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Post SARS-CoV-2 infection and hair loss SARS-CoV-2感染后和脱发
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_16_21
Fahad K. Alrashidi, Nojoud Alaroush
People affected with severe acute respiratory syndrome coronavirus 2 can have a wide variety of symptoms. Literature and public discussion forums report persistent symptoms among COVID-19 survivors. More than 25% of COVID-19 survivors report hair loss as a persisting issue. The Centers for Disease Control and Prevention state that hair loss as a potential long-term effect of COVID-19 is currently under investigation. This report may be the first case of hair loss in the patient with postCOVID-19 infection in Saudi Arabia.
感染了严重急性呼吸综合征冠状病毒2的人可能会有各种各样的症状。文献和公共论坛报告了COVID-19幸存者的持续症状。超过25%的COVID-19幸存者报告脱发是一个持续存在的问题。美国疾病控制和预防中心表示,脱发作为COVID-19的潜在长期影响目前正在调查中。本报告可能是沙特阿拉伯首例covid -19感染后患者脱发病例。
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引用次数: 0
Vaccine induced mastocytoma 疫苗诱导的肥大细胞瘤
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_34_21
A. Alramthan, L. Ashour, Mohammed Alenezi
Mastocytoma has been reported to appear in close temporal or spatial relationship to intramuscular injection of Hepatitis B vaccine. Here, we report a case of isolated vaccine induced mastocytoma occurring in an 8-month-old female patient.
肥大细胞瘤的出现与肌肉注射乙型肝炎疫苗有密切的时间或空间关系。在这里,我们报告一例分离的疫苗诱导的肥大细胞瘤发生在一个8个月大的女性患者。
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引用次数: 0
Imiquimod cream improves photodamaged skin 咪喹莫特乳霜改善光损伤皮肤
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_39_19
Suliman Alfaraj, Y. Ghobara, A. Aleisa
Chronic exposure to ultraviolet light causes wrinkles and dyspigmentation. Imiquimod cream is an immune-modulator medication approved for the treatment of genital warts, actinic keratosis, and superficial basal cell carcinoma. Few scientific papers were published in the literature on the effect of imiquimod on photodamaged skin. We report four patients with benign and malignant cutaneous neoplasms who were treated with 5% imiquimod cream and noticed improvement in their skin appearance. We believe that imiquimod cream is a safe and effective option for improving photodamaged skin with excellent safety profile.
长期暴露在紫外线下会导致皱纹和色素沉着。咪喹莫特乳膏是一种免疫调节剂,被批准用于治疗生殖器疣、光化性角化病和浅表基底细胞癌。文献中关于咪喹莫特对光损伤皮肤的影响的科学论文很少。我们报告了4例良性和恶性皮肤肿瘤患者,他们用5%咪喹莫特乳膏治疗,并注意到他们的皮肤外观改善。我们相信咪喹莫特乳霜是一种安全有效的选择,改善光损伤皮肤,具有良好的安全性。
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引用次数: 0
Glomus tumor presenting as atypical tender papule on the lower limb 下肢血管球瘤表现为不典型的压痛丘疹
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_58_19
Banupriya Mani, A. Priyadarshini, G. Rajesh, A. Sankarasubramanian
Glomus tumor is a benign vascular tumor derived from modified smooth muscle cells of the glomus body. Although they can develop in any part of the body, they commonly do so in the upper extremities, most frequently in the subungual region of fingers. They can be either solitary or multiple. Extradigital glomus tumors are often misdiagnosed owing to their nonspecific clinical presentations and unusual locations. We report two cases of extradigital glomus tumor occurring at unusual sites such as knee and thigh.
血管球瘤是一种源自血管球小体改良的平滑肌细胞的良性血管肿瘤。虽然它们可以发生在身体的任何部位,但它们通常发生在上肢,最常发生在手指的趾下区域。它们可以是单独的,也可以是多个。指外血管球瘤由于其非特异性的临床表现和不寻常的位置而经常被误诊。我们报告两例指外血管球瘤发生在不寻常的部位,如膝盖和大腿。
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引用次数: 0
A case of topical rapamycin effective for postsurgical hypertrophic scar of superficial lymphatic malformation with possible quality-of-life improvement 局部雷帕霉素治疗浅表淋巴畸形术后增生性瘢痕的疗效,可能改善患者的生活质量
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_38_21
Yukinori Isozaki, Motoi Kato, N. Fujita, Shota Tojo, M. Fujiki, Azusa Watanabe, Shoji Watanabe
Lymphatic malformation (LM) of the body surface causes symptoms such as bleeding, pain, lymphatic leakage, or infection of the lesion, usually treated with surgical resection and sclerotherapy, with limited efficacy. The vesicles of the body surface tend to recur after surgical resection and may cause lymphatic leakage, which could be long term a burden for patients, eventually decreasing their quality of life. In recent years, the efficacy of orally administered mammalian target of rapamycin inhibitor (rapamycin) has been reported for LM and other vascular anomalies but few are reported in the East Asian population. We report the case of a Japanese female with intractable gluteal LM that was successfully treated with topical rapamycin for postoperative recurrence and hypertrophic scarring.
