动中的需求。据信,在这个年龄不同的群体中看到的积极结果是由于极其严格的选拔过程和将个人提升到巴西宪兵精英级别的培训计划。
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引用次数: 0
The Effect of Strenuous Endurance Training in Combination with Zingiber Supplementation on Serum Interleukin-17 and Skeletal Muscle Total Oxidant in Male Rats 高强度耐力训练联合补充生姜对雄性大鼠血清白细胞介素-17和骨骼肌总氧化剂的影响
Pub Date : 2022-04-03 DOI: 10.5812/jamm.115175
Mozhgan Usefpour, A. Ghasemnian, A. Rahmani
Background: This study aimed to investigate the effect of 8 weeks of strenuous endurance training (ET) with ginger extract supplementation on resting levels of serum interleukin-17 (IL-17) and total antioxidant capacity (TAC) of muscle in male Wistar rats. Methods: Forty rats were divided randomly into five groups: control (n = 8), Sham (n = 8), zingier (n = 8), ET (n = 8), and ET + zingiber (n = 8). The training protocols consisted of ET on a treadmill for 8 weeks (5 days a week). Ginger extract (100 g/kg body weight) was injected subcutaneously in the ginger group and ET + zingiber group for 8 weeks (3 days a week) from the beginning of the second week. Forty-eight hours after the last training session and 4 hours of overnight fasting, blood and tissue samples were collected. The serum concentration of IL-17 was measured using the ELISA method by BT kit, China. TAC concentration of muscle tissue was measured using the colorimetric method with ZELBIO kits, Germany. One-way analysis of variance (ANOVA) and Scheffe’ post hoc tests were used to analyze the data. Results: This study showed that after 8 weeks, serum levels of IL-17 were significantly higher in the ET groups than in the control group (P < 0.05). Also, serum IL-17 was significantly decreased in the ET + ginger group than the endurance group (P < 0.05). However, there was no significant difference in TAC of muscle tissue in the ET, ginger, and ET + ginger groups than the control group (P < 0.05). Conclusions: This study demonstrated that 8 weeks of endurance training, combined with ginger supplementation, significantly reduced the inflammatory marker of IL-17. Therefore, ginger supplementation with endurance training seems to have a protective role against oxidative and inflammatory factors.
背景:本研究旨在探讨8周高强度耐力训练(ET)加生姜提取物对雄性Wistar大鼠静息时血清白细胞介素-17 (IL-17)水平和肌肉总抗氧化能力(TAC)的影响。方法:40只大鼠随机分为5组:对照组(n = 8)、假手术组(n = 8)、zingier组(n = 8)、ET组(n = 8)和ET + zingiber组(n = 8)。训练方案为在跑步机上进行ET训练,为期8周(每周5天)。从第二周开始,生姜组和ET +生姜组皮下注射生姜提取物100 g/kg体重,连续8周(每周3天)。最后一次训练后48小时和禁食4小时,采集血液和组织样本。血清IL-17浓度测定采用ELISA法,采用中国BT试剂盒。采用德国ZELBIO试剂盒比色法测定肌肉组织的TAC浓度。采用单因素方差分析(ANOVA)和Scheffe事后检验对数据进行分析。结果:本研究显示,8周后,ET组血清IL-17水平显著高于对照组(P < 0.05)。ET +生姜组血清IL-17显著低于耐力组(P < 0.05)。而ET组、生姜组和ET +生姜组肌肉组织TAC与对照组相比差异不显著(P < 0.05)。结论:本研究表明,8周的耐力训练,结合生姜补充,显著降低炎症标志物IL-17。因此,生姜补充耐力训练似乎具有抗氧化和炎症因素的保护作用。
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引用次数: 0
The Seroprevalence of Toxoplasma Gondii and Associated Risk Factors Among Type 1 Diabetes Mellitus Patients in Abadan, Southwest Iran 伊朗西南部阿巴丹 1 型糖尿病患者弓形虫血清阳性率及相关风险因素
Pub Date : 2022-03-14 DOI: 10.5812/jamm.117842
Shahrzad Soltani, Sanaz Tavakoli, M. Sabaghan, Mehdi Sagha Kahvaz, Marzieh Pashmforosh, M. Foroutan
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引用次数: 1
Design of Comprehensive System for Screening, Diagnosis, and Treatment of Breast Cancer in Armed Forces 军队乳腺癌筛查、诊断和治疗综合系统的设计
Pub Date : 2022-01-24 DOI: 10.5812/jamm.120371
Mohammad Hadi Bahri, M. Ariana, A. Khoshdel, A. Naseri
Context: In the present study, we aimed to design a comprehensive system for screening, diagnosing, and treating breast cancer in the armed forces. Methods: We conducted a focused group meeting (FGM) and article review to evaluate one-stop clinics. Review studies with a standard design based on the PRISMA guidelines and the “Cochrane Handbook” to conduct data analysis were reviewed in the article review phase. In addition, for data extraction in the initial phase, the text of each session with specialists was read and discussed to get the general atmosphere of the meetings. Results: In the present study, we observed the importance of better diagnosis and treatment of army cases, as mentioned in previous studies. Thus, we should use one-stop clinics to screen, diagnose, and treat army cases with breast cancer. In the present study, we designed this system and reviewed the best results in screening, diagnosis, and treatment of breast cancer in army cases. Conclusions: A general and regular one-stop clinic dedicated to rapid diagnosis in a comprehensive cancer center can be a highly effective model of care, although not directly linked to screening structures.
