Zuzanna Bober, Sabina Galiniak, Dawid Leksa, Klaudia Dynarowicz, D. Aebisher, Elżbieta Ostańska, Anna Czmil, P. Bar, D. Bartusik-Aebisher, P. Tutka
Introduction. Cytisine, Cytisinum (C11H14N2O), is an organic chemical compound. Cytisine is heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. Aim. The aim of the study is to measure the influence of water on the form of drug in the magnetic field 1.5 Tesla. Material and methods. For this purpose, magnetic resonance imaging tests were performed to check the solubility of pure cytisine, Desmoxan tablets and Tabex capsules. Results. From a pharmacological point of view, both Desmoxan tablets and Tabex capsules should exert the same effect on the human body, this is due to the identical content of the active substance, in this case cytisine (1.5 mg). Conclusion. The differences in the results obtained may be related to additional excipients that contain medications, but it is believed that they should not have a negative impact on the action of the active substance.
{"title":"Cytisine parameters measured in the 1.5 Tesla magnetic field","authors":"Zuzanna Bober, Sabina Galiniak, Dawid Leksa, Klaudia Dynarowicz, D. Aebisher, Elżbieta Ostańska, Anna Czmil, P. Bar, D. Bartusik-Aebisher, P. Tutka","doi":"10.15584/ejcem.2020.1.3","DOIUrl":"https://doi.org/10.15584/ejcem.2020.1.3","url":null,"abstract":"Introduction. Cytisine, Cytisinum (C11H14N2O), is an organic chemical compound. Cytisine is heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. Aim. The aim of the study is to measure the influence of water on the form of drug in the magnetic field 1.5 Tesla. Material and methods. For this purpose, magnetic resonance imaging tests were performed to check the solubility of pure cytisine, Desmoxan tablets and Tabex capsules. Results. From a pharmacological point of view, both Desmoxan tablets and Tabex capsules should exert the same effect on the human body, this is due to the identical content of the active substance, in this case cytisine (1.5 mg). Conclusion. The differences in the results obtained may be related to additional excipients that contain medications, but it is believed that they should not have a negative impact on the action of the active substance.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72713812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Babayo, Oyebanji Azeez Akande, Y. Sabo, I. Abdullahi, A. Dangana
{"title":"Serosurvey and Cellular Immune Status of HTLV-1/2 and HIV Co-infections in Bauchi State, Nigeria","authors":"A. Babayo, Oyebanji Azeez Akande, Y. Sabo, I. Abdullahi, A. Dangana","doi":"10.15584/ejcem.2019.4.1","DOIUrl":"https://doi.org/10.15584/ejcem.2019.4.1","url":null,"abstract":"","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74737141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Mucha, Natalia Leksa, D. Aebisher, Sabina Galiniak, Seweryn Bartosz, Dawid Leksa, D. Bartusik-Aebisher
Dorota Bartusik-Aebisher acknowledges support from the National Center of Science NCN (New drug delivery systems-MRI study, Grant OPUS-13 number 2017/25/B/ST4/02481).