体表淋巴畸形(LM)引起病变出血、疼痛、淋巴渗漏或感染等症状,通常采用手术切除和硬化疗法治疗,但疗效有限。体表囊泡易在手术切除后复发,并可能引起淋巴渗漏,长期给患者带来负担,最终降低患者的生活质量。近年来,口服哺乳动物雷帕霉素靶点抑制剂(雷帕霉素)对LM和其他血管异常的疗效已有报道,但在东亚人群中很少报道。我们报告的情况下,日本女性顽固性臀LM成功地用局部雷帕霉素治疗术后复发和增生性瘢痕。
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引用次数: 0
Tinea incognita with secondary bacterial infection 隐蔽性足癣伴继发细菌感染
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_22_19
Daniel A Nadelman
Tinea incognita is a phenomenon occurring when a fungal infection is erroneously treated with topical corticosteroids. This worsens the underlying infection without becoming clinically apparent until treatment is withdrawn, in which case the tinea infection becomes acutely symptomatic. We herein report a case of tinea incognita in a young woman treated with high-potency topical corticosteroids, leading to worsening dermatophyte infection and coinfection with Klebsiella oxytoca. The resulting infection required aggressive oral and topical antimicrobial treatment before resolving. This case illustrates the potentially harmful sequelae of using high-potency topical corticosteroids without first ruling out tinea infection.
不明足癣是一种现象发生时,真菌感染是错误的治疗与局部皮质类固醇。这加重了潜在的感染,没有成为临床明显,直到治疗撤回,在这种情况下,足癣感染成为急性症状。我们在此报告一个病例的不明癣在一个年轻的妇女治疗高效外用皮质类固醇,导致恶化的皮肤真菌感染和合并感染克雷伯氏菌。由此产生的感染需要积极的口服和局部抗菌治疗才能解决。本病例说明了在不首先排除足癣感染的情况下使用高效外用皮质类固醇的潜在有害后果。
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引用次数: 1
Spotted fever rickettsioses should be considered in the differential diagnosis of “Fever with Purpuric Rash” in Saudi Arabia: A Case report 斑点热立克次体病应考虑在鉴别诊断“发烧与紫疹”在沙特阿拉伯:一个病例报告
Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_99_20
A. Nassar, A. Abu-aliat, S. Jamil, Mohammed S Alshahrani, S. Hawwam, Esmat Eid
There is a paucity of literature about human spotted fever rickettsioses (SFR) from the Arab Gulf Region, including Saudi Arabia. Here, we present an elderly Saudi man who had fever, headache, purpuric maculopapular skin rash, and an eschar. Together, the clinical findings, the serologic positivity, the presence of a vector tick in addition to the histopathologic changes, and the dramatic clinical response to oral doxycycline confirmed the diagnosis of SFR. This may be the first case of SFR reported to the health-care authorities in Saudi Arabia. We recommend considering SFR in the differential diagnosis of “fever with purpuric rash” in Saudi Arabia. Ideally, treatment with a tetracycline antibiotic should be considered for patients with fever and headache even before a purpuric rash develops.
关于阿拉伯海湾地区(包括沙特阿拉伯)人类斑点热立克次体病(SFR)的文献很少。在这里,我们提出一个老年沙特男子谁发烧,头痛,紫癜斑丘疹皮肤皮疹,和一个痂。临床表现、血清学阳性、媒介蜱虫的存在以及组织病理学改变以及口服强力霉素的显著临床反应共同证实了SFR的诊断。这可能是向沙特阿拉伯卫生保健当局报告的首例SFR病例。我们建议在沙特阿拉伯的“发热伴紫癜皮疹”的鉴别诊断中考虑SFR。理想情况下,在出现紫癜性皮疹之前,应该考虑使用四环素类抗生素治疗发烧和头痛的患者。
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引用次数: 0
Serum Vitamin B12 in chronic telogen effluvium patients: A case–control study 慢性休止期排尿患者血清维生素B12:一项病例对照研究
Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_64_22
P. Mamatha, K. Aparna
Background: Diffuse hair loss is a common complaint in dermatology clinics. Chronic telogen effluvium is a common form of diffuse hair loss. Chronic telogen effluvium is characterized usually by the abrupt onset of diffuse shedding of telogen hairs for more than 6 months. Micronutrients such as Vitamin B 12 are major elements in the normal hair follicle cycle. Vitamin B12 levels in chronic telogen effluvium are not well characterized. Purpose: The aim of this study is to compare Vitamin B12 levels in chronic telogen effluvium patients to controls. Methods: A case–control study was conducted in the department of dermatology of a tertiary care hospital; a total of 70 patients were included, 35 in each group. Results: Twenty-five(71%) chronic telogen effluvium patients were females; 60% had Vitamin B12 deficiency (<250 pg/ml). In controls, fewer (26%) subjects had Vitamin B12 deficiency (P = 0.004). Conclusion: As per our study, Vitamin B12 deficiency was more common in patients with telogen effluvium than in controls.
