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Dermatological Aspects of COVID-19 COVID-19的皮肤病学方面
Pub Date : 2020-06-21 DOI: 10.22502/JLMC.V8I1.379
Alina Sharma
On 31 December 2019, Wuhan, the capital city of Hubei Province in China reported World Health Organization(WHO) about cases of pneumonia which were caused by a severe acute respiratorysyndrome coronavirus 2 (SARS-CoV-2) currently designated coronavirus disease (COVID-19). The infection rapidly spread throughout the world escalating the situation and WHO eventually declared COVID-19 as a global pandemic on 11 March 2020. It has already affected almost all aspects of health and society globally. With the current pandemic, dermatologists should be aware of dermatological aspects of SARS-CoV-2, its skin manifestations and general skin care.
2019年12月31日,中国湖北省省会武汉向世界卫生组织(世界卫生组织)报告了由严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引起的肺炎病例,目前被指定为冠状病毒病(新冠肺炎)。感染在世界各地迅速蔓延,使局势升级,世界卫生组织最终于2020年3月11日宣布新冠肺炎为全球大流行。它已经影响到全球卫生和社会的几乎所有方面。在当前的疫情中,皮肤科医生应该了解严重急性呼吸系统综合征冠状病毒2型的皮肤学方面、其皮肤表现和一般皮肤护理。
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引用次数: 0
Morphometric Study of Lumbar Intervertebral Spaces (discs) by Using MRI. 腰椎间盘的MRI形态计量学研究。
Pub Date : 2020-06-17 DOI: 10.22502/JLMC.V8I1.320
D. Mansur, P. Shrestha, S. Maskey, K. Sharma, S. Karki, Trishna Kisiju
Introduction: The radiological space between two vertebrae is known as intervertebral space (height) which corresponds to the thickness of the intervertebral disc. Lumbar intervertebral disc is the most important structure which maintains the spinal function. An early diagnosis of pathological changes in disc has clinical significance. Hence the study aimed to determine normal height of the intervertebral disc space and effect of aging. Methods: It was a cross-sectional analytical study performed on 106 images of MRI scans of lumbar region. Dimensions of lumbar intervertebral spaces (discs) such as the anterior, middle, posterior intervertebral space height were measured in millimeter. Results: The mean anterior intervertebral space height was gradually increased from L1-L2 level (6.91 mm) to L5-S1 level (13.55 mm). The middle intervertebral space height increased from L1-L2 level (7.89 mm) to L4-L5 level (11.96 mm) whereas at L5-S1 level, there was a decrease (11.10 mm). Similarly, the posterior intervertebral space height showed an increment from L1-L2 level (5.52 mm) to L4-L5 level (8.09 mm) except at L5-S1 level, where it was decreased (6.94 mm). All mean values were found to be higher in males than in females except posterior intervertebral space height. The height of disc was increased up to third or fourth decade followed by a decrease. Conclusion: Knowing the normal lumbar intervertebral space height could be helpful for clinicians to diagnose and plan for proper treatment. It may also help to generate baseline data and to produce proper devices for Nepalese population.
