{"title":"Diagnostic accuracy of doppler ultrasound scan in identifying morbid adherence in patients with placenta previa.","authors":"","doi":"10.7176/jmpb/54-12","DOIUrl":"https://doi.org/10.7176/jmpb/54-12","url":null,"abstract":"","PeriodicalId":16339,"journal":{"name":"Journal of Medicine, Physiology and Biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76911996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background; Laparoscopic cholecystectomy is one of the commonly performed surgical procedure these days which is associated with significant reduction of morbidities and mortality. This study was conducted to ascertain port site infection after laparoscopic cholecystectomy without using gloves. Objective; To determine frequency of port site infection (PSI) in patients undergoing laparoscopic cholecystectomy when gallbladder is removed without using gloves. Material and Methods; A total of 254 patients undergoing laparoscpic cholecystectomy were enrolled in our study. The laparoscopic cholecystectomy was performed and after removal of gall bladder without endogloves the laparoscope was moved to the epigastric port, and a large-tooth grasping forceps were inserted through the umbilical port to grasp the gallbladder at the area of the cystic duct and were followed for wound infection. Results; Of these 254 study cases, 98 (36.6 %) were male patients while 156 (61.4 %) were female patients. Mean age of our study cases was 49.58 ± 6.32 years. Of these 254 study cases, 89 (35.0 %) belonged to rural areas and 165 (65.0 %) belonged to urban areas. Diabetes was present in 68 (26.8 %) of our study cases. Hypertension was present in 126 (49.6 %) of our study cases. Mean duration of surgery was 55.28 ± 15.23 minutes and 185 (72.8 %) had duration of procedure up to 1 hour. Mean hospital stay was 5.22 ± 2.18 days and 204 (80.3%) had hospital stay up to 6 days. Umblical port site infection (PSI) was noted in 20 (7.9%). Conclusion; High frequency of umblical port site infection was noted in our study among patients undergoing laparoscopic cholecystectomy without using gloves, so use of gloves is safe, cost effective and reduces related morbidities. Port site infection was significantly associated with increasing, gender, diabetes, residential status, prolonged duration of surgery and duration of hospitalization. Keywords; Umblical Port site infection, gloves, Laparoscopic cholecystectomy DOI : 10.7176/JMPB/54-13 Publication date : April 30 th 2019
{"title":"PROLONGED POST – OPERATIVE HOSPITALIZATION PREDICTS HIGH BURDEN OF UMBLICAL PORT SITE INFECTION IN LAPAROSCOPIC CHOLECYSTECTOMY.","authors":"Abdul Hadi, M. Aqeel, Muhammad Shahbaz","doi":"10.7176/jmpb/54-13","DOIUrl":"https://doi.org/10.7176/jmpb/54-13","url":null,"abstract":"Background; Laparoscopic cholecystectomy is one of the commonly performed surgical procedure these days which is associated with significant reduction of morbidities and mortality. This study was conducted to ascertain port site infection after laparoscopic cholecystectomy without using gloves. Objective; To determine frequency of port site infection (PSI) in patients undergoing laparoscopic cholecystectomy when gallbladder is removed without using gloves. Material and Methods; A total of 254 patients undergoing laparoscpic cholecystectomy were enrolled in our study. The laparoscopic cholecystectomy was performed and after removal of gall bladder without endogloves the laparoscope was moved to the epigastric port, and a large-tooth grasping forceps were inserted through the umbilical port to grasp the gallbladder at the area of the cystic duct and were followed for wound infection. Results; Of these 254 study cases, 98 (36.6 %) were male patients while 156 (61.4 %) were female patients. Mean age of our study cases was 49.58 ± 6.32 years. Of these 254 study cases, 89 (35.0 %) belonged to rural areas and 165 (65.0 %) belonged to urban areas. Diabetes was present in 68 (26.8 %) of our study cases. Hypertension was present in 126 (49.6 %) of our study cases. Mean duration of surgery was 55.28 ± 15.23 minutes and 185 (72.8 %) had duration of procedure up to 1 hour. Mean hospital stay was 5.22 ± 2.18 days and 204 (80.3%) had hospital stay up to 6 days. Umblical port site infection (PSI) was noted in 20 (7.9%). Conclusion; High frequency of umblical port site infection was noted in our study among patients undergoing laparoscopic cholecystectomy without using gloves, so use of gloves is safe, cost effective and reduces related morbidities. Port site infection was significantly associated with increasing, gender, diabetes, residential status, prolonged duration of surgery and duration of hospitalization. Keywords; Umblical Port site infection, gloves, Laparoscopic cholecystectomy DOI : 10.7176/JMPB/54-13 Publication date : April 30 th 2019","PeriodicalId":16339,"journal":{"name":"Journal of Medicine, Physiology and Biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75302764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Postoperative complications such as surgical site infections, dehiscence, seromas, and hematomas prolong wound care and impose significant cost increases to patients and healthcare providers. Clinicians aiming to reduce the incidence of these complications should be aware of risk factors associated with surgical type, procedures used, patient characteristics, and postoperative care. Today, improved guidelines and general practices for managing surgical incisions have reduced the incidence of complications to historic lows. In addition to these standard care options, advanced wound care approaches have been extensively studied and exist as options for clinicians to provide adjunctive postoperative support and facilitate wound healing. These systems include advanced wound dressings and closed-incision negative-pressure therapy. Advanced wound care is not appropriate in all settings, and healthcare providers must assess each case for specific needs to be addressed by the available incision management plans. Emerging therapies that are intended to improve the continuum of postoperative care should continue to be evaluated in controlled clinical trials to determine their effectiveness under different circumstances and to support the creation of more robust guidelines for their use. DOI : 10.7176/JMPB/53-04 Publication date :March 31 st 2019
{"title":"Challenges and Management of Surgical Site Occurrences","authors":"Moalla Muzzafar, H. Noreen, M. Raouf","doi":"10.7176/jmpb/53-04","DOIUrl":"https://doi.org/10.7176/jmpb/53-04","url":null,"abstract":"Postoperative complications such as surgical site infections, dehiscence, seromas, and hematomas prolong wound care and impose significant cost increases to patients and healthcare providers. Clinicians aiming to reduce the incidence of these complications should be aware of risk factors associated with surgical type, procedures used, patient characteristics, and postoperative care. Today, improved guidelines and general practices for managing surgical incisions have reduced the incidence of complications to historic lows. In addition to these standard care options, advanced wound care approaches have been extensively studied and exist as options for clinicians to provide adjunctive postoperative support and facilitate wound healing. These systems include advanced wound dressings and closed-incision negative-pressure therapy. Advanced wound care is not appropriate in all settings, and healthcare providers must assess each case for specific needs to be addressed by the available incision management plans. Emerging therapies that are intended to improve the continuum of postoperative care should continue to be evaluated in controlled clinical trials to determine their effectiveness under different circumstances and to support the creation of more robust guidelines for their use. DOI : 10.7176/JMPB/53-04 Publication date :March 31 st 2019","PeriodicalId":16339,"journal":{"name":"Journal of Medicine, Physiology and Biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72774131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background; Malaria which is potentially life threatening disease that is spread by protozoan parasites. Malaria yet remains to be a important public health concern among most of the endemic regions of world. There are 5 most common human species of plasmodium referred as “Plasmodium falciparum, P. vivax, P. ovale, P. knowlesi, and P. malariae” which can spread the disease. The major complications are caused by P. falciparum and P. vivax, with P. falciparum being the more virulent. This study was conducted to determine the frequency of plasmodium falciparum among patients with uncomplicated malaria in our population. Objective; To determine the frequency of Plasmodium vivax in patients with uncomplicated malaria. Study Design; Descriptive, Cross-sectional study. Setting; Department of Medicine, Nishtar Hospital, Multan. Results; Of these study cases, 93 (56.4 %) were male patients while 72 (43.6%) were female patients. Mean age of our study cases was noted to be 35.52 ± 10.39 years. Majority of our study cases i.e. 101 (61.2%) were from rural areas while 64 (38.8%) were from urban areas, 129 (78.2%) were poor and 65 (39.4%) had positive history of using anti – malarial drugs. Mean duration of disease was 4.37 ± 2.82 days and majority of our patients i.e. 107 (64.8%) had disease duration up to 5 days. Plasmodium vivax was diagnosed in 129 (78.2%) patients. Conclusion; High frequency of plasmodium vivax was noted in our study, among patients with uncomplicated malaria. Plasmodium vivax was significantly associated with female gender and previous use of anti–malarial drugs. Keywords; plasmodium falciparum, malaria, plasmodium vivax. DOI : 10.7176/JMPB/55-11 Publication date :May 31 st 2019
