Journal of Exotic Pet Medicine最新文献

英文中文

Corrigendum to “Sex and age-specific select hematologic and biochemical reference intervals for koi (Cyprinus rubrofuscus). Journal of Exotic Pet Medicine, Volume 54, June 2025, Pages 1-7.” 锦鲤性别和年龄特异性选择血液学和生化参考区间的勘误表。《奇异宠物医学杂志》，第54卷，2025年6月，第1-7页。

IF 0.6 4区农林科学 Q4 VETERINARY SCIENCES

Journal of Exotic Pet Medicine

Pub Date : 2026-01-01 Epub Date: 2026-01-06 DOI: 10.1053/j.jepm.2025.12.001

Alexandra T. Troiano , Melanie Ammersbach , Kelsey D. Brust , Kathryn L. Philips , Hugues Beaufrère , Esteban Soto

引用次数: 0

Feasibility of dental and oral cavity examination and dental radiography in sedated four-toed hedgehogs (Atelerix albiventris) 镇静四趾刺猬口腔及口腔检查及牙科x线摄影的可行性

IF 0.6 4区农林科学 Q4 VETERINARY SCIENCES

Journal of Exotic Pet Medicine

Pub Date : 2026-01-01 Epub Date: 2025-11-20 DOI: 10.1053/j.jepm.2025.11.001

Grayson A. Doss, Youna Jeon, Christopher Snyder

Objective

Report normal oral and dental examination findings and evaluate the feasibility of intraoral radiography in four-toed hedgehogs (Atelerix albiventris) under sedation.

Methods

Twelve healthy, adult hedgehogs (seven males, five females) were sedated with a combination of alfaxalone (5 mg/kg [2.3 mg/lb]) and midazolam (1 mg/kg [0.45 mg/lb]) SC and an oral examination performed in a research setting. The dental formula, documentation of calculus, missing teeth, fractures, mobility, and microdontia were recorded. Periodontal probing evaluating the sulcus depth for each tooth was performed and a gingivitis score assigned, if applicable. Dental radiography was performed using commercial phosphor dental imaging plates. Intraoral radiographs of maxillary and mandibular quadrants as well as skull radiographs were collected.

Results

Sedation was sufficient for performing most of the oral examination, except inspection of the tonsils, soft palate, and pharynx, and permitted intraoral radiography in all hedgehogs. The dental formula for each hedgehog varied, but most animals (7/12, 58%) had I 3/2, C 1/1, P 3/2, M 3/3. Most animals (9/12, 75%) had dental abnormalities, which were most noted in the maxillary quadrants (9/12, 75%). The most noted oral abnormality was calculi, seen in 7/12 (58%) animals. Gingivitis was present in 5/12 (42%) hedgehogs and was most associated with the maxillary incisors.

Conclusions and clinical relevance

Subcutaneous alfaxalone-midazolam provides adequate sedation for dental evaluation and intraoral radiography in four-toed hedgehogs. Calculus accumulation, missing teeth, and periodontal disease were common findings in this group of hedgehogs. The high rate of dental abnormalities found in this study underscores the importance of performing regular oral examinations using chemical immobilization in pet hedgehogs. Intraoral radiography can be used as in other pet species to guide clinical decision making.

目的报告四趾刺猬（Atelerix albiventris）在镇静状态下正常口腔和口腔检查结果，并评价口腔内x线摄影的可行性。方法12只健康成年刺猬（雄性7只，雌性5只）在研究环境中使用阿法沙龙（5mg /kg [2.3 mg/lb]）和咪达唑仑（1mg /kg [0.45 mg/lb]） SC联合镇静，并进行口腔检查。记录牙齿配方、牙石、缺牙、骨折、活动度和小牙。进行牙周探查，评估每颗牙齿的牙沟深度，并在适用的情况下进行牙龈炎评分。使用商用磷光体牙科成像板进行牙科x线摄影。收集上颌、下颌象限口内x线片及颅骨x线片。结果除扁桃体、软腭和咽部检查外，所有刺猬均可在镇静状态下进行大部分口腔检查，并允许进行口内x线摄影。每种刺猬的牙齿配方各不相同，但大多数动物（7/ 12,58%）的牙齿配方为I 3/2， C 1/1, P 3/2, M 3/3。大多数动物（9/12,75%）有牙齿异常，其中上颌象限最明显（9/12,75%）。最明显的口腔异常是结石，在7/12（58%）的动物中可见。5/12（42%）的刺猬存在牙龈炎，且与上颌门牙最相关。结论及临床意义皮下注射阿法沙隆-咪达唑仑可为四趾刺猬提供足够的镇静作用，用于牙科评估和口内x线摄影。在这组刺猬中，结石堆积、牙齿缺失和牙周病是常见的发现。本研究中发现的高牙齿异常率强调了在宠物刺猬中使用化学固定进行定期口腔检查的重要性。口内x线摄影可以像其他宠物一样用于指导临床决策。

