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Stomach Cancer in Patients Referred to Tohid Hospital in Sanandaj, 2012 - 2018: An Epidemiological Study 2012 - 2018年在Sanandaj Tohid医院转诊的胃癌患者的流行病学研究
Pub Date : 2021-03-31 DOI: 10.5812/JAMM.111506
Mastore Rahimi, G. Roshanaei, J. Faradmal, Bayazid Ghaderi, L. Moradi
Background: Stomach cancer is the fourth most common cancer in the world and first cancer in Iran. The northern and northwestern regions of the country are areas with a high prevalence of gastrointestinal cancers, especially gastric cancer. Different factors are effective in the incidence of this cancer. Objectives: The present study aimed to evaluate the epidemiology of gastric cancer. Methods: This research was a cross-sectional study. All patients referred to Tohid Hospital in Sanandaj between 2012 and 2018 were examined. Data were extracted using patients' medical records. Descriptive information was collected through SPSS software, and the results were analyzed. Results: The number of patients in this study was 553. The mean age was 66.9 years, and the highest age group was 60 - 80 years. Four hundred twelve patients were male, and 141 were female. In 50% of patients, the location of the cardiac tumor was gastric. Chemotherapy was the most common treatment in more than 60% of patients. Conclusions: The results of this study show that smoking is unfortunately high in patients in this province. An educational intervention to quit smoking is recommended. Smoking is an important risk factor for gastric cancer, and this intervention may also be effective in reducing the incidence of this disease.
背景:胃癌是世界上第四大最常见的癌症,也是伊朗的第一大癌症。我国的北部和西北部地区是胃肠道癌症,特别是胃癌的高发地区。不同的因素对这种癌症的发生有影响。目的:探讨胃癌的流行病学。方法:本研究为横断面研究。2012年至2018年期间,所有转诊到萨南达杰Tohid医院的患者都接受了检查。从患者的医疗记录中提取数据。通过SPSS软件收集描述性信息,并对结果进行分析。结果:本组患者553例。平均年龄66.9岁,最高年龄组为60 ~ 80岁。其中男性112例,女性141例。50%的患者心脏肿瘤位于胃。化疗是60%以上患者最常用的治疗方法。结论:本研究的结果表明,不幸的是,该省患者的吸烟率很高。建议进行戒烟教育干预。吸烟是胃癌的重要危险因素,这种干预也可能有效降低胃癌的发病率。
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引用次数: 0
A Review of Management Methods and Modern Treatments for Chemical Wounds 化学伤口的管理方法和现代疗法综述
Pub Date : 2021-03-31 DOI: 10.5812/JAMM.112029
H. A. Ashtiani, Amirreza Noori Garmroodi, E. Hazrati
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引用次数: 0
Reverse Transcription Polymerase Chain Reaction (RT-PCR) as a Tool for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Surveillance in the Military 逆转录聚合酶链反应(RT-PCR)作为军队监测严重急性呼吸综合征冠状病毒-2 (SARS-CoV-2)的工具
Pub Date : 2021-03-31 DOI: 10.5812/JAMM.111603
Idris Zubairu Sadiq
Context: Military organizations like civilian communities are under considerable threat due to COVID-19 and other re-emerging infectious diseases, which may impair their operations and training. The aim of this review was to discuss the application of RT-PCR technology for detecting and surveillance of SARS-CoV-2 among armed forces to successfully halt COVID-19 transmission. Evidence Acquisition: Relevant literature was collected from PubMed, Science Direct, and Google Scholar Results: By combining both detection and quantification of pathogens, RT-PCR provides a reliable and sensitive method for detecting SARS-CoV-2 via targeting the viral ORF1ab, E, and N genes. Military surveillance plays an important role in the early detection and identification of positive cases, isolating infected patients, contact tracing, and quarantine to contain the spread of the disease among personnel. This technology emerges as a suitable tool for disease surveillance in the military and early detection and control of diseases. Conclusions: The COVID-19 disease has spread into different parts of the world and may affect military training and operations. So, there is a need for active disease surveillance and preparedness plans in the military. Accordingly, RT-PCR, as a standard tool for SARS-CoV-2 detection, can be used for the surveillance and monitoring of military personnel to successfully curtail COVID-19.
