Sara Salucci, Sabrina Burattini, Ilaria Versari, Alberto Bavelloni, Francesco Bavelloni, Davide Curzi, Michela Battistelli, Pietro Gobbi, Irene Faenza
Prolonged exposure to high dosages of dexamethasone, which is a synthetic glucocorticoid and a well-known anti-inflammatory drug, may lead to an increase in reactive oxygen species production, contributing to muscle wasting. The prevention of muscle atrophy by ingestion of functional foods is an attractive issue. In the last decade, natural antioxidant compounds have been increasingly investigated as promising molecules able to counteract oxidative-stress-induced muscle atrophy. Recently, we have demonstrated the antioxidant properties of two main olive oil polyphenols also known for their anticancer and anti-inflammatory activities in different cell models. Here, the preventive effect of tyrosol on dexamethasone-induced muscle atrophy has been investigated by means of morpho-functional approaches in C2C12 myotubes. Dexamethasone-treated cells showed a reduced fiber size when compared to control ones. While long and confluent myotubes could be observed in control samples, those exposed to dexamethasone appeared as immature syncytia. Dysfunctional mitochondria and the accumulation of autophagic vacuoles contributed to myotube degeneration and death. Tyrosol administration before glucocorticoid treatment prevented muscle wasting and rescued mitochondrial and lysosomal functionality. These findings demonstrate that tyrosol attenuates dexamethasone-induced myotube damage, and encourage the use of this natural molecule in preclinical and clinical studies and in synergy with other functional foods or physical activity with the aim to prevent muscle atrophy.
{"title":"Morpho-Functional Analyses Demonstrate That Tyrosol Rescues Dexamethasone-Induced Muscle Atrophy.","authors":"Sara Salucci, Sabrina Burattini, Ilaria Versari, Alberto Bavelloni, Francesco Bavelloni, Davide Curzi, Michela Battistelli, Pietro Gobbi, Irene Faenza","doi":"10.3390/jfmk9030124","DOIUrl":"10.3390/jfmk9030124","url":null,"abstract":"<p><p>Prolonged exposure to high dosages of dexamethasone, which is a synthetic glucocorticoid and a well-known anti-inflammatory drug, may lead to an increase in reactive oxygen species production, contributing to muscle wasting. The prevention of muscle atrophy by ingestion of functional foods is an attractive issue. In the last decade, natural antioxidant compounds have been increasingly investigated as promising molecules able to counteract oxidative-stress-induced muscle atrophy. Recently, we have demonstrated the antioxidant properties of two main olive oil polyphenols also known for their anticancer and anti-inflammatory activities in different cell models. Here, the preventive effect of tyrosol on dexamethasone-induced muscle atrophy has been investigated by means of morpho-functional approaches in C2C12 myotubes. Dexamethasone-treated cells showed a reduced fiber size when compared to control ones. While long and confluent myotubes could be observed in control samples, those exposed to dexamethasone appeared as immature syncytia. Dysfunctional mitochondria and the accumulation of autophagic vacuoles contributed to myotube degeneration and death. Tyrosol administration before glucocorticoid treatment prevented muscle wasting and rescued mitochondrial and lysosomal functionality. These findings demonstrate that tyrosol attenuates dexamethasone-induced myotube damage, and encourage the use of this natural molecule in preclinical and clinical studies and in synergy with other functional foods or physical activity with the aim to prevent muscle atrophy.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141759180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Aringhieri, G. Astrea, Daniela Marfisi, S. C. Fanni, G. Marinella, R. Pasquariello, Giulia Ricci, Francesco Sansone, Martina Sperti, A. Tonacci, F. Torri, Sabrina Matà, G. Siciliano, E. Neri, F. Santorelli, Raffaele Conte
We aim to develop a deep learning-based algorithm for automated segmentation of thigh muscles and subcutaneous adipose tissue (SAT) from T1-weighted muscle MRIs from patients affected by muscular dystrophies (MDs). From March 2019 to February 2022, adult and pediatric patients affected by MDs were enrolled from Azienda Ospedaliera Universitaria Pisana, Pisa, Italy (Institution 1) and the IRCCS Stella Maris Foundation, Calambrone-Pisa, Italy (Institution 2), respectively. All patients underwent a bilateral thighs MRI including an axial T1 weighted in- and out-of-phase (dual-echo). Both muscles and SAT were manually and separately segmented on out-of-phase image sets by a radiologist with 6 years of experience in musculoskeletal imaging. A U-Net1 and U-Net3 were built to automatically segment the SAT, all the thigh muscles together and the three muscular compartments separately. The dataset was randomly split into the on train, validation, and test set. The segmentation performance was assessed through the Dice similarity coefficient (DSC). The final cohort included 23 patients. The estimated DSC for U-Net1 was 96.8%, 95.3%, and 95.6% on train, validation, and test set, respectively, while the estimated accuracy for U-Net3 was 94.1%, 92.9%, and 93.9%. Both of the U-Nets achieved a median DSC of 0.95 for SAT segmentation. The U-Net1 and the U-Net3 achieved an optimal agreement with manual segmentation for the automatic segmentation. The so-developed neural networks have the potential to automatically segment thigh muscles and SAT in patients affected by MDs.
