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A double lateral pedicle graft technique for palatal recession coverage on dental implants. 一种双侧蒂移植物技术用于种植体腭部凹陷覆盖。
Q2 Dentistry Pub Date : 2023-09-01 DOI: 10.4103/jisp.jisp_379_22
Mihir Raghavendra Kulkarni, Neel Bhalachandra Bhatavadekar, Swati Badrinarayan Setty, Purva Vijay Bakshi

Rough surfaces of dental implants, when exposed to the oral environment, are conducive to biofilm colonization and can predispose the affected implant to periimplantitis. Recession coverage using soft-tissue grafts is one of the treatment modalities used for the treatment of exposed implant threads. Recession coverage on the palatal aspect of maxillary implants is difficult due to the firm nature of the palatal mucosa and, consequently has not been widely documented in the literature. This case report documents a novel double-pedicle technique for palatal recession coverage on a dental implant. Two pedicle grafts were obtained from either side of the implant with the mucosal recession: a full-thickness lateral-pedicle graft from the distal aspect and a subepithelial connective tissue pedicle from the mesial aspect. The connective tissue pedicle was stabilized first on the area of mucosal recession and was then covered with the distal full-thickness lateral pedicle. Complete recession coverage was obtained, and the result was observed to be clinically stable after 18 months of follow-up. The technique demonstrated in this report can be a useful tool for the treatment of localized palatal recessions on dental implants.

当牙齿植入物暴露在口腔环境中时,粗糙的表面有利于生物膜定植,并使受影响的植入物易患种植周炎。使用软组织移植物的凹陷覆盖是用于治疗暴露的植入物线的治疗模式之一。由于腭粘膜的坚固性,上颌种植体腭侧的凹陷覆盖很困难,因此文献中没有广泛记录。本病例报告记录了一种新的双椎弓根技术,用于种植牙上的腭凹陷覆盖。从粘膜凹陷的植入物两侧获得两个椎弓根移植物:一个来自远端的全厚侧椎弓根移植物和一个来自近中端的上皮下结缔组织椎弓根移植物。结缔组织蒂首先稳定在粘膜退缩区域,然后用远端全厚侧蒂覆盖。获得了完全的衰退覆盖,并且在18个月的随访后观察到结果在临床上是稳定的。本报告中展示的技术可以成为治疗种植牙局部腭凹陷的有用工具。
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引用次数: 0
Effect of LASER photobiomodulation on the cell viabilities of periodontal ligament fibroblasts of older and younger individuals - An in vitro study. 激光光生物调制对老年人和年轻人牙周膜成纤维细胞活性的影响——一项体外研究。
Q2 Dentistry Pub Date : 2023-09-01 DOI: 10.4103/jisp.jisp_167_22
Aditi Singh, Soumya Bardvalli Gururaj, Shrinidhi Maji Shankar, Chethana Kunthur Chidambar, Kala Bhushan, Bharathi Poojary

Background and objectives: Fibroblasts form the major cell type of the periodontal ligament and most often studied for periodontal regeneration. The aim of the present study was to investigate the effects of photobiomodulation (PBM) on aged periodontal fibroblasts and compare the viability of periodontal fibroblasts of older and younger individuals.

Materials and methods: A total of 32 patients were divided into four groups: A, B, C, and D. Groups A and C and B and D comprised of extracted teeth of older (>60 year) and younger individuals (<25 year), respectively. Extracted teeth from Groups A and B received PBM, (diode laser, 660 nm, 100 mW at 4J) whereas Groups C and D did not. Tissue from extracted teeth of all groups was processed and cultured and subjected to 3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay to assess their viability.

Results: The difference between the groups in terms of viability was significant (P < 0.0001). The mean viability of A and B (PBM) was 1.04 and 1.19, respectively. The mean viability for C and D (non-PBM) was 0.95 and 0.85, respectively.

Conclusion: Older fibroblasts have lower viability than younger fibroblasts. PBM improves viability in both older and younger fibroblasts and more so in younger fibroblasts. However, more than one PBM would be required to sustain the effect longer.

