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The The Impact of COVID-19 on Immunization Services COVID-19对免疫服务的影响
Pub Date : 2020-06-07 DOI: 10.22502/JLMC.V8I1.366
S. Mathema
There was a time when epidemics were of interest only to historians. In spite of the knowledge of the risks of emergent infectious diseases, Coronavirus disease of 2019 (COVID-19) managed to disrupt the entire world. This new virus has the capacity to evade, adapt, diversify and persist. Human factors such as global travel, human-animal contact, urban crowding and ecological changes have helped favor the rapid spread. Epidemics are known to eventually resolve, whether succumbing to societal action or having exhausted the supplyof susceptible victims. COVID-19 too will be contained but it will leave a trail of devastating health consequences for low- and middle-income countries (LMIC) including Nepal.When governments responded in the hopes of slowing the course of the pandemic and reducing the total mortality, stringent controls were implemented, including school closures, bans on public gatherings, and other forms of isolation or quarantine. In Nepal, a nationwide complete lockdown commenced on the 24th March, 2020. This brought about a drastic decrease in demand for hospital services, mainly due to inaccessibility orthe health care seekers’ apprehension of contracting the virus during a hospital visit. Elective surgeries and procedures were temporarily discontinued and preventive care such as antenatal and well-baby visits came to a complete halt in majority of the institutions nationwide. Although mortality rates for COVID-19 appeared to be low in children and in women in the reproductive age, these groups might be disproportionately affected by thedisruption of routine health services, particularly in LMICs.
曾经有一段时间,流行病只有历史学家才感兴趣。尽管知道突发传染病的风险,2019年的冠状病毒疾病(新冠肺炎)还是扰乱了整个世界。这种新病毒具有躲避、适应、多样化和持久性的能力。全球旅行、人与动物的接触、城市拥挤和生态变化等人为因素有助于这种快速传播。众所周知,流行病最终会解决,无论是屈服于社会行动还是耗尽了易感受害者的供应。新冠肺炎也将得到控制,但它将给包括尼泊尔在内的中低收入国家(LMIC)留下毁灭性的健康后果。当各国政府做出反应,希望减缓疫情进程并降低总死亡率时,实施了严格的控制措施,包括关闭学校、禁止公众集会以及其他形式的隔离或检疫。尼泊尔于2020年3月24日开始全国全面封锁。这导致对医院服务的需求急剧下降,主要是由于无法获得服务,或者寻求医疗保健的人担心在医院就诊时感染病毒。选择性手术和程序暂时停止,全国大多数机构的产前检查和婴儿健康检查等预防性护理也完全停止。尽管新冠肺炎儿童和育龄妇女的死亡率似乎较低,但这些群体可能会受到常规卫生服务中断的不成比例的影响,尤其是在LMIC。
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引用次数: 1
Principles, Utility and Limitations of Pulse Oximetry in Management of COVID-19 脉搏血氧计在新冠肺炎治疗中的原理、应用和局限性
Pub Date : 2020-06-06 DOI: 10.22502/JLMC.V8I1.356
Lok Raj Joshi
Pulse oximetry is an essential component of the standard care of COVID-19 patients. In the context of the spreading COVID-19 pandemic for which no targeted therapy or vaccines are yet available, early identification of the severe cases or cases with high risk of severe disease and appropriate supportive treatment are of paramount importance to save lives. Pulse oximetry is a cheap, fast, easy to use, noninvasive, painless and accurate tool that allows real-time monitoring of hypoxemia. As the primary target of the disease is the respiratory system pulse oximetry provides an unparalleled way to assess the severity of the disease, guide supportive therapies and monitor the clinical status and response to treatment with greater benefits in the low-resource settings. All settings from the quarantine facilities at the ground level to the ICUs in the highest level hospitals can utilize it to achieve their goals. To get the best of this tool, it needs to be used properly and the findings interpreted carefully. Role of basic understanding of the physiological principles and technology behind its use and awareness of its limitations cannot be overemphasized. The pulse oximetry readings are interpreted in the context of blood hemoglobin concentration, tissue perfusion, arterial blood carbon dioxide concentration and oxygen supplementation status.