{"title":"Feasibility of dental and oral cavity examination and dental radiography in sedated four-toed hedgehogs (Atelerix albiventris)","authors":"Grayson A. Doss, Youna Jeon, Christopher Snyder","doi":"10.1053/j.jepm.2025.11.001","DOIUrl":"10.1053/j.jepm.2025.11.001","url":null,"abstract":"<div><h3>Objective</h3><div>Report normal oral and dental examination findings and evaluate the feasibility of intraoral radiography in four-toed hedgehogs (<em>Atelerix albiventris</em>) under sedation.</div></div><div><h3>Methods</h3><div>Twelve healthy, adult hedgehogs (seven males, five females) were sedated with a combination of alfaxalone (5 mg/kg [2.3 mg/lb]) and midazolam (1 mg/kg [0.45 mg/lb]) SC and an oral examination performed in a research setting. The dental formula, documentation of calculus, missing teeth, fractures, mobility, and microdontia were recorded. Periodontal probing evaluating the sulcus depth for each tooth was performed and a gingivitis score assigned, if applicable. Dental radiography was performed using commercial phosphor dental imaging plates. Intraoral radiographs of maxillary and mandibular quadrants as well as skull radiographs were collected.</div></div><div><h3>Results</h3><div>Sedation was sufficient for performing most of the oral examination, except inspection of the tonsils, soft palate, and pharynx, and permitted intraoral radiography in all hedgehogs. The dental formula for each hedgehog varied, but most animals (7/12, 58%) had I 3/2, C 1/1, P 3/2, M 3/3. Most animals (9/12, 75%) had dental abnormalities, which were most noted in the maxillary quadrants (9/12, 75%). The most noted oral abnormality was calculi, seen in 7/12 (58%) animals. Gingivitis was present in 5/12 (42%) hedgehogs and was most associated with the maxillary incisors.</div></div><div><h3>Conclusions and clinical relevance</h3><div>Subcutaneous alfaxalone-midazolam provides adequate sedation for dental evaluation and intraoral radiography in four-toed hedgehogs. Calculus accumulation, missing teeth, and periodontal disease were common findings in this group of hedgehogs. The high rate of dental abnormalities found in this study underscores the importance of performing regular oral examinations using chemical immobilization in pet hedgehogs. Intraoral radiography can be used as in other pet species to guide clinical decision making.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"56 ","pages":"Pages 1-7"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145771865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe eosinophilic ulcerative dermatitis in a domestic rabbit (Oryctolagus cuniculus) 家兔严重嗜酸性溃疡性皮炎1例

IF 0.6 4区农林科学 Q4 VETERINARY SCIENCES

Journal of Exotic Pet Medicine

Pub Date : 2026-01-01 Epub Date: 2025-12-19 DOI: 10.1053/j.jepm.2025.12.003

Maricela Mejia Dorantes , Guillaume St-Jean , Isabelle Langlois

Background

Eosinophilic dermatitis can occur in most species and is usually associated with underlying hypersensitivity (such as allergies) or infection (parasite, bacteria, fungus). Cutaneous eosinophilic lesions are infrequently reported in rabbits.

Case description

A 4-year-old spayed female domestic lionhead rabbit was initially presented for a rounded, alopecic and intensively pruritic skin lesion in the ventral neck region. Over the course of several months, the rabbit developed other lesions over the left shoulder and neck area. Histopathologic analysis confirmed a diagnosis of severe eosinophilic ulcerative dermatitis. Skin scrapings, fungal culture, complete blood count, plasma biochemical analysis, whole body radiographs, and fecal flotation were unremarkable. Secondary bacterial dermatitis developed on 1 occasion in association with a ventral neck lesion, which was successfully treated with antibiotics. The initial treatment plan consisted of short courses of oral prednisolone along with hydroxyzine. The lesions were reported to recur shortly after discontinuation of prednisolone. Maintenance protocol using oral cyclosporine (5–7 mg/kg q 24 hour) and amitriptyline (5 mg/rabbit q 24 hour) combination adequately controlled the lesions for 23 months.

