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The application of quantum dots in dental and oral medicine: A scoping review 量子点在口腔医学中的应用综述
IF 4.8 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.jdent.2024.105536
Yuchen Liu , Nannan Wang , Danchen Qin , Xiaohui Chen , Hongye Yang , Fang Hua

Objectives

To present an overview of quantum dots’ (QDs) applications in dental and oral medicine, identify research gaps in existing relevant research, and provide insights into future research.

Data and sources

An extensive electronic search was conducted across five databases from their inception to April 2024, complemented by a manual search. There were no restrictions regarding language or publication year.

Study selection

Out of 2,483 records identified, 87 studies were included for analysis. The first application of QDs in dentistry was to use their bioimaging capabilities, which is their most well-known functionalities in the biomedical area. In the last 5 years, the number of studies has increased (n = 52), while the study areas have gradually broadened, demonstrating its unique form of application in dentistry. Included studies span seven key areas: bioimaging (n = 21), antibacterial effect (n = 20), tooth restoration (n = 15), oral cancer therapy (n = 12), tissue engineering (n = 10), biosensing (n = 6), and anti-inflammation (n = 3). Amongst the included studies, carbon-based QDs received the greatest attention (n = 54), owing to their excellent biocompatibility and readily functionalizable surface.

Conclusions/Clinical significance

This review emphasizes the great potential of QDs in enhancing the quality and efficiency of dental clinical diagnosis and treatment. They not only show the possibility of applications beyond the traditional function, but also provide a completely new concept for improving oral disease diagnosis and treatment technology. However, successful clinical translation requires ongoing research and optimization, which is a critical process.
目的:综述量子点(QDs)在口腔医学中的应用,找出现有相关研究的不足,并对未来的研究提出见解。数据和来源:从数据库建立到2024年4月,对五个数据库进行了广泛的电子检索,并辅以人工检索。对语言或出版年份没有限制。研究选择:在确定的2483份记录中,有87份研究被纳入分析。量子点在牙科中的第一个应用是利用它们的生物成像能力,这是它们在生物医学领域最著名的功能。近5年来,研究数量有所增加(n = 52),研究领域也逐渐拓宽,在牙科领域的应用呈现出独特的形式。包括研究跨越七个关键领域:bioimaging (n = 21),抗菌效果(n = 20),牙齿修复(n = 15),口腔癌症治疗(n = 12),组织工程(n = 10),若(n = 6),和抗炎(n = 3)。在这些研究中,碳基量子点由于其良好的生物相容性和易于功能化的表面而受到了最大的关注(n = 54)。结论/临床意义:本文强调量子点在提高口腔临床诊疗质量和效率方面的巨大潜力。它们不仅展示了超越传统功能的应用可能性,而且为提高口腔疾病的诊断和治疗技术提供了一个全新的概念。然而,成功的临床翻译需要不断的研究和优化,这是一个关键的过程。
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引用次数: 0
Clinical Outcomes of Novel CAD/CAM-Designed Functional Space Maintainers Produced via Additive and Subtractive Methods: A randomized controlled trial.
IF 4.8 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.jdent.2025.105608
Andrija Nedeljkovic, Marko Milosavljevic, Kristina Mladenovic, Vladimir Janjic, Martin Schimmel, Rasa Mladenovic

Objective: Since passive fixed space maintainers do not restore the lost tooth or provide chewing function, this study seeks to assess the effectiveness of an innovative approach for maintaining space following the premature extraction of first primary molars, utilizing functional space maintainers designed with CAD/CAM.

Methods: This randomized controlled trial included 28 patients into two groups, 15 in 3D Print and 13 in Milling. The inclusion criteria required extraction or loss of the first primary molar due to complications of caries, with a prolonged period until eruption of the successor. Space maintainers were fabricated using 3D printing metal (Co 69%, Cr 25%, W 9.5%, Mo 3.5%, Si 1%, Scheftner, Germany) and milling composite (breCAM.HIPC, Bredent, Germany). This study evaluated the efficiency of space maintainers through clinical check-ups at one, three, and six months, maximum occlusal bite force, and masticatory performance assessments.

Results: A positive clinical trend was noted over time, with the "type of space maintainer" factor (Milling vs. 3D Print) influencing the degree of clinical assessment (p < 0.001). There were no significant differences in maximum occlusal bite force between sides for both types of space maintainers (p = 0.270 for 3D Print and p = 0.765 for Milling). Significant improvements were observed in masticatory performance after the placement of both types of space maintainers.

