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Blood and urinalysis measurements in ferrets with clinically suspected chronic kidney disease 临床怀疑患有慢性肾脏疾病的雪貂的血液和尿液分析测量
IF 0.5 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2025-04-01 DOI: 10.1053/j.jepm.2025.03.004
Péter Pazár , Judit Csöndes , Zsolt Abonyi-Tóth , Adrienn Kaba , Viktor Molnár , Nándor Balogh

Background

Chronic kidney disease (CKD) is probably underdiagnosed in ferrets. Laboratory data of ferrets with CKD are lacking and no staging or treatment guidelines are available in this species. The purpose of this study was to evaluate potential blood and urinary biomarkers beyond urea and creatinine in diagnosing CKD in ferrets.

Methods

A retrospective study using blood and urine results from ferret suspected of having clinical CKD as well as 60 clinically healthy pet ferrets in a private practice specializing in exotic animals was conducted. Selected variables related to renal function including red blood cell count, albumin, urea, creatinine, total calcium, inorganic phosphate (P), symmetric dimethylarginine (SDMA), urine specific gravity (USG) and urine protein creatinine ratio (UPC ratio) were compared to a clinically healthy population. Diagnostic performance of serum urea, creatinine and SDMA were evaluated using receiver operator characteristic (ROC) curves.

Results

Statistically significant differences were found between the results of the 2 groups for all variables except for P. Ferrets from both groups had lower serum creatinine (median 73 µmol/L; 0.82 mg/dL in the CKD and 40 µmol/L; 0.45 mg/dL in the healthy group) and SDMA (median 7.45 µg/dL in the CKD and 5.1 µg/dL in the healthy group) values than described in dogs and cats. Ferrets with suspected CKD exhibited lower USG (1018 ± 6.71) and higher UPC ratio (median 1.86) compared to healthy animals (1039 ± 12.67 and median 0.23). The diagnostic value of serum creatinine (AUC = 0.807) was higher than that of urea (AUC = 0.720) or of SDMA (AUC = 0.713) for detecting CKD based on ROC analysis.

Conclusions and clinical relevance

The use of species-specific reference intervals is mandatory to recognize mild changes in renal function in ferrets. Urinalysis, including the measurement of USG and UPC ratio, can facilitate the diagnosis of CKD and are recommended in all ferrets with suspected renal disease.
背景:慢性肾脏疾病(CKD)在雪貂中可能未被充分诊断。目前缺乏慢性肾病雪貂的实验室数据,也没有针对该物种的分期或治疗指南。本研究的目的是评估除尿素和肌酐外,雪貂CKD诊断中潜在的血液和尿液生物标志物。方法对60只临床健康宠物雪貂和疑似临床CKD雪貂的血液和尿液进行回顾性研究。选择与肾功能相关的变量,包括红细胞计数、白蛋白、尿素、肌酐、总钙、无机磷酸盐(P)、对称二甲基精氨酸(SDMA)、尿比重(USG)和尿蛋白肌酐比(UPC),与临床健康人群进行比较。采用ROC曲线评价血清尿素、肌酐和SDMA的诊断效能。结果两组除雪貂外,其他变量的结果均有统计学差异,两组雪貂血清肌酐均较低(中位数73µmol/L;CKD为0.82 mg/dL, 40µmol/L;(健康组为0.45 mg/dL)和SDMA (CKD中位数为7.45 μ g/dL,健康组为5.1 μ g/dL)值比狗和猫的描述值高。疑似CKD的雪貂USG值(1018±6.71)低于健康动物(1039±12.67,中位数0.23),UPC值(中位数1.86)高于健康动物(中位数0.23)。基于ROC分析,血清肌酐(AUC = 0.807)对CKD的诊断价值高于尿素(AUC = 0.720)或SDMA (AUC = 0.713)。结论和临床意义使用物种特异性参考区间是识别雪貂肾功能轻微变化的必要条件。尿液分析,包括USG和UPC比值的测定,有助于CKD的诊断,建议所有怀疑有肾脏疾病的雪貂都进行尿液分析。
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引用次数: 0
Granulosa cell tumor and pyometra in a fourteen-year-old chinchilla (Chinchilla lanigera) 14岁栗鼠颗粒细胞瘤及脓膜肿大
IF 0.5 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2025-04-01 DOI: 10.1053/j.jepm.2025.03.005
Anja Böttcher , Petra Wirth , Stefanie Eggert
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引用次数: 0
Influence of environmental temperatures on chemical restraint of Nile tilapia (Oreochromis niloticus) with propofol 环境温度对异丙酚对尼罗罗非鱼化学抑制作用的影响
IF 0.5 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2025-04-01 DOI: 10.1053/j.jepm.2025.03.006
Vitória Maciel Arôso Mendes, Kétlen Monique Hoch Barbosa, Dandara Franco Ferreira da Silva, Sofia Silva La Rocca de Freitas, Clarissa Machado de Carvalho, FernandaVitória Marinhoda Costa Santos, Dara Evely Vieira Da Costa, Rodrigo Diana Navarro, Líria QueirozLuz Hirano

Background

Fish are ectothermic animals, so the water temperature determines their body temperature and directly influences their metabolism. In the anesthetic context, this must be considered, since the action and metabolism of medications may suffer interference if the temperature is outside the zone considered optimal for the species. Therefore, due to the influence of environmental temperature on fish metabolism, this study aimed to evaluate its effect on chemical restraint of adult Nile tilapia by immersion in 0.8 mg/L propofol.

