首页 > 最新文献

Journal of dentistry最新文献

英文 中文
Comparative analysis of five AI platforms for mandibular canal segmentation on CBCT images 五种人工智能平台对CBCT下颌管分割的比较分析。
IF 5.5 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-07 DOI: 10.1016/j.jdent.2026.106345
Sohaib Shujaat , Razan Alotaibi , Amal Aldakhil , Bassam Al Alola , Wael Abolemaaty , Paramjit Khinda , Safa Saeed , Randa Ibrahim , Ali Anwar Aboalela , Kaan Orhan , Nermin Morgan

Objectives

Accurate mandibular canal (MC) identification on cone-beam computed tomography (CBCT) is vital to prevent inferior alveolar nerve injury during oral and maxillofacial procedures. Manual segmentation is time-consuming and operator-dependent, while artificial intelligence (AI) offers automated, reproducible alternatives. This study compared the accuracy of automated MC segmentation across five AI platforms using standardized quantitative and qualitative evaluations.

Methods

A total of 120 anonymized CBCT scans (240 MCs) were analyzed using five fully automated AI-based segmentation platforms: Atomica (Atomica AI, USA), BlueSkyPlan (Blue Sky Bio, USA), Craniocatch (Craniocatch, Türkiye), 3D Slicer (open-source, USA), and Relu Creator (Relu BV, Belgium). Expert-annotated models served as reference. Accuracy was quantified as unsigned mean surface deviation and categorized as optimal (<0.5 mm), acceptable (0.5–2.0 mm), or unacceptable (>2.0 mm). Qualitative evaluation employed a five-point anatomical fidelity scale. Segment-wise, laterality, and scanner-wise effects were also assessed.

Results

Significant performance differences were observed among platforms (p < 0.001). Relu Creator and 3D Slicer achieved the highest overall accuracy (≈0.5 mm) with no >2.0 mm deviations in the complete-canal analysis. Craniocatch showed moderate accuracy, while Atomica and BlueSkyPlan exhibited greater variability and more deviations > 2.0 mm. Qualitative scores reflected similar trends. Regionally, middle canal segments showed the best accuracy, with higher deviations near the mandibular and mental foramina. Scanner- and side-related effects were statistically significant but clinically negligible.

Conclusion

AI-based MC segmentation accuracy varies across platforms. Relu Creator and 3D Slicer achieved near-expert performance suitable for clinical use, while others require expert verification. Independent benchmarking and multi-scanner validation are essential for safe implementation.

Clinical significance

This study provides evidence-based guidance on the accuracy of AI tools for automated MC segmentation, supporting safer surgical planning by identifying which AI-generated outputs can be trusted and where expert verification remains essential to prevent nerve injury.
目的:在口腔颌面外科手术中,通过锥形束计算机断层扫描(CBCT)准确识别下颌管(MC)对预防下牙槽神经损伤至关重要。人工分割耗时且依赖于操作人员,而人工智能(AI)提供了自动化、可重复的替代方案。本研究通过标准化的定量和定性评估,比较了五个人工智能平台上自动MC分割的准确性。方法:使用Atomica (Atomica AI,美国)、BlueSkyPlan (Blue Sky Bio,美国)、Craniocatch (Craniocatch, t rkiye)、3D Slicer(美国开源)和Relu Creator (Relu BV,比利时)五个全自动人工智能分割平台,对120张匿名CBCT扫描(240 MCs)进行分析。专家注释模型作为参考。准确度被量化为无符号平均表面偏差,并被归类为最佳(2.0 mm)。定性评价采用五点解剖保真度量表。还评估了节段、侧位和扫描仪的效果。结果:不同平台间观察到显著的性能差异(p < 0.001)。Relu Creator和3D Slicer在全管分析中实现了最高的总体精度(≈0.5 mm),无>2.0 mm偏差。Craniocatch的准确度中等,而Atomica和BlueSkyPlan表现出更大的可变性和更大的偏差,达到2.0 mm。定性评分反映了类似的趋势。从区域上看,中椎管段的准确性最好,下颌孔和颏孔附近的偏差较高。扫描和副作用有统计学意义,但临床上可以忽略不计。结论:基于人工智能的MC分割准确率在不同平台存在差异。Relu Creator和3D切片器实现了适合临床使用的近乎专家的性能,而其他则需要专家验证。独立的基准测试和多扫描仪验证对于安全实现至关重要。临床意义:本研究为自动化MC分割的人工智能工具的准确性提供了基于证据的指导,通过确定哪些人工智能生成的输出可以信任,以及专家验证对预防神经损伤仍然至关重要,从而支持更安全的手术计划。
{"title":"Comparative analysis of five AI platforms for mandibular canal segmentation on CBCT images","authors":"Sohaib Shujaat ,&nbsp;Razan Alotaibi ,&nbsp;Amal Aldakhil ,&nbsp;Bassam Al Alola ,&nbsp;Wael Abolemaaty ,&nbsp;Paramjit Khinda ,&nbsp;Safa Saeed ,&nbsp;Randa Ibrahim ,&nbsp;Ali Anwar Aboalela ,&nbsp;Kaan Orhan ,&nbsp;Nermin Morgan","doi":"10.1016/j.jdent.2026.106345","DOIUrl":"10.1016/j.jdent.2026.106345","url":null,"abstract":"<div><h3>Objectives</h3><div>Accurate mandibular canal (MC) identification on cone-beam computed tomography (CBCT) is vital to prevent inferior alveolar nerve injury during oral and maxillofacial procedures. Manual segmentation is time-consuming and operator-dependent, while artificial intelligence (AI) offers automated, reproducible alternatives. This study compared the accuracy of automated MC segmentation across five AI platforms using standardized quantitative and qualitative evaluations.</div></div><div><h3>Methods</h3><div>A total of 120 anonymized CBCT scans (240 MCs) were analyzed using five fully automated AI-based segmentation platforms: Atomica (Atomica AI, USA), BlueSkyPlan (Blue Sky Bio, USA), Craniocatch (Craniocatch, Türkiye), 3D Slicer (open-source, USA), and Relu Creator (Relu BV, Belgium). Expert-annotated models served as reference. Accuracy was quantified as unsigned mean surface deviation and categorized as optimal (&lt;0.5 mm), acceptable (0.5–2.0 mm), or unacceptable (&gt;2.0 mm). Qualitative evaluation employed a five-point anatomical fidelity scale. Segment-wise, laterality, and scanner-wise effects were also assessed.</div></div><div><h3>Results</h3><div>Significant performance differences were observed among platforms (p &lt; 0.001). Relu Creator and 3D Slicer achieved the highest overall accuracy (≈0.5 mm) with no &gt;2.0 mm deviations in the complete-canal analysis. Craniocatch showed moderate accuracy, while Atomica and BlueSkyPlan exhibited greater variability and more deviations &gt; 2.0 mm. Qualitative scores reflected similar trends. Regionally, middle canal segments showed the best accuracy, with higher deviations near the mandibular and mental foramina. Scanner- and side-related effects were statistically significant but clinically negligible.</div></div><div><h3>Conclusion</h3><div>AI-based MC segmentation accuracy varies across platforms. Relu Creator and 3D Slicer achieved near-expert performance suitable for clinical use, while others require expert verification. Independent benchmarking and multi-scanner validation are essential for safe implementation.</div></div><div><h3>Clinical significance</h3><div>This study provides evidence-based guidance on the accuracy of AI tools for automated MC segmentation, supporting safer surgical planning by identifying which AI-generated outputs can be trusted and where expert verification remains essential to prevent nerve injury.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"166 ","pages":"Article 106345"},"PeriodicalIF":5.5,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145944235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining the influence of parathyroid hormone-doped nanoparticles on resin-dentin interface strength and composition 研究了甲状旁腺激素掺杂纳米颗粒对树脂-牙本质界面强度和组成的影响。
IF 5.5 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-06 DOI: 10.1016/j.jdent.2026.106340
Raquel Osorio, Fátima S. Aguilera, Enrique Fernández-Romero, Raquel Toledano, María T. Osorio, Manuel Toledano, Estrella Osorio