Conclusion: A six-month follow-up showed that 3D-printed metal outperformed milled composite ones, with no significant differences in bite force or masticatory performance, indicating that CAD/CAM technology could set new standards in producing functional space maintainers.

Clinical significance: This study underscores the potential of these technologies to set new standards in pediatric dentistry, particularly for maintaining space following premature tooth loss, while ensuring improved functional outcomes for young patients.

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引用次数: 0
Automated dental registration and TMJ segmentation for virtual surgical planning of orthognathic surgery via three-step computer-based method 通过基于计算机的三步法为正颌外科手术的虚拟手术规划自动进行牙齿注册和颞下颌关节分割。
IF 4.8 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.jdent.2024.105443
Zhaokun Zhu , Zhen Liu , Liwei Huang, Hanghang Liu, Yao Liu, En Luo

Objective

This study developed and evaluated a computer-based method for automating the registration of scanned dental models with 3D reconstructed skulls and segmentation of the temporomandibular joint (TMJ).

Methods

A dataset comprising 1274 skull models and corresponding scanned dental models was collected. In total, 1066 cases were used for the development of the computer-based method, while 208 cases were used for validation. Performance was evaluated by comparing the automated results with manual registration and segmentation performed by clinicians, using accuracy and completeness metrics (e.g. intersection of union [IoU] and Dice similarity coefficient [DSC]).

Results

The automated registration achieved a mean absolute error of 0.35 mm for the maxilla and 0.38 mm for the mandible, and a root mean squared error of 0.46 mm and 0.39 mm, respectively. The automatic TMJ segmentation exhibited an accuracy of 97.48 %, a precision of 97.06 %, a IoU of 95.72 %, DSC of 97.3 %, and a Hausdorff value of 1.87 mm, which were sufficient for clinical application.

Conclusion

The proposed method significantly improved the efficiency of orthognathic surgical planning by automating the registration and segmentation processes. The accuracy and precision of the automated results were sufficient for clinical use, reducing the workload on clinicians and facilitating faster and more reliable surgical planning.

Clinical significance

The computer-based method streamlines orthognathic surgical planning, enhancing precision and efficiency without compromising clinical accuracy, ultimately improving patient outcomes and reducing the workload of surgeons.
目的:本研究开发并评估了一种基于计算机的方法,用于将扫描的牙科模型与三维重建的头骨进行自动配准,并对颞下颌关节进行分割:本研究开发并评估了一种基于计算机的方法,用于将扫描的牙科模型与三维重建的头骨进行自动配准,并对颞下颌关节(TMJ)进行分割:方法:收集了由 1274 个头骨模型和相应的扫描牙科模型组成的数据集。共有 1066 个病例用于开发基于计算机的方法,208 个病例用于验证。通过使用准确性和完整性指标(如联合交点 [IoU] 和 Dice 相似性系数 [DSC])将自动结果与临床医生进行的手动配准和分割进行比较,对性能进行评估:自动配准的平均绝对误差分别为:上颌骨 0.35 毫米,下颌骨 0.38 毫米,均方根误差分别为 0.46 毫米和 0.39 毫米。颞下颌关节自动分割的准确度为 97.48%,精确度为 97.06%,IoU 为 95.72%,DSC 为 97.3%,Hausdorff 值为 1.87 mm,足以满足临床应用的需要:结论:所提出的方法通过实现注册和分割过程的自动化,极大地提高了正颌外科手术规划的效率。结论:所提出的方法通过自动注册和分割过程,大大提高了正颌外科手术规划的效率,自动结果的准确性和精确性足以满足临床应用的需要,减轻了临床医生的工作量,有利于更快、更可靠地制定手术规划:临床意义:基于计算机的方法简化了正颌外科手术规划,在不影响临床准确性的前提下提高了精确度和效率,最终改善了患者的治疗效果,减轻了外科医生的工作量。
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引用次数: 0
Assessment of clinical reproducibility for intraoral scanning on different anatomical regions for the complete maxillary edentulous arch with two intraoral scanners 使用两台口内扫描仪对完整上颌无牙弓的不同解剖区域进行口内扫描的临床重现性评估。
IF 4.8 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.jdent.2024.105485
Andrew B. Cameron , Menaka A. Abuzar , Santosh Kumar Tadakamadla , Jane L. Evans

Objectives

There are no in vivo studies comparing multiple intraoral scanners (IOSs) for the completely edentulous maxilla to polyvinyl siloxane (PVS) impressions. Investigations comparing IOSs to PVS impressions focus on comparing the overall scan and not individual anatomical regions. This study aims to evaluate two IOSs and compare the results for different anatomical regions on the completely edentulous maxillary arch.

