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Genetic Technologies: Textbook 基因技术:教科书
Pub Date : 2024-01-08 DOI: 10.35825/2587-5728-2023-7-3-299-300
M. V. Supotnitskiy
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引用次数: 0
Epidemiology of Camelpox: New Aspects 骆驼毒的流行病学:新的方面
Pub Date : 2024-01-08 DOI: 10.35825/2587-5728-2023-7-3-248-260
L. F. Stovba, V. N. Lebedev, O. V. Chukhralia, A. L. Khmelev, S. L. Kuznetsov, S. Borisevich
After the abolition of the mandatory smallpox vaccination, the humanity lost the immunity not only to smallpox, but also to infections caused by pathogens of this family (Orthopoxvirus): monkeypox, cowpox, buffalo pox, camelpox. Since the camelpox and African gerbil viruses are the closest to the variola virus (genomic homology is 97%) in phylogenetic and genetic terms, it cannot be ruled out that a mutation in a small fragment of the genome of one of these viruses will lead to the replacement of a relatively safe virus with an epidemically dangerous pathogen. The purpose of is article is to summarize materials on the study of camelpox virus. The sources for this research is scientific articles and other English-language literature available via the Internet. The research method is an analysis of scientific sources on camelpox from the general to the specific. The authors considered the epizootic danger of the virus, its virulence for humans, phylogenetic relationship with other orthopoxviruses, means of specific prevention and treatment of camel pox in camels. The discussion and the results. The causative agent of camelpox causes a nodular-pastular rash on the skin and mucous membranes in Camelus dromedaries and Camelus bactrianus. The disease is contagious, and its epizootics lead to significant economic damage. From December 2008 to May 2009, several laboratory-confirmed cases of camelpox in humans were reported in India, Somalia and eastern Sudan. Nowadays for the identification of the camelpox virus, a RT-PCR test system with primers for the C18L gene is usually offered, which detects only this virus. The established host range of the virus is limited to one animal - the camel. To treat sick camels, chemotherapy drugs are used: cidofovir and tocoverimate (ST-246). For immunoprophylaxis, live and inactivated vaccines are used. The conclusion. Camelpox virus poses a risk to humans in regions where people raise camels and are in close contact with them. The immunodeficient populations of people may serve as an additional «window» for the penetration of this virus into human society. The genetic variability of the virus and the plasticity of its genome make it possible to obtain virus strains with altered properties. Synthetic biology methods create a risk, through small substitutions in the genome of the virus, of turning it into an epidemic danger for humans. Constant monitoring of this disease is necessary, since there is a danger of the transmission of camelpox from Kazakhstan to areas bordering the Russian Federation.
取消天花疫苗强制接种后,人类不仅失去了对天花的免疫力,还失去了对该科病原体(正痘病毒)引起的感染的免疫力:猴痘、牛痘、水痘、驼痘。由于驼痘病毒和非洲沙鼠病毒在系统发育和遗传学方面与水痘病毒最为接近(基因组同源性为 97%),因此不能排除其中一种病毒基因组小片段的突变会导致相对安全的病毒被具有流行危险的病原体所取代。本文旨在总结有关骆驼蓬病毒研究的材料。这项研究的资料来源是科学文章和互联网上的其他英文文献。研究方法是从总体到具体分析有关驼痘的科学资料。作者考虑了该病毒的流行危险性、对人类的致病力、与其他正痘病毒的系统发育关系、骆驼痘的具体预防和治疗方法。讨论和结果。骆驼痘的病原体会在单峰骆驼和双峰骆驼的皮肤和粘膜上引起结节状皮疹。该病具有传染性,其流行会造成重大经济损失。2008 年 12 月至 2009 年 5 月,印度、索马里和苏丹东部报告了几例实验室确诊的人类骆驼痘病例。目前,在鉴定驼痘病毒时,通常会使用一种 RT-PCR 测试系统,该系统使用 C18L 基因引物,只能检测出驼痘病毒。该病毒的宿主范围仅限于一种动物--骆驼。为治疗患病骆驼,可使用化疗药物:西多福韦(cidofovir)和托卡维尔(tocoverimate)(ST-246)。免疫预防则使用活疫苗和灭活疫苗。结论在有人饲养骆驼并与骆驼密切接触的地区,驼痘病毒对人类构成威胁。免疫缺陷人群可能是这种病毒渗入人类社会的另一个 "窗口"。病毒的基因变异性及其基因组的可塑性使人们有可能获得特性发生改变的病毒株。合成生物学方法通过对病毒基因组进行微小的置换,有可能使病毒对人类造成流行性威胁。有必要对这一疾病进行持续监测,因为驼痘有可能从哈萨克斯坦传播到与俄罗斯联邦接壤的地区。
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引用次数: 0
Ensuring the Possibility of Using a Standard Set of Filter Gas Masks in an Isolating Protection Mode 确保在隔离保护模式下使用一套标准过滤气体面罩的可能性
Pub Date : 2024-01-08 DOI: 10.35825/2587-5728-2023-7-3-286-298
A. Y. Kovalev, S. B. Blinov, S. A. Tkachenko, M. P. Shabelnikov, O. A. Kulazhin
