Pub Date : 2025-10-01DOI: 10.1053/j.jepm.2025.09.002
Teja Rosa , David Guillier
{"title":"Cheilitis secondary to infection with Acinetobacter baumannii in a pet rabbit","authors":"Teja Rosa , David Guillier","doi":"10.1053/j.jepm.2025.09.002","DOIUrl":"10.1053/j.jepm.2025.09.002","url":null,"abstract":"","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"55 ","pages":"Pages 9-10"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgical and medical management of prostatic adenocarcinoma in rabbits are not well documented in the literature.
Case description
An 8-year-old intact male dwarf rabbit was presented for intermittent hematuria confirmed with urinalysis (urine strips). The rabbit showed mild pain on caudal abdominal palpation. A heterogeneous mass attached to the distal bladder and the proximal urethra was identified on abdominal radiographs and ultrasonography as well as some mild urine sludge suggestive of hypercalciuria. Ultrasound-guided fine needle aspirations were submitted for bacterial culture and cytology. Culture was negative and cytology was compatible with a proliferation of prostatic epithelial cells. Exploratory laparotomy allowed identification of the prostatic mass adherent to the distal bladder on its dorsal aspect. Partial surgical excision was performed and the mass was sent for pathology which was compatible with a prostatic adenocarcinoma. Recovery was uneventful except for a small caudal abdominal hernia repaired surgically 2 weeks later. The absence of visible extension of the tumor and potential metastatic process was evaluated and confirmed with CT-scan one month after surgery. Metronomic chemotherapy with oral cyclophosphamide 15mg/m² and meloxicam 0.6mg/kg q48h was implemented as adjuvant therapy for 12 months and no signs of recurrence or metastasis were observed after the 12 months of follow-up.
Conclusion and case relevance
This case reports a surgical treatment with adjunctive metronomic chemotherapy of a prostatic adenocarcinoma in a rabbit. Cyclophosphamide in conjunction with meloxicam was well tolerated and without adverse effects and should be considered as adjunctive therapy when incomplete surgical resection is suspected.
{"title":"Surgical treatment with adjunctive metronomic chemotherapy of a prostatic adenocarcinoma in a rabbit (Oryctolagus cuniculus)","authors":"Aurélien Castellier , Chloé Vinomack , Anne Girard-Luc , Véronique Mentré","doi":"10.1053/j.jepm.2025.09.018","DOIUrl":"10.1053/j.jepm.2025.09.018","url":null,"abstract":"<div><h3>Background</h3><div>Surgical and medical management of prostatic adenocarcinoma in rabbits are not well documented in the literature.</div></div><div><h3>Case description</h3><div>An 8-year-old intact male dwarf rabbit was presented for intermittent hematuria confirmed with urinalysis (urine strips). The rabbit showed mild pain on caudal abdominal palpation. A heterogeneous mass attached to the distal bladder and the proximal urethra was identified on abdominal radiographs and ultrasonography as well as some mild urine sludge suggestive of hypercalciuria. Ultrasound-guided fine needle aspirations were submitted for bacterial culture and cytology. Culture was negative and cytology was compatible with a proliferation of prostatic epithelial cells. Exploratory laparotomy allowed identification of the prostatic mass adherent to the distal bladder on its dorsal aspect. Partial surgical excision was performed and the mass was sent for pathology which was compatible with a prostatic adenocarcinoma. Recovery was uneventful except for a small caudal abdominal hernia repaired surgically 2 weeks later. The absence of visible extension of the tumor and potential metastatic process was evaluated and confirmed with CT-scan one month after surgery. Metronomic chemotherapy with oral cyclophosphamide 15mg/m² and meloxicam 0.6mg/kg q48h was implemented as adjuvant therapy for 12 months and no signs of recurrence or metastasis were observed after the 12 months of follow-up.</div></div><div><h3>Conclusion and case relevance</h3><div>This case reports a surgical treatment with adjunctive metronomic chemotherapy of a prostatic adenocarcinoma in a rabbit. Cyclophosphamide in conjunction with meloxicam was well tolerated and without adverse effects and should be considered as adjunctive therapy when incomplete surgical resection is suspected.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"55 ","pages":"Pages 11-18"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145361735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Performing routine diagnostic tests in ferrets can be challenging without sedation, and intramuscular injections may be problematic due to their limited muscle mass. This study aimed to achieve moderate sedation levels using subcutaneously administered combinations of opioids and midazolam in ferrets. The effects, quality, and duration of sedation, as well as the cardiovascular and respiratory effects of midazolam in combination with three different opioids, were also evaluated.
