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The Influence of Sepsis on the Molecular Structure of Bones: A Fourier Transform Infrared Spectroscopy Study. 脓毒症对骨骼分子结构的影响:傅里叶变换红外光谱研究。
Q3 Dentistry Pub Date : 2022-01-01 DOI: 10.1615/JLongTermEffMedImplants.2022041977
Andreas F Mavrogenis, Efthymia Malesiou, Orestis Tanis, Evanthia Mitsiokapa, Aikaterini Tsatsaragkou, Jane Anastassopoulou, Theophile Theophanides, Dimitra Dimotikali, Maria Koui

Fourier transform infrared spectroscopy was used to evaluate the molecular structure of bone tissues of patients who underwent revision of total hip and shoulder arthroplasty. The intensity increase of the spectral bands in the region of 3000-2850 cm-1 provided information about the increase of the lipophilic environment, which supported the formation of aggregates and amyloid protein formation. The appearance and the intensity increase of the "marker band" at 1744 cm-1 suggested protein peroxidation and inflammation progression. The shift of the amide I and amide II absorption bands from 1650 cm-1 and 1550 cm-1, respectively, to lower frequencies was related to changes of collagen conformation structure from α-helix to β-sheet and random coil. The appearance and shifts of the new bands in the region 1200-900 cm-1 were related with the increasing of glycosylation upon inflammation. Important was also the disappearance of the hydroxyapatite vPO43- absorption bands at the spectral regions 1200-900 cm-1 and 550-650 cm-1 indicated the osteolysis development. Moreover, the formation of corrosive metallic implants confirmed the effect of oxidative stress on the development of periprosthetic joint infection.

采用傅里叶变换红外光谱法对全髋关节肩关节置换术翻修后患者骨组织的分子结构进行了评价。在3000 ~ 2850 cm-1范围内,谱带强度的增加提供了亲脂环境增加的信息,支持了聚集体的形成和淀粉样蛋白的形成。1744 cm-1“标记带”的出现和强度增加提示蛋白过氧化和炎症进展。酰胺I和酰胺II吸收谱带分别从1650 cm-1和1550 cm-1向低频移动,与胶原构象结构从α-螺旋向β-片状和随机卷曲的变化有关。1200 ~ 900 cm-1区域新条带的出现和移位与炎症后糖基化的增加有关。重要的是,在1200-900 cm-1和550-650 cm-1光谱区域羟基磷灰石vPO43-吸收带的消失表明骨溶解的发生。此外,腐蚀性金属植入物的形成证实了氧化应激对假体周围关节感染发展的影响。
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引用次数: 1
Can Partially Threaded Cannulated Screws Be Better Designed to Maximize Purchase in the Sacrum? 部分螺纹空心螺钉可以更好地设计以最大化骶骨的购买量吗?
Q3 Dentistry Pub Date : 2022-01-01 DOI: 10.1615/jlongtermeffmedimplants.2021039485
Shawn E. Boomsma, Ishaq Ibrahim, N. Suneja, A. V. von Keudell, M. Weaver
Sacroiliac screw fixation involves the use of cannulated, partially or fully threaded screws. Current partially threaded screws have standardized thread lengths involving a small portion of the screw regardless of its overall length. Forty uninjured computed tomography images were evaluated for distances from the lateral iliac cortex to the lateral sacral cortex at the first and second sacral segments. No difference in measurements were observed for gender, age, or body mass index. Using a smooth segment value of 32 mm, a significant increase in thread lengths is achievable allowing for a novel sacroiliac screw design to achieve greater purchase in the sacrum.