背景和目的:成纤维细胞是牙周膜的主要细胞类型,最常被研究用于牙周再生。本研究的目的是研究光生物调制(PBM)对老年牙周成纤维细胞的影响,并比较老年人和年轻人牙周成细胞的生存能力。材料和方法:共有32名患者被分为四组:A、B、C和D。A组、C组、B组和D组由年龄较大(>60岁)和较年轻的人的拔除牙齿组成(结果:两组在生存能力方面的差异非常显著(P<0.0001)。A组和B组(PBM)的平均生存能力分别为1.04和1.19。C和D(非PBM)的平均生存能力分别为0.95和0.85。结论:老年成纤维细胞的生存能力低于年轻成纤维细胞。PBM提高了老年和年轻成纤维细胞的生存能力,尤其是年轻成纤维纤维细胞。然而,需要一个以上的PBM才能维持更长的效果。
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引用次数: 0
Indian contributions to dental research. 印度人对牙科研究的贡献。
Q2 Dentistry Pub Date : 2023-09-01 DOI: 10.4103/jisp.jisp_318_23
Abhay P Kolte
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引用次数: 0
Evidence-based suggestions to improve the methodological issues in reporting of prevalence studies on gingival recession. 基于证据的建议,以改进牙龈退缩患病率研究报告中的方法学问题。
Q2 Dentistry Pub Date : 2023-09-01 DOI: 10.4103/jisp.jisp_400_22
Vikender Singh Yadav, Nitika Monga, Nisha K Jose, Harsh Priya

Gingival recession (GR) is considered a public health problem which is highly prevalent across different populations. Accuracy of psychometric properties of prevalence estimates of GR reported in epidemiological studies is important to facilitate setting public health goals, planning of public health programs, implementation of best practices and thereby developing public health policy. However, the reported prevalence estimates are influenced by the methodological variations among different studies, as observed in our recently published systematic review and meta-analysis on the global prevalence of GR. It substantially limits the comparability between studies and inferences about the true global variation in the prevalence of GR are difficult to establish. To address these issues, this commentary suggests to follow the standardized principles related to study design, clinical examination protocol, and characteristics of study subjects in future epidemiological studies on prevalence estimates of GR. Furthermore, the inclusion of additional domains in the reporting data is suggested for a deeper insight into the patterns of GR in different populations. Our suggestions are derived from a pragmatic approach and their consistent implementation would improve the reporting quality and achieve uniformity in future studies, thus benefitting the research in this area.

牙龈衰退(GR)被认为是一个在不同人群中高度流行的公共卫生问题。流行病学研究中报告的GR患病率估计的心理测量特性的准确性对于制定公共卫生目标、规划公共卫生计划、实施最佳实践以及制定公共卫生政策非常重要。然而,正如我们最近发表的关于GR全球患病率的系统综述和荟萃分析中所观察到的那样,报告的患病率估计受到不同研究之间方法学差异的影响。这大大限制了研究之间的可比性,很难建立关于GR患病率真正全球变化的推断。为了解决这些问题,本评论建议在未来的GR流行率估计流行病学研究中遵循与研究设计、临床检查方案和研究对象特征相关的标准化原则。此外,建议在报告数据中包含额外的结构域,以更深入地了解不同人群中GR的模式。我们的建议来源于一种务实的方法,它们的一致实施将提高报告质量,并在未来的研究中实现一致性,从而有利于该领域的研究。
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引用次数: 0
Periodontal health status among chronic obstructive pulmonary disease with age- and gender-matched controls. 慢性阻塞性肺病患者的牙周健康状况与年龄和性别匹配的对照。
Q2 Dentistry Pub Date : 2023-09-01 DOI: 10.4103/jisp.jisp_479_22
Dantala Satyanarayana, Suhas Kulkarni, Dolar Doshi, Madupu Padma Reddy, Sana Khaled, Adepu Srilatha

Background: Periodontal disease and chronic obstructive pulmonary disease (COPD) share a pathogenic mechanism that involves activating and using inflammatory cytokines and neutrophils, which generate pathological changes in various tissues with a chronic degenerative outcome.

