Journal of biomechanics最新文献_第7页

Effect of neural mode on model estimates of muscle contributions to knee loading in individuals with anterior cruciate ligament reconstruction 神经模式对前交叉韧带重建个体肌肉对膝关节负荷的模型估计的影响

IF 2.4 3区医学 Q3 BIOPHYSICS

Journal of biomechanics

Pub Date : 2025-12-10 DOI: 10.1016/j.jbiomech.2025.113120

Fatemeh Bahramian , Azadeh Nasseri , William du Moulin , Jason Konrath , Riad Akhundov , Claire Crossley , David Graham , David John Saxby

This study examined the effect of neural mode (i.e., static optimisation (SO) or Calibrated Electromyography-Informed Neuromusculoskeletal Modelling (CEINMS)) on model estimated muscle contributions to knee loading in individuals with anterior cruciate ligament reconstruction (ACLR) during side-step cutting. Eleven individuals with ACLR completed pre-planned sidestep cutting in a gait laboratory while their whole-body motions, body-ground reaction forces, and electromyography (EMG) from major knee-spanning muscles were acquired. Neuromusculoskeletal modelling simulations were performed using both SO and CEINMS methods to estimate muscle contributions to anteroposterior force, varus/valgus moments, and internal/external rotation moments at the knee. Both SO and CEINMS neural modes accurately predicted body-ground reaction forces. Moderate-to-strong coefficients of determination were found between CEINMS and SO estimates of muscle contributions to knee loads. Irrespective of neural mode, quadriceps were the dominant cause of anterior force, valgus moment, and external rotation moment at the knee, while hamstrings contributed most to the knee’s posterior force and internal rotation moment. Non-knee-spanning muscles also contributed to knee loads, with small between-mode differences in these contributions. In conclusion, both neural modes well predicted whole-body mechanics (i.e., body-ground reaction forces) and differences between neural modes became more pronounced as the focus of analysis moved from general (e.g., net body-ground loads) to knee-specific mechanics.

本研究考察了神经模式（即静态优化（SO）或校准肌电图信息神经肌肉骨骼模型（CEINMS））对前交叉韧带重建（ACLR）患者侧步切割过程中肌肉对膝关节负荷的模型估计的影响。11名ACLR患者在步态实验室中完成了预先计划的侧身切割，同时获得了他们的全身运动、身体-地面反作用力和膝关节主要跨肌的肌电图（EMG）。使用SO和CEINMS方法进行神经肌肉骨骼建模模拟，以估计肌肉对膝关节前后力、内翻/外翻力矩和内/外旋转力矩的贡献。SO和CEINMS神经模式均能准确预测体-地反作用力。在CEINMS和SO估计肌肉对膝关节负荷的贡献之间发现了中等到强的决定系数。无论神经模式如何，股四头肌是膝关节前向力、外翻力矩和外旋力矩的主要原因，而腘绳肌是膝关节后向力和内旋力矩的主要原因。非跨膝肌肉也对膝关节负荷有贡献，在这些贡献上有很小的模式差异。总之，两种神经模式都能很好地预测全身力学（即身体-地面反作用力），随着分析的重点从一般力学（如净身体-地面载荷）转移到膝盖特定力学，神经模式之间的差异变得更加明显。

{"title":"Effect of neural mode on model estimates of muscle contributions to knee loading in individuals with anterior cruciate ligament reconstruction","authors":"Fatemeh Bahramian , Azadeh Nasseri , William du Moulin , Jason Konrath , Riad Akhundov , Claire Crossley , David Graham , David John Saxby","doi":"10.1016/j.jbiomech.2025.113120","DOIUrl":"10.1016/j.jbiomech.2025.113120","url":null,"abstract":"<div><div>This study examined the effect of neural mode (i.e., static optimisation (SO) or Calibrated Electromyography-Informed Neuromusculoskeletal Modelling (CEINMS)) on model estimated muscle contributions to knee loading in individuals with anterior cruciate ligament reconstruction (ACLR) during side-step cutting. Eleven individuals with ACLR completed pre-planned sidestep cutting in a gait laboratory while their whole-body motions, body-ground reaction forces, and electromyography (EMG) from major knee-spanning muscles were acquired. Neuromusculoskeletal modelling simulations were performed using both SO and CEINMS methods to estimate muscle contributions to anteroposterior force, varus/valgus moments, and internal/external rotation moments at the knee. Both SO and CEINMS neural modes accurately predicted body-ground reaction forces. Moderate-to-strong coefficients of determination were found between CEINMS and SO estimates of muscle contributions to knee loads. Irrespective of neural mode, quadriceps were the dominant cause of anterior force, valgus moment, and external rotation moment at the knee, while hamstrings contributed most to the knee’s posterior force and internal rotation moment. Non-knee-spanning muscles also contributed to knee loads, with small between-mode differences in these contributions. In conclusion, both neural modes well predicted whole-body mechanics (i.e., body-ground reaction forces) and differences between neural modes became more pronounced as the focus of analysis moved from general (e.g., net body-ground loads) to knee-specific mechanics.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"195 ","pages":"Article 113120"},"PeriodicalIF":2.4,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145733608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Uncertainty estimation in marker-based motion capture of the tennis serve 基于标记的网球发球动作捕捉中的不确定性估计

IF 2.4 3区医学 Q3 BIOPHYSICS

Journal of biomechanics

Pub Date : 2025-12-10 DOI: 10.1016/j.jbiomech.2025.113119

Simon Ozan , Loïc Fourel , Pierre Touzard , Richard Kulpa , Caroline Martin

Marker-based motion capture (MoCap) systems are widely used to analyse human movement. However, they are affected by measurement uncertainties, particularly marker placement errors (MPE) and soft tissue artefacts (STA). Here, we quantify the individual and combined effects of these two sources of uncertainty on joint angles and angular velocities in the case of the tennis serve. A Monte-Carlo approach was used to simulate 3000 perturbed marker trajectories for each uncertainty source and their combination. We applied a random offset for MPE, while sinusoidal perturbations were used to simulate for STA. The resulting joint kinematics were compared across all degrees of freedom. Confidence intervals (5–95 %), root mean square deviation (RMSD) and Minimal Detectable Changes (MDC) were calculated for key biomechanical variables. Results showed that STA predominantly affected angular velocities, while MPE had a greater impact on joint angles. The combined simulation consistently produced the largest variability, with mean confidence intervals ranging from 5.1° to 30.8° for joint angles and from 70.5°.s⁻¹ to 248.5°.s⁻¹ for joint angular velocities, and RMSD values ranging from 1.6° to 8.4° for joint angles and from 16.8°.s⁻¹ to 68.0°.s⁻¹ for joint angular velocities. To our knowledge, this is the first quantification of MPE and STA effects on ballistic movement kinematics. These results provide critical reference values, enabling more accurate comparisons across subjects and studies while accounting for measurement uncertainties.

