Pub Date : 2001-01-01DOI: 10.5650/oleoscience.1.247
S. Kuribayashi
Various kinds of oil which can keep our skin emollient are widely used in cosmetic formulations. It is technically important to make oil into a gelling state in order to improve stability of cosmetic products. Dimethylpolysiloxane has become popular recently, because it has unique properties, such as smooth and non-greasy touch and water repellency. However, oil gelling agents, particularly a gelling agent of dimethylpolysiloxane are less found in cosmetic ingredients. Thus, the cross-linked polysiloxane which can swell in dimethylpolysiloxane forming a soft gel has newly been developed. Then modifying the above cross-linked polysiloxane made it possible to make oil, such as paraffins, esters, glycerides into a stable gel, and W/O type gel emulsions can also be obtained. In this paper, the structure and characteristics of the cross-linked polysiloxane are introduced together with some examples of cosmetic applications.
{"title":"Development and Cosmetic Application of Cross-linked Polysiloxane","authors":"S. Kuribayashi","doi":"10.5650/oleoscience.1.247","DOIUrl":"https://doi.org/10.5650/oleoscience.1.247","url":null,"abstract":"Various kinds of oil which can keep our skin emollient are widely used in cosmetic formulations. It is technically important to make oil into a gelling state in order to improve stability of cosmetic products. Dimethylpolysiloxane has become popular recently, because it has unique properties, such as smooth and non-greasy touch and water repellency. However, oil gelling agents, particularly a gelling agent of dimethylpolysiloxane are less found in cosmetic ingredients. Thus, the cross-linked polysiloxane which can swell in dimethylpolysiloxane forming a soft gel has newly been developed. Then modifying the above cross-linked polysiloxane made it possible to make oil, such as paraffins, esters, glycerides into a stable gel, and W/O type gel emulsions can also be obtained. In this paper, the structure and characteristics of the cross-linked polysiloxane are introduced together with some examples of cosmetic applications.","PeriodicalId":16191,"journal":{"name":"Journal of Japan Oil Chemists Society","volume":"60 1","pages":"247-254"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85539690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-01-01DOI: 10.1021/cen-09426-meetings1
鷺坂 将伸
{"title":"222nd ACS National Meeting に参加して","authors":"鷺坂 将伸","doi":"10.1021/cen-09426-meetings1","DOIUrl":"https://doi.org/10.1021/cen-09426-meetings1","url":null,"abstract":"","PeriodicalId":16191,"journal":{"name":"Journal of Japan Oil Chemists Society","volume":"37 1","pages":"1163-1164"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84091504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-01-01DOI: 10.5650/OLEOSCIENCE.1.33
T. Sakai, H. Sakai, K. Kamogawa, M. Abe
{"title":"New Aspects of Surfactant-free emulsion","authors":"T. Sakai, H. Sakai, K. Kamogawa, M. Abe","doi":"10.5650/OLEOSCIENCE.1.33","DOIUrl":"https://doi.org/10.5650/OLEOSCIENCE.1.33","url":null,"abstract":"","PeriodicalId":16191,"journal":{"name":"Journal of Japan Oil Chemists Society","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83587055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kazuo Watanabe, T. Nakahara, T. Yokochi, Shizuo Mohara, K. Yazawa
A 13C-labeled docosahexaenoic acid (DHA) highly enriched with 13C atoms was prepared using the DHA-producing Thraustochytrid, Schizochytrium sp. strain N1-27. Following 115h-cultivation with sodium acetate-1, 2-13C2 as the sole labeled carbon source, 2.53g/L total lipids were obtained from the cells. The 13C-labeled DHA ethyl ester was prepared from total lipids and fractionated to almost 100% purity with 53% recovery on HPLC. The 13C atom ratio was estimated at more than 97% from GC-MS. The productivity of labeled DHA was 0.29g/L. Other 13C-labeled fatty acids such as docosapentaenoic acid (DPA), eicosapentaenoic acid, and palmitic acid, were obtained as by-products. The present Thraustochytrid is thus shown useful for producing labeled DHA and DPA.