Objectives

This study aims to determine the remineralization capacity of etched dentin treated with polymeric nanoparticles (NPs) functionalized with parathyroid hormone (PTH) (PTH-NPs).

Methods

Dentin etched surfaces were treated with NPs and PTH-NPs. Treated interfaces were 24 h stored and, then, mechanically or thermally loaded. Interfaces were assessed through modulus of Young, Raman analysis and Masson’s trichrome staining microscopy.

Results

Specimens treated with PTH-NPs infiltration which were load cycled attained the highest modulus of Young. Remineralization throughout the total resin-dentin interface, referred to both phosphate and carbonate ions was unveiled in presence of PTH and dynamic loading, forming peritubular and intertubular dentin. The absence of NPs at the interface conditioned a scarce remineralization. After thermocycling, phosphate remineralization diminished at the interface in all groups, and carbonate only increased in the control group. Load cycling produced a higher minerals content and a major collagen crosslinking, contributing to generally augment both the mineral to matrix ratio and crystallinity.

Conclusions

PTH-NPs provoked a higher modulus of Young and a lower unprotected collagen web after conditioning and further resin infiltration, in load cycled samples. After dynamic load cycling, amorphous mineral was lower at the resin dentin interface, and crystallinity relative to phosphate was also greater after thermocycling at both hybrid layer and bottom of hybrid layer in case of PTH-NPs infiltration.

Clinical significance

Parathyroid hormone dentin infiltration, after phosphoric acid conditioning, has facilitated the reparative dentin formation at the resin-dentin interface, based on the nucleation of a more mature and soluble hydroxyapatite which facilitated remineralization.
目的:研究以甲状旁腺激素(PTH)功能化的聚合物纳米颗粒(NPs)处理牙本质后的再矿化能力。方法:用NPs和PTH-NPs处理牙本质腐蚀面。处理后的界面储存24小时,然后进行机械或热加载。通过杨氏模量、拉曼分析和马松三色染色显微镜评估界面。结果:经负荷循环的PTH-NPs浸渍处理的标本杨氏模量最高。再矿化贯穿整个树脂-牙本质界面,涉及磷酸盐和碳酸盐离子,在PTH和动态负载的存在下被揭开,形成管周和管间牙本质。界面处NPs的缺失使再矿化变得稀缺。热循环后,各实验组界面处磷酸盐再矿化减少,对照组仅碳酸盐增加。负载循环产生更高的矿物质含量和主要的胶原交联,通常有助于增加矿物质与基质的比例和结晶度。结论:在负荷循环的样品中,经过调理和进一步的树脂浸润后,PTH-NPs引起了更高的杨氏模量和更低的无保护胶原网。动态载荷循环后,树脂牙本质界面处的无定形矿物含量较低,在PTH-NPs渗透的情况下,杂化层和杂化层底部的热循环后相对于磷酸盐的结晶度也较大。临床意义:甲状旁腺激素牙本质浸润,经磷酸调理后,在树脂-牙本质界面形成修复性牙本质,形成更成熟、可溶的羟基磷灰石,促进再矿化。
{"title":"Examining the influence of parathyroid hormone-doped nanoparticles on resin-dentin interface strength and composition","authors":"Raquel Osorio,&nbsp;Fátima S. Aguilera,&nbsp;Enrique Fernández-Romero,&nbsp;Raquel Toledano,&nbsp;María T. Osorio,&nbsp;Manuel Toledano,&nbsp;Estrella Osorio","doi":"10.1016/j.jdent.2026.106340","DOIUrl":"10.1016/j.jdent.2026.106340","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aims to determine the remineralization capacity of etched dentin treated with polymeric nanoparticles (NPs) functionalized with parathyroid hormone (PTH) (PTH-NPs).</div></div><div><h3>Methods</h3><div>Dentin etched surfaces were treated with NPs and PTH-NPs. Treated interfaces were 24 h stored and, then, mechanically or thermally loaded. Interfaces were assessed through modulus of Young, Raman analysis and Masson’s trichrome staining microscopy.</div></div><div><h3>Results</h3><div>Specimens treated with PTH-NPs infiltration which were load cycled attained the highest modulus of Young. Remineralization throughout the total resin-dentin interface, referred to both phosphate and carbonate ions was unveiled in presence of PTH and dynamic loading, forming peritubular and intertubular dentin. The absence of NPs at the interface conditioned a scarce remineralization. After thermocycling, phosphate remineralization diminished at the interface in all groups, and carbonate only increased in the control group. Load cycling produced a higher minerals content and a major collagen crosslinking, contributing to generally augment both the mineral to matrix ratio and crystallinity.</div></div><div><h3>Conclusions</h3><div>PTH-NPs provoked a higher modulus of Young and a lower unprotected collagen web after conditioning and further resin infiltration, in load cycled samples. After dynamic load cycling, amorphous mineral was lower at the resin dentin interface, and crystallinity relative to phosphate was also greater after thermocycling at both hybrid layer and bottom of hybrid layer in case of PTH-NPs infiltration.</div></div><div><h3>Clinical significance</h3><div>Parathyroid hormone dentin infiltration, after phosphoric acid conditioning, has facilitated the reparative dentin formation at the resin-dentin interface, based on the nucleation of a more mature and soluble hydroxyapatite which facilitated remineralization.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"166 ","pages":"Article 106340"},"PeriodicalIF":5.5,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From peri-implant mucositis to peri-implantitis: Incidence and risk indicators in a university dental hospital sample with up to 10 years of follow-up 从种植体周围粘膜炎到种植体周围炎:大学牙科医院样本的发病率和风险指标长达10年的随访。
IF 5.5 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-06 DOI: 10.1016/j.jdent.2026.106339
Ahmad Alahmari , Amir Arsalan-Askarizadeh , Rui Figueiredo , Marta García-García , Xavier Costa-Berenguer , Miquel Sales-Collado , Eduard Valmaseda-Castellón , Alba Sánchez-Torres