{"title":"FREQUENCY OF PLASMODIUM VIVAX IN PATIENTS HAVING UNCOMPLICATED MALARIA.","authors":"A. Tareen, A. Bari, S. Saleem","doi":"10.7176/jmpb/55-11","DOIUrl":"https://doi.org/10.7176/jmpb/55-11","url":null,"abstract":"Background; Malaria which is potentially life threatening disease that is spread by protozoan parasites. Malaria yet remains to be a important public health concern among most of the endemic regions of world. There are 5 most common human species of plasmodium referred as “Plasmodium falciparum, P. vivax, P. ovale, P. knowlesi, and P. malariae” which can spread the disease. The major complications are caused by P. falciparum and P. vivax, with P. falciparum being the more virulent. This study was conducted to determine the frequency of plasmodium falciparum among patients with uncomplicated malaria in our population. Objective; To determine the frequency of Plasmodium vivax in patients with uncomplicated malaria. Study Design; Descriptive, Cross-sectional study. Setting; Department of Medicine, Nishtar Hospital, Multan. Results; Of these study cases, 93 (56.4 %) were male patients while 72 (43.6%) were female patients. Mean age of our study cases was noted to be 35.52 ± 10.39 years. Majority of our study cases i.e. 101 (61.2%) were from rural areas while 64 (38.8%) were from urban areas, 129 (78.2%) were poor and 65 (39.4%) had positive history of using anti – malarial drugs. Mean duration of disease was 4.37 ± 2.82 days and majority of our patients i.e. 107 (64.8%) had disease duration up to 5 days. Plasmodium vivax was diagnosed in 129 (78.2%) patients. Conclusion; High frequency of plasmodium vivax was noted in our study, among patients with uncomplicated malaria. Plasmodium vivax was significantly associated with female gender and previous use of anti–malarial drugs. Keywords; plasmodium falciparum, malaria, plasmodium vivax. DOI : 10.7176/JMPB/55-11 Publication date :May 31 st 2019","PeriodicalId":16339,"journal":{"name":"Journal of Medicine, Physiology and Biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80994993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background; Laparoscopic cholecystectomy is one of the commonly performed surgical procedure these days which is associated with significant reduction of morbidities and mortality. This study was conducted to ascertain complications in acute pancreatitis. Objective; To determine the frequency of complications of early cholecystectomy in patients with acute pancreatitis. Material and Methods; A total 152 patients with acute pancreatitis were enrolled in our study who underwent early laparoscopic cholecystectomy and were followed to document complications. All the data was entered and analyzed using SPSS-18. Results; Of these 152 study cases, 57 (37.5 %) were male patients while 95 (62.5 %) were female patients. Mean age of our study cases was 37.25 ± 7.29 years Of these 152 study cases, 71 (46.7 %) belonged to rural areas and 81 (53.3 %) belonged to urban areas. Diabetes was present in 40 (26.3 %) of our study cases. Hypertension was present in 67 (44.1%) of our study cases. Mean body mass index of our study cases was 26.12 ± 1.83 kg/m 2 and obesity was present in 39 (25.7 %) of our study cases. Mean duration of surgery was 58.53 ± 12.48 minutes and 77 (50.7%) had duration of surgery more than 60 minutes. Mean hospital stay was 5.23 ± 2.36 days and 80 (52.6%) had duration of hospital stay for more than 4 days. Complications were noted in 29 (19.1%) of our study cases. Conclusion; Early laparoscopic cholecystectomy in patients with acute pancreatitis is quite safe, reliable and effective procedure as frequency of complications was low in our study cases. Complication were significantly associated with increasing gender, age, diabetes and hypertension. All the surgeons treating such patients should employ early cholecystectomy to achieve desired outcomes. Keywords; Complication, Acute pancreatitis, Cholecystectomy. DOI : 10.7176/JMPB/54-14 Publication date : April 30 th 2019
{"title":"ASSOCIATION OF EARLY CHOLECYSTECTOMY WITH COMPLICATIONS IN PATIENTS PRESENTING WITH ACUTE PANCREATITIS.","authors":"Muhammad Shahbaz, M. Aqeel, Abdul Hadi","doi":"10.7176/jmpb/54-14","DOIUrl":"https://doi.org/10.7176/jmpb/54-14","url":null,"abstract":"Background; Laparoscopic cholecystectomy is one of the commonly performed surgical procedure these days which is associated with significant reduction of morbidities and mortality. This study was conducted to ascertain complications in acute pancreatitis. Objective; To determine the frequency of complications of early cholecystectomy in patients with acute pancreatitis. Material and Methods; A total 152 patients with acute pancreatitis were enrolled in our study who underwent early laparoscopic cholecystectomy and were followed to document complications. All the data was entered and analyzed using SPSS-18. Results; Of