骶髂螺钉固定包括使用空心、部分或全螺纹螺钉。目前的部分螺纹螺钉具有标准化的螺纹长度,涉及螺钉的一小部分,而不考虑其整体长度。40张未损伤的计算机断层图像评估了从髂外侧皮质到骶外侧皮质在第一和第二骶节的距离。没有观察到性别、年龄或体重指数的测量差异。使用32毫米的平滑段值,可以实现螺纹长度的显著增加,从而允许新的骶髂螺钉设计,以实现更大的骶骨购买量。
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引用次数: 0
Retrospective Multivariate Clinical Analysis of 2707 Dental Implants with Hydrophilic and Hydrophobic Surfaces: Survival Rates after Up to 5 Years. 2707例亲水性和疏水性牙种植体的回顾性多因素临床分析:5年后的存活率。
Q3 Dentistry Pub Date : 2022-01-01 DOI: 10.1615/jlongtermeffmedimplants.2021039884
Vanessa Helena Jamcoski, C. A. Cartelli, S. Bernardes, L. Trojan, Marcos Boaventura de Moura, G. Thomé
The aim of this retrospective study was to evaluate the long-term predictability of treatment using implants with hydrophobic and hydrophilic surfaces, according to clinical parameters and survival rates. Records from all patients who received dental implants between January 2013 and December 2014 at ILAPEO College were fully evaluated by two graduate dentists. Records with incomplete or unclear data were excluded from the study. The variables evaluated were demographic data, design of implants and prosthetic components, type of loading, data related to the patients' general health, and survival of implants and prostheses. The final retrospective sample comprised 776 patients with 2707 implants, with up to 5 years of follow-up. Survival rates of implants and prostheses were 97.93% and 98.77%, respectively. Implants with hydrophobic (97.87%) and hydrophilic (98.34%) surfaces exhibited similar survival rates. Considering the different types of loading, there was no statistically significant difference between loading protocols regarding implant survival rates. Unsuitable healing capacity, uncooperative and not motivated patient, loss of prosthesis, and peri-implant bone loss were confirmed statistically to be factors that may contribute to implant loss, according to hazard ratio and odds ratio. The present study showed similar and high overall survival rates for implant with both types of surfaces, in the long term. The surface treatment, implant model and loading protocol had no significant influence on implant loss. Therefore, the evaluated implant systems were able to offer a high predictability for both hydrophobic and hydrophilic implants.
这项回顾性研究的目的是根据临床参数和存活率,评估使用疏水和亲水表面种植体治疗的长期可预测性。2013年1月至2014年12月期间在ILAPEO学院接受种植牙的所有患者的记录由两名毕业牙医进行全面评估。数据不完整或不明确的记录被排除在研究之外。评估的变量包括人口统计数据、植入物和假体部件的设计、载荷类型、与患者总体健康相关的数据以及植入物和假体的存活。最终的回顾性样本包括776名患者和2707个种植体,随访时间长达5年。种植体和假体的成活率分别为97.93%和98.77%。疏水种植体(97.87%)和亲水种植体(98.34%)的存活率相似。考虑到不同的加载类型,不同的加载方案在种植体存活率方面没有统计学上的显著差异。根据风险比和优势比,统计证实愈合能力不适宜、患者不配合、不积极、假体丢失、种植体周围骨丢失是可能导致种植体丢失的因素。目前的研究表明,从长期来看,两种表面种植体的总体存活率相似且较高。表面处理、种植体模型和加载方式对种植体损失无显著影响。因此,评估的种植体系统能够为疏水和亲水种植体提供高度的可预测性。
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引用次数: 1
CBCT Analysis of Prevalence of the Canalis Sinuosus on the Alveolar Ridge in the Site of Endosseous Implant Placement: A Retrospective Study. 牙槽嵴窦管在骨内种植体位置的CBCT分析:回顾性研究。
Q3 Dentistry Pub Date : 2022-01-01 DOI: 10.1615/jlongtermeffmedimplants.2022039656
Jonua Fernandes, Subhasree Rohinikumar, Thiyaneswar Nessapan, Dimple Rani, R. Abhinav, P. Gajendran
This study aimed to perform a cone-beam computed tomography (CBCT) analysis in the Chennai population to check for the prevalence of the canalis sinuosus and its terminal branches in the site of endosseous implant placement in the alveolar ridge of the anterior maxilla. A retrospective analysis was conducted in Saveetha Dental College, Chennai. One hundred (50 male and 50 female) CBCT images that included the maxilla of patients aged 18-65 years were selected at random from the archives of the Oral Implantology Department, which were taken in the period from December 1, 2019 to November 30, 2020. Two examiners assessed all the scans with special training to identify this structure. The CBCTs were examined carefully for the presence of accessory canals and the side of occurrence, gender, relation in proximity to the anterior teeth (central incisors to the first premolar). The diameter of the canal was also noted as either less than 1 mm or greater than 1 mm. Our study showed that accessory canals of the canalis sinuous were identified in a total of 18 patients (4 female, 14 male). This shows that in our study, the prevalence of this structure amongst male patients was 14% and for female patients, it was 4%. This study shows that although the accessory canals of the canalis sinuous in the site of endosseous implant placement are rare, it must not be taken lightly because its occurrence still poses a significant risk of iatrogenic nerve damage, especially during implant placement procedures. In some individuals, the terminal branches of this canal or its accessory canals can sometimes be present in the site of placement of endosseous implants placed in the anterior maxilla. Lack of knowledge and awareness of this structure and the fact that its occurrence is often overlooked due to its rare occurrence causes the potential for iatrogenic damage to the nerve resulting in complications.