Objectives

To determine the proportion of patients with peri‑implant mucositis who develop peri‑implantitis over a 1- to 10-year follow-up period, and to identify the variables associated with this progression.

Materials and Methods

A retrospective cohort study was conducted including 97 patients with 204 dental implants diagnosed with peri‑implant mucositis. Clinical and radiographic examinations were performed, and compliance with supportive peri‑implant care (SPIC) was recorded. A multilevel multinomial logistic regression model was developed to identify the predictors of disease progression.

Results

After a mean follow-up of 49.8 months, 23.7% of patients initially diagnosed with peri‑implant mucositis became healthy, 57.7% showed no change and remained with peri‑implant mucositis, while 18.5% progressed to peri‑implantitis. A history of periodontitis significantly increased the odds of presenting peri‑implant disease at the last follow-up appointment (p < 0.001). Conversely, regular compliance with SPIC, prostheses with an adequate design, and single-unit restorations significantly reduced the risk of progression (p < 0.001).

Conclusions

Almost one fifth of patients with dental implants with peri‑implant mucositis are likely to develop peri‑implantitis after a mean follow-up of 4 years. A history of periodontitis, irregular supportive peri‑implant care and inadequate prosthetic design increase the likelihood of bone loss and progression to peri‑implantitis.

Clinical Significance

This study emphasizes the importance of regular supportive peri‑implant care and appropriate prosthetic design to prevent progression from peri‑implant mucositis to peri‑implantitis, especially in patients with a history of periodontitis.
目的:确定种植体周围粘膜炎患者在1- 10年随访期间发展为种植体周围炎的比例,并确定与这种进展相关的变量。材料与方法:回顾性队列研究,纳入97例种植体周围黏膜炎患者204例种植体。进行了临床和影像学检查,并记录了支持种植体周围护理(SPIC)的依从性。建立了一个多水平多项逻辑回归模型来确定疾病进展的预测因子。结果:平均随访49.8个月后,最初诊断为种植体周围粘膜炎的患者中,23.7%的患者恢复健康,57.7%的患者未发生变化并保持种植体周围粘膜炎,18.5%的患者进展为种植体周围炎。有牙周炎病史的患者在最后一次随访时出现种植体周围疾病的几率显著增加(结论:在平均随访4年后,近五分之一的种植体种植体周围粘膜炎患者可能发生种植体周围炎。牙周炎病史、不规范的种植周支持护理和不适当的假体设计增加了骨质流失和发展为种植周炎的可能性。临床意义:本研究强调了常规的种植周支持性护理和适当的假体设计对于防止种植周黏膜炎发展为种植周炎的重要性,特别是对于有牙周炎病史的患者。
{"title":"From peri-implant mucositis to peri-implantitis: Incidence and risk indicators in a university dental hospital sample with up to 10 years of follow-up","authors":"Ahmad Alahmari ,&nbsp;Amir Arsalan-Askarizadeh ,&nbsp;Rui Figueiredo ,&nbsp;Marta García-García ,&nbsp;Xavier Costa-Berenguer ,&nbsp;Miquel Sales-Collado ,&nbsp;Eduard Valmaseda-Castellón ,&nbsp;Alba Sánchez-Torres","doi":"10.1016/j.jdent.2026.106339","DOIUrl":"10.1016/j.jdent.2026.106339","url":null,"abstract":"<div><h3>Objectives</h3><div>To determine the proportion of patients with peri‑implant mucositis who develop peri‑implantitis over a 1- to 10-year follow-up period, and to identify the variables associated with this progression.</div></div><div><h3>Materials and Methods</h3><div>A retrospective cohort study was conducted including 97 patients with 204 dental implants diagnosed with peri‑implant mucositis. Clinical and radiographic examinations were performed, and compliance with supportive peri‑implant care (SPIC) was recorded. A multilevel multinomial logistic regression model was developed to identify the predictors of disease progression.</div></div><div><h3>Results</h3><div>After a mean follow-up of 49.8 months, 23.7% of patients initially diagnosed with peri‑implant mucositis became healthy, 57.7% showed no change and remained with peri‑implant mucositis, while 18.5% progressed to peri‑implantitis. A history of periodontitis significantly increased the odds of presenting peri‑implant disease at the last follow-up appointment (<em>p</em> &lt; 0.001). Conversely, regular compliance with SPIC, prostheses with an adequate design, and single-unit restorations significantly reduced the risk of progression (<em>p</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>Almost one fifth of patients with dental implants with peri‑implant mucositis are likely to develop peri‑implantitis after a mean follow-up of 4 years. A history of periodontitis, irregular supportive peri‑implant care and inadequate prosthetic design increase the likelihood of bone loss and progression to peri‑implantitis.</div></div><div><h3>Clinical Significance</h3><div>This study emphasizes the importance of regular supportive peri‑implant care and appropriate prosthetic design to prevent progression from peri‑implant mucositis to peri‑implantitis, especially in patients with a history of periodontitis.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"166 ","pages":"Article 106339"},"PeriodicalIF":5.5,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AI-driven gingival segmentation on CBCT: Validation using delineation by intraoral scanning and CBCT-based cotton roll separation 基于CBCT的人工智能驱动牙龈分割:使用口腔内扫描和基于CBCT的棉卷分离进行划分的验证。
IF 5.5 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-05 DOI: 10.1016/j.jdent.2026.106331
Fernanda Bulhões Fagundes , Dhanaporn Papasratorn , Bahaaeldeen M. Elgarba , Rocharles Cavalcante Fontenele , Frederico Sampaio Neves , Reinhilde Jacobs

Objectives

To validate a novel AI approach for automated gingival segmentation directly from cone beam computed tomography (CBCT) scans acquired with cotton roll separation.

