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How internet search and patient's self-diagnosis helped in the management of a case of paederus dermatitis 网络搜索和患者自我诊断如何帮助处理一例无足性皮炎
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_40_19
Shaikat Mondal, Himel Mondal
Searching symptoms on the internet and self-diagnosis is being criticized for its uncertainty in the diagnosis. However, it may help the patient and the doctor in the diagnosis and management of a disease. In this article, we present a case where the use of smartphone and internet search helped the patient and the doctor in the initial management and diagnosis of paederus dermatitis. A 34-year-old male, an urban inhabitant, noticed pain on the right side of his neck while he was sleeping at night. He woke up and noticed a beetle on his pillow. As the beetle was an unfamiliar one, he took pictures on his smartphone and searched about the beetle on the internet. From the results, he identified the beetle as “Nairobi fly,” self-diagnosed it as “paederus dermatitis,” and washed the area with soap and water to remove vesicant secreted by the beetle. Next day morning, he presented with severe pain and mild erythema on the right side of the neck. The diagnosis becomes obvious from the images shown by the patient. The patient was treated with a topical steroid and oral antihistaminic for 7 days. The patient recovered from dermatitis on the 10th day.
在网上搜索症状和自我诊断的方法因诊断的不确定性而受到批评。然而,它可以帮助病人和医生在疾病的诊断和管理。在这篇文章中,我们提出了一个案例,其中使用智能手机和互联网搜索帮助患者和医生在最初的管理和诊断的padeus皮炎。一名34岁的男性,城市居民,晚上睡觉时发现右颈部疼痛。他醒了,发现枕头上有一只甲虫。由于这只甲虫很陌生,他就用智能手机拍了照片,然后上网搜索。根据检测结果,他将这只甲虫鉴定为“内罗毕蝇”,并将其自我诊断为“翅虫性皮炎”,并用肥皂和水清洗这片区域,以去除甲虫分泌的除臭剂。第二天早晨,患者出现颈部右侧剧烈疼痛和轻度红斑。从病人所显示的图像来看,诊断是显而易见的。患者给予局部类固醇和口服抗组胺药治疗7天。患者于第10天皮炎痊愈。
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引用次数: 0
Successful use of dupilumab for treatment-resistant pityriasis amiantacea 杜匹单抗成功用于治疗难治性肛周癣
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_109_20
Maya Firsowicz, T. Willenbrink, Nova Shu, J. Reichenberg
Pityriasis amiantacea (PA) is a scalp condition characterized by thick, adherent scales that are silvery or yellow–gray in color and bind down tufts of hair. PA is associated with several underlying dermatologic conditions including psoriasis, seborrheic dermatitis, atopic dermatitis, tinea capitis, pityriasis rosea, and Darier's disease. Although there is no consensus on standard treatment, PA is generally treated with keratolytic agents and/or ketoconazole shampoo. More resistant cases may require systemic therapies, including tumor necrosis factor-alpha inhibitors. We report a case of a 57-year-old female with severe PA resistant to numerous treatments including topical steroids, salicylic acid shampoo, intralesional steroid injections, mycophenolate mofetil, adalimumab, and apremilast. Following treatment with dupilumab, our patient experienced complete resolution of her PA. These results suggest that dupilumab may have in a role in the management of treatment-resistant PA, particularly when associated with eczematous dermatitis.
amanantacea (PA)是一种头皮疾病,其特征是厚厚的,粘附的鳞片是银色或黄灰色的,并束缚了一簇簇的头发。PA与几种潜在的皮肤病有关,包括牛皮癣、脂溢性皮炎、特应性皮炎、头癣、玫瑰糠疹和达里尔病。虽然标准治疗方法尚无共识,但PA通常使用角膜溶解剂和/或酮康唑洗发水治疗。更耐药的病例可能需要全身治疗,包括肿瘤坏死因子- α抑制剂。我们报告一例57岁女性严重PA耐多种治疗,包括外用类固醇、水杨酸洗发水、病灶内类固醇注射、霉酚酸酯、阿达木单抗和阿普雷米司特。在使用dupilumab治疗后,我们的患者经历了PA的完全消退。这些结果表明,dupilumab可能在治疗抵抗性PA中发挥作用,特别是当与湿疹性皮炎相关时。
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引用次数: 1
Eccrine porocarcinoma at unusual location 异常部位的内分泌腺癌
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_40_21
S. Tomar, B. Supekar, Ravi Bhushan, J. Mukhi, R. Singh, D. Bhat, Abhisek Jaiswal
Porocarcinoma is a malignant tumor arising from intraepidermal eccrine duct epithelium or acrosyringium with an aggressive course. Sites of predilection include lower extremities (50%), trunk (24%), and head and neck (24%), while it is uncommon in the upper extremities and genitals. We report a case of eccrine porocarcinoma in the axillary region with axillary lymph node involvement and pulmonary metastasis in a 78-year-old male.