Methods

Fifty animals were randomly divided into 2 groups. In group 1 (G1), the water temperature was kept below 20° C, while in second group (G2), it was above 25° C. After a general evaluation of the animals and the measurement of baseline parameters of posture, swimming pattern, and respiratory rate (RR), the tilapias were transferred to an induction aquarium containing the anesthetic diluted in water, where they remained for 5 minutes. Subsequently, they were transferred to a towel support for 15 minutes and monitored for heart rate (HR), RR, and spontaneous movement. Following this, the animals were transferred to a recovery aquarium.

Results

Propofol maintained stable heart rates and promoted absence of spontaneous movement, as well as reduced opercular movement rates in all evaluated tilapias. Statistical differences were observed between G1 and G2 in the HR and RR, with less spontaneous movement in G1.

Conclusions and clinical relevance

In conclusion, water temperature modifies the anesthesia response in Nile tilapias, with more pronounced effects observed at lower temperatures.
鱼类是恒温动物,因此水温决定了它们的体温,并直接影响它们的新陈代谢。在麻醉环境中,必须考虑到这一点,因为如果温度超出该物种的最佳温度范围,药物的作用和代谢可能会受到干扰。因此,由于环境温度对鱼类代谢的影响,本研究旨在评价0.8 mg/L异丙酚浸泡对尼罗罗非鱼成虫的化学约束效果。方法50只动物随机分为2组。第一组(G1)水温保持在20℃以下,第二组(G2)水温保持在25℃以上。在对罗非鱼进行一般评估并测量姿势、游泳方式和呼吸频率(RR)的基线参数后,将罗非鱼转移到含有稀释麻醉水的诱导水族池中,在那里停留5分钟。随后,他们被转移到毛巾支持15分钟,并监测心率(HR), RR和自发运动。之后,这些动物被转移到一个康复水族馆。结果异丙酚维持罗非鱼心率稳定,促进自发运动缺失,并降低眼动率。G1组与G2组HR、RR有统计学差异,G1组自发性运动较少。结论及临床意义总之,水温改变尼罗罗非鱼的麻醉反应,在较低温度下观察到的效果更明显。
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引用次数: 0
AEMV 2Q Newsletter 2025 AEMV第二季度通讯2025
IF 0.5 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2025-04-01 DOI: 10.1053/S1557-5063(25)00043-6
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引用次数: 0
Avian & Exotic News 鸟类与异域新闻
IF 0.5 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2025-04-01 DOI: 10.1053/j.jepm.2025.03.001
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引用次数: 0
EAAV 2Q Newspage 2025 EAAV 2Q新闻2025
IF 0.5 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2025-04-01 DOI: 10.1053/S1557-5063(25)00044-8
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引用次数: 0
USE OF PROPOFOL ASSOCIATED WITH METHADONE AND LOCAL BLOCKADE WITH LIDOCAINE IN SIX SPECIMENS OF FRESHWATER STINGRAYS (Potamotrygon spp.) 异丙酚联合美沙酮和利多卡因局部阻断在6种淡水黄貂鱼标本中的应用
IF 0.5 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2025-03-27 DOI: 10.1053/j.jepm.2025.03.003
Sofia Silva La Rocca de Freitas , Isabella Santana Fanger , Suzana Akemi Tsuruta , Délcio Almeida Magalhães , Laura Castro Silva , Maria Estela Mendes da Silva , André Eduardo Schlemper (PhD Student) , Márcio de Barros Bandarra (Professor)
Fish are the most diverse group of vertebrates, and their main characteristic is their aquatic habitat, with primary respiration through gills and ectothermy. The Potamotrygonidae is a family of cartilaginous fish that includes freshwater rays from South America. As they are restricted to freshwater environments, they possess anatomic and physiological particularities that differentiate them from other elasmobranchs. Potamotrygon is the most diverse genus, and although they are not aggressive fish, stingrays of this genus have a retro-serrated barb covered by a venom-producing glandular epithelium. This work aims to report the anesthetic protocol for barb resection from stingrays of two species from the genus Potamotrygon. Six stingrays (Potamotrygon falkneri, n = 3; P. leopoldi, n = 3) were sent to the Veterinary Hospital of the Federal University of Uberlândia (HVET-UFU) for surgical removal of the barb. The anesthetic protocol consisted of premedication with methadone administered intramuscularly, induction with propofol in the spiracles and local blockade with lidocaine without vasoconstriction. Trans-anesthetic monitoring was performed regarding the animals' water temperature, respiratory rate, and heart rate. All animals had fully recovered from anesthesia within five minutes, and no complications were recorded. Although the anesthesiology of elasmobranch fishes is still uncertain due to the scarcity of experimental models, the launched protocol yielded satisfactory results for promoting relaxation, analgesia, and rapid recovery.
鱼类是最多样化的脊椎动物群体,它们的主要特征是它们的水生栖息地,通过鳃进行初级呼吸和变温。软骨鱼科是一科软骨鱼,包括来自南美洲的淡水鳐鱼。由于它们只生活在淡水环境中,因此它们具有解剖学和生理学上的特殊性,使它们与其他板鳃目动物区别开来。黄貂鱼是最多样化的属,虽然它们不是侵略性的鱼,但这种属的黄貂鱼有一个向后锯齿状的倒刺,上面覆盖着分泌毒液的腺上皮。本工作旨在报道两种黄貂鱼鱼刺切除的麻醉方案。六黄貂鱼(Potamotrygon falkneri, n = 3;P. leopoldi, n = 3)被送往印度联邦大学兽医医院(HVET-UFU)进行手术切除倒刺。麻醉方案包括肌内美沙酮预用药,异丙酚诱导气门,利多卡因局部阻断,无血管收缩。经麻醉监测动物的水温、呼吸频率和心率。所有动物在5分钟内完全从麻醉中恢复,无并发症记录。尽管由于缺乏实验模型,板鳃鱼的麻醉机理仍不确定,但启动的方案在促进松弛、镇痛和快速恢复方面取得了令人满意的结果。
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引用次数: 0
Conservative management of bilateral fracture of the rami of the mandible in a rabbit 兔双侧下颌骨支骨折的保守治疗
IF 0.5 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2025-02-26 DOI: 10.1053/j.jepm.2025.02.002
Dimitria Gomes, Sarah Slaughter, Christopher Tollefson, Nicola Di Girolamo
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引用次数: 0
Septic tarsal synovitis and arthritis in a domestic rabbit (Oryctolagus cuniculi) 家兔感染性跗滑膜炎及关节炎一例
IF 0.5 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2025-02-26 DOI: 10.1053/j.jepm.2025.02.004
Harriet Woodhall
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引用次数: 0
Gastric dilatation and volvulus in a domestic rabbit 家兔胃扩张与胃扭转
IF 0.5 4区 农林科学 Q4 VETERINARY SCIENCES Pub Date : 2025-02-24 DOI: 10.1053/j.jepm.2025.02.003
Meir M. Barak , Sophie Liberman , Gina Vecere , Shachar Malka , Sophie Dennison