Materials and methods

Nineteen patients were recruited with a completely edentulous maxilla. A custom tray was constructed, and a sectional border moulded PVS impression was made then scanned. An intraoral scan of the edentulous maxilla with a Trios 4 (3Shape, B/V) and Medit i700 (Medit corporation) was then captured. The scans were analysed for negative and positive surface deviations along with root mean square for distinct anatomical regions compared to the polyvinyl siloxane impression. A two-way ANOVA followed by Tukey HSD post hoc tests for each scanner was conducted for all anatomical regions to determine differences between the regions.

Results

There was no significant difference between the two IOSs included in this study for all anatomical regions or for the overall scan (0.435, 0.38), palatal vault (0.18, 0.181), ridge (0.218, 0.209), and post dam (0.233, 0.229) anatomical regions. Significantly higher deviation (p < 0.05) was observed for the peripheral regions (0.607, 0.557) for each intraoral scanners Trio 4 and Medit i700.

Conclusion

Different IOSs can capture all areas of a completely edentulous maxilla consistently, when compared to a PVS impression, apart from the peripheries.

Clinical significance

Care should be taken when scanning the peripheries. These regions are problematic to capture with an IOS. Border moulding should still be considered the optimal impression technique for the completely edentulous maxilla. The IOSs investigated did not make a difference for the anatomical regions investigated.
目的:目前还没有对完全无牙上颌骨的多种口内扫描仪与聚乙烯硅氧烷印模进行比较的活体研究。将口内扫描仪与聚乙烯硅氧烷印模进行比较的研究侧重于比较整体扫描,而不是个别解剖区域。本研究旨在评估两种口内扫描仪,并比较完全无牙颌弓不同解剖区域的扫描结果:招募了 19 名上颌全缺失患者。制作了一个定制托盘,并制作了一个分段边界模制聚乙烯硅氧烷印模,然后进行扫描。然后用 Trios 4(3Shape,B/V)和 Medit i700(Medit 公司)对无牙上颌骨进行口内扫描。与聚乙烯硅氧烷印模相比,扫描结果分析了不同解剖区域的负表面偏差和正表面偏差以及均方根。对每个扫描仪的所有解剖区域进行双向方差分析,然后进行 Tukey HSD 事后检验,以确定各区域之间的差异:本研究中的两种口内扫描仪在所有解剖区域或整体扫描(0.435, 0.38)、腭穹(0.18, 0.181)、嵴(0.218, 0.209)和坝后(0.233, 0.229)解剖区域方面均无明显差异。偏差显著较高(p结论:与聚乙烯硅氧烷印模相比,不同的口内扫描仪可以一致地捕捉完全无牙颌的所有区域,除了边缘区域:临床意义:扫描边缘时应小心谨慎。临床意义:在扫描边缘时应小心,这些区域很难用口内扫描仪捕捉到。对于全口无牙的上颌骨,边模仍然是最佳的印模技术。所研究的口内扫描仪对所研究的解剖区域没有影响。
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引用次数: 0
Comparative accuracy of dCAIS and freehand techniques for immediate implant placement in the maxillary aesthetic zone: An in vitro study dCAIS与徒手技术在上颌美学区即刻种植体放置的比较准确性:一项体外研究。
IF 4.8 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.jdent.2024.105472
Markus Neuschitzer , Jorge Toledano-Serrabona , Adrià Jorba-García , J․Javier Bara-Casaus , Rui Figueiredo , Eduard Valmaseda-Castellón

Objective

To evaluate the accuracy of immediate implant placement in fresh extraction sockets in the maxillary aesthetic zone using a dynamic computer-assisted implant surgery system (dCAIS), with the evaluation of possible deviations versus freehand placement.

Methods

A total of 18 implants were placed by an experienced surgeon in fresh extraction sockets of anterior teeth in 6 maxillary models. Nine implants were placed using the dCAIS system and 9 implants were placed using the conventional freehand technique. The following outcome parameters were measured and compared: positional deviation at entry, apex point and angular deviations between planned and placed implant position. Surgery time was measured for each procedure. Descriptive and statistical analyses were performed on all outcome parameters.

Results

Global entry deviations were not significantly different between the two techniques (p = 0.078). dCAIS resulted in significantly more accurate implant placement in terms of global apex deviation with values of 1.28±0.36 mm and angular deviations with values of 1.29±0.64°, compared to 2.06±0.60 mm and 5.05±2.54° with freehand placement (p < 0.001). The dental implant placement time was approximately three times longer when using dCAIS (10.99 ± 3.43 min) versus freehand (3.25± 0.63 min) (p < 0.001).