Methods

One hundred and eighty arches (101 CBCT) were split into: ground truth (90 arches), internal validation [AI vs manual segmentation (MS); 30 arches], and clinical validation [AI vs expert refinement (R-AI); 60 arches]. Ground truth consisted of manually segmented gingival models from CBCT with cotton roll separation, using intraoral scan outlines as references. AI gingival segmentation was generated from CBCT acquired with cotton roll separation, uploaded to a cloud-based platform (Virtual Patient Creator, Relu, Belgium). R-AI was performed by refining the AI segmentation according to CBCT outlines. The performance was evaluated using voxel-wise and surface-based comparisons. Additionally, time efficiency and consistency were evaluated.

Results

AI gingiva achieved high overlap with MS, with Dice score (DSC) of 80 ± 4 % and minor surface discrepancies, with median surface distance (MSD) of 0.02 ± 0.09 mm. Similarly, DSC between AI and R-AI was high (91 ± 4 %), and MSD was small (0.07 ± 0.07 mm). Significant differences between arches were found in AI vs R-AI; however, these differences were not clinically relevant (∆DSC∼2 %, ∆MSD∼0.00 mm, p < 0.05). Evaluator consistency was high, whereas AI achieved perfect reproducibility and significantly increased time efficiency (6.7 s) compared to R-AI (1090 s) and MS (4344 s), p < 0.001.

Conclusion

The presently validated cloud-based AI model achieved fast, accurate, and consistent gingiva segmentation from CBCTs comparable to expert-level performance using CBCT-based cotton roll separation with delineation by intraoral scanning as a clinical reference.

Clinical significance

Automated 3D gingival models may assist efficient diagnosis, treatment planning, and outcome visualization in esthetic dentistry, orthodontic treatment planning, and periodontal assessment. This approach has strong potential to transform digital dentistry workflows.
目的:验证一种新的人工智能方法,直接从棉卷分离获得的锥束计算机断层扫描(CBCT)中自动分割牙龈。方法:180个拱形(101个CBCT)分为:基础真实(90个拱形),内部验证[人工智能vs人工分割(MS);30个拱门]和临床验证[人工智能与专家改进(R-AI);60个拱门。Ground truth由手工分割的CBCT牙龈模型组成,使用棉卷分离,以口腔内扫描轮廓为参考。人工智能牙龈分割由棉卷分离获得的CBCT生成,上传到基于云的平台(Virtual Patient Creator, Relu, Belgium)。R-AI是根据CBCT轮廓对AI分割进行细化。使用体素和基于表面的比较来评估性能。此外,时间效率和一致性进行了评估。结果:AI牙龈与MS重叠度高,Dice评分(DSC)为80±4%,表面差异较小,中位表面距离(MSD)为0.02±0.09 mm。同样,AI和R-AI之间的DSC高(91±4%),MSD小(0.07±0.07 mm)。在AI和R-AI中,弓间存在显著差异;然而,这些差异与临床无关(∆DSC ~ 2%,∆MSD ~ 0.00 mm, p)。结论:目前验证的基于云的人工智能模型通过cbct实现了快速、准确、一致的牙龈分割,与专家水平相当,使用基于cbct的棉卷分离,通过口腔内扫描作为临床参考。临床意义:在牙科美容、正畸治疗计划和牙周评估中,自动三维牙龈模型可以帮助有效的诊断、治疗计划和结果可视化。这种方法具有改变数字牙科工作流程的强大潜力。
{"title":"AI-driven gingival segmentation on CBCT: Validation using delineation by intraoral scanning and CBCT-based cotton roll separation","authors":"Fernanda Bulhões Fagundes ,&nbsp;Dhanaporn Papasratorn ,&nbsp;Bahaaeldeen M. Elgarba ,&nbsp;Rocharles Cavalcante Fontenele ,&nbsp;Frederico Sampaio Neves ,&nbsp;Reinhilde Jacobs","doi":"10.1016/j.jdent.2026.106331","DOIUrl":"10.1016/j.jdent.2026.106331","url":null,"abstract":"<div><h3>Objectives</h3><div>To validate a novel AI approach for automated gingival segmentation directly from cone beam computed tomography (CBCT) scans acquired with cotton roll separation.</div></div><div><h3>Methods</h3><div>One hundred and eighty arches (101 CBCT) were split into: ground truth (90 arches), internal validation [AI vs manual segmentation (MS); 30 arches], and clinical validation [AI vs expert refinement (R-AI); 60 arches]. Ground truth consisted of manually segmented gingival models from CBCT with cotton roll separation, using intraoral scan outlines as references. AI gingival segmentation was generated from CBCT acquired with cotton roll separation, uploaded to a cloud-based platform (Virtual Patient Creator, Relu, Belgium). R-AI was performed by refining the AI segmentation according to CBCT outlines. The performance was evaluated using voxel-wise and surface-based comparisons. Additionally, time efficiency and consistency were evaluated.</div></div><div><h3>Results</h3><div>AI gingiva achieved high overlap with MS, with Dice score (DSC) of 80 ± 4 % and minor surface discrepancies, with median surface distance (MSD) of 0.02 ± 0.09 mm. Similarly, DSC between AI and R-AI was high (91 ± 4 %), and MSD was small (0.07 ± 0.07 mm). Significant differences between arches were found in AI vs R-AI; however, these differences were not clinically relevant (∆DSC∼2 %, ∆MSD∼0.00 mm, <em>p</em> &lt; 0.05). Evaluator consistency was high, whereas AI achieved perfect reproducibility and significantly increased time efficiency (6.7 s) compared to R-AI (1090 s) and MS (4344 s), <em>p</em> &lt; 0.001.</div></div><div><h3>Conclusion</h3><div>The presently validated cloud-based AI model achieved fast, accurate, and consistent gingiva segmentation from CBCTs comparable to expert-level performance using CBCT-based cotton roll separation with delineation by intraoral scanning as a clinical reference.</div></div><div><h3>Clinical significance</h3><div>Automated 3D gingival models may assist efficient diagnosis, treatment planning, and outcome visualization in esthetic dentistry, orthodontic treatment planning, and periodontal assessment. This approach has strong potential to transform digital dentistry workflows.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"166 ","pages":"Article 106331"},"PeriodicalIF":5.5,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145917677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The development of an image processing model to estimate tooth width and space requirements 开发了一种图像处理模型来估计齿宽和空间要求。
IF 5.5 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-03 DOI: 10.1016/j.jdent.2026.106330
Rebecca Toner , Moses Eribo , Bahman Honari , Kieran Daly , Padhraig S. Fleming

Objectives

The advent of machine and deep learning has raised the possibility of increased efficiency and indeed improved accuracy in relation to the interpretation of clinical images. Moreover, the use of deep learning has become imbedded within orthodontics with attempts to utilise this approach in informing treatment planning. The aim of this study was to develop and test an AI-based tool capable of measuring tooth width and dental crowding.

