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A comparison of autologous serum, plasma, and whole blood for intradermal autoreactivity testing in patients with chronic spontaneous urticarial: A cross-sectional study 慢性自发性荨麻疹患者皮内自体反应性检测的自体血清、血浆和全血比较:一项横断面研究
Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_72_21
Rasimah Ismail, A. Jamil, N. Md Nor, M. Bakhtiar
Background: Autologous serum (ASST) and plasma (APST) skin testing confirm autoreactivity in chronic spontaneous urticaria (CSU). Whole blood autohemotherapy has been used. Plasma and even whole blood may be used instead of serum with relatively quicker preparation and cheaper method especially using the latter in centers with limited resources. Purpose: The purpose of the study is to determine if similar intradermal skin reactions can be observed when using either serum, plasma, or whole blood in autologous skin tests and to determine factors associated with positive tests and wheal diameter. Methods: We performed a cross-sectional study of chronic urticaria patients in a dermatology clinic. Tests were performed according to EAACI/GA2 LEN Task Force recommendations. Urticaria Activity Score over 7 days (UAS7) was assessed. Statistical analyses included Chi-square, Mann–Whitney U, Spearman's, and Wilcoxon rank tests. Results: Twenty-six (77%) females and 8 (24%) males mean age 34 (26–42) years participated. ASST, APST and autologous whole blood for skin testing (AWBST) positivity rates were 24%, 29% and 27%, respectively (P = 0.86). 13 (38%) had at least 1 positive test; all tests were negative in 21 (62%). All tests were positive in 7 (21%), 3 (23%) were positive APST alone, 2 (15%) AWBST, 1 (8%) ASST. Pretest UAS7 was higher with those with test positive (P = 0.04). Test results were unaffected by age, gender, disease duration, atopy, anti-nuclear antibody, and thyroid status. Wheal diameter correlated with thyroid-stimulating hormone (P = 0.04). Conclusion: Autoreactivity rates were similar with ASST, APST, and AWBST. Positive tests were associated with severe CSU. Autologous whole blood may be a simpler and less costly alternative to plasma and serum for autoreactivity skin testing in patients with chronic urticaria.
背景:自体血清和血浆皮肤试验证实慢性自发性荨麻疹(CSU)的自身反应性。已采用全血自体血液疗法。血浆甚至全血可以代替血清,制备速度较快,方法便宜,特别是在资源有限的中心使用血清。目的:本研究的目的是确定在自体皮肤试验中使用血清、血浆或全血时是否可以观察到类似的皮内皮肤反应,并确定与阳性试验和轮径相关的因素。方法:我们对皮肤科门诊的慢性荨麻疹患者进行了横断面研究。根据EAACI/GA2 LEN工作组的建议进行了测试。评估7天以上荨麻疹活动评分(UAS7)。统计分析包括卡方检验、Mann-Whitney U检验、Spearman’s检验和Wilcoxon秩检验。结果:女性26例(77%),男性8例(24%),平均年龄34岁(26-42岁)。自体全血皮肤试验(AWBST)阳性率分别为24%、29%和27% (P = 0.86)。至少1次阳性检查13例(38%);21例(62%)检测结果均为阴性。所有试验均阳性7例(21%),单APST阳性3例(23%),AWBST阳性2例(15%),asst阳性1例(8%)。试验前UAS7高于试验阳性(P = 0.04)。测试结果不受年龄、性别、病程、特应性、抗核抗体和甲状腺状态的影响。轮径与促甲状腺激素相关(P = 0.04)。结论:自体反应率与自体血清、APST、AWBST相似。阳性结果与严重的CSU相关。自体全血可能是慢性荨麻疹患者自体反应性皮肤试验中较血浆和血清更简单、成本更低的替代方法。
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引用次数: 0
Assessment of the Saudi Arabian telemedicine experience during the COVID-19 pandemic: Dermatology-related consultations as a case 评估沙特阿拉伯在2019冠状病毒病大流行期间的远程医疗经验:以皮肤病学相关咨询为例
Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_67_21
S. Alsharif, N. Alsharif, Rimaz Alassiri, Ghaidaa Khouj, Nourah Alshareef, A. Aloufi, A. Hussain
Background: COVID-19 is a pandemic disease that spreads rapidly. The World Health Organization recommended social distancing to prevent disease transmission. Telemedicine was one of the most important tools used during the pandemic to provide health-care services. Different clinics, including dermatology clinics, tended to use telehealth and online tools. In addition, various dermatological conditions were diagnosed and treated by family physicians using the telemedicine applications of the Saudi Ministry of Health (MOH). Purpose: The present study aimed to evaluate the efficacy of family physicians using telemedicine to diagnose and manage different dermatological conditions. Specifically, we aimed to identify the common dermatological conditions that family physicians faced during the COVID-19 pandemic, as well as the use of the various telemedicine applications launched by the Saudi MOH. We also intended to assess the