Conclusions

dCAIS achieved more precise immediate implant placement in terms of apex deviation and angulation than freehand placement, but increased the surgery time.

Clinical significance

dCAIS provides greater accuracy in the placement of immediate implants in the maxillary aesthetic zone following prosthetic-driven digital planning compared to freehand surgery.
目的:评价动态计算机辅助种植手术系统(dCAIS)在上颌美观区新鲜拔牙槽即刻种植的准确性,并评估与徒手种植相比可能出现的偏差。方法:由经验丰富的外科医生在6例上颌模型前牙新鲜拔牙槽内放置18颗种植体。采用dCAIS系统放置9个种植体,采用传统徒手技术放置9个种植体。测量并比较以下结果参数:入口位置偏差、顶点位置偏差以及计划种植体和放置种植体位置之间的角度偏差。测量每次手术的手术时间。对所有结局参数进行描述性和统计学分析。结果:两种技术的整体入路偏差无显著差异(p=0.078)。与徒手放置相比,dCAIS在种植体总尖偏差(1.28±0.36 mm)和角度偏差(1.29±0.64°)上的放置精度明显高于徒手放置(2.06±0.60 mm)和(5.05±2.54°)(结论:dCAIS在种植体尖偏差和角度上比徒手放置更精确,但增加了手术时间。临床意义:与徒手手术相比,dCAIS在义肢驱动的数字规划下在上颌美观区提供了更高的即刻种植体放置准确性。
{"title":"Comparative accuracy of dCAIS and freehand techniques for immediate implant placement in the maxillary aesthetic zone: An in vitro study","authors":"Markus Neuschitzer ,&nbsp;Jorge Toledano-Serrabona ,&nbsp;Adrià Jorba-García ,&nbsp;J․Javier Bara-Casaus ,&nbsp;Rui Figueiredo ,&nbsp;Eduard Valmaseda-Castellón","doi":"10.1016/j.jdent.2024.105472","DOIUrl":"10.1016/j.jdent.2024.105472","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the accuracy of immediate implant placement in fresh extraction sockets in the maxillary aesthetic zone using a dynamic computer-assisted implant surgery system (dCAIS), with the evaluation of possible deviations versus freehand placement.</div></div><div><h3>Methods</h3><div>A total of 18 implants were placed by an experienced surgeon in fresh extraction sockets of anterior teeth in 6 maxillary models. Nine implants were placed using the dCAIS system and 9 implants were placed using the conventional freehand technique. The following outcome parameters were measured and compared: positional deviation at entry, apex point and angular deviations between planned and placed implant position. Surgery time was measured for each procedure. Descriptive and statistical analyses were performed on all outcome parameters.</div></div><div><h3>Results</h3><div>Global entry deviations were not significantly different between the two techniques (<em>p</em> = 0.078). dCAIS resulted in significantly more accurate implant placement in terms of global apex deviation with values of 1.28±0.36 mm and angular deviations with values of 1.29±0.64°, compared to 2.06±0.60 mm and 5.05±2.54° with freehand placement (<em>p</em> &lt; 0.001). The dental implant placement time was approximately three times longer when using dCAIS (10.99 ± 3.43 min) versus freehand (3.25± 0.63 min) (<em>p</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>dCAIS achieved more precise immediate implant placement in terms of apex deviation and angulation than freehand placement, but increased the surgery time.</div></div><div><h3>Clinical significance</h3><div>dCAIS provides greater accuracy in the placement of immediate implants in the maxillary aesthetic zone following prosthetic-driven digital planning compared to freehand surgery.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"153 ","pages":"Article 105472"},"PeriodicalIF":4.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thermographic images for screening oral health problems in older adults: A pilot study 用于筛查老年人口腔健康问题的热成像图像:一项试点研究。
IF 4.8 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.jdent.2024.105506
Angela Stillhart, Lea Angst, Hansmartin Spatzier, Murali Srinivasan

Objective

This pilot study assessed the feasibility of using facial thermography to detect intra-oral problems in older adults with cognitive decline and care-resistant behaviors, who are often unable to communicate pain or early symptoms.

Methods

Twenty-three older adults (mean age 73.7 ± 13.2 years) with cognitive decline were enrolled. Thermal images of four facial views were taken using a smartphone-connected thermal camera. Intra-oral examinations were conducted, and the thermographic data were analyzed to extract temperature values in the regions of interest (ROI). Point-biserial correlations and ROC curve analyses were performed to evaluate associations between temperature data and clinical findings, with a significance level of p < 0.05.

