Journal of dentistry最新文献

{"title":"CircFak promotes mechanical force-induced osteogenesis via FAK/AKT phosphorylation","authors":"Zhihui Wen ,&nbsp;Fan Wu ,&nbsp;Juanyi Shi ,&nbsp;Huilin Cheng ,&nbsp;Shule Xie ,&nbsp;Defeng Liang ,&nbsp;Jinsong Li ,&nbsp;Yingjuan Lu","doi":"10.1016/j.jdent.2025.105602","DOIUrl":"10.1016/j.jdent.2025.105602","url":null,"abstract":"<div><h3>Objectives</h3><div>Orthodontic treatment is widely applied for addressing orofacial skeletal deformities, with the remodeling of the alveolar bone under mechanical force being the key factor. FAK is essential for cellular response to mechanical force. However, the function of <em>circFak</em> has never been reported. In this study, the microarrays showed that <em>circFak</em> may affect osteogenesis under mechanical force. We aimed to verify the effect of <em>circFak</em> in force-related bone remodeling and investigate the underlying mechanisms.</div></div><div><h3>Methods</h3><div>Arraystar microarrays were used to identify differentially expressed circRNAs and microRNAs in response to mechanical stress. The subcellular distribution of <em>circFak</em> was analyzed via RT‒qPCR and FISH. ALP and ARS staining assays were performed to investigate the effects of <em>circFak</em> on osteogenesis. RNA sequencing, bioinformatics analysis, dual-luciferase reporter assays, and RNA immunoprecipitation were accomplished to discover the molecular mechanisms of <em>circFak. AAV-sh-circFak</em> mouse models with tooth movements were established. The role of <em>circFak</em> under mechanical force in vivo was assessed via immunofluorescence and micro-CT analyses.</div></div><div><h3>Results</h3><div><em>CircFak</em> expression was significantly upregulated under mechanical force. Osteogenic capacity of osteoblasts was positively correlated with the level of <em>circFak. CircFak</em> promoted mechanical force-induced osteogenesis through <em>miR-425–5p</em>/<em>Ccn3</em> pathway, and further stimulated the phosphorylation of its parental sourced protein FAK. Our murine models showed that AAV-mediated <em>circFak</em> silencing suppressed osteogenesis.</div></div><div><h3>Conclusion</h3><div><em>CircFak</em> could obviously promote osteogenesis under mechanical force and may possess ability to become a novel biomarker for prognosis of orthodontic treatments.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"154 ","pages":"Article 105602"},"PeriodicalIF":4.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atraumatic restorative treatment induces transient changes in salivary total protein and redox biomarkers in children with caries: A non-randomized clinical study","authors":"Adrielle Ouchi Lopes ,&nbsp;Rayara Nogueira de Freitas ,&nbsp;Gabriela Alice Fiais ,&nbsp;Haylla de Faria Horta ,&nbsp;Alanna Ramalho Mateus ,&nbsp;Heitor Ceolin Araujo ,&nbsp;Alessandra Marcondes Aranega ,&nbsp;Beatriz Díaz-Fabregat ,&nbsp;Antonio Hernandes Chaves-Neto ,&nbsp;Cristina Antoniali","doi":"10.1016/j.jdent.2024.105521","DOIUrl":"10.1016/j.jdent.2024.105521","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to evaluate if dental atraumatic restorative treatment (ART) impacts salivary total protein and redox biomarkers in children with caries.</div></div><div><h3>Methods</h3><div>The study included 30 children (aged 4 to 6 years) with caries on posterior deciduous teeth, classified by ICCMS, attending a basic education school. Participants were divided into enamel (<em>n</em> = 15) and dentin (<em>n</em> = 15) lesion groups. Unstimulated saliva samples were collected before (B), immediately after (A), and seven days after (A7) ART. Analyses included total protein concentration, lipid peroxidation (TBARS), total antioxidant capacity (TAC), and uric acid (UA). The results obtained at different time points (B, A, A7) were compared between children with caries and between those with enamel or dentin lesions using a paired repeated-measures ANOVA, followed by Tukey's post-hoc test (<em>p</em> &lt; 0.05).</div></div><div><h3>Results</h3><div>ART caused significant decreases in total protein concentration (<em>p</em> = 0.0146), which rebounded by the 7th day. TBARS levels increased (<em>p</em> = 0.0215) immediately after ART and remained unchanged until the 7th day. TAC (<em>p</em> = 0.0032) and UA (<em>p</em> = 0.0006) levels decreased in the saliva of children 7 days after ART. These changes were significant only in children with dentin lesions, not enamel lesions.