need for dermatologists in the telemedicine applications of the Saudi MOH and suggest possible improvements to the telemedicine process and related Saudi MOH applications for sustainable online health care. Methods: The cross-sectional study was conducted across Saudi Arabia among family physicians and general practitioners to assess their perception of using telemedicine for dermatology-related consultations. The self-administered survey questionnaire contained 16 questions in five sections. Results: A total of 302 family medicine and general physicians completed the questionnaire. Altogether, 165 (54.6%) physicians reported that they had never used telemedicine before the COVID-19 pandemic, while 12.9% reported frequent to continuous use. During the pandemic, 86.8% of family and general physicians used telemedicine for dermatological consultations. The most used methods were phone calls (57.6%) and the SEHA application (42.7%). A total of 96.4% of participants reported that they dealt with dermatological conditions before the COVID-19 pandemic. Interestingly, about 99% of family physicians reported that they faced difficulty diagnosing dermatology-related consultations. Telemedicine was frequently used by all physicians in the central region compared with 76.7% of those in the western region (P = 0.035). Conclusion: Family physicians in Saudi Arabia increased their telemedicine practicing during the pandemic. Different telemedicine tools were used, such as phone calls, virtual clinics, and Saudi MOH applications (SEHA, TETAMMAN, TABAUD, TAWAKKALNA). The majority of family physicians faced difficulty diagnosing dermatological conditions. In addition, most reported that dermatologists should be part of health-care facilities and telemedicine centers to deal with dermatology-related consultations.
背景:COVID-19是一种快速传播的大流行疾病。世界卫生组织建议保持社会距离以防止疾病传播。远程医疗是大流行期间提供保健服务的最重要工具之一。不同的诊所,包括皮肤科诊所,倾向于使用远程保健和在线工具。此外,家庭医生利用沙特卫生部(MOH)的远程医疗应用程序诊断和治疗各种皮肤病。目的:本研究旨在评估家庭医生使用远程医疗诊断和管理不同皮肤病的效果。具体而言,我们旨在确定家庭医生在2019冠状病毒病大流行期间面临的常见皮肤病,以及沙特卫生部推出的各种远程医疗应用程序的使用情况。我们还打算评估沙特卫生部远程医疗应用中对皮肤科医生的需求,并建议对远程医疗流程和相关的沙特卫生部可持续在线医疗应用进行可能的改进。方法:横断面研究在沙特阿拉伯的家庭医生和全科医生中进行,以评估他们对使用远程医疗进行皮肤病学相关咨询的看法。自我调查问卷分为5个部分,共16个问题。结果:共有302名家庭医生和全科医生完成问卷调查。总共有165名(54.6%)医生报告说,他们在COVID-19大流行之前从未使用过远程医疗,而12.9%的医生报告经常或持续使用远程医疗。大流行期间,86.8%的家庭医生和全科医生使用远程医疗进行皮肤病会诊。使用最多的方法是电话(57.6%)和SEHA申请(42.7%)。共有96.4%的参与者报告说,他们在COVID-19大流行之前处理过皮肤病。有趣的是,大约99%的家庭医生报告说,他们在诊断皮肤科相关咨询时遇到了困难。中部地区医师均使用远程医疗,西部地区使用率为76.7% (P = 0.035)。结论:沙特阿拉伯家庭医生在疫情期间增加了远程医疗实践。使用了不同的远程医疗工具,如电话、虚拟诊所和沙特卫生部应用程序(SEHA、TETAMMAN、TABAUD、TAWAKKALNA)。大多数家庭医生在诊断皮肤病方面面临困难。此外,大多数人报告说,皮肤科医生应该成为保健设施和远程医疗中心的一部分,以处理与皮肤科有关的咨询。
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引用次数: 0
Lichen planus after COVID-19 vaccination: A report of two cases 新冠肺炎疫苗接种后扁平苔藓2例报告
Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_15_22
S. Alotaibi, Ruaa Alharithy, Faisal A Alsharif, Norah Alkhayal
Lichen planus is a T-cell-mediated inflammatory disease that can be associated with preexposure to particular agents encompassing vaccines, viruses, and drugs. The origin of the disease is unknown and has varying clinical presentations, the recent manufactured COVID-19 vaccines have been linked with several cutaneous reactions that are similar to the cutaneous manifestations of COVID-19 virus infection, the majority of people developed cutaneous manifestations after the second dose of Pfizer vaccine, recent cases have been reported as a flare of a preexisting lichen planus following the administering of the Pfizer vaccine. We present a two interesting cases that developed a dermatological condition post Pfizer-BioNTech's COVID-19 vaccine. The first case is a 60-year-old man, with a past medical history of having lichen planus 15 years ago, that have been treated and controlled successfully with topical therapy, flared up following the administration of Pfizer-BioNTech's COVID-19 vaccine. The second case is a 57-year-old female with a past medical history of hypertension and hypothyroidism controlled. Develop the new onset of lichen planus after receiving the third dose of the COVID 19 vaccine. The lesions arise 3 weeks after the third dose.
