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Dynamical systems theory applied to short walking trials 应用于短距离行走试验的动力系统理论
IF 2.4 3区 医学 Q3 BIOPHYSICS Pub Date : 2024-09-21 DOI: 10.1016/j.jbiomech.2024.112331
Human walking is an extremely complex neuromuscular activity whose simplicity disappears when an attempt is made to provide a quantitative description of the process. The dynamical systems theory provides a framework for analyzing the stability and chaotic nature of dynamical systems, employing Floquet multipliers (FM) and long and short-term Lyapunov exponents (LE), respectively. This report compares FM and LE from three methods: method A (false nearest neighbors and numerical approximation), method B (false nearest neighbors and semi-analytical technique) and method C (singular value decomposition and semi-analytical technique). Data from 33 healthy older adults with no history of falls were used to explain the dynamic system. A surrogate center of mass trajectory was calculated for the analysis of sway in the transverse plane. Results revealed methodological differences in LE and FM calculations with semi-analytical solutions providing closer approximations to observed gait behavior. The long-term LE from Methods A and B were similar, but other LE pairings differed. Method A’s short-term LE indicated chaotic gaits for all subjects, while long-term LE from Methods A and B indicated chaos for half the subjects. Method C showed non-chaotic gait for most subjects. Method B’s FM indicated over 30% of subjects had unstable gait. Method C yielded values of LE and FM that most closely matched the subjects’ gait patterns. This study offers a methodological foundation for gait analysis using short time-series data, facilitating deeper insights into both stability and chaos within gait dynamics.
人类行走是一项极其复杂的神经肌肉活动,如果试图对这一过程进行定量描述,其简单性将不复存在。动力系统理论为分析动力系统的稳定性和混沌性提供了一个框架,分别采用了 Floquet 乘数(FM)和长期及短期 Lyapunov 指数(LE)。本报告比较了三种方法的 FM 和 LE:方法 A(假近邻和数值近似)、方法 B(假近邻和半分析技术)和方法 C(奇异值分解和半分析技术)。33 名无跌倒史的健康老年人的数据被用来解释动态系统。为分析横向平面的摇摆,计算了代理质心轨迹。结果显示,LE 和 FM 的计算方法存在差异,半分析法更接近观察到的步态行为。方法 A 和 B 的长期 LE 相似,但其他 LE 配对不同。方法 A 的短期 LE 显示所有受试者的步态都是混乱的,而方法 A 和 B 的长期 LE 则显示半数受试者的步态是混乱的。方法 C 显示大多数受试者的步态不混乱。方法 B 的 FM 显示超过 30% 的受试者步态不稳定。方法 C 得出的 LE 值和 FM 值最接近受试者的步态模式。这项研究为使用短时间序列数据进行步态分析提供了方法论基础,有助于深入了解步态动态中的稳定性和混乱性。
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引用次数: 0
Relationship of shoulder internal and external rotation peak force and rate of force development to throwing velocity in high school and collegiate pitchers 高中生和大学生投手的肩关节内旋和外旋峰值力量以及力量发展速度与投掷速度的关系
IF 2.4 3区 医学 Q3 BIOPHYSICS Pub Date : 2024-09-21 DOI: 10.1016/j.jbiomech.2024.112339
The purpose of this research was to characterize the difference between high school (HS) and collegiate pitcher’s throwing velocity, shoulder internal (IR) and external rotator (ER) maximum strength (Fmax) and rate of force development (RFD) and explore relationships between these measures. Competitive HS and collegiate pitchers (n = 26) participated in a single session assessment in which shoulder rotator isometric Fmax and RFD were quantified via a portable strain gauge device and throwing velocity via radar. Paired t-tests, stepwise linear regression models and correlational analyses were used to answer the questions of interest. No significant differences (p > 0.05) in pitching velocity were observed between HS and collegiate pitchers, and all pitchers were pooled into one sample for subsequent analyses. For both IR and ER models, the explained variance of Fmax with throwing velocity was small (R2 = 0.12–0.13). RFD and arm length did not contribute to the models. Large correlations (r ≥ 0.50; p < 0.001) were observed between IR and ER for Fmax and RFD measures, as well as between Fmax and RFD for IR and ER. In terms of throwing velocity, having strong IR and ER Fmax capabilities would seem more important than the ability to express force quickly in this cohort.
本研究的目的是描述高中(HS)和大学投手的投掷速度、肩部内旋(IR)和外旋(ER)最大力量(Fmax)和力量发展速度(RFD)之间的差异,并探索这些指标之间的关系。具有竞争力的高中和大学投手(n = 26)参加了单次评估,通过便携式应变仪设备对肩部旋转肌等长最大力量和RFD进行量化,并通过雷达对投掷速度进行量化。采用配对 t 检验、逐步线性回归模型和相关分析来回答相关问题。在投球速度方面,高中生和大学生投手之间没有发现明显差异(p > 0.05),所有投手都被集中到一个样本中进行后续分析。在 IR 和 ER 模型中,Fmax 与投掷速度的解释方差都很小(R2 = 0.12-0.13)。RFD和臂长对模型没有贡献。IR和ER的Fmax和RFD测量值之间以及IR和ER的Fmax和RFD测量值之间存在较大的相关性(r≥0.50;p < 0.001)。就投掷速度而言,在该组人群中,拥有强大的IR和ER最大投掷能力似乎比快速发力能力更为重要。
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引用次数: 0
Prediction of sperm motion behavior in microfluidic channel using sperm swimming model 利用精子游动模型预测微流体通道中的精子运动行为
IF 2.4 3区 医学 Q3 BIOPHYSICS Pub Date : 2024-09-20 DOI: 10.1016/j.jbiomech.2024.112336
Several investigations have recently been conducted using microfluidic channels to sort highly motile sperm and thereby increase the probability of fertilization. To further enhance the efficiency of sperm sorting, predicting sperm movement in microfluidic channels through simulation techniques could be beneficial. In this study, we constructed a sperm swimming model based on the concept of an agent-based model. This model allows analysis at the same spatio–temporal scale similar to microfluidic channels. Sperm movement was simplistically modeled as a random walk, utilizing the distribution of sperm velocity and deflection angle obtained from experimental data. We have developed a thigmotaxis model to describe the phenomenon where sperm near the wall exhibit a reduced tendency to move away from it. Additionally, we created a rheotaxis model, in which sperm reorient in the direction opposite to the flow depending on the shear rate. Using these models, we investigated sperm behaviors within a microchannel featuring a tapered area. The results reveal that sperm accumulate within the tapered area, leading to a significant increase in sperm concentration for specific flow velocity ranges in the microchannel. This model provides valuable information for predicting the effects of sperm sorting in various microfluidic channels.