Methods
Twelve healthy adult ferrets were used in a randomized, blinded, crossover study. Three sedation protocols were evaluated: MM group with midazolam (0.5 mg/kg SC) and methadone (0.3 mg/kg SC), MB group with midazolam (0.5 mg/kg SC) and butorphanol (0.2 mg/kg SC) and MH group with midazolam (0.5 mg/kg SC) and hydromorphone (0.2 mg/kg SC). Sedation scores and vital parameters were recorded every five minutes.
Results
All 12 ferrets lost their righting reflex in the MB group and 11 out of 12 in the MH group. In the MM group, only 1 out of 12 lost his righting reflex, and for only 2 minutes. The median sedation duration (between loss and return of righting reflex) was 33.5 minutes (4–66) in the MH group and 42 minutes (36–72) in the MB group. MB group had a significantly shorter time to sternal recumbency, lateral recumbency and loss of righting reflex compared to MH group. The heart rate was significantly lower with MB when compared to MH, and MB induced significantly lower respiratory rates compared to both MH and MM. Retching and vomiting were observed in 84% of ferrets in the MH group, 42% in the MM group and 17% in the MB group.
Conclusion and clinical relevance
Subcutaneous administration of midazolam at 0.5 mg/kg in combination with either hydromorphone at 0.2 mg/kg or butorphanol at 0.2 mg/kg achieved moderate sedation. The combination of midazolam and butorphanol used in this study showed fewer side effects and variability in sedation duration, which may make it a more appropriate choice in a clinical setting.
{"title":"Comparison of three sedation protocols using midazolam and opioids in domestic ferrets (Mustela Putorius Furo)","authors":"Jessie Vandenbruggen , Barbara Ambros , Hugues Beaufrère , Isabelle Desprez","doi":"10.1053/j.jepm.2025.09.017","DOIUrl":"10.1053/j.jepm.2025.09.017","url":null,"abstract":"<div><h3>Background</h3><div>Performing routine diagnostic tests in ferrets can be challenging without sedation, and intramuscular injections may be problematic due to their limited muscle mass. This study aimed to achieve moderate sedation levels using subcutaneously administered combinations of opioids and midazolam in ferrets. The effects, quality, and duration of sedation, as well as the cardiovascular and respiratory effects of midazolam in combination with three different opioids, were also evaluated.</div></div><div><h3>Methods</h3><div>Twelve healthy adult ferrets were used in a randomized, blinded, crossover study. Three sedation protocols were evaluated: MM group with midazolam (0.5 mg/kg SC) and methadone (0.3 mg/kg SC), MB group with midazolam (0.5 mg/kg SC) and butorphanol (0.2 mg/kg SC) and MH group with midazolam (0.5 mg/kg SC) and hydromorphone (0.2 mg/kg SC). Sedation scores and vital parameters were recorded every five minutes.</div></div><div><h3>Results</h3><div>All 12 ferrets lost their righting reflex in the MB group and 11 out of 12 in the MH group. In the MM group, only 1 out of 12 lost his righting reflex, and for only 2 minutes. The median sedation duration (between loss and return of righting reflex) was 33.5 minutes (4–66) in the MH group and 42 minutes (36–72) in the MB group. MB group had a significantly shorter time to sternal recumbency, lateral recumbency and loss of righting reflex compared to MH group. The heart rate was significantly lower with MB when compared to MH, and MB induced significantly lower respiratory rates compared to both MH and MM. Retching and vomiting were observed in 84% of ferrets in the MH group, 42% in the MM group and 17% in the MB group.</div></div><div><h3>Conclusion and clinical relevance</h3><div>Subcutaneous administration of midazolam at 0.5 mg/kg in combination with either hydromorphone at 0.2 mg/kg or butorphanol at 0.2 mg/kg achieved moderate sedation. The combination of midazolam and butorphanol used in this study showed fewer side effects and variability in sedation duration, which may make it a more appropriate choice in a clinical setting.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"55 ","pages":"Pages 21-27"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145361533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01DOI: 10.1053/j.jepm.2025.09.001
Audrey Simonian, Giulianna Obeid, Lara Cusack
Background
This case report describes the diagnosis, medical management, and surgical correction of congenital entropion with secondary trichiasis, blepharitis, and conjunctivitis in a 3-month-old male Syrian hamster (Mesocricetus auratus).