两个椎体之间的放射间隙称为椎间隙(高度),它对应于椎间盘的厚度。腰椎间盘是维持脊柱功能最重要的结构。早期诊断椎间盘病变具有重要的临床意义。因此,本研究旨在确定椎间盘间隙的正常高度及其对衰老的影响。方法:对106张腰椎MRI扫描图像进行横断面分析研究。腰椎间隙(椎间盘)的尺寸如前、中、后间隙高度以毫米为单位测量。结果:前路椎间隙平均高度由L1-L2水平(6.91 mm)逐渐增加至L5-S1水平(13.55 mm)。中间椎间隙高度从L1-L2水平(7.89 mm)增加到L4-L5水平(11.96 mm),而L5-S1水平下降(11.10 mm)。同样,除了L5-S1水平下降(6.94 mm)外,后椎间隙高度从L1-L2水平(5.52 mm)增加到L4-L5水平(8.09 mm)。除后椎间隙高度外,所有平均值男性均高于女性。椎间盘高度在第三或第四个十年增加,然后下降。结论:了解正常的腰椎间隙高度有助于临床医生诊断和制定适当的治疗方案。它也可能有助于产生基线数据和为尼泊尔人民生产适当的设备。
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引用次数: 2
The Relationship of The Mandibular Canal to The Roots of Impacted Third Molars- The Root Factor: A Panoramic Radiographic Study. 下颌管与阻生第三磨牙牙根的关系——牙根因素:一项全景x线摄影研究。
Pub Date : 2020-06-15 DOI: 10.22502/JLMC.V8I1.322
Harleen Bali, D. Yadav, K. Adhikari, S. Mahanta, Rupam Tripathi, B. Sapkota
Introduction: Third molar extractions are one of the most common reasons of injury to mandibular nerve and postoperative complications. Pre-operative assessment of pending doom is a must. In order to study the relations between change in Inferior Alveolar Canal (IAC) and Type, Class, and Level of impaction with radiographic root change of impacted third mandibular molar, we designed a study to assess the relationship of the mandibular canal to the roots of impacted third molar in reference to changes in roots and factors affecting it. Methods: This was a retrospective cross-sectional study wherein the panoramic radiographic records of subjects with impacted third molar were assessed for change in root and its correlation with change in IAC, Type, Class and Level of impacted mandibular third molar. Results: Roots of impacted third molar when in contact with IAC presented most often in our study subjects with the Darkening of roots in both sides {right side (16.79%) and left side (11.29%)} and both genders {males (right-14.29%, left-8.75%) and females (right-19.39%, left-13.94%)}. They were statistically significantly associated with interruption of white line of IAC, vertically impacted third molars and Pell and Gregory Class II, Level A of impaction. Conclusion: There is a need to properly identify radiographic risk predictor signs to avoid any surprises at the time of extraction and post operation complications following it.
引言:第三磨牙拔除是下颌神经损伤和术后并发症最常见的原因之一。必须对即将到来的厄运进行术前评估。为了研究下颌下牙槽管(IAC)的变化与阻生第三磨牙影像学牙根变化的阻生类型、类别和程度之间的关系,我们设计了一项研究,根据牙根的变化及其影响因素来评估下颌管与阻生第一磨牙牙根的关系。方法:这是一项回顾性横断面研究,其中评估了受试者阻生第三磨牙牙根的变化及其与IAC、阻生下颌第三磨牙类型、类别和水平变化的相关性。结果:在我们的研究对象中,当与IAC接触时,阻生第三磨牙的牙根最常出现在两侧(右侧(16.79%)和左侧(11.29%))以及性别(男性(右侧-14.29%,左侧-8.75%)和女性(右侧-19.39%,左侧-13.94%))的牙根变暗,垂直阻生的第三磨牙和Pell and Gregory II级,阻生A级。结论:有必要正确识别放射学风险预测体征,以避免在提取时出现任何意外和术后并发症。
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引用次数: 0
Pregnancy Outcome Among Primigravidae Aged 35 Years and Above: A Comparative Study 35岁及以上原鸟妊娠结局的比较研究
Pub Date : 2020-06-15 DOI: 10.22502/JLMC.V8I1.331
Kriti Singh, P. Shrestha, Jeena Baaniya, P. Gurung
Introduction: Maternal age is an important determinant of pregnancy outcome. Women aged 35 years ormore at their first pregnancy are considered high risk as they are associated with increased adverse maternaland perinatal outcomes. Methods: A retrospective, comparative study was carried out over a period of two years in a tertiary center. Each elderly primigravida was matched with two primigravidwomen aged 20-34 years who delivered during the same period. Secondary data on obstetric outcomes (diabetes, oligohydramnios, polyhydramnios, hypothyroidism), postpartum complications (post-partum hemorrhage, postpartum eclampsia) and perinatal outcome (intra-uterine growth restriction, prematurity, congenital anomalies, and neonatal death)of 82 elderly primigravidae (study group) was compared to 164 younger primigravida (control group) delivered during the period of study. The Chi Square test and Fisher’s Exact test were used for statistical analysis and p value of <0.05 was taken as level of significance. Results: During the study period, there were 15,012 deliveries and 82 of these were elderly primigravidae giving an incidence of 0.55%. The mean age of the elderly primigravidae was 36.8±2.16 years. The study group had more antepartum complications with preterm labor, diabetes in pregnancy, hypertensive disorders in pregnancy, multiple pregnancy and polyhydramnios (p<0.05). Seventy-one elderly primigravidae were delivered by caesarean section, the commonest indication being maternal request. The study group had higher incidence of post-partum hemorrhage but no perinatal mortality of significant proportion. Conclusion: Maternal age at the first pregnancy influences pregnancy and neonatal outcomes. Hence, elderly primigravidae should be considered as high risk and followed up accordingly.