最近有几项研究利用微流体通道对高运动性精子进行分拣,从而提高受精几率。为了进一步提高精子分拣的效率,通过模拟技术预测精子在微流控通道中的运动可能是有益的。在这项研究中,我们根据基于代理的模型概念构建了一个精子游动模型。该模型可在与微流控通道类似的时空尺度上进行分析。利用从实验数据中获得的精子速度和偏转角度分布,精子运动被简化为随机行走。我们建立了一个thigmotaxis模型来描述精子在靠近壁面时表现出远离壁面的趋势减弱的现象。此外,我们还建立了一个流变模型,在该模型中,精子会根据剪切率向与水流相反的方向重新定向。利用这些模型,我们研究了精子在具有锥形区域的微通道内的行为。结果显示,精子在锥形区域内聚集,导致微通道中特定流速范围内的精子浓度显著增加。该模型为预测精子在各种微流控通道中的分拣效果提供了有价值的信息。
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引用次数: 0
Kinematic–kinetic compliant acetabular cup positioning based on preoperative motion tracking and musculoskeletal modeling for total hip arthroplasty 基于全髋关节置换术术前运动跟踪和肌肉骨骼建模的运动学-动力学顺应性髋臼杯定位
IF 2.4 3区 医学 Q3 BIOPHYSICS Pub Date : 2024-09-19 DOI: 10.1016/j.jbiomech.2024.112332
The invention of the surgical robot enabled accurate component implantation during total hip arthroplasty (THA). However, a preoperative surgical planning methodology is still lacking to determine the acetabular cup alignment considering the patient-specific hip functions during daily activities such as walking. To simultaneously avoid implant edgeloading and impingement, this study established a kinematic–kinetic compliant (KKC) acetabular cup positioning method based on preoperative gait kinematics measurement and musculoskeletal modeling. Computed tomography images around the hip joint and their biomechanical data during gait, including motion tracking and foot–ground reaction forces, were collected. Using the reconstructed pelvic and femur geometries, the patient-specific hip muscle insertions were located in the lower limb musculoskeletal model via point cloud registration. The designed cup orientation has to be within the patient-specific safe zone to prevent implant impingement, and the optimized value selected based on the time-dependent hip joint reaction force to minimize the risk of edgeloading. As a validation of the proposed musculoskeletal model, the predicted lower limb muscle activations for seven patients were correlated with their surface electromyographic measurements, and the computed hip contact force was also in quantitative agreement with data from the literature. However, the designed cup orientations were not always within the well-known Lewinnek safe zone, highlighting the importance of KKC surgical planning based on patient-specific biomechanical evaluations.
手术机器人的发明实现了全髋关节置换术(THA)中部件的精确植入。然而,考虑到患者在行走等日常活动中的特定髋关节功能,目前仍缺乏一种术前手术规划方法来确定髋臼杯的对位。为了同时避免假体边缘堆积和撞击,本研究基于术前步态运动学测量和肌肉骨骼建模,建立了一种运动学-动力学顺应性(KKC)髋臼杯定位方法。该方法收集了髋关节周围的计算机断层扫描图像及其步态过程中的生物力学数据,包括运动跟踪和足底反作用力。利用重建的骨盆和股骨几何图形,通过点云注册在下肢肌肉骨骼模型中定位患者特定的髋部肌肉插入点。设计的髋臼杯方向必须在患者特定的安全区域内,以防止植入物撞击,并根据随时间变化的髋关节反作用力选择优化值,以最大限度地降低边缘塌陷的风险。作为对提出的肌肉骨骼模型的验证,七名患者的预测下肢肌肉激活与他们的表面肌电图测量结果相关,计算出的髋关节接触力也与文献数据在数量上一致。然而,设计的髋臼杯方向并不总是在众所周知的卢因内克安全区范围内,这就凸显了根据患者的具体生物力学评估进行 KKC 手术规划的重要性。
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引用次数: 0
Do osteophytes alter thumb carpometacarpal Biomechanics? a preliminary in vitro study 骨质增生会改变拇指腕掌骨生物力学吗?
IF 2.4 3区 医学 Q3 BIOPHYSICS Pub Date : 2024-09-19 DOI: 10.1016/j.jbiomech.2024.112333
Osteoarthritis (OA) of the thumb carpometacarpal (CMC) joint is prevalent and debilitating, marked by substantial loss of range of motion (ROM) and overall function. CMC OA is associated with osteophyte growth, but the impact of this growth on CMC ROM has not been systematically characterized. Our goal was to determine whether osteophytes decrease CMC ROM and, if so, whether these decreases are direction-dependent. A robotic musculoskeletal simulation system was used to manipulate 18 CMC specimens with a range of joint health following three test protocols: (1) Rotational ROM in flexion, extension, abduction, adduction, and 20 combined directions, (2) Internal/External Rotation (IR/ER), and (3) Translational ROM in volar, dorsal, radial, ulnar, and 4 combined directions. Osteophyte volume (OV) was computed in total and by volar, dorsal, radial, and ulnar quadrants, and correlations with ROM were computed by direction and in total. We found that an increase in overall trapezial OV was associated with a reduction in overall rotational ROM and IR/ER, but not with translational ROM. We found decreased extension was associated with increased ulnar, volar, and radial OV, and decreased abduction was associated with increased volar OV. Decreased internal rotation was associated with increased ulnar, volar, and radial OV. The proposed method and findings of this pilot study will lay the groundwork for a larger investigation into the relationship between pathological structure and function in the CMC joint.
拇指腕掌骨(CMC)关节骨关节炎(OA)是一种常见的衰弱性疾病,主要表现为活动范围(ROM)和整体功能的严重丧失。CMC OA 与骨质增生有关,但骨质增生对 CMC ROM 的影响尚未得到系统研究。我们的目标是确定骨质增生是否会减小 CMC ROM,如果是,这种减小是否与方向有关。我们使用机器人肌肉骨骼模拟系统对 18 个 CMC 标本进行了操作,并按照三个测试方案进行了关节健康范围的测试:(1)屈、伸、外展、内收和 20 个组合方向的旋转 ROM;(2)内/外旋(IR/ER);(3)外侧、背侧、桡侧、尺侧和 4 个组合方向的平移 ROM。我们计算了骨质增生体积(OV)的总和,并按外侧、背侧、桡侧和尺侧象限进行了计算,还按方向和总和计算了骨质增生体积与 ROM 的相关性。我们发现,整个斜方肌OV的增加与整体旋转ROM和IR/ER的减少有关,但与平移ROM无关。我们发现,伸展减少与尺侧、伏侧和桡侧OV增加有关,外展减少与伏侧OV增加有关。内旋减少与尺侧、足侧和桡侧OV增加有关。这项试验性研究提出的方法和结果将为进一步研究 CMC 关节病理结构与功能之间的关系奠定基础。
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引用次数: 0
Repeatability of two methods for estimating scapular kinematics during dynamic functional tasks 估算动态功能任务中肩胛骨运动学的两种方法的重复性
IF 2.4 3区 医学 Q3 BIOPHYSICS Pub Date : 2024-09-18 DOI: 10.1016/j.jbiomech.2024.112334