</div></div><div><h3>Conclusion</h3><div>ART temporarily alters salivary protein levels and redox biomarkers in children with caries, returning to baseline after 7 days. These findings highlight the importance of complementing restorative treatments with dietary advice and oral hygiene to ensure comprehensive caries management.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"153 ","pages":"Article 105521"},"PeriodicalIF":4.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientific trends in clinical trials on tooth bleaching: A bibliometric and altmetric review","authors":"Aurélio de Oliveira Rocha ,&nbsp;Michael Willian Favoreto ,&nbsp;Lucas Menezes dos Anjos ,&nbsp;Bruno Henriques ,&nbsp;Alessandro D. Loguercio ,&nbsp;Alessandra Reis ,&nbsp;Mariane Cardoso","doi":"10.1016/j.jdent.2024.105550","DOIUrl":"10.1016/j.jdent.2024.105550","url":null,"abstract":"<div><h3>Objectives</h3><div>The aim of this study was to analyze the characteristics and trends of publications in clinical trials on tooth bleaching through a bibliometric and altmetric analysis.</div></div><div><h3>Methods</h3><div>A search was conducted in September 2024 on Web of Science Core Collection (WoS-CC) and Scopus. Two researchers selected articles and extracted key study characteristics. VOSviewer was used to generate bibliometric networks. Dimensions was consulted to measure altmetric data.</div></div><div><h3>Results</h3><div>416 studies were included, published between 1990 and 2024. The most cited study obtained 164 citations on WoS-CC and 201 on Scopus. The studies predominantly investigated bleaching efficacy (<em>n</em> = 232), often employing double-blind designs (<em>n</em> = 146), conducted in adults (<em>n</em> = 403), randomized (<em>n</em> = 307), and mainly using hydrogen peroxide (<em>n</em> = 200) for at-home vital dental bleaching (<em>n</em> = 199). The majority of the articles were published by Brazilian authors (<em>n</em> = 165), with Loguercio AD (<em>n</em> = 70) and Reis A (<em>n</em> = 56) being the most frequent authors. The manufacturer FGM led with the highest number of investigated products (<em>n</em> = 153), particularly highlighting Whiteness HP Maxx 35 % (<em>n</em> = 40). VOSviewer revealed significant collaborations among authors and keywords. According to Dimensions, users of Mendeley and news outlets have shown great interest in whitening clinical trials.</div></div><div><h3>Conclusion</h3><div>This study highlighted a growing trend in clinical trials on tooth bleaching over 30 years, with a strong predominance of studies conducted in Brazil that primarily investigated bleaching efficacy through double-blind designs in adults using hydrogen peroxide.</div></div><div><h3>Clinical significance</h3><div>Clinical trials on tooth bleaching represent one of the highest levels of scientific evidence guiding clinical practice, thus requiring thorough evaluation.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"153 ","pages":"Article 105550"},"PeriodicalIF":4.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of detection methods for secondary caries around direct restorations: A systematic review and meta-analysis","authors":"Jason Chi-Kit Ku ,&nbsp;Walter Yu-Hang Lam ,&nbsp;Kar Yan Li ,&nbsp;Richard Tai-Chiu Hsung ,&nbsp;Chun-Hung Chu ,&nbsp;Ollie Yiru Yu","doi":"10.1016/j.jdent.2024.105541","DOIUrl":"10.1016/j.jdent.2024.105541","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate and compare the accuracy of detection methods for the diagnosis of secondary caries around direct restorations in posterior teeth.</div></div><div><h3>Data</h3><div>Accuracy parameters including sensitivity, specificity, diagnostic odds ratio (DOR), area under curve (AUC), and partial AUC (pAUC) are generated from studies assessing the accuracy of detection methods for secondary caries.</div></div><div><h3>Sources</h3><div>Publications from PubMed, Web of Science, Scopus, Medline, EMBASE and Cochrane Library databases.