产妇年龄是决定妊娠结局的重要因素。35岁以上首次怀孕的妇女被认为是高风险的,因为她们与不良的孕产妇和围产期结局增加有关。方法:回顾性比较研究进行了为期两年的三级中心。每名老年初迁妇女与两名在同一时期分娩的20-34岁的初迁妇女配对。将82例老年初产妇(研究组)的产科结局(糖尿病、羊水过少、羊水过多、甲状腺功能减退)、产后并发症(产后出血、产后子痫)和围产期结局(子宫内生长受限、早产、先天性异常和新生儿死亡)的次要数据与研究期间分娩的164例年轻初产妇(对照组)进行比较。采用卡方检验和Fisher’s Exact检验进行统计学分析,以p <0.05为显著性水平。结果:研究期间共分娩15012例,其中82例为老年初迁族,发生率0.55%。老年初迁族平均年龄36.8±2.16岁。研究组早产、妊娠期糖尿病、妊娠期高血压疾病、多胎妊娠、羊水过多发生率高于对照组(p<0.05)。71只高龄初产妇经剖宫产分娩,最常见的指征是产妇的要求。研究组的产后出血发生率较高,但围产儿死亡率无显著性增高。结论:产妇初孕年龄影响妊娠和新生儿结局。因此,应将老年初迁鸟视为高危人群并进行随访。
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引用次数: 0
Threat of Dengue Outbreak in Nepal in Context of COVID-19 Pandemic 2019冠状病毒病大流行背景下尼泊尔登革热疫情的威胁
Pub Date : 2020-06-13 DOI: 10.22502/JLMC.V8I1.365
P. Koirala, D. Tamrakar
The world has been chained with Corona Virus Disease (COVID-19) pandemic today. It has affected more than 200 countries in just about a few months since December 2019. The virus has engulfed the world at a momentum never seen before. Considering the chances of disease being spread through asymptomatic transmission, social distancing has become a norm. This has brought a huge shift in how we live, work or interact with each other. It is feared that after the pandemic is over, the world would suffer a period of economic loss, as huge as the greatest depression of the 1930s or even more. With the world making medievalinventions and science doing wonders, we seem helpless to fight this pandemic. It has also drawn usto a realization that pandemic response cannot be extemporaneous.
今天,世界已被冠状病毒病(新冠肺炎)大流行所束缚。自2019年12月以来,在短短几个月内,它已经影响了200多个国家。这种病毒以前所未有的势头席卷了世界。考虑到疾病通过无症状传播的可能性,保持社交距离已成为常态。这给我们的生活、工作或互动方式带来了巨大的转变。人们担心,在疫情结束后,世界将遭受一段时间的经济损失,就像20世纪30年代甚至更长时间的大萧条一样巨大。随着世界在中世纪创造发明,科学在创造奇迹,我们似乎对抗击这场流行病束手无策。它也让我们意识到,疫情应对不能是即兴的。
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引用次数: 1
COVID-19 in the UK- Experience from The Frontline 新冠肺炎在英国-来自前线的经验
Pub Date : 2020-06-11 DOI: 10.22502/JLMC.V8I1.372
K. Aryal
Start of the pandemicAt the end of February, I was undertaking a mini fellowship on Trans-anal Total Meso-rectal Excision (TaTME) in Switzerland. The number of cases infected with corona virus disease (COVID-19) and deaths were rising exponentially in Italy. As the virus hit the UK, I was still able to complete ‘Non-Technical Skills for Surgeons (NOTSS) for trainees’ course at the deanery office at Fulbourn, Cambridge on the 13th of March 2020. Effect on personal life - self isolationI had operating list on the 17th of March where an 81-year-old male having laparoscopic right hemicolectomy for cancer was listed. This patient was readmitted a week after being discharged from the hospital with collapse and it had become apparent that he acquired COVID-19 in the surgical ward. Fortunately, he recovered from this and remains well till date. The same day, my son had fever with some cough. I needed to self- isolate according to UK government guideline for two weeks as there was no facility for testing whether my son had contracted coronavirus or not. There were a lot of problems in getting food from the supermarket on the way back home as the shelves were empty, online food order was impossible but somehow, we managed with ourfriends delivering food for us at our front door.