{"title":"Convolutional Neural Network-Based Automated Segmentation of Skeletal Muscle and Subcutaneous Adipose Tissue on Thigh MRI in Muscular Dystrophy Patients","authors":"G. Aringhieri, G. Astrea, Daniela Marfisi, S. C. Fanni, G. Marinella, R. Pasquariello, Giulia Ricci, Francesco Sansone, Martina Sperti, A. Tonacci, F. Torri, Sabrina Matà, G. Siciliano, E. Neri, F. Santorelli, Raffaele Conte","doi":"10.3390/jfmk9030123","DOIUrl":"https://doi.org/10.3390/jfmk9030123","url":null,"abstract":"We aim to develop a deep learning-based algorithm for automated segmentation of thigh muscles and subcutaneous adipose tissue (SAT) from T1-weighted muscle MRIs from patients affected by muscular dystrophies (MDs). From March 2019 to February 2022, adult and pediatric patients affected by MDs were enrolled from Azienda Ospedaliera Universitaria Pisana, Pisa, Italy (Institution 1) and the IRCCS Stella Maris Foundation, Calambrone-Pisa, Italy (Institution 2), respectively. All patients underwent a bilateral thighs MRI including an axial T1 weighted in- and out-of-phase (dual-echo). Both muscles and SAT were manually and separately segmented on out-of-phase image sets by a radiologist with 6 years of experience in musculoskeletal imaging. A U-Net1 and U-Net3 were built to automatically segment the SAT, all the thigh muscles together and the three muscular compartments separately. The dataset was randomly split into the on train, validation, and test set. The segmentation performance was assessed through the Dice similarity coefficient (DSC). The final cohort included 23 patients. The estimated DSC for U-Net1 was 96.8%, 95.3%, and 95.6% on train, validation, and test set, respectively, while the estimated accuracy for U-Net3 was 94.1%, 92.9%, and 93.9%. Both of the U-Nets achieved a median DSC of 0.95 for SAT segmentation. The U-Net1 and the U-Net3 achieved an optimal agreement with manual segmentation for the automatic segmentation. The so-developed neural networks have the potential to automatically segment thigh muscles and SAT in patients affected by MDs.","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141654982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Barría, María Gaitán-Padilla, Daniel Gomez-Vargas, Gonzalo Cardenas Ampuero, Kay Gitterman, Bessie Cordova, Camilo Diaz, Flavio Roberti
Understanding the differences in ventilatory responses during exercise between patients with fibromyalgia and those with other chronic pain disorders is crucial for developing effective therapeutic interventions, especially in exercise to identify the better physical therapy prescription. Both populations face unique challenges that impact their ability to engage in physical activity; yet, the underlying physiological responses can vary significantly. In this context, the methodology of this study entailed conducting a comparative analysis of the ventilatory response during exercise in patients with fibromyalgia and those with other chronic pain disorders. The experimental protocol included a total of 31 participants (n = 13 diagnosed with fibromyalgia and n = 18 diagnosed with other chronic pain conditions). All participants completed a stress test, where the ventilatory parameters were measured in three stages (i.e., resting, incremental exercise, and recovery). The results revealed significant differences (p<0.05) in ventilatory responses between both groups. Patients with fibromyalgia exhibited reduced time for the aerobic threshold and a higher respiratory frequency in the anaerobic threshold compared to those with other chronic pain disorders. Furthermore, fibromyalgia patients demonstrated higher values in the ventilatory coefficient during the test and in the recovery stage. In conclusion, these differences underscore the need for tailored exercise programs that specifically address the unique ventilatory challenges faced by fibromyalgia patients to improve their physical function and overall quality of life.