本研究旨在对金奈人群进行锥束计算机断层扫描(CBCT)分析,以检查上颌前牙槽嵴内种植体放置部位的窦管及其末端分支的患病率。回顾性分析在金奈Saveetha牙科学院进行。随机选取口腔种植科档案中18-65岁患者上颌骨CBCT图像100张(男50张,女50张),拍摄时间为2019年12月1日至2020年11月30日。两名审查员评估了所有经过特殊训练的扫描结果,以确定该结构。仔细检查cbct是否存在副管,发生的侧面,性别,靠近前牙(中门牙到第一前磨牙)的关系。管的直径也被记录为小于或大于1mm。我们的研究表明,共18例患者(女性4例,男性14例)发现了肛管的副管。这表明,在我们的研究中,这种结构在男性患者中的患病率为14%,在女性患者中为4%。本研究表明,虽然在骨内种植体放置部位的副管弯曲很少见,但不能掉以轻心,因为它的发生仍然有很大的医源性神经损伤的风险,特别是在种植体放置过程中。在某些个体中,该根管的末端分支或其附属根管有时会出现在上颌前牙内种植体放置的位置。由于缺乏对这种结构的认识和认识,以及由于其罕见发生而经常被忽视,这可能会导致神经的医源性损伤,从而导致并发症。
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引用次数: 1
A Literature Review on Implant Abutment Types, Materials, and Fabrication Processes. 种植体基台类型、材料及制作工艺的文献综述。
Q3 Dentistry Pub Date : 2022-01-01 DOI: 10.1615/JLongTermEffMedImplants.2022042720
Khushali K Shah, Vinay Sivaswamy

Dental implantology has made great strides since Dr. Brånemark introduced it to the world of dentistry. In terms of materials and fabrication processes, a wide range of implants and their implant abutments are now widely available in the market. Such a wide range would undoubtedly put the clinician in a quandary when it comes to selecting an acceptable abutment, one that is scientifically based and also has a high clinical rate of success. As a result, this literature review is a straightforward attempt to shed light on the wide range of implant-abutment types, materials and fabrications that are now easily accessible on the market, as well as offer an overview of each specific type to avoid further dilemma for its clinical intent.

自从bramatnemark博士将牙种植引入牙科界以来,牙种植学已经取得了巨大的进步。在材料和制造工艺方面,现在市场上有各种各样的种植体及其种植基台。如此广泛的范围无疑会使临床医生在选择可接受的基台时陷入困境,这种基台既要有科学依据,又要有很高的临床成功率。因此,这篇文献综述是一个直截了当的尝试,阐明了目前在市场上很容易获得的种植基台类型、材料和制造的广泛范围,并提供了每种特定类型的概述,以避免其临床意图进一步陷入困境。
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引用次数: 2
Analgesics/Anti-Inflammatory Drugs Preferred Following Implant Placement: A Retrospective Study. 植入后首选镇痛/抗炎药物:一项回顾性研究。
Q3 Dentistry Pub Date : 2022-01-01 DOI: 10.1615/jlongtermeffmedimplants.2021037302
Karthikeyan Murthykumar, A. Rajasekar, G. Kaarthikeyan
BACKGROUND In dentistry, pain is a rather inevitable perception that often plagues both the care provider and receiver. Pain, which was described by Rene Descartes in the sixteenth century, has been defined as an unpleasant sensory and emotional experience associated with tissue damage or described in terms of such damage. Various dental procedures also provoke a perception of anxiety that culminates with pain and exaggerates the perception of pain. Hence, adequate pain control and assurance are of utmost importance during and following implant surgery. AIM The aim of the present study was to assess the analgesics and anti-inflammatory drugs preferred following implant placement and also to find an association between gender, age, and various analgesics/anti-inflammatories prescribed following implant surgery. MATERIALS AND METHODS Retrospective data collection was conducted from June 2019 to March 2020 among 200 patients who underwent implant surgery, based on records management system software to analyze the most commonly prescribed analgesics/anti-inflammatory drugs following implant surgery. RESULTS Among 200 patients the frequency distribution showed that 87% of the patients were prescribed with combination of Aceclofenac (100 mg), Paracetamol (325 mg), and Serratiopeptidase (15 mg), 10% of the patients were prescribed with Paracetamol (650 mg), whereas 3% of the patients were prescribed with Piroxicam (20 mg). CONCLUSION The present study showed that combination of Aceclofenac, Paracetamol, and Serratiopeptidase was the commonly prescribed analgesic/anti-inflammatory drug for postoperative pain management following implant placement. Also there was no significant association between gender vs. various analgesics/anti-inflammatory drugs prescribed following implant placement.