Combined type personal respiratory protection equipment, combining the functions of air purification and complete isolation from the environment, has not received significant development due to the complexity of the design, which limits their use. At the same time, as the accumulated experience of the actions of rescue military units of the civil defense forces, the Ministry of Emergency Situations of the Russian Federation and units of the radiation, chemical and biological protection troops of the Armed Forces of the Russian Federation shows, the use of combined type protective equipment in a number of cases is extremely necessary. The purpose of the work is to develop the design of a universal module connected to a filter gas mask to enable the implementation of a mode of complete isolation from the ambient air. Materials and methods. The justification for the design of the universal module was carried out on the basis of existing developments of design and circuit solutions for units and elements of the filter gas mask and self-contained breathing apparatus. Predictive assessment of the performance of the design of the removable module components was carried out by calculation in the Microsoft Excel 2013 environment using methods of aero- and hydrodynamic calculations of technological systems. The functionality of the main structural units of the module was tested in laboratory conditions while simulating the parameters of human external respiration. The discussion of the results. The following tasks were solved: the technical characteristics of the universal module were substantiated, ensuring the preservation of the indicators of the main protective, operational and ergonomic properties of filter gas masks and the design of the universal module with a predictive assessment of the performance of its main components; a physical model of the universal module was made; An experimental test of the performance of its main structural components was carried out. Conclusion. The results obtained confirmed the operability of the design and circuit solutions of the universal module, which ensures the implementation of a mode of complete isolation from ambient air in a standard set of filter gas masks.
兼具空气净化和与环境完全隔离功能的组合式个人呼吸防护设备,由于设计复杂, 限制了其使用,因此没有得到重大发展。同时,正如民防部队救援军事单位、俄罗斯联邦紧急情况部和俄罗斯联邦武装部队辐射、化学和生物防护部队积累的行动经验所表明的那样,在许多情况下使用组合型防护设备是极为必要的。这项工作的目的是开发设计一种与过滤式防毒面具连接的通用模块,以实现与环境空气完全隔离的模式。材料和方法。通用模块的设计依据是过滤式防毒面具和自给式呼吸器的单元和元件的现有设计和电路解决方案。通过在 Microsoft Excel 2013 环境中使用技术系统的空气和流体力学计算方法进行计算,对可拆卸模块组件的设计性能进行了预测评估。模块主要结构单元的功能在实验室条件下进行了测试,同时模拟了人体外部呼吸的参数。结果讨论。完成了以下任务:证实了通用模块的技术特性,确保过滤式防毒面具的主要保护、操作和人体工程学特性指标得以保留,并在设计通用模块时对其主要部件的性能进行了预测性评估;制作了通用模块的物理模型;对其主要结构部件的性能进行了实验测试。结论。所获得的结果证实了通用模块的设计和电路解决方案的可操作性,这确保了在一套标准过滤防毒面具中实现与环境空气完全隔离的模式。
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引用次数: 0
Nuclear War as It Looks 核战争的原貌
Pub Date : 2024-01-08 DOI: 10.35825/2587-5728-2023-7-3-205-235
M. V. Supotnitskiy
Currently, there are practically no people left who have seen the consequences of the use of nuclear weapons. This is the reason for certain frivolous statements about the advisability of using tactical nuclear weapons to solve certain tactical problems. The purpose of this work is to remind, using the example of the consequences of the atomic bombings of the cities of Hiroshima and Nagasaki, how does the nuclear war looks like in reality. Materials and Methods. Open sources from the Cold War era and more recent reviews of the consequences of the use of nuclear weapons were analyzed. The analysis was carried out from general to specific, i.e. from the understanding of physical processes underlying a nuclear explosion and determining the design of the nuclear devices, to the specific consequences of their use. Discussion. The article analyses the history of the creation of the «Gadget», «Fat Man» and «Kid» bombs, their design, preparation and the results of the use. Detailed descriptions of nuclear explosions and the consequences of their use, made both by those who used nuclear weapons and by those against whom they were used, are provided. Being