基于标记的动作捕捉（MoCap）系统被广泛用于分析人体运动。然而，它们受到测量不确定性的影响，特别是标记放置误差（MPE）和软组织伪影（STA）。在这里，我们量化了在网球发球的情况下，这两个不确定性来源对关节角度和角速度的单独和综合影响。采用蒙特卡罗方法模拟了每个不确定性源及其组合的3000个扰动标记轨迹。我们对MPE应用随机偏移，而正弦扰动用于模拟STA。所得的关节运动学在所有自由度上进行了比较。计算关键生物力学变量的置信区间（5 - 95%）、均方根偏差（RMSD）和最小可检测变化（MDC）。结果表明：STA对角速度的影响较大，而MPE对关节角的影响较大。联合模拟始终产生最大的变异性，关节角度的平均置信区间为5.1°至30.8°，平均置信区间为70.5°。S−1 ~ 248.5°。关节角速度为s−1，关节角的RMSD值为1.6°至8.4°，RMSD值为16.8°。S−1 ~ 68.0°。S−1表示关节角速度。据我们所知，这是第一次量化MPE和STA对弹道运动运动学的影响。这些结果提供了关键的参考值，在考虑测量不确定性的同时，可以更准确地进行跨主题和研究的比较。

{"title":"Uncertainty estimation in marker-based motion capture of the tennis serve","authors":"Simon Ozan , Loïc Fourel , Pierre Touzard , Richard Kulpa , Caroline Martin","doi":"10.1016/j.jbiomech.2025.113119","DOIUrl":"10.1016/j.jbiomech.2025.113119","url":null,"abstract":"<div><div>Marker-based motion capture (MoCap) systems are widely used to analyse human movement. However, they are affected by measurement uncertainties, particularly marker placement errors (MPE) and soft tissue artefacts (STA). Here, we quantify the individual and combined effects of these two sources of uncertainty on joint angles and angular velocities in the case of the tennis serve. A Monte-Carlo approach was used to simulate 3000 perturbed marker trajectories for each uncertainty source and their combination. We applied a random offset for MPE, while sinusoidal perturbations were used to simulate for STA. The resulting joint kinematics were compared across all degrees of freedom. Confidence intervals (5–95 %), root mean square deviation (RMSD) and Minimal Detectable Changes (MDC) were calculated for key biomechanical variables. Results showed that STA predominantly affected angular velocities, while MPE had a greater impact on joint angles. The combined simulation consistently produced the largest variability, with mean confidence intervals ranging from 5.1° to 30.8° for joint angles and from 70.5°.s<sup>−1</sup> to 248.5°.s<sup>−1</sup> for joint angular velocities, and RMSD values ranging from 1.6° to 8.4° for joint angles and from 16.8°.s<sup>−1</sup> to 68.0°.s<sup>−1</sup> for joint angular velocities. To our knowledge, this is the first quantification of MPE and STA effects on ballistic movement kinematics. These results provide critical reference values, enabling more accurate comparisons across subjects and studies while accounting for measurement uncertainties.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"195 ","pages":"Article 113119"},"PeriodicalIF":2.4,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145786889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of Hip-Shoulder separation on pitch velocity in college baseball pitchers 髋肩分离对大学棒球投手投球速度的影响

IF 2.4 3区医学 Q3 BIOPHYSICS

Journal of biomechanics

Pub Date : 2025-12-09 DOI: 10.1016/j.jbiomech.2025.113117

Ian P. Jump , Benjamin G. Lerch , Ryan M. Zappa , Gabrielle N. Pfund , Kevin A. Giordano , Gretchen D. Oliver

Pitch velocity is a highly valued attribute in baseball pitching, owing to its positive influence on performance outcomes. One variable theorized to contribute to pitch velocity is hip-shoulder separation; however, limited research has examined this relationship. The purpose of this study was to investigate the connection between hip-shoulder separation and pitch velocity. A total of 335 NCAA Division 1 pitchers were analyzed (1.88 ± .06 m; 91.6 ± 10.0 kg; 223 right-handed pitchers, 112 left-handed pitchers). In-game kinematics were collected using a markerless motion capture system. Statistical parametric mapping regression revealed a significant positive relationship between hip-shoulder separation and pitch velocity from 83-90 % between peak knee height and ball release, p = 0.04; peak r = 0.16), which was between foot contact and maximum external rotation. In addition, a multilevel model demonstrated a small, positive relationship between hip-shoulder separation at foot contact and pitch velocity, with high individual variability. These findings suggest a weak, positive relationship between hip-shoulder separation and pitch velocity, though the within-pitcher relationship was not consistent across all pitchers. Consequently, it can be inferred that increased hip-shoulder separation may contribute to higher pitch velocities, but due to significant individual differences, performance assessments should be conducted on a case-by-case basis, with sufficient data collection for each athlete.