these 152 study cases, 57 (37.5 %) were male patients while 95 (62.5 %) were female patients. Mean age of our study cases was 37.25 ± 7.29 years Of these 152 study cases, 71 (46.7 %) belonged to rural areas and 81 (53.3 %) belonged to urban areas. Diabetes was present in 40 (26.3 %) of our study cases. Hypertension was present in 67 (44.1%) of our study cases. Mean body mass index of our study cases was 26.12 ± 1.83 kg/m 2 and obesity was present in 39 (25.7 %) of our study cases. Mean duration of surgery was 58.53 ± 12.48 minutes and 77 (50.7%) had duration of surgery more than 60 minutes. Mean hospital stay was 5.23 ± 2.36 days and 80 (52.6%) had duration of hospital stay for more than 4 days. Complications were noted in 29 (19.1%) of our study cases. Conclusion; Early laparoscopic cholecystectomy in patients with acute pancreatitis is quite safe, reliable and effective procedure as frequency of complications was low in our study cases. Complication were significantly associated with increasing gender, age, diabetes and hypertension. All the surgeons treating such patients should employ early cholecystectomy to achieve desired outcomes. Keywords; Complication, Acute pancreatitis, Cholecystectomy. DOI : 10.7176/JMPB/54-14 Publication date : April 30 th 2019","PeriodicalId":16339,"journal":{"name":"Journal of Medicine, Physiology and Biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85821671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background; The prevalence of thyroid disease is likely increased among chidren with celiac disease (CD). In addition, exposure to gluten-free treatment may be associated with a risk of thyroid disease, but this association remains controversial. Objective; To Determine the frequency of Prolonged breastfeeding in children with celiac disease at a tertiary care hospital. Material and Methods; Children with celiac disease (as given in operational definition) were enrolled and their mothers was inquired regarding history of breastfeeding in their child. All the data was entered and analyzed using SPSS-18. Results; Of these 160 study cases, 67 (41.9 %) were male patients while 93 (58.1 %) were female patients. Mean age of our study cases was 51.19 ± 11.25 months (with minimum age of our study cases was 12 months while maximum age was 60 months). Of these 160 study cases, 92 (57.5 %) belonged to rural areas and 68 (42.5 %) belonged to urban areas. Monthly family income up to Rs. 35000 was noted in 68 (42.5%) while more than Rs. 35000 was noted in 92 (57.5%) of our study cases. Mean disease duration of celiac disease was 5.23 ± 4.21 months and 117 (73.1%) had disease duration up to 6 months. Mean duration of breastfeeding was 18.23 ± 5.43 months and prolonged breastfeeding was noted in 124 (77.5%). Conclusion; Prolonged breastfeeding frequency was poor in children with celiac disease in our study. Prolonged breastfeeding was significantly associated with age, disease duration, ethnicity and maternal literacy. A mass campaign to create awareness regarding benefits of breastfeeding should be launched at national electronic and print media. Clinicians treating children having celiac disease should educate the mothers for breastfeeding benefits so as to decrease disease morbidity which will save them future hardships and improve quality of life of such patients. Keywords; Celiac Disease, Breastfeeding, Prolonged. DOI : 10.7176/JMPB/54-19 Publication date : April 30 th 2019
{"title":"PROTECTIVE ROLE OF BREASTFEEDING IN CHILDREN WITH CELIAC DISEASE.","authors":"S. Tariq, M. Arshad, G. Iqbal","doi":"10.7176/jmpb/54-19","DOIUrl":"https://doi.org/10.7176/jmpb/54-19","url":null,"abstract":"Background; The prevalence of thyroid disease is likely increased among chidren with celiac disease (CD). In addition, exposure to gluten-free treatment may be associated with a risk of thyroid disease, but this association remains controversial. Objective; To Determine the frequency of Prolonged breastfeeding in children with celiac disease at a tertiary care hospital. Material and Methods; Children with celiac disease (as given in operational definition) were enrolled and their mothers was inquired regarding history of breastfeeding in their child. All the data was entered and analyzed using SPSS-18. Results; Of these 160 study cases, 67 (41.9 %) were male patients while 93 (58.1 %) were female patients. Mean age of our study cases was 51.19 ± 11.25 months (with minimum age of our study cases was 12 months while maximum age was 60 months). Of these 160 study cases, 92 (57.5 %) belonged to rural areas and 68 (42.5 %) belonged to urban areas. Monthly family income up to Rs. 35000 was noted in 68 (42.5%) while more than Rs. 35000 was noted in 92 (57.5%) of our study cases. Mean disease duration of celiac disease was 5.23 ± 4.21 months and 117 (73.1%) had disease duration up to 6 months. Mean duration of breastfeeding was 18.23 ± 5.43 months and prolonged breastfeeding was noted in 124 (77.5%). Conclusion; Prolonged breastfeeding frequency was poor in children with celiac disease in our study. Prolonged breastfeeding was significantly associated with age, disease duration, ethnicity and maternal literacy. A mass campaign to create awareness regarding benefits of breastfeeding should be launched at national electronic and print media. Clinicians treating children having celiac disease should educate the mothers for breastfeeding benefits so as to decrease disease morbidity which will save them future hardships and improve quality of life of such patients. Keywords; Celiac Disease, Breastfeeding, Prolonged. DOI : 10.7176/JMPB/54-19 Publication date : April 30 th 2019","PeriodicalId":16339,"journal":{"name":"Journal of Medicine, Physiology and Biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78818552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Ignatov, Christos Drossinakis, R. Toshkova, E. Zvetkova, G. Gluhchev
Studies were conducted with model systems of influence of Drossinakis with electromagnetic (e.m.) fields and infrared thermal field (ITF) (Ignatov, Mosin, Niggli, Drossinakis, 2013). The purpose of research is to analyze effects over DNA. In the report is carried out analysis of effects over water and physiological saline. Results are achieved with blood serum of hamsters and physiological processes in hamsters with tumors. The analyses with water are conducted using the methods Nonequilibrium Energy Spectrum (NES) and Differential Nonequilibrium Energy Spectrum (DNES) (Antonov, 1992; Ignatov, 1998). Experiments are carried out with the influence of tumor cells of a mouse in water. It is observed reduction of DNES spectrum according to the control sample of cells in healthy animals. (Antonov, 1992). Reduction is also observed in DNES spectrum in blood serum of people having oncological diseases, compared to the one of healthy people (Ignatov, 2012). Such a reduction is most prevalent in (-0.1387 eV; 8.95 µm; 1117 cm -1 ). In research of the effects of e.m. fields in water and blood serum from hamsters the range is (-0.08 – -0.14 eV) (8.9 –15.5µm) (645–1129 cm -1 ). Research is conducted for the effects over Graffi tumor that was implanted in hamsters (Toshkova, Ignatov, Zvetkova, Ignatov, Gluhchev, Drossinakis, 2019). Studies are conducted with pH and oxidation redox potential (ORP) effects of e.m. fields over physiological saline (Gluhchev, Ignatov, Drossinakis, 2019). Keywords: Infrared thermal field (ITF), electromagnetic fields (e.m. fields), experimental Graffi solid tumor, energy spectrum, NES and DNES methods. DOI : 10.7176/JMPB/56-03 Publication date :May 31 st 2019
{"title":"Effects of Electromagnetic Fields over DNA in Tumor Diseases, Biophysical and Biochemical Model Systems","authors":"I. Ignatov, Christos Drossinakis, R. Toshkova, E. Zvetkova, G. Gluhchev","doi":"10.7176/jmpb/56-03","DOIUrl":"https://doi.org/10.7176/jmpb/56-03","url":null,"abstract":"Studies were conducted with model systems of influence of Drossinakis with electromagnetic (e.m.) fields and infrared thermal field (ITF) (Ignatov, Mosin, Niggli, Drossinakis, 2013). The purpose of research is to analyze effects over DNA. In the report is carried out analysis of effects over water and physiological saline. Results are achieved with blood serum of hamsters and physiological processes in hamsters with tumors. The analyses with water are conducted using the methods Nonequilibrium Energy Spectrum (NES) and Differential Nonequilibrium Energy Spectrum (DNES) (Antonov, 1992; Ignatov, 1998). Experiments are carried out with the influence of tumor cells of a mouse in water. It is observed reduction of DNES spectrum according to the control sample of cells in healthy animals. (Antonov, 1992). Reduction is also observed in DNES spectrum in blood serum of people having oncological diseases, compared to the one of healthy people (Ignatov, 2012). Such a reduction is most prevalent in (-0.1387 eV; 8.95 µm; 1117 cm -1 ). In research of the effects of e.m. fields in water and blood serum from hamsters the range is (-0.08 – -0.14 eV) (8.9 –15.5µm) (645–1129 cm -1 ). Research is conducted for the effects over Graffi tumor that was implanted in hamsters (Toshkova, Ignatov, Zvetkova, Ignatov, Gluhchev, Drossinakis, 2019). Studies are conducted with pH and oxidation redox potential (ORP) effects of e.m. fields over physiological saline (Gluhchev, Ignatov, Drossinakis, 2019). Keywords: Infrared thermal field (ITF), electromagnetic fields (e.m. fields), experimental Graffi solid tumor, energy spectrum, NES and DNES methods. DOI : 10.7176/JMPB/56-03 Publication date :May 31 st 2019","PeriodicalId":16339,"journal":{"name":"Journal of Medicine, Physiology and Biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77918664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Proper nutrition may