脉搏血氧仪是COVID-19患者标准护理的重要组成部分。在COVID-19大流行不断蔓延、目前尚无靶向治疗方法或疫苗的背景下,及早发现重症病例或重症高危病例并进行适当的支持性治疗,对于挽救生命至关重要。脉搏血氧仪是一种廉价、快速、易于使用、无创、无痛和准确的工具,可以实时监测低氧血症。由于该疾病的主要目标是呼吸系统,脉搏血氧仪提供了一种无与伦比的方法来评估疾病的严重程度,指导支持性治疗,监测临床状态和对治疗的反应,在低资源环境中具有更大的益处。从底层的隔离设施到最高级医院的icu,所有设置都可以利用它来实现其目标。为了充分利用这一工具,需要正确使用它,并仔细解释研究结果。对其使用背后的生理原理和技术的基本理解以及对其局限性的认识的作用再怎么强调也不为过。脉搏血氧仪读数在血液血红蛋白浓度、组织灌注、动脉血二氧化碳浓度和氧气补充状态的背景下进行解释。
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引用次数: 2
A Comparative Study Between Pneumatic and Laser Lithotripsy for Proximal Ureteric Calculus 输尿管近端结石气动碎石与激光碎石的比较研究
Pub Date : 2020-06-06 DOI: 10.22502/JLMC.V8I1.303
R. Koju, H. Joshi, S. Shrestha, R. Karmacharya, Narendra Shalike
Introduction: There are various modalities of breaking urinary tract calculus. The aim of this study was to compare outcome between laser and pneumatic lithotripsy in patients with upper ureteric calculus in terms of stone free rate, proximal migration and complication. Methods: This was a prospective comparative study done in 210 patients with upper ureteric calculus. The patients were randomized into two groups (Laser Lithotripsy and Pneumatic Lithotripsy) from April 2018 to June 2019. The main objective of both the procedures was to break stone into particles less than 3 mm which was confirmed by X-ray KUB and ultrasonography of abdomen and pelvis after six weeks and to compare effectiveness in terms of immediate stone free rate, proximal migration, operative duration and post-operative complication. Results: There was no difference in age, gender and stone size in both groups. Immediate stone free rate was 99.05% in Laser Lithotripsy and 76.19% in Pneumatic Lithotripsy (p value<0.001). Proximal migration in Laser Lithotripsy was 0.95% and 23.81% in Pneumatic Lithotripsy (p<0.001). There was significantly prolonged operative duration in Pneumatic Lithotripsy (14.7±4.77 min vs 13.31±3.24 in Laser Lithotripsy, p=0.014). Complications were more in Pneumatic Lithotripsy group, which was statistically significant (p=0.017). Conclusion: Both pneumatic and laser lithotripsy are effective and safe modalities for treating upper ureteric calculus, however laser has less chances of proximal migration and higher immediate stone free rate with less complication
导读:泌尿道结石有多种治疗方法。本研究的目的是比较激光和气压碎石术治疗输尿管上段结石的效果,包括结石的游离率、近端移位和并发症。方法:对210例输尿管上段结石患者进行前瞻性比较研究。2018年4月至2019年6月,患者随机分为两组(激光碎石术和气动碎石术)。两种手术的主要目的是将结石粉碎成小于3毫米的颗粒,6周后通过x线KUB和腹部和骨盆超声检查证实,并比较即时结石清除率、近端迁移、手术时间和术后并发症的有效性。结果:两组患者年龄、性别、结石大小均无差异。激光碎石的即刻结石清除率为99.05%,气压碎石的即刻结石清除率为76.19% (p值<0.001)。激光碎石近端移位率为0.95%,气压碎石近端移位率为23.81% (p<0.001)。气动碎石术的手术时间明显延长(14.7±4.77 min),激光碎石术的手术时间为13.31±3.24 min, p=0.014。气压碎石组并发症较多,差异有统计学意义(p=0.017)。结论:气动碎石和激光碎石是治疗输尿管上段结石安全有效的方法,激光碎石近端移位几率小,结石即刻清除率高,并发症少
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引用次数: 1
Virtual Learning during COVID-19 Pandemic: Pros and Cons 新冠肺炎大流行期间的虚拟学习:赞成和反对
Pub Date : 2020-06-06 DOI: 10.22502/JLMC.V8I1.363
Bipana Surkhali, C. K. Garbuja
The current outbreak of corona virus disease (COVID-19), declared as public health emergency of national and international concern by World Health Organization (WHO), led to unprecedented public health responses in Nepal and many countries around the world including travel restriction, closure of educational institutions, curfews in some places and quarantines. This pandemic has affected lives of millions in different ways in different geographic locations worldwide. Beyond the immediate threat to health, unemployment, insecurity, etc., education is one of the sensitive areas which has been affected tremendously, students in Nepal not being an exception. The closure of all educational institutions effective from 18th March, 2020 followed by the nationwide lockdown from 24th March, 2020 till date enforced by Government of Nepal (GoN) as an effort to limit the spread of COVID-19 has shed a light on numerous issues affecting the access to education. As per the United NationsEducational, Scientific and Cultural Organization (UNESCO) report 2020, a total of 1,190,287,189learners are currently affected constituting 68% of the total enrolled learners worldwide because of temporary or indefinite country wide school closures implemented by the respective governments in an attempt to slow the spread of COVID-19. In Nepal alone 8,796,624 students have reportedly been affected.