Methodology

Sets of pre and post treatment plaster study models were acquired of 245 patients who had treatment completed in a specialist orthodontic practice by a single orthodontist. These models were scanned to create stereolithography (STL) files. These files were used to train an AI tool capable of calculating the mesio-distal widths of each of the teeth in the arches. To test the validity of this model, direct comparison was made between the AI tool and human raters. A sample of twelve sets of pre-treatment study models were known as the “test data”. The test data was analysed by a group of five orthodontic clinicians at two separate time intervals 6 weeks apart.

Results

Statistical analysis confirmed a high level of agreement between human raters and also in relation to the novel AI-based tool. Inter-rater reliability among the human raters was high with Intraclass correlation coefficients (ICCs) ranging from 0.911 to 0.946 between the intervals. Manual measurements also demonstrated a high level of agreement with the AI tool (ICC= 0.956; Mean absolute difference= 0.4 mm).

Conclusions

The novel AI-based tool demonstrated reliability in calculating mesiodistal widths of teeth in an untreated arch. This tool will be further developed to incorporate other parameters such as arch levelling, to provide a means to calculate the overall space requirement within the dental arches.
目的:机器和深度学习的出现提高了临床图像解释的效率和准确性的可能性。此外,深度学习的使用已经嵌入到正畸学中,试图利用这种方法为治疗计划提供信息。本研究的目的是开发和测试一种基于人工智能的工具,能够测量牙齿宽度和牙齿拥挤程度。方法:获得245名患者的治疗前后石膏研究模型,这些患者在专科正畸诊所由一名正畸医生完成治疗。这些模型被扫描以创建立体光刻(STL)文件。这些文件被用来训练一个人工智能工具,该工具能够计算出弓中每颗牙齿的中远端宽度。为了测试该模型的有效性,将人工智能工具与人类评分者进行了直接比较。12组预处理研究模型的样本被称为“测试数据”。测试数据由一组五名正畸临床医生在相隔6周的两个不同的时间间隔进行分析。结果:统计分析证实了人类评分者之间的高度一致,也与新的基于人工智能的工具有关。人类评分者的等级间信度较高,等级内相关系数(ICCs)在0.911 ~ 0.946之间。人工测量也显示出与人工智能工具的高度一致(ICC= 0.956;平均绝对差= 0.4 mm)。结论:新型人工智能工具在计算未治疗弓的中远端牙齿宽度方面表现出可靠性。我们会进一步发展此工具,以纳入其他参数,例如拱的水准,以提供一种计算拱的整体空间需求的方法。
{"title":"The development of an image processing model to estimate tooth width and space requirements","authors":"Rebecca Toner ,&nbsp;Moses Eribo ,&nbsp;Bahman Honari ,&nbsp;Kieran Daly ,&nbsp;Padhraig S. Fleming","doi":"10.1016/j.jdent.2026.106330","DOIUrl":"10.1016/j.jdent.2026.106330","url":null,"abstract":"<div><h3>Objectives</h3><div>The advent of machine and deep learning has raised the possibility of increased efficiency and indeed improved accuracy in relation to the interpretation of clinical images. Moreover, the use of deep learning has become imbedded within orthodontics with attempts to utilise this approach in informing treatment planning. The aim of this study was to develop and test an AI-based tool capable of measuring tooth width and dental crowding.</div></div><div><h3>Methodology</h3><div>Sets of pre and post treatment plaster study models were acquired of 245 patients who had treatment completed in a specialist orthodontic practice by a single orthodontist. These models were scanned to create stereolithography (STL) files. These files were used to train an AI tool capable of calculating the mesio-distal widths of each of the teeth in the arches. To test the validity of this model, direct comparison was made between the AI tool and human raters. A sample of twelve sets of pre-treatment study models were known as the “test data”. The test data was analysed by a group of five orthodontic clinicians at two separate time intervals 6 weeks apart.</div></div><div><h3>Results</h3><div>Statistical analysis confirmed a high level of agreement between human raters and also in relation to the novel AI-based tool. Inter-rater reliability among the human raters was high with Intraclass correlation coefficients (ICCs) ranging from 0.911 to 0.946 between the intervals. Manual measurements also demonstrated a high level of agreement with the AI tool (ICC= 0.956; Mean absolute difference= 0.4 mm).</div></div><div><h3>Conclusions</h3><div>The novel AI-based tool demonstrated reliability in calculating mesiodistal widths of teeth in an untreated arch. This tool will be further developed to incorporate other parameters such as arch levelling, to provide a means to calculate the overall space requirement within the dental arches.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"166 ","pages":"Article 106330"},"PeriodicalIF":5.5,"publicationDate":"2026-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145906086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does the use of intermediate abutments impact screw-retained implant-supported fixed partial prostheses outcomes? A systematic review and meta-analysis of randomized controlled trials 使用中间基台会影响螺钉保留种植体支持的固定部分假体的效果吗?随机对照试验的系统回顾和荟萃分析。
IF 5.5 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-02 DOI: 10.1016/j.jdent.2026.106328
Pedro Molinero-Mourelle , Alvaro Limones , Seyed Ali Mosaddad , Gabriela Panca Sabatini , Maria Menini , Paolo Pesce , Andrea Roccuzzo

Objectives

To evaluate the impact of intermediate abutments on screw-retained implant-supported fixed dental prostheses (FDPs), primarily assessing marginal bone loss (MBL) and secondarily probing depth (PD), bleeding on probing (BoP), implant survival, mechanical complications, and patient satisfaction.

Data

Random-effects meta-analyses were conducted using weighted mean differences (MD) for continuous outcomes and risk differences for dichotomous outcomes. Risk of bias was assessed using the Cochrane RoB 2 tool, and the certainty of evidence (CoE) using the GRADE approach.

Sources

A systematic search was conducted up to May 2025 across MEDLINE (PubMed), Scopus, Web of Science, Cochrane Library, Embase, and Google Scholar.