</div></div><div><h3>Study selection/results</h3><div>This review included 25 studies evaluating visual examination (V(laboratory); <em>n</em> = 9 &amp; V(clinical); <em>n</em> = 2), tactile examination (T; <em>n</em> = 3), intra-oral radiography (IR; <em>n</em> = 14), cone-beam computed tomography (CBCT; <em>n</em> = 4), quantitative light-induced fluorescence (QLF; <em>n</em> = 4), laser fluorescence (LF; <em>n</em> = 8) and digital imaging fiber-optic transillumination (DIFOTI; <em>n</em> = 1). The pooled sensitivity [95 % Confidence Interval, CI] and specificity [95 % CI] of detection methods for secondary caries were 0.60[0.45–0.73] and 0.67[0.53–0.78] for V(laboratory); 0.82[0.23–0.99] and 0.77[0.15–0.98] for V(clinical); 0.31[0.25–0.39] and 0.95[0.78–0.99] for T; 0.59[0.52–0.66] and 0.82[0.75–0.88] for IR; 0.61[0.48–0.73] and 0.82[0.64–0.92] for CBCT; 0.71[0.64–0.78] and 0.51[0.40–0.62] for QLF; 0.57[0.43–0.71] and 0.81[0.76–0.85] for LF; and 0.63[0.47–0.76] and 0.95[0.90–0.98] for DIFOTI. DOR values [95 % CI] of the secondary caries detection methods were V(laboratory)-2.88[2.18–3.80]; V(clinical)-16.66[3.84–72.28]; T-6.36[1.12–36.28]; IR-6.55[3.44–12.46]; CBCT-6.18[1.42–26.91]; QLF-2.25[1.39–3.63]; LF-4.86[2.40–9.82]; and DIFOTI-30.00[11.94–75.36], respectively. Respective AUC (pAUC) were V-0.645(0.535); T-0.379(0.315); IR-0.767(0.693); CBCT-0.887(0.820); QLF-0.581(0.633) and LF-0.828(0.590). AUC values were not available for DIFOTI and V(clinical).</div></div><div><h3>Conclusions</h3><div>Among the seven types of detection method for secondary caries diagnosis, none of the detection methods demonstrate satisfactory accuracy in detecting secondary caries around direct restorations in posterior teeth.</div></div><div><h3>Clinical significance</h3><div>This systematic review provides insights for the clinician and researcher in selecting the clinical detection method for secondary caries diagnosis and facilitates clinical decision making.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"153 ","pages":"Article 105541"},"PeriodicalIF":4.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A personalized periodontitis risk based on nonimage electronic dental records by machine learning","authors":"Laura Swinckels ,&nbsp;Ander de Keijzer ,&nbsp;Bruno G. Loos ,&nbsp;Reuben Joseph Applegate ,&nbsp;Krishna Kumar Kookal ,&nbsp;Elsbeth Kalenderian ,&nbsp;Harmen Bijwaard ,&nbsp;Josef Bruers","doi":"10.1016/j.jdent.2024.105469","DOIUrl":"10.1016/j.jdent.2024.105469","url":null,"abstract":"<div><div><strong><em>Objective</em></strong>: This study aimed to develop a machine-learning (ML) model to predict the risk for Periodontal Disease (PD) based on nonimage electronic dental records (EDRs).</div><div><strong><em>Methods</em></strong>: By using EDRs collected in the BigMouth repository, dental patients from the US were included. Patients were labeled as cases or controls, based on PD diagnosis, treatment and pocketing. By learning from their data, a model was trained. The ability of the developed model to predict PD was evaluated by the accuracy, sensitivity, specificity and area under the curve (AUROC) and the most important features were determined. The best-performing model was applied to the validation set.</div><div><strong><em>Results</em></strong>: The final study population included 43,331 participants. Based on the development set, the Random Forest model performed with high sensitivity (81 %) and had an excellent AUROC (94 %), compared to four other ML and deep learning techniques. The most important predictors were bleeding proportion, age, the number of visits, prior preventive treatment, smoking and drugs usage. When the model was applied to the validation set, the model could detect almost all cases (91 %), but overestimated controls (specificity=0.54). When EDRs were retrieved 3 years before the PD diagnosis, the predictions for PD were still sensitive (89 %).</div><div><strong><em>Conclusion</em></strong>: Based on consistent and complete EDR, ML has an excellent ability to assist with the early detection and prevention of PD cases. Further research is required to follow-up high-risk controls and improve the model's internal and external validation. Improved EDR documentation is an important first step.</div><div><strong><em>Clinical significance</em></strong>: If such ML models become clinically applied, clinicians can be assisted with personalized risk predictions based on the individual. If the key riskcontributing factors for the individual are revealed/provided, ML can suggest targeted prevention interventions. These advancements can contribute to a reduced workload, sustainable EDRs, data-based dental care, and, ultimately, improved patient outcomes.