目前爆发的冠状病毒病(新冠肺炎)被世界卫生组织(世界卫生组织)宣布为国家和国际关注的突发公共卫生事件,导致尼泊尔和世界许多国家采取了前所未有的公共卫生应对措施,包括旅行限制、关闭教育机构、一些地方宵禁和隔离。这场疫情以不同的方式影响了全球不同地理位置数百万人的生活。除了对健康、失业、不安全等的直接威胁外,教育也是受到严重影响的敏感领域之一,尼泊尔的学生也不例外。尼泊尔政府(GoN)为限制新冠肺炎的传播,自2020年3月18日起关闭了所有教育机构,随后自2020年4月24日起实施全国封锁,直到今天,这一举措揭示了影响受教育机会的许多问题。根据联合国教育、科学及文化组织(教科文组织)2020年报告,由于各国政府为减缓新冠肺炎的传播而在全国范围内暂时或无限期关闭学校,目前共有1190287189名学生受到影响,占全世界注册学生总数的68%。据报道,仅在尼泊尔就有8796624名学生受到影响。
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引用次数: 34
Limitations of COVID-19 Fever Clinic as the First Point of Contact: Are We Relying Too Much? An Experience from a Tertiary Center 新冠肺炎发热门诊作为第一接触点的局限性:我们是否过于依赖?高等教育中心的经验
Pub Date : 2020-06-06 DOI: 10.22502/JLMC.V8I1.352
D. Shrestha
In Nepal, after the first case was diagnosed with Corona Virus Disease -19 (COVID -19) in a 32-year-old returnee from Wuhan, China on 13 January 2020, it took more than four months to reach a figure of 500 infected cases. Seventy of them have already recovered and returned home. However, the curve has been taking a steeper slope after the first 50 cases were documented. With the first mortality from COVID-19 confirmed on 16thMay, 2020, the fact that this pandemic is tightening its grip in the country is more evident now. And witheach passing day, more cases are being diagnosed. In such a situation, strategies of screening the infected/suspects are of paramount importance and those already in place should be strengthened. On March 19, the Nepal Medical Council asked all hospitals, both private and public, with over 100 beds to operate a separate fever clinics and postpone elective surgeries to conserve resources for an outbreak. Such fever clinicsaim at separating and filtering out the suspected/ diagnosed COVID-19 patients. Arguably started firstin Kathmandu Medical College, fever clinics now have been established and run in almost every largehealth care centers. United Nations International Children’s Emergency Fund (UNICEF) has been pivotal in supporting some of these centers. Rising up to the task, Lumbini Medical College and Teaching Hospital started its fever clinic from 22 March 2020 in a separate makeshift place which later moved to a more organized structure. The fever clinic is set up in a separate area in order to keep off suspected patients from the main hospital.
