Sirous Azizi, Z. Rezasoltani, E. Shirzadi, A. Dadarkhah, M. Elahi
Background: Patellofemoral Pain Syndrome (PFPS) is one of the most common diagnoses made for patients referred to physical/rehabilitation and orthopedic clinics. The most common symptom of PFPS is a diffuse pain in front of either one or both knees exacerbated by intense activity, kneeling, squatting, climbing, and weakness of quadriceps muscle. Lumbosacral manipulation and knee exercises are the most commonly used methods in physical medicine with no major side effects. Objectives: The current study aimed to compare the efficacy of the lumbosacral manipulation technique with knee exercises versus sole knee exercises in patients with PFPS. Study Design was Randomized Controlled Clinical Trial. Methods: In this randomized controlled clinical trial, 30 patients (18 females and 12 males) diagnosed with PFPS were divided into two groups of study and control, each with 15 subjects. Those in the intervention group received a single bilateral lumbosacral manipulation after ruling out any contraindication for lumbosacral manipulation by lumbosacral radiography. Quality of life, gait, quadriceps muscle strength, keen pain improvement, and range of motion were evaluated at the beginning and four weeks following the knee strengthening exercises for all participants. Results: The mean age of participants was 34 ± 5 years. The difference between the groups concerning the swing phase of walking and quadriceps muscle strength was in both groups was investigated following providing interventions. Conclusions: The manipulation technique had a greater effect on improving the function of patients with PFPS compared to therapeutic knee exercises.
{"title":"Comparison of the Lumbosacral Manipulation Method Versus Knee Exercises Alone in Patients with Patellofemoral Pain Syndrome","authors":"Sirous Azizi, Z. Rezasoltani, E. Shirzadi, A. Dadarkhah, M. Elahi","doi":"10.5812/jamm.109923","DOIUrl":"https://doi.org/10.5812/jamm.109923","url":null,"abstract":"Background: Patellofemoral Pain Syndrome (PFPS) is one of the most common diagnoses made for patients referred to physical/rehabilitation and orthopedic clinics. The most common symptom of PFPS is a diffuse pain in front of either one or both knees exacerbated by intense activity, kneeling, squatting, climbing, and weakness of quadriceps muscle. Lumbosacral manipulation and knee exercises are the most commonly used methods in physical medicine with no major side effects. Objectives: The current study aimed to compare the efficacy of the lumbosacral manipulation technique with knee exercises versus sole knee exercises in patients with PFPS. Study Design was Randomized Controlled Clinical Trial. Methods: In this randomized controlled clinical trial, 30 patients (18 females and 12 males) diagnosed with PFPS were divided into two groups of study and control, each with 15 subjects. Those in the intervention group received a single bilateral lumbosacral manipulation after ruling out any contraindication for lumbosacral manipulation by lumbosacral radiography. Quality of life, gait, quadriceps muscle strength, keen pain improvement, and range of motion were evaluated at the beginning and four weeks following the knee strengthening exercises for all participants. Results: The mean age of participants was 34 ± 5 years. The difference between the groups concerning the swing phase of walking and quadriceps muscle strength was in both groups was investigated following providing interventions. Conclusions: The manipulation technique had a greater effect on improving the function of patients with PFPS compared to therapeutic knee exercises.","PeriodicalId":15058,"journal":{"name":"Journal of Archives in Military Medicine","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91035546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Koopaie, Mahsan Mosaieby, Zahra Jabbarpour, A. Shamshiri