{"title":"Comparative Analysis of Ventilatory Responses during Stress Tests in Patients with Chronic Pain: Implications for Therapeutic Interventions","authors":"P. Barría, María Gaitán-Padilla, Daniel Gomez-Vargas, Gonzalo Cardenas Ampuero, Kay Gitterman, Bessie Cordova, Camilo Diaz, Flavio Roberti","doi":"10.3390/jfmk9030122","DOIUrl":"https://doi.org/10.3390/jfmk9030122","url":null,"abstract":"Understanding the differences in ventilatory responses during exercise between patients with fibromyalgia and those with other chronic pain disorders is crucial for developing effective therapeutic interventions, especially in exercise to identify the better physical therapy prescription. Both populations face unique challenges that impact their ability to engage in physical activity; yet, the underlying physiological responses can vary significantly. In this context, the methodology of this study entailed conducting a comparative analysis of the ventilatory response during exercise in patients with fibromyalgia and those with other chronic pain disorders. The experimental protocol included a total of 31 participants (n = 13 diagnosed with fibromyalgia and n = 18 diagnosed with other chronic pain conditions). All participants completed a stress test, where the ventilatory parameters were measured in three stages (i.e., resting, incremental exercise, and recovery). The results revealed significant differences (p<0.05) in ventilatory responses between both groups. Patients with fibromyalgia exhibited reduced time for the aerobic threshold and a higher respiratory frequency in the anaerobic threshold compared to those with other chronic pain disorders. Furthermore, fibromyalgia patients demonstrated higher values in the ventilatory coefficient during the test and in the recovery stage. In conclusion, these differences underscore the need for tailored exercise programs that specifically address the unique ventilatory challenges faced by fibromyalgia patients to improve their physical function and overall quality of life.","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141670655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Determining the reference base of anthropometric parameters on a sample of elite athletes is one of the foundations of further research and forming a clearer picture of each sport and sports discipline. In this study, the aim was to describe the anthropometric and somatotype profiles of elite Finn class sailors and to determine the differences in the measured parameters between sailors at different levels of general competitive success. The subject sample included 57 Finn class sailors who competed at the open Finn European Championship. A set of 25 anthropometric variables were applied. The sailors were divided into three groups according to their level of general competitive success using World Sailing Rankings. Finn sailors had higher average values in almost all morphological characteristics when compared to the sailors in other Olympic classes. Considering the average values of somatotype categories, we determined that Finn sailors fit the endomorphic mesomorph somatotype category (3.94 ± 1.19 − 5.50 ± 1.19 − 1.63 ± 0.74). Significant differences were observed between more-successful, medium, and less-successful sailors in the variables of age, body mass, muscle mass, arm muscle mass, and endomorphy rating. These results indicate the possibility of selection processes and/or adaptation to sailing occurring in the Finn class. The anthropometric characteristics of Finn sailors compared to sailors in Olympic classes further “support” the Finn class being called the “heavy dinghy” male class. This study on anthropometric parameters, determined via a sample of top Finn sailors, may be of great help to coaches and young sailors when deciding on the selection of an adult sailing class.
{"title":"Anthropometric and Somatotype Profile of Elite Finn Class Sailors","authors":"Luka Pezelj, Boris Milavić, Mirjana Milić","doi":"10.3390/jfmk9030121","DOIUrl":"https://doi.org/10.3390/jfmk9030121","url":null,"abstract":"Determining the reference base of anthropometric parameters on a sample of elite athletes is one of the foundations of further research and forming a clearer picture of each sport and sports discipline. In this study, the aim was to describe the anthropometric and somatotype profiles of elite Finn class sailors and to determine the differences in the measured parameters between sailors at different levels of general competitive success. The subject sample included 57 Finn class sailors who competed at the open Finn European Championship. A set of 25 anthropometric variables were applied. The sailors were divided into three groups according to their level of general competitive success using World Sailing Rankings. Finn sailors had higher average values in almost all morphological characteristics when compared to the sailors in other Olympic classes. Considering the average values of somatotype categories, we determined that Finn sailors fit the endomorphic mesomorph somatotype category (3.94 ± 1.19 − 5.50 ± 1.19 − 1.63 ± 0.74). Significant differences were observed between more-successful, medium, and less-successful sailors in the variables of age, body mass, muscle mass, arm muscle mass, and endomorphy rating. These results indicate the possibility of selection processes and/or adaptation to sailing occurring in the Finn class. The anthropometric characteristics of Finn sailors compared to sailors in Olympic classes further “support” the Finn class being called the “heavy dinghy” male class. This study on anthropometric parameters, determined via a sample of top Finn sailors, may be of great help to coaches and young sailors when deciding on the selection of an adult sailing class.","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141674632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jose Teixeira, Luís Branquinho, Miguel Leal, Ryland Morgans, Andrew Sortwell, T. M. Barbosa, A. Monteiro, Pedro Afonso, Guilherme Machado, Samuel Encarnação, Ricardo Ferraz, Pedro Forte