Case description
The patient presented with chronic left ocular discharge and eyelid inflammation that persisted despite medical therapy, including topical and systemic antibiotics, anti-inflammatory medications, and environmental modifications. A sedated ocular examination confirmed entropion and trichiasis, which were deemed the primary causes of ongoing ocular irritation. Surgical intervention, utilizing a modified Hotz-Celsus technique, was performed to correct the anatomical defect. Postoperative recovery was uneventful, with resolution of clinical signs and no recurrence observed during follow-up.
Conclusions and case relevance
Based on the literature search described below, this is the first reported case of surgical entropion correction in a Syrian hamster. The case highlights the challenges of diagnosing and managing ophthalmic conditions in small rodents, including limitations in ophthalmic examination, the importance of husbandry modifications, and the risks associated with anesthesia in these species. This report underscores the feasibility of surgical intervention in hamsters when medical management fails and provides insights into the multifactorial etiology of ocular disease in this species. Further research is needed to evaluate long-term outcomes and refine treatment protocols for ophthalmic conditions in hamsters.
{"title":"Surgical correction of unilateral entropion in a Syrian hamster","authors":"Audrey Simonian, Giulianna Obeid, Lara Cusack","doi":"10.1053/j.jepm.2025.09.001","DOIUrl":"10.1053/j.jepm.2025.09.001","url":null,"abstract":"<div><h3>Background</h3><div>This case report describes the diagnosis, medical management, and surgical correction of congenital entropion with secondary trichiasis, blepharitis, and conjunctivitis in a 3-month-old male Syrian hamster (<em>Mesocricetus auratus</em>).</div></div><div><h3>Case description</h3><div>The patient presented with chronic left ocular discharge and eyelid inflammation that persisted despite medical therapy, including topical and systemic antibiotics, anti-inflammatory medications, and environmental modifications. A sedated ocular examination confirmed entropion and trichiasis, which were deemed the primary causes of ongoing ocular irritation. Surgical intervention, utilizing a modified Hotz-Celsus technique, was performed to correct the anatomical defect. Postoperative recovery was uneventful, with resolution of clinical signs and no recurrence observed during follow-up.</div></div><div><h3>Conclusions and case relevance</h3><div>Based on the literature search described below, this is the first reported case of surgical entropion correction in a Syrian hamster. The case highlights the challenges of diagnosing and managing ophthalmic conditions in small rodents, including limitations in ophthalmic examination, the importance of husbandry modifications, and the risks associated with anesthesia in these species. This report underscores the feasibility of surgical intervention in hamsters when medical management fails and provides insights into the multifactorial etiology of ocular disease in this species. Further research is needed to evaluate long-term outcomes and refine treatment protocols for ophthalmic conditions in hamsters.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"55 ","pages":"Pages 28-31"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145361718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-08DOI: 10.1053/j.jepm.2025.08.001
Emma Pray , Gretel Tovar-Lopez , Audrey Kastner , Sarah Ozawa , Allison Watson , Anastasia Towe , Miranda J. Sadar
Background
Oral masses are a common finding in four-toed hedgehogs (Atelerix albiventris) under human care and are often diagnosed as neoplastic. Benign oral disease has also been reported, including inflammatory lesions of the oral mucosa and gingival hyperplasia. This retrospective study aimed to investigate cases of glossitis in hedgehogs, including signalment, clinical presentation, treatment protocol, and response to treatment.
