Prashant Sharma, Chander Hans, Rahul Saini, M. Sachdeva, A. Khadwal, P. Bose, R. Das
{"title":"Bone marrow erythroblastic dysplasia on morphology correlates significantly with flow cytometric apoptosis and peripheral blood eryptosis","authors":"Prashant Sharma, Chander Hans, Rahul Saini, M. Sachdeva, A. Khadwal, P. Bose, R. Das","doi":"10.4103/jmau.jmau_97_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_97_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70802010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral cysticercosis: Importance of early diagnosis and prevention","authors":"Sheetal Choudhari, Kamlesh Dekate, SnehaMasne Deshpande, Snehal Dhumal","doi":"10.4103/jmau.jmau_8_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_8_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70802071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new insight into the classification of clear cell lesions of the oral cavity based on the diagnostic modalities used – A review","authors":"AAlagu Vennila, RebekahChibborah Prabakaran, Narayanarao Gururaj, Alka Kale, SDeenul Fathima, MK Keerthik Lavanya, M Nandhini","doi":"10.4103/jmau.jmau_75_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_75_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135319792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/jmau.jmau_122_22
A. Elsamanoudy, Ahmed Alzahrani, DeemA Alblaihed, DoaaY Jamal, ShimaaT Ibrahim, Ghada A Ajabnoor
{"title":"The potential use of salivary OMICs in understanding the pathogenesis and diagnosis of oral and medical diseases","authors":"A. Elsamanoudy, Ahmed Alzahrani, DeemA Alblaihed, DoaaY Jamal, ShimaaT Ibrahim, Ghada A Ajabnoor","doi":"10.4103/jmau.jmau_122_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_122_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70800268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relation of osteopontin expression to tumor-associated macrophages-derived transforming growth factor beta 1 expression in non-small cell lung carcinoma","authors":"Marwa Abd El-Azeem, Shaimaa M. M. Bebars","doi":"10.4103/jmau.jmau_7_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_7_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70801646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Giant Placental Chorioangioma in a Young Patient Causing Adverse Fetal Outcome","authors":"Sonal Sharma, Shagun Wadhwa, Sonali Dixit","doi":"10.4103/jmau.jmau_71_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_71_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70801700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maxillary mucormycotic osteonecrosis as a manifestation of Post-COVID-19 infection in non-diabetic patients: Report of two cases","authors":"V Vasanthi, ThamizhanambiTamizh Paavai, Annasamy Rameshkumar, Krishnan Rajkumar, VB Krishnakumar Raja, Veerabahu Muthusubramanian","doi":"10.4103/jmau.jmau_81_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_81_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135318724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Computational protein structural annotations of Mycobacterium tuberculosis thiamine phosphate pyrophosphorylase","authors":"FatenAhmad Alsulaimany","doi":"10.4103/jmau.jmau_59_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_59_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135319791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heba M Hussein, Nagwa El-Nefiawy, Haidy F Abdel Hamid, Marwa A Moneim
Introduction: This study was done to assess the injurious effects of omeprazole by an in vivo experimental study on rat kidneys.
Materials and methods: Forty-two adult male albino rats were divided into four groups: Control group (I) in which rats were not administrated any treatment. In Groups IIa, IIb, and IIc rats received daily oral omeprazole in dose of 0.75 mg per kg for 2, 4, and 6 weeks, respectively. At the end of the experiment, blood samples were collected for serum creatinine and blood urea nitrogen measurement. Then, animals were sacrificed, and kidney specimens were processed for paraffin blocks, sectioned and stained with H and E, Mallory trichrome and Periodic acid-Schiff, then examined by the light microscope. Stained sections and image analysis were used to count vacuolated cells, pyknotic nuclei, tubular casts, and area percent of collagen fiber deposition, and then, data were subjected to the statistical analysis.
Results: Examination of omeprazole-treated groups showed injury of renal corpuscles, renal tubules, and vascular congestion with inflammatory cell infiltrate in renal interstitium. Thickening of basement membrane with deposition of collagen fibers was also detected. Statistically significant increase in the number of vacuolated cells, pyknotic nuclei, hyaline casts, and area percentage of collagen fiber deposition as compared with the control group was noticed, with deterioration of renal function tests.
Conclusion: It was concluded that the long-term use of omeprazole resulted in structural damage of rat renal tissue associated with deterioration of renal function in a time-dependent manner.
{"title":"Does Omeprazole, the Proton-Pump Inhibitor, Affects the Structure of the Kidney of Male Albino Rats? Histological and Laboratory Study.","authors":"Heba M Hussein, Nagwa El-Nefiawy, Haidy F Abdel Hamid, Marwa A Moneim","doi":"10.4103/jmau.jmau_11_21","DOIUrl":"https://doi.org/10.4103/jmau.jmau_11_21","url":null,"abstract":"<p><strong>Introduction: </strong>This study was done to assess the injurious effects of omeprazole by an <i>in vivo</i> experimental study on rat kidneys.</p><p><strong>Materials and methods: </strong>Forty-two adult male albino rats were divided into four groups: Control group (I) in which rats were not administrated any treatment. In Groups IIa, IIb, and IIc rats received daily oral omeprazole in dose of 0.75 mg per kg for 2, 4, and 6 weeks, respectively. At the end of the experiment, blood samples were collected for serum creatinine and blood urea nitrogen measurement. Then, animals were sacrificed, and kidney specimens were processed for paraffin blocks, sectioned and stained with H and E, Mallory trichrome and Periodic acid-Schiff, then examined by the light microscope. Stained sections and image analysis were used to count vacuolated cells, pyknotic nuclei, tubular casts, and area percent of collagen fiber deposition, and then, data were subjected to the statistical analysis.</p><p><strong>Results: </strong>Examination of omeprazole-treated groups showed injury of renal corpuscles, renal tubules, and vascular congestion with inflammatory cell infiltrate in renal interstitium. Thickening of basement membrane with deposition of collagen fibers was also detected. Statistically significant increase in the number of vacuolated cells, pyknotic nuclei, hyaline casts, and area percentage of collagen fiber deposition as compared with the control group was noticed, with deterioration of renal function tests.</p><p><strong>Conclusion: </strong>It was concluded that the long-term use of omeprazole resulted in structural damage of rat renal tissue associated with deterioration of renal function in a time-dependent manner.</p>","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"11 1","pages":"23-33"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/28/5e/JMAU-11-23.PMC10153739.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9470948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/jmau.jmau_103_22
Vinaya Rudresh, Suchetha Aghanashini, S. Srirangarajan, P. Srikumar, Ravi J Rao, B. Upasana
{"title":"A novel ultrastructural morphological characterization of platelet-rich fibrin among diabetics","authors":"Vinaya Rudresh, Suchetha Aghanashini, S. Srirangarajan, P. Srikumar, Ravi J Rao, B. Upasana","doi":"10.4103/jmau.jmau_103_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_103_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70799449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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