imperfect in design and ineffective in using fissile matter, they showed stunning power even for the present time, destroying two densely populated cities and at least 106 thousand people at once. Real examples show the features of the destruction of engineering objects and the impact on people of the damaging factors of a nuclear explosion. Attention is drawn to the fact that the power of the bombs used was 15 and 22 kt, respectively. According to modern NATO classification, these are tactical nuclear weapons. It is designed to destroy targets in the tactical depth of enemy troop deployment (up to 300 km). The maximum power of tactical ammunition according to NATO standards is up to 100 kt. It means that the yield of the tactical ammunition used in battle will depend on the tactical mission, and not be limited to a few kilotons. Conclusions. The use of tactical nuclear weapons without escalating their power, causing large casualties among the population and the risk of being drawn into a global nuclear war is impossible. Currently, the world is oversaturated with nuclear and thermonuclear weapons. Some countries possess them secretly, others have the potential to create such weapons. Therefore, any use of nuclear weapons by anyone will lead to the lowering of the threshold of nuclear deterrence. It will become a common thing during the resolution of military conflicts.
目前,几乎没有人见过使用核武器的后果。这就是某些人轻率地说使用战术核武器解决某些战术问题是明智之举的原因。这项工作的目的是以广岛和长崎两市遭受原子弹轰炸的后果为例,提醒人们核战争在现实中是什么样子的。材料与方法。分析了冷战时期的公开资料以及最近对使用核武器后果的评论。分析从一般到具体进行,即从了解核爆炸的基本物理过程和确定核装置的设计,到使用核武器的具体后果。讨论。文章分析了 "小玩意"、"胖子 "和 "小鬼 "炸弹的制造历史、设计、准备和使用结果。使用核武器的人和被使用核武器的人都对核爆炸及其后果进行了详细描述。尽管在设计上并不完美,在使用裂变物质方面也不奏效,但即使在当代,它们也显示出了惊人的威力,一次就摧毁了两个人口稠密的城市和至少 10.6 万人。真实的例子显示了工程物体被摧毁的特点以及核爆炸的破坏因素对人类的影响。需要注意的是,所用炸弹的威力分别为 15 千吨和 22 千吨。根据北约的现代分类,这些是战术核武器。其目的是摧毁敌方部队部署战术纵深(最远 300 公里)内的目标。根据北约标准,战术弹药的最大威力可达 100 kt。这意味着战斗中使用的战术弹药的当量将取决于战术任务,而不限于几千吨。结论。使用战术核武器而不使其威力升级、不造成大量人员伤亡、不面临被卷入全球核战争的风险是不可能的。目前,世界上的核武器和热核武器已经过度饱和。一些国家秘密拥有核武器,另一些国家则有可能制造核武器。因此,任何人使用核武器都会降低核威慑的门槛。在解决军事冲突的过程中,这将成为一件司空见惯的事情。
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引用次数: 0
Reaction Pathways of Oxidative Transformation of the Radioprotector Quercetin 辐射防护剂槲皮素氧化转化的反应途径
Pub Date : 2024-01-08 DOI: 10.35825/2587-5728-2023-7-3-237-247
V. V. Olicheva, A. D. Titova, I. R. Ilyasov, V. N. Fateenkov, A. V. Braun
Quercetin is one of the most promising natural polyphenolic radioprotective compounds. This property is based on its radical-scavenging activity and high antioxidant capacity, in the manifestation of which the products of oxidative degradation of quercetin play a significant role. The formation of specific metabolites during the oxidation of quercetin can determine not only its radioprotective properties, but also toxic manifestations. The purpose of this article is to summarize previously obtained data regarding the reaction pathways of oxidative transformation of quercetin. Materials and methods. We used publicly available scientific publications dedicated to the study of quercetin transformation processes. The method of analysis is descriptive. The discussion of the results. A review of scientific works dedicated to oxygen oxidation, radical-initiated oxidation, electrochemical and enzymatic oxidation is presented, possible transformation products of quercetin and the mechanisms of their formation are given. The most characteristic oxidation pathways of quercetin are determined by the chemical structure of the rings, which exhibit specific reactivity. The influence of the solvent composition on the oxidation products during the autoxidation of quercetin was revealed, while the radical and electrochemical models of oxidation differ in the presence of polymer adducts. Once in a living organism, quercetin can bind free radicals, thereby preventing the harmful effects of radiation, that is, it has the properties of a radioprotector. Conclusions. Quercetin can be considered as a potential radioprotector due to its ability to bind free radicals formed in the biological fluids of living organisms exposed to radiation.
