Pub Date : 2020-01-01DOI: 10.5352/JLS.2020.30.10.860
Dohyeon Kim, Dong-Hyun Kim, Hyun-Woo Park, Jin Kwon Kim, Sam-Woong Kim, T. W. Kim, Byeong-Jin Lee, Daniel Son, Il-Suk Kim
Larvae Do Hyeong Kim, Dong Hyun Kim, Hyun Woo Park, Jin Kwon Kim, Sam Woong Kim, Tae Wan Kim, Byeong Jin Lee, Daniel Son and Il-Suk Kim* Noryang Elementary School, 60, Jemendang-gil, Geumnam-myeon, Hadong-gun, Gyeongnam 52352, Korea Mookggye Elementary School Cheongam Branch Office, 716, Cheonghak-ro, Cheongam-myeon, Hadong-gun 52310, Korea 3 City & Farmer, 3937-17, Jirisan-daero, Sancheong-gun, Geyongnam 52259, Korea Gene Analysis Center, Gyeongnam National University of Science & Technology, Jinju 52725, Korea Department of Animal Resources Technology, Gyeongnam National University of Science and Technology, Gyeongnam, Jinju 52725, Korea
{"title":"Egg Quality Characteristics of Layer Chickens Reared with Tenebrio molitor Larvae","authors":"Dohyeon Kim, Dong-Hyun Kim, Hyun-Woo Park, Jin Kwon Kim, Sam-Woong Kim, T. W. Kim, Byeong-Jin Lee, Daniel Son, Il-Suk Kim","doi":"10.5352/JLS.2020.30.10.860","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.10.860","url":null,"abstract":"Larvae Do Hyeong Kim, Dong Hyun Kim, Hyun Woo Park, Jin Kwon Kim, Sam Woong Kim, Tae Wan Kim, Byeong Jin Lee, Daniel Son and Il-Suk Kim* Noryang Elementary School, 60, Jemendang-gil, Geumnam-myeon, Hadong-gun, Gyeongnam 52352, Korea Mookggye Elementary School Cheongam Branch Office, 716, Cheonghak-ro, Cheongam-myeon, Hadong-gun 52310, Korea 3 City & Farmer, 3937-17, Jirisan-daero, Sancheong-gun, Geyongnam 52259, Korea Gene Analysis Center, Gyeongnam National University of Science & Technology, Jinju 52725, Korea Department of Animal Resources Technology, Gyeongnam National University of Science and Technology, Gyeongnam, Jinju 52725, Korea","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"233 1","pages":"860-866"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73486383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5352/JLS.2020.30.1.40
S. Sin, Won Min Jeong, Y. Kil, Dong Yeol Lee, Sang Gon Kim, Young-Min Goo
This study investigated the anti-bacterial and anti-inflammatory activities of Artemisia iwayomogi Kitamura for medical and food additive applications. A 70% methanol extract of A. iwayomogi Kitam. was fractionated with a series of solvents in order of increasing polarity; these fractionated extracts showed high 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) scavenging activity in the ethyl acetate fractions and high 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity in both the ethyl acetate and chloroform fractions. Levels of total phenolics and flavonoids were highest in the ethyl acetate fraction extracts. Eight bacteria were then treated with the A. iwayomogi Kitam. extract fractions and most showed similar or lower levels of anti-bacterial activity when compared to the control group, except for Staphylococcus aureus. In addition, the anti-oxidant activities of the ethyl acetate fractions of the A. iwayomogi Kitam. extract were higher than those of the other fractions. To confirm the anti-inflammatory activity of the extract fractions, we applied them to RAW 264.7 cells using LPS, and the results indicate that an ethyl acetate fraction at 250 μg/ml concentration inhibits nitric oxide production. This study demonstrates that an ethyl acetate fraction of A. iwayomogi Kitam. extract inhibits bacterial and inflammatory activities and could be useful as a potential source of bioactive compounds.