The aim of this study was to analyze the match-to-match variation in high-intensity demands from one Portuguese professional football team according to playing positions. Twenty-three male outfield professional football players were observed during eighteen matches of the Portuguese Second League. Time–motion data were collected using Global Positioning System (GPS) technology. Match running performance was analyzed based on the following three playing positions: defenders (DF), midfielders (MF), and forwards (FW). Repeated measures ANOVA was utilized to compare match running performance within each position role, and seasonal running variation. Practical differences were assessed using the smallest worthwhile change (SWC), coefficient of variation (CV), and twice the coefficient of variation (2CV). Significant differences were found among playing positions in total distance covered (F = 15.45, p < 0.001, η2 = 0.33), average speed (F = 12.79, p < 0.001, η2 = 0.29), high-speed running (F = 16.93, p < 0.001, η2 = 0.36), sprinting (F = 13.49, p < 0.001, η2 = 0.31), accelerations (F = 4.69, p = 0.001, η2 = 0.132), and decelerations (F = 12.21, p < 0.001, η2 = 0.284). The match-to-match running performance encompassed TD (6.59%), AvS (8.67%), HSRr (37.83%), SPR (34.82%), ACC (26.92%), and DEC (27.85%). CV values for total distance covered ranged from 4.87–6.82%, with forwards and midfielders exhibiting the greatest and smallest variation, respectively. Midfielders demonstrated the highest match-to-match variation for all other analyzed variables (8.12–69.17%). All playing positions showed significant variation in high-demanding variables (26.94–37.83%). This study presents the initial analysis of match-to-match variation in high-intensity demands within a Portuguese professional football team. Thus, the position’s specificity and context can provide a helpful strategy for evaluating match-to-match running performance, and for recommending individualized training exercises based on the peak and high-intensity demands for each player’s role within the game.
{"title":"Match-to-Match Variation on High-Intensity Demands in a Portuguese Professional Football Team","authors":"Jose Teixeira, Luís Branquinho, Miguel Leal, Ryland Morgans, Andrew Sortwell, T. M. Barbosa, A. Monteiro, Pedro Afonso, Guilherme Machado, Samuel Encarnação, Ricardo Ferraz, Pedro Forte","doi":"10.3390/jfmk9030120","DOIUrl":"https://doi.org/10.3390/jfmk9030120","url":null,"abstract":"The aim of this study was to analyze the match-to-match variation in high-intensity demands from one Portuguese professional football team according to playing positions. Twenty-three male outfield professional football players were observed during eighteen matches of the Portuguese Second League. Time–motion data were collected using Global Positioning System (GPS) technology. Match running performance was analyzed based on the following three playing positions: defenders (DF), midfielders (MF), and forwards (FW). Repeated measures ANOVA was utilized to compare match running performance within each position role, and seasonal running variation. Practical differences were assessed using the smallest worthwhile change (SWC), coefficient of variation (CV), and twice the coefficient of variation (2CV). Significant differences were found among playing positions in total distance covered (F = 15.45, p < 0.001, η2 = 0.33), average speed (F = 12.79, p < 0.001, η2 = 0.29), high-speed running (F = 16.93, p < 0.001, η2 = 0.36), sprinting (F = 13.49, p < 0.001, η2 = 0.31), accelerations (F = 4.69, p = 0.001, η2 = 0.132), and decelerations (F = 12.21, p < 0.001, η2 = 0.284). The match-to-match running performance encompassed TD (6.59%), AvS (8.67%), HSRr (37.83%), SPR (34.82%), ACC (26.92%), and DEC (27.85%). CV values for total distance covered ranged from 4.87–6.82%, with forwards and midfielders exhibiting the greatest and smallest variation, respectively. Midfielders demonstrated the highest match-to-match variation for all other analyzed variables (8.12–69.17%). All playing positions showed significant variation in high-demanding variables (26.94–37.83%). This study presents the initial analysis of match-to-match variation in high-intensity demands within a Portuguese professional football team. Thus, the position’s specificity and context can provide a helpful strategy for evaluating match-to-match running performance, and for recommending individualized training exercises based on the peak and high-intensity demands for each player’s role within the game.","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Centorbi, Giulia Di Martino, Carlo della Valle, E. Iuliano, Gloria Di Claudio, Amelia Mascioli, G. Calcagno, A. di Cagno, Andrea Buonsenso, G. Fiorilli