Background: Photodynamic Therapy (PDT) is considered as one of the alternative treatments for Head and Neck Squamous Cell Carcinoma (HNSCC). P53 mRNA is a tumor suppressor gene whose mutation increases the likelihood of uncontrolled cancer-like divisions. The mutation of CCND1 oncogenic increases the production of cyclin D1 as a tumorigenic protein. Objectives: This study aimed to determine the effect of PDT using toluidine blue as a photosensitizer on the CCND1 and P53 mRNA levels in the HNSCC cell line. Methods: A human HNSCC cell line from NCBI.C196 designation HN5 was used. Cells were divided into four groups: Group I (HNSCC cell line under the influence of toluidine blue and laser irradiation), group II (HNSCC cell line under the influence of toluidine blue), group III (HNSCC cell line under laser irradiation), group IV (control group, HNSCC cell line). A 660 nm THOR laser using toluidine blue as a photosensitizer was applied. The RNA extraction was performed in three steps, including cell degradation, purification, and precipitation by alcohol. The cDNA was prepared using Takara Kit. The Amplicon kit and Real-Time PCR analysis were used for the assessment of mRNA relative levels. Results: The P53 mRNA relative levels were 1.50 ± 0.33 in group I (P = 0.65), 1.49 ± 0.23 (P =0.5) in group II, and 1.40 ± 1.05 (P = 0.63) in group III. Compared to the control group, the mean increases in CCND1 mRNA were 18.01 ± 3.37 (p=0.04) in group I, 17.69 ± 3.3 (P = 0.03) in group II, and 9.01 ± 6.17 (P = 0.20) in group III. Conclusions: The comparison of the fold change index for P53 and CCND1 mRNA by the one-way ANOVA test showed that despite the increased expression of P53 and CCND1 mRNA in treatment groups compared to the control group, there was no statistically significant difference between the increases in P53 mRNA (P = 0.99) and CCND1 mRNA (P = 0.22) index between the groups. The results of this study could be a starting point for a better understanding of the mechanism of genes in PDT of the HNSCC cell line.
{"title":"Effect of Photodynamic Therapy on Cyclin D1 and P53 mRNA Levels in Head and Neck Squamous Cell Carcinoma Cell Line","authors":"M. Koopaie, Mahsan Mosaieby, Zahra Jabbarpour, A. Shamshiri","doi":"10.5812/jamm.107504","DOIUrl":"https://doi.org/10.5812/jamm.107504","url":null,"abstract":"Background: Photodynamic Therapy (PDT) is considered as one of the alternative treatments for Head and Neck Squamous Cell Carcinoma (HNSCC). P53 mRNA is a tumor suppressor gene whose mutation increases the likelihood of uncontrolled cancer-like divisions. The mutation of CCND1 oncogenic increases the production of cyclin D1 as a tumorigenic protein. Objectives: This study aimed to determine the effect of PDT using toluidine blue as a photosensitizer on the CCND1 and P53 mRNA levels in the HNSCC cell line. Methods: A human HNSCC cell line from NCBI.C196 designation HN5 was used. Cells were divided into four groups: Group I (HNSCC cell line under the influence of toluidine blue and laser irradiation), group II (HNSCC cell line under the influence of toluidine blue), group III (HNSCC cell line under laser irradiation), group IV (control group, HNSCC cell line). A 660 nm THOR laser using toluidine blue as a photosensitizer was applied. The RNA extraction was performed in three steps, including cell degradation, purification, and precipitation by alcohol. The cDNA was prepared using Takara Kit. The Amplicon kit and Real-Time PCR analysis were used for the assessment of mRNA relative levels. Results: The P53 mRNA relative levels were 1.50 ± 0.33 in group I (P = 0.65), 1.49 ± 0.23 (P =0.5) in group II, and 1.40 ± 1.05 (P = 0.63) in group III. Compared to the control group, the mean increases in CCND1 mRNA were 18.01 ± 3.37 (p=0.04) in group I, 17.69 ± 3.3 (P = 0.03) in group II, and 9.01 ± 6.17 (P = 0.20) in group III. Conclusions: The comparison of the fold change index for P53 and CCND1 mRNA by the one-way ANOVA test showed that despite the increased expression of P53 and CCND1 mRNA in treatment groups compared to the control group, there was no statistically significant difference between the increases in P53 mRNA (P = 0.99) and CCND1 mRNA (P = 0.22) index between the groups. The results of this study could be a starting point for a better understanding of the mechanism of genes in PDT of the HNSCC cell line.","PeriodicalId":15058,"journal":{"name":"Journal of Archives in Military Medicine","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73872491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Ghadirian, Kobra. Karami, R. Shirzadegan, Zeinab Raiesifar, N. Tahery, M. Almasian