Results

Intra-oral issues requiring treatment were found in 12 participants, with six reporting clinical pain. The overall mean temperature in the ROI was 33.5 ± 3.9 °C, and significant temperature differences were found between the body and ROI temperatures. Correlations were observed between clinical problems and various temperature metrics, including the minimum and maximum ROI temperatures (rpb=-0.327, p = 0.002 and rpb=-0.309, p = 0.003). ROC analysis indicated that ROI temperature could predict the presence or absence of clinical problems, with AUC values ranging from 0.651 to 0.796 for different metrics.

Conclusion

Thermographic facial imaging shows significant potential as a non-invasive tool for detecting oral health problems in vulnerable older adults. While promising, further research is essential to enhance image quality, streamline the technique, and incorporate AI for improved diagnostic accuracy and ease of use.

Clinical Significance

This non-invasive, inexpensive technique is easy to perform, independent of patient compliance and, is promising to detect early oral problems in noncommunicative patients.
目的:本初步研究评估了使用面部热像仪检测认知能力下降和护理抵抗行为的老年人口腔内问题的可行性,这些老年人通常无法沟通疼痛或早期症状。方法:纳入23例认知能力下降的老年人(平均年龄73.7±13.2岁)。使用智能手机连接的FLIR热像仪拍摄四张面部图像。进行口腔内检查,分析热成像数据以提取感兴趣区域(ROI)的温度值。采用点双列相关和ROC曲线分析来评估温度数据与临床表现之间的相关性,结果具有显著性水平:12名参与者发现需要治疗的口腔内问题,其中6名报告临床疼痛。ROI的整体平均温度为33.5±3.9°C,身体温度与ROI温度之间存在显著差异。观察到临床问题与各种温度指标之间的相关性,包括最低和最高ROI温度(rpb=-0.327, p=0.002和rpb=-0.309, p=0.003)。ROC分析显示ROI温度可以预测临床问题的存在与否,不同指标的AUC值在0.651 ~ 0.796之间。结论:热成像面部成像作为一种非侵入性的检测老年人口腔健康问题的工具具有重要的潜力。虽然前景光明,但进一步的研究对于提高图像质量,简化技术,并结合人工智能来提高诊断准确性和易用性至关重要。临床意义:这种无创、廉价的技术易于实施,与患者依从性无关,有望检测非交流患者的早期口腔问题。
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引用次数: 0
Dynamic navigation-guided robotic placement of zygomatic implants 动态导航引导下的机器人颧骨植入术
IF 4.8 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.jdent.2024.105463
Mohammed Y. Al-Jarsha , Yufeng Diao , Guodong Zhao , Muhammad A. Imran , Ashraf F. Ayoub , Douglas P. Robertson , Kurt B. Naudi

Objectives

To assess the feasibility and accuracy of a new prototype robotic implant system for the placement of zygomatic implants in edentulous maxillary models.

Methods

The study was carried out on eight plastic models. Cone beam computed tomographs were captured for each model to plan the positions of zygomatic implants. The hand-eye calibration technique was used to register the dynamic navigation system to the robotic spaces. A total of 16 zygomatic implants were placed, equally distributed between the anterior and the posterior parts of the zygoma. The placement of the implants (ZYGAN®, Southern Implants) was carried out using an active six-jointed robotic arm (UR3e, Universal Robots) guided by the dynamic navigation coordinate transformation matrix. The accuracy of the implant placement was assessed using EvaluNav and GeoMagicDesignX® software based on pre- and post-operative CBCT superimposition. Descriptive statistics for the implant deviations and Pearson's correlation analysis of these deviations to force feedback recorded by the robotic arm were conducted.

Results

The 3D deviations at the entry and exit points were 1.80 ± 0.96 mm and 2.80 ± 0.95 mm, respectively. The angular deviation was 1.74 ± 0.92°. The overall registration time was 23.8 ± 7.0 min for each side of the model. Operative time excluding registration was 66.8 ± 8.8 min for each trajectory.
The exit point and angular deviations of the implants were positively correlated with the drilling force perpendicular to the long axis of the handpiece and negatively correlated with the drilling force parallel to the long axis of the handpiece.

Conclusion

The errors of the dynamic navigation-guided robotic placement of zygomatic implants were within the clinically acceptable limits. Further refinements are required to facilitate the clinical application of the tested integrated robotic-dynamic navigation system.