Conclusions and case relevance

Ulcerative eosinophilic dermatitis should be included in the differential diagnosis of ulcerative skin lesions in rabbits. The present case provides clinical insights regarding the treatment of ulcerative eosinophilic dermatitis in a pet rabbit

嗜酸性粒细胞性皮炎可发生在大多数物种中，通常与潜在的超敏反应（如过敏）或感染（寄生虫、细菌、真菌）有关。皮肤嗜酸性粒细胞病变在家兔中很少报道。病例描述：一只4岁的雌性家狮头兔，最初因颈部腹部出现圆形、脱发和强烈瘙痒的皮肤病变而就诊。在几个月的过程中，兔子在左肩和颈部出现了其他病变。组织病理学分析证实诊断为严重嗜酸性溃疡性皮炎。皮肤刮擦、真菌培养、全血细胞计数、血浆生化分析、全身x线片和粪便浮选无显著差异。继发性细菌性皮炎1次发展与腹侧颈部病变，这是成功地用抗生素治疗。最初的治疗方案包括口服强的松龙和羟嗪的短期疗程。据报道，病变复发后不久停止泼尼松龙。维持方案采用口服环孢素（5 - 7mg /kg q 24小时）和阿米替林（5mg /kg q 24小时）联合用药，可有效控制病变23个月。结论：兔溃疡性皮肤病变的鉴别诊断应包括溃疡性嗜酸性皮炎。本病例提供临床见解关于治疗溃疡性嗜酸性皮炎在宠物兔

{"title":"Severe eosinophilic ulcerative dermatitis in a domestic rabbit (Oryctolagus cuniculus)","authors":"Maricela Mejia Dorantes , Guillaume St-Jean , Isabelle Langlois","doi":"10.1053/j.jepm.2025.12.003","DOIUrl":"10.1053/j.jepm.2025.12.003","url":null,"abstract":"<div><h3>Background</h3><div>Eosinophilic dermatitis can occur in most species and is usually associated with underlying hypersensitivity (such as allergies) or infection (parasite, bacteria, fungus). Cutaneous eosinophilic lesions are infrequently reported in rabbits.</div></div><div><h3>Case description</h3><div>A 4-year-old spayed female domestic lionhead rabbit was initially presented for a rounded, alopecic and intensively pruritic skin lesion in the ventral neck region. Over the course of several months, the rabbit developed other lesions over the left shoulder and neck area. Histopathologic analysis confirmed a diagnosis of severe eosinophilic ulcerative dermatitis. Skin scrapings, fungal culture, complete blood count, plasma biochemical analysis, whole body radiographs, and fecal flotation were unremarkable. Secondary bacterial dermatitis developed on 1 occasion in association with a ventral neck lesion, which was successfully treated with antibiotics. The initial treatment plan consisted of short courses of oral prednisolone along with hydroxyzine. The lesions were reported to recur shortly after discontinuation of prednisolone. Maintenance protocol using oral cyclosporine (5–7 mg/kg q 24 hour) and amitriptyline (5 mg/rabbit q 24 hour) combination adequately controlled the lesions for 23 months.</div></div><div><h3>Conclusions and case relevance</h3><div>Ulcerative eosinophilic dermatitis should be included in the differential diagnosis of ulcerative skin lesions in rabbits. The present case provides clinical insights regarding the treatment of ulcerative eosinophilic dermatitis in a pet rabbit</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"56 ","pages":"Pages 36-38"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis and treatment of three leopard geckos (Eublepharis macularius) with hypovitaminosis A 3只斑豹壁虎维生素A缺乏症的诊断与治疗

IF 0.6 4区农林科学 Q4 VETERINARY SCIENCES

Journal of Exotic Pet Medicine

Pub Date : 2025-10-01 Epub Date: 2025-10-13 DOI: 10.1053/j.jepm.2025.10.001

Brandon J. Louth

Background

Definitive diagnosis of hypovitaminosis A is underperformed in reptiles with minimal understanding of effects of therapies beyond changes in clinical signs.