Three years after the SARS-CoV-19 pandemic, a chronic post-COVID syndrome “LONG COVID” persists, causing fatigue and shortness of breath, along with distress, anxiety, and depression. Aim: To assess the impact of physical activity on the management and rehabilitation of LONG COVID, as well as to investigate the persistence of LONG COVID symptomatology in individuals over 40 years, beyond the pandemic. Methods: A total of 1004 participants (aged 53.45 ± 11.35) were recruited through an online snowball sampling strategy to complete a web-based survey. The following questionnaires were administered: Physical Activity Scale for Elderly (PASE), Shortness of Breath Questionnaire (SOBQ), Patient Health Questionnaire-9 item (PHQ-9), Generalized Anxiety Disorder 7-item (GAD-7), and Fatigue Scale for Motor and Cognitive Functions (FSMC). Results: Significant gender differences were discovered, with women reporting higher symptoms than men (p < 0.001). Significant age differences were also found, with participants under 55 showing higher values than those over 55 (p < 0.001). No significant differences were found between aerobic and mixed physical activity (p > 0.05) while significant results emerged between physical activity groups and the no activity group (p < 0.001). The low-frequency group reported higher symptoms than the high-frequency group (all ps < 0.001). Conclusion: Regardless of the type of physical activity performed, our survey identified the frequency of training as a crucial factor to overcome LONG COVID symptoms; the challenge lies in overcoming the difficulties due to the persistent feelings of inefficiency and fatigue typical of those who have contracted the infection.
{"title":"Regular Physical Activity Can Counteract LONG COVID Symptoms in Adults over 40","authors":"M. Centorbi, Giulia Di Martino, Carlo della Valle, E. Iuliano, Gloria Di Claudio, Amelia Mascioli, G. Calcagno, A. di Cagno, Andrea Buonsenso, G. Fiorilli","doi":"10.3390/jfmk9030119","DOIUrl":"https://doi.org/10.3390/jfmk9030119","url":null,"abstract":"Three years after the SARS-CoV-19 pandemic, a chronic post-COVID syndrome “LONG COVID” persists, causing fatigue and shortness of breath, along with distress, anxiety, and depression. Aim: To assess the impact of physical activity on the management and rehabilitation of LONG COVID, as well as to investigate the persistence of LONG COVID symptomatology in individuals over 40 years, beyond the pandemic. Methods: A total of 1004 participants (aged 53.45 ± 11.35) were recruited through an online snowball sampling strategy to complete a web-based survey. The following questionnaires were administered: Physical Activity Scale for Elderly (PASE), Shortness of Breath Questionnaire (SOBQ), Patient Health Questionnaire-9 item (PHQ-9), Generalized Anxiety Disorder 7-item (GAD-7), and Fatigue Scale for Motor and Cognitive Functions (FSMC). Results: Significant gender differences were discovered, with women reporting higher symptoms than men (p < 0.001). Significant age differences were also found, with participants under 55 showing higher values than those over 55 (p < 0.001). No significant differences were found between aerobic and mixed physical activity (p > 0.05) while significant results emerged between physical activity groups and the no activity group (p < 0.001). The low-frequency group reported higher symptoms than the high-frequency group (all ps < 0.001). Conclusion: Regardless of the type of physical activity performed, our survey identified the frequency of training as a crucial factor to overcome LONG COVID symptoms; the challenge lies in overcoming the difficulties due to the persistent feelings of inefficiency and fatigue typical of those who have contracted the infection.","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Movement theory and the study of movement dysfunction mark a paradigm shift in the treatment of low back pain symptoms, the majority of which are mechanical in origin at the outset. Treating movement dysfunction centers around unified and consistent rehabilitation that defines proficient movement for the lumbopelvic spine. The purpose of this study is to document the improvement in pain and disability of 290 patients who underwent NeuroHAB Functional Movement Therapy to reverse their lumbopelvic movement dysfunction attributed to causing their back pain symptoms between 2019 and 2023. Oswestry Disability Index (ODI) scores were collected from each participant on three occasions: the first consultation, after a waiting period/pre-intervention, and after the eight-week intervention. A single-factor ANOVA of all three ODI data sets was conducted, along with supporting descriptive statistics. A post-hoc t-test pairwise comparison was conducted for accuracy. The average ODI 1 score (taken at the first consultation) was 15.26 ± 6.1% (CI: 14.3–16.2); ODI 2 (after a waiting period, before NeuroHAB) was 14.71 ± 6.0% (CI: 13.82–15.59); and ODI 3 (post-intervention) was 9.09 ± 8.6% (CI: 8.305–9.875). There was no significant change from ODI 1 to ODI 2 (between the consultation and waitlist control periods). However, a significant reduction between ODI 2 and ODI 3 was observed (pre- and post-intervention) (mean difference: 5.62, p ≤ 0.001), and a 40.41% reduction was observed between ODI 1 (the ODI score taken at the first consultation) and ODI 3 (the ODI score taken after NeuroHAB, post-intervention) (mean difference: 6.17, p ≤ 0.001). A 50% ODI reduction was reported in the “Crippled” category (mean difference 16.15, p ≤ 0.001). The inclusion of functional movement proficiency and stability in future guidelines is a necessary step towards meaningful improvement in epidemic levels of back pain-related clinical and economic morbidity.