reverse the malnutrition and can modulate renal function in hemodialysis patients. In majority of the dialysis units in Pakistan, nutritional advice is given by health professionals working in dialysis. We compared the impact of dietary counseling by a renal dietitian, on nutritional status with that by health professionals working in dialysis units in patients undergoing maintenance hemodialysis. Nutritional assessments were made using subjective global assessment (SGA) scale, which combines assessment of intake, physical findings, and functional status. Two hundred and seventy‑seven patients undergoing hemodialysis from two renal care units in Hayatabad Medical Complex Peshawar and Lahore Gernal Hospital Lahore Pakistan, were enrolled (138 patients in control group, 139 in experimental group). In the experimental group, patients were given repeated dietary counseling by a renal dietician, whereas control group patients were provided with the necessary nutritional information by another health professional. Detailed nutritional, biochemical, and SGA assessment were done on all of them at the beginning and completion of study after 6 months. Patients were categorized as well‑nourished (WN) (SGA = 1–14), mild to moderate malnourishment (MMM) (SGA = 15–35), and severe malnutrition (SM) (SGA = 36–49). In the present study, the overall malnutrition rate at baseline was 95.3%, and it dropped down to 91.7% after 6 months after nutritional counseling. In the experimental group, malnutrition status decreased from 97.2% to 89.8%, whereas in the control group, malnutrition situation remained same. Compared to baseline, in the control group, there was no improvement in the WN group. However, a shift has been observed from MMM group to SM group suggesting more number of patients are becoming malnourished. Contrarily, in the experimental group, an improvement of +7.2% in WN group and +14.3% in MMM group and a drop of −21.6% in severe malnourished group suggesting more number of patients gaining nutrition. The present study observed a significant improvement in nutritional status of patients who received counseling by the renal dietician. The reduction in SGA score was independent of reductions in serum creatinine and blood urea levels Keywords : Dietary Counselling, Nutritional Status, Hemodialysis Patients DOI : 10.7176/JMPB/55-16 Publication date :May 31 st 2019
{"title":"Impact of Dietary Counselling to Improve Nutritional Status of Hemodialysis Patients","authors":"S. Razaq, Khudija Nayab, A. Mirza","doi":"10.7176/jmpb/55-16","DOIUrl":"https://doi.org/10.7176/jmpb/55-16","url":null,"abstract":"Proper nutrition may reverse the malnutrition and can modulate renal function in hemodialysis patients. In majority of the dialysis units in Pakistan, nutritional advice is given by health professionals working in dialysis. We compared the impact of dietary counseling by a renal dietitian, on nutritional status with that by health professionals working in dialysis units in patients undergoing maintenance hemodialysis. Nutritional assessments were made using subjective global assessment (SGA) scale, which combines assessment of intake, physical findings, and functional status. Two hundred and seventy‑seven patients undergoing hemodialysis from two renal care units in Hayatabad Medical Complex Peshawar and Lahore Gernal Hospital Lahore Pakistan, were enrolled (138 patients in control group, 139 in experimental group). In the experimental group, patients were given repeated dietary counseling by a renal dietician, whereas control group patients were provided with the necessary nutritional information by another health professional. Detailed nutritional, biochemical, and SGA assessment were done on all of them at the beginning and completion of study after 6 months. Patients were categorized as well‑nourished (WN) (SGA = 1–14), mild to moderate malnourishment (MMM) (SGA = 15–35), and severe malnutrition (SM) (SGA = 36–49). In the present study, the overall malnutrition rate at baseline was 95.3%, and it dropped down to 91.7% after 6 months after nutritional counseling. In the experimental group, malnutrition status decreased from 97.2% to 89.8%, whereas in the control group, malnutrition situation remained same. Compared to baseline, in the control group, there was no improvement in the WN group. However, a shift has been observed from MMM group to SM group suggesting more number of patients are becoming malnourished. Contrarily, in the experimental group, an improvement of +7.2% in WN group and +14.3% in MMM group and a drop of −21.6% in severe malnourished group suggesting more number of patients gaining nutrition. The present study observed a significant improvement in nutritional status of patients who received counseling by the renal dietician. The reduction in SGA score was independent of reductions in serum creatinine and blood urea levels Keywords : Dietary