{"title":"Production of 13C-Labeled Docosahexaenoic Acid by a Thraustochytrid","authors":"Kazuo Watanabe, T. Nakahara, T. Yokochi, Shizuo Mohara, K. Yazawa","doi":"10.5650/JOS1996.49.1437","DOIUrl":"https://doi.org/10.5650/JOS1996.49.1437","url":null,"abstract":"A 13C-labeled docosahexaenoic acid (DHA) highly enriched with 13C atoms was prepared using the DHA-producing Thraustochytrid, Schizochytrium sp. strain N1-27. Following 115h-cultivation with sodium acetate-1, 2-13C2 as the sole labeled carbon source, 2.53g/L total lipids were obtained from the cells. The 13C-labeled DHA ethyl ester was prepared from total lipids and fractionated to almost 100% purity with 53% recovery on HPLC. The 13C atom ratio was estimated at more than 97% from GC-MS. The productivity of labeled DHA was 0.29g/L. Other 13C-labeled fatty acids such as docosapentaenoic acid (DPA), eicosapentaenoic acid, and palmitic acid, were obtained as by-products. The present Thraustochytrid is thus shown useful for producing labeled DHA and DPA.","PeriodicalId":16191,"journal":{"name":"Journal of Japan Oil Chemists Society","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2000-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87051019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Molecular orbital study was conducted so as to clarify the reactivity of nucleophilic substitution between phenoxide anions of tocopherols (Vitamin E) and catechins and the three-membered oxirane ring (binding site to biomolecules) of some mutagens. All stationary points including transition state structures (TSs) were optimized with no geometrical constraint at the PM3 level and energies of all species including TSs were evaluated at the Becke3LYP/3-21G level based on PM3 geometry. The reactions of model compounds of three tocopherols (β-, γ-, and δ-tocopherol) and catechins with ethylene oxide were examined. The tocopherols and catechins were found to possess nucleophilic reactive sites to which electrophilic mutagens each having oxirane ring could bind.Activation energy (ΔE≠) for the rate-determining C-C bond forming step for electrophilic substitution of phenoxide anions of three tocopherol models with ethylene oxide was found to range in 43-53kJ/mol. Predicted reactivity followed the order βγ<δ-tocopherol. The most stable TS was that for the reaction of δ-tocopherol model and had the lowest ΔE≠ (+43.3kJ/mol), at which electrophilic reaction occurs at the C-7 position. In catechin models, TS whose O-5 phenoxide anion reacts with ethylene oxide at the C-8 position had the lowest ΔE≠ (+40.5kJ/mol). These considerably small ΔE≠ suggest tocopherols and catechins to be capable of directly capturing electrophilic mutagens having the reactive oxirane ring and eliminating their activities so as to bind to biomolecules.
{"title":"Molecular Orbital Study on Binding Ability of Tocopherols and Catechins to Three-membered Reactive Sites of Mutagens","authors":"Toshiya Okajima, T. Akiyama, S. Kawaguchi","doi":"10.5650/JOS1996.49.1423","DOIUrl":"https://doi.org/10.5650/JOS1996.49.1423","url":null,"abstract":"Molecular orbital study was conducted so as to clarify the reactivity of nucleophilic substitution between phenoxide anions of tocopherols (Vitamin E) and catechins and the three-membered oxirane ring (binding site to biomolecules) of some mutagens. All stationary points including transition state structures (TSs) were optimized with no geometrical constraint at the PM3 level and energies of all species including TSs were evaluated at the Becke3LYP/3-21G level based on PM3 geometry. The reactions of model compounds of three tocopherols (β-, γ-, and δ-tocopherol) and catechins with ethylene oxide were examined. The tocopherols and catechins were found to possess nucleophilic reactive sites to which electrophilic mutagens each having oxirane ring could bind.Activation energy (ΔE≠) for the rate-determining C-C bond forming step for electrophilic substitution of phenoxide anions of three tocopherol models with ethylene oxide was found to range in 43-53kJ/mol. Predicted reactivity followed the order βγ<δ-tocopherol. The most stable TS was that for the reaction of δ-tocopherol model and had the lowest ΔE≠ (+43.3kJ/mol), at which electrophilic reaction occurs at the C-7 position. In catechin models, TS whose O-5 phenoxide anion reacts with ethylene oxide at the C-8 position had the lowest ΔE≠ (+40.5kJ/mol). These considerably small ΔE≠ suggest tocopherols and catechins to be capable of directly capturing electrophilic mutagens having the reactive oxirane ring and eliminating their activities so as to bind to