投球速度是棒球投球中一个非常重要的属性，因为它对比赛结果有积极的影响。理论上，影响俯仰速度的一个变量是髋肩分离；然而，有限的研究已经检验了这种关系。本研究的目的是探讨髋肩分离与投球速度之间的关系。共对335名NCAA一级联赛投手进行了分析(1.88±。06 m;91.6±10.0 kg；223名右投手，112名左投手)。使用无标记动作捕捉系统收集游戏内运动学。统计参数映射回归显示，髋肩分离与投球速度之间的正相关关系在峰值膝部高度与球释放之间的83% ~ 90%之间，p = 0.04；峰值r = 0.16)，在足部接触和最大外旋之间。此外，一个多层次模型表明，足部接触时的髋肩分离与投球速度之间存在很小的正相关关系，具有很高的个体变异性。这些发现表明，髋肩分离与投球速度之间存在微弱的正相关关系，尽管投手内部的关系并不适用于所有投手。因此，可以推断，增加髋肩分离可能有助于提高投球速度，但由于显著的个体差异，表现评估应在个案的基础上进行，并为每个运动员收集足够的数据。

{"title":"Influence of Hip-Shoulder separation on pitch velocity in college baseball pitchers","authors":"Ian P. Jump , Benjamin G. Lerch , Ryan M. Zappa , Gabrielle N. Pfund , Kevin A. Giordano , Gretchen D. Oliver","doi":"10.1016/j.jbiomech.2025.113117","DOIUrl":"10.1016/j.jbiomech.2025.113117","url":null,"abstract":"<div><div>Pitch velocity is a highly valued attribute in baseball pitching, owing to its positive influence on performance outcomes. One variable theorized to contribute to pitch velocity is hip-shoulder separation; however, limited research has examined this relationship. The purpose of this study was to investigate the connection between hip-shoulder separation and pitch velocity. A total of 335 NCAA Division 1 pitchers were analyzed (1.88 ± .06 m; 91.6 ± 10.0 kg; 223 right-handed pitchers, 112 left-handed pitchers). In-game kinematics were collected using a markerless motion capture system. Statistical parametric mapping regression revealed a significant positive relationship between hip-shoulder separation and pitch velocity from 83-90 % between peak knee height and ball release, p = 0.04; peak r = 0.16), which was between foot contact and maximum external rotation. In addition, a multilevel model demonstrated a small, positive relationship between hip-shoulder separation at foot contact and pitch velocity, with high individual variability. These findings suggest a weak, positive relationship between hip-shoulder separation and pitch velocity, though the within-pitcher relationship was not consistent across all pitchers. Consequently, it can be inferred that increased hip-shoulder separation may contribute to higher pitch velocities, but due to significant individual differences, performance assessments should be conducted on a case-by-case basis, with sufficient data collection for each athlete.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"195 ","pages":"Article 113117"},"PeriodicalIF":2.4,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145733610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Three-dimensional hip and knee loading during the Copenhagen adductor exercise 哥本哈根内收肌运动中的三维髋关节和膝关节负荷。

IF 2.4 3区医学 Q3 BIOPHYSICS

Journal of biomechanics

Pub Date : 2025-12-08 DOI: 10.1016/j.jbiomech.2025.113116

Torstein E. Dæhlin , Daryna Dmytriieva , Emma Rutherford , Loren Z.F. Chiu

The Copenhagen adductor exercise (CAE) is used for groin muscle strengthening. While these muscles primarily act in the frontal plane, the hip adductor muscles may also act in the sagittal and transverse planes. Therefore, the CAE likely imposes three-dimensional (3D) muscular demands at both the hip and knee. This study aimed to quantify the 3D hip and knee joint loading during variations of the CAE. Eleven men and 13 women performed the exercise with the support stand at the knee, ankle, and midway between the knee and ankle. Ground reaction forces under the stand and reflective markers trajectories were recorded to calculate hip and knee net joint moments (NJM). Hip adductor NJM was largest for the ankle support (1.54 ± 0.23 Nm·kg⁻¹) and smallest for the knee support (0.93 ± 0.16 Nm·kg⁻¹; P < 0.001). Most participants had a hip extensor NJM, that was also greater for more distal support locations (Δ_ankle-mid = −0.10 ± 0.21 Nm·kg⁻¹; Δ_ankle-knee = −0.20 ± 0.27 Nm·kg⁻¹; P < 0.001). Support locations distal to the knee had knee adductor and flexor NJM. The hip and knee sagittal plane NJMs were strongly correlated with transverse plane thigh (r = 0.97–0.98, P < 0.017) and shank (r = 0.89–0.93, P < 0.017) orientations, respectively. Medial thigh rotation was associated with a hip flexor NJM while lateral thigh rotation was associated with a hip extensor NJM. CAE requires frontal and sagittal plane muscle efforts at the hip and knee, which are greater for more distal support locations.

哥本哈根内收肌运动（CAE）用于腹股沟肌肉的强化。虽然这些肌肉主要作用于额平面，但髋内收肌也可能作用于矢状面和横平面。因此，CAE可能会对髋关节和膝关节施加三维（3D）肌肉需求。本研究旨在量化CAE变化期间髋关节和膝关节的三维负荷。11名男性和13名女性在膝盖、脚踝以及膝盖和脚踝之间的中间位置放置支撑架。记录支架下的地面反作用力和反射标记物轨迹，计算髋关节和膝关节关节力矩（NJM）。髋关节内收肌NJM对踝关节支撑作用最大（1.54±0.23 Nm·kg-1），对膝关节支撑作用最小（0.93±0.16 Nm·kg-1, P < 0.001）。大多数参与者都有髋关节伸肌NJM，在更远的支持位置也更大（Δankle-mid = -0.10±0.21 Nm·kg-1； Δankle-knee = -0.20±0.27 Nm·kg-1; P < 0.001）。膝关节远端支撑部位有膝内收肌和屈肌NJM。髋、膝矢状面NJMs分别与横切面大腿方向（r = 0.97-0.98, P < 0.017）和小腿方向（r = 0.89-0.93, P < 0.017）密切相关。大腿内侧旋转与髋关节屈肌NJM有关，而大腿外侧旋转与髋关节伸肌NJM有关。CAE需要髋关节和膝关节的额位和矢状面肌肉力量，对于更远的支持位置，这是更大的。