在尼泊尔,自2020年1月13日从中国武汉返回的一名32岁的人被诊断出患有第一例冠状病毒病(COVID -19)后,四个多月后感染病例才达到500例。其中70人已经康复并返回家园。然而,在记录了前50例病例后,曲线呈现出更陡的斜率。随着2020年5月16日确诊的首例COVID-19死亡病例,这场大流行正在该国收紧控制的事实现在更加明显。每天都有更多的病例被诊断出来。在这种情况下,筛查感染者/嫌疑人的战略至关重要,现有战略应得到加强。3月19日,尼泊尔医学委员会要求所有拥有100多个床位的私立和公立医院开设单独的发烧诊所,并推迟选择性手术,以节省资源应对疫情。这种发热门诊的目的是分离和过滤疑似/确诊的新冠肺炎患者。可以说,发烧门诊首先始于加德满都医学院,现在几乎在所有大型医疗中心都建立和运营。联合国国际儿童紧急基金(儿童基金会)在支持其中一些中心方面发挥了关键作用。为了完成这项任务,蓝毗尼医学院和教学医院从2020年3月22日开始在一个单独的临时场所开设发烧诊所,后来转移到一个更有组织的结构中。发热门诊设在一个单独的区域,以防止疑似病人进入主医院。
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引用次数: 0
COVID-19 And Lockdown: Be Logical in Relaxing It COVID-19和封锁:放松它是合乎逻辑的
Pub Date : 2020-06-03 DOI: 10.22502/JLMC.V8I1.361
R. Piryani, S. Piryani, S. Piryani, Dhana Ratna Shakya, M. Huq
Cambridge Dictionary defines ‘lockdown’ as a situation in which people are not allowed to enter or leave a building or area freely because of an emergency. Merriam-Webster outlines three definitions of lockdown: a) the confinement of prisoners to their cell for all or most of the day as a temporary security measure, b) an emergency condition in which people are temporarily prevented from entering or leaving a restricted area during a threat of danger and c) a temporary condition imposed by governmental authorities as during theoutbreak of an epidemic disease in which people are required to stay at their homes and refrain from orlimit activities outside the home involving public contact. Our focus, here, is on lockdown strategy adopted to contain corona virus disease 2019 (COVID-19) pandemic.
《剑桥词典》对“封锁”的定义是,由于紧急情况,人们不允许自由进出建筑物或区域。韦氏词典概述了“封锁”的三种定义:A)作为一种临时安全措施,将囚犯全天或大部分时间限制在牢房内;b)在危险威胁期间暂时阻止人们进入或离开限制区域的紧急情况;c)政府当局规定的临时情况,如在流行病爆发期间,要求人们呆在家中,避免或限制与公众接触的家庭以外活动。我们在这里的重点是为遏制2019年冠状病毒病(COVID-19)大流行而采取的封锁战略。
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引用次数: 6
Pattern of Head Injuries in Western Hilly Region of Nepal: A Hospital-based Cross-sectional Study 尼泊尔西部丘陵地区头部损伤模式:一项基于医院的横断面研究
Pub Date : 2020-06-02 DOI: 10.22502/JLMC.V8I1.297
S. Sah, B. Neupane, A. Atreya, Naresh Karki
Introduction: Subtle or gross structural changes of scalp, skull and its contents due to application of direct or indirect external force are known as head injuries. Head being the most vulnerable and prominent part of body, injuries to it cause major mortality and morbidity globally. This study focussed to find the pattern of traumatic head injuries in patients presented to Lumbini Medical College Teaching Hospital, Palpa, Nepal. Methods: The data was collected from 252 patients (164 males and 88 females) with head injuries attending Emergency or out-patient department of Neurosurgery of the institute. All patients with traumatic head injuries (scalp injury, skull fracture, intracranial haemorrhage and brain injury) were included in the study and brought dead patients and patients with non-traumatic brain lesions were excluded. Results: Among the various modes of head injuries, the most frequent was road traffic accidents accounting 125 (49.60%) cases and fall from height 108 (42.86%) cases was second to it followed by physical assault 12 (4.76%) and others 7(2.78%). Manner of injuries were unintentional in 238 (94.44%) of cases. Among males, intentional injuries were present in 5 (2.98%) cases and among females, 9 (10.72%) cases presented with intentional injuries. In 105 (41.67%) of the cases, head injuries were associated with injuries to the other body parts as well. Conclusion: The most common cause of head injury was found to be road traffic accident followed by fall from height. Intentional injuries were more common in females when compared to males.