biomolecules.","PeriodicalId":16191,"journal":{"name":"Journal of Japan Oil Chemists Society","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2000-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90543053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The paper is primarily based on the article that qualified for the 2000 Japan Oil Chemists' Society Award. Novel synthetic routes of functional materials and intermediates involving reactions of epoxides were established. Reactions of epoxides with halogen compounds gave insertion products of epoxide into carbon-halogen bonds. Reactions of epoxides with carbonyl compounds gave 1, 3-dioxolane compounds. Special surfactants containing chemically cleavable surfactants, ƒ¿, ƒÖ-type surfactants and others were developed. The major chemically cleavable surfactants each possessed a 1, 3-dioxolane ring as connecting group of hydrophobic moiety with the hydrophilic moiety. Chemically cleavable surfactants were useful as ecofriendly surfactants owing to lose surface activity subsequent to acid, base or ozone addition after usage and the resulting oily residue could be recovered. The surfactants were useful for producing of high purity polymer by emulsion polymerization. Properties of surfactant mixed system were studied. Sodium dodecylsufate (SDS) alkyl glucoside (AG) and SDS alkyl ethoxylate (AE) mixed systems showed greater dissociation of sodium ions of SDS than SDS alone. The SDS AG mixed system showed no molecular interaction in mixed micelles, while the SDS AE mixed system did so. Percent leakage of a liposome probe was found strongly dependent on composition of mixed surfactants.
{"title":"Synthesis and Applications of Functional Materials Related to Oleochemistry","authors":"T. Takeda","doi":"10.5650/JOS1996.49.1369","DOIUrl":"https://doi.org/10.5650/JOS1996.49.1369","url":null,"abstract":"The paper is primarily based on the article that qualified for the 2000 Japan Oil Chemists' Society Award. Novel synthetic routes of functional materials and intermediates involving reactions of epoxides were established. Reactions of epoxides with halogen compounds gave insertion products of epoxide into carbon-halogen bonds. Reactions of epoxides with carbonyl compounds gave 1, 3-dioxolane compounds. Special surfactants containing chemically cleavable surfactants, ƒ¿, ƒÖ-type surfactants and others were developed. The major chemically cleavable surfactants each possessed a 1, 3-dioxolane ring as connecting group of hydrophobic moiety with the hydrophilic moiety. Chemically cleavable surfactants were useful as ecofriendly surfactants owing to lose surface activity subsequent to acid, base or ozone addition after usage and the resulting oily residue could be recovered. The surfactants were useful for producing of high purity polymer by emulsion polymerization. Properties of surfactant mixed system were studied. Sodium dodecylsufate (SDS) alkyl glucoside (AG) and SDS alkyl ethoxylate (AE) mixed systems showed greater dissociation of sodium ions of SDS than SDS alone. The SDS AG mixed system showed no molecular interaction in mixed micelles, while the SDS AE mixed system did so. Percent leakage of a liposome probe was found strongly dependent on composition of mixed surfactants.","PeriodicalId":16191,"journal":{"name":"Journal of Japan Oil Chemists Society","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2000-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87281971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The amounts and compositions of wax esters (WE) of salted roe and salted and dried roe ('Karasumi') of the mullet, Mugil cephalus, caught in Australia were examined. Both salted and salted and dried roes contained large amounts of lipids (TL : 30.631.6% of dry weight) comprised almost entirely of WE (82.884.3%) consisting mainly of C32 and C34 components (53.161.1%) Fatty alcohols originating from WE were essentially saturated (83.586.4%) with the predominant component of 16 : 0 alcohol (59.363.4%). Each of monoenoic fatty alcohols (11.915.0%) comprised their isomers and the most abundant component was 16 : 1n-7 alcohol (5.89.2%). Appreciable amounts of odd chain fatty alcohols with 15 : 0 alcohol (3.1-12.0%) were also present. Component fatty acids in WE were more monoenoic (56.160.6%) with 16 : 1n-7 acid (34.038.8%) and polyenoic (26.631.1%) with 20 : 5n-3, 22 : 5n-3 and 22 : 6n-3 acids. Among triacylglycerols, 16 : 0 (32.934.6%), 16 : 1n-7 (16.622.5%) and 18 : 1n-7 (7.88.7%) acids were characteristic. No oxidation of polyenoic fatty acids in different lipid classes of salted and dried roe of mullet could be detected.