{"title":"Three-dimensional hip and knee loading during the Copenhagen adductor exercise","authors":"Torstein E. Dæhlin , Daryna Dmytriieva , Emma Rutherford , Loren Z.F. Chiu","doi":"10.1016/j.jbiomech.2025.113116","DOIUrl":"10.1016/j.jbiomech.2025.113116","url":null,"abstract":"<div><div>The Copenhagen adductor exercise (CAE) is used for groin muscle strengthening. While these muscles primarily act in the frontal plane, the hip adductor muscles may also act in the sagittal and transverse planes. Therefore, the CAE likely imposes three-dimensional (3D) muscular demands at both the hip and knee. This study aimed to quantify the 3D hip and knee joint loading during variations of the CAE. Eleven men and 13 women performed the exercise with the support stand at the knee, ankle, and midway between the knee and ankle. Ground reaction forces under the stand and reflective markers trajectories were recorded to calculate hip and knee net joint moments (NJM). Hip adductor NJM was largest for the ankle support (1.54 ± 0.23 Nm·kg<sup>−1</sup>) and smallest for the knee support (0.93 ± 0.16 Nm·kg<sup>−1</sup>; <em>P</em> < 0.001). Most participants had a hip extensor NJM, that was also greater for more distal support locations (Δ<sub>ankle-mid</sub> = −0.10 ± 0.21 Nm·kg<sup>−1</sup>; Δ<sub>ankle-knee</sub> = −0.20 ± 0.27 Nm·kg<sup>−1</sup>; <em>P</em> < 0.001). Support locations distal to the knee had knee adductor and flexor NJM. The hip and knee sagittal plane NJMs were strongly correlated with transverse plane thigh (<em>r</em> = 0.97–0.98, <em>P</em> < 0.017) and shank (<em>r</em> = 0.89–0.93, <em>P</em> < 0.017) orientations, respectively. Medial thigh rotation was associated with a hip flexor NJM while lateral thigh rotation was associated with a hip extensor NJM. CAE requires frontal and sagittal plane muscle efforts at the hip and knee, which are greater for more distal support locations.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"195 ","pages":"Article 113116"},"PeriodicalIF":2.4,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145723524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An artificial neural network to estimate detailed active–passive spinal loads during static lifting activities for a standardized anthropometry 一个人工神经网络，以估计详细的主动被动脊柱负荷在静态举重活动的标准化人体测量

IF 2.4 3区医学 Q3 BIOPHYSICS

Journal of biomechanics

Pub Date : 2025-12-08 DOI: 10.1016/j.jbiomech.2025.113115

Hassan Mohammadi, Navid Arjmand

Numerous musculoskeletal models have been developed to estimate spine loads for use in occupational risk assessment programs. These models typically oversimplify the complex intervertebral joints by representing them as pivots, thereby failing to estimate load sharing among the intervertebral discs, facet joints, ligaments and disc annulus/nucleus. Our coupled musculoskeletal-finite-element model integrates both the musculature and detailed geometry of the passive spine to yield comprehensive predictions for a standardized anthropometry. However, this model is time/skill-intensive. We aimed to train an artificial neural network (ANN) to replicate the outputs of this model during sagittally-symmetric static lifting tasks. A training dataset was generated by simulating 500 tasks using the model with different hand-loads (up to 20 kg) and positions (up to 30 cm horizontal distance from the shoulders), trunk flexions (up to 80°), and lumbopelvic ratios (3 levels for each flexion angle). The outputs included T12-S1 intradiscal pressure, maximum annulus principal stress, disc compressive/shear loads, resultant facet joint forces, resultant force of all posterior ligaments, and force in trunk muscles. The ANN successfully mapped the model inputs to its 83 outputs with satisfactory predictive accuracy; normalized-root-mean-squared-errors < 3 % and R² > 0.98. Bland-Altman analyses indicated no consistent bias between the ANN and model predictions, with a narrow 95 % limits of agreement across all outputs, e.g., 0.1 MPa for L4-L5 intradiscal pressure. This ANN is a fast practical tool for risk assessment applications. It can also be used to provide realistic trunk muscle-driven loading scenarios for passive finite element spine models in biomechanical evaluations.

许多肌肉骨骼模型已经开发估计脊柱负荷用于职业风险评估程序。这些模型通常通过将复杂的椎间关节表示为枢轴来过度简化它们，从而无法估计椎间盘、小关节、韧带和椎间盘环/核之间的负荷分担。我们的耦合肌肉-骨骼-有限元模型集成了被动脊柱的肌肉组织和详细几何形状，从而为标准化的人体测量学提供全面的预测。然而，这种模式是时间/技能密集型的。我们的目标是训练一个人工神经网络（ANN）来复制该模型在矢状对称静态提升任务中的输出。通过使用该模型模拟500个任务，生成训练数据集，这些任务具有不同的手负荷（高达20公斤）和位置（距离肩部高达30厘米的水平距离），躯干屈曲（高达80°）和腰骨盆比例（每个屈曲角度有3个级别）。输出包括T12-S1椎间盘内压力、最大环主应力、椎间盘压缩/剪切载荷、关节突关节合力、所有后韧带合力和躯干肌肉力。人工神经网络成功地将模型输入映射到它的83个输出，并具有令人满意的预测精度；标准化均方根误差<； 3%, R2 > 0.98。Bland-Altman分析表明，人工神经网络和模型预测之间没有一致的偏差，所有输出的一致性限制为95%，例如L4-L5椎间盘内压力为0.1 MPa。该人工神经网络是一种快速实用的风险评估工具。它也可以用于提供真实的躯干肌肉驱动的加载场景被动有限元脊柱模型在生物力学评估。