Methods
Data was collected from three institutions over a 20-year period (October 2003–2023).
Results
A total of 1540 hedgehogs were evaluated during this time frame from all institutions and seven were identified with glossitis (overall prevalence 0.005%). Ages ranged from six months to five years (median 2.27 years), with five male intact, one male castrated, and one female intact animal. Most cases were treated on an emergency basis (6/7, 85.7%), with the most common presenting complaint being oral hemorrhage (5/7, 71.4%). Six cases (85.7%) were either grossly or histopathologically necrotic. Of the five with biopsies performed, all had acute suppurative glossitis, and two had a combination of acute and chronic disease. Treatment protocols with antibiotics and meloxicam were used in 6/7 cases (85.7%), and 4/7 (57.1%) achieved recorded or presumed resolution of clinical signs in two to twelve weeks.
Conclusions
While oral hemorrhage and swelling of the tongue are commonly associated with oral neoplasia in hedgehogs, glossitis with a more favorable outcome should also be included as a differential diagnosis and ruled out with ancillary testing.
{"title":"Glossitis in four-toed hedgehogs (Atelerix albiventris): 7 cases (2003–2023)","authors":"Emma Pray , Gretel Tovar-Lopez , Audrey Kastner , Sarah Ozawa , Allison Watson , Anastasia Towe , Miranda J. Sadar","doi":"10.1053/j.jepm.2025.08.001","DOIUrl":"10.1053/j.jepm.2025.08.001","url":null,"abstract":"<div><h3>Background</h3><div>Oral masses are a common finding in four-toed hedgehogs (<em>Atelerix albiventris</em>) under human care and are often diagnosed as neoplastic. Benign oral disease has also been reported, including inflammatory lesions of the oral mucosa and gingival hyperplasia. This retrospective study aimed to investigate cases of glossitis in hedgehogs, including signalment, clinical presentation, treatment protocol, and response to treatment.</div></div><div><h3>Methods</h3><div>Data was collected from three institutions over a 20-year period (October 2003–2023).</div></div><div><h3>Results</h3><div>A total of 1540 hedgehogs were evaluated during this time frame from all institutions and seven were identified with glossitis (overall prevalence 0.005%). Ages ranged from six months to five years (median 2.27 years), with five male intact, one male castrated, and one female intact animal. Most cases were treated on an emergency basis (6/7, 85.7%), with the most common presenting complaint being oral hemorrhage (5/7, 71.4%). Six cases (85.7%) were either grossly or histopathologically necrotic. Of the five with biopsies performed, all had acute suppurative glossitis, and two had a combination of acute and chronic disease. Treatment protocols with antibiotics and meloxicam were used in 6/7 cases (85.7%), and 4/7 (57.1%) achieved recorded or presumed resolution of clinical signs in two to twelve weeks.</div></div><div><h3>Conclusions</h3><div>While oral hemorrhage and swelling of the tongue are commonly associated with oral neoplasia in hedgehogs, glossitis with a more favorable outcome should also be included as a differential diagnosis and ruled out with ancillary testing.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"55 ","pages":"Pages 4-8"},"PeriodicalIF":0.6,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-01DOI: 10.1053/j.jepm.2025.06.002
Lorelei D’Avolio
{"title":"Review of: Ballard B and Cheek R, editors. “Exotic animal medicine for the veterinary technician”, 4th edition. Wiley Blackwell Inc, 705p; 2024","authors":"Lorelei D’Avolio","doi":"10.1053/j.jepm.2025.06.002","DOIUrl":"10.1053/j.jepm.2025.06.002","url":null,"abstract":"","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"54 ","pages":"Pages 37-38"},"PeriodicalIF":0.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-01DOI: 10.1053/j.jepm.2025.07.005
Hannah J. Dadah , Michelle G. Hawkins , Andrea W. Munk , Jodi L. Westropp , Philip H. Kass , Hugues Beaufrère
Objective
To determine potential risk and protective factors for the development of clinical urolithiasis in pet guinea pigs.