在牙科中,疼痛是一种不可避免的感觉,经常困扰着护理提供者和接受者。16世纪,勒内·笛卡尔描述了疼痛,将其定义为一种与组织损伤相关的不愉快的感觉和情感体验,或者用这种损伤来描述。各种牙科手术也会引起焦虑感,这种焦虑感以疼痛为高潮,并夸大疼痛感。因此,在植入手术期间和之后,适当的疼痛控制和保证是至关重要的。目的本研究的目的是评估种植体植入后首选的镇痛和抗炎药物,并发现性别、年龄和种植体手术后使用的各种镇痛/抗炎药物之间的关系。材料与方法回顾性收集2019年6月至2020年3月200例种植体手术患者的数据,基于记录管理系统软件,分析种植体手术后最常用的镇痛/抗炎药物。结果200例患者中,87%的患者联用乙酰氯芬酸(100 mg)、扑热息痛(325 mg)和塞拉肽酶(15 mg), 10%的患者联用扑热息痛(650 mg), 3%的患者联用吡罗西康(20 mg)。结论本研究显示,Aceclofenac、扑热息痛和Serratiopeptidase联合应用是种植体置入术后疼痛管理的常用镇痛/抗炎药物。此外,性别与植入后使用的各种镇痛/抗炎药物之间也没有显著的关联。
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引用次数: 0
Commonly Used Implant Dimensions in the Posterior Maxilla - A Retrospective Study. 后上颌骨常用种植体尺寸的回顾性研究。
Q3 Dentistry Pub Date : 2022-01-01 DOI: 10.1615/jlongtermeffmedimplants.2021038617
Reshma Thirunavakarasu, M. Arun, R. Abhinav, Balaji Ganesh
Implant therapy is a treatment option to ensure prosthesis survival rate and it is also done as a fixed dental prosthesis for replacing single and multiunit gaps. Posterior maxilla often has insufficient bone quality and quantity; for this reason it makes implant placement challenging in the site. Posterior edentulous maxilla presents special challenges to implant surgeons that are unique to this region compared to other regions of the maxilla. Thus, the aim of this study is to determine the common implant dimensions used in posterior maxilla. Completed case sheets were collected from a private dental hospital software system. Case sheets were taken from June 2019 to March 2020. Data was retrieved and evaluated by two reviewers. The parameters taken were patients, age groups, gender, teeth indicated for implants (maxillary premolars and molars), implant height, and implant width. Two-hundred fifty-four implants have been placed on the posterior maxilla of which 139 were premolars and 115 were molars. There was no statistical significance between the implants placed in both males and females (p value: 0.274). Between the age groups, the highest number of implants was seen in 41-60 years (n = 146) followed by 17-40 years (n = 78) and finally > 61 years (n = 30). The p value was 0.000, which was statistically significant. Various implant sizes for posterior maxilla have been introduced due to its challenging site. Thus in our study, we can see there is a difference in sizes for premolars and molars. Implant dimensions with increased height are used in the premolars compared to the molars. Implant dimensions with increased width are used in the molars compared to the premolars. In general, implant width and implant height can range from 3.6 to 4.5 mm and implant height ranging from 9.50 to 12.00 mm.