Materials and Methods

A retrospective review of medical records and plasma retinol diagnostics from a single private veterinary practice from 2023 to 2024, was performed. All leopard gecko (Eublepharis macularius) cases selected had presentation consistent with hypovitaminosis A, a CBC, biochemistry, fecal, plasma retinol evaluations, and monitored for at least 1 year. Three cases of leopard geckos met the selected criteria.

Results

Two cases showed leukocytosis. All cases had normal biochemistry values. All cases had negative fecal results. One case had a next-generation sequencing positive for Pseudomonas aeruginosa. Another had radiographic findings of a healed fracture in its tail. Initial plasma retinol values of all three cases were below the published reference range. After initial treatment values had increased to 0.11–0.24 µg/mL into reference range 2 days after initial injection. Plasma retinol values decreased 7 days after initial injection to 0.08–0.15 µg/mL. Values at 6 months for all cases were 0.22–0.26 µg/mL and at 1 year 0.21–0.24 µg/mL.

Conclusion and clinical relevance

These cases demonstrate the ability to diagnose, monitor, and treat vitamin A deficiency in leopard geckos. In these cases, an initial IM injection of 66,667 IU/kg of vitamin A followed by weekly injections of 10,000 IU/kg appeared to be safe and effective.

背景：爬行动物维生素A缺乏症的明确诊断不充分，除了临床症状的变化之外，对治疗效果的了解也很少。材料与方法回顾性分析某私人兽医诊所2023年至2024年的医疗记录和血浆视黄醇诊断结果。所有选择的豹壁虎（Eublepharis macularius）病例的表现与维生素缺乏症A一致，CBC，生化，粪便，血浆视黄醇评估，并监测至少1年。3例豹壁虎符合选定标准。结果2例出现白细胞增多。所有病例的生化指标均正常。所有病例大便结果均为阴性。1例铜绿假单胞菌下一代测序阳性。另一只的x线照片显示它的尾巴骨折愈合。三例患者的初始血浆视黄醇值均低于公布的参考范围。初始注射后2天，该数值增加到0.11-0.24µg/mL，进入参考范围。初始注射后7天血浆视黄醇值下降至0.08 ~ 0.15µg/mL。所有病例6个月时的数值为0.22-0.26µg/mL， 1年时为0.21-0.24µg/mL。结论与临床意义这些病例证明了豹壁虎维生素A缺乏症的诊断、监测和治疗能力。在这些病例中，最初注射66,667 IU/kg的维生素A，然后每周注射10,000 IU/kg的维生素A似乎是安全有效的。

{"title":"Diagnosis and treatment of three leopard geckos (Eublepharis macularius) with hypovitaminosis A","authors":"Brandon J. Louth","doi":"10.1053/j.jepm.2025.10.001","DOIUrl":"10.1053/j.jepm.2025.10.001","url":null,"abstract":"<div><h3>Background</h3><div>Definitive diagnosis of hypovitaminosis A is underperformed in reptiles with minimal understanding of effects of therapies beyond changes in clinical signs.</div></div><div><h3>Materials and Methods</h3><div>A retrospective review of medical records and plasma retinol diagnostics from a single private veterinary practice from 2023 to 2024, was performed. All leopard gecko (<em>Eublepharis macularius</em>) cases selected had presentation consistent with hypovitaminosis A, a CBC, biochemistry, fecal, plasma retinol evaluations, and monitored for at least 1 year. Three cases of leopard geckos met the selected criteria.</div></div><div><h3>Results</h3><div>Two cases showed leukocytosis. All cases had normal biochemistry values. All cases had negative fecal results. One case had a next-generation sequencing positive for <em>Pseudomonas aeruginosa</em>. Another had radiographic findings of a healed fracture in its tail. Initial plasma retinol values of all three cases were below the published reference range. After initial treatment values had increased to 0.11–0.24 µg/mL into reference range 2 days after initial injection. Plasma retinol values decreased 7 days after initial injection to 0.08–0.15 µg/mL. Values at 6 months for all cases were 0.22–0.26 µg/mL and at 1 year 0.21–0.24 µg/mL.</div></div><div><h3>Conclusion and clinical relevance</h3><div>These cases demonstrate the ability to diagnose, monitor, and treat vitamin A deficiency in leopard geckos. In these cases, an initial IM injection of 66,667 IU/kg of vitamin A followed by weekly injections of 10,000 IU/kg appeared to be safe and effective.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"55 ","pages":"Pages 34-39"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AEMV 4Q Newsletter 2025 AEMV第四季度通讯2025