{"title":"Generation of retractive spine circuits in the process of vitamin B12 deficiency","authors":"P. Mucha, Natalia Leksa, D. Aebisher, Sabina Galiniak, Seweryn Bartosz, Dawid Leksa, D. Bartusik-Aebisher","doi":"10.15584/ejcem.2020.2.9","DOIUrl":"https://doi.org/10.15584/ejcem.2020.2.9","url":null,"abstract":"Dorota Bartusik-Aebisher acknowledges support from the National Center of Science NCN (New drug delivery systems-MRI study, Grant OPUS-13 number 2017/25/B/ST4/02481).","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75518652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maciej Superson, Katarzyna Szmyt, K. Szymanska, K. Walczak, Jeremi Wnorowski, Łukasz Zarębski
Introduction. Recently, monoclonal antibodies (mAbs) have become powerful human therapeutics in the diagnosis and treatment of many diseases. Drugs based on mAbs are approved for the treatment of cardiovascular, respiratory, hematology, autoimmunology, and oncology diseases. Aim. To present the current state of knowledge about the application of mAbs in the therapy of various diseases such as cancer, autoimmune and Alzheimer’s diseases. Material and methods. We conducted a thorough review of the scientific literature from the following databases: EBSCO, PubMed, Science Direct, and Springer Link. Results. Currently, the Food and Drug Administration (FDA) has approved more than 50 therapeutic mAbs which are applied in various clinical trials. Action of mAb are based on various mechanisms, including directly targeting the cells, modifying the host response, recognizing and degrading molecules as well as delivering cytotoxic moieties. Conclusion. Despite some limitations including side effects, and therapeutic challenges, monoclonal antibodies are an attractive option for the development of new therapies and molecular drug targets against a wide range of common diseases due to their specificity and flexibility. MAbs are considered as a great hope for medicine, and effective and safe drugs in the treatment of various diseases.
{"title":"Clinical application of monoclonal antibodies in targeted therapy","authors":"Maciej Superson, Katarzyna Szmyt, K. Szymanska, K. Walczak, Jeremi Wnorowski, Łukasz Zarębski","doi":"10.15584/ejcem.2019.4.9","DOIUrl":"https://doi.org/10.15584/ejcem.2019.4.9","url":null,"abstract":"Introduction. Recently, monoclonal antibodies (mAbs) have become powerful human therapeutics in the diagnosis and treatment of many diseases. Drugs based on mAbs are approved for the treatment of cardiovascular, respiratory, hematology, autoimmunology, and oncology diseases. Aim. To present the current state of knowledge about the application of mAbs in the therapy of various diseases such as cancer, autoimmune and Alzheimer’s diseases. Material and methods. We conducted a thorough review of the scientific literature from the following databases: EBSCO, PubMed, Science Direct, and Springer Link. Results. Currently, the Food and Drug Administration (FDA) has approved more than 50 therapeutic mAbs which are applied in various clinical trials. Action of mAb are based on various mechanisms, including directly targeting the cells, modifying the host response, recognizing and degrading molecules as well as delivering cytotoxic moieties. Conclusion. Despite some limitations including side effects, and therapeutic challenges, monoclonal antibodies are an attractive option for the development of new therapies and molecular drug targets against a wide range of common diseases due to their specificity and flexibility. MAbs are considered as a great hope for medicine, and effective and safe drugs in the treatment of various diseases.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88823269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Osuchowski, D. Aebisher, Sabina Galiniak, D. Bartusik-Aebisher, E. Kaznowska
Dorota Bartusik-Aebisher acknowledges support from the National Center of Science NCN (New drug delivery systems-MRI study, Grant OPUS-13 number 2017/25/B/ST4/02481).
{"title":"Multiparametric MRI and other imaging methods suitable to stage prostate carcinoma","authors":"M. Osuchowski, D. Aebisher, Sabina Galiniak, D. Bartusik-Aebisher, E. Kaznowska","doi":"10.15584/ejcem.2019.4.7","DOIUrl":"https://doi.org/10.15584/ejcem.2019.4.7","url":null,"abstract":"Dorota Bartusik-Aebisher acknowledges support from the National Center of Science NCN (New drug delivery systems-MRI study, Grant OPUS-13 number 2017/25/B/ST4/02481).","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86399338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.15584/ejcem.2020.3.11
F. Dilek, Furkan Tosun, A. Atay, O. Dilek
Introduction. Sister Mary Joseph nodule (SMJN) is a metastasis that can occur in the umbilical region due to many tumors in the abdomen. Most of the cases are of gastrointestinal system origin and are often an indicator of poor prognosis. It can be seen in 1-3% of intraabdominal and pelvic malignancies. In the literature, around 300 studies are presented, mostly in the form of case reports. Very few (7-9%) of the cases with SMJN are from pancreatic origin. In our literature review, we found that in the majority (>90%) of SMJN cases due to pancreatic tumors, the lesions originated from the pancreatic tail and/or body, and tumor marker Ca-19.9 was very high in most cases (>90%). Aim. Here, the case of SMJN seen in a patient with three different primary tumors was discussed in the light of the literature data. Description of the case. Here, our case, whose third primary malignancy was detected in the pancreas in the PET/CT examination performed to investigate the origin of SMJN in a 68-year-old female patient who had undergone surgery due to breast in 2011 and endometrium cancers in 2018 and came with umbilical metastasis, is presented in the light of the literature data. Conclusion. As a result, in our case, which was followed up due to two primary tumors, it became important to know the origin of the SMJN that occurred due to the third primary tumor detected during the CT and PET/CT examination due to the newly emerging SMJN. It is important to know the origin and histopathological features of the SMJN in order to determine the treatment to the patient.