槲皮素是最有前途的天然多酚辐射防护化合物之一。这一特性基于其自由基清除活性和高抗氧化能力,而槲皮素的氧化降解产物在其中发挥了重要作用。槲皮素氧化过程中形成的特定代谢物不仅能决定其辐射防护特性,还能决定其毒性表现。本文旨在总结之前获得的有关槲皮素氧化转化反应途径的数据。材料和方法。我们使用了公开发表的专门研究槲皮素转化过程的科学出版物。分析方法是描述性的。结果讨论。综述了专门研究氧氧化、自由基引发的氧化、电化学氧化和酶促氧化的科学著作,给出了槲皮素可能的转化产物及其形成机理。槲皮素最有特征的氧化途径是由环的化学结构决定的,这些环具有特定的反应活性。研究揭示了槲皮素自氧化过程中溶剂成分对氧化产物的影响,而在聚合物加合物存在的情况下,自由基氧化和电化学氧化模式也有所不同。槲皮素一旦进入生物体内,就能与自由基结合,从而防止辐射的有害影响,即具有辐射防护剂的特性。结论由于槲皮素能与暴露在辐射中的生物体的生物液体中形成的自由基结合,因此可被视为一种潜在的辐射防护剂。
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引用次数: 0
Medical Consequences and Treatment of Injuries Caused by White Phosphorus Munitions 白磷弹药造成伤害的医疗后果和治疗方法
Pub Date : 2024-01-08 DOI: 10.35825/2587-5728-2023-7-4-276-285
J. Lakota
White phosphorus (WP) has been used in hand grenades, mortar and artillery shells, and aerial bombs since World War I. Recently it has been used in combat operations in Iraq, Syria, Afghanistan, Yemen, Nagorno-Karabakh and is used during the Palestinian-Israeli conflict in Gaza. Burns caused by WP usually result in death or disability. The purpose of the work is to analyze and summarize the data of the scientific literature on the medical consequences and treatment of lesions caused using ammunition with WP. Materials and methods. For the analysis, we used available scientific publications describing the consequences of WP burns received during hostilities. The method of analysis is descriptive. The following tasks were solved: the properties of WP as a damaging agent were studied; materials on the medical consequences of WP lesions and methods of treatment of such lesions were summarized. Discussion of the results. WP is highly reactive, highly toxic and ignites in air as early as 35°C. The severity of WP lesions is the result of both the thermal and chemical effects of combustion. Fatalities among humans from WP burns have occurred involving less than 10% of the total body surface area. Burns caused by WP heal more slowly than thermal burns. WP penetrates deeply through the fatty subcutaneous tissue. Therefore, the burns are full-thick, necrotic. The absorbed WP acts as a cellular poison and causes damage to the central nervous system, liver, kidneys, myocardium, and other organs. Any WP particles trapped in the wound may re-ignite. Conclusion. At the pre-hospital stage, the first thing to do is to wash off the wounds with cool water and remove the pieces of WP that have fallen into the skin with forceps. The light from the UV lamp can help to visualize the small particles of WP. Cleaning exfoliated skin and removing visible WP particles from the skin are critical methods for limiting wound severity and systemic WP absorption. It is advisable to excise the burned area within an hour after the lesion and repeat surgical procedures until all phosphorus particles have been removed; to control during the first 48 hours for the content of calcium and phosphorus in the blood serum with appropriate correction. In the future, skin grafting and treatment with allogeneic mesenchymal stem cells are advisable.