Study selection

Randomized controlled trials (RCTs) with ≥6 months of follow-up comparing abutment-level (AL) versus implant-level (IL) connections in partially edentulous patients rehabilitated with screw-retained FDPs.

Results

Three RCTs (8 publications) with different follow-up periods, involving a total of 126 patients and 341 implants, were included. A statistically significant reduction in MBL was observed at 36 months at implant level (MD:-0.13 mm; 95% CI: −0.23 to −0.03; p=0.01; 2 RCTs; 162 implants; moderate CoE). No significant differences in MBL were observed at 12 or 60 months. PD was significantly reduced in the AL group at 36 months (MD:−0.66 mm; 95% CI: −1.13 to −0.19; p=0.01; 2 RCTs; 187 implants; low CoE) and at 60 months (MD:−0.60 mm; 95% CI: −0.91 to −0.29; p<0.001; 1 RCT; 115 implants; low CoE). No significant differences were found in BoP, implant survival, mechanical complications, or patient satisfaction at any follow-up time point.

Conclusions

Intermediate abutments may improve soft-tissue health by reducing PD without increasing complications or implant failure. Despite a minor, non-clinically relevant reduction in MBL, they remain a viable option for screw-retained FDPs.

Clinical Relevance

Intermediate abutments slightly reduce probing depth and marginal bone loss in multi-unit implant prostheses, but the clinical impact is minimal, with no effect on implant survival or mechanical complications.

PROSPERO registration

CRD42023475778.
目的:评估中间基台对螺钉保留种植体支持固定义齿(fdp)的影响,主要评估边缘骨丢失(MBL)和继发性探探深度(PD)、探探出血(BoP)、种植体存活、机械并发症和患者满意度。数据:随机效应荟萃分析采用加权平均差异(WMD)对连续结局和风险差异对二分类结局进行。使用Cochrane RoB 2工具评估偏倚风险,使用GRADE方法评估证据确定性(CoE)。资料来源:到2025年5月,通过MEDLINE (PubMed)、Scopus、Web of Science、Cochrane Library、Embase和谷歌Scholar进行了系统搜索。研究选择:随机对照试验(rct),随访≥6个月,比较使用螺钉保留fdp康复的部分无牙患者的基台水平(AL)与种植水平(IL)连接。结果:纳入3项随机对照试验(8篇发表),随访时间不同,共126例患者,341颗种植体。在种植体水平上观察到MBL在36个月时有统计学意义的减少(MD:-0.13 mm; 95% CI: -0.23至-0.03;p=0.01; 2个随机对照试验;162个种植体;中度CoE)。12个月或60个月时MBL无显著差异。AL组PD在36个月(MD:-0.66 mm; 95% CI: -1.13至-0.19;p=0.01; 2个随机对照试验;187个种植体;低CoE)和60个月(MD:-0.60 mm; 95% CI: -0.91至-0.29;p)时显著降低,结论:中间基台可以通过减少PD而改善软组织健康,而不会增加并发症或种植体失败。尽管MBL有轻微的、非临床相关的减少,但它们仍然是螺钉保留fdp的可行选择。临床相关性:在多单元种植体修复中,中间基台略微减少探探深度和边缘骨丢失,但临床影响很小,对种植体存活或机械并发症没有影响。普洛斯彼罗注册:CRD42023475778。
{"title":"Does the use of intermediate abutments impact screw-retained implant-supported fixed partial prostheses outcomes? A systematic review and meta-analysis of randomized controlled trials","authors":"Pedro Molinero-Mourelle ,&nbsp;Alvaro Limones ,&nbsp;Seyed Ali Mosaddad ,&nbsp;Gabriela Panca Sabatini ,&nbsp;Maria Menini ,&nbsp;Paolo Pesce ,&nbsp;Andrea Roccuzzo","doi":"10.1016/j.jdent.2026.106328","DOIUrl":"10.1016/j.jdent.2026.106328","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the impact of intermediate abutments on screw-retained implant-supported fixed dental prostheses (FDPs), primarily assessing marginal bone loss (MBL) and secondarily probing depth (PD), bleeding on probing (BoP), implant survival, mechanical complications, and patient satisfaction.</div></div><div><h3>Data</h3><div>Random-effects meta-analyses were conducted using weighted mean differences (MD) for continuous outcomes and risk differences for dichotomous outcomes. Risk of bias was assessed using the Cochrane RoB 2 tool, and the certainty of evidence (CoE) using the GRADE approach.</div></div><div><h3>Sources</h3><div>A systematic search was conducted up to May 2025 across MEDLINE (PubMed), Scopus, Web of Science, Cochrane Library, Embase, and Google Scholar.</div></div><div><h3>Study selection</h3><div>Randomized controlled trials (RCTs) with ≥6 months of follow-up comparing abutment-level (AL) versus implant-level (IL) connections in partially edentulous patients rehabilitated with screw-retained FDPs.</div></div><div><h3>Results</h3><div>Three RCTs (8 publications) with different follow-up periods, involving a total of 126 patients and 341 implants, were included. A statistically significant reduction in MBL was observed at 36 months at implant level (MD:-0.13 mm; 95% CI: −0.23 to −0.03; <em>p</em>=0.01; 2 RCTs; 162 implants; moderate CoE). No significant differences in MBL were observed at 12 or 60 months. PD was significantly reduced in the AL group at 36 months (MD:−0.66 mm; 95% CI: −1.13 to −0.19; <em>p</em>=0.01; 2 RCTs; 187 implants; low CoE) and at 60 months (MD:−0.60 mm; 95% CI: −0.91 to −0.29; <em>p</em>&lt;0.001; 1 RCT; 115 implants; low CoE). No significant differences were found in BoP, implant survival, mechanical complications, or patient satisfaction at any follow-up time point.</div></div><div><h3>Conclusions</h3><div>Intermediate abutments may improve soft-tissue health by reducing PD without increasing complications or implant failure. Despite a minor, non-clinically relevant reduction in MBL, they remain a viable option for screw-retained FDPs.</div></div><div><h3>Clinical Relevance</h3><div>Intermediate abutments slightly reduce probing depth and marginal bone loss in multi-unit implant prostheses, but the clinical impact is minimal, with no effect on implant survival or mechanical complications.</div></div><div><h3>PROSPERO registration</h3><div>CRD42023475778.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"166 ","pages":"Article 106328"},"PeriodicalIF":5.5,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bio-inspired nacre-like glass flake/polymer composites with antibacterial function and translucent appearance 仿生珍珠状玻璃片/聚合物复合材料,具有抗菌功能和半透明外观。
IF 5.5 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-02 DOI: 10.1016/j.jdent.2025.106327
Huijun Sun , Aukrit Luangpattarawong , Parinaz Tabrizian , Aqsa Qambrani , Tan Sui , Angela H. Nobbs , Tony Ireland , Bo Su

Objectives

This study aims to develop a bio-inspired nacre-like glass flake/polymer composite with enhanced mechanical properties, antibacterial function, and aesthetic appearance for potential dental applications.