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"153 ","pages":"Article 105469"},"PeriodicalIF":4.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival of dental implants placed in a postgraduate educational setting: a retrospective cohort study","authors":"Vito Carlo Alberto Caponio ,&nbsp;Ajay Sharma ,&nbsp;Gennaro Musella ,&nbsp;Vittoria Perrotti ,&nbsp;Alessandro Quaranta","doi":"10.1016/j.jdent.2024.105531","DOIUrl":"10.1016/j.jdent.2024.105531","url":null,"abstract":"<div><h3>Introduction</h3><div>Dental implant treatment can still fail due to various factors. The aim of this retrospective cohort study was to assess the influence of operator experience in a postgraduate educational setting, as well as patient, implant, and surgical risk factors on the incidence of the dental implant failure.</div></div><div><h3>Methods</h3><div>The dental records of 1049 implants with a mean follow-up of 794.70 days were analysed. Variables included operator experience (year of specialty study) and clinic-pathological patients’ related variables. Clinic-pathological associations were explored and a Cox regression model accounted for implant survival factors.</div></div><div><h3>Results</h3><div>Multivariate analysis revealed that a history of periodontitis and smoking were the only factors with independent prognostic value, with hazard ratios of 2.0 (95 % CI: 1.0–4.0, <em>p</em> = 0.048) and 1.9 (95 % CI: 1.0–3.6, <em>p</em> = 0.039) respectively. Conversely, despite implant treatment delivered by early career students had a higher failure rate (5.6 %) compared to advanced career students (3.7 %), this difference was statistically significant only in the univariate analysis.</div></div><div><h3>Conclusion</h3><div>Periodontitis and smoking are independent prognostic variables, with career level potentially biasing complex case allocation to advanced students. Targeted educational interventions, including virtual reality and artificial intelligence, should be emphasized in student training. University-based implant trials must consider operator career stage.</div></div><div><h3>Clinical significance</h3><div>The study underscores the importance of operator experience in dental implant success. It highlights that while clinical experience influences outcomes, factors like a history of periodontitis and smoking are independent predictors of implant failure. These findings emphasize the need for targeted educational interventions to improve clinical training and patient outcomes.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"153 ","pages":"Article 105531"},"PeriodicalIF":4.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142836853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effectiveness of Platelet Rich Fibrin in Alveolar Ridge Reconstructive or Guided Bone Regenerative Procedures: A Systematic Review and Meta-Analysis","authors":"M. Arora ,&nbsp;N. McAulay ,&nbsp;A. Farag ,&nbsp;ZS. Natto ,&nbsp;J. Lu ,&nbsp;R. Albuquerque ,&nbsp;E M-C. Lu","doi":"10.1016/j.jdent.2024.105548","DOIUrl":"10.1016/j.jdent.2024.105548","url":null,"abstract":"<div><h3>Introduction and Objectives</h3><div>Clinical studies have shown favorable outcomes following use of platelet rich fibrin (PRF), either alone or in conjunction with biomaterials for alveolar ridge reconstruction (ARR) or guided bone regeneration (GBR) . While PRF application accelerates wound healing and reduces postoperative discomfort, its effects on the alveolar bone gain, as part of ARR or GBR is less clear. Therefore, this study aims to investigate the clinical effectiveness of PRF when used in ARR or GBR, as well as postoperative discomfort following these procedures.</div></div><div><h3>Sources</h3><div>A systematic search using the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) method was performed to include database searches from MEDLINE (OVID interface, 1946 onwards), EMBASE (OVID interface, 1974 onwards) and Global Health (OVID interface, 1973 onwards).</div></div><div><h3>Data</h3><div>Of the 74 studies initially identified, 7 studies were included for the systematic review, including 6 randomized controlled trials (RCTs) and 1 cohort study. The meta-analysis showed that the incorporation of PRF as part of ARR or GBR resulted in an increase in horizontal ridge width, a reduction in the rate of resorption increase, while postoperative discomfort was the same or slightly improved. The risk of bias quality was low for only 1 out of the 6 RCTs and the Newcastle Ottawa scale assessment showed that cohort study was of high quality.