Journal of Dental Sciences最新文献

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Perspectives of the new horizon in bone regeneration with standardized, centrally manufactured freeze-dried platelet-rich plasma 标准化、中央制造的冻干富血小板血浆在骨再生中的新前景

IF 3.1 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Dental Sciences

Pub Date : 2025-08-16 DOI: 10.1016/j.jds.2025.08.008

Yi-Tzu Chen , Pei-Yin Chen , Yu-Chao Chang

引用次数: 0

Unexpected reversal of internal root resorption following tampon partial pulpotomy in irreversible pulpitis: Challenging endodontic dogma 不可逆性牙髓炎患者棉条部分截髓术后牙根吸收的意外逆转：挑战牙髓学教条

IF 3.1 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Dental Sciences

Pub Date : 2025-08-16 DOI: 10.1016/j.jds.2025.08.007

Saeed Asgary

引用次数: 0

Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in oral lichen planus patients with normocytosis 口腔扁平苔藓伴正常细胞增多症患者的贫血、血液病缺乏、高同型半胱氨酸血症和胃壁细胞抗体阳性

IF 3.1 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Dental Sciences

Pub Date : 2025-08-16 DOI: 10.1016/j.jds.2025.08.003

Julia Yu-Fong Chang , Yu-Hsueh Wu , Yi-Pang Lee , Yi-Ping Wang , Andy Sun , Chun-Pin Chiang

Background/purpose

Normocytosis is defined as having the mean corpuscular volume (MCV) between 80 fL and 99.9 fL. This study evaluated whether the 474 oral lichen planus (OLP) patients with normocytosis (so-called normocytosis/OLP patients) had significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity than 588 healthy control subjects or 588 OLP patients.

Materials and methods

Complete blood count, serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 588 OLP patients, 474 normocytosis/OLP patients, and 588 healthy control subjects were measured and compared.

Results

We found that 14.3 %, 12.7 %, 4.0 %, 1.5 %, 16.0 %, and 19.8 % of the 474 normocytosis/OLP patients had blood hemoglobin (Hb) and serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity, respectively. Furthermore, the 474 normocytosis/OLP patients had significantly higher frequencies of blood Hb and serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity than 588 healthy control subjects (all P-values <0.05). On the contrary, the 474 normocytosis/OLP patients had significantly lower frequencies of blood Hb and serum vitamin B12 deficiencies and hyperhomocysteinemia than the overall 588 OLP patients (all P-values <0.05).

Conclusion

We conclude that there are significantly higher frequencies of anemia, serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity in normocytosis/OLP patients than in healthy control subjects. On the contrary, normocytosis/OLP patients do have significantly lower frequencies of blood Hb and vitamin B12 deficiencies and hyperhomocysteinemia than overall OLP patients.

背景/目的细胞增多症被定义为平均红细胞体积（MCV）在80 fL到99.9 fL之间。本研究评估了474例口腔扁平苔藓（OLP）患者（所谓的正常细胞增多症/OLP患者）是否比588名健康对照者或588名OLP患者有明显更高的贫血、血液病缺乏、高同型半胱氨酸血症和血清胃壁细胞抗体（GPCA）阳性的频率。材料与方法测定588例OLP患者、474例正常细胞增多症/OLP患者和588例健康对照者全血细胞计数、血清铁、维生素B12、叶酸、同型半胱氨酸和GPCA水平并进行比较。结果474例正常细胞增多症/OLP患者中分别有14.3%、12.7%、4.0%、1.5%、16.0%和19.8%存在血红蛋白（Hb）、血清铁、维生素B12和叶酸缺乏、高同型半胱氨酸血症和血清GPCA阳性。此外，474例正常细胞增多症/OLP患者血Hb和血清铁、维生素B12和叶酸缺乏、高同型半胱氨酸血症和血清GPCA阳性的频率显著高于588例健康对照（p值均为0.05）。相反，474例正常细胞增多症/OLP患者的血Hb和血清维生素B12缺乏症和高同型半胱氨酸血症的频率明显低于总体588例OLP患者（p值均为0.05）。结论正常细胞增多症/OLP患者的贫血、血清铁、维生素B12和叶酸缺乏、高同型半胱氨酸血症和血清GPCA阳性发生率明显高于健康对照组。相反，正常细胞增多症/OLP患者的血Hb和维生素B12缺乏症以及高同型半胱氨酸血症的发生率明显低于整体OLP患者。

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引用次数: 0

Surgical removal of an asymptomatic radicular cyst after 10 years of follow-up 手术切除无症状的根状囊肿后10年的随访

IF 3.1 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Dental Sciences

Pub Date : 2025-08-16 DOI: 10.1016/j.jds.2025.08.005

Feng-Chou Cheng, Ching-En Meng, Pei-Yu Hsu, Chun-Pin Chiang

引用次数: 0

Postoperative carotid sinus syndrome presenting as sinus pause in an oral cancer patient: A rare but clinically significant case 口腔癌患者术后颈动脉窦综合征表现为窦暂停：一个罕见但具有临床意义的病例

IF 3.1 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Dental Sciences

Pub Date : 2025-08-14 DOI: 10.1016/j.jds.2025.07.025

Tzu-Hao Hsiao, Tung-Nien Hsu, Po Chih Hsu

引用次数: 0

Application model of reading the medical images from the National Health Insurance (NHI) MediCloud System for clinic dentists: A case report 临床牙医从医疗云系统中读取医学图像的应用模型：一例报告