背景:由于COVID-19和其他重新出现的传染病,军事组织如平民社区面临相当大的威胁,这可能会影响其行动和训练。本综述旨在探讨RT-PCR技术在部队中检测和监测SARS-CoV-2的应用,以成功阻止COVID-19的传播。证据获取:从PubMed、Science Direct和Google Scholar收集相关文献。结果:RT-PCR结合病原体检测和定量,通过靶向病毒ORF1ab、E和N基因,为检测SARS-CoV-2提供了一种可靠、敏感的方法。军事监测在早期发现和识别阳性病例、隔离感染患者、追踪接触者和隔离以遏制疾病在人员中的传播方面发挥着重要作用。这项技术成为军队疾病监测和疾病早期发现和控制的合适工具。结论:新冠肺炎疫情已扩散至世界各地,可能影响军事训练和作战。因此,军队需要积极的疾病监测和准备计划。因此,RT-PCR作为SARS-CoV-2检测的标准工具,可以用于军事人员的监测和监测,从而成功遏制COVID-19。
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引用次数: 1
Effects of Vitamin D Supplementation on Inflammatory Markers in Multiple Sclerosis Patients: A Systematic Review and Meta-analysis 补充维生素D对多发性硬化症患者炎症标志物的影响:系统回顾和荟萃分析
Pub Date : 2021-03-31 DOI: 10.5812/JAMM.112426
S. Mehrabadi, E. Zahedi
Context: Numerous studies have indicated that vitamin D can modulate the immune system and plays an important role in regulating immune cells’ functions. Some clinical studies have assessed the effect of vitamin D supplementation on cytokine markers in multiple sclerosis (MS) as a disease in which the immune system’s function is disrupted. Evidence Acquisition: This study was designed to assess randomized clinical trial studies evaluating the overall effect of vitamin D on the levels of IL-10, IL-17, and IFN-γ in MS patients. Methods: We searched PubMed and Scopus online databases up to November 2020 for relevant randomized clinical trial studies by using certain keywords. Eight studies from 273 articles, with a total sample of 443 participants, were considered Results: The meta-analysis indicated that vitamin D consumption did not significantly change the levels of IL-10 (WMD : -174.56, 95% CI: -373.10 to 23.98), IL-17 (WMD : -0.11, 95% CI: -0.54.10 to 0.33), or IFN-γ (WMD : 61.47, 95% CI: 43.96 to 78.98) in MS patients. Conclusions: Further clinical trials are warranted to evaluate the effects of vitamin D supplement on IL-10 and IL-17, and INFγ levels in MS patients.
背景:大量研究表明,维生素D可以调节免疫系统,在调节免疫细胞功能方面发挥重要作用。一些临床研究评估了补充维生素D对多发性硬化症(MS)中细胞因子标志物的影响,多发性硬化症是一种免疫系统功能被破坏的疾病。证据获取:本研究旨在评估随机临床试验研究,评估维生素D对MS患者IL-10、IL-17和IFN-γ水平的总体影响。方法:检索PubMed和Scopus在线数据库,检索截止到2020年11月的相关随机临床试验研究。结果:荟萃分析表明,维生素D摄入并没有显著改变MS患者IL-10 (WMD: -174.56, 95% CI: -373.10至23.98)、IL-17 (WMD: -0.11, 95% CI: -0.54.10至0.33)或IFN-γ (WMD: 61.47, 95% CI: 43.96至78.98)的水平。结论:需要进一步的临床试验来评估补充维生素D对MS患者IL-10、IL-17和INFγ水平的影响。
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引用次数: 0
Comparison of Different Approaches in Estimating Initial Reproduction Number of SARS-CoV-2 in the Islamic Republic of Iran 不同估算方法在伊朗伊斯兰共和国SARS-CoV-2初始繁殖数的比较
Pub Date : 2020-12-31 DOI: 10.5812/JAMM.113224
Nasrin Talkhi, N. Esmaeilzadeh, M. Shakeri, Zahra Pasdar
Background: The basic reproduction number (R0) is an epidemic threshold parameter that indicates the magnitude of disease transmission and thus allows suggestions for the planning of control measures. Objectives: Our aim in this study was to compare different approaches for estimating R0 in the early stage of the SARS-CoV-2 outbreak and discern the best-fitting model. Methods: The dataset was derived from cumulative laboratory-confirmed COVID-19 cases from 26th February to 30th May 2020 in Iran. The methods of exponential growth (EG) rate, maximum likelihood (ML), time-dependent (TD) reproduction number, attack rate (AR), and sequential Bayesian (SB) model were used. The gamma distribution (mean 4.41 ± 3.17 days) was used for serial interval (SI) distribution. The best-fitting method was selected according to the lowest root mean square error (RMSE). Results: We obtained the following estimated R0 [95% confidence interval]: 1.55 [1.54; 1.55], 1.46 [1.45; 1.46], 1.31 [1.30; 1.32], and 1.40 [1.39; 1.41] using EG, ML, TD, and SB methods, respectively. Additionally, the EG and ML methods showed an overestimation of R0, and the SB method showed to be under-fitting in the estimation of R0. The AR method estimated R0 equal to one. The TD method had the lowest RMSE. Conclusions: The simulated and actual R0 of TD showed that this method had a good fit for actual data and the lowest RMSE. Therefore, the TD method is the most appropriate method with the best performance in estimating actual R0 values.