Background

Gastric dilatation and volvulus (GDV) is a well-documented, life-threatening condition in dogs and guinea pigs; however, it is rarely reported in rabbits.

Case description

A 3-year-old female spayed rabbit presented with a recent history of decreased appetite, no drinking, and being quiet and reluctant to move. On physical examination, the rabbit demonstrated discomfort during abdominal palpation. Whole-body CT scan revealed a GDV with the stomach rotated around the mesenteric axis. An exploratory laparotomy was performed, and the stomach was found to be rotated 180 degrees clockwise (from a caudal view). The stomach was de-rotated and an incisional gastropexy was performed. The rabbit was discharged 3 days postoperatively. At recheck examination 14 days postoperatively the rabbit was reportedly doing well with normal appetite, defecation, and energy levels. However, six days later the rabbit acutely died at home, and necropsy was declined by the owner.

Conclusions and case relevance

This publication is the first reported case of GDV in a rabbit, in the peer-reviewed literature. GDV should be included as a differential diagnosis in sick rabbits presented with nonspecific signs of lethargy and reduced food intake, as demonstrated by this case. While these clinical signs are common in many rabbit conditions, overlooking GDV as a possibility could have severe consequences given its potentially fatal nature.
胃扩张和胃扭转(GDV)是犬和豚鼠的一种有案可查的危及生命的疾病;然而,在家兔中很少有报道。病例描述:一只3岁雌性绝育兔近期出现食欲下降、不饮水、安静且不愿移动的病史。体格检查时,家兔腹部触诊不适。全身CT扫描显示胃绕肠系膜轴旋转的GDV。行剖腹探查术,发现胃顺时针旋转180度(从尾侧观察)。胃去旋转并行切口胃固定术。术后3 d出院。术后14天复查,兔的食欲、排便和能量水平正常。然而,六天后,兔子在家中急性死亡,主人拒绝尸检。结论和病例相关性本出版物是同行评议文献中首次报道的兔GDV病例。如本病例所示,对于表现为非特异性嗜睡和食物摄入减少的病兔,应将GDV纳入鉴别诊断。虽然这些临床症状在许多兔子的情况下很常见,但鉴于其潜在的致命性质,忽视GDV的可能性可能会造成严重后果。
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引用次数: 0
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Journal of Exotic Pet Medicine
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