Animals
Approximately 242 guinea pigs (Cavia porcellus).
Methods
Signalment, dietary and medical history were recorded from urolith submissions from affected guinea pigs. The controls were identified via an online survey from owners of nonclinical pet guinea pigs, and data was collected regarding signalment, past medical history and diet. Clinical urolithiasis is defined as animals having or had the presence of uroliths identified via imaging, surgery, or manual expulsion, and control subjects may include subclinical or asymptomatic cases. Diets for control and affected subjects were assessed for percentage of pellets, hay, fruits/vegetables, high-calcium dietary items and vitamin C offered. Models were constructed with the best fit evaluated using Hosmer-Lemeshow tests. The 2 predictive models used, %hay (PH) and %pellets (PP), could not be combined due to their collinear nature.
Results
Data from 70 affected and 172 control guinea pigs were included in the analyses. Guinea pigs ≥24 months had higher odds of developing urolithiasis (PH: OR = 30.74; 95% CI [6.26–150.9], P < 0.001; PP: OR = 19.23; 95% CI [4.64–79.65], P < 0.001). Animals ≥1300 grams were more protected against urolithiasis (PH: OR = 0.05; 95% CI [0.0042–0.48], P < 0.010; PP: OR = 0.05; 95% CI [0.0045–0.47], P < 0.009). Affected males were overrepresented (62.8%, 44/70). Diets higher in %hay (PH: OR = 0.94; 95% CI [0.91–0.97], P < 0.001) or greater variety of fruits/vegetables (>7 types) (PH: OR = 0.66; 95% CI [0.57–0.76], P < 0.001; PP: OR = 0.69; 95% CI [0.61–0.80], P < 0.001) were more protective; guinea pigs with diets higher in %pellets were more likely to develop urolithiasis (PP: OR = 1.05; 95% CI [1.02–1.09], P < 0.003). High moisture (>50%) food items, such as bell peppers, tomatoes and romaine lettuce were especially protective against the formation of uroliths.
Conclusions and clinical relevance
Age, body weight, sex and dietary factors are important considerations for the development of clinical urolithiasis in guinea pigs and should be considered when tailoring preventative strategies for guinea pigs.
目的探讨宠物豚鼠临床尿石症发生的潜在危险因素和保护因素。动物:大约242只豚鼠。方法记录感染豚鼠尿石的信号、饮食和病史。通过对非临床宠物豚鼠的主人进行在线调查,确定了对照组,并收集了有关信号、既往病史和饮食的数据。临床尿石症的定义是通过影像学、手术或人工排出术发现有或曾经存在尿石的动物,对照组可能包括亚临床或无症状病例。对对照组和受影响受试者的饮食进行了评估,包括颗粒、干草、水果/蔬菜、高钙饮食项目和维生素C的百分比。采用Hosmer-Lemeshow检验评估模型的最佳拟合。所使用的2个预测模型,%干草(PH)和%颗粒(PP),由于它们的共线性性质,不能组合。结果70只感染豚鼠和172只对照豚鼠的数据被纳入分析。≥24个月的豚鼠发生尿石症的几率更高(PH: OR = 30.74;95% CI [6.26-150.9], P <;0.001;Pp: or = 19.23;95% CI [4.64-79.65], P <;0.001)。≥1300克的动物更容易患尿石症(PH: OR = 0.05;95% CI [0.0042-0.48], P <;0.010;Pp: or = 0.05;95% CI [0.0045-0.47], P <;0.009)。男性患者比例过高(62.8%,44/70)。饲粮中干草含量较高(PH: OR = 0.94;95% CI [0.91-0.97], P <;0.001)或更多种类的水果/蔬菜(>;7种)(PH: or = 0.66;95% CI [0.57-0.76], P <;0.001;Pp: or = 0.69;95% CI [0.61-0.80], P <;0.001)保护作用更强;饲粮中颗粒含量较高的豚鼠更容易患尿石症(PP: OR = 1.05;95% CI [1.02-1.09], P <;0.003)。高水分(50%)的食物,如甜椒、西红柿和长叶莴苣,特别能防止尿石的形成。结论和临床相关性年龄、体重、性别和饮食因素是豚鼠临床尿石症发生的重要考虑因素,在制定豚鼠预防策略时应予以考虑。