扁平苔藓是一种t细胞介导的炎症性疾病,可能与预先暴露于包括疫苗、病毒和药物在内的特定介质有关。该疾病的起源尚不清楚,具有不同的临床表现,最近生产的COVID-19疫苗与几种皮肤反应有关,这些反应与COVID-19病毒感染的皮肤表现相似,大多数人在注射第二剂辉瑞疫苗后出现皮肤表现,最近有报告称,在注射辉瑞疫苗后,先前存在的扁平地衣突然出现。我们介绍了两个有趣的病例,他们在辉瑞生物技术公司(Pfizer-BioNTech)的COVID-19疫苗后出现了皮肤病。第一个病例是一名60岁的男性,15年前有扁平苔藓的病史,经过局部治疗和控制成功,在服用辉瑞生物技术公司的COVID-19疫苗后突然发作。第二例为57岁女性,既往高血压和甲状腺功能减退病史得到控制。在接种第三剂COVID - 19疫苗后出现新的扁平苔藓。第三次注射后3周出现病变。
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引用次数: 1
Public perception and willingness to undergo cosmetic procedures during the COVID-19 pandemic: A cross-sectional study COVID-19大流行期间公众接受整容手术的认知和意愿:一项横断面研究
Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_18_21
Ibrahim Alreshidi, Assil Albrekeit, Ruaa Alharithy
Background: As a result of the spread of coronavirus disease (COVID-19) at the beginning of 2020, many governments, including Saudi Arabia, have suspended operations in many agencies. Most of the dermatologists have restricted their practice, including cosmetic procedures, to ensure social distancing. On May 7, 2020, Saudi authorities have reduced the restriction of COVID-19 virus preventative measures, allowing clinics to start accepting patients with following the ministry of health protocols. Purpose: To evaluate the public's perception and willingness to undergo cosmetic procedures during the COVID-19 outbreaks in Saudi Arabia. Methods: A descriptive, cross-sectional, questionnaire-based study was carried out among the individuals who lack typical symptoms of COVID-19 infection in Saudi Arabia. A self-designed web-based questionnaire was developed; content face validity and a pilot study were done. The questionnaire was distributed electronically from May 8 to May 31, 2020. Results: A total of 656 individuals who lack typical symptoms of COVID-19 infection were included in this analysis. Only 10.5% of participants expressed their will to do cosmetic procedures during the COVID-19 pandemic. More than 90% of the participants believed that the COVID-19 pandemic was either somewhat serious (52.9%) or very serious (38.7%). The willingness to do cosmetic procedures during the COVID-19 pandemic remained unaltered when the price was discounted (P < 0.001), and when infection control measures were ensured (P < 0.001). Conclusion: The COVID-19 pandemic had a negative impact on the practice of cosmetic dermatology. Fear of transferring the infection to a beloved home member is the main reason to avoid these procedures. Generating well-structured safety guidelines to decrease the risk of this unusual virus transmission in dermatology practice and creating financial incentives may help increase the public willingness to do these cosmetic procedures during this pandemic.