Aim: the aim of this study was to assess and compare the periodontal health status among COPD patients with age- and gender-matched controls.

Materials and methods: All the patients aged >30 years who were diagnosed with COPD by the physician were included as cases, while people who are apparently healthy and age and gender matched with cases were included as controls. Data on demographic details, socioeconomic status (Kuppuswamy scale), deleterious oral habits, and oral hygiene practices were obtained. The Simplified Oral Hygiene Index (OHI-S) and the WHO basic oral health survey proforma (1997) were used to obtain the data on oral hygiene and periodontal status respectively.

Results: Most cases had moderate COPD severity (58.25%). The overall mean OHI-S, CPI, and LOA were higher among cases (3.92 ± 0.95, 3.68 ± 0.60, and 2.33 ± 1.10, respectively) in comparison to controls. Further, among cases, the mean oral hygiene and periodontitis increased with increased severity of COPD. Although among both cases and controls, gender, tobacco use, and alcohol consumption influenced their periodontal status, significant odds of higher risk were seen only among cases. Further, subjects with COPD had higher odds of having poor oral hygiene, deeper pocket depths, and LOA.

Conclusion: A strong association between COPD and periodontitis was observed. The oral hygiene and periodontal disease worsened with the severity of COPD.

背景:牙周病和慢性阻塞性肺病(COPD)有一个共同的致病机制,涉及激活和使用炎性细胞因子和中性粒细胞,它们会在各种组织中产生病理变化,并导致慢性退行性变。目的:本研究的目的是评估和比较COPD患者与年龄和性别匹配的对照组的牙周健康状况。材料和方法:将所有30岁以上经医生诊断为COPD的患者作为病例,将明显健康且年龄和性别与病例匹配的人作为对照。获得了有关人口统计细节、社会经济地位(库普斯瓦米量表)、有害口腔习惯和口腔卫生习惯的数据。采用简化口腔卫生指数(OHI-S)和世界卫生组织基本口腔卫生调查表(1997),分别获得口腔卫生和牙周状况数据。结果:大多数病例具有中度COPD严重程度(58.25%)。与对照组相比,病例的总体平均OHI-S、CPI和LOA较高(分别为3.92±0.95、3.68±0.60和2.33±1.10)。此外,在病例中,平均口腔卫生和牙周炎随着COPD严重程度的增加而增加。尽管在病例和对照组中,性别、吸烟和饮酒都会影响他们的牙周状况,但只有在病例中才发现较高风险的显著几率。此外,患有COPD的受试者口腔卫生不良、袋深较深和LOA的几率较高。结论:COPD与牙周炎之间存在强烈的相关性。口腔卫生和牙周病随着COPD的严重程度而恶化。
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引用次数: 0
Adjunctive benefit of probiotic supplementation along with nonsurgical therapy for peri-implant diseases - A systematic review and meta-analysis. 益生菌补充与非手术治疗种植体周围疾病的辅助益处——一项系统综述和荟萃分析。
Q2 Dentistry Pub Date : 2023-07-01 DOI: 10.4103/jisp.jisp_308_22
R Ambili, Nias Bin Nazimudeen

Peri-implant diseases are prevalent conditions, but a predictable management strategy is still lacking. The objective of the present article was to evaluate the adjunctive benefits of probiotics with nonsurgical therapy in the management of peri-implant diseases. The review protocol was registered in PROSPERO and prepared according to PRISMA guidelines. Randomized controlled clinical trials in patients diagnosed with the peri-implant disease where probiotic was used as an adjunct to nonsurgical therapy were included in the study. The risk difference of percentage reduction in bleeding on probing, plaque accumulation, and mean difference in probing pocket depth reductions at implant level were estimated using a random effect model due to high heterogeneity among studies. Four studies fulfilled the criteria for selection. Two of them presented data on both peri-implantitis and peri-implant mucositis and they were considered separate studies during meta-analysis. Significant reduction in percentage of bleeding on probing was noticed at 1 and 3 months (-0.28 [-0.48, -0.09], P = 0.004 and - 0.19 [-0.35, -0.02], P = 0.03, respectively), but the reduction was not statistically significant at 6 months. Similar results were also observed for plaque accumulation. No statistically significant reduction in probing pocket depth was observed in the probiotic group during any of the re-evaluations.