{"title":"Pancreatic tumor metastasis to the navel in a case with three primary tumors – case report and review of the literature","authors":"F. Dilek, Furkan Tosun, A. Atay, O. Dilek","doi":"10.15584/ejcem.2020.3.11","DOIUrl":"https://doi.org/10.15584/ejcem.2020.3.11","url":null,"abstract":"Introduction. Sister Mary Joseph nodule (SMJN) is a metastasis that can occur in the umbilical region due to many tumors in the abdomen. Most of the cases are of gastrointestinal system origin and are often an indicator of poor prognosis. It can be seen in 1-3% of intraabdominal and pelvic malignancies. In the literature, around 300 studies are presented, mostly in the form of case reports. Very few (7-9%) of the cases with SMJN are from pancreatic origin. In our literature review, we found that in the majority (>90%) of SMJN cases due to pancreatic tumors, the lesions originated from the pancreatic tail and/or body, and tumor marker Ca-19.9 was very high in most cases (>90%). Aim. Here, the case of SMJN seen in a patient with three different primary tumors was discussed in the light of the literature data. Description of the case. Here, our case, whose third primary malignancy was detected in the pancreas in the PET/CT examination performed to investigate the origin of SMJN in a 68-year-old female patient who had undergone surgery due to breast in 2011 and endometrium cancers in 2018 and came with umbilical metastasis, is presented in the light of the literature data. Conclusion. As a result, in our case, which was followed up due to two primary tumors, it became important to know the origin of the SMJN that occurred due to the third primary tumor detected during the CT and PET/CT examination due to the newly emerging SMJN. It is important to know the origin and histopathological features of the SMJN in order to determine the treatment to the patient.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82293612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Oyewole, Christiana Mautin Todowede, I. Dipeolu
Introduction. There is little information regarding childcare practices among adolescent mothers in the study areas. Aim. This study was aimed at investigating knowledge, perception and childcare practices among adolescent mothers. Material and methods. A descriptive cross-sectional survey was conducted on randomly select 382 adolescent mothers. A validated semi-structured questionnaire was used to collect data, which were analysed using, descriptive and multivariate analyses with p-value set at 0.05. Age of respondents was 18.5±0.7 years. Results. Majority (80.6%) had poor knowledge of when to start ante-natal care. Also, 70.0% of the respondents could not perceive growth monitoring as a necessary strategy for child survival and 86.4% perceived diarrhoea as normal for children during the teething period. Many (58.4%) did not practise exclusive breastfeeding. Respondents with secondary education were less likely to have poor knowledge than those with primary education (OR: 0.2, CI: 0.6-0.9, 95%). Respondents, who received supervision from older women during childcare, were less likely to have poor childcare practice than those who did not (OR: 0.2, CI: 0.4-0.7, 95%). Conclusion. Respondents had poor knowledge of childcare practices when childcare survival strategies were used as the yardstick for evaluation. Involvement of older women is suggested to assist adolescent mothers improve their knowledge and practices of childcare.