</div></div><div><h3>Conclusion</h3><div>PRF application in ARR or GBR is associated with increased horizonal alveolar ridge width and reduce rate of graft resorption. However, the findings related to both outcome measures were based on a limited number of studies.</div></div><div><h3>Clinical significance</h3><div>PRF application can be effectively used as part of ARR or GBR to increase the horizontal ridge width and reduce the rate of graft resorption</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"153 ","pages":"Article 105548"},"PeriodicalIF":4.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical evaluation of the accuracy of two face scanners with different scanning technologies","authors":"Murali Srinivasan ,&nbsp;Claudio Rodrigues Leles ,&nbsp;Florentin Berisha ,&nbsp;Innocenzo Bronzino ,&nbsp;Yasmin Milhomens ,&nbsp;Sung-Jin Kim ,&nbsp;Koungjin Park ,&nbsp;Jae-Hyun Lee","doi":"10.1016/j.jdent.2024.105553","DOIUrl":"10.1016/j.jdent.2024.105553","url":null,"abstract":"<div><h3>Objectives</h3><div>This study compared the clinical accuracy of two different stationary face scanners, employing progressive capture and multi-view simultaneous capture scanning technologies.</div></div><div><h3>Methods</h3><div>Forty dentate volunteers participated in the study. Soft tissue landmarks were marked with a pen on the participants' faces to measure the distances between them. Clinical measurements were manually obtained using a digital vernier caliper by two independent examiners. The participants were then scanned using one of two stationary face scanners: Obiscanner (Fifthingenium), which employs progressive capture technology requiring the subject's head to rotate during image acquisition, or RAYFace (RAY), which utilizes multiple cameras to simultaneously capture a complete 3D image. The scans were imported into mesh-processing software, and digital measurements were taken by the same examiners. Data analysis included pairwise comparison tests and the calculation of the intra-class correlation coefficient (ICC; α = 0.05).</div></div><div><h3>Results</h3><div>Digital measurements were significantly longer than clinical measurements across all measured distances (<em>p</em> &lt; 0.001). Comparisons between the scanners revealed that vertical measurements using RAYface exhibited greater percentage differences compared to those using Obiscanner (<em>p</em> &lt; 0.05), while horizontal measurements were more variable with Obiscanner than those obtained using RAYface (<em>p</em> &lt; 0.05). Intra-examiner differences were significant for both methods (<em>p</em> &lt; 0.001), although inter-examiner differences were only significant for clinical measurements (<em>p</em> &lt; 0.001), not for digital measurements (<em>p</em> &gt; 0.05). Inter-examiner reliability for digital measurements was high (ICC≥0.99).</div></div><div><h3>Conclusions</h3><div>Significant differences were observed in the accuracy of the two stationary face scanners using progressive capture and multi-view simultaneous capture scanning technologies, with each device demonstrating specific strengths and limitations.</div></div><div><h3>Clinical Significance</h3><div>Although face scanners offer relatively high accuracy and consistency, particularly across different acquisition technologies, careful consideration of their performance characteristics is essential for optimizing accuracy in facial measurements.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"153 ","pages":"Article 105553"},"PeriodicalIF":4.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142914991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vivo comparison of resin infiltration outcomes under different light conditions: A randomized controlled clinical trial","authors":"Omar Marouane ,&nbsp;David John Manton ,&nbsp;Marcus Cebula ,&nbsp;Falk Schwendicke ,&nbsp;Susanne Effenberger","doi":"10.1016/j.jdent.2024.105554","DOIUrl":"10.1016/j.jdent.2024.105554","url":null,"abstract":"<div><h3>Objective</h3><div>Success of resin infiltration for the masking of MIH-lesions remains difficult to predict, prompting suggestions to adjust the treatment protocol. This exploratory in vivo study aims to evaluate whether monitoring the resin infiltration process using transmitted light, compared to ambient light, enables a better estimation of when the infiltration process is completed, and to assess how the treatment success, i.e. masking effect and infiltration proportion, is influenced accordingly.