背景:由于2019冠状病毒病(COVID-19)在2020年初的传播,包括沙特阿拉伯在内的许多国家政府暂停了许多机构的运作。大多数皮肤科医生都限制了他们的执业,包括整容手术,以确保社交距离。2020年5月7日,沙特当局减少了对COVID-19病毒预防措施的限制,允许诊所开始接受遵循卫生部协议的患者。目的:评估沙特阿拉伯2019冠状病毒病疫情期间公众接受整容手术的认知和意愿。方法:在沙特阿拉伯缺乏COVID-19感染典型症状的个体中开展了一项描述性、横断面、基于问卷的研究。自行设计了一份基于网络的问卷;内容面效度和初步研究。问卷于2020年5月8日至5月31日以电子方式发放。结果:共有656名缺乏COVID-19感染典型症状的个体被纳入该分析。只有10.5%的参与者表示愿意在COVID-19大流行期间进行整容手术。超过90%的受访者认为新冠肺炎大流行“比较严重”(52.9%)或“非常严重”(38.7%)。在COVID-19大流行期间,当价格打折(P < 0.001)和确保感染控制措施(P < 0.001)时,做美容手术的意愿保持不变。结论:2019冠状病毒病大流行对美容皮肤科执业产生了负面影响。害怕将感染传染给心爱的家庭成员是避免这些程序的主要原因。制定结构良好的安全指南,以降低皮肤科实践中这种不寻常病毒传播的风险,并制定财政激励措施,可能有助于提高公众在本次大流行期间进行这些美容手术的意愿。
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引用次数: 0
Postmessenger ribonucleic acid COVID-19 vaccine delayed inflammatory reaction to dermal fillers: Case report 信使核糖核酸COVID-19疫苗延迟皮肤填充物的炎症反应:1例报告
Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_114_21
Ruaa Alharithy, A. Alsaedi, Marwan Alsaedi
We report two cases of inflammatory reaction to postvaccination to Pfizer COVID-19 vaccine from Saudi Arabia: A case of delayed inflammatory reactions (DIRs) to hyaluronic acid (HA) dermal filler in the upper lip following the first dose of messenger ribonucleic acid Pfizer-BioNTech COVID-19 vaccine; the second case of DIR to HA filler underneath of eye following the second dose of Pfizer COVID-19 vaccine. The mechanism of this late reaction to HA fillers may be dependent on numerous factors and is not well understood.
我们报告了两例来自沙特阿拉伯的辉瑞COVID-19疫苗接种后的炎症反应:1例在首次接种信使核糖核酸辉瑞biontech COVID-19疫苗后,上唇对透明质酸(HA)真皮填充物的延迟炎症反应(DIRs);第2次辉瑞COVID-19疫苗接种后第2例眼下DIR转HA填充物。这种对HA填充物的晚期反应的机制可能取决于许多因素,但尚未得到很好的理解。
{"title":"Postmessenger ribonucleic acid COVID-19 vaccine delayed inflammatory reaction to dermal fillers: Case report","authors":"Ruaa Alharithy, A. Alsaedi, Marwan Alsaedi","doi":"10.4103/jdds.jdds_114_21","DOIUrl":"https://doi.org/10.4103/jdds.jdds_114_21","url":null,"abstract":"We report two cases of inflammatory reaction to postvaccination to Pfizer COVID-19 vaccine from Saudi Arabia: A case of delayed inflammatory reactions (DIRs) to hyaluronic acid (HA) dermal filler in the upper lip following the first dose of messenger ribonucleic acid Pfizer-BioNTech COVID-19 vaccine; the second case of DIR to HA filler underneath of eye following the second dose of Pfizer COVID-19 vaccine. The mechanism of this late reaction to HA fillers may be dependent on numerous factors and is not well understood.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"111 1","pages":"48 - 50"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85276480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Trichoscopic findings in various alopecias at tertiary referral center: A cross-sectional study 三级转诊中心各种脱发的毛发镜检查结果:一项横断面研究
Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_47_21
Mamatha P, V. Neha, Shishira R. Jartarkar, S. Sampath, Rakesh Madireddy
Background: Hair disorders are a common complaint that baffles dermatologists due to multiple causes. Trichoscopy is a noninvasive technique used to diagnose and monitor the progression of various hair disorders. Purpose: To observe the trichoscopic patterns of various hair disorders to assist with differentiation. Methods: This was a cross-sectional observational study done in 256 patients with alopecia. After a detailed history, clinical examination, and relevant investigations, trichoscopy was performed using a Dermlite (3Gen LLC, Sanjuan Capistrano, CA, USA) dermoscope. Results: Out of 256 patients, 154 were male and 102 were female. Most of the cases were in the age group of 21–40 years (66.4%). Nonscarring alopecias (93.35%) were common compared to scarring alopecias (5.8%). The most common alopecia noted in our study was Androgenetic alopecia 125 patients (48.82%), followed by telogen effluvium 48 patients (19.1%), the common trichoscopic follicular features noted were short vellus hair 161 (62.8%), yellow dots (61%), hair diameter variation 125 (48.82%), and black dots (21.87%). The commo interfollicular features are seen were arborizing vessels 109 (42.6%) and pigmentation in 12 patients (4.68%). Significant findings observed in each group were hair diameter diversity in androgenetic alopecia, exclamatory mark in Alopecia Areata, comma hair in tinea capitis. Cicatricial alopecias are characterized by loss of follicular ostia along with inflammatory signs such as perifollicular scales and casts. Conclusion: Trichoscopy is a very valuable and useful tool to diagnose various hair disorders by understanding the various trichoscopic patterns specific for each disease.