Conclusion: Adjunctive therapy of probiotics may improve the efficacy of nonsurgical therapy of peri-implant diseases for up to 3 months. However, moderate certainty was observed for a reduction in bleeding on probing after 1-month re-evaluation alone.

种植体周围疾病普遍存在,但仍缺乏可预测的管理策略。本文的目的是评估益生菌与非手术治疗在种植体周围疾病管理中的辅助益处。审查方案已在PROSPERO注册,并根据PRISMA指南编制。该研究包括对被诊断为种植体周围疾病的患者进行的随机对照临床试验,其中益生菌被用作非手术治疗的辅助药物。由于研究之间的高度异质性,使用随机效应模型估计了探查出血减少百分比、斑块积聚的风险差异以及植入物水平探查袋深度减少的平均差异。四项研究符合入选标准。其中两人提供了种植体周围炎和种植体周围粘膜炎的数据,在荟萃分析中,他们被视为单独的研究。在1个月和3个月时,探查出血百分比显著降低(分别为-0.28[-0.48,-0.09],P=0.004和-0.19[-0.35,-0.02],P=0.03),但在6个月时出血百分比没有统计学意义。对于斑块积聚也观察到类似的结果。在任何重新评估期间,在益生菌组中均未观察到探测袋深度的统计学显著减少。结论:益生菌的辅助治疗可以提高种植体周围疾病的非手术治疗效果长达3个月。然而,在单独进行1个月的重新评估后,在探查时观察到出血减少的适度确定性。
{"title":"Adjunctive benefit of probiotic supplementation along with nonsurgical therapy for peri-implant diseases - A systematic review and meta-analysis.","authors":"R Ambili,&nbsp;Nias Bin Nazimudeen","doi":"10.4103/jisp.jisp_308_22","DOIUrl":"10.4103/jisp.jisp_308_22","url":null,"abstract":"<p><p>Peri-implant diseases are prevalent conditions, but a predictable management strategy is still lacking. The objective of the present article was to evaluate the adjunctive benefits of probiotics with nonsurgical therapy in the management of peri-implant diseases. The review protocol was registered in PROSPERO and prepared according to PRISMA guidelines. Randomized controlled clinical trials in patients diagnosed with the peri-implant disease where probiotic was used as an adjunct to nonsurgical therapy were included in the study. The risk difference of percentage reduction in bleeding on probing, plaque accumulation, and mean difference in probing pocket depth reductions at implant level were estimated using a random effect model due to high heterogeneity among studies. Four studies fulfilled the criteria for selection. Two of them presented data on both peri-implantitis and peri-implant mucositis and they were considered separate studies during meta-analysis. Significant reduction in percentage of bleeding on probing was noticed at 1 and 3 months (-0.28 [-0.48, -0.09], <i>P</i> = 0.004 and - 0.19 [-0.35, -0.02], <i>P</i> = 0.03, respectively), but the reduction was not statistically significant at 6 months. Similar results were also observed for plaque accumulation. No statistically significant reduction in probing pocket depth was observed in the probiotic group during any of the re-evaluations.</p><p><strong>Conclusion: </strong>Adjunctive therapy of probiotics may improve the efficacy of nonsurgical therapy of peri-implant diseases for up to 3 months. However, moderate certainty was observed for a reduction in bleeding on probing after 1-month re-evaluation alone.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 4","pages":"352-361"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10049992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Crestal sinus augmentation in a head back position: Retrospective case series. 头靠后位置的上颌窦扩大术:回顾性病例系列。
Q2 Dentistry Pub Date : 2023-07-01 DOI: 10.4103/jisp.jisp_229_22
Yuhang Zhang, Chunyuan Zhang

Objectives: To evaluate the clinical efficacy of Crestal Sinus Augmentation (CSA) in a head back position (CSA-HBP) for maxillary sinus mucosa elevation.