引言:由于直接或间接外力的作用,头皮、颅骨及其内含物发生细微或严重的结构变化,称为头部损伤。头部是身体最脆弱、最突出的部位,其损伤在全球范围内造成重大死亡和发病。这项研究的重点是在尼泊尔帕尔帕蓝比尼医学院教学医院就诊的患者中发现创伤性头部损伤的模式。方法:收集252例颅脑损伤患者(男164例,女88例)的临床资料。所有外伤性头部损伤(头皮损伤、颅骨骨折、颅内出血和脑损伤)患者均纳入研究,并将死亡患者和非外伤性脑损伤患者排除在外。结果:在各类颅脑损伤中,道路交通事故发生率最高,为125例(49.60%),高空坠落108例(42.86%),其次为人身伤害12例(4.76%),其他7例(2.78%),非故意伤害238例(94.44%)。男性中有5例(2.98%)存在故意伤害,女性中有9例(10.72%)存在故意损伤。在105例(41.67%)病例中,头部损伤也与其他身体部位的损伤有关。结论:颅脑损伤最常见的原因是道路交通事故,其次是高处坠落。与男性相比,故意伤害在女性中更为常见。
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引用次数: 1
Need for Prioritizing Health: An Old War-Cry Reiterated By COVID-19 优先考虑健康的必要性:新冠肺炎重现的古老战争
Pub Date : 2020-06-02 DOI: 10.22502/JLMC.V8I1.341
R. Shrestha, S. Nepal, A. Atreya
The poor state of health care in Nepal will be burdened further following the SARS-CoV-2 pandemic. The government failed in timely stockpiling of medical supplies and equipment, development of health infrastructure, including laboratories and quarantine centres, restriction and screening of international travel and information dissemination to the general public. While efforts have now been made to increase the capacity for diagnostic test for SARS-CoV-2, the government still needs to further increase the availability and accessibility throughout the country. This would be the first step in fighting the pandemic. However, it is also important to prepare for the worst case. Similarly, advocacy programs should be developed to inform the general public and alleviate their fears about the disease. These measures would not only help Nepal’s capability to respond to the COVID-19 outbreak but could lay the foundations to improve the health of the citizens in general, even after this epidemic is controlled and could go a long way in developing trust of the government in the populace.
在SARS-CoV-2大流行之后,尼泊尔糟糕的卫生保健状况将进一步加重。政府未能及时储存医疗用品和设备,未能发展卫生基础设施,包括实验室和检疫中心,未能限制和筛选国际旅行,未能向公众传播信息。虽然现在已经努力提高对SARS-CoV-2的诊断测试的能力,但政府仍需要进一步提高全国范围内的可用性和可及性。这将是抗击这一流行病的第一步。然而,为最坏的情况做准备也很重要。同样,应该制定宣传计划,告知公众并减轻他们对这种疾病的恐惧。这些措施不仅有助于尼泊尔应对COVID-19疫情的能力,而且可以为改善一般公民的健康奠定基础,即使在疫情得到控制之后,也可以在很大程度上建立政府对民众的信任。
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引用次数: 0
COVID-19: Emerging Challenges for Students in Medicine and Schools in the United States COVID-19:美国医学院和学校学生面临的新挑战
Pub Date : 2020-06-02 DOI: 10.22502/JLMC.V8I1.359
Shrinit Babel, Surbhi Jain, L. Conger
The coronavirus pandemic has changed the world everywhere, including the lives of high schoolers in America. The sudden sharp rise in coronavirus cases forced the closure of schools in Mid-March to curb the further spread of the virus. Several end-of-the-year celebrations, school activities, and examinations were canceled. At the same time, the cancellations gave a chance for the youth to adapt to uncertain situations and learn adifferent perspective of life. Living in Florida, a state that battles hurricanes for almost half a year, school closures have become the norm: it is not rare for students to be reminded to keep their textbooks and notes home for a week or two. Prepared from past closures due to hurricanes, the school district board already had a virtual school platform, and the principal instructed all students to shift to Zoom and alternative eLearning. However, when the coronavirus pandemic led to the indefinite closure of high schools across the country, thiswas something new, different, and unexpected that school communities had to face.