背景:由于多种原因,头发疾病是困扰皮肤科医生的常见疾病。毛发镜检查是一种非侵入性技术,用于诊断和监测各种头发疾病的进展。目的:观察各种发性疾病的毛发镜形态,以帮助鉴别。方法:这是一项对256例脱发患者进行的横断面观察性研究。在详细的病史、临床检查和相关调查后,使用Dermlite (3Gen LLC, Sanjuan Capistrano, CA, USA)皮肤镜进行毛发镜检查。结果:256例患者中,男性154例,女性102例。以21 ~ 40岁年龄组居多(66.4%)。非瘢痕性脱发(93.35%)较瘢痕性脱发(5.8%)更为常见。本研究中最常见的脱发是雄激素性脱发125例(48.82%),其次是休止期脱发48例(19.1%),常见的毛囊特征是短绒毛161例(62.8%),黄点(61%),头发直径变化125例(48.82%),黑点(21.87%)。常见的滤泡间征为树枝状血管109例(42.6%),色素沉着12例(4.68%)。各组在雄激素源性脱发、斑秃、头癣等方面均有显著差异。瘢痕性脱发的特点是滤泡口缺失,并伴有炎性征象,如滤泡周围鳞片和铸型。结论:毛发镜检查是一种非常有价值和有用的工具,可以通过了解每种疾病的不同的毛发检查模式来诊断各种头发疾病。
{"title":"Trichoscopic findings in various alopecias at tertiary referral center: A cross-sectional study","authors":"Mamatha P, V. Neha, Shishira R. Jartarkar, S. Sampath, Rakesh Madireddy","doi":"10.4103/jdds.jdds_47_21","DOIUrl":"https://doi.org/10.4103/jdds.jdds_47_21","url":null,"abstract":"Background: Hair disorders are a common complaint that baffles dermatologists due to multiple causes. Trichoscopy is a noninvasive technique used to diagnose and monitor the progression of various hair disorders. Purpose: To observe the trichoscopic patterns of various hair disorders to assist with differentiation. Methods: This was a cross-sectional observational study done in 256 patients with alopecia. After a detailed history, clinical examination, and relevant investigations, trichoscopy was performed using a Dermlite (3Gen LLC, Sanjuan Capistrano, CA, USA) dermoscope. Results: Out of 256 patients, 154 were male and 102 were female. Most of the cases were in the age group of 21–40 years (66.4%). Nonscarring alopecias (93.35%) were common compared to scarring alopecias (5.8%). The most common alopecia noted in our study was Androgenetic alopecia 125 patients (48.82%), followed by telogen effluvium 48 patients (19.1%), the common trichoscopic follicular features noted were short vellus hair 161 (62.8%), yellow dots (61%), hair diameter variation 125 (48.82%), and black dots (21.87%). The commo interfollicular features are seen were arborizing vessels 109 (42.6%) and pigmentation in 12 patients (4.68%). Significant findings observed in each group were hair diameter diversity in androgenetic alopecia, exclamatory mark in Alopecia Areata, comma hair in tinea capitis. Cicatricial alopecias are characterized by loss of follicular ostia along with inflammatory signs such as perifollicular scales and casts. Conclusion: Trichoscopy is a very valuable and useful tool to diagnose various hair disorders by understanding the various trichoscopic patterns specific for each disease.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"173 1","pages":"25 - 30"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76652903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurotic excoriation presenting as solitary papule: Case report 神经性瘙痒表现为孤立丘疹:1例报告
Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_59_21
Rawan A Aldhahwani, K. A. Al Hawsawi
Neurotic excoriation (NE) is a repetitive manipulation of the skin that causes tissue damage. Here, we report on a 56-year-old male, otherwise healthy, who presented with a 1-year history of a recurrent slightly itchy skin lesion on his nose. Skin examination revealed a solitary round 0.5 cm × 0.5 cm pigmented crusted papule on his nose. A skin biopsy was taken, and it showed an epidermal crust with underlying mild inflammatory cell infiltrate in the upper dermis. On the basis of these clinical and pathological findings, the diagnosis of NE was made. The patient was reassured and prescribed Fucidin cream and betamethasone valerate ointment. Behavioral therapy was also initiated.