Methods

Self-assembly via vacuum filtration was used to align glass flakes into a layered structure. After heat treatment, monomers containing methyl methacrylate (MMA), acrylic acid (AA) and dimethylaminohexadecyl methacrylate (DMAHDM) were infiltrated into the glass flake scaffold and polymerised in situ. The nacre-like microstructure of the composites was characterised and mechanical tests, including flexural strength, elastic modulus and fracture toughness, were conducted to optimise the DMAHDM content (0, 1.5wt%, and 3 wt%). The antibacterial function of the optimised composite with 1.5 wt% DMAHDM was measured by viable colony-forming unit (CFU) count. Finally, the translucency of the composite with 1.5 wt% DMAHDM was determined.

Results

The glass flake/polymer composites with different DMAHDM contents all exhibited nacre-like layered microstructures. Adding 3 wt% DMAHDM was shown to significantly lower the flexural strength of the composites. The composite with 1.5 wt% DMAHDM exhibited a flexural strength of 126.97 MPa, comparable to the current benchmark aesthetic dental composite. Moreover, the elastic modulus of the composite with 1.5 wt% DMAHDM (24.75 GPa) was similar to that of human dentine, presenting bio-inspired mechanical property. Its unique crack resistance, characterised by a rising R-curve behaviour and a fracture toughness KJ up to 3.88 MPa.m½, suggested excellent damage tolerance. With the addition of 1.5 wt% DMAHDM, the nacre-like composite demonstrated significant antibacterial function against Streptococcus mutans. Furthermore, the composite retained an aesthetic appearance with a translucency comparable to human enamel.

Significance

A bio-inspired nacre-like glass flake/polymer composite with good mechanical properties, unique crack resistance, antibacterial function and translucency has been developed for aesthetic dental applications.
目的:本研究旨在开发一种具有增强机械性能,抗菌功能和美观外观的仿生珍珠状玻璃片/聚合物复合材料,用于潜在的牙科应用。方法:采用真空过滤的自组装方法将玻璃薄片排列成层状结构。热处理后,将含有甲基丙烯酸甲酯(MMA)、丙烯酸(AA)和甲基丙烯酸二甲基胺十六烷基(DMAHDM)的单体渗透到玻璃鳞片支架中并原位聚合。表征了复合材料的珍珠状微观结构,并进行了力学测试,包括抗弯强度、弹性模量和断裂韧性,以优化DMAHDM含量(0、1.5wt%和3 wt%)。采用菌落形成单位(CFU)计数法测定添加1.5% DMAHDM的优化复合材料的抑菌功能。最后,测定了加入1.5 wt% DMAHDM的复合材料的透光率。结果:不同DMAHDM含量的玻璃片/聚合物复合材料均表现出类似珠粒的层状微结构。结果表明,添加3 wt%的DMAHDM可显著降低复合材料的抗弯强度。含有1.5 wt% DMAHDM的复合材料显示出126.97 MPa的弯曲强度,与目前的基准美学牙科复合材料相当。此外,添加1.5 wt% DMAHDM (24.75 GPa)的复合材料的弹性模量与人牙本质相似,具有仿生力学性能。其独特的抗裂性能,其特征是上升的r曲线行为和断裂韧性KJ高达3.88 MPa。M½,建议极好的损伤容忍度。添加1.5 wt%的DMAHDM后,纳米状复合材料对变形链球菌具有明显的抗菌作用。此外,该复合材料保留了与人类牙釉质相当的半透明美学外观。意义:研制出一种具有良好力学性能、独特抗裂性、抗菌功能和半透明性的仿生类珍珠状玻璃片/聚合物复合材料,用于牙科美容。
{"title":"Bio-inspired nacre-like glass flake/polymer composites with antibacterial function and translucent appearance","authors":"Huijun Sun ,&nbsp;Aukrit Luangpattarawong ,&nbsp;Parinaz Tabrizian ,&nbsp;Aqsa Qambrani ,&nbsp;Tan Sui ,&nbsp;Angela H. Nobbs ,&nbsp;Tony Ireland ,&nbsp;Bo Su","doi":"10.1016/j.jdent.2025.106327","DOIUrl":"10.1016/j.jdent.2025.106327","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aims to develop a bio-inspired nacre-like glass flake/polymer composite with enhanced mechanical properties, antibacterial function, and aesthetic appearance for potential dental applications.</div></div><div><h3>Methods</h3><div>Self-assembly via vacuum filtration was used to align glass flakes into a layered structure. After heat treatment, monomers containing methyl methacrylate (MMA), acrylic acid (AA) and dimethylaminohexadecyl methacrylate (DMAHDM) were infiltrated into the glass flake scaffold and polymerised in situ. The nacre-like microstructure of the composites was characterised and mechanical tests, including flexural strength, elastic modulus and fracture toughness, were conducted to optimise the DMAHDM content (0, 1.5wt%, and 3 wt%). The antibacterial function of the optimised composite with 1.5 wt% DMAHDM was measured by viable colony-forming unit (CFU) count. Finally, the translucency of the composite with 1.5 wt% DMAHDM was determined.</div></div><div><h3>Results</h3><div>The glass flake/polymer composites with different DMAHDM contents all exhibited nacre-like layered microstructures. Adding 3 wt% DMAHDM was shown to significantly lower the flexural strength of the composites. The composite with 1.5 wt% DMAHDM exhibited a flexural strength of 126.97 MPa, comparable to the current benchmark aesthetic dental composite. Moreover, the elastic modulus of the composite with 1.5 wt% DMAHDM (24.75 GPa) was similar to that of human dentine, presenting bio-inspired mechanical property. Its unique crack resistance, characterised by a rising <em>R</em>-curve behaviour and a fracture toughness <em>K<sub>J</sub></em> up to 3.88 MPa.m<sup>½</sup>, suggested excellent damage tolerance. With the addition of 1.5 wt% DMAHDM, the nacre-like composite demonstrated significant antibacterial function against <em>Streptococcus mutans</em>. Furthermore, the composite retained an aesthetic appearance with a translucency comparable to human enamel.</div></div><div><h3>Significance</h3><div>A bio-inspired nacre-like glass flake/polymer composite with good mechanical properties, unique crack resistance, antibacterial function and translucency has been developed for aesthetic dental applications.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"166 ","pages":"Article 106327"},"PeriodicalIF":5.5,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of pulpotomy compared with pulpectomy for irreversible pulpitis in primary teeth: A systematic review and meta-analysis 牙髓切开术与牙髓切开术治疗乳牙不可逆牙髓炎的疗效比较:一项系统综述和荟萃分析。
IF 5.5 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-02 DOI: 10.1016/j.jdent.2026.106329
Shiwani Chawla , Ruchi Singhal , Ritu Namdev , Adarsh Kumar , Khusboo Chhanna , Chanchal Kumari