冠状病毒大流行改变了世界各地,包括美国高中生的生活。冠状病毒病例的突然急剧上升迫使学校在3月中旬关闭,以遏制病毒的进一步传播。一些年终庆祝活动、学校活动和考试都被取消了。与此同时,取消活动给了年轻人一个机会,让他们适应不确定的情况,学习不同的人生观。生活在佛罗里达州,这个与飓风搏斗了近半年的州,学校停课已经成为常态:提醒学生把课本和笔记放在家里一两周并不罕见。从过去因飓风而关闭的学校中,学区委员会已经有了一个虚拟学校平台,校长指示所有学生转向Zoom和替代电子学习。然而,当冠状病毒大流行导致全国各地的高中无限期关闭时,这是学校社区不得不面对的新的、不同的和意想不到的事情。
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引用次数: 0
Validation of a Preoperative Scoring System to Predict Difficult Laparoscopic Cholecystectomy: A Nepalese Perspective 从尼泊尔的角度验证术前评分系统预测腹腔镜胆囊切除术的难度
Pub Date : 2020-06-02 DOI: 10.22502/JLMC.V8I1.323
S. Baral, Neeraj Thapa, R. Chhetri
Introduction: Preoperative prediction of the factors leading to difficulty or conversion in cholecystectomy could help plan the surgical strategies and possible outcomes beforehand. The present study aimed to predict and analyze risk factors using a scoring system deemed responsible for surgical difficulties in patients undergoing cholecystectomy for symptomatic cholelithiasis. Methods: This hospital based prospective study was conducted at Department of Surgery, Lumbini Medical College and Teaching Hospital, Nepal. Various factors considered preoperatively were gender, age, previous history of hospitalization, impacted stone, obesity, gall bladder wall thickness, pericholecystic collection, previous abdominal scar and palpable gall bladder. Results: Among 177 cases operated, the mean age ±SD of the patients was 47.72±17.54 years. Conversion rate was 7.9 %. At preoperative score of 5; sensitivity, specificity, positive predictive value and negative predictive value were 89.40% (CI: 83.36%-93.82%), 69.23% (CI: 48.21 %-85.67%), 94.41%(CI: 90.44%-96.79%) and 52.94% (CI: 39.85%-65.64%) respectively{Area under curve– 0.74, p=0.0001, CI (0.637-0.846)}. Multivariate analysis showed abdominal scar {p=0.02, OR (CI): 5.2 (1.2-21.8)}, previous hospitalization {p=0.001, OR(CI): 6.8(2.2-20.8)} and thickened gall bladder wall {p= 0.03, OR(CI): 3.6(1.1-11.5)} to be statistically significant risk factors. Conclusion: With possible prediction beforehand, high risk group of patients can be identified and dealt accordingly to generate good surgical outcome avoiding complications.
引言:术前预测导致胆囊切除术困难或转化的因素有助于提前计划手术策略和可能的结果。本研究旨在使用评分系统预测和分析因症状性胆结石而接受胆囊切除术的患者的手术困难的风险因素。方法:这项基于医院的前瞻性研究在尼泊尔蓝毗尼医学院外科和教学医院进行。术前考虑的各种因素包括性别、年龄、既往住院史、结石嵌顿、肥胖、胆囊壁厚度、胆囊周围积液、既往腹部疤痕和可触及的胆囊。结果:177例手术患者的平均年龄±SD为47.72±17.54岁。转化率为7.9%。术前评分为5分;敏感性、特异性、阳性预测值和阴性预测值分别为89.40%(CI:83.36%-93.82%)、69.23%(CI:48.21%-85.67%)、94.41%(CI:90.44%-96.79%)和52.94%(CI:39.85%-65.64%),既往住院{p=0.001,OR(CI):6.8(2.2-20.8)}和胆囊壁增厚{p=0.03,OR(CI:3.6(1.1-11.5)}是具有统计学意义的危险因素。结论:通过预先可能的预测,可以识别和处理高危人群,从而产生良好的手术效果,避免并发症。
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引用次数: 3
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Journal of Lumbini Medical College
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