神经性剥除(NE)是一种反复的皮肤操作,导致组织损伤。在这里,我们报告一个56岁的男性,其他方面健康,谁提出了1年的历史,反复轻微瘙痒的皮肤病变在他的鼻子。皮肤检查:鼻部见一孤立圆形0.5 cm × 0.5 cm色素结痂丘疹。皮肤活检显示表皮结痂,真皮上部有潜在的轻度炎症细胞浸润。根据这些临床和病理表现,诊断为NE。病人得到安慰后,开了氟哌酸乳膏和戊酸倍他米松软膏。行为治疗也开始了。
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引用次数: 0
Recurrent papulonecrotic tuberculid in an adolescent male: A diagnostic dilemma 青少年男性复发性丘疹性坏死结核:诊断困境
Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_5_22
Arundhathi Shankaralingappa, M. Anthony, T. Santosh, K. Josephain, Prabhakaran Nagendran, Hima Gopinath
Tuberculids are considered to be a hypersensitivity reaction to endogenous tuberculosis (TB). Papulonecrotic tuberculid (PNT) is a rare tuberculid occurring in <5% of active TB. An 18-year-old male presented with recurrent necrotic papules for 6 years on limbs, trunk, and neck which healed with scars. Biopsy from lesion revealed caseating granulomas with lymphohistiocytic vasculitis. Ziehl–Neelsen stain was negative for acid-fast bacilli, but Mantoux was strongly positive. The polymerase chain reaction was not done due to monetary constraints. The final diagnosis of PNT was confirmed and he was started on anti-tubercular treatment (ATT) for which he responded. PNT should be treated as a sentinel lesion and a meticulous search for systemic involvement of TB should be carried out. Awareness about PNT is essential for its diagnosis and to institute ATT at appropriate time.
结核被认为是对内源性结核(TB)的超敏反应。丘疹坏死结核(PNT)是一种罕见的结核,发生率<5%的活动性结核。一位18岁的男性,在四肢、躯干和颈部复发性坏死性丘疹6年,愈合后伴有疤痕。病变活检显示干酪样肉芽肿伴淋巴组织细胞性血管炎。Ziehl-Neelsen染色抗酸杆菌阴性,Mantoux染色强阳性。由于资金限制,聚合酶链反应没有进行。最终确诊为PNT,患者开始接受抗结核治疗(ATT),治疗有效果。PNT应作为前哨病变来治疗,并应仔细检查是否累及全身结核。对PNT的认识对其诊断和在适当的时候建立ATT至关重要。
{"title":"Recurrent papulonecrotic tuberculid in an adolescent male: A diagnostic dilemma","authors":"Arundhathi Shankaralingappa, M. Anthony, T. Santosh, K. Josephain, Prabhakaran Nagendran, Hima Gopinath","doi":"10.4103/jdds.jdds_5_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_5_22","url":null,"abstract":"Tuberculids are considered to be a hypersensitivity reaction to endogenous tuberculosis (TB). Papulonecrotic tuberculid (PNT) is a rare tuberculid occurring in <5% of active TB. An 18-year-old male presented with recurrent necrotic papules for 6 years on limbs, trunk, and neck which healed with scars. Biopsy from lesion revealed caseating granulomas with lymphohistiocytic vasculitis. Ziehl–Neelsen stain was negative for acid-fast bacilli, but Mantoux was strongly positive. The polymerase chain reaction was not done due to monetary constraints. The final diagnosis of PNT was confirmed and he was started on anti-tubercular treatment (ATT) for which he responded. PNT should be treated as a sentinel lesion and a meticulous search for systemic involvement of TB should be carried out. Awareness about PNT is essential for its diagnosis and to institute ATT at appropriate time.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"142 1","pages":"51 - 53"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77408285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin cleansing and wound care practice in patients with epidermolysis bullosa: A cross-sectional study 大疱性表皮松解症患者的皮肤清洁和伤口护理实践:一项横断面研究
Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_99_21
Ashjan Alheggi, L. Alzakry, R. Khunayn, Rahaf I. Alshareef, Yara Al-Khalid
Background: Epidermolysis bullosa (EB) is a group of genodermatoses characterized by fragile skin that may progress to erosions, blisters, and open nonhealing wounds. Understanding home skincare practices and topical products use among patients with EB is necessary to optimize management outcomes and quality of life. Purpose: The purpose of this study was to assess home bathing, skincare routines, and topical product used in patients with EB. Methods: Cross-sectional, observational study data were collected from patient-directed questionnaires in the Saudi EB registry. Data collection and statistical analyses were conducted using Microsoft Excel and SPSS-V.25. Results: Thirty-seven patients (62% males; mean age 14; [2 months–36] years) were enrolled. EB subtypes included EB simplex (n = 13), junctional EB (n = 6), and dystrophic EB (n = 13); five patients had unknown type. Twenty-one patients (57%) dislike multilayer wound dressings and/or find that they exacerbate the blistering during summer and in hot climates. Almost one-quarter of participants reported lancing a few of the intact blisters, and 5.4% did not lance any. Bath additives ranged from barely effective to potentially cytotoxic solutions of vinegar and sodium hypochlorite solution. Around 1/3rd of participants reported the use of topical antibiotics with no alternation or rotation on dirty wounds, and 8.1% of our cohort reported the use of antibiotics on intact skin. Conclusion: Education is needed for EB patients and their families on lancing of blisters and topical antibiotic use, especially in light of increasing antibiotic resistance. Dressing modification for EB patients living in the Gulf region countries, particularly during hot and humid months, may be helpful.