Background: Since surgical interventions often cause damage to tissues, which in turn stimulates the central nervous system, postoperative pain is unavoidable. Objectives: The current study aimed to investigate the effects of French lavender on pain and the amount of medications prescribed to reduce post-appendectomy pain. Methods: In this randomized clinical trial, 120 patients undergoing acute abdominal surgery are recruited. The intervention was defined as inhaling the essential oil of lavender, while those in the placebo group inhaled almond oil. Pain measurement was performed at baseline, half an hour after the first intervention, and after providing the second and third interventions using the Visual Analogue Scale. Results: At all stages of the study, the lavender aroma was associated with a significant reduction in pain (P < 0.0001). Also, the pain intensity was significantly lower in the intervention group than the control (P < 0.0001). Conclusions: The current study demonstrated that aromatherapy is an effective complementary option to reduce postoperative pain and as an analgesic drug.
{"title":"Effects of French Lavender Aromatherapy on the Level of Pain and the Amount of Medications Prescribed to Reduce Post-Appendectomy Pain: A Single-Blind Randomized Clinical Trial","authors":"F. Ghadirian, Kobra. Karami, R. Shirzadegan, Zeinab Raiesifar, N. Tahery, M. Almasian","doi":"10.5812/jamm.109092","DOIUrl":"https://doi.org/10.5812/jamm.109092","url":null,"abstract":"Background: Since surgical interventions often cause damage to tissues, which in turn stimulates the central nervous system, postoperative pain is unavoidable. Objectives: The current study aimed to investigate the effects of French lavender on pain and the amount of medications prescribed to reduce post-appendectomy pain. Methods: In this randomized clinical trial, 120 patients undergoing acute abdominal surgery are recruited. The intervention was defined as inhaling the essential oil of lavender, while those in the placebo group inhaled almond oil. Pain measurement was performed at baseline, half an hour after the first intervention, and after providing the second and third interventions using the Visual Analogue Scale. Results: At all stages of the study, the lavender aroma was associated with a significant reduction in pain (P < 0.0001). Also, the pain intensity was significantly lower in the intervention group than the control (P < 0.0001). Conclusions: The current study demonstrated that aromatherapy is an effective complementary option to reduce postoperative pain and as an analgesic drug.","PeriodicalId":15058,"journal":{"name":"Journal of Archives in Military Medicine","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87586367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Research is limited on the effectiveness of various post-soccer match recovery methods. Objectives: This study aimed to investigate the effects of active recovery methods on performance and muscle damage indices in young male soccer players. Methods: In this study, 21 male subjects (age 16.95 ± 2, height 175.29 ± 4, weight 65.99 ± 5) were selected and divided randomly into three recovery groups after a simulated soccer match. Foam roller recovery included massaging various muscle groups using a foam roller. Recovery by immersion in cold water involved immersing the body up to the neck in cold water at 15 °C. In inactive recovery, the subjects had no activity. The Yo-Yo recovery test, Sargent jump test, 20-m speed test, lactometer, and ELISA tests were used to measure the variables of aerobic power, explosive power, speed, lactate, lactate dehydrogenase, and creatinine kinase, respectively. A two-way ANOVA test with repeated measures was used to determine the differences at a confidence interval of 95%. Results: A significant difference was observed between the foam roller recovery group and the control group 24 hours after the simulated soccer match in muscle damage indices (P value < 0.05). However, in the active recovery group comparison, no significant difference was observed in the performance indices (P value < 0.05). Conclusions: It seems that foam rolling recovery can be used as a useful way to accelerate recovery compared to water immersion recovery through a reduction in inflammatory responses.