Materials and methods: We enrolled 209 patients, 246 maxillary sinuses, 348 sites in this study. Complications, maxillary sinus mucosal perforation rate and cumulative survival rate (CSR) data were collected to evaluate the clinical efficacy of CSA-HBP. Maxillary sinus mucosal elevation height (EH) and new bone height (NH) were measured by cone-beam computerized tomography and standard periapical radiographs. The implantation sites of residual bone height (RBH) ≤5 mm and RBH >5 mm were marked as Groups A (n = 81) and B (n = 267), respectively. The implantation sites of the second and third molar sites were marked as Group C (n = 134), and the remaining sites were marked as Group D (n = 214).

Results: The RBH before implant placement was 6.63 ± 2.10 mm (95% confidence interval [CI] 6.41- 6.85 mm). The mucosal EH was 4.04 ± 1.86 mm (95% CI 3.85 - 4.24 mm). The NH was 2.36 ± 1.20 mm (95% CI 3.85-4.24 mm). No other complications were found except three cases of postoperative swelling and one case of nasal blood secretions. The overall mucosal perforation rate was 1.44% (5/348, 95% CI 0.2%-2.7%) and the rate of RBH ≤ 5 mm (Group A) was 1.49% (2/134, 95% CI 0%-3.50%). The 8-year CSR was 99.71% (347/348, 95% CI 99.2%-100.0%). Mucosal EH and NH were higher in RBH ≤5 mm (Group A) than in RBH >5 mm (Group B) (P = 0.001 and P = 0.001, Mann-Whitney U-test). There were no significant differences in mucosal EH and perforation rate between second and third molar sites (Group C) and other sites (Group D) (P = 0.77, Mann-Whitney U-test, and P = 0.16, Yates' Chi-square independence test).

Conclusions: CSA-HBP is a minimally invasive and reliable technique.