Clinical significance

Robotic placement of zygomatic implants has the potential to produce a highly predictable outcome irrespective of the operator's surgical experience or fatigue. The presented study paves the way for clinical applications.
目的:评估新型机器人种植系统在无牙颌模型中植入颧骨种植体的可行性和准确性:评估在无牙上颌模型中植入颧骨种植体的新型机器人种植系统原型的可行性和准确性:研究在八个塑料模型上进行。对每个模型进行锥形束计算机断层扫描,以规划颧骨种植体的位置。使用手眼校准技术将动态导航系统注册到机器人空间。总共植入了 16 个颧骨植入体,平均分布在颧骨的前部和后部。种植体(ZYGAN®,Southern Implants)的植入是在动态导航坐标变换矩阵的引导下,使用主动六关节机器人手臂(UR3e,Universal Robots)完成的。根据术前和术后的 CBCT 叠加结果,使用 EvaluNav 和 GeoMagicDesignX® 软件对种植体植入的准确性进行了评估。对种植体偏差进行了描述性统计,并对这些偏差与机械臂记录的力反馈进行了皮尔逊相关分析:结果:入口点和出口点的三维偏差分别为 1.80 ± 0.96 毫米和 2.80 ± 0.95 毫米。角度偏差为 1.74 ± 0.92°。模型每侧的整体配准时间为 23.8 ± 7.0 分钟。每条轨迹的手术时间(不包括配准时间)为 66.8 ± 8.8 分钟。种植体的出口点和角度偏差与垂直于手机长轴的钻孔力呈正相关,而与平行于手机长轴的钻孔力呈负相关:结论:动态导航引导机器人植入颧骨种植体的误差在临床可接受范围内。临床意义:临床意义:无论操作者的手术经验或疲劳程度如何,机器人植入颧骨种植体都有可能产生高度可预测的结果。本研究为临床应用铺平了道路。
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引用次数: 0
Preventive potential of arginine incorporated in fancy waters for erosive tooth wear 精氨酸的预防潜力纳入花式水侵蚀牙齿磨损。
IF 4.8 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.jdent.2024.105500
Mohammed Nadeem Bijle , Dalya Sharaf , Moussa Aneess Mohamed Bahdar , Umer Daood , Cynthia Yiu

Objective(s)

The aim of the study was to examine the potential of arginine (Arg)-enriched fancy waters in preventing erosive tooth wear.

Methods

L-arginine (2 % w/v.) was added to five commercial fancy waters: Oasis-Lemon, Oasis-Lemon Mint, Perrier-Lemon, Perrier-Grapefruit, Pellegrino-Lemon; and deionized water served as a negative control. The pH, buffer capacity of added Arg, and F concentrations were measured. Tooth specimens were prepared and baseline volumetric assessment (T0) was conducted using micro-CT. Subsequently, the specimens were immersed in fancy waters for 72 h, kept in an incubator (37 ℃) and solutions were changed every 24 h. After the experimental cycle (T1), 3D volumetric analysis was performed, and 3D structural images were reconstructed for qualitative assessment.

Results

The pH and F concentrations of fancy waters with Arg were significantly higher than the control (p < 0.001). The buffer capacity of added Arg with Perrier-Grapefruit was significantly higher than Oasis-Lemon, Oasis-Lemon Mint & Pellegrino-Lemon (p < 0.05), except for Perrier-Lemon (p > 0.05). At T1, the specimen volume in Oasis-Lemon Mint (+/− Arg) and Pellegrino-Lemon (control) was significantly lower than T0 (p < 0.05). At T1, the specimen volume of Oasis-Lemon Mint and Pellegrino-Lemon (control) was significantly lower than Arg-containing fancy waters (p < 0.05). Surface contrast indicating wear was evident from T0 to T1 in specimens from the Oasis-Lemon Mint (+/− Arg) and Pellegrino-Lemon (− Arg).

Conclusion

Incorporating Arg in fancy waters reduces the potential of erosive tooth wear associated with these beverages.