{"title":"An artificial neural network to estimate detailed active–passive spinal loads during static lifting activities for a standardized anthropometry","authors":"Hassan Mohammadi, Navid Arjmand","doi":"10.1016/j.jbiomech.2025.113115","DOIUrl":"10.1016/j.jbiomech.2025.113115","url":null,"abstract":"<div><div>Numerous musculoskeletal models have been developed to estimate spine loads for use in occupational risk assessment programs. These models typically oversimplify the complex intervertebral joints by representing them as pivots, thereby failing to estimate load sharing among the intervertebral discs, facet joints, ligaments and disc annulus/nucleus. Our coupled musculoskeletal-finite-element model integrates both the musculature and detailed geometry of the passive spine to yield comprehensive predictions for a standardized anthropometry. However, this model is time/skill-intensive. We aimed to train an artificial neural network (ANN) to replicate the outputs of this model during sagittally-symmetric static lifting tasks. A training dataset was generated by simulating 500 tasks using the model with different hand-loads (up to 20 kg) and positions (up to 30 cm horizontal distance from the shoulders), trunk flexions (up to 80°), and lumbopelvic ratios (3 levels for each flexion angle). The outputs included T12-S1 intradiscal pressure, maximum annulus principal stress, disc compressive/shear loads, resultant facet joint forces, resultant force of all posterior ligaments, and force in trunk muscles. The ANN successfully mapped the model inputs to its 83 outputs with satisfactory predictive accuracy; normalized-root-mean-squared-errors < 3 % and R<sup>2</sup> > 0.98. Bland-Altman analyses indicated no consistent bias between the ANN and model predictions, with a narrow 95 % limits of agreement across all outputs, e.g., 0.1 MPa for L4-L5 intradiscal pressure. This ANN is a fast practical tool for risk assessment applications. It can also be used to provide realistic trunk muscle-driven loading scenarios for passive finite element spine models in biomechanical evaluations.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"195 ","pages":"Article 113115"},"PeriodicalIF":2.4,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145733606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing sensitivity of predictive shoulder simulations to uncertain soft tissue properties 评估预测肩部模拟对不确定软组织特性的敏感性

IF 2.4 3区医学 Q3 BIOPHYSICS

Journal of biomechanics

Pub Date : 2025-12-08 DOI: 10.1016/j.jbiomech.2025.113114

Morgan J. Dalman, Katherine R. Saul

Accurate modeling of glenohumeral joint mechanics requires reliable representations of passive structures such as ligaments and articular cartilage, yet these tissue properties are un-available in vivo on a subject-specific basis. This study evaluated how variability in ligament and cartilage properties propagates to joint-level outcomes. Using a validated musculoskeletal shoulder model and two Monte Carlo simulation frameworks, we independently varied glenohumeral ligament (stiffness and slack length) and cartilage (elastic modulus and thickness) parameters to predict secondary kinematics and joint contact mechanics during scaption. Regression analysis revealed that ligament slack length, particularly for the anterior and middle glenohumeral ligaments (A-IGHL and MGHL), had the most significant influence across outcomes. Articular cartilage properties also contributed significantly to contact mechanics, reinforcing their role as key contributors to load distribution. These findings are especially relevant for modeling pathological conditions such as osteoarthritis and surgical intervention such as joint replacement and ligament reconstructions, where cartilage and ligament structure and properties are altered. This work underscores the importance of accounting for soft tissue variability in subject-specific shoulder simulations and highlights targets for advancing in vivo characterization methods.

盂肱关节力学的精确建模需要可靠的被动结构表征，如韧带和关节软骨，然而这些组织特性在个体体内是不可用的。本研究评估了韧带和软骨特性的可变性如何传播到关节水平的结果。使用一个经过验证的肌肉骨骼肩部模型和两个蒙特卡罗模拟框架，我们独立地改变肩关节韧带（刚度和松弛长度）和软骨（弹性模量和厚度）参数，以预测截肢过程中的二次运动学和关节接触力学。回归分析显示，韧带松弛长度，特别是前和中盂肱韧带（A-IGHL和MGHL），对所有结果的影响最为显著。关节软骨的特性也对接触力学有重要影响，加强了它们作为载荷分配的关键贡献者的作用。这些发现对于骨关节炎和手术干预（如关节置换术和韧带重建）等病理条件的建模尤其相关，其中软骨和韧带的结构和特性被改变。这项工作强调了在特定受试者肩部模拟中考虑软组织变异性的重要性，并强调了推进体内表征方法的目标。

{"title":"Assessing sensitivity of predictive shoulder simulations to uncertain soft tissue properties","authors":"Morgan J. Dalman, Katherine R. Saul","doi":"10.1016/j.jbiomech.2025.113114","DOIUrl":"10.1016/j.jbiomech.2025.113114","url":null,"abstract":"<div><div>Accurate modeling of glenohumeral joint mechanics requires reliable representations of passive structures such as ligaments and articular cartilage, yet these tissue properties are un-available <em>in vivo</em> on a subject-specific basis. This study evaluated how variability in ligament and cartilage properties propagates to joint-level outcomes. Using a validated musculoskeletal shoulder model and two Monte Carlo simulation frameworks, we independently varied glenohumeral ligament (stiffness and slack length) and cartilage (elastic modulus and thickness) parameters to predict secondary kinematics and joint contact mechanics during scaption. Regression analysis revealed that ligament slack length, particularly for the anterior and middle glenohumeral ligaments (A-IGHL and MGHL), had the most significant influence across outcomes. Articular cartilage properties also contributed significantly to contact mechanics, reinforcing their role as key contributors to load distribution. These findings are especially relevant for modeling pathological conditions such as osteoarthritis and surgical intervention such as joint replacement and ligament reconstructions, where cartilage and ligament structure and properties are altered. This work underscores the importance of accounting for soft tissue variability in subject-specific shoulder simulations and highlights targets for advancing <em>in vivo</em> characterization methods.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"195 ","pages":"Article 113114"},"PeriodicalIF":2.4,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145734025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of component offset on acromion and scapular spine strains following reverse total shoulder arthroplasty: An ex-vivo shoulder motion study 反向全肩关节置换术后构件偏移对肩峰和肩胛骨拉伤的影响：一项离体肩关节运动研究。