背景:基本繁殖数(R0)是表明疾病传播程度的流行阈值参数,可为规划控制措施提供建议。目的:本研究的目的是比较在SARS-CoV-2爆发早期估计R0的不同方法,并找出最合适的模型。方法:该数据集来自伊朗2020年2月26日至5月30日累计实验室确诊的COVID-19病例。采用指数增长(EG)率、最大似然(ML)、时间依赖(TD)繁殖数、攻击率(AR)和顺序贝叶斯(SB)模型等方法。连续间隔(SI)分布采用gamma分布(平均4.41±3.17天)。根据最小均方根误差(RMSE)选择最佳拟合方法。结果:我们得到的估计R0[95%置信区间]:1.55 [1.54;1.55], 1.46 [1.45;1.46], 1.31 [1.30;1.32], 1.40 [1.39;1.41]分别采用EG、ML、TD和SB方法。此外,EG和ML方法对R0的估计过高,而SB方法对R0的估计欠拟合。AR法估计R0等于1。TD方法的均方根误差最低。结论:TD的模拟R0和实际R0表明,该方法与实际数据拟合良好,RMSE最低。因此,在估计实际R0值时,TD方法是最合适的方法,性能最好。
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引用次数: 0
Vaccination in the Yugoslav National Army: A Significant Risk Factor for Acquiring Chronic Hepatitis B Virus Infection During Army Service in the Former Yugoslavia 南斯拉夫国民军的疫苗接种:前南斯拉夫军队服役期间获得慢性乙型肝炎病毒感染的重要危险因素
Pub Date : 2020-12-31 DOI: 10.5812/JAMM.111950
N. Kmet, M. Poljak, M. Rajter, Tanja Selič, Z. Baklan, E. Pal, M. Maticic
Background: To prevent the spread of infectious diseases, several state armies implemented obligatory vaccination programs also practiced in the former Yugoslav National Army (YNA). Iatrogenic hepatitis B virus (HBV) transmissions during vaccinations in the armies were well documented, but to the best of our knowledge, no such study has been performed in the former Yugoslavia. Objectives: In the present study, we determined risk factors for acquiring chronic hepatitis B (CHB) infection in patients in Slovenia. This study focused on the detection of a statistically significant risk factor in males, namely “vaccination in the YNA”. Methods: One thousand seven hundred and twenty-nine patients from all Slovenian regions who tested positive for HBV surface antigen (HBsAg) at the national referential laboratory for viral hepatitis diagnostics between January 1997 and December 2010 were included retrospectively. Accordingly, demographic, epidemiological, virological, and clinical data were extracted from the medical documentation and were statistically analyzed. Results: For 1,122 (64.9%) out of 1,729 patients, data regarding risk factors for acquiring HBV infection were available. The risk factor for infection of almost 60% of HBV chronically infected individuals with available data, followed by “HBV infection in the family” (19.8%) and “blood/blood products transfusion before the nineties” (8%) was unknown. Seven males (0.6%) (mean age ± SD, 53.7 ± 4.50 years) reported “vaccination in the YNA” as a risk factor for acquiring chronic HBV infection. “Vaccination in the YNA” was a significant risk factor for CHB infection in men over 46 years of age (P = 0.006). Conclusions: A significant risk factor for infection in Slovenian men over 46 years of age was identified as “vaccination in the YNA”, which is specific to this geographic region and, to the best of our knowledge, has not been previously described in the peer-reviewed literature.