IF 0.6 4区农林科学 Q4 VETERINARY SCIENCES

Journal of Exotic Pet Medicine

Pub Date : 2025-10-01 Epub Date: 2025-12-09 DOI: 10.1053/S1557-5063(25)00107-7

引用次数: 0

Avian & Exotic News 鸟类与异域新闻

IF 0.6 4区农林科学 Q4 VETERINARY SCIENCES

Journal of Exotic Pet Medicine

Pub Date : 2025-10-01 Epub Date: 2025-10-24 DOI: 10.1053/j.jepm.2025.09.004

引用次数: 0

EAAV 3Q Newspage 2025 EAAV 3Q新闻2025

IF 0.6 4区农林科学 Q4 VETERINARY SCIENCES

Journal of Exotic Pet Medicine

Pub Date : 2025-10-01 Epub Date: 2025-12-09 DOI: 10.1053/S1557-5063(25)00111-9

引用次数: 0

Glossitis in four-toed hedgehogs (Atelerix albiventris): 7 cases (2003–2023) 四趾刺猬舌炎7例（2003-2023）

IF 0.6 4区农林科学 Q4 VETERINARY SCIENCES

Journal of Exotic Pet Medicine

Pub Date : 2025-10-01 Epub Date: 2025-08-08 DOI: 10.1053/j.jepm.2025.08.001

Emma Pray , Gretel Tovar-Lopez , Audrey Kastner , Sarah Ozawa , Allison Watson , Anastasia Towe , Miranda J. Sadar

Background

Oral masses are a common finding in four-toed hedgehogs (Atelerix albiventris) under human care and are often diagnosed as neoplastic. Benign oral disease has also been reported, including inflammatory lesions of the oral mucosa and gingival hyperplasia. This retrospective study aimed to investigate cases of glossitis in hedgehogs, including signalment, clinical presentation, treatment protocol, and response to treatment.

Methods

Data was collected from three institutions over a 20-year period (October 2003–2023).

Results

A total of 1540 hedgehogs were evaluated during this time frame from all institutions and seven were identified with glossitis (overall prevalence 0.005%). Ages ranged from six months to five years (median 2.27 years), with five male intact, one male castrated, and one female intact animal. Most cases were treated on an emergency basis (6/7, 85.7%), with the most common presenting complaint being oral hemorrhage (5/7, 71.4%). Six cases (85.7%) were either grossly or histopathologically necrotic. Of the five with biopsies performed, all had acute suppurative glossitis, and two had a combination of acute and chronic disease. Treatment protocols with antibiotics and meloxicam were used in 6/7 cases (85.7%), and 4/7 (57.1%) achieved recorded or presumed resolution of clinical signs in two to twelve weeks.

Conclusions

While oral hemorrhage and swelling of the tongue are commonly associated with oral neoplasia in hedgehogs, glossitis with a more favorable outcome should also be included as a differential diagnosis and ruled out with ancillary testing.

背景：在人类照料的四趾刺猬（Atelerix albiventris）中，口部肿块是一种常见的发现，通常被诊断为肿瘤。良性口腔疾病也有报道，包括口腔黏膜炎性病变和牙龈增生。本回顾性研究旨在调查刺猬舌炎的病例，包括信号，临床表现，治疗方案和治疗反应。方法从三个机构收集数据，时间跨度为20年（2003年10月- 2023年10月）。结果在这段时间内，所有机构共评估了1540只刺猬，其中7只被鉴定为舌炎（总患病率为0.005%）。年龄范围从6个月到5岁（中位2.27岁），5只雄性完整，1只雄性阉割，1只雌性完整。大多数病例是急诊（6/7,85.7%），最常见的主诉是口腔出血（5/7,71.4%）。6例（85.7%）为严重或组织病理学坏死。在进行活组织检查的5例患者中，所有患者都患有急性化脓性舌炎，其中2例患有急慢性疾病。6/7例（85.7%）使用抗生素和美洛昔康治疗方案，4/7例（57.1%）在2至12周内达到记录或推定的临床症状缓解。结论：虽然口腔出血和舌头肿胀通常与刺猬的口腔肿瘤有关，但结果更有利的舌炎也应作为鉴别诊断，并通过辅助检查排除。