目的:评价头后位上颌窦扩大术(CSA)治疗上颌窦粘膜抬高的临床疗效。材料和方法:本研究共纳入209例患者,246个上颌窦,348个部位。收集并发症、上颌窦粘膜穿孔率和累积生存率(CSR)数据,评价CSA-HBP的临床疗效。用锥束计算机断层扫描和标准根尖周x线片测量上颌窦粘膜抬高高度(EH)和新骨高度(NH)。将残余骨高(RBH)≤5mm和RBH>5mm的植入部位分别标记为A组(n=81)和B组(n=267)。结果:种植前RBH为6.63±2.10mm(95%可信区间[CI]6.41~6.85mm)。粘膜EH为4.04±1.86mm(95%可信区间3.85-4.24mm)。NH为2.36±1.20 mm(95%可信区间3.85-4.24 mm)。除3例术后肿胀和1例鼻腔分泌物外,未发现其他并发症。总粘膜穿孔率为1.44%(5/348,95%CI 0.2%-2.7%),RBH≤5 mm的发生率(A组)为1.49%(2/134,95%CI 0%-3.50%)。8年CSR为99.71%(347/348,95%CI 99.2%-100.0%)。第二和第三磨牙部位(C组)与其他部位(D组)的粘膜EH和穿孔率无显著差异(P=0.77,Mann-Whitney U检验,P=0.16,Yates卡方独立性检验)。结论:CSA-HBP是一种微创可靠的技术。
{"title":"Crestal sinus augmentation in a head back position: Retrospective case series.","authors":"Yuhang Zhang,&nbsp;Chunyuan Zhang","doi":"10.4103/jisp.jisp_229_22","DOIUrl":"10.4103/jisp.jisp_229_22","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the clinical efficacy of Crestal Sinus Augmentation (CSA) in a head back position (CSA-HBP) for maxillary sinus mucosa elevation.</p><p><strong>Materials and methods: </strong>We enrolled 209 patients, 246 maxillary sinuses, 348 sites in this study. Complications, maxillary sinus mucosal perforation rate and cumulative survival rate (CSR) data were collected to evaluate the clinical efficacy of CSA-HBP. Maxillary sinus mucosal elevation height (EH) and new bone height (NH) were measured by cone-beam computerized tomography and standard periapical radiographs. The implantation sites of residual bone height (RBH) ≤5 mm and RBH >5 mm were marked as Groups A (<i>n</i> = 81) and B (<i>n</i> = 267), respectively. The implantation sites of the second and third molar sites were marked as Group C (<i>n</i> = 134), and the remaining sites were marked as Group D (<i>n</i> = 214).</p><p><strong>Results: </strong>The RBH before implant placement was 6.63 ± 2.10 mm (95% confidence interval [CI] 6.41- 6.85 mm). The mucosal EH was 4.04 ± 1.86 mm (95% CI 3.85 - 4.24 mm). The NH was 2.36 ± 1.20 mm (95% CI 3.85-4.24 mm). No other complications were found except three cases of postoperative swelling and one case of nasal blood secretions. The overall mucosal perforation rate was 1.44% (5/348, 95% CI 0.2%-2.7%) and the rate of RBH ≤ 5 mm (Group A) was 1.49% (2/134, 95% CI 0%-3.50%). The 8-year CSR was 99.71% (347/348, 95% CI 99.2%-100.0%). Mucosal EH and NH were higher in RBH ≤5 mm (Group A) than in RBH >5 mm (Group B) (<i>P</i> = 0.001 and <i>P</i> = 0.001, Mann-Whitney <i>U</i>-test). There were no significant differences in mucosal EH and perforation rate between second and third molar sites (Group C) and other sites (Group D) (<i>P</i> = 0.77, Mann-Whitney <i>U</i>-test, and <i>P</i> = 0.16, Yates' Chi-square independence test).</p><p><strong>Conclusions: </strong>CSA-HBP is a minimally invasive and reliable technique.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 4","pages":"428-433"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10049995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paradental cyst with hyaline ring granuloma masquerading as pericoronitis. 冠旁囊肿伴透明环状肉芽肿,伪装为冠周炎。
Q2 Dentistry Pub Date : 2023-07-01 DOI: 10.4103/jisp.jisp_292_22
V Vasanthi, Tamizh Paavai Tha, A Ramesh Kumar, Sasikala Balasubramanian

Paradental cyst is an odontogenic cyst associated with pericoronitis in partly erupted mandibular third molars. It is an inflammatory cyst common among the mandibular molars. The cyst is most commonly seen on the distal or distobuccal aspect of the third molars. The angle of tooth and food impaction has been postulated to be responsible for the development of the cyst in third molars. The source of the epithelium has been reported as reduced enamel epithelium. The paradental cyst is frequently misdiagnosed as a radicular cyst or dentigerous cyst. We report a case of paradental cyst in a patient with partially erupted mandibular third molar with food impaction and resulting hyaline ring granuloma.

副囊肿是一种牙源性囊肿,与部分萌出的下颌第三磨牙冠周炎相关。它是一种常见于下颌磨牙的炎症性囊肿。囊肿最常见于第三磨牙的远端或双颊侧。牙齿和食物嵌塞的角度被认为是第三磨牙囊肿形成的原因。据报道,上皮的来源是减少的釉质上皮。齿旁囊肿常被误诊为根性囊肿或齿状囊肿。我们报告了一例下颌第三磨牙部分萌出并伴有食物嵌塞并导致透明环状肉芽肿的患者的牙列囊肿。
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引用次数: 1
Ethics in publication: Some life lessons. 出版伦理:一些人生教训。
Q2 Dentistry Pub Date : 2023-07-01 DOI: 10.4103/jisp.jisp_250_23
Harpreet Singh Grover
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引用次数: 0
In vitro evaluation of remineralizing agents on dentinal tubule occlusion: A scanning electron microscopic study. 再矿化剂对牙本质小管闭塞的体外评价:扫描电镜研究。
Q2 Dentistry Pub Date : 2023-07-01 DOI: 10.4103/jisp.jisp_413_22
Akanksha Kidiyur Sathish, Pratibha Gopalkrishna, Santhosh Kumar