{"title":"Anti-inflammatory and Anti-bacterial Activities of Artemisia iwayomogi Kitamura Extract Fractions","authors":"S. Sin, Won Min Jeong, Y. Kil, Dong Yeol Lee, Sang Gon Kim, Young-Min Goo","doi":"10.5352/JLS.2020.30.1.40","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.1.40","url":null,"abstract":"This study investigated the anti-bacterial and anti-inflammatory activities of Artemisia iwayomogi Kitamura for medical and food additive applications. A 70% methanol extract of A. iwayomogi Kitam. was fractionated with a series of solvents in order of increasing polarity; these fractionated extracts showed high 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) scavenging activity in the ethyl acetate fractions and high 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity in both the ethyl acetate and chloroform fractions. Levels of total phenolics and flavonoids were highest in the ethyl acetate fraction extracts. Eight bacteria were then treated with the A. iwayomogi Kitam. extract fractions and most showed similar or lower levels of anti-bacterial activity when compared to the control group, except for Staphylococcus aureus. In addition, the anti-oxidant activities of the ethyl acetate fractions of the A. iwayomogi Kitam. extract were higher than those of the other fractions. To confirm the anti-inflammatory activity of the extract fractions, we applied them to RAW 264.7 cells using LPS, and the results indicate that an ethyl acetate fraction at 250 μg/ml concentration inhibits nitric oxide production. This study demonstrates that an ethyl acetate fraction of A. iwayomogi Kitam. extract inhibits bacterial and inflammatory activities and could be useful as a potential source of bioactive compounds.","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"87 1","pages":"40-44"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74955610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5352/JLS.2020.30.9.783
Dan-Hee Yoo, Leeinchul
{"title":"Antioxidant effect and iNOS, COX-2 Expression Inhibition on RAW 264.7 Cell of Mangifera indica L. Leafs","authors":"Dan-Hee Yoo, Leeinchul","doi":"10.5352/JLS.2020.30.9.783","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.9.783","url":null,"abstract":"","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"23 1","pages":"783-790"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74599426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5352/JLS.2020.30.3.230
S. Shin, E. Chung
{"title":"Genetic Effects of Molecular Markers Related to Carcass Traits in Hanwoo Cattle","authors":"S. Shin, E. Chung","doi":"10.5352/JLS.2020.30.3.230","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.3.230","url":null,"abstract":"","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"68 1","pages":"230-238"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88085182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5352/JLS.2020.30.11.990
Jin-Young Lee, J. Dong, J. Kang
{"title":"Effect of Allium cepa (red) and Angelica gigas Nakai on Hair-growth Promotion in C57BL/6 Mice","authors":"Jin-Young Lee, J. Dong, J. Kang","doi":"10.5352/JLS.2020.30.11.990","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.11.990","url":null,"abstract":"","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"56 1","pages":"990-998"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85824674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5352/JLS.2020.30.11.965
Yu Jin Oh, Hae Jin Cho, Hyun Sim Woo, Jun-Gi Byeon, Yeong-Su Kim, D. Kim
{"title":"Physiological Activity of Methanol Extracts from Sambucus sieboldiana var. miquelii (Nakai) Hara","authors":"Yu Jin Oh, Hae Jin Cho, Hyun Sim Woo, Jun-Gi Byeon, Yeong-Su Kim, D. Kim","doi":"10.5352/JLS.2020.30.11.965","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.11.965","url":null,"abstract":"","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"24 1","pages":"965-972"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79053658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5352/JLS.2020.30.6.563
Taewoo Kang
{"title":"Recent Perspectives on Oncoplastic Breast Surgery in Korea","authors":"Taewoo Kang","doi":"10.5352/JLS.2020.30.6.563","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.6.563","url":null,"abstract":"","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"33 1","pages":"563-569"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77694052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5352/JLS.2020.30.11.999
M. Seo, Yong pyo Shin, H. Lee, Minhee Baek, Joon-Ha Lee, In-woo Kim, Jae‐Sam Hwang, Mi-Ae Kim
The suppression of neuroinflammatory responses in microglial cells, well known as the main immune cells in the central nervous system (CNS), are considered a key target for improving the progression of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. Teleogryllus emma is widely consumed around the world for its broad-spectrum therapeutic effect. In a previous work, we performed transcriptome analysis on T. emma in order to obtain the diversity and activity of its antimicrobial peptides (AMPs). AMPs are found in a variety of species, from microorganisms to mammals. They have received much attention as candidates oftherapeutic drugs for the treatment of inflammation-associated diseases. In this study, we investigated the anti-neuroinflammatory effect of Teleogryllusine (VKWKRLNNNKVLQKIYFVKI-NH2) derived from T. emma on lipopolysaccharide (LPS) induced BV-2 microglia cells. Teleogryllusine significantly inhibited nitric oxide (NO) production without cytotoxicity, and reducing pro-inflammatory enzymes expression such as inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). In addition, Telegryllusine also inhibited the expression of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) through down-regulation of the mitogen-activated protein kinases (MAPKs) and nuclear factor kappa B (NF-κB) signaling pathway. These results suggest that T. emma-derived Teleogryllusine could be a good source of functional substances that prevent neuroinflammation and neurodegenerative diseases.