IF 2.4 3区医学 Q3 BIOPHYSICS

Journal of biomechanics

Pub Date : 2025-12-06 DOI: 10.1016/j.jbiomech.2025.113112

David T. Axford , Robert Potra , Richard Appleyard , Janos Tomka , Antonio Arenas-Miquelez , Desmond J. Bokor , Louis M. Ferreira , Sumit Raniga

The effects of component offset in reverse total shoulder arthroplasty (rTSA) on acromion and scapular spine strains are not well understood, and no comparison of strain patterns between the native and implanted shoulder exists. This study investigated the effects of humerus distalization, humerus lateralization, glenosphere lateralization, and humerus-to-glenosphere lateralization ratio in rTSA on acromion and scapular spine strains during simulated unconstrained shoulder motion and compared the observed strain patterns to the native condition. Seven cadaveric specimens were tested on a shoulder simulator which performed scapular plane abduction and internal-external rotation. Maximum principal strain was measured in four clinically relevant regions according to the Levy classification system using strain gauge rosettes. Overall, rTSA conditions had higher strains than the native condition at low elevation (p < 0.05) but not at high elevation. During scapular plane abduction, strain peaked at low elevation for all reverse conditions, but at high elevation angles in the native condition. Strain increased significantly with humerus distalization in Levy 3A (p = 0.038), while strain decreased significantly in all regions with humerus lateralization (p ≤ 0.049). Isolated glenosphere lateralization had no effect on scapula strains (p ≥ 0.162) while humerus-sided lateralization resulted in significantly less strain than combined humerus and glenosphere lateralization (p ≤ 0.015). RTSA alters the strain patterns on the acromion and scapular spine from those observed in the native shoulder. In addition, component offset had significant effects on scapula strains demonstrating that implant configuration likely has an influence on the occurrence of acromion and scapular spine fractures.

逆行全肩关节置换术（rTSA）中构件偏移对肩峰和肩胛骨应变的影响尚不清楚，也没有对原生肩关节和植入肩关节的应变模式进行比较。本研究研究了rTSA中肱骨远端化、肱骨侧化、关节盂侧化和肱骨-关节盂侧化比例对模拟无约束肩部运动中肩峰和肩胛骨应变的影响，并将观察到的应变模式与自然状态进行了比较。7具尸体标本在肩胛骨平面外展和内外旋转的肩部模拟器上进行了测试。最大主应变测量在四个临床相关区域根据列维分类系统使用应变计玫瑰花。总体而言，低海拔rTSA条件下的菌株数量高于自然条件(p

{"title":"The effect of component offset on acromion and scapular spine strains following reverse total shoulder arthroplasty: An ex-vivo shoulder motion study","authors":"David T. Axford , Robert Potra , Richard Appleyard , Janos Tomka , Antonio Arenas-Miquelez , Desmond J. Bokor , Louis M. Ferreira , Sumit Raniga","doi":"10.1016/j.jbiomech.2025.113112","DOIUrl":"10.1016/j.jbiomech.2025.113112","url":null,"abstract":"<div><div>The effects of component offset in reverse total shoulder arthroplasty (rTSA) on acromion and scapular spine strains are not well understood, and no comparison of strain patterns between the native and implanted shoulder exists. This study investigated the effects of humerus distalization, humerus lateralization, glenosphere lateralization, and humerus-to-glenosphere lateralization ratio in rTSA on acromion and scapular spine strains during simulated unconstrained shoulder motion and compared the observed strain patterns to the native condition. Seven cadaveric specimens were tested on a shoulder simulator which performed scapular plane abduction and internal-external rotation. Maximum principal strain was measured in four clinically relevant regions according to the Levy classification system using strain gauge rosettes. Overall, rTSA conditions had higher strains than the native condition at low elevation (p < 0.05) but not at high elevation. During scapular plane abduction, strain peaked at low elevation for all reverse conditions, but at high elevation angles in the native condition. Strain increased significantly with humerus distalization in Levy 3A (p = 0.038), while strain decreased significantly in all regions with humerus lateralization (p ≤ 0.049). Isolated glenosphere lateralization had no effect on scapula strains (p ≥ 0.162) while humerus-sided lateralization resulted in significantly less strain than combined humerus and glenosphere lateralization (p ≤ 0.015). RTSA alters the strain patterns on the acromion and scapular spine from those observed in the native shoulder. In addition, component offset had significant effects on scapula strains demonstrating that implant configuration likely has an influence on the occurrence of acromion and scapular spine fractures.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"195 ","pages":"Article 113112"},"PeriodicalIF":2.4,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145714471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of vibration frequency, amplitude, and direction on human gait metrics 振动频率、振幅和方向对人体步态测量的影响

IF 2.4 3区医学 Q3 BIOPHYSICS

Journal of biomechanics

Pub Date : 2025-12-06 DOI: 10.1016/j.jbiomech.2025.113100

Flavia Marrone , Filippo Motta , Stefano Marelli , Manuela Galli , Marco Tarabini , Pierre Lemerle

The effect of vibrations on gait is a topic that has not been sufficiently analyzed. Thirty-one volunteers underwent 50 walking trials on a modified treadmill with three degrees of freedom including normal walking and walking in the presence of sinusoidal roll, pitch, and vertical vibration. A full factorial design of experiments was adopted, using two vibration amplitudes (4 or 8 cm for linear displacements, 4° or 8° for angular oscillations), four frequencies (0.25, 0.5, 0.7, and 1 Hz), and two walking speeds (0.7 or 1 m/s). A significant alteration of all the gait metrics was found in the presence of vibration, but the step width and cadence resulted in the most affected. A combined effect of all factors was found, with the major impact on gait in the case of rotational vibration, mainly in the case of roll, at higher amplitude and frequencies. Understanding the most detrimental vibration conditions contributes to updating the ISO standard for whole-body vibration considering exposed walking workers.