{"title":"Knowledge, perception and child care practices among adolescent mothers in Ibadan Metropolis, Nigeria","authors":"O. Oyewole, Christiana Mautin Todowede, I. Dipeolu","doi":"10.15584/ejcem.2020.3.4","DOIUrl":"https://doi.org/10.15584/ejcem.2020.3.4","url":null,"abstract":"Introduction. There is little information regarding childcare practices among adolescent mothers in the study areas. Aim. This study was aimed at investigating knowledge, perception and childcare practices among adolescent mothers. Material and methods. A descriptive cross-sectional survey was conducted on randomly select 382 adolescent mothers. A validated semi-structured questionnaire was used to collect data, which were analysed using, descriptive and multivariate analyses with p-value set at 0.05. Age of respondents was 18.5±0.7 years. Results. Majority (80.6%) had poor knowledge of when to start ante-natal care. Also, 70.0% of the respondents could not perceive growth monitoring as a necessary strategy for child survival and 86.4% perceived diarrhoea as normal for children during the teething period. Many (58.4%) did not practise exclusive breastfeeding. Respondents with secondary education were less likely to have poor knowledge than those with primary education (OR: 0.2, CI: 0.6-0.9, 95%). Respondents, who received supervision from older women during childcare, were less likely to have poor childcare practice than those who did not (OR: 0.2, CI: 0.4-0.7, 95%). Conclusion. Respondents had poor knowledge of childcare practices when childcare survival strategies were used as the yardstick for evaluation. Involvement of older women is suggested to assist adolescent mothers improve their knowledge and practices of childcare.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76061471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paulina Hejda, A. Hubert-Lutecka, Z. Chmiel, A. Sidor, G. Iwanowicz-Palus, Marcin Żal, Agnieszka Koryl, M. Binkowska-Bury
Introduction. Europe is the region with the greatest proportion of deaths (16%) attributable to tobacco smoking worldwide. Medical students and physicians should set an example of tobacco-smoking abstinence for their patients. Aim. The aim of the study was to compare opinions on behaviors and attitudes of Czech and Polish medical students about tobacco smoking and the position of a physician in anti-smoking counseling. Material and methods. The Global Health Professions Student Survey (GHPSS) was conducted among 707 medical students in Czech Republic in 2011 and among 1164 medical students in Poland. Results. Twety percent of polish and 25,7% of Czech medical students declared current tobacco smoking. Eighty-one percent in Poland and 60% in Czech Republic felt that physicians should be trained in smoking cessation techniques but only 27% of the medical students in Poland and 2,8% in Czech Republic , declared that such a course had been realized during the course
{"title":"Behaviors, attitudes and opinions of medical students in the field of smoking and anti-smoking counseling in two countries of Central and Eastern Europe","authors":"Paulina Hejda, A. Hubert-Lutecka, Z. Chmiel, A. Sidor, G. Iwanowicz-Palus, Marcin Żal, Agnieszka Koryl, M. Binkowska-Bury","doi":"10.15584/ejcem.2020.3.8","DOIUrl":"https://doi.org/10.15584/ejcem.2020.3.8","url":null,"abstract":"Introduction. Europe is the region with the greatest proportion of deaths (16%) attributable to tobacco smoking worldwide. Medical students and physicians should set an example of tobacco-smoking abstinence for their patients. Aim. The aim of the study was to compare opinions on behaviors and attitudes of Czech and Polish medical students about tobacco smoking and the position of a physician in anti-smoking counseling. Material and methods. The Global Health Professions Student Survey (GHPSS) was conducted among 707 medical students in Czech Republic in 2011 and among 1164 medical students in Poland. Results. Twety percent of polish and 25,7% of Czech medical students declared current tobacco smoking. Eighty-one percent in Poland and 60% in Czech Republic felt that physicians should be trained in smoking cessation techniques but only 27% of the medical students in Poland and 2,8% in Czech Republic , declared that such a course had been realized during the course","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73065686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Izabela Rodrigues Izabela Rodrigues Camilo, M. Wutzke, R. M. Costa, G. Bertolini, L. F. Ribeiro
To the Araucaria Foundation for funding with a scientifc initiation scholarship to IRC – 2018.