背景:弥漫性脱发是皮肤科临床常见的主诉。慢性休止期脱发是弥漫性脱发的一种常见形式。慢性休止期脱发的特征通常是突然开始的弥漫性脱落的休止期毛发超过6个月。像维生素b12这样的微量元素是正常毛囊周期的主要元素。慢性休止期排出物中的维生素B12水平尚未得到很好的表征。目的:本研究的目的是比较慢性休止期排尿患者与对照组的维生素B12水平。方法:在某三级医院皮肤科进行病例对照研究;共纳入70例患者,每组35例。结果:慢性休止期排尿患者中女性25例(71%);60%的人缺乏维生素B12 (<250 pg/ml)。在对照组中,较少(26%)的受试者缺乏维生素B12 (P = 0.004)。结论:根据我们的研究,维生素B12缺乏症在休止期排尿患者中比在对照组中更常见。
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引用次数: 0
Delayed-onset urticaria following vaccination for COVID-19 COVID-19疫苗接种后的延迟性荨麻疹
Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_67_22
Brandon Clark, B. Yentzer
Background: As COVID-19 vaccines continue to be administered worldwide, there are an increasing number of studies documenting cutaneous reactions following vaccination. Systemic reactions, such as urticarial diseases, occur. Purpose: The main objective of this study was to investigate the association between urticaria and recent vaccination for COVID-19. Methods: A retrospective chart review examining the association of urticaria and COVID vaccination was conducted. Results: We report 17 patients who developed an urticarial reaction following vaccination against COVID and one patient who developed an urticarial reaction following a COVID infection. The vast majority of the patients were women with a mean age of 42.8 years. Conclusion: Cutaneous manifestations often follow COVID vaccination and infection. It may be helpful to inquire about recent infections and vaccinations in patients presenting with urticarial diseases.
背景:随着COVID-19疫苗在世界范围内继续接种,越来越多的研究记录了疫苗接种后的皮肤反应。会发生全身反应,如荨麻疹疾病。目的:本研究的主要目的是调查荨麻疹与最近接种COVID-19疫苗之间的关系。方法:回顾性分析荨麻疹与COVID - 19疫苗接种的关系。结果:我们报告了17例在接种COVID疫苗后发生荨麻疹反应的患者和1例在COVID感染后发生荨麻疹反应的患者。绝大多数患者为女性,平均年龄为42.8岁。结论:新冠肺炎疫苗接种和感染后常出现皮肤症状。询问有荨麻疹疾病的患者最近的感染和疫苗接种情况可能会有所帮助。
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引用次数: 1
Vaccine-induced pityriasis rosea and pityriasis rosea-like Eruptions: A review of literature and a case report of COVID-19 vaccine-induced pityriasis rosea 疫苗致玫瑰糠疹和玫瑰糠疹样疹:新冠病毒疫苗致玫瑰糠疹的文献回顾及1例报告
Pub Date : 2022-07-01 DOI: 10.4103/jdds.jdds_7_22
Eman Almukhadeb, Faisal Alghubaywi, Y. Alharthi, Amer Alharbi
Pityriasis rosea (PR) is frequently proposed to result from a viral etiology. In line with the current pandemic, COVID-19 vaccines are noticed to trigger PR development. Our patient is a 23-year-old female who developed an itchy skin rash following the Pfizer–BioNTech COVID-19 vaccine. Examination showed one erythematous plaque on the left shoulder and multiple small scaly plaques of similar appearance distributed over the trunk and proximal extremities. The patient was clinically diagnosed, educated, reassured, prescribed topical mometasone ointment and oral chlorpheniramine, and was given a follow-up appointment. We report this case to increase awareness on COVID-19 vaccines as potential triggers of PR.
玫瑰性糠疹(PR)通常被认为是由病毒引起的。根据目前的大流行,人们注意到COVID-19疫苗会引发公关开发。我们的患者是一名23岁的女性,她在接种了辉瑞- biontech COVID-19疫苗后出现了瘙痒的皮疹。检查显示左肩有一个红斑斑块,躯干和四肢近端分布有多个类似外观的小鳞状斑块。对患者进行临床诊断、教育、安抚,给予局部莫米松软膏和口服氯苯那敏,并随访预约。我们报告这一病例是为了提高人们对COVID-19疫苗作为PR潜在触发因素的认识。
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引用次数: 0
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Journal of Dermatology and Dermatologic Surgery
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