种植体治疗是保证义齿成活率的一种治疗选择,也可作为固定义齿替代单单元和多单元间隙。后上颌骨常骨质和骨量不足;由于这个原因,它使植入物的位置具有挑战性。与上颌骨的其他区域相比,后无牙颌对种植外科医生提出了特殊的挑战。因此,本研究的目的是确定用于后上颌骨的常见种植体尺寸。完整的病例表是从一家私立牙科医院的软件系统中收集的。病例表采集时间为2019年6月至2020年3月。数据由两名审稿人检索和评估。采集的参数包括患者、年龄、性别、种植牙(上颌前磨牙和磨牙)、种植体高度和种植体宽度。在后上颌放置了254颗种植体,其中139颗为前磨牙,115颗为臼齿。男性和女性植入物的差异无统计学意义(p值:0.274)。在不同年龄组中,种植体数量最多的是41-60岁(n = 146),其次是17-40岁(n = 78),最后是61岁(n = 30)。p值为0.000,差异有统计学意义。由于后上颌骨具有挑战性的位置,各种种植体尺寸已被引入。因此,在我们的研究中,我们可以看到前磨牙和磨牙的大小是不同的。与磨牙相比,种植体尺寸增加的高度用于前磨牙。与前磨牙相比,种植体尺寸增加了宽度,用于磨牙。一般来说,种植体的宽度和高度可在3.6至4.5毫米之间,种植体的高度可在9.50至12.00毫米之间。
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引用次数: 1
Comparison of Risk Factors and Postoperative Outcomes in Syndesmosis Injuries with Various Ankle Fracture Types. 不同类型踝关节骨折联合损伤的危险因素及术后预后比较。
Q3 Dentistry Pub Date : 2022-01-01 DOI: 10.1615/jlongtermeffmedimplants.2022039614
R. Kong, Nicoletta A. Kijak, Jason Lee, M. Chung, Suriya Baskar, Gregory S. Penny, N. Suneja, Jaime A. Uribe
There is a lack of understanding of risk factors and postoperative outcomes of syndesmotic injuries with singular versus multipart fractures. A retrospective analysis was done between 2008 and 2016, utilizing the American College of Surgeons National Surgical Improvement Program database. Patients with open reduction and internal fixation of isolated lateral malleolus fractures, bimalleolar fractures, or trimalleolar fractures were identified. A total of 2045 patients underwent syndesmotic fixation. Subjects with bimalleolar or trimalleolar fractures were more likely than those with unimalleolar fractures to be Caucasian (odds ratio [OR] = 1.5 and 1.9), female (OR = 1.8 and 2.9), aged > 65 years (OR = 1.6 and 1.9), or have American Society of Anesthesiologists (ASA) classification III (OR =1.5 and 1.4) (all, P ≤ 0.028). Patients with a unimalleolar fracture were more likely than those with a bimalleolar or trimalleolar fracture to be male (OR = 1.8 and 2.9), African American (OR = 1.5 and 1.8), aged < 30 years (OR = 1.4 and 1.8), or present with an ASA I classification (OR = 1.6 and 2.0) (all, P ≤ 0.004). Subjects with bimalleolar or trimalleolar fractures were more likely than those with unimalleolar fractures to have lengthier hospital stays (OR = 1.8 and 2.1), while patients with trimalleolar fractures were more likely than those with unimalleolar fractures to have hypoalbuminemia (OR = 2.3), develop a complication (OR = 2.2) or an open wound (OR = 1.9), or to be readmitted (OR = 2.2) (all, P ≤ 0.036). In this study, comorbidity rates and adverse postoperative outcomes significantly increased as the number-part fractures increased in syndesmotic fixation patients. Risk factors also varied across fracture severity.