Counselling, Nutritional Status, Hemodialysis Patients DOI : 10.7176/JMPB/55-16 Publication date :May 31 st 2019","PeriodicalId":16339,"journal":{"name":"Journal of Medicine, Physiology and Biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82757776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Objective of study was to assess the inflammation in obstructive sleep apnea syndrome patients by using platelet lymphocyte ratio and relationship between platelet lymphocyte ratio and severity of obstructive sleep apnea. Study Design: Cross sectional study Place and Duration: Pulmonology department of Nishtar Hospital Multan and Jinnah Hospital, Lahore from June 2018 to March 2019. Methods: This cross sectional study was conducted in Pulmonology department of Nishtar Hospital Multan from June 2016 to March 2017.Total 280 patients were selected by non-probability consecutive sampling. All patients underwent whole night polysomnography. Patients were divided into control group (AHI 30) according to their AHI score. Numerical variables like age, body mass index, white cell count, platelets, hemoglobin (Hb) and platelet lymphocyte ratio were statistically analyzed by mean and standard deviation and t-test applied to assess their significance. Qualitative variables like gender and smoking status were statistically analyzed by frequency and percentage. Chi square test was applied to check the significance. P value <0.05 was regarded as significant. Results: Platelet lymphocyte ratio was significantly raised in patients with obstructive sleep apnea syndrome. There was significant correlation between platelet lymphocyte ratio and AHI (p<0.05). So study showed that there was significant association between obstructive sleep apnea syndrome severity (represented by AHI) and systemic inflammation (represented by PLR). Significant differences were found between age (p =0.000), ESR (p =0.000), CRP (p =0.003), Cholesterol (p =0.000), Platelets (p =0.048), Hb (p =0.000), PLR (p =0.000) and white blood cells (p =0.000), in groups. Association was found between gender (p =0.000) and smoking status (p =0.030) in groups. So, gender and smoking were the effect modifiers. Conclusion: the observations of our study suggest that Platelet lymphocyte ratio was significantly raised in patients with obstructive sleep apnea syndrome. There was significant correlation between platelet lymphocyte ratio and AHI (p<0.05). So study showed that there was significant association between obstructive sleep apnea syndrome severity (represented by AHI) and systemic inflammation (represented by PLR). Key words: Obstructive sleep apnea syndrome, Platelet lymphocyte ratio, polysomnography DOI : 10.7176/JMPB/54-08 Publication date : April 30 th 2019
{"title":"Relationship of platelet-lymphocyte ratio with severity of obstructive sleep apnea syndrome.","authors":"Zeeshan Anjum, Sana Maqsood, Sehrish Saeed","doi":"10.7176/jmpb/54-08","DOIUrl":"https://doi.org/10.7176/jmpb/54-08","url":null,"abstract":"Objective: Objective of study was to assess the inflammation in obstructive sleep apnea syndrome patients by using platelet lymphocyte ratio and relationship between platelet lymphocyte ratio and severity of obstructive sleep apnea. Study Design: Cross sectional study Place and Duration: Pulmonology department of Nishtar Hospital Multan and Jinnah Hospital, Lahore from June 2018 to March 2019. Methods: This cross sectional study was conducted in Pulmonology department of Nishtar Hospital Multan from June 2016 to March 2017.Total 280 patients were selected by non-probability consecutive sampling. All patients underwent whole night polysomnography. Patients were divided into control group (AHI 30) according to their AHI score. Numerical variables like age, body mass index, white cell count, platelets, hemoglobin (Hb) and platelet lymphocyte ratio were statistically analyzed by mean and standard deviation and t-test applied to assess their significance. Qualitative variables like gender and smoking status were statistically analyzed by frequency and percentage. Chi square test was applied to check the significance. P value <0.05 was regarded as significant. Results: Platelet lymphocyte ratio was significantly raised in patients with obstructive sleep apnea syndrome. There was significant correlation between platelet lymphocyte ratio and AHI (p<0.05). So study showed that there was significant association between obstructive sleep apnea syndrome severity (represented by AHI) and systemic inflammation (represented by PLR). Significant differences were found between age (p =0.000), ESR (p =0.000), CRP (p =0.003), Cholesterol (p =0.000), Platelets (p =0.048), Hb (p =0.000), PLR (p =0.000) and white blood cells (p =0.000), in groups. Association was found between gender (p =0.000) and smoking status (p =0.030) in groups. So, gender and smoking were the effect modifiers. Conclusion: the observations