{"title":"Effects of Cryotherapy and Foam Rolling Recovery Methods on Performance and Muscle Damage Indices in Young Male Soccer Players After Simulated Soccer Match","authors":"H. Moradi, A. Monazzami","doi":"10.5812/jamm.109361","DOIUrl":"https://doi.org/10.5812/jamm.109361","url":null,"abstract":"Background: Research is limited on the effectiveness of various post-soccer match recovery methods. Objectives: This study aimed to investigate the effects of active recovery methods on performance and muscle damage indices in young male soccer players. Methods: In this study, 21 male subjects (age 16.95 ± 2, height 175.29 ± 4, weight 65.99 ± 5) were selected and divided randomly into three recovery groups after a simulated soccer match. Foam roller recovery included massaging various muscle groups using a foam roller. Recovery by immersion in cold water involved immersing the body up to the neck in cold water at 15 °C. In inactive recovery, the subjects had no activity. The Yo-Yo recovery test, Sargent jump test, 20-m speed test, lactometer, and ELISA tests were used to measure the variables of aerobic power, explosive power, speed, lactate, lactate dehydrogenase, and creatinine kinase, respectively. A two-way ANOVA test with repeated measures was used to determine the differences at a confidence interval of 95%. Results: A significant difference was observed between the foam roller recovery group and the control group 24 hours after the simulated soccer match in muscle damage indices (P value < 0.05). However, in the active recovery group comparison, no significant difference was observed in the performance indices (P value < 0.05). Conclusions: It seems that foam rolling recovery can be used as a useful way to accelerate recovery compared to water immersion recovery through a reduction in inflammatory responses.","PeriodicalId":15058,"journal":{"name":"Journal of Archives in Military Medicine","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82650696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maryam Kaboli, P. Kadivar, M. Abdollahi, M. Arabzadeh
Objectives: The current study aimed to design, develop, and evaluate a germane load-based cognitive rehabilitation program designed for students with special learning disabilities. Methods: The exploratory, descriptive method was used for designing the program. Thematic analysis (Sterling (2001)) was used to estimate the germane load themes. Based on the previous studies, 85 specific germane load codes were identified and evaluated. According to the results, the Multimedia Principle in germane load, Multi-personalization principle, and the Feedback principle consisted of 16, 17, 12 basic themes, respectively. Besides, the Reflection principle, as the most important learning principle in germane load, contained 17 basic themes, and the Guided Activity principle consisted of 8 basic themes. The content validity method was used to validate the program, both quantitatively and qualitatively, with a panel of 10 experts as well as two relative content validity coefficients (CVR) and content validity index (CVI). Results: The minimum and maximum content validity index (CVI) for each article or program component are 0.8 and 1, respectively, and the minimum and maximum content validity index (CVR) for each article or program component are 0.7 and 1, respectively. Conclusions: The results showed that the germane load-based cognitive rehabilitation program for students with special learning disabilities has appropriate content validity as well as the necessary validity for educational, clinical, and research purposes.