2月底,我在瑞士接受了一项关于经肛门直肠全系膜切除术(TaTME)的小型研究。意大利冠状病毒病(COVID-19)感染病例和死亡人数呈指数级增长。当病毒袭击英国时,我仍然能够于2020年3月13日在剑桥富尔本的院长办公室完成“外科医生非技术技能(NOTSS)培训生”课程。对个人生活的影响——自我隔离3月17日,我有一份手术名单,名单上是一位81岁的男性,因癌症进行腹腔镜右半结肠切除术。该患者因晕倒出院一周后再次入院,显然是在外科病房感染的。幸运的是,他康复了,直到现在还很健康。同一天,我儿子发烧并咳嗽。我需要根据英国政府的指导方针自我隔离两周,因为没有检测我儿子是否感染了冠状病毒的设施。在回家的路上从超市买食物遇到了很多问题,因为货架是空的,网上订购食物是不可能的,但不知何故,我们和朋友一起在家门口为我们送了食物。
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引用次数: 0
Self-rating on Self-directed Learning: A Cross- Sectional Survey on a Cohort of Medical Undergraduates from Nepal. 自主学习的自我评价:尼泊尔医科大学生的横断面调查。
Pub Date : 2020-06-11 DOI: 10.22502/JLMC.V8I1.319
A. Atreya, S. Nepal, J. Acharya
Introduction: As medicine is an ever-changing field, it necessitates medical students to develop independent  learning skills for continuous learning process. Self-directed learning (SDL) is a learning strategy where students take the initiative to learn on their own. It is basically an independent study where the students use available resources and learn independently of the subject. Methods: This self-administered questionnaire study assessed five domains of SDL consisting of 60 items. The responses were made on a five-point Likert scale: from 5 = always to 1 = never. The level of self-directed learning was categorized as high, moderate and low if the scoring range was between 221-300, 141-220 or 60-140 respectively. Any student scoring in the range between 221 and 300 was considered an effective self- directed learner. Results: The present study found three out of four the students (74.7%, n=56) were active self-directed learners. However, one out of four students were half-way in becoming self-directed learners. Conclusion: SDL skill is crucial not only for the students but also for the clinicians in a complex learning process for continuous advancement of knowledge in medical profession. The findings of the present study showed that majority of the students were effective self-directed learners. The effectiveness of SDL process can be accomplished if the students are encouraged and motivated during Problem Based Learning (PBL) sessions. Identifying the factors that spark interest amongst the students to learn on their own can be achieved by active feedback sessions.