{"title":"Glossitis in four-toed hedgehogs (Atelerix albiventris): 7 cases (2003–2023)","authors":"Emma Pray , Gretel Tovar-Lopez , Audrey Kastner , Sarah Ozawa , Allison Watson , Anastasia Towe , Miranda J. Sadar","doi":"10.1053/j.jepm.2025.08.001","DOIUrl":"10.1053/j.jepm.2025.08.001","url":null,"abstract":"<div><h3>Background</h3><div>Oral masses are a common finding in four-toed hedgehogs (<em>Atelerix albiventris</em>) under human care and are often diagnosed as neoplastic. Benign oral disease has also been reported, including inflammatory lesions of the oral mucosa and gingival hyperplasia. This retrospective study aimed to investigate cases of glossitis in hedgehogs, including signalment, clinical presentation, treatment protocol, and response to treatment.</div></div><div><h3>Methods</h3><div>Data was collected from three institutions over a 20-year period (October 2003–2023).</div></div><div><h3>Results</h3><div>A total of 1540 hedgehogs were evaluated during this time frame from all institutions and seven were identified with glossitis (overall prevalence 0.005%). Ages ranged from six months to five years (median 2.27 years), with five male intact, one male castrated, and one female intact animal. Most cases were treated on an emergency basis (6/7, 85.7%), with the most common presenting complaint being oral hemorrhage (5/7, 71.4%). Six cases (85.7%) were either grossly or histopathologically necrotic. Of the five with biopsies performed, all had acute suppurative glossitis, and two had a combination of acute and chronic disease. Treatment protocols with antibiotics and meloxicam were used in 6/7 cases (85.7%), and 4/7 (57.1%) achieved recorded or presumed resolution of clinical signs in two to twelve weeks.</div></div><div><h3>Conclusions</h3><div>While oral hemorrhage and swelling of the tongue are commonly associated with oral neoplasia in hedgehogs, glossitis with a more favorable outcome should also be included as a differential diagnosis and ruled out with ancillary testing.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"55 ","pages":"Pages 4-8"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cheilitis secondary to infection with Acinetobacter baumannii in a pet rabbit 宠物兔感染鲍曼不动杆菌继发感染性溃疡

IF 0.6 4区农林科学 Q4 VETERINARY SCIENCES

Journal of Exotic Pet Medicine

Pub Date : 2025-10-01 Epub Date: 2025-09-08 DOI: 10.1053/j.jepm.2025.09.002

Teja Rosa , David Guillier

引用次数: 0

Surgical treatment with adjunctive metronomic chemotherapy of a prostatic adenocarcinoma in a rabbit (Oryctolagus cuniculus) 兔前列腺腺癌的手术治疗及辅助节律化疗

IF 0.6 4区农林科学 Q4 VETERINARY SCIENCES

Journal of Exotic Pet Medicine

Pub Date : 2025-10-01 Epub Date: 2025-09-24 DOI: 10.1053/j.jepm.2025.09.018

Aurélien Castellier , Chloé Vinomack , Anne Girard-Luc , Véronique Mentré

Background

Surgical and medical management of prostatic adenocarcinoma in rabbits are not well documented in the literature.

Case description

An 8-year-old intact male dwarf rabbit was presented for intermittent hematuria confirmed with urinalysis (urine strips). The rabbit showed mild pain on caudal abdominal palpation. A heterogeneous mass attached to the distal bladder and the proximal urethra was identified on abdominal radiographs and ultrasonography as well as some mild urine sludge suggestive of hypercalciuria. Ultrasound-guided fine needle aspirations were submitted for bacterial culture and cytology. Culture was negative and cytology was compatible with a proliferation of prostatic epithelial cells. Exploratory laparotomy allowed identification of the prostatic mass adherent to the distal bladder on its dorsal aspect. Partial surgical excision was performed and the mass was sent for pathology which was compatible with a prostatic adenocarcinoma. Recovery was uneventful except for a small caudal abdominal hernia repaired surgically 2 weeks later. The absence of visible extension of the tumor and potential metastatic process was evaluated and confirmed with CT-scan one month after surgery. Metronomic chemotherapy with oral cyclophosphamide 15mg/m² and meloxicam 0.6mg/kg q48h was implemented as adjuvant therapy for 12 months and no signs of recurrence or metastasis were observed after the 12 months of follow-up.