{"title":"Risk and protective factors associated with clinical urolithiasis in pet guinea pigs (Cavia porcellus)","authors":"Hannah J. Dadah , Michelle G. Hawkins , Andrea W. Munk , Jodi L. Westropp , Philip H. Kass , Hugues Beaufrère","doi":"10.1053/j.jepm.2025.07.005","DOIUrl":"10.1053/j.jepm.2025.07.005","url":null,"abstract":"<div><h3>Objective</h3><div>To determine potential risk and protective factors for the development of clinical urolithiasis in pet guinea pigs.</div></div><div><h3>Animals</h3><div>Approximately 242 guinea pigs (<em>Cavia porcellus</em>).</div></div><div><h3>Methods</h3><div>Signalment, dietary and medical history were recorded from urolith submissions from affected guinea pigs. The controls were identified via an online survey from owners of nonclinical pet guinea pigs, and data was collected regarding signalment, past medical history and diet. Clinical urolithiasis is defined as animals having or had the presence of uroliths identified via imaging, surgery, or manual expulsion, and control subjects may include subclinical or asymptomatic cases. Diets for control and affected subjects were assessed for percentage of pellets, hay, fruits/vegetables, high-calcium dietary items and vitamin C offered. Models were constructed with the best fit evaluated using Hosmer-Lemeshow tests. The 2 predictive models used, %hay (PH) and %pellets (PP), could not be combined due to their collinear nature.</div></div><div><h3>Results</h3><div>Data from 70 affected and 172 control guinea pigs were included in the analyses. Guinea pigs ≥24 months had higher odds of developing urolithiasis (PH: OR = 30.74; 95% CI [6.26–150.9], <em>P</em> < 0.001; PP: OR = 19.23; 95% CI [4.64–79.65], <em>P</em> < 0.001). Animals ≥1300 grams were more protected against urolithiasis (PH: OR = 0.05; 95% CI [0.0042–0.48], <em>P</em> < 0.010; PP: OR = 0.05; 95% CI [0.0045–0.47], <em>P</em> < 0.009). Affected males were overrepresented (62.8%, 44/70). Diets higher in %hay (PH: OR = 0.94; 95% CI [0.91–0.97], <em>P</em> < 0.001) or greater variety of fruits/vegetables (>7 types) (PH: OR = 0.66; 95% CI [0.57–0.76], <em>P</em> < 0.001; PP: OR = 0.69; 95% CI [0.61–0.80], <em>P</em> < 0.001) were more protective; guinea pigs with diets higher in %pellets were more likely to develop urolithiasis (PP: OR = 1.05; 95% CI [1.02–1.09], <em>P</em> < 0.003). High moisture (>50%) food items, such as bell peppers, tomatoes and romaine lettuce were especially protective against the formation of uroliths.</div></div><div><h3>Conclusions and clinical relevance</h3><div>Age, body weight, sex and dietary factors are important considerations for the development of clinical urolithiasis in guinea pigs and should be considered when tailoring preventative strategies for guinea pigs.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"54 ","pages":"Pages 28-34"},"PeriodicalIF":0.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-01DOI: 10.1053/j.jepm.2025.07.006
Miguel Gallego-Agundez , Cristina Díaz-Berciano
{"title":"Veterinary spending patterns for pet rabbits in Spain","authors":"Miguel Gallego-Agundez , Cristina Díaz-Berciano","doi":"10.1053/j.jepm.2025.07.006","DOIUrl":"10.1053/j.jepm.2025.07.006","url":null,"abstract":"","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"54 ","pages":"Pages 43-44"},"PeriodicalIF":0.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}