{"title":"Designing, Developing, and Evaluation of a Germane Load-Based Cognitive Rehabilitation Program for Students with Specific Learning Disabilities","authors":"Maryam Kaboli, P. Kadivar, M. Abdollahi, M. Arabzadeh","doi":"10.5812/jamm.111339","DOIUrl":"https://doi.org/10.5812/jamm.111339","url":null,"abstract":"Objectives: The current study aimed to design, develop, and evaluate a germane load-based cognitive rehabilitation program designed for students with special learning disabilities. Methods: The exploratory, descriptive method was used for designing the program. Thematic analysis (Sterling (2001)) was used to estimate the germane load themes. Based on the previous studies, 85 specific germane load codes were identified and evaluated. According to the results, the Multimedia Principle in germane load, Multi-personalization principle, and the Feedback principle consisted of 16, 17, 12 basic themes, respectively. Besides, the Reflection principle, as the most important learning principle in germane load, contained 17 basic themes, and the Guided Activity principle consisted of 8 basic themes. The content validity method was used to validate the program, both quantitatively and qualitatively, with a panel of 10 experts as well as two relative content validity coefficients (CVR) and content validity index (CVI). Results: The minimum and maximum content validity index (CVI) for each article or program component are 0.8 and 1, respectively, and the minimum and maximum content validity index (CVR) for each article or program component are 0.7 and 1, respectively. Conclusions: The results showed that the germane load-based cognitive rehabilitation program for students with special learning disabilities has appropriate content validity as well as the necessary validity for educational, clinical, and research purposes.","PeriodicalId":15058,"journal":{"name":"Journal of Archives in Military Medicine","volume":"20 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91482610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Extracorporeal Membrane Oxygenation (ECMO) for COVID-19: Yes or No?","authors":"F. Bahramnezhad, Banafsheh Ghorbani","doi":"10.5812/jamm.108832","DOIUrl":"https://doi.org/10.5812/jamm.108832","url":null,"abstract":"<jats:p />","PeriodicalId":15058,"journal":{"name":"Journal of Archives in Military Medicine","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90349325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Spiritual well-being is the newest dimension of health, which is placed along with the physical, mental, and social aspects of health. Since soldiers in military barracks are exposed to multiple psychological pressures, their psychological well-being can be affected. Objectives: This study aimed to evaluate the spiritual well-being and psychological well-being and the relationship between these two concepts among soldiers in military service. Methods: A descriptive-analytical study was conducted at a military barracks in Iran in 2019. The study population included 301 soldiers selected using a convenience sampling method. Data were collected using three questionnaires for data on sociodemographic, psychological well-being, and spiritual well-being. Results: The results showed that soldiers' spiritual well-being (Mean ± SD: 100.6 ± 12, 30, range: 50 – 120) and Psychological well-being (PWB) (Mean ± SD: 85.85 ± 7.91, range: 48 – 104) were at high levels. Furthermore, a significant correlation was observed between spiritual well-being and psychological well-being (P value< 0.001, r = 0.41). Conclusion: Considering the correlation between spiritual well-being and psychological well-being among soldiers in military service, it is possible to improve their psychological well-being by promoting spiritual well-being. In this regard, more interventional and combination studies are recommended in the field of psychological well-being and spiritual well-being.
{"title":"Spiritual and Psychological Well-Being of Soldiers in Military Barracks: A Case Study in Iran","authors":"M. Fadaei, Mahya Torkaman, Jamileh Farokhzadian","doi":"10.5812/JAMM.108725","DOIUrl":"https://doi.org/10.5812/JAMM.108725","url":null,"abstract":"Background: Spiritual well-being is the newest dimension of health, which is placed along with the physical, mental, and social aspects of health. Since soldiers in military barracks are exposed to multiple psychological pressures, their psychological well-being can be affected. Objectives: This study aimed to evaluate the spiritual well-being and psychological well-being and the relationship between these two concepts among soldiers in military service. Methods: A descriptive-analytical study was conducted at a military barracks in Iran in 2019. The study population included 301 soldiers selected using a convenience sampling method. Data were collected using three questionnaires for