目前对单部位骨折与多部位骨折联合损伤的危险因素和术后结果缺乏了解。2008年至2016年期间,利用美国外科医师学会国家外科改进计划数据库进行了回顾性分析。对孤立性外踝骨折、双踝骨折或三踝骨折患者进行切开复位内固定。共有2045例患者接受了韧带联合固定。与单踝骨折患者相比,双踝或三踝骨折患者多为白种人(比值比[or] =1.5和1.9)、女性(比值比= 1.8和2.9)、年龄在50至65岁之间(比值比= 1.6和1.9)、美国麻醉医师学会(ASA)三级分类(比值比=1.5和1.4)(均P≤0.028)。单踝骨折患者比双踝或三踝骨折患者多为男性(or = 1.8和2.9)、非裔美国人(or = 1.5和1.8)、年龄< 30岁(or = 1.4和1.8)或ASA I级(or = 1.6和2.0)(均P≤0.004)。双踝或三踝骨折患者比单踝骨折患者住院时间更长(or = 1.8和2.1),而三踝骨折患者比单踝骨折患者更容易发生低白蛋白血症(or = 2.3),发生并发症(or = 2.2)或开放性伤口(or = 1.9),或再次入院(or = 2.2)(均P≤0.036)。在本研究中,合并症发生率和术后不良结果随着胫联合固定患者数部骨折的增加而显著增加。危险因素也因骨折严重程度而异。
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引用次数: 0
Allograft Extensor Mechanism Reconstruction in Salvage Revision Knee Arthroplasty: Surgical Technique. 修复性膝关节置换术中异体移植物伸肌机制重建:外科技术。
Q3 Dentistry Pub Date : 2022-01-01 DOI: 10.1615/JLongTermEffMedImplants.2022041634
Hosam E Matar, Benjamin V Bloch, Peter J James

Although extensor mechanism failure remains a catastrophic complication of knee arthroplasty, there are a number of contemporary techniques with reasonable outcomes that restore function. Chronic failures require advanced reconstruction techniques. Similar complication rates have been reported for the use of autografts, allografts, or mesh reconstructions. Here, we describe our surgical technique in allograft extensor mechanism reconstruction for chronic failures in salvage revision knee arthroplasty using a complete extensor mechanism allograft with a modified proximal fixation and case demonstrations.

虽然伸肌机制失效仍然是膝关节置换术的灾难性并发症,但有许多现代技术可以恢复功能。慢性故障需要先进的重建技术。自体移植物、同种异体移植物或补片重建的并发症发生率相似。在这里,我们描述了采用改良近端固定的完整伸肌机制同种异体移植物重建挽救性翻修膝关节置换术慢性失败的手术技术和案例演示。
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引用次数: 1
An Analysis of Implant Prosthesis and Its Dynamic Occlusal Contacts. 种植体修复体及其动态咬合接触分析。
Q3 Dentistry Pub Date : 2022-01-01 DOI: 10.1615/JLongTermEffMedImplants.2022038732
Suresh Venugopalan, Subhasree R, Thiyaneswaran N, Subhabrata Maiti

The prosthetic replacement is achieved for the functional aspect of the stomatognathic system. Achieving prosthetic occlusion is challenging and has an occlusal concept of its own when the type of prosthesis varies. The implant occlusion differs for its load transfer concept and longevity. The study was employed to assess the dynamic occlusal contact in implant occlusion through digital means. The study was carried out on implant prosthesis and its dynamic parameters were evaluated using T-Scan Novus (BioResearch, Inc., Brown Deer, WI, USA) in a university hospital setting after collecting 35 patients. Mandibular arch prosthesis tends to swing from high intensity to low or no contacts frequently and when the percentage of implant crown contact at 10% is present there is more of implant protected occlusion achieved. Use of T-Scan Novus can reveal more occlusal details in functional form which can help in achieving new treatment goals.

假体置换是为了实现口颌系统的功能方面。当假体的类型不同时,实现假体的咬合是具有挑战性的,并且有其自身的咬合概念。种植体咬合的不同之处在于其负荷转移概念和使用寿命。本研究旨在通过数字手段评估种植体咬合的动态咬合接触。在收集了35名患者后,在大学医院使用T-Scan Novus (BioResearch, Inc., Brown Deer, WI, USA)对种植体假体进行了研究,并对其动态参数进行了评估。下颌弓假体往往从高强度到低接触或不接触频繁地摆动,当种植体冠接触的百分比为10%时,种植体保护的咬合效果更好。使用T-Scan Novus可以在功能形式中显示更多的咬合细节,有助于实现新的治疗目标。
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引用次数: 2
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Journal of long-term effects of medical implants
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