导读:医学是一个瞬息万变的领域,医学生必须培养独立学习的能力,以适应不断的学习过程。自主学习(Self-directed learning, SDL)是指学生主动自主学习的一种学习策略。它基本上是一种独立的学习,学生利用可用的资源,独立学习。方法:采用自填问卷法对SDL的5个领域进行评估,共60项。受访者的回答采用李克特五分制:从5 =总是到1 =从不。在221 ~ 300分、141 ~ 220分和60 ~ 140分之间分别划分为高、中、低自主学习水平。任何得分在221到300之间的学生都被认为是有效的自主学习者。结果:本研究发现四分之三的学生(74.7%,n=56)是积极的自主学习者。然而,四分之一的学生在成为自主学习者方面只走了一半。结论:在一个复杂的学习过程中,SDL技能不仅对学生,而且对临床医生在医学专业知识的不断进步至关重要。本研究的结果表明,大多数学生是有效的自主学习者。如果学生在基于问题的学习(PBL)过程中受到鼓励和激励,SDL过程的有效性就可以实现。通过积极的反馈环节,可以确定激发学生自主学习兴趣的因素。
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引用次数: 3
Preparedness of Community Hospital Against COVID-19 社区医院应对新冠肺炎的准备工作
Pub Date : 2020-06-10 DOI: 10.22502/JLMC.V8I1.360
Ijendra Prajapati, G. Kayastha
Government of Nepal (GoN) imposed a nationwide lockdown on 24th March, 2020 with an effort to limit the spread of novel corona virus which is responsible for corona virus disease (COVID-19). COVID-19 Nepal: Preparedness and Response Plan (NPRP) was implicated on April 2020 which stated Sukraraj Infectious and Tropical Disease Hospital (STIDH) in the capital, Kathmandu has been designated by the GoN as the primary hospital along with Patan Hospital and the Armed Police Forces Hospital in the Kathmandu Valley. The Ministry of Health and Population (MoHP) had requested the 25 hub and satellite hospital networks across the country; designated for managing mass casualty events; to be ready with infection prevention and control measures, and critical care beds where available. Hospitals with less than 50 beds viz community-based municipality hospitals were left feeble against the surge of the pandemic. Waiting for the aid and support from government was the only option for some hospitals that lacked resources to combat this invisible culprit of global pandemic. However, Nepal Korea Friendship Municipality Hospital (NKFMH) located in Thimi, Bhaktapur determined itself to fight against this pandemic withlimited resources. This hospital not only serves the local community but also patients coming from all over Province 3 due to government insurance facilities provided by this hospital. With interaction and support from the Hospital Director, Mayor of the municipality, Korea International Cooperation Agency (KOICA), Bhaktapur Red Cross, Hospital board, Hospital Staffs, Medical Team, Adminstration, Interpid and locals in the community prompt preparedness action plan was formulated through various meeting at different levels and acted upon.
尼泊尔政府(GoN)于2020年3月24日在全国范围内实施封锁,以限制导致冠状病毒疾病(新冠肺炎)的新型冠状病毒的传播。新冠肺炎尼泊尔:准备和应对计划(NPRP)涉及2020年4月,该计划称,尼泊尔政府已将首都加德满都的Sukraraj传染病和热带病医院(STIDH)与帕坦医院和加德满都山谷的武装警察部队医院一起指定为主要医院。卫生和人口部要求在全国建立25个中心和卫星医院网络;指定管理大规模伤亡事件;准备好感染预防和控制措施,并在可用的情况下提供重症监护病床。床位不足50张的医院,即以社区为基础的市政医院,在疫情激增的情况下显得软弱无力。等待政府的援助和支持是一些医院的唯一选择,这些医院缺乏资源来对抗这一全球疫情的隐形罪魁祸首。然而,位于巴克塔布尔Thimi的尼泊尔-韩国友好市医院(NKFMH)决心用有限的资源抗击这一流行病。由于该医院提供的政府保险设施,该医院不仅为当地社区提供服务,还为来自全省各地的患者提供服务。在医院院长、市市长、韩国国际协力事业团(KOICA)、巴克塔普尔红十字会、医院董事会、医院工作人员、医疗团队、行政部门、Interpid和社区当地人的互动和支持下,通过不同级别的各种会议制定了快速准备行动计划,并采取了行动。
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引用次数: 0
Dermatoglyphic Patterns Among Undergraduate Students of a Medical College: A Descriptive Cross-sectional Study 某医学院校本科生皮肤纹型:描述性横断面研究
Pub Date : 2020-06-10 DOI: 10.22502/JLMC.V8I1.315
Chandan Sintakala, P. Manandhar, N. Pandey
Introduction: Dermatoglyphics is the science that deals with the study of dermal ridge patterns on the digits, palms and soles as a whole. The present study is based on fingerprints related with the dermatoglyphic patterns of digits of hands. Apart from individual identification in institutions, it is also useful in forensic investigations to identify the criminals or dead bodies in accidental cases. This study aimed to find out the fingerprint patterns in right and left hands of undergraduate medical students. Methods: The study was performed in 200 students (97 males and 103 females) from first and second years of MBBS and B.Sc. nursing streams. The fingerprints were collected individually by pressing each of the finger tips on the stamp pad and then pressing it on A4 sized plain paper until the best finger print was observed. Results: Out of 2000 fingerprints, 1218(60.9%) were loops, 581 (29.05%) were whorls, 134(6.7%) were arches, and 67(3.35%) were composites. In males, there were 620 loops, 226 whorls, 98 arches and 26 composites whereas 602 loops, 351 whorls, 36 arches and 41 composites were found in females. Conclusion:The loop patterns were more common than other fingerprint patterns. Comparatively arches and loops were more common in males and whorls and composites in female.