data on sociodemographic, psychological well-being, and spiritual well-being. Results: The results showed that soldiers' spiritual well-being (Mean ± SD: 100.6 ± 12, 30, range: 50 – 120) and Psychological well-being (PWB) (Mean ± SD: 85.85 ± 7.91, range: 48 – 104) were at high levels. Furthermore, a significant correlation was observed between spiritual well-being and psychological well-being (P value< 0.001, r = 0.41). Conclusion: Considering the correlation between spiritual well-being and psychological well-being among soldiers in military service, it is possible to improve their psychological well-being by promoting spiritual well-being. In this regard, more interventional and combination studies are recommended in the field of psychological well-being and spiritual well-being.","PeriodicalId":15058,"journal":{"name":"Journal of Archives in Military Medicine","volume":"106 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91521079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Ghasemnian, Mozhgan Usefpour, A. Rahmani, Zeinab Iddehloei
Background: Nowadays, one of the widely used training methods is high-intensity interval training (HIIT). In addition, researchers have stated that long-term, high-intensity training is associated with the production of free radicals in the body. Free radicals also damage liver cells, resulting in increased liver enzymes. Objectives: The objective of this study was to investigate the effect of HIIT, compared to high-intensity continuous training (HICT), on damage and antioxidant indices of the liver in male Wistar rats. Methods: Twenty-two adult male rats were randomly divided into three groups of control (n = 6), HIIT (n = 8), and HICT (n = 8). Training protocols included HIIT and HICT on a treadmill for eight weeks (five days in a week). Standard water and food were provided for rats ad libitum. Forty-eight hours after the last training session, blood and tissue samples were collected, and serum enzymes were measured by the methods recommended by the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) method. The level of enzyme activity of superoxide dismutase in the liver tissue was measured by Randox Commercial Kit (Cat. No. SD 126). One-way analysis of variance (ANOVA) and Tukey’s post hoc tests were used to analyze the data. Results: The results showed that eight weeks of HIIT and HICT had no effect on the alanine aminotransferase (ALT) level (P = 0.14), but eight weeks of HIIT significantly decreased the serum aspartate aminotransferase (AST) level compared to the control group (P = 0.04). The level of liver superoxide dismutase (SOD) enzyme activity significantly increased in the HIIT and HICT groups compared to the control group (P = 0.001). HICT also led to a significant increase in the SOD level compared to HIIT (P = 0.03). Conclusions: The research results suggested that eight weeks of HIIT led to a significant reduction in serum AST levels, and HIIT had a lower effect on the increased SOD activity in liver tissue compared to HICT. It might be stated that HIIT is safer than HICT, and it has fewer destructive effects on liver tissue.
{"title":"Comparing the Effect of Two Methods of High-Intensity Interval Training (HIIT) and High-Intensity Continuous Training (HICT) on Damage and Antioxidant Indices of Liver in Male Wistar Rats","authors":"A. Ghasemnian, Mozhgan Usefpour, A. Rahmani, Zeinab Iddehloei","doi":"10.5812/JAMM.100409","DOIUrl":"https://doi.org/10.5812/JAMM.100409","url":null,"abstract":"Background: Nowadays, one of the widely used training methods is high-intensity interval training (HIIT). In addition, researchers have stated that long-term, high-intensity training is associated with the production of free radicals in the body. Free radicals also damage liver cells, resulting in increased liver enzymes. Objectives: The objective of this study was to investigate the effect of HIIT, compared to high-intensity continuous training (HICT), on damage and antioxidant indices of the liver in male Wistar rats. Methods: Twenty-two adult male rats were randomly divided into three groups of control (n = 6), HIIT (n = 8), and HICT (n = 8). Training protocols included HIIT and HICT on a treadmill for eight weeks (five days in a week). Standard water and food were provided for rats ad libitum. Forty-eight hours after the last training session, blood and tissue samples were collected, and serum enzymes were measured by the methods recommended by the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) method. The level of enzyme activity of superoxide dismutase in the liver tissue was measured by Randox Commercial Kit (Cat. No. SD 126). One-way analysis of variance (ANOVA) and Tukey’s post hoc tests were used to analyze the data. Results: The results showed that eight weeks of HIIT and HICT had no effect on the alanine aminotransferase (ALT) level (P = 0.14), but eight weeks