振动对步态的影响是一个尚未得到充分分析的话题。31名志愿者在改良的跑步机上进行了50次步行试验，试验有三个自由度，包括正常行走和在正弦滚动、俯仰和垂直振动的情况下行走。实验采用全因子设计，采用两种振动幅度（线性位移为4或8 cm，角振荡为4°或8°），四种频率（0.25、0.5、0.7和1 Hz）和两种行走速度（0.7或1 m/s）。在振动存在的情况下，所有步态指标都有显著的变化，但步宽和节奏受到的影响最大。发现了所有因素的综合影响，在旋转振动的情况下，主要是在滚动的情况下，在较高的振幅和频率下，对步态的影响最大。了解最有害的振动条件有助于更新考虑到暴露的步行工人的全身振动的ISO标准。

引用次数: 0

A distal-to-proximal shift is not a requisite mechanism for greater metabolic cost of walking in older adults 远端到近端移位并不是老年人行走代谢成本增加的必要机制

IF 2.4 3区医学 Q3 BIOPHYSICS

Journal of biomechanics

Pub Date : 2025-12-06 DOI: 10.1016/j.jbiomech.2025.113109

Jacob M. Thomas, Zoe H. Smith, Jane A. Kent, Katherine A. Boyer

A greater metabolic cost of walking (CoW) is well-documented in older compared with young adults and is likely a catalyst for age-related mobility loss. Proximal redistribution of joint work during gait has been suggested as a contributor to greater CoW in aging. However, evidence to support this link is limited. We collected overground gait kinematics and kinetics as well as metabolic data during a 7-minute treadmill walk (7MTW) in 15 young (30–40 years, 8F) and 40 older (70–80 years) adults. We then separated the older adults into two groups based on whether they did (O_R, n = 15 (5F)), or did not (O_NR, n = 25 (17F)), proximally redistribute joint work using a redistribution ratio (RR), where O_R had an RR > 0.79 (Young mean RR + 1 SD) and O_NR had an RR ≤ 0.79. Contrary to our hypothesis, CoW was not different between O_R (0.105 ± 0.019 ml·kg⁻¹·min⁻¹) and O_NR (0.106 ± 0.016 ml·kg⁻¹·min⁻¹), while moderate-to-large effects for CoW were observed for both O_NR (P = 0.035, d = 0.83) and O_R (P = 0.106, d = 0.70) when compared to young (0.089 ± 0.013 ml·kg⁻¹·min⁻¹). These results suggest that the distal-to-proximal shift does not explain the greater CoW in older adults and further that restoring a “youthful” gait pattern may not address the problem of a greater CoW in older adults. Group characteristics such as age or preferred walking speed did not differ between the O_R and O_NR, but O_R was comprised predominantly of male participants suggesting sex specific factors for the gait shift should be queried.

与年轻人相比，老年人行走的代谢成本（CoW）更高，这可能是与年龄相关的行动能力丧失的催化剂。步态过程中关节工作的近端再分配被认为是衰老过程中更大的CoW的一个因素。然而，支持这种联系的证据有限。我们收集了15名年轻人（30-40岁，8F）和40名老年人（70-80岁）在7分钟跑步机步行（7MTW）期间的地上步态运动学和动力学以及代谢数据。然后，我们根据老年人是否有（OR, n = 15 (5F)）或没有（ONR, n = 25 (17F)）将他们分为两组，使用再分配比（RR）对关节工作进行近端重新分配，其中OR的RR为0.79 (Young mean RR + 1 SD)，而ONR的RR≤0.79。与我们的假设相反，CoW在OR（0.105±0.019 ml·kg - 1·min - 1）和ONR（0.106±0.016 ml·kg - 1·min - 1）之间没有差异，而与年轻（0.089±0.013 ml·kg - 1·min - 1）相比，ONR （P = 0.035, d = 0.83）和OR （P = 0.106, d = 0.70）对CoW都有中等到较大的影响。这些结果表明，远端到近端移位并不能解释老年人更大的CoW，进一步说，恢复“年轻”的步态模式可能不能解决老年人更大的CoW的问题。组特征，如年龄或首选步行速度在or和ONR之间没有差异，但or主要由男性参与者组成，这表明步态变化的性别特定因素应该被询问。

{"title":"A distal-to-proximal shift is not a requisite mechanism for greater metabolic cost of walking in older adults","authors":"Jacob M. Thomas, Zoe H. Smith, Jane A. Kent, Katherine A. Boyer","doi":"10.1016/j.jbiomech.2025.113109","DOIUrl":"10.1016/j.jbiomech.2025.113109","url":null,"abstract":"<div><div>A greater metabolic cost of walking (CoW) is well-documented in older compared with young adults and is likely a catalyst for age-related mobility loss. Proximal redistribution of joint work during gait has been suggested as a contributor to greater CoW in aging. However, evidence to support this link is limited. We collected overground gait kinematics and kinetics as well as metabolic data during a 7-minute treadmill walk (7MTW) in 15 young (30–40 years, 8F) and 40 older (70–80 years) adults. We then separated the older adults into two groups based on whether they did (O<sub>R</sub>, n = 15 (5F)), or did not (O<sub>NR</sub>, n = 25 (17F)), proximally redistribute joint work using a redistribution ratio (RR), where O<sub>R</sub> had an RR > 0.79 (Young mean RR + 1 SD) and O<sub>NR</sub> had an RR ≤ 0.79. Contrary to our hypothesis, CoW was not different between O<sub>R</sub> (0.105 ± 0.019 ml·kg<sup>−1</sup>·min<sup>−1</sup>) and O<sub>NR</sub> (0.106 ± 0.016 ml·kg<sup>−1</sup>·min<sup>−1</sup>), while moderate-to-large effects for CoW were observed for both O<sub>NR</sub> (<em>P</em> = 0.035, <em>d</em> = 0.83) and O<sub>R</sub> (<em>P</em> = 0.106, <em>d</em> = 0.70) when compared to young (0.089 ± 0.013 ml·kg<sup>−1</sup>·min<sup>−1</sup>). These results suggest that the distal-to-proximal shift does not explain the greater CoW in older adults and further that restoring a “youthful” gait pattern may not address the problem of a greater CoW in older adults. Group characteristics such as age or preferred walking speed did not differ between the O<sub>R</sub> and O<sub>NR,</sub> but O<sub>R</sub> was comprised predominantly of male participants suggesting sex specific factors for the gait shift should be queried.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"195 ","pages":"Article 113109"},"PeriodicalIF":2.4,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145734024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A novel pipeline using statistical parametric mapping for assessing differences in three- and four-dimensional computed tomography-derived arthrokinematics 一个新的管道使用统计参数映射来评估三维和四维计算机断层扫描衍生的关节运动学的差异