自第一次世界大战以来,白磷(WP)一直被用于手榴弹、迫击炮弹、炮弹和航空炸弹中。最近,白磷被用于伊拉克、叙利亚、阿富汗、也门、纳戈尔诺-卡拉巴赫的作战行动中,并在加沙的巴以冲突中使用。可湿性粉剂造成的烧伤通常会导致死亡或残疾。这项工作的目的是分析和总结有关使用可湿性粉剂弹药造成的医疗后果和治疗方法的科学文献数据。材料和方法。为了进行分析,我们使用了现有的描述敌对行动中可湿性粉剂烧伤后果的科学出版物。分析方法是描述性的。我们完成了以下任务:研究了可湿性粉剂作为一种破坏性制剂的特性;总结了有关可湿性粉剂灼伤的医学后果和治疗此类灼伤的方法的资料。结果讨论。可湿性粉剂具有高反应性和剧毒性,在 35°C 的空气中即可点燃。可湿性粉剂病变的严重程度是燃烧的热效应和化学效应共同作用的结果。因可湿性粉剂烧伤致死的人数不到体表总面积的 10%。可湿性粉剂烧伤的愈合速度比热烧伤慢。可湿性粉剂会深入皮下脂肪组织。因此,烧伤是全厚坏死性的。吸收的可湿性粉剂可作为细胞毒物,对中枢神经系统、肝脏、肾脏、心肌和其他器官造成损害。伤口中残留的可湿性粉剂微粒可能会再次燃烧。结论在入院前阶段,首先要做的是用凉水冲洗伤口,并用镊子取出掉入皮肤的可湿性粉剂碎片。紫外线灯的光线有助于观察可湿性粉剂的小颗粒。清洁脱落的皮肤和清除皮肤上可见的可湿性粉剂颗粒是限制伤口严重程度和全身可湿性粉剂吸收的关键方法。建议在皮损发生后一小时内切除烧伤部位,并重复手术操作,直至磷颗粒全部清除;在最初的 48 小时内控制血清中钙和磷的含量,并进行适当的纠正。今后,最好进行皮肤移植和异体间充质干细胞治疗。
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引用次数: 0
Armor Piercing Projectiles Based on Depleted Uranium and the Consequences of Their Use for the Environment and People 贫铀穿甲弹及其使用对环境和人类的影响
Pub Date : 2023-08-04 DOI: 10.35825/2587-5728-2023-7-1-6-23
Российская Федерация, проезд Энтузиастов
   The intention of the collective West to supply the armed forces of Ukraine with armor-piercing shells with cores (penetrators) made of depleted uranium (DU), is changing the situation in the zone of special military operation (SVO). A new damaging factor is introduced into combat operations – uranium-238 (238U), one of the longest-lived natural radioactive isotopes of uranium.   The purpose of the review is to identify the signs and consequences of the use of armor-piercing projectiles based on depleted uranium.   Materials and research methods. The sources available through the PubMed, Google Scholar and Russian Electronic Library databases were analyzed.   Research results. NATO uses DU in 20-, 25-, 30-, 105-, 120- and 140-mm caliber projectiles. The cores are made from recycled DU, which is a waste from the production of nuclear weapons. Due to man-made isotopes, it is more radioactive than DU from natural uranium. When such a projectile hits an armored object, a large amount of respirable radioactive and toxic dust of black uranium oxides, small fragments and fragments of the penetrator, remaining in the armored vehicles and around it, is formed. One 120 mm projectile produces approximately 950 g of black dust. Almost 99 % of the internal dose received by the military will come from alpha particles, the most dangerous to health. Projectiles that miss their targets sink deep into the soil, their penetrators corrode for decades, releasing soluble uranium compounds into underground water sources. In areas where DU shells were used, mass diseases of «unexplained etiology» are observed among military personnel and civilians, reducing their life expectancy and fertility.   Discussion of results and conclusions. The first signs of the use of shells with DU, which can be installed on the battlefield: round holes in the armor of tanks and the presence of solid black dust around