运动理论和运动功能障碍研究标志着腰背痛症状治疗模式的转变，大多数腰背痛症状一开始都是机械性的。治疗运动功能障碍的核心是统一和持续的康复训练，以确定腰椎骨盆的熟练运动。本研究的目的是记录 290 名接受 NeuroHAB 功能性运动疗法的患者的疼痛和残疾改善情况，这些患者在 2019 年至 2023 年期间扭转了导致腰痛症状的腰椎运动功能障碍。在首次就诊、等待期/干预前和为期八周的干预结束后三次收集每位参与者的奥斯韦特里残疾指数（ODI）得分。对所有三个 ODI 数据集进行了单因素方差分析，并进行了辅助描述性统计。对准确性进行了事后 t 检验配对比较。ODI 1（首次就诊时）的平均得分为 15.26 ± 6.1% (CI：14.3-16.2)；ODI 2（等待期后，NeuroHAB 前）的平均得分为 14.71 ± 6.0% (CI：13.82-15.59)；ODI 3（干预后）的平均得分为 9.09 ± 8.6% (CI：8.305-9.875)。从 ODI 1 到 ODI 2（咨询期与候补对照期之间）没有明显变化。然而，ODI 2 和 ODI 3（干预前和干预后）之间出现了明显降低（平均差：5.62，p ≤ 0.001），ODI 1（首次就诊时的 ODI 分数）和 ODI 3（NeuroHAB 后的 ODI 分数，干预后）之间降低了 40.41%（平均差：6.17，p ≤ 0.001）。据报告，"残废 "类别的 ODI 降低了 50%（平均差异为 16.15，p ≤ 0.001）。将功能性运动熟练度和稳定性纳入未来的指南，是切实改善背痛相关临床和经济发病率流行水平的必要步骤。
{"title":"Effects of the NeuroHAB Program on Low Back Pain and Oswestry Disability Index Scores: A Retrospective Wait-List Control Study","authors":"B. Williams, David Johnson","doi":"10.3390/jfmk9030118","DOIUrl":"https://doi.org/10.3390/jfmk9030118","url":null,"abstract":"Movement theory and the study of movement dysfunction mark a paradigm shift in the treatment of low back pain symptoms, the majority of which are mechanical in origin at the outset. Treating movement dysfunction centers around unified and consistent rehabilitation that defines proficient movement for the lumbopelvic spine. The purpose of this study is to document the improvement in pain and disability of 290 patients who underwent NeuroHAB Functional Movement Therapy to reverse their lumbopelvic movement dysfunction attributed to causing their back pain symptoms between 2019 and 2023. Oswestry Disability Index (ODI) scores were collected from each participant on three occasions: the first consultation, after a waiting period/pre-intervention, and after the eight-week intervention. A single-factor ANOVA of all three ODI data sets was conducted, along with supporting descriptive statistics. A post-hoc t-test pairwise comparison was conducted for accuracy. The average ODI 1 score (taken at the first consultation) was 15.26 ± 6.1% (CI: 14.3–16.2); ODI 2 (after a waiting period, before NeuroHAB) was 14.71 ± 6.0% (CI: 13.82–15.59); and ODI 3 (post-intervention) was 9.09 ± 8.6% (CI: 8.305–9.875). There was no significant change from ODI 1 to ODI 2 (between the consultation and waitlist control periods). However, a significant reduction between ODI 2 and ODI 3 was observed (pre- and post-intervention) (mean difference: 5.62, p ≤ 0.001), and a 40.41% reduction was observed between ODI 1 (the ODI score taken at the first consultation) and ODI 3 (the ODI score taken after NeuroHAB, post-intervention) (mean difference: 6.17, p ≤ 0.001). A 50% ODI reduction was reported in the “Crippled” category (mean difference 16.15, p ≤ 0.001). The inclusion of functional movement proficiency and stability in future guidelines is a necessary step towards meaningful improvement in epidemic levels of back pain-related clinical and economic morbidity.","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141682349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blanca Román-Viñas, Fidanka Vasileva, R. Font-Lladó, S. Aznar-Laín, Fabio Jiménez-Zazo, Abel López-Bermejo, V. López-Ros, A. Prats-Puig
The objective was to evaluate changes in fitness after an integrated neuromuscular training (INT) intervention in primary school children and to evaluate how lifestyle behaviors and parental education modulate these changes. One hundred and seventy children (7.45 ± 0.34 years; 52% girls) were included. Cardiorespiratory fitness (half-mile run test), a 10 × 5 m shuttle run test, standing broad jump (SBJ), handgrip dynamometer, body mass index (BMI) and fat mass percentage (FM%) were assessed before and after the 3-month intervention (20 min of INT in the physical education class, twice per week). The Mediterranean diet (MD), sleep time and parental education level (PEL) were evaluated