Context: Over the years, numerous treatment modalities have been researched for the management of dentinal hypersensitivity. A recent remineralizing agent containing a phase of amorphous calcium phosphate combined with fluoride has shown the ability to rapidly convert into biomimetic hydroxyapatite. This potential can be utilized in occluding the dentinal tubules for the treatment of hypersensitivity.

Aims: The present study aims to compare the effectiveness of biomimetic hydroxyapatite-based tooth mousse and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) tooth mousse as desensitizing agents on dentinal tubule occlusion.

Materials and methods: The in vitro study design involved 30 prepared dentin specimens that were divided into three groups: Group A: negative control, Group B: CPP-ACP tooth mousse (GC tooth mousse), and Group C: fluoride-doped amorphous calcium phosphate (F-ACP) tooth mousse (Curasept Biosmalto Denti Sensibili Tooth Mousse). The specimens were observed under a scanning electron microscope (SEM) and an attached energy-dispersive X-ray (EDX) spectroscopy apparatus after 1 week.

Statistical analysis: The data were analyzed using Kruskal-Wallis test and post hoc Mann-Whitney test for intragroup and intergroup analysis, respectively.

Results: The SEM analysis of the F-ACP group showed statistically greater percentage of tubule occlusion (40.21%) compared to the CPP-ACP group (38.15%). EDX analysis of both F-ACP and CPP-ACP groups revealed calcium, phosphorus, carbon, oxygen, and silica with an additional fluoride element in the F-ACP group.

Conclusions: In the present study, both remineralizing agents were able to occlude the dentinal tubules. Among the two, the F-ACP tooth mousse showed greater tubule occlusion, and therefore, appears promising as an upcoming remineralizing agent in the management of dentinal hypersensitivity.

背景:多年来,已经研究了多种治疗方式来治疗牙本质过敏症。最近一种含有无定形磷酸钙与氟化物相结合的再矿化剂显示出快速转化为仿生羟基磷灰石的能力。这种潜力可用于堵塞牙本质小管,以治疗超敏反应。目的:本研究旨在比较仿生羟基磷灰石基牙胶和酪蛋白磷酸肽无定形磷酸钙(CPP-ACP)牙胶作为牙本质小管闭塞脱敏剂的疗效。材料和方法:体外研究设计涉及30个制备的牙本质标本,分为三组:A组:阴性对照,B组:CPP-ACP牙摩丝(GC牙摩丝™), C组:氟掺杂无定形磷酸钙(F-ACP)牙慕斯(Curasept Biosmalloto Denti Sensibili tooth mousse)。1周后,在扫描电子显微镜(SEM)和所附的能量色散X射线(EDX)光谱设备下观察样品。统计分析:分别使用Kruskal-Wallis检验和事后Mann-Whitney检验对数据进行组内和组间分析。结果:F-ACP组的SEM分析显示,与CPP-ACP组(38.15%)相比,F-ACP的小管闭塞百分比(40.21%)在统计学上更高。F-ACP和CPP-ACP两组的EDX分析均显示F-ACP中存在钙、磷、碳、氧和二氧化硅以及额外的氟元素。结论:在本研究中,两种再矿化剂都能堵塞牙本质小管。在这两者中,F-ACP牙摩丝表现出更大的小管堵塞,因此,作为一种即将出现的治疗牙本质过敏症的再矿化剂,似乎很有前景。
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引用次数: 0
期刊
Journal of Indian Society of Periodontology
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