背景:为了防止传染病的传播,一些国家军队实施了强制性疫苗接种计划,前南斯拉夫国民军(YNA)也实行了这种计划。在军队接种疫苗期间,医源性乙型肝炎病毒(HBV)的传播有充分的记录,但据我们所知,在前南斯拉夫没有进行过这样的研究。目的:在目前的研究中,我们确定了斯洛文尼亚患者获得慢性乙型肝炎(CHB)感染的危险因素。本研究的重点是在男性中发现一个具有统计学意义的危险因素,即“在YNA接种疫苗”。方法:回顾性纳入1997年1月至2010年12月在病毒性肝炎诊断国家参考实验室检测HBV表面抗原(HBsAg)阳性的来自斯洛文尼亚所有地区的1229例患者。因此,从医学文献中提取人口学、流行病学、病毒学和临床资料,并进行统计分析。结果:在1729例患者中,有1122例(64.9%)患者获得了有关HBV感染危险因素的数据。在现有数据中,近60%的HBV慢性感染者感染的危险因素未知,其次是“家庭中HBV感染”(19.8%)和“90年代以前输血/血液制品”(8%)。7名男性(0.6%)(平均年龄±SD, 53.7±4.50岁)报告“在YNA接种疫苗”是获得慢性HBV感染的危险因素。“在YNA接种疫苗”是46岁以上男性CHB感染的重要危险因素(P = 0.006)。结论:斯洛文尼亚46岁以上男性感染的一个重要危险因素被确定为“YNA疫苗接种”,这是该地理区域特有的,据我们所知,以前在同行评议的文献中没有描述过。
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引用次数: 1
Security in Cyberspace in the Field of International Relations 国际关系领域的网络空间安全
Pub Date : 2020-12-31 DOI: 10.5812/JAMM.114485
M. Abbasi
: As cyberspace expands and globalizes, we are experiencing a new layer of threats to governments in the form of cyber threats that have impacted various facets of national security, including social, economic, military, and political security. As a result, in the form of electronic warfare, it has developed a new kind of war and conflict. Therefore, it has impacted international security, necessitating solutions to minimize the harm caused by this form of threat and preserve international security. So, network security has brought to light some of the underlying tensions between international rivalry and cybersecurity cooperation. Thus, the current study employs a descriptive-analytical method to investigate and analyze the role of international organizations, especially the Organization for Economic Cooperation and Development, in the development of cyberspace security. The hypothesis raised in this study is that since governments are increasingly relying on unilateral policies and resources to ensure cyber protection, international organizations should play an active role in shaping cooperation among their members in the form of approaches focused on international cooperation on cybersecurity and the prevention of cyber threats, as well as the development of a global cybersecurity system.
随着网络空间的扩张和全球化,我们正经历着对政府的新一层威胁,这些威胁以网络威胁的形式影响着国家安全的各个方面,包括社会、经济、军事和政治安全。因此,以电子战的形式,发展了一种新型的战争和冲突。因此,它影响到国际安全,需要解决办法,以尽量减少这种形式的威胁造成的损害,维护国际安全。因此,网络安全暴露了国际竞争与网络安全合作之间的一些潜在紧张关系。因此,本研究采用描述性分析方法来调查和分析国际组织,特别是经济合作与发展组织在网络空间安全发展中的作用。本研究提出的假设是,由于各国政府越来越依赖单方面的政策和资源来确保网络保护,国际组织应在塑造其成员之间的合作方面发挥积极作用,其形式是侧重于网络安全和预防网络威胁的国际合作,以及全球网络安全体系的发展。
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引用次数: 0
Establishment of a Monitoring Clinic Based on Wearables for Patients with Heart Failure 为心力衰竭患者建立基于可穿戴设备的监测诊所
Pub Date : 2020-11-16 DOI: 10.5812/jamm.110456
S. Yarahmadi, Mohammad Gholami, Tayebeh Cheraghian
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引用次数: 0
Profile of Steroid Hormones and sex Hormone-Binding Globulin of Elite Soldiers 精锐士兵类固醇激素及性激素结合球蛋白的研究
Pub Date : 2020-11-01 DOI: 10.5812/jamm.110360
Thomaz Talarico Neto, Higino Carlos Hahns Júnior, M. Minelli, José Mauricio Magraner Paixão dos Santos, Marcos Corrêa Junior, Y. Bella, Fernanda Galante, Cesar Baraldi Gonella, Leandro Ferreira, Carlos Eduardo Martinelli Júnior, H. Tourinho Filho
Background: Military police training should characterize the necessary abilities to conduct their activities with excellence. Biochemical parameters have a significant role in the performance of individuals and, therefore, are of crucial importance when trying to improve the teamwork of police officers, particularly for special operations groups. Hence, the use of laboratory analysis in activities that cause great physiological stress is of paramount importance. Objectives: The present study aimed to evaluate the profile of steroid hormones and the sex hormone-binding-globulin of soldiers belonging to a special operations force. Methods: In this cross-sectional study, blood samples of 75 volunteers collected after 12 hours of fasting are analyzed. Data were analyzed using descriptive statistics (i.e., mean and standard deviation) and compared to the reference values for each biomarker, referencing each individual in their age group. Results: Most of the participants presented adequate concentrations for their respective ages in relation to the data analyzed. Even the inclusion of individuals from different age groups did not change the good results found in the group. Conclusions: The positive results found in such a heterogeneous group with respect to age group can be attributed to an extremely rigorous selection process and a training program that elevates them to the rank of elite soldiers of the military police.