IF 3.1 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Dental Sciences

Pub Date : 2025-08-14 DOI: 10.1016/j.jds.2025.08.004

Feng-Chou Cheng, Chia-Hua Shih, Yu-Jie Shen, Chun-Pin Chiang

引用次数: 0

Current challenges of the implementation of radiology diagnosis equipment operating license for the dentists in Taiwan 台湾牙医实施放射诊断设备操作执照之挑战

IF 3.1 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Dental Sciences

Pub Date : 2025-08-14 DOI: 10.1016/j.jds.2025.08.006

Feng-Chou Cheng, Yan-De Liou, Bo-Lin Liu, Chun-Pin Chiang

引用次数: 0

Simultaneous presentation of three types of osteoid osteoma in the maxilla 上颌同时出现三种骨样骨瘤

IF 3.1 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Dental Sciences

Pub Date : 2025-08-11 DOI: 10.1016/j.jds.2025.07.032

Jen-Ho Wen , Chen-Yu Heieh , Yang-Che Wu, Chih-Yuan Fang

引用次数: 0

In vitro evaluation of novel composite bioceramic filaments for alveolar bone regeneration 新型复合生物陶瓷丝牙槽骨再生的体外评价

IF 3.1 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Dental Sciences

Pub Date : 2025-08-11 DOI: 10.1016/j.jds.2025.07.012

Yu Ting Li , Ju-Hsuan Yang , Yu-Hsin Chang , Hao-Hueng Chang , Chun-Pin Lin

Background/purpose

Alveolar bone defect repair remains a major clinical challenge in oral and maxillofacial reconstruction. This study developed 3D-printable composite filaments combining polylactic acid (PLA) with bioceramic powders and evaluated their physicochemical properties and in vitro osteogenic potential for alveolar bone graft applications.

Materials and methods

Filaments were fabricated via hot processing and tetrahydrofuran (THF) solvent casting, blending PLA with hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP) at a 7:3 ratio. Four groups, H-PLA (heated PLA), H-MIX (heated PLA with HA/β-TCP), T-PLA (THF-processed PLA), and T-MIX (THF-processed PLA with HA/β-TCP) groups, underwent material characterization such as Fourier transform infrared spectroscopy (FTIR), X-ray diffractometer (XRD), scanning electron microscopy (SEM), and compressive strength testing, and MC3T3 cell-based assays for biocompatibility assessment.

Results

H-MIX and T-MIX significantly enhanced compressive strength and osteogenic mineralization compared to PLA-only groups. HA/β-TCP was uniformly dispersed within the PLA matrix. Cell proliferation peaked on day 3, with both composite groups showing higher viability than controls (P < 0.01). Alkaline phosphatase (ALP) activity increased by day 7, with T-MIX significantly higher than H-PLA and T-PLA (P < 0.05). On day 14, T-MIX and H-MIX showed markedly greater mineralization, with T-MIX displaying the highest calcium deposition (P < 0.05 to P < 0.001).

Conclusion

Composite scaffolds made by thermal and solvent casting showed enhanced mechanical strength and osteogenic activity in vitro. T-MIX outperformed other groups in compressive strength, ALP activity, and calcium deposition. These results indicate that HA/β-TCP-reinforced PLA filaments, especially T-MIX, are promising for alveolar bone repair.

背景/目的牙槽骨缺损修复是口腔颌面部重建的主要临床挑战。本研究开发了结合聚乳酸（PLA）和生物陶瓷粉末的3d打印复合长丝，并评估了其物理化学特性和体外成骨潜力，用于牙槽骨移植应用。材料和方法采用热加工和四氢呋喃（THF）溶剂铸造，PLA与羟基磷灰石（HA）和β-磷酸三钙（β-TCP）以7:3的比例共混制备长丝。四组，H-PLA（加热PLA）， H-MIX（加热PLA与HA/β-TCP）， T-PLA （thf处理PLA）和T-MIX （thf处理PLA与HA/β-TCP）组，进行了材料表征，如傅里叶变换红外光谱（FTIR）， x射线衍射仪（XRD），扫描电镜（SEM）和抗压强度测试，以及基于MC3T3细胞的生物相容性评估。结果与纯pla组相比，sh - mix和T-MIX可显著提高抗压强度和成骨矿化。HA/β-TCP均匀分散在PLA基质中。细胞增殖在第3天达到高峰，两组细胞活力均高于对照组（P < 0.01）。第7天碱性磷酸酶（ALP）活性升高，T-MIX显著高于H-PLA和T-PLA （P < 0.05）。第14天，T-MIX和H-MIX的矿化程度显著提高，其中T-MIX钙沉积最高（P < 0.05 ~ P < 0.001）。结论热铸造和溶剂铸造复合支架具有较强的机械强度和体外成骨活性。T-MIX在抗压强度、ALP活性和钙沉积方面优于其他组。这些结果表明，HA/β- tcp -增强PLA长丝，特别是T-MIX，在牙槽骨修复中具有很好的应用前景。

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引用次数: 0

Endodontic treatment and anxiety: Exploring cortisol-driven stress mechanisms 牙髓治疗与焦虑：探索皮质醇驱动的应激机制

IF 3.1 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Dental Sciences

Pub Date : 2025-08-11 DOI: 10.1016/j.jds.2025.07.030

Wesley Viana, Silmara Silva, Christianne Velozo, Diana Albuquerque

引用次数: 0

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