多孔癌是一种发生于表皮内分泌管上皮或顶管的恶性肿瘤,病程具有侵袭性。偏爱的部位包括下肢(50%)、躯干(24%)和头颈部(24%),而上肢和生殖器少见。我们报告一例78岁男性腋窝淋巴结累及及肺转移的腋窝汗腺癌病例。
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引用次数: 0
A rare case of lethal midline granuloma posing a diagnostic challenge in COVID times and the response to chemotherapy 罕见的致命中线肉芽肿在COVID时期提出诊断挑战和对化疗的反应
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_56_21
Ajeet Singh, R. Arora, Satyaki Ganguly, R. Satarkar
Lethal midline granuloma is a rare aggressive, mutilating disorder of the upper airways. It is most likely secondary to natural killer/T-cell lymphoma and is difficult to diagnose owing to the varied and nonspecific symptoms. It is usually prevalent in the fourth decade of life and carries a poor prognosis. Our patient was a 19-year-old male with disease duration of 3 months, was diagnosed with lethal midline granuloma based on clinical examination, histopathology, and immunohistochemistry. The patient responded well to the first cycle of chemotherapy.
致死性中线肉芽肿是一种罕见的上呼吸道侵袭性致残性疾病。它很可能继发于自然杀伤/ t细胞淋巴瘤,由于症状多样和非特异性,难以诊断。它通常常见于生命的第四个十年,预后较差。患者男,19岁,病程3个月,经临床检查、组织病理及免疫组化诊断为致死性中线肉芽肿。病人对第一轮化疗反应良好。
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引用次数: 0
Madarosis in a normolipidemic woman: Is giant xanthelasma palpebrarum the culprit? 正常血脂女性骨质疏松症:巨大的睑黄斑是罪魁祸首吗?
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_108_20
S. Desai, H. Pathave, Abigail Syiemlieh, C. Nayak
Xanthelasma palpebrarum (XP) is the most common cutaneous xanthoma. It is triggered by hyperlipidemia, thyroid dysfunction, and diabetes mellitus. Madarosis, loss of eyebrows, occurs in various diseases ranging from local dermatological disorders to complex systemic diseases. Herein, we present a case of giant XP in a middle-aged female in whom bilateral partial madarosis developed. In polarized contact dermoscopy, the number of hairs on xanthoma plaque was reduced compared to normal.
黄斑瘤(XP)是最常见的皮肤黄瘤。它是由高脂血症、甲状腺功能障碍和糖尿病引发的。眉肥大症,即眉毛的丧失,发生在各种疾病中,从局部皮肤病到复杂的全身性疾病。在此,我们提出一例巨大的XP在一个中年女性在双侧部分骨质疏松症发展。在偏振接触皮肤镜下,黄斑斑块上的毛发数量比正常人减少。
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引用次数: 0
Lichenoid drug eruption induced by chlordiazepoxide 氯二氮环氧化物致地衣类药疹
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_35_20
Osamah Alkhuzaim
Lichenoid drug reaction is a cutaneous drug eruption due to a Type IV delayed hypersensitivity reaction. It usually occurs months to years following the intake of the drug and is characterized by purple, flat, polygonal papules that spread symmetrically and diffusely across the body. We report the case of a 26-year-old female, who was on chlordiazepoxide for the treatment of insomnia, and presented with multiple, annular, purple, scaly, itchy plaques over her breasts. The eruption progressed to involve the thighs and buccal mucosa and did not respond to topical antifungals. Skin biopsy revealed lichenoid lymphocytic infiltrate consistent with lichen planus. After discontinuation of chlordiazepoxide, her skin eruption significantly improved within 3 months. To our knowledge, this is the first case report of a patient who developed a lichenoid drug reaction to chlordiazepoxide.
地衣类药物反应是由IV型迟发性超敏反应引起的皮肤药疹。它通常发生在服用该药后的几个月到几年,其特征是紫色、扁平、多边形丘疹,对称地扩散到全身。我们报告一例26岁的女性,谁是氯二氮环氧化物治疗失眠,并提出了多个,环形,紫色,鳞状,发痒斑块在她的乳房。皮疹进展到累及大腿和颊黏膜,局部抗真菌药无效。皮肤活检显示扁平苔藓样淋巴细胞浸润。停药后3个月内皮肤出疹明显改善。据我们所知,这是首例对氯二氮环氧化物产生地衣类药物反应的病例报告。
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引用次数: 1
Bullous pemphigoid: Associating with the multifaceted phenomenon of koebner 大疱性类天疱疮:与多方面的koebner现象有关
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_142_20
S. Nayak, Shukriti Shenoi, S. Prabhu, R. Rao
Koebner phenomenon (KP) or isomorphic phenomenon often helps in diagnosis of certain conditions and often reflects disease activity. Although commonly reported with psoriasis, vitiligo, and lichen planus, KP has been occasional reported with other conditions. Bullous pemphigoid has a rare association with this and we report a case with scratching being the inciting factor. A 50-year-old female with no comorbidities presented with itchy fluid-filled lesions all over the body for 15 days. Examination showed generalized distribution of bullae and vesicles with linear bulla on the forearms. Histopathology and immunofluorescence studies were conclusive of bullous pemphigoid. KP has been reported in general due to mechanical trauma, therapy, dermatoses, or reactions. KP in bullous pemphigoid is rarely reported and it is mentioned in the category IV of Boyd and Nelder classification. The linear nature of bulla in our patient was suggestive of scratching being the inciting factor for KP, which has not been reported to the best of our knowledge.