简介:皮纹学是一门研究手指、手掌和足底真皮嵴图案的科学。本研究基于与手的手指的皮纹图案相关的指纹。除了在机构中进行个人识别外,在法医调查中,识别意外案件中的罪犯或尸体也很有用。本研究旨在了解医科大学生左右手的指纹图谱。方法:对200名来自MBBS和理学学士护理专业一年级和二年级的学生(97名男性和103名女性)进行研究。通过将每个指尖按压在印台上,然后将其按压在A4大小的普通纸上,直到观察到最佳指纹,来单独收集指纹。结果:在2000个指纹中,1218个(60.9%)是环状,581个(29.05%)是螺纹,134个(6.7%)是弓形,67个(3.35%)是复合指纹。男性有620个环、226个轮匝、98个拱和26个复合物,而女性有602个环、351个轮匝,36个拱和41个复合物。结论:环状指纹图谱较其他指纹图谱更为常见。相比之下,弓形和环状在雄性中更常见,而轮匝和复合物在雌性中更常见。
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引用次数: 0
“Solidarity Trial”: A Feeling of Trust Towards COVID-19 Treatments “团结试验”:对COVID-19治疗的信任感
Pub Date : 2020-06-10 DOI: 10.22502/JLMC.V8I1.335
Naresh Karki
Corona Virus Disease (COVID-19) drugs are not being developed at the pace in which the disease is spreading throughout the world. WHO and its partners have announced the worldwide clinical trial on 18th March 2020, known as “Solidarity Trial” for greater co-ordination of developments of drugs. “Solidarity Trialis an international clinical trial to help find an effective treatment for COVID-19”. The trial is randomized, open-label and adaptive. This trial will analyze four treatment options against standard of care, after recruiting patients from various countries, and then will approach to their relative effectiveness against the disease. The aim of this trial is to rapidly explore if any of the administered drugs will slow progression of disease or improve survival. The rationale of conducting “Solidarity Trial” is to reduce time taken by the trials. Randomized clinical trials generally take years to conduct, while, “Solidarity Trial” will reduce the duration by 80%. By enrolling patients from around the world, this trial might be able to provide result more rapidly than multiple small trials. Moreover, those small multiple trials will not be able to gather solid evidence required to determine the relative effectiveness of given unproven drugs.
冠状病毒病(COVID-19)药物的开发速度赶不上该疾病在全球蔓延的速度。世卫组织及其合作伙伴于2020年3月18日宣布了一项名为“团结试验”的全球临床试验,以加强药物开发的协调。团结试验是一项国际临床试验,旨在帮助找到COVID-19的有效治疗方法。该试验是随机、开放标签和自适应的。在从不同国家招募患者后,该试验将根据标准护理分析四种治疗方案,然后将探讨其对该疾病的相对有效性。这项试验的目的是快速探索是否有任何给药会减缓疾病进展或提高生存率。进行“团结审判”的理由是缩短审判所需的时间。随机临床试验通常需要数年时间进行,而“团结试验”将缩短80%的持续时间。通过招募来自世界各地的患者,该试验可能比多个小型试验更快地提供结果。此外,这些小规模的多重试验将无法收集到确定给予未经证实的药物的相对有效性所需的确凿证据。
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引用次数: 3
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