Best practices for scapular motion tracking are still being determined. The repeatability of different scapular kinematic procedures needs to be evaluated. The purpose of this study was to assess the test-retest reliability of two scapular kinematic procedures: double calibration with AMC (D-AMC) and individualized linear modelling (LM). Ten healthy participants had their upper body movement tracked with optical motion capture in two identical sessions. Five scapular calibration poses were performed, and seven dynamic functional tasks were tested. Scapular angles were calculated from both procedures (D-AMC vs LM). The D-AMC approach uses two poses (neutral and maximum elevation) and tracks the scapula with a rigid cluster, while the LM approach predicts scapular positioning from humeral angles based on equations built from the calibration pose data. Angle waveforms and repeatability outcomes were compared. Internal and upward rotation angle waveforms were significantly different (p < 0.05) between kinematic procedures for some tasks, with maximum mean differences up to 17.3° and 23.2°, respectively. Overall, repeatability outcomes were similar between procedures, but the LM approach was slightly better for tilt and the D-AMC approach was notably improved for upward rotation in certain tasks. For example, minimal detectable changes during the Forward Transfer ranged from 6.9° to 11.9° for the D-AMC and 8.9° to 25.3° for the LM. Discrepancies between procedures may be a function of the calibration poses chosen. Additional calibration poses may improve the comparisons between procedures.