of HIIT significantly decreased the serum aspartate aminotransferase (AST) level compared to the control group (P = 0.04). The level of liver superoxide dismutase (SOD) enzyme activity significantly increased in the HIIT and HICT groups compared to the control group (P = 0.001). HICT also led to a significant increase in the SOD level compared to HIIT (P = 0.03). Conclusions: The research results suggested that eight weeks of HIIT led to a significant reduction in serum AST levels, and HIIT had a lower effect on the increased SOD activity in liver tissue compared to HICT. It might be stated that HIIT is safer than HICT, and it has fewer destructive effects on liver tissue.","PeriodicalId":15058,"journal":{"name":"Journal of Archives in Military Medicine","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87850485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reyhaneh Yaghobzadeh, Seyyed Reza Kamel, K. Shirazi
: The new coronavirus disease 2019 (COVID-19) has recently emerged as an acute respiratory syndrome. The virus has spread throughout the world since the primary outbreak of the disease reported in Wuhan, China. The pandemic has led to increased mortality as the most important threat of the disease in specific populations across the world. Furthermore, COVID-19 has caused significant economic problems in several countries. The early diagnosis of COVID-19 is currently an important concern for physicians and communities. The present study aimed to review the published articles regarding the diagnosis of COVID-19 until the end of February 2020. According to the results we show that deep learning and machine learning algorithms can be effectively used to the scope of the disease.
{"title":"A Review of COVID-19 Diagnostic Methods","authors":"Reyhaneh Yaghobzadeh, Seyyed Reza Kamel, K. Shirazi","doi":"10.5812/JAMM.106802","DOIUrl":"https://doi.org/10.5812/JAMM.106802","url":null,"abstract":": The new coronavirus disease 2019 (COVID-19) has recently emerged as an acute respiratory syndrome. The virus has spread throughout the world since the primary outbreak of the disease reported in Wuhan, China. The pandemic has led to increased mortality as the most important threat of the disease in specific populations across the world. Furthermore, COVID-19 has caused significant economic problems in several countries. The early diagnosis of COVID-19 is currently an important concern for physicians and communities. The present study aimed to review the published articles regarding the diagnosis of COVID-19 until the end of February 2020. According to the results we show that deep learning and machine learning algorithms can be effectively used to the scope of the disease.","PeriodicalId":15058,"journal":{"name":"Journal of Archives in Military Medicine","volume":"3 6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78504322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Moeen Ranjbar, S. Z. Hejripour, M. Darvishi, E. Karimi
Background: The mortality rate of out-of-hospital cardiac arrest (OHCA) is high and it's shown that bystander CPR increases the survival rate of these patients by two to three-folds. Several methods are introduced to improve the acquisition and retention of CPR-related knowledge learned in courses. Objectives: The current study aimed to compare three different methods of teaching CPR in terms of primary acquisition and retention of such skills in soldiers. Methods: This study was performed from November 2019 to February 2020 on selected duty male soldiers doing their military service. Participants were randomized into 1 of the following 4 groups: (1) A lecture-based, 30-minute class session followed by a one-hour practice on a manikin; (2) a 20-minute instructional video followed by a one-hour practice on a manikin; (3) a 20-minute instructional video without practice on a manikin (video only); and (4) no intervention. The performance and retention of CPR skills were assessed using a checklist by two referees. The preparation score, ABC score, and total score were assessed using this checklist. Results: Fifty male participants with a mean age of 22.44 ± 2.08 years were included. The median score of groups 1 - 3 increased significantly after the intervention compared to the pre-test results. Group 3 (video only) experienced the highest increment in the preparation score (2.30). Concerning the ABC and total scores, group 1 (class session) showed the highest increment of scores (22.70 and 24.82, respectively). Group 3 (video only) showed the most sustained results compared to groups 1 and 2 one month after the intervention. Conclusions: According to the results, the classroom session teaching with a manikin practice accompanied better acquisition of CPR skills. However, the retention of CPR skills is better maintained with a simple video-only method.
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