Clinical significance

Consuming fancy water beverages (flavoured sparkling/carbonated) can lead to erosive tooth wear in young people. Incorporating Arg in fancy water beverages can prevent the erosive wear potential of these beverages while alleviating the burden of oral care on individuals at risk to erosive wear.
目的:本研究的目的是研究富含精氨酸(Arg)的花式水在预防牙齿侵蚀磨损方面的潜力。方法:将l -精氨酸(2% w/v)加入5种商业花式水中:Oasis-Lemon、Oasis-Lemon Mint、Perrier-Lemon、perrier -葡萄柚、Pellegrino-Lemon;去离子水作为阴性对照。测定了pH、添加精氨酸的缓冲容量和F-浓度。制备牙齿标本,并使用micro-CT进行基线体积评估(T0)。随后,将标本在泡水中浸泡72 h,在37℃的培养箱中保存,每24 h更换一次溶液。实验周期(T1)结束后,进行三维体积分析,并重建三维结构图像进行定性评价。结果:添加精氨酸的花式水的pH和F-浓度显著高于对照组(p0.05)。在T1时,绿洲-柠檬薄荷(+/-精氨酸)和培莱格诺-柠檬(对照)中的标本体积显著低于T0 (p)。结论:在花式水中加入精氨酸可以减少与这些饮料相关的牙齿侵蚀磨损的可能性。临床意义:(44个字):饮用花哨的水饮料(调味气泡/碳酸饮料)会导致年轻人牙齿腐蚀磨损。在高档水饮料中加入精氨酸可以防止这些饮料的侵蚀磨损潜力,同时减轻有侵蚀磨损风险的个人的口腔护理负担。
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引用次数: 0
Clinical performance of an ormocer-based single-shade resin composite for the restoration of non-carious cervical lesions: 18-month randomized clinical trial 基于ormocer的单色树脂复合材料修复宫颈非龋齿病变的临床性能:18个月随机临床试验
IF 4.8 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.jdent.2024.105519
Thalita de Paris Matos , Kaliane Rodrigues da Cruz , Michael Willian Favoreto , Andrea dos Santos de Castro , Mylena de Abreu Cardoso , Flares Baratto-Filho , Cristiano Miranda de Araujo , Mauricio Aguirre-Balseca , Alessandra Reis , Alessandro D. Loguercio

Objective

This double-blind, split-mouth, randomized equivalence clinical trial aimed to evaluate the 18-month clinical performance of an ormocer-based single-shade resin composite compared with an ormocer-based multi-shade resin composite in non-carious cervical lesions (NCCLs).

Methods

One hundred and twenty restorations were performed on NCCLs with two restorative materials (n = 60): Admira Fusion X-tra resin composite (ormocer-based single-shade), and Admira Fusion resin composite (ormocer-based multi-shade). After rubber dam isolation, a universal adhesive was applied in the selective enamel etching strategy. For both groups, restorations were inserted incrementally and light-cured. The restorations were clinically evaluated at 6, 12, and 18 months according to the updated FDI (World Dental Federation) criteria. Statistical analysis was performed using Friedman repeated measures ANOVA by rank and Mann-Whitney test for pairwise significance (α = 0.05).

Results

All restorations were evaluated after 18 months, and nine restorations were lost. Fracture of the material and retention rates (95 % confidence interval [CI]) were 93 % (84–97 CI) for the ormocer-based single-shade and 91 % (82–96 CI) for the ormocer-based multi-shade, with no statistical differences between them (p > 0.05). The absolute risk (95 % CI) was 0.8 (0.2 to 3.1).

Conclusions

The updated FDI evaluation criteria showed equivalent results for ormocer-based single-shade and ormocer-based multi-shade after 18 months.

Clinical significance

Using an ormocer-based single-shade resin composite in NCCLs is advisable due to its convenience, ease of application, and lower cost compared to ormocer-based multi-shade composites without compromising clinical performance.
目的:这项双盲、裂口、随机等效临床试验旨在评估基于ormocer的单色树脂复合材料与基于ormocer的多色树脂复合材料在非龋齿宫颈病变(ncls)中的18个月临床表现。方法:采用两种修复材料(n = 60):Admira Fusion X-tra树脂复合材料(ormoser基单色)和Admira Fusion树脂复合材料(ormoser基多色)对120例ncls进行修复。橡胶坝隔离后,采用通用胶粘剂进行选择性牙釉质蚀刻。对于两组,修复体都是增量插入和光固化的。根据最新的FDI(世界牙科联合会)标准,在6、12和18个月时对修复体进行临床评估。统计学分析采用Friedman重复测量方差分析,采用秩和Mann-Whitney检验两两显著性(α = 0.05)。结果:所有修复体在18个月后进行评估,9个修复体丢失。单侧ormoer的材料断裂率和保留率(95%置信区间[CI])为93% (84-97 CI),多侧ormoer的材料断裂率和保留率为91% (82-96 CI),两者之间无统计学差异(p < 0.05)。绝对风险(95% CI)为0.8(0.2 ~ 3.1)。结论:更新后的FDI评价标准在18个月后显示基于ormocer的单色和基于ormocer的多色结果相当。临床意义:与ormocer基多色复合材料相比,使用ormocer基单色树脂复合材料在不影响临床性能的情况下,方便,易于应用,成本更低,因此在ncls中使用ormocer基单色树脂复合材料是可取的。
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引用次数: 0
A double-blind randomized crossover trial comparing the esthetic outcomes of CAD-CAM provisional restorations fabricated using CBCT and IOS acquisition methods 一项双盲随机交叉试验,比较使用CBCT和IOS获取方法制作CAD-CAM临时修复体的美学结果。
IF 4.8 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.jdent.2024.105545
Amrutha Shenoy , Subhabrata Maiti , Deepak Nallaswamy , Murali Srinivasan

Objectives

This double-blind randomised crossover trial aimed to compare the aesthetic outcomes of CAD-CAM manufactured provisional restorations created using cone beam computed tomography (CBCT) and intraoral scanners (IOS) acquisition methods.