of our study suggest that Platelet lymphocyte ratio was significantly raised in patients with obstructive sleep apnea syndrome. There was significant correlation between platelet lymphocyte ratio and AHI (p<0.05). So study showed that there was significant association between obstructive sleep apnea syndrome severity (represented by AHI) and systemic inflammation (represented by PLR). Key words: Obstructive sleep apnea syndrome, Platelet lymphocyte ratio, polysomnography DOI : 10.7176/JMPB/54-08 Publication date : April 30 th 2019","PeriodicalId":16339,"journal":{"name":"Journal of Medicine, Physiology and Biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89632881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Arshad, Khawaja Muhammad Afnan, Moiz Hassan Azdee
Objective; To determine the frequency of in – hospital mortality in atrial fibrillation patients having ischemic stroke at a tertiary care hospital. Study design; Cross-sectional study. Setting; Department of Medicine, Nishtar Hospital, Multan. Material and methods; All the cases of ischemic stroke having atrial fibrillation (171), fulfilling inclusion criteria was recruited from indoor and outdoor of Department of General Medicine, Nishtar Hospital Multan from May 2018 to May 2019. These patients were investigated for the presence of atrial fibrillation, diabetes, hypertension, smoking and obesity and data was analyzed by SPSS version 18. Results; A total of 171 patients with ischemic stroke having atrial fibrillation were taken. Of these 171 patients, 112 (65.5%) were male patients while 59 (34.5%) were female patients. Mean age of our patients was 58.32 ± 12.06 years, ranging from 41 to 81 years while 54 (31.6%) were aged up to 50 years and 119 (69.6%) were aged more than 50 years. Of these 171 patients, 52 (30.4%) were from rural and 119 (69.6%) from urban areas, 87 (50.9%) belonged to poor families and 84 (49.1%) belonged to middle income families. Sixty-six (38.6%) were diabetic and 106 (62%) were hypertensive. Mean body mass index was 25.39 ± 3.81 kg/m 2 with obesity was present in 46 (26.9%) while 66 (38.6%) were smokers and all smokers were male patients. Mortality was noted in 72 (42.1%) in ischemic stroke patients having atrial fibrillation. Conclusion; Frequency of mortality was high in our study among patients with ischemic stroke having atrial fibrillation. Mortality was significantly associated with male gender, smoking. diabetes, hypertension and obesity. Keywords; Ischemic stroke, atrial fibrillation, risk factors. DOI : 10.7176/JMPB/55-06 Publication date :May 31 st 2019
{"title":"ATRIAL FIBRILLATION AS A PREDICTOR OF IN-HOSPITAL MORTALITY IN PATIENTS WITH ISCHEMIC STROKE.","authors":"M. Arshad, Khawaja Muhammad Afnan, Moiz Hassan Azdee","doi":"10.7176/jmpb/55-06","DOIUrl":"https://doi.org/10.7176/jmpb/55-06","url":null,"abstract":"Objective; To determine the frequency of in – hospital mortality in atrial fibrillation patients having ischemic stroke at a tertiary care hospital. Study design; Cross-sectional study. Setting; Department of Medicine, Nishtar Hospital, Multan. Material and methods; All the cases of ischemic stroke having atrial fibrillation (171), fulfilling inclusion criteria was recruited from indoor and outdoor of Department of General Medicine, Nishtar Hospital Multan from May 2018 to May 2019. These patients were investigated for the presence of atrial fibrillation, diabetes, hypertension, smoking and obesity and data was analyzed by SPSS version 18. Results; A total of 171 patients with ischemic stroke having atrial fibrillation were taken. Of these 171 patients, 112 (65.5%) were male patients while 59 (34.5%) were female patients. Mean age of our patients was 58.32 ± 12.06 years, ranging from 41 to 81 years while 54 (31.6%) were aged up to 50 years and 119 (69.6%) were aged more than 50 years. Of these 171 patients, 52 (30.4%) were from rural and 119 (69.6%) from urban areas, 87 (50.9%) belonged to poor families and 84 (49.1%) belonged to middle income families. Sixty-six (38.6%) were diabetic and 106 (62%) were hypertensive. Mean body mass index was 25.39 ± 3.81 kg/m 2 with obesity was present in 46 (26.9%) while 66 (38.6%) were smokers and all smokers were male patients. Mortality was noted in 72 (42.1%) in ischemic stroke patients having atrial fibrillation. Conclusion; Frequency of mortality was high in our study among patients with ischemic stroke having atrial fibrillation. Mortality was significantly associated with male gender, smoking. diabetes, hypertension and obesity. Keywords; Ischemic stroke, atrial fibrillation, risk factors. DOI : 10.7176/JMPB/55-06 Publication date :May 31 st 2019","PeriodicalId":16339,"journal":{"name":"Journal of Medicine, Physiology and Biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87252848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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