Koebner现象(KP)或同构现象通常有助于某些疾病的诊断,并经常反映疾病的活动性。虽然常报道与牛皮癣,白癜风,和扁平苔藓,KP已偶尔报道与其他条件。大疱性类天疱疮与此有罕见的关联,我们报告一个病例与抓挠是刺激因素。一名50岁女性,无合并症,表现为全身发痒充满液体的病变,持续15天。检查显示前臂大泡和小泡广泛分布,有线状大泡。组织病理学和免疫荧光研究证实为大疱性类天疱疮。KP一般由机械性创伤、治疗、皮肤病或反应引起。大疱性类天疱疮的KP很少被报道,在Boyd和Nelder分类的第IV类中被提及。本例患者大疱的线性特征提示划伤是KP的诱发因素,据我们所知尚未有相关报道。
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引用次数: 0
Generalized exanthem as a presenting symptom of COVID-19 广泛性惊厥是COVID-19的主要症状
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_138_20
Lama Altawil, Nojoud Alajroush
Coronavirus disease 2019 (COVID-19) has many cutaneous manifestations. We describe a 30-year-old otherwise healthy male with a generalized purpuric exanthem. Ten days after the onset of the rash, he presented with fatigue, dry cough, shortness of breath, anosmia, and ageusia and was diagnosed as having COVID-19. The presence of an extensive exanthem in an otherwise healthy patient could raise suspicion for underlying COVID-19.
冠状病毒病2019 (COVID-19)有许多皮肤表现。我们描述一个30岁的健康男性与广泛性紫癜exanthem。皮疹发作10天后,患者出现疲劳、干咳、呼吸急促、嗅觉丧失和衰老,并被诊断为COVID-19。在其他方面健康的患者中出现广泛的检查可能会引起对潜在COVID-19的怀疑。
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引用次数: 0
Nonfamilial isolated collagenoma 非家族性孤立性胶原瘤
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_2_20
F. Taj, Dilsha Shareef
Connective tissue nevi (CTN) are hamartomas consisting of the various components of the dermal connective tissue. The predominant element of the extracellular connective tissue within an individual nevus can be collagen, elastic fibers, or glycosaminoglycans. Those predominantly composed of collagen are called collagenomas. CTN can be classified as congenital or acquired, and independent or in association with a systemic disease. Collagenomas are asymptomatic and can be seen over the trunk, arm, thigh, and soles. We present the case of an 18-year-old boy with an isolated collagenoma over the lower back.
结缔组织痣(CTN)是由真皮结缔组织的各种成分组成的错构瘤。单个痣内细胞外结缔组织的主要成分可以是胶原蛋白、弹性纤维或糖胺聚糖。那些主要由胶原蛋白组成的被称为胶原瘤。CTN可分为先天性或获得性,独立或与全身性疾病相关。胶原瘤无症状,可见于躯干、手臂、大腿和脚底。我们提出的情况下,一个18岁的男孩与孤立的胶原瘤在下背部。
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引用次数: 0
Peripheral neuropathy associated with tofacitinib use in alopecia universalis 托法替尼治疗秃发的周围神经病变
Pub Date : 2022-08-01 DOI: 10.4103/jdds.jdds_69_19
Raghad Alharthi, Fatimah S. Alowirdi, Saba Alsuhaymi, Mohammed Alqahtani, Afaf Alsheikh
Alopecia areata (AA) is an autoimmune disease characterized by nonscarring hair loss. Alopecia universalis (AU) is the advanced form of AA characterized by complete scalp and body hair loss. Traditional medical therapies for AA include topical and intralesional corticosteroids, topical anthralin immunotherapy, and light therapy. Tofacitinib is a Janus kinase-1 and 3 inhibitor used in the treatment of AA. In this report, we describe a 20-year-old female with AU refractory to topical therapies; thus, she was started on tofacitinib. Mild peripheral neuropathy was an unanticipated side effect that could be kept into consideration.
斑秃(AA)是一种以无瘢痕性脱发为特征的自身免疫性疾病。普遍秃(AU)是AA的高级形式,其特征是头皮和身体完全脱发。AA的传统医学治疗包括局部和局灶内皮质类固醇、局部炭疽免疫治疗和光疗。托法替尼是一种用于治疗AA的Janus激酶-1和3抑制剂。在这篇报道中,我们描述了一位20岁的女性AU对局部治疗难治性;因此,她开始使用托法替尼。轻度周围神经病变是一种未预料到的副作用,可以考虑。
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引用次数: 1
期刊
Journal of Dermatology and Dermatologic Surgery
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