Methods

Twelve participants (mean-age: 38 ± 5 years) requiring full mouth rehabilitation were included in this crossover trial. Two sets of identical CAD-CAM provisional restorations, differing only in the method of data acquisition (A: CBCT, B: IOS), were fabricated. Restorations were cemented for two weeks, with washout period between interventions. Esthetic evaluations were conducted using clinician and patient-reported outcome questionnaires. Both parametric and non-parametric tests were used to account for data variability: Mann-Whitney U test compared pink esthetic score (PES), white esthetic score (WES), and modified US Public Health Service (USPHS) score. An unpaired t-test compared Oral Health Impact Profile- Aesthetic Questionnaire (OHIP-Aes) scores and Orofacial Esthetic scores.

Results

Clinician-reported outcomes showed significantly better esthetic scores for provisional restorations fabricated using CBCT compared to IOS. CBCT scored higher in Pink Esthetic Score (PES) [Mean rank: CBCT = 16.00, IOS = 9.00; P = 0.012] and White Esthetic Score (WES) [Mean rank: CBCT = 17.25, IOS = 7.75; P < 0.001]. No significant differences were observed for Modified USPHS scores across groups [Mean rank: CBCT = 11.38, IOS = 13.63; P = 0.221]. Patient-reported outcomes indicated no significant differences between groups in OHIP-Aes scores [CBCT = 1.25 ± 1.76, IOS = 1.58 ± 1.62; P = 0.635] or Orofacial Esthetic Index (OFEI) scores [CBCT = 65.75 ± 1.54, IOS = 65.50 ± 1.62; P = 0.703].

Conclusion

Both CBCT and IOS acquisition techniques provide aesthetically satisfactory CAD-CAM provisional restorations. CBCT demonstrated significantly higher clinician-reported esthetic outcomes for both pink and white esthetic scores. While patient satisfaction was similar for both methods, CBCT offers practical advantages, including the elimination of separate diagnostic appointments, making it a preferred choice for enhanced esthetic outcomes in CAD-CAM provisional restorations.

Clinical implications

CBCT acquisition methods yield significantly better clinician-reported esthetic outcomes for CAD-CAM provisional restorations compared to IOS. Additionally, CBCT eliminates the need for separate diagnostic appointments, reducing treatment time and number of visits, while both methods provide similar satisfactory patient-reported outcomes.

Clinical trial registration number

Approval number: CTRI/2023/03/050410.
目的:本双盲随机交叉试验旨在比较使用锥形束计算机断层扫描(CBCT)和口内扫描仪(IOS)获取方法创建的CAD-CAM制造的临时修复体的美学结果。方法:交叉试验纳入12例需要全口康复的患者(平均年龄:38±5岁)。制作两组相同的CAD-CAM临时修复体,仅在数据获取方法上不同(A: CBCT, B: IOS)。修复体固定两周,干预之间有洗脱期。美学评估采用临床医生和患者报告的结果问卷进行。参数检验和非参数检验均用于解释数据变异性:Mann-Whitney U检验比较了粉色审美评分(PES)、白色审美评分(WES)和修改后的美国公共卫生服务(USPHS)评分。非配对t检验比较口腔健康影响概况-美学问卷(ohip - ae)得分和口腔面部美学得分。结果:临床报告的结果显示,与IOS相比,使用CBCT制作的临时修复体的美学评分显着提高。CBCT在粉红审美评分(PES)中得分较高[平均排名:CBCT=16.00, IOS=9.00;P=0.012]和White aesthetic Score (WES)[平均排名:CBCT=17.25, IOS=7.75;结论:CBCT和IOS采集技术均可提供美观满意的CAD-CAM临时修复体。CBCT显示,临床报告的粉红色和白色美学评分结果显著较高。虽然两种方法的患者满意度相似,但CBCT具有实际优势,包括消除单独的诊断预约,使其成为CAD-CAM临时修复中增强美学结果的首选。
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引用次数: 0
期刊
Journal of dentistry
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