{"title":"Amount and Composition of Wax Esters in Salted and Dried Roe from Mullet of Australia","authors":"Kenji Hayashi, H. Kishimura","doi":"10.5650/JOS1996.49.1401","DOIUrl":"https://doi.org/10.5650/JOS1996.49.1401","url":null,"abstract":"The amounts and compositions of wax esters (WE) of salted roe and salted and dried roe ('Karasumi') of the mullet, Mugil cephalus, caught in Australia were examined. Both salted and salted and dried roes contained large amounts of lipids (TL : 30.631.6% of dry weight) comprised almost entirely of WE (82.884.3%) consisting mainly of C32 and C34 components (53.161.1%) Fatty alcohols originating from WE were essentially saturated (83.586.4%) with the predominant component of 16 : 0 alcohol (59.363.4%). Each of monoenoic fatty alcohols (11.915.0%) comprised their isomers and the most abundant component was 16 : 1n-7 alcohol (5.89.2%). Appreciable amounts of odd chain fatty alcohols with 15 : 0 alcohol (3.1-12.0%) were also present. Component fatty acids in WE were more monoenoic (56.160.6%) with 16 : 1n-7 acid (34.038.8%) and polyenoic (26.631.1%) with 20 : 5n-3, 22 : 5n-3 and 22 : 6n-3 acids. Among triacylglycerols, 16 : 0 (32.934.6%), 16 : 1n-7 (16.622.5%) and 18 : 1n-7 (7.88.7%) acids were characteristic. No oxidation of polyenoic fatty acids in different lipid classes of salted and dried roe of mullet could be detected.","PeriodicalId":16191,"journal":{"name":"Journal of Japan Oil Chemists Society","volume":"38 6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2000-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78357301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), n-3 polyunsaturated fatty acid (n-3PUFA), have been shown to have beneficial effects on what? The beneficial effects of n-3PUFA, especially EPA on bone metabolism in vitro and in vivo were examined in this study.Osteoblasts are bone forming cells, that produce prostaglandin E2, an endogenous potent bone resorbing factor. To clarify the effects of EPA on bone metabolism, the effects of EPA on MC3T3-E1 cells, osteoblast-like cells were studied. The addition of MC3T3-E1 cells to EPA, but not DHA, caused increased calcium accumulation and Von-Kossa staining. In vivo experiments, the effect of EPA on strength of the femur in ovariectomized and low calcium/vitamin D3 fed rats were studied. EPA abolished the effects of ovariectomy with consequent recovery of the bone strength.Preliminary epidemiology studies indicate EPA ingestion possibly useful for preventing loss of bone weight and strength with aging. These findings and epidemiological studies, demonstrate EPA and marine oil to possibly have beneficial effects for preventing and improving age-related osteoporosis
{"title":"N-3 Polyunsaturated Fatty Acids and Bone Metabolism","authors":"H. Hibino, I. Morita","doi":"10.5650/JOS1996.49.1391","DOIUrl":"https://doi.org/10.5650/JOS1996.49.1391","url":null,"abstract":"Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), n-3 polyunsaturated fatty acid (n-3PUFA), have been shown to have beneficial effects on what? The beneficial effects of n-3PUFA, especially EPA on bone metabolism in vitro and in vivo were examined in this study.Osteoblasts are bone forming cells, that produce prostaglandin E2, an endogenous potent bone resorbing factor. To clarify the effects of EPA on bone metabolism, the effects of EPA on MC3T3-E1 cells, osteoblast-like cells were studied. The addition of MC3T3-E1 cells to EPA, but not DHA, caused increased calcium accumulation and Von-Kossa staining. In vivo experiments, the effect of EPA on strength of the femur in ovariectomized and low calcium/vitamin D3 fed rats were studied. EPA abolished the effects of ovariectomy with consequent recovery of the bone strength.Preliminary epidemiology studies indicate EPA ingestion possibly useful for preventing loss of bone weight and strength with aging. These findings and epidemiological studies, demonstrate EPA and marine oil to possibly have beneficial effects for preventing and improving age-related osteoporosis","PeriodicalId":16191,"journal":{"name":"Journal of Japan Oil Chemists Society","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2000-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82724831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Functional properties and applications of several biosurfactants such