</div></div><div><h3>Methods</h3><div>15 patients with 19 MIH-lesions, diagnosed according to EAPD diagnostic criteria, were enrolled. MIH-lesions were randomly assigned to two treatment groups. In one group resin infiltration progression was monitored under transmitted light, whereas in the second group ambient light was used, representing the standard procedure. Pictures were taken before infiltration and when progression became evident until infiltration was judged to be completed. Infiltration proportion and color difference between the opacity and surrounding sound enamel were calculated and analyzed using the independent-sample <em>t</em>-test with a level of significance of <em>p</em> &lt; 0.05.</div></div><div><h3>Results</h3><div>Compared to the ambient light group, the transmitted light group showed a significantly higher infiltration time (17.7 ± 8.2 min vs. 9.3 ± 1.6 min); a significantly higher mean infiltration proportion (97.6 ± 2.8% vs. 83.9 ± 9.7%) and a significantly better masking effect (i.e. lower mean color difference (∆E) between effected and sound enamel: 4.5 ± 2.4 vs. 7.5 ± 3.3).</div></div><div><h3>Conclusion</h3><div>Transillumination-guided resin infiltration required prolonged infiltration time but led to an increased infiltration proportion and improved masking effects.</div></div><div><h3>Clinical significance</h3><div>Transillumination guided resin infiltration enables a more accurate judgement as to when the infiltration process has been completed, which leads, through extension of the infiltration time, to a significantly higher mean infiltration proportion and provides favorable esthetic outcomes.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"153 ","pages":"Article 105554"},"PeriodicalIF":4.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Key factors for a national dental implant registry","authors":"Trine Lise Lundekvam Berge ,&nbsp;Gunvor Bentung Lygre ,&nbsp;Bjørn Kubon ,&nbsp;Stein Atle Lie","doi":"10.1016/j.jdent.2025.105603","DOIUrl":"10.1016/j.jdent.2025.105603","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to identify essential factors for establishing a national dental implant registry.</div></div><div><h3>Methods</h3><div>Following a literature review to identify existing national dental implant registries, discussions were carried out with Norwegian medical registry stakeholders. To evaluate methods for collecting data, a pilot study, performing prospective registration of dental implants inserted or removed in five dental clinics during a period of two years, was conducted.</div></div><div><h3>Results</h3><div>Few national dental implant registries were identified. In the pilot study, 1,326 dental implants placed in 781 patients were registered. One year after insertion, the estimated failure was 2.9 % (95% CI: 2.0–4.1). Based on collaboration with clinicians, the dataset was revised to enhance the accuracy of details of implant placement. Registry procedures were structured for easy integration with electronic patient records, focusing on patient details, planned prosthetic restoration, surgical procedures, and dates for implant placement or loss</div></div><div><h3>Conclusions</h3><div>When establishing a national dental implant register, interaction with clinicians, efficient data collection, regulatory compliance, and resources to maintain the registry are essential. Prioritizing relevant and adequate variables based on a \"need-to-know\" principle is crucial.</div></div><div><h3>Clinical relevance</h3><div>A national dental implant registry could enable generalization of findings and provide comprehensive success rates across diverse patient groups and clinical settings. This study contributes insights on establishing a national dental implant registry to improve the quality of implants used in clinical practice</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"154 ","pages":"Article 105603"},"PeriodicalIF":4.8,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}