Journal of cellular biochemistry最新文献

RETRACTION: D. Yan, D. Chen, and H.-J. Im, “Fibroblast Growth Factor-2 Promotes Catabolism via FGFR1-Ras-Raf-MEK1/2-ERK1/2 Axis That Coordinates With the PKCδ Pathway in Human Articular Chondrocytes,” Journal of Cellular Biochemistry 113, no. 9 (2012): 2856-2865, https://doi.org/10.1002/jcb.24160.

The above article, published online on 5 April 2012 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals LLC. The retraction has occurred due to concerns related to the data presented in the article raised by the Office of Research Compliance at Rush University Medical Center following an investigation jointly conducted by Rush University and the Jesse Brown Veterans Affairs Medical Center (JBVAMC). Specifically, image elements of the experimental data in Figures 2, 4 A and 5 C were found to have been used by the same author(s) for publication elsewhere in a different scientific context. The corresponding author, Dr. Hee-Jeong Im Sampen, has been informed of the decision to retract but did not agree with it, as she is confident that any errors in the publication do not impact the reliability of the paper's findings. She also advised the editors that she stands ready to cooperate fully to make any necessary corrections. However, the article is retracted as the editors lost trust in the accuracy of the data and consider the conclusions invalid.

RETRACTION: T. Gong, X. Ning, Z. Deng, M. Liu, B. Zhou, X. Chen, S. Huang, Y. Xu, Z. Chen, and R. Luo, “Propofol-Induced miR-219-5p Inhibits Growth and Invasion of Hepatocellular Carcinoma Through Suppression of GPC3-Mediated Wnt/β-Catenin Signalling Activation,” Journal of Cellular Biochemistry 120, no. 10 (2019): 16934-16945, https://doi.org/10.1002/jcb.28952.

The above article, published online on 19 May 2019 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals LLC. The retraction has been agreed due to concerns raised by third parties on the data presented in the article. Specifically, multiple areas of overlap were detected within and across Figures 1D, 2E and 2F. The authors acknowledged that unintentional mistakes were made during figure compilation and collaborated on the investigation into the detected issues. Even though they provided the raw data underlying the study, verification of the material's accuracy proved challenging due to the time elapsed since publication. As full accuracy of the provided material could no longer be ascertained, the editors have decided to retract the article, as they consider the identified issues to undermine the reliability of the presented research. The authors agree with the decision of retraction acknowledging that the identified issues may impact the overall interpretation of the research findings.

RETRACTION: H. Zhang, C. Feng, M. Zhang, A. Zeng, L. Si, N. Yu, and M. Bai, “MiR-625-5p/PKM2 Negatively Regulates Melanoma Glycolysis State,” Journal of Cellular Biochemistry 120, no. 3 (2019): 2964–2972, https://doi.org/10.1002/jcb.26917.

The above article, published online on 30 November 2018 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals LLC. The authors requested a retraction of this manuscript stating that different cell lines were wrongly labelled and that the conclusions of this manuscript needed to be re-evaluated. Further investigation by the publisher revealed that the article mentions use of the non-verifiable/unknown normal skin cells HFE. Additional flaws and inconsistencies between results presented and experimental methods described were identified. Furthermore, the experimental methods were found to lack sufficient details or have unavailable supporting data, making the experiments not comprehensible nor reproducible to readers. Accordingly, the editors consider the conclusions of this article to be invalid.

EXPRESSION OF CONCERN: N. Kumar, S. Reddi, S. Devi, S. B. Mada, R. Kapila, and S. Kapila, “Nrf2 Dependent Antiaging Effect of Milk-derived Bioactive Peptide in Old Fibroblasts,” Journal of Cellular Biochemistry 120, no. 6 (2019): 9677-9691, https://doi.org/10.1002/jcb.28246.

This expression of concern is for the above article, published online on 28 December 2018 in Wiley Online Library (wileyonlinelibrary.com), and has been agreed between the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals LLC. The expression of concern has been agreed upon due to concerns raised by a third party regarding the data presented in the article. Specifically, several panels in Figure 1B were found to originate from the same biological sample, yet were used to present different treatment groups. Furthermore, some of these panels had been previously published by the same author group in a different scientific context. As the identified issues do not undermine the study's conclusions, the editors have decided to issue this expression of concern to inform and alert readers.

RETRACTION: Z. Zhao, T. Liang, and S. Feng, “Silencing of HAS2-AS1 Mediates PI3K/AKT Signaling Pathway to Inhibit Cell Proliferation, Migration, and Invasion in Glioma,” Journal of Cellular Biochemistry 120, no. 7 (2019): 11510-11516, https://doi.org/10.1002/jcb.28430.

The above article, published online on 20 February 2019 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals LLC. The retraction has been agreed due to concerns raised by third parties on the data presented in the article. Several flaws and inconsistencies between results presented and experimental methods described were found. Furthermore, image elements in Figure 4 were found to have been previously published in a different scientific context. Thus, the editors consider the conclusions of this article to be invalid. The authors have been informed of the decision of retraction but unavailable for a final confirmation.

EXPRESSION OF CONCERN: Q. Zheng, Y. Yang, X. Cui, D. Zhang, S. Liu, and Q. Yan, “AP1 Mediates uPA/uPAR Induced FUT4 Expression and Trophoblast Invasion,” Journal of Cellular Biochemistry 119, no. 8 (2018): 6442-6451, https://doi.org/10.1002/jcb.26648.

This Expression of Concern is for the above article, published online on 26 December 2017 in Wiley Online Library (wileyonlinelibrary.com), has been issued by agreement between the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals, LLC.

The Expression of Concern has been agreed due to concerns raised by third parties regarding the data presented in the article. Specifically, overlaps have been detected in the invasion assay images between the “uPAR+c-Fos siRNA” and “uPAR+TIIA” groups in Figure 5C. Further investigation by the publisher revealed additional overlaps in the migration assay images between the “uPAR+SP600125” and “uPAR+TIIA” groups in the same figure. The authors explained that these overlaps occurred due to errors during the figure assembly and provided revised images to correct the mistakes. However, the replacement images provided by the authors failed to reproduce the results of the originally published images. Consequently, the journal has decided to issue this Expression of Concern to inform and alert readers.

Defect in membrane repair contributes to the development of muscular dystrophies such as limb girdle muscular dystrophy (LGMD) type R2 or R12. Nevertheless, many other muscular dystrophies may also result from a defect in this process. Identifying these pathologies requires the development of specific methods to inflict sarcolemma damage on a large number of cells and rapidly analyze their response. We adapted a protocol hitherto used to study the behavior of cancer cells to mechanical constraint. This method is based on forcing the passage of cells through a thin needle, which induces shear stress. Due to size considerations, this method requires working with mononuclear muscle cells instead of myotubes or muscle fibers. Although functional sarcolemma repair was thought to be restricted to myotubes and muscle fibers, we show here that 24h-differentiated myoblasts express a complete machinery capable of addressing membrane damage. At this stage, muscle cells do not yet form myotubes, revealing that the membrane repair machinery is set up early throughout the differentiation process. When submitted to the shear-stress assay, these cells were observed to repair membrane damage in a Ca²⁺-dependent manner, as previously reported. We show that this technique is able to identify the absence of membrane resealing in muscle cells from patient suffering from LGMDR2. The proposed technique provides therefore a suitable method for identifying cellular dysregulations in membrane repair of dystrophic human muscle cells.