背景:大疱性表皮松解症(EB)是一组以皮肤脆弱为特征的遗传性皮肤病,可发展为糜烂、水泡和开放的不愈合伤口。了解EB患者的家庭护肤实践和局部产品的使用对于优化管理结果和生活质量是必要的。目的:本研究的目的是评估家庭沐浴、护肤程序和外用产品在EB患者中的应用。方法:横断面观察性研究数据收集自沙特EB登记处的患者导向问卷。使用Microsoft Excel和SPSS-V.25软件进行数据收集和统计分析。结果:37例患者(男性62%;平均年龄14岁;[2个月- 36]年]。EB亚型包括单纯型EB (n = 13)、交界型EB (n = 6)和营养不良型EB (n = 13);5例患者类型不明。21名患者(57%)不喜欢多层伤口敷料和/或发现它们在夏季和炎热气候下加剧了起泡。近四分之一的参与者报告说,他们刺破了几个完整的水泡,5.4%的人没有刺破任何水泡。浴液添加剂的范围从几乎没有效果到有潜在细胞毒性的醋溶液和次氯酸钠溶液。大约1/3的参与者报告说,在肮脏的伤口上不交替或轮流使用局部抗生素,我们的队列中有8.1%的人报告说,在完整的皮肤上使用抗生素。结论:对EB患者及其家属进行水疱剥落和局部抗生素使用的教育是必要的,特别是在抗生素耐药性日益增加的情况下。对于生活在海湾地区国家的EB患者,特别是在炎热潮湿的月份,换药可能会有所帮助。
{"title":"Skin cleansing and wound care practice in patients with epidermolysis bullosa: A cross-sectional study","authors":"Ashjan Alheggi, L. Alzakry, R. Khunayn, Rahaf I. Alshareef, Yara Al-Khalid","doi":"10.4103/jdds.jdds_99_21","DOIUrl":"https://doi.org/10.4103/jdds.jdds_99_21","url":null,"abstract":"Background: Epidermolysis bullosa (EB) is a group of genodermatoses characterized by fragile skin that may progress to erosions, blisters, and open nonhealing wounds. Understanding home skincare practices and topical products use among patients with EB is necessary to optimize management outcomes and quality of life. Purpose: The purpose of this study was to assess home bathing, skincare routines, and topical product used in patients with EB. Methods: Cross-sectional, observational study data were collected from patient-directed questionnaires in the Saudi EB registry. Data collection and statistical analyses were conducted using Microsoft Excel and SPSS-V.25. Results: Thirty-seven patients (62% males; mean age 14; [2 months–36] years) were enrolled. EB subtypes included EB simplex (n = 13), junctional EB (n = 6), and dystrophic EB (n = 13); five patients had unknown type. Twenty-one patients (57%) dislike multilayer wound dressings and/or find that they exacerbate the blistering during summer and in hot climates. Almost one-quarter of participants reported lancing a few of the intact blisters, and 5.4% did not lance any. Bath additives ranged from barely effective to potentially cytotoxic solutions of vinegar and sodium hypochlorite solution. Around 1/3rd of participants reported the use of topical antibiotics with no alternation or rotation on dirty wounds, and 8.1% of our cohort reported the use of antibiotics on intact skin. Conclusion: Education is needed for EB patients and their families on lancing of blisters and topical antibiotic use, especially in light of increasing antibiotic resistance. Dressing modification for EB patients living in the Gulf region countries, particularly during hot and humid months, may be helpful.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"16 1","pages":"13 - 17"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89352111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Burnout syndrome in dermatology residents: A cross-sectional study 皮肤科住院医师的职业倦怠综合征:一项横断面研究
Pub Date : 2022-01-01 DOI: 10.4103/jdds.jdds_69_21
Asem M. Shadid, Batal M. Aldosari, A. Algarni, A. Dahmash, Saad Altalhab, Ruaa Alharithy