as bile acids (BA), lung surfactants (LS) and so on have been so far studied particularly in the boundary fields between colloids and surface chemistry and medical science. The main themes are as follows; (1) Studies on colloidal and surface properties of various bile salts.Changes of the shapes and structures of mixed micelles prepared by mixing a bile salt with various mole fractions in aqueous solutions of the nonionic surfactant with homogeneous ethylene oxide chain length (C10E8) were estimated for various mixed ratios of bile salts. These are itemized as follows;(a) CMCs, structures, aggregation numbers and hydrophobicities of micelles for single bile salt systems and for aqueous binary mixed systems between one of bile salts and C10E8.(b) Absorption of vitamine E (VE) solubilized in micellar solutions of various bile salts by a rat small intestine.(2) Studies on the functions and developements of LS. The mechanism of a synthetic lung surfactant including surfactant proteins named “TA” developed by Fujiwara et al., being more effective for respiratory distress syndrome (RDS), was evaluated by surface rheology as follows;(a) Surface rheological properties of proteolipids, surfactant protein (SP-B, SP-C, SP-BC) and their mixtures containing lecithin, palmitic acid (PA) and egg phosphatidyl glycerol (EggPG) and the efficiency as LS.(3) Studies on the fundamental properties of liposomes.(a) Evaluation of phase transition temperature (Tc) of lipid liposomes by using a tautomerism of α-benzoylacetoanilide (BAA) and effects of addition of cholesterol.(b) Influences of addition of ionic and nonionic surfactants on the membrane of lipid liposomes.(4) Solubilities of insoluble drugs into water.(a) Dissolution of calcium bilirubinate disk as a model of a gallstone by some solvents.(b) Dissolution of dicrofenac sodium by the complexes formed among hydrotropic substances in water.
{"title":"Properties of Some Biosurfactants and Their Applications","authors":"M. Ueno","doi":"10.5650/JOS1996.49.1343","DOIUrl":"https://doi.org/10.5650/JOS1996.49.1343","url":null,"abstract":"Functional properties and applications of several biosurfactants such as bile acids (BA), lung surfactants (LS) and so on have been so far studied particularly in the boundary fields between colloids and surface chemistry and medical science. The main themes are as follows; (1) Studies on colloidal and surface properties of various bile salts.Changes of the shapes and structures of mixed micelles prepared by mixing a bile salt with various mole fractions in aqueous solutions of the nonionic surfactant with homogeneous ethylene oxide chain length (C10E8) were estimated for various mixed ratios of bile salts. These are itemized as follows;(a) CMCs, structures, aggregation numbers and hydrophobicities of micelles for single bile salt systems and for aqueous binary mixed systems between one of bile salts and C10E8.(b) Absorption of vitamine E (VE) solubilized in micellar solutions of various bile salts by a rat small intestine.(2) Studies on the functions and developements of LS. The mechanism of a synthetic lung surfactant including surfactant proteins named “TA” developed by Fujiwara et al., being more effective for respiratory distress syndrome (RDS), was evaluated by surface rheology as follows;(a) Surface rheological properties of proteolipids, surfactant protein (SP-B, SP-C, SP-BC) and their mixtures containing lecithin, palmitic acid (PA) and egg phosphatidyl glycerol (EggPG) and the efficiency as LS.(3) Studies on the fundamental properties of liposomes.(a) Evaluation of phase transition temperature (Tc) of lipid liposomes by using a tautomerism of α-benzoylacetoanilide (BAA) and effects of addition of cholesterol.(b) Influences of addition of ionic and nonionic surfactants on the membrane of lipid liposomes.(4) Solubilities of insoluble drugs into water.(a) Dissolution of calcium bilirubinate disk as a model of a gallstone by some solvents.(b) Dissolution of dicrofenac sodium by the complexes formed among hydrotropic substances in water.","PeriodicalId":16191,"journal":{"name":"Journal of Japan Oil Chemists Society","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2000-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84616156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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