肩胛运动跟踪的最佳实践仍在确定之中。需要对不同肩胛运动学程序的重复性进行评估。本研究旨在评估两种肩胛骨运动学程序的重复测试可靠性:AMC 双校准(D-AMC)和个性化线性建模(LM)。十名健康参与者在两次相同的训练中使用光学运动捕捉对他们的上半身运动进行了跟踪。进行了五次肩胛骨校准姿势,并测试了七项动态功能任务。两种方法(D-AMC 与 LM)都计算出了肩胛角。D-AMC 方法使用两个姿势(中立和最大仰角),并用刚性集群跟踪肩胛骨,而 LM 方法则根据校准姿势数据建立的方程,从肱骨角度预测肩胛骨定位。对角度波形和重复性结果进行了比较。在某些任务中,不同运动学程序的内旋和上旋角度波形有显著差异(p < 0.05),最大平均差异分别高达 17.3° 和 23.2°。总体而言,不同程序之间的重复性结果相似,但在某些任务中,LM 方法在倾斜方面略胜一筹,D-AMC 方法在向上旋转方面有明显改善。例如,在 "前向转移 "过程中,D-AMC方法可检测到的最小变化范围为6.9°至11.9°,LM方法为8.9°至25.3°。程序之间的差异可能与所选的校准姿势有关。额外的校准姿势可能会改善程序之间的比较。
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引用次数: 0
In Silico clinical trial to predict the efficacy of hip protectors for preventing hip fractures 预测髋部保护器预防髋部骨折疗效的硅学临床试验
IF 2.4 3区 医学 Q3 BIOPHYSICS Pub Date : 2024-09-18 DOI: 10.1016/j.jbiomech.2024.112335