Background: Burnout is defined by three dimensions: emotional exhaustion (EE), depersonalization (DP), and low personal feelings of achievement (PA). It is a prolonged response to chronic emotional and interpersonal stressors on the job. If unrecognized, the costs to the health-care system can be enormous. Purpose: The aim of this study is to investigate the prevalence of burnout levels and predictors among dermatology residents and the risk factors associated with it. Methods: Validated measure of burnout (Maslach Burnout Inventory–Human Services Survey), alongside the possible risk factors of burnout, was distributed to all dermatology board training residents in all affiliated centers in Riyadh, Saudi Arabia. The response rate was 96.2% with 51 residents completing the survey out of 53. Results: High EE was present in 41.2% of dermatology residents, a low sense of PA in 45.1%, while high DP was the least prevalent at 13.7%. Satisfaction with career was significantly associated with risk of high EE (odds ratios [OR] = 0.61, 95% Confidence interval [CI] = 0.15–22.3), risk of high DP (OR = 0.34, 95% CI = 0.08–0.316), and risk of low PA (OR = 0.86, 95% CI = 0.52–6.1). The average number of sleeping hours was also associated with risk of high EE (OR = 0.87, 95% CI = 0.54–3.88), risk of high DP (OR = 0.76, 95% CI = 0.5–1.41), and risk of low PA (OR = 0.86, 95% CI = 0.52–6.1). Our findings report high over all burnout in 7.8% of the respondents. Conclusion: EE and feelings of low PA were seen at a high rate among dermatology residents, while DP was the least prevalent across all burnout dimensions. Average daily sleeping hours alongside satisfaction with life/work balance, career, and salary showed a statistically significant association with DP, low PA, EE, and overall burnout. Protected time to pursue academic interests, for example, research and teaching, and a fair distribution of on-call hours per month, as well as a number of clinics per week may explain the rate of burnout in our study. These findings can be applied in the improvement of training programs to reduce the burnout rate among residents.
背景:职业倦怠由三个维度定义:情绪耗竭(EE)、人格解体(DP)和低个人成就感(PA)。它是对工作中长期的情绪和人际压力的长期反应。如果不加以认识,卫生保健系统的成本可能是巨大的。目的:本研究旨在探讨皮肤科住院医师职业倦怠的患病率、预测因素及相关危险因素。方法:将经过验证的倦怠量表(Maslach倦怠量表-人类服务调查)以及可能的倦怠风险因素分发给沙特阿拉伯利雅得所有附属中心的所有皮肤科委员会培训住院医师。53名市民中有51人完成调查,回复率为96.2%。结果:41.2%的皮肤科居民存在高EE, 45.1%的人存在低PA感,而高DP的发生率最低,为13.7%。职业满意度与高情感表达风险(比值比[OR] = 0.61, 95%可信区间[CI] = 0.15-22.3)、高DP风险(OR = 0.34, 95% CI = 0.08-0.316)和低PA风险(OR = 0.86, 95% CI = 0.52-6.1)显著相关。平均睡眠时间也与高情感表达风险(OR = 0.87, 95% CI = 0.54-3.88)、高DP风险(OR = 0.76, 95% CI = 0.5-1.41)和低PA风险(OR = 0.86, 95% CI = 0.52-6.1)相关。我们的调查结果显示,7.8%的受访者的职业倦怠程度很高。结论:在皮肤科住院医师中,情感表达和低PA感觉的比例很高,而DP在所有倦怠维度中都是最不普遍的。平均每日睡眠时间以及对生活/工作平衡、职业和薪水的满意度与DP、低PA、EE和整体倦怠有统计学意义的关联。保护时间来追求学术兴趣,例如,研究和教学,每月随叫随到的公平分配时间,以及每周的一些诊所,可能解释了我们研究中的倦怠率。这些研究结果可用于改善培训计划,以降低住院医师的倦怠率。
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引用次数: 2
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Journal of Dermatology and Dermatologic Surgery
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