Conclusion and case relevance

This case reports a surgical treatment with adjunctive metronomic chemotherapy of a prostatic adenocarcinoma in a rabbit. Cyclophosphamide in conjunction with meloxicam was well tolerated and without adverse effects and should be considered as adjunctive therapy when incomplete surgical resection is suspected.

背景：家兔前列腺癌的外科和内科治疗在文献中没有很好的记录。病例描述：一只8岁的完整雄性矮兔因间歇性血尿经尿液分析（尿条）证实。家兔尾部腹部触诊有轻度疼痛。腹部x线片和超声检查发现膀胱远端和尿道近端有异质肿块，并发现轻度尿泥，提示高钙尿。超声引导下的细针穿刺进行细菌培养和细胞学检查。培养阴性，细胞学与前列腺上皮细胞增殖一致。剖腹探查可以在远端膀胱背侧发现附着的前列腺肿块。部分手术切除，肿块送病理检查，符合前列腺腺癌。恢复顺利，除了2周后手术修复了一个小的腹尾疝。术后1个月，通过ct扫描评估并确认肿瘤无明显扩展和潜在转移过程。以口服环磷酰胺15mg/m²、美洛昔康0.6mg/kg q48h的节奏化疗辅助治疗12个月，随访12个月无复发转移迹象。结论与病例相关性：本病例报告一例兔前列腺癌的手术治疗与辅助节律化疗。环磷酰胺联合美洛昔康耐受性良好，无不良反应，当怀疑手术切除不完全时应考虑作为辅助治疗。

{"title":"Surgical treatment with adjunctive metronomic chemotherapy of a prostatic adenocarcinoma in a rabbit (Oryctolagus cuniculus)","authors":"Aurélien Castellier , Chloé Vinomack , Anne Girard-Luc , Véronique Mentré","doi":"10.1053/j.jepm.2025.09.018","DOIUrl":"10.1053/j.jepm.2025.09.018","url":null,"abstract":"<div><h3>Background</h3><div>Surgical and medical management of prostatic adenocarcinoma in rabbits are not well documented in the literature.</div></div><div><h3>Case description</h3><div>An 8-year-old intact male dwarf rabbit was presented for intermittent hematuria confirmed with urinalysis (urine strips). The rabbit showed mild pain on caudal abdominal palpation. A heterogeneous mass attached to the distal bladder and the proximal urethra was identified on abdominal radiographs and ultrasonography as well as some mild urine sludge suggestive of hypercalciuria. Ultrasound-guided fine needle aspirations were submitted for bacterial culture and cytology. Culture was negative and cytology was compatible with a proliferation of prostatic epithelial cells. Exploratory laparotomy allowed identification of the prostatic mass adherent to the distal bladder on its dorsal aspect. Partial surgical excision was performed and the mass was sent for pathology which was compatible with a prostatic adenocarcinoma. Recovery was uneventful except for a small caudal abdominal hernia repaired surgically 2 weeks later. The absence of visible extension of the tumor and potential metastatic process was evaluated and confirmed with CT-scan one month after surgery. Metronomic chemotherapy with oral cyclophosphamide 15mg/m² and meloxicam 0.6mg/kg q48h was implemented as adjuvant therapy for 12 months and no signs of recurrence or metastasis were observed after the 12 months of follow-up.</div></div><div><h3>Conclusion and case relevance</h3><div>This case reports a surgical treatment with adjunctive metronomic chemotherapy of a prostatic adenocarcinoma in a rabbit. Cyclophosphamide in conjunction with meloxicam was well tolerated and without adverse effects and should be considered as adjunctive therapy when incomplete surgical resection is suspected.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"55 ","pages":"Pages 11-18"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145361735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

首页上一页

下一页尾页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Journal of Exotic Pet Medicine

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