Osteoporosis is characterized by loss of bone mineral density and increased fracture risk. Reduction of hip fracture incidence is of major clinical importance. Hip protectors aim to attenuate the impact force transmitted to the femur upon falling, however different conclusions on their efficacy have been reported; some authors suggest this may be due to differences in compliance. The aim of this study was to apply an In Silico trial methodology to predict the effectiveness of hip protectors and its dependence on compliance.

A cohort of 1044 virtual patients (Finite Element models of proximal femur) were generated. A Markov chain process was implemented to predict fracture incidence with and without hip protectors, by simulating different levels of compliance. At each simulated follow-up year, a Poisson distribution was randomly sampled to determine the number of falls sustained by each patient. Impact direction and force were stochastically sampled from a range of possible scenarios. The effect of wearing a hip protector was simulated by applying attenuation coefficients to the impact force (12.9 %, 19 % and 33.8 %, as reported for available devices). A patient was considered fractured when impact force exceeded the femur strength.

Without hip protector, virtual patients experienced 66 ± 5 fractures in 10 years. Wearing the three devices, fracture incidence was reduced to 43 ± 4, 35 ± 4 and 17 ± 2 respectively, at full compliance. As expected, effectiveness was dependent on compliance.

This In Silico trial technology can be applied in the future to test multiple interventions, optimise intervention strategies, improve clinical trial design and drug development.

骨质疏松症的特点是骨矿物质密度下降和骨折风险增加。降低髋部骨折的发生率具有重要的临床意义。髋部保护器旨在减弱跌倒时传递到股骨的冲击力,但有关其功效的结论却不尽相同;一些作者认为这可能是由于顺应性的差异造成的。本研究的目的是应用 In Silico 试验方法来预测护髋的有效性及其对顺应性的依赖性。通过模拟不同程度的依从性,实施马尔可夫链过程来预测使用和不使用髋部保护器的骨折发生率。在每个模拟随访年,随机抽取泊松分布,以确定每位患者的跌倒次数。撞击方向和撞击力从一系列可能的情况中随机取样。通过对撞击力应用衰减系数(12.9%、19% 和 33.8%,根据现有设备的报告)来模拟佩戴髋部保护器的效果。当冲击力超过股骨强度时,患者即被视为骨折。如果不佩戴髋关节保护器,虚拟患者在 10 年内会发生 66 ± 5 次骨折。佩戴这三种装置后,骨折发生率在完全达标的情况下分别降至 43 ± 4、35 ± 4 和 17 ± 2。正如预期的那样,有效性取决于依从性。这种 In Silico 试验技术今后可用于测试多种干预措施、优化干预策略、改进临床试验设计和药物开发。
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引用次数: 0
Simulating vortex generation to investigate the propulsive and braking mechanisms of breaststroke kick using computational fluid dynamics on a breaststroke swimmer 利用蛙泳运动员的计算流体动力学模拟涡流产生,研究蛙泳踢腿的推进和制动机制
IF 2.4 3区 医学 Q3 BIOPHYSICS Pub Date : 2024-09-17 DOI: 10.1016/j.jbiomech.2024.112329