背景:在本研究中,我们旨在设计一个全面的系统来筛查、诊断和治疗军队中的乳腺癌。方法:我们通过焦点小组会议(FGM)和文献回顾来评价一站式诊所。采用基于PRISMA指南和《Cochrane手册》进行数据分析的标准设计的综述研究在文章综述阶段进行综述。此外,为了在初始阶段提取数据,将阅读和讨论每届专家会议的案文,以了解会议的一般气氛。结果:在本研究中,我们观察到更好的诊断和治疗军队病例的重要性,正如以往的研究所提到的。因此,我们应该使用一站式诊所来筛查、诊断和治疗军队乳腺癌病例。在本研究中,我们设计了这个系统,并回顾了军队病例中乳腺癌的筛查、诊断和治疗的最佳结果。结论:在综合性癌症中心,尽管与筛查结构没有直接联系,但致力于快速诊断的综合和定期一站式诊所可能是一种非常有效的护理模式。
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引用次数: 0
Anti-Toxoplasma Activity of Tellurium Oxide (TeO2) Nanoparticle on Toxoplasma gondii In vitro 氧化碲纳米颗粒体外抗刚地弓形虫活性研究
Pub Date : 2022-01-18 DOI: 10.5812/jamm.115282
Amir KarimiPourSaryazdi, F. Ghaffarifar, M. Barati, Roya Omidi
Background: Toxoplasma gondii is an obligate intracellular parasite in humans and many warm-blooded animals worldwide. Objectives: This study aimed to investigate the different antiparasitic effects of tellurium oxide (TeO2) nanoparticles against T. gondii. Methods: In this study, we used tachyzoite assay (ocular counting test) to determine the lethal effect of tellurium nanoparticles on parasites. Toxic effects of nanoparticles on macrophages were also evaluated using MTT assay. The type of parasitic cell death (necrosis or apoptosis) was determined by flow cytometric analysis. Results: According to the examination of the parasites by light microscopy, TeO2 nanoparticles had destructive and lethal effects on T. gondii. The results of the MTT assay showed that the toxic effects on macrophages were more significant at high concentrations (400 μg/mL). Flow cytometric analysis also estimated the percentage of apoptosis (primary and secondary) of the parasites at 56.97%. Conclusions: According to the findings, tellurium Oxide nanoparticles have a toxic effect on T. gondii and lead to apoptosis in this parasite. This research boosts different tests in another parasite.
背景:刚地弓形虫是一种专性细胞内寄生虫,存在于人类和许多温血动物体内。目的:研究氧化碲(TeO2)纳米颗粒对弓形虫的不同抗寄生作用。方法:采用速殖子法(眼计数法)测定纳米碲对寄生虫的杀伤作用。采用MTT法评价纳米颗粒对巨噬细胞的毒性作用。通过流式细胞术分析确定寄生细胞死亡类型(坏死或凋亡)。结果:光镜下观察,纳米TeO2对弓形虫具有一定的杀伤和致死作用。MTT实验结果显示,高浓度(400 μg/mL)对巨噬细胞的毒性作用更为显著。流式细胞分析还估计,寄生虫的细胞凋亡(原发性和继发性)百分比为56.97%。结论:氧化碲纳米颗粒对弓形虫具有毒性作用,可导致弓形虫细胞凋亡。这项研究促进了对另一种寄生虫的不同测试。
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引用次数: 2
期刊
Journal of Archives in Military Medicine
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