感谢Araucaria基金会为IRC - 2018提供科学启动奖学金。
{"title":"Morphology of extensor digitorum longus of Wistar rats after remobilization by vibratory platform","authors":"Izabela Rodrigues Izabela Rodrigues Camilo, M. Wutzke, R. M. Costa, G. Bertolini, L. F. Ribeiro","doi":"10.15584/ejcem.2019.4.2","DOIUrl":"https://doi.org/10.15584/ejcem.2019.4.2","url":null,"abstract":"To the Araucaria Foundation for funding with a scientifc initiation scholarship to IRC – 2018.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75848513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. Undergraduates in many institutions live a lifestyle that could predispose them to non-communicable diseases (NCDs) including cardiovascular-related. Previous studies on modifiable risk factors (MRFs) against NCDs had focused mainly on adults, whereas young people should be prime targets for prevention programmes. Aim. This study was aimed at investigating knowledge of MRFs against cardiovascular diseases (CVDs) among university undergraduates in Ibadan, Nigeria. Material and methods. A descriptive cross-sectional design was adopted, where 500 undergraduates participated. Data were collected using Focus Group Discussion (FGD) guide and validated questionnaire. Data analyses were conducted using thematic approach and bivariate methods at 5% levels of significance, respectively. Results. Mean age was 22.8 }3.0 years and 51.4% were females. The majority reported that their fathers (82.8%) and mothers (83.0%) had no hypertension history. The FGD revealed that students were knowledgeable of MRFs and preventive behaviours but still engaged in unhealthy lifestyle practices. The MRFs identified included excessive alcohol consumption (85.4%), unhealthy diet (77.6%), physical inactivity (75.2%) and smoking (70.2%). Respondents (56.4%) had good knowledge of MRFs against CVDs; 57.0% had fair lifestyle practices and 54.8% had good knowledge of preventive behaviour against CVDs. Conclusion. Gender was significantly associated with knowledge of CVDs preventive behaviours. Institutional-based lifestyle modification programmes, using peer group education is suggested.
{"title":"Knowledge of modifiable risk factors for cardiovascular diseases among university undergraduates in Ibadan, Nigeria","authors":"O. Oyewole, Ayodele Solabi","doi":"10.15584/ejcem.2020.3.7","DOIUrl":"https://doi.org/10.15584/ejcem.2020.3.7","url":null,"abstract":"Introduction. Undergraduates in many institutions live a lifestyle that could predispose them to non-communicable diseases (NCDs) including cardiovascular-related. Previous studies on modifiable risk factors (MRFs) against NCDs had focused mainly on adults, whereas young people should be prime targets for prevention programmes. Aim. This study was aimed at investigating knowledge of MRFs against cardiovascular diseases (CVDs) among university undergraduates in Ibadan, Nigeria. Material and methods. A descriptive cross-sectional design was adopted, where 500 undergraduates participated. Data were collected using Focus Group Discussion (FGD) guide and validated questionnaire. Data analyses were conducted using thematic approach and bivariate methods at 5% levels of significance, respectively. Results. Mean age was 22.8 }3.0 years and 51.4% were females. The majority reported that their fathers (82.8%) and mothers (83.0%) had no hypertension history. The FGD revealed that students were knowledgeable of MRFs and preventive behaviours but still engaged in unhealthy lifestyle practices. The MRFs identified included excessive alcohol consumption (85.4%), unhealthy diet (77.6%), physical inactivity (75.2%) and smoking (70.2%). Respondents (56.4%) had good knowledge of MRFs against CVDs; 57.0% had fair lifestyle practices and 54.8% had good knowledge of preventive behaviour against CVDs. Conclusion. Gender was significantly associated with knowledge of CVDs preventive behaviours. Institutional-based lifestyle modification programmes, using peer group education is suggested.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80348931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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