Swimmers primarily increase their forward velocity through lower limb motion in breaststroke, making the breaststroke kick crucial for optimizing race times. Recent studies have highlighted the generation of vortices around the swimmer’s entire body to propel forward during swimming. However, the investigation of vortex generation during breaststroke kicks remains unexplored. This study aimed to reveal the propulsive and braking mechanisms of breaststroke kicks by simulating vortex generation using computational fluid dynamics (CFD). Kinematic data during the breaststroke kick and a three-dimensional digital model were collected to conduct CFD for a male breaststroke swimmer. Vortex generation was determined during one breaststroke kick from the CFD results. Vortices, which potentially induce a decrease in forward velocity, were generated by the swimmer’s lower legs and feet during the recovery phase. The swimmer generated vortices on the dorsal side of the feet and the posterior and lateral sides of the lower legs to increase the forward velocity during the out-sweep phase. The swimmer generated vortices on the lateral sides of the thighs and lower legs and the dorsal and lateral sides of the feet during the in-sweep phase to maintain forward velocity. Moreover, vortices generated from the out-sweep to the in-sweep merged and were shed backward relative to the swimming direction after the in-sweep phase. This study is the first to reveal the propulsive and braking mechanisms of breaststroke kicks by analyzing the vortex generation.

游泳运动员在蛙泳中主要通过下肢运动提高前进速度,因此蛙泳踢腿对于优化比赛时间至关重要。最近的研究强调了游泳时游泳者整个身体周围产生的涡流推动前进。然而,对蛙泳踢腿时涡流产生的研究仍未展开。本研究旨在通过使用计算流体动力学(CFD)模拟涡流的产生,揭示蛙泳踢腿时的推进和制动机制。研究收集了一名男子蛙泳运动员在蛙泳踢腿过程中的运动学数据和三维数字模型,以进行 CFD 模拟。根据 CFD 结果确定了一次蛙泳踢腿过程中产生的涡流。在恢复阶段,有可能导致前进速度降低的涡流是由游泳者的小腿和脚产生的。在外侧扫水阶段,游泳者在脚背、小腿后侧和外侧产生涡流,以提高前进速度。在内侧扫水阶段,游泳者在大腿和小腿外侧以及脚背和外侧产生涡流,以保持前进速度。此外,从出泳到进泳产生的涡流在进泳阶段后合并并相对于游泳方向向后脱落。这项研究首次通过分析涡流的产生揭示了蛙泳踢腿的推进和制动机制。
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引用次数: 0
Walking in a controlled ankle motion (CAM) boot: In-boot measurement of joint kinematics and kinetics 穿着受控踝关节运动(CAM)靴行走:靴内关节运动学和动力学测量
IF 2.4 3区 医学 Q3 BIOPHYSICS Pub Date : 2024-09-16 DOI: 10.1016/j.jbiomech.2024.112327

Research investigating ankle function during walking in a controlled ankle motion (CAM) boot has either placed markers on the outside of the boot or made major alterations to the structure of the CAM boot to uncover key landmarks. The aim of this study was to quantify joint kinematics and kinetics using “in-boot” skin markers whilst making only minimal structural alterations. Seventeen healthy participants walked at their preferred walking speed in two conditions: (1) in standard athletic trainers (ASICS patriot 8, ASICS Oceania Pty Ltd, USA), and (2) using a hard-cased CAM boot (Rebound® Air Walker, Össur, Iceland) fitted on the right foot. Kinematic measurements revealed that CAM boots restrict sagittal plane ankle range of motion to less than 5°, and to ∼3° in the frontal plane, which is a reduction of 85% and 73% compared to standard footwear, respectively (p < 0.001). This ankle restriction resulted in a reduction of ankle joint total limb work contribution from 38 ± 5% in normal footwear to 13 ± 4% in the CAM boot (p < 0.001). This study suggests that CAM boots do restrict the ankle joint’s ability to effectively perform work during walking, which leads to compensatory mechanisms at the ipsilateral and contralateral hip and knee joints. Our findings align with previous research that employed “on-boot” kinematic measurements, so we conclude that in-boot approaches do not offer any benefit to the researcher and instead, on-boot measurements are suitable.