背景:宪兵训练应具有出色开展活动的必要能力。生化参数在个人的表现中起着重要作用,因此,在试图提高警察的团队合作时,特别是对特殊行动小组来说,生化参数至关重要。因此,在引起巨大生理应激的活动中使用实验室分析是至关重要的。目的:了解某特种作战部队士兵的类固醇激素和性激素结合球蛋白水平。方法:在这项横断面研究中,对75名志愿者在禁食12小时后采集的血液样本进行分析。使用描述性统计(即平均值和标准差)对数据进行分析,并将其与每个生物标志物的参考值进行比较,参考其年龄组中的每个个体。结果:与所分析的数据相关,大多数参与者的浓度适合他们各自的年龄。即使包括来自不同年龄段的个体,也没有改变该组中发现的良好结果。结论:在这样一个不同年龄段的异质群体中发现的积极结果可归因于极其严格的选拔过程和将他们提升为宪兵精英士兵的训练计划。
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引用次数: 0
Prevalence of Psychiatric Disorders in Patients Referring to a Psychiatric Clinic in Lorestan Province, West of Iran 伊朗西部洛雷斯坦省精神科门诊患者精神障碍患病率调查
Pub Date : 2020-10-28 DOI: 10.5812/jamm.108729
H. Nazari, M. Saki, S. Yarahmadi, Zoherh Mohammadi
Background: Psychiatric disorders are common and impose a huge burden globally. The study aimed to examine the prevalence of psychiatric disorders in patients referring to a psychiatric clinic in Lorestan. Objectives: This study aimed to investigate the prevalence of psychiatric disorders in patients referring to a psychiatric clinic in Lorestan province Methods: A cross-sectional study was conducted with all people aged 18 years or older. Participants were selected by a convenience sampling method. Diagnostic interviews based on DSM-5 were held for 750 patients who were administered between January and June 2018. The collected data were analyzed by SPSS version 22 using absolute frequency, relative frequency, mean, and chi-square test. Results: Women included 53% of the study sample. The most prevalent psychiatric disorders were anxiety (35.3%) and mood disorders (31.5%). Depression was the most prevalent mood disorder (63.6%), followed by generalized anxiety disorder (60%). The prevalence of psychiatric disorders was higher in people aged 21-30 (28.5%), the illiterate or primary education group (52.4%), housekeepers (29.5%), and married ones (51.8%). Conclusions: The majority of the patients referring to the psychiatric clinic suffered from mood and anxiety disorders. Therefore, public health authorities of the province need to take steps to warrant necessary measures, including mental health promotion policies, to improve the mental health status and prevent anxiety and mood disorders.
背景:精神疾病很常见,在全球范围内造成了巨大的负担。这项研究的目的是检查在Lorestan精神病诊所就诊的患者中精神疾病的患病率。目的:本研究旨在调查在Lorestan省精神病诊所就诊的患者中精神障碍的患病率。方法:对所有18岁及以上的患者进行横断面研究。研究对象采用方便抽样法进行选择。在2018年1月至6月期间,对750名患者进行了基于DSM-5的诊断访谈。收集的数据采用SPSS version 22进行绝对频率、相对频率、均值和卡方检验。结果:女性占研究样本的53%。最常见的精神障碍是焦虑(35.3%)和心境障碍(31.5%)。抑郁症是最常见的情绪障碍(63.6%),其次是广泛性焦虑症(60%)。精神障碍患病率在21-30岁人群(28.5%)、文盲或小学教育人群(52.4%)、家庭主妇(29.5%)和已婚人群(51.8%)中较高。结论:精神科门诊就诊的大部分患者存在情绪和焦虑障碍。因此,该省的公共卫生当局需要采取措施,确保必要的措施,包括促进心理健康的政策,以改善心理健康状况,预防焦虑和情绪障碍。
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引用次数: 0
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Journal of Archives in Military Medicine
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