by questionnaires, and adherence to physical activity (PA) recommendations was measured with a triaxial accelerometer before the intervention. After the intervention, there were improvements in the 10 × 5 test and the SBJ. Only girls had improvements in the handgrip test, BMI SDS and FM%. After correcting for confounding variables, only BMI was significantly improved whereas strength improved in the participants non-compliant with the PA recommendations or pertaining to families of high PEL. The INT produced improvements in fitness in a brief period and in different subgroups of pupils (inactive and with diverse sociocultural environments).
{"title":"Lifestyle as a Modulator of the Effects on Fitness of an Integrated Neuromuscular Training in Primary Education","authors":"Blanca Román-Viñas, Fidanka Vasileva, R. Font-Lladó, S. Aznar-Laín, Fabio Jiménez-Zazo, Abel López-Bermejo, V. López-Ros, A. Prats-Puig","doi":"10.3390/jfmk9030117","DOIUrl":"https://doi.org/10.3390/jfmk9030117","url":null,"abstract":"The objective was to evaluate changes in fitness after an integrated neuromuscular training (INT) intervention in primary school children and to evaluate how lifestyle behaviors and parental education modulate these changes. One hundred and seventy children (7.45 ± 0.34 years; 52% girls) were included. Cardiorespiratory fitness (half-mile run test), a 10 × 5 m shuttle run test, standing broad jump (SBJ), handgrip dynamometer, body mass index (BMI) and fat mass percentage (FM%) were assessed before and after the 3-month intervention (20 min of INT in the physical education class, twice per week). The Mediterranean diet (MD), sleep time and parental education level (PEL) were evaluated by questionnaires, and adherence to physical activity (PA) recommendations was measured with a triaxial accelerometer before the intervention. After the intervention, there were improvements in the 10 × 5 test and the SBJ. Only girls had improvements in the handgrip test, BMI SDS and FM%. After correcting for confounding variables, only BMI was significantly improved whereas strength improved in the participants non-compliant with the PA recommendations or pertaining to families of high PEL. The INT produced improvements in fitness in a brief period and in different subgroups of pupils (inactive and with diverse sociocultural environments).","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study was based on the ultrasound evaluation of the patellar tendon dimensions in the anteroposterior and transversal approaches in sports practitioners (cyclists and volleyball players) and non-sports practitioners. Relationships between the patellar tendon length, width, and thickness with gender, age, height, the dominant limb, and level of physical activity were evaluated. The samples included cyclists, volleyball players, and non-sports practitioners between 15 and 25 years old. Individuals were positioned supine with 30 degrees of knee flexion for bilateral measurements. Sports practitioners presented with an increased patellar tendon length and thickness. There were significant differences bilaterally between sports and non-sports practitioners (p < 0.003). The three dimensions of the patellar tendon of both limbs presented correlations with the male gender (0.336 < r < 0.601), and values of moderate-to-strong intensity in the length of the patellar tendon was directly proportional to height (0.520 < r < 0.601). There was a significant difference between the patellar tendon width and age (p < 0.025). Regarding the level of physical activity, significant differences were found between low and high levels in the three dimensions bilaterally (p < 0.004). The study results indicate that gender, age, height, and level of physical activity impact patellar tendon dimensions. However, there are no associations with the dominant limb.