对穿着受控踝关节运动(CAM)靴行走时踝关节功能的研究,要么是在靴子外部放置标记,要么是对 CAM 靴子的结构进行重大改动以发现关键地标。本研究旨在使用 "靴内 "皮肤标记对关节运动学和动力学进行量化,同时只对结构进行最小程度的改动。17 名健康参与者在两种条件下以自己喜欢的步行速度行走:(1) 穿着标准运动训练鞋(ASICS patriot 8,ASICS Oceania Pty Ltd,美国);(2) 右脚穿着硬壳 CAM 靴(Rebound® Air Walker,Össur,冰岛)。运动学测量显示,CAM 靴将矢状面的踝关节活动范围限制在 5° 以下,在正面的活动范围限制在 3° 以下,与标准鞋相比分别减少了 85% 和 73%(p < 0.001)。这种踝关节限制导致踝关节的肢体总工作贡献从穿普通鞋时的 38±5% 减少到穿 CAM 靴时的 13±4% (p < 0.001)。这项研究表明,CAM 靴确实限制了踝关节在行走过程中有效做功的能力,从而导致同侧和对侧髋关节和膝关节的代偿机制。我们的研究结果与之前采用 "靴上 "运动学测量方法的研究结果一致,因此我们得出结论,靴上测量方法不会给研究人员带来任何益处,相反,靴上测量方法是合适的。
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引用次数: 0
Quantitative measurement of the flow depending nasal valve function by elastography with electro-optical distance sensors. A pilot study 利用电子光学距离传感器进行弹性成像,定量测量流量对鼻瓣膜功能的影响。试点研究
IF 2.4 3区 医学 Q3 BIOPHYSICS Pub Date : 2024-09-14 DOI: 10.1016/j.jbiomech.2024.112326

Nasal valve function depends on the intensity of the inspiratory nasal airflow, the geometry of the nasal entrance and the mechanical properties of the lateral nasal wall. It is desirable to obtain objective information on the relation between flow and valve movement. In this study, the deflection of the lateral nasal wall and the inspiratory flow were measured on 30 healthy volunteers, aged 18 to 82 without a history of severe trauma or nasal surgery. Electro-optical distance sensors were housed under a full-face protective mask attached to an analogue inspiratory flowmeter. The mean values for normal breathing were assessed at 675 [cm3/s] for the bilateral flow and −0.57 mm for the total movement. With forced breathing, the mean values for the flow of both nostrils were found to be 1434 cm3/s and for the total movement −1.21 mm. Statistically significant differences between normal and forced breathing were found in all participants and in both sexes, but no significant correlation by age. Electro-optical distance measurement, representing a novel technical way for the ‘elastography’ of the nasal valve should be added to advanced 4-phase-rhinomanometers.

鼻瓣膜的功能取决于吸气时鼻腔气流的强度、鼻腔入口的几何形状和鼻侧壁的机械特性。最好能获得有关气流和瓣膜运动之间关系的客观信息。在这项研究中,对 30 名年龄在 18 至 82 岁之间、无严重外伤或鼻部手术史的健康志愿者进行了鼻侧壁偏转和吸气流量的测量。电子光学距离传感器安装在全脸防护面罩下,与模拟吸气流量计相连。据评估,正常呼吸时,双侧流量的平均值为 675 [cm3/s],总移动量为-0.57 mm。强制呼吸时,双侧鼻孔流量的平均值为 1434 立方厘米/秒,总移动量为-1.21 毫米。所有参与者和男女在正常呼吸和强制呼吸之间都发现了明显的统计学差异,但与年龄没有明显的相关性。电子光学距离测量是鼻腔瓣膜 "弹性成像 "的一种新技术方法,应添加到先进的四相血压计中。
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引用次数: 0
期刊
Journal of biomechanics
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