IF 2.4 3区医学 Q3 BIOPHYSICS

Journal of biomechanics

Pub Date : 2025-12-06 DOI: 10.1016/j.jbiomech.2025.113101

Taylor P. Trentadue , Andrew R. Thoreson , Thor E. Andreassen , Cesar Lopez , David R. Holmes III , Sanjeev Kakar , Shuai Leng , Kristin D. Zhao

Four-dimensional computed tomography (4DCT) can be used to quantify joint mechanics during dynamic tasks. Post-processing of 3D anatomical renderings permits calculation of joint surface arthrokinematics. Given the complexity and high dimensionality of arthrokinematic data, as well as variations in interparticipant morphology, sophisticated analytical techniques permitting comparisons between participants and throughout motion cycles are needed. Statistical parametric mapping (SPM) has been applied to biomechanical and imaging datasets to overcome this challenge; however, applications to 4DCT remain under-explored. The proposed pipeline is demonstrated at the distal radioulnar joint (DRUJ). This application explores relationships between wrist position (a continuous variable) and arthrokinematic interosseous proximities (a surface-based measure) in two contexts. Static-neutral CT data from 30 normative participants are used in the first application. Bilateral 4DCT pronosupination arcs from two participants with unilateral injury are included in the second application. A canonical joint was created using a multi-level, multi-object statistical shape model, on which the articular surface of interest was defined. Participant-specific joint surfaces were predicted from the canonical template via non-linear morphing. SPM regression and generalized linear models were used to explore relationships between wrist position, injury status, and interosseous proximities. The analysis captured position-related differences in interosseous proximities, demonstrating the application of this pipeline to 3DCT- and 4DCT-derived arthrokinematics. As hypothesized, increased pronation was associated with increased proximities at the sigmoid notch volar margin. The proposed pipeline can be applied to other joints, functional tasks, experimental conditions, or injury states to quantify how arthrokinematics are related to both continuous and categorical variables.

四维计算机断层扫描（4DCT）可用于量化动态任务中的关节力学。三维解剖效果图的后处理允许关节表面关节运动学的计算。考虑到关节运动学数据的复杂性和高维性，以及参与者之间形态的变化，需要复杂的分析技术来比较参与者之间和整个运动周期。统计参数映射（SPM）已应用于生物力学和成像数据集，以克服这一挑战；然而，4DCT的应用仍未得到充分探索。在远端尺桡关节（DRUJ）处展示了拟议的管道。本应用在两种情况下探讨了手腕位置（一个连续变量）和关节运动学骨间距离（一个基于表面的测量）之间的关系。在第一次应用中使用了来自30个规范参与者的静态中立CT数据。来自两名单侧损伤参与者的双侧4DCT旋前弧线包括在第二次应用中。利用多层次、多目标的统计形状模型创建典型关节，并在该模型上定义感兴趣的关节面。通过非线性变形从规范模板中预测参与者特定的关节面。SPM回归和广义线性模型用于探讨腕部位置、损伤状态和骨间距离之间的关系。该分析捕获了骨间邻近部位的位置相关差异，展示了该管道在3DCT和4dct衍生关节运动学中的应用。正如假设的那样，旋前增加与乙状突切迹掌侧缘近端增加有关。所提出的管道可以应用于其他关节、功能任务、实验条件或损伤状态，以量化关节运动学如何与连续变量和分类变量相关。

{"title":"A novel pipeline using statistical parametric mapping for assessing differences in three- and four-dimensional computed tomography-derived arthrokinematics","authors":"Taylor P. Trentadue , Andrew R. Thoreson , Thor E. Andreassen , Cesar Lopez , David R. Holmes III , Sanjeev Kakar , Shuai Leng , Kristin D. Zhao","doi":"10.1016/j.jbiomech.2025.113101","DOIUrl":"10.1016/j.jbiomech.2025.113101","url":null,"abstract":"<div><div>Four-dimensional computed tomography (4DCT) can be used to quantify joint mechanics during dynamic tasks. Post-processing of 3D anatomical renderings permits calculation of joint surface arthrokinematics. Given the complexity and high dimensionality of arthrokinematic data, as well as variations in interparticipant morphology, sophisticated analytical techniques permitting comparisons between participants and throughout motion cycles are needed. Statistical parametric mapping (SPM) has been applied to biomechanical and imaging datasets to overcome this challenge; however, applications to 4DCT remain under-explored. The proposed pipeline is demonstrated at the distal radioulnar joint (DRUJ). This application explores relationships between wrist position (a continuous variable) and arthrokinematic interosseous proximities (a surface-based measure) in two contexts. Static-neutral CT data from 30 normative participants are used in the first application. Bilateral 4DCT pronosupination arcs from two participants with unilateral injury are included in the second application. A canonical joint was created using a multi-level, multi-object statistical shape model, on which the articular surface of interest was defined. Participant-specific joint surfaces were predicted from the canonical template via non-linear morphing. SPM regression and generalized linear models were used to explore relationships between wrist position, injury status, and interosseous proximities. The analysis captured position-related differences in interosseous proximities, demonstrating the application of this pipeline to 3DCT- and 4DCT-derived arthrokinematics. As hypothesized, increased pronation was associated with increased proximities at the sigmoid notch volar margin. The proposed pipeline can be applied to other joints, functional tasks, experimental conditions, or injury states to quantify how arthrokinematics are related to both continuous and categorical variables.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"195 ","pages":"Article 113101"},"PeriodicalIF":2.4,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145786923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0