{"title":"Ultrasonographic Evaluation of the Patellar Tendon in Cyclists, Volleyball Players, and Non-Practitioners of Sports—The Influence of Gender, Age, Height, Dominant Limb, and Level of Physical Activity","authors":"Ângela Pissarra, Luis P Ribeiro, Sónia Rodrigues","doi":"10.3390/jfmk9030116","DOIUrl":"https://doi.org/10.3390/jfmk9030116","url":null,"abstract":"This study was based on the ultrasound evaluation of the patellar tendon dimensions in the anteroposterior and transversal approaches in sports practitioners (cyclists and volleyball players) and non-sports practitioners. Relationships between the patellar tendon length, width, and thickness with gender, age, height, the dominant limb, and level of physical activity were evaluated. The samples included cyclists, volleyball players, and non-sports practitioners between 15 and 25 years old. Individuals were positioned supine with 30 degrees of knee flexion for bilateral measurements. Sports practitioners presented with an increased patellar tendon length and thickness. There were significant differences bilaterally between sports and non-sports practitioners (p < 0.003). The three dimensions of the patellar tendon of both limbs presented correlations with the male gender (0.336 < r < 0.601), and values of moderate-to-strong intensity in the length of the patellar tendon was directly proportional to height (0.520 < r < 0.601). There was a significant difference between the patellar tendon width and age (p < 0.025). Regarding the level of physical activity, significant differences were found between low and high levels in the three dimensions bilaterally (p < 0.004). The study results indicate that gender, age, height, and level of physical activity impact patellar tendon dimensions. However, there are no associations with the dominant limb.","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141714569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elmina-Eleftheria Roditi, Themistoklis Tsatalas, Giorgos K Sakkas, Yiannis Koutedakis, Giannis Giakas, Christina Karatzaferi
It is generally accepted that local muscular fatigue can negatively affect position sense. Interestingly, it has been proposed that in women, position sense and neuromuscular coordination may be affected by fluctuations of estrogen and progesterone levels. The aim of this study was to examine the possible effect of localized muscle fatigue on knee joint position sense at two phases of the menses: follicular and luteal. Twenty physically active females aged 19-30 years, with normal menses, volunteered for this study. An isokinetic dynamometer was used to evaluate proprioception and perform the fatigue protocol of the knee extensors and flexors. Knee proprioception at rest and after fatigue at three knee target angles (30°, 45°, 60°) was measured. A three-way ANOVA analysis with repeated measures was performed. The results showed that the main effect of fatigue was significant, but no main effect of the menstrual cycle phase was found. Additionally, a main effect was found for the target angle (more flexed target knee joint angles were associated with larger angular error deviations). In conclusion, localized muscle fatigue can significantly reduce the accuracy of active knee joint repositioning in both the luteal and the follicular menstrual phases in young, physically active healthy women.
{"title":"Effects of Muscular Fatigue on Position Sense in Two Phases of the Menstrual Cycle.","authors":"Elmina-Eleftheria Roditi, Themistoklis Tsatalas, Giorgos K Sakkas, Yiannis Koutedakis, Giannis Giakas, Christina Karatzaferi","doi":"10.3390/jfmk9030115","DOIUrl":"10.3390/jfmk9030115","url":null,"abstract":"<p><p>It is generally accepted that local muscular fatigue can negatively affect position sense. Interestingly, it has been proposed that in women, position sense and neuromuscular coordination may be affected by fluctuations of estrogen and progesterone levels. The aim of this study was to examine the possible effect of localized muscle fatigue on knee joint position sense at two phases of the menses: follicular and luteal. Twenty physically active females aged 19-30 years, with normal menses, volunteered for this study. An isokinetic dynamometer was used to evaluate proprioception and perform the fatigue protocol of the knee extensors and flexors. Knee proprioception at rest and after fatigue at three knee target angles (30°, 45°, 60°) was measured. A three-way ANOVA analysis with repeated measures was performed. The results showed that the main effect of fatigue was significant, but no main effect of the menstrual cycle phase was found. Additionally, a main effect was found for the target angle (more flexed target knee joint angles were associated with larger angular error deviations). In conclusion, localized muscle fatigue can significantly reduce the accuracy of active knee joint repositioning in both the luteal and the follicular menstrual phases in young, physically active healthy women.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141759178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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