{"title":"Anti-neuroinflammatory Effect of Teleogryllus emma Derived Teleogryllusine in LPS-stimulated BV-2 Microglia","authors":"M. Seo, Yong pyo Shin, H. Lee, Minhee Baek, Joon-Ha Lee, In-woo Kim, Jae‐Sam Hwang, Mi-Ae Kim","doi":"10.5352/JLS.2020.30.11.999","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.11.999","url":null,"abstract":"The suppression of neuroinflammatory responses in microglial cells, well known as the main immune cells in the central nervous system (CNS), are considered a key target for improving the progression of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. Teleogryllus emma is widely consumed around the world for its broad-spectrum therapeutic effect. In a previous work, we performed transcriptome analysis on T. emma in order to obtain the diversity and activity of its antimicrobial peptides (AMPs). AMPs are found in a variety of species, from microorganisms to mammals. They have received much attention as candidates oftherapeutic drugs for the treatment of inflammation-associated diseases. In this study, we investigated the anti-neuroinflammatory effect of Teleogryllusine (VKWKRLNNNKVLQKIYFVKI-NH2) derived from T. emma on lipopolysaccharide (LPS) induced BV-2 microglia cells. Teleogryllusine significantly inhibited nitric oxide (NO) production without cytotoxicity, and reducing pro-inflammatory enzymes expression such as inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). In addition, Telegryllusine also inhibited the expression of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) through down-regulation of the mitogen-activated protein kinases (MAPKs) and nuclear factor kappa B (NF-κB) signaling pathway. These results suggest that T. emma-derived Teleogryllusine could be a good source of functional substances that prevent neuroinflammation and neurodegenerative diseases.","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"11 1","pages":"999-1006"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79972495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5352/JLS.2020.30.5.452
Eunji Kim, Seung-Wha Jo, Eun-Jung Yim, Kum-Suk Kim, B. Choi, Nam-rye Lee, Do-Youn Jung
This study was conducted to investigate the total lignin content and anti-oxidant activity in extracts of defatted sesame seeds (DSS) fermented with 15 strains of Bacillus subtilis. The anti-oxidant activities of DSS were analyzed both before and after fermentation. The total lignan content of the DSS extracts fermented with BCH3678 (1,613.8 mg/l) and BCH3572 (1,599.5 mg/l) were relatively high compared to other strains. Anti-oxidant activity was determined according to phenolic compound and flavonoid content and DPPH radical scavenging rate; the highest total phenolic compound content was provided by the DSS with SRCM103716 at 2,803.3 mg GAE/g which returned total flavonoid content of 1,553.1 mg/g as strong correlation of its anti-oxidant activity. The DSS extract fermented by SRCM103716 at 37°C for 24 hr showed the highest DPPH scavenging rate at 66.5%. The fermented DSS extracts, regardless of strain, demonstrated higher anti-oxidative activity than the unfermented control, and these results suggest that such extracts could be useful as a potential source of bioactive compounds.
{"title":"An Evaluation of the Anti-oxidant Activity of Fermented Defatted Sesame Seeds","authors":"Eunji Kim, Seung-Wha Jo, Eun-Jung Yim, Kum-Suk Kim, B. Choi, Nam-rye Lee, Do-Youn Jung","doi":"10.5352/JLS.2020.30.5.452","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.5.452","url":null,"abstract":"This study was conducted to investigate the total lignin content and anti-oxidant activity in extracts of defatted sesame seeds (DSS) fermented with 15 strains of Bacillus subtilis. The anti-oxidant activities of DSS were analyzed both before and after fermentation. The total lignan content of the DSS extracts fermented with BCH3678 (1,613.8 mg/l) and BCH3572 (1,599.5 mg/l) were relatively high compared to other strains. Anti-oxidant activity was determined according to phenolic compound and flavonoid content and DPPH radical scavenging rate; the highest total phenolic compound content was provided by the DSS with SRCM103716 at 2,803.3 mg GAE/g which returned total flavonoid content of 1,553.1 mg/g as strong correlation of its anti-oxidant activity. The DSS extract fermented by SRCM103716 at 37°C for 24 hr showed the highest DPPH scavenging rate at 66.5%. The fermented DSS extracts, regardless of strain, demonstrated higher anti-oxidative activity than the unfermented control, and these results suggest that such extracts could be useful as a potential source of bioactive compounds.","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"1 1","pages":"452-459"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84841724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.5352/JLS.2020.30.9.826
H. Jang, J. Choi, Jongsoo Chang
{"title":"Physiological Roles of Phospholipase Cγ and Its Mutations in Human Disease","authors":"H. Jang, J. Choi, Jongsoo Chang","doi":"10.5352/JLS.2020.30.9.826","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.9.826","url":null,"abstract":"","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"5 1","pages":"826-833"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89113641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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