Introduction and objective

Pulpotomy is increasingly explored as a minimally invasive alternative to pulpectomy for managing irreversible pulpitis in primary teeth. However, its comparative effectiveness remains unclear. This systematic review aims to compare the clinical and radiographic success of pulpotomy versus pulpectomy in primary teeth with irreversible pulpitis.

Study selection and sources

A detailed search of six electronic databases up to April 2025 identified studies comparing pulpotomy and pulpectomy in primary teeth with symptomatic or asymptomatic irreversible pulpitis, excluding cases with swelling, sinus tract, furcal or periapical radiolucency, or root resorption, and with a minimum follow-up of 12 months. Two studies met the inclusion criteria: one randomized controlled trial (RCT) and one retrospective cohort study. Meta-analyses were done through random-effects model.

Results

For radiographic success, the pooled risk ratio (RR) was 1.35 (95 % CI: 0.67–2.73; p value = 0.40), with no significant difference between the two treatments. However, it showed very high heterogeneity, I² = 96 %. For clinical success, the pooled RR was 1.06 (95 % CI: 0.95–1.18; p value = 0.28), again showing no significant difference, with heterogeneity, I² = 66 %.

Conclusions

The review revealed no statistically significant difference between the two treatment modalities for managing irreversible pulpitis in primary teeth without clinical signs of swelling or radiographic evidence of periapical infection up to 12 months of follow-up. However, certainty of evidence was very low for both the outcomes.

Clinical significance

Pulpotomy appears to be an effective, minimally invasive alternative to pulpectomy in primary teeth with irreversible pulpitis. However, further well-designed, long-term studies are recommended.
简介与目的:牙髓切开术作为治疗乳牙不可逆性牙髓炎的一种微创替代方法被越来越多地探索。然而,其相对有效性仍不清楚。本系统综述的目的是比较牙髓切开术与牙髓切开术治疗不可逆性牙髓炎的临床和影像学成功。研究选择和来源:截至2025年4月,对6个电子数据库进行了详细的检索,确定了比较牙髓切开术和牙髓切开术治疗有症状或无症状的不可逆牙髓炎的研究,排除了肿胀、窦道、分叉或根尖周放射性或牙根吸收的病例,并且至少随访12个月。两项研究符合纳入标准:一项随机对照试验(RCT)和一项回顾性队列研究。采用随机效应模型进行meta分析。结果:对于放射治疗成功,合并风险比(RR)为1.35 (95% CI: 0.67-2.73; p值 = 0.40),两种治疗之间无显著差异。但其异质性非常高,I² = 96%。对于临床成功,合并RR为1.06 (95% CI: 0.95 ~ 1.18; p值 = 0.28),同样无显著差异,存在异质性,I² = 66%。结论:在12个月的随访中,两种治疗方式在治疗无临床肿胀症状或根尖周感染的乳牙不可逆性牙髓炎方面没有统计学差异。然而,这两种结果的证据确定性都很低。临床意义:对于不可逆牙髓炎的乳牙,牙髓切开术是一种有效的、微创的替代牙髓切开术。然而,建议进行进一步精心设计的长期研究。
{"title":"Effectiveness of pulpotomy compared with pulpectomy for irreversible pulpitis in primary teeth: A systematic review and meta-analysis","authors":"Shiwani Chawla ,&nbsp;Ruchi Singhal ,&nbsp;Ritu Namdev ,&nbsp;Adarsh Kumar ,&nbsp;Khusboo Chhanna ,&nbsp;Chanchal Kumari","doi":"10.1016/j.jdent.2026.106329","DOIUrl":"10.1016/j.jdent.2026.106329","url":null,"abstract":"<div><h3>Introduction and objective</h3><div>Pulpotomy is increasingly explored as a minimally invasive alternative to pulpectomy for managing irreversible pulpitis in primary teeth. However, its comparative effectiveness remains unclear. This systematic review aims to compare the clinical and radiographic success of pulpotomy versus pulpectomy in primary teeth with irreversible pulpitis.</div></div><div><h3>Study selection and sources</h3><div>A detailed search of six electronic databases up to April 2025 identified studies comparing pulpotomy and pulpectomy in primary teeth with symptomatic or asymptomatic irreversible pulpitis, excluding cases with swelling, sinus tract, furcal or periapical radiolucency, or root resorption, and with a minimum follow-up of 12 months. Two studies met the inclusion criteria: one randomized controlled trial (RCT) and one retrospective cohort study. Meta-analyses were done through random-effects model.</div></div><div><h3>Results</h3><div>For radiographic success, the pooled risk ratio (RR) was 1.35 (95 % CI: 0.67–2.73; p value = 0.40), with no significant difference between the two treatments. However, it showed very high heterogeneity, I² = 96 %. For clinical success, the pooled RR was 1.06 (95 % CI: 0.95–1.18; p value = 0.28), again showing no significant difference, with heterogeneity, I² = 66 %.</div></div><div><h3>Conclusions</h3><div>The review revealed no statistically significant difference between the two treatment modalities for managing irreversible pulpitis in primary teeth without clinical signs of swelling or radiographic evidence of periapical infection up to 12 months of follow-up. However, certainty of evidence was very low for both the outcomes.</div></div><div><h3>Clinical significance</h3><div>Pulpotomy appears to be an effective, minimally invasive alternative to pulpectomy in primary teeth with irreversible pulpitis. However, further well-designed, long-term studies are recommended.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"166 ","pages":"Article 106329"},"PeriodicalIF":5.5,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IF 5.5 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-01
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"164 ","pages":"Article 106249"},"PeriodicalIF":5.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146433444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IF 5.5 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-01
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"164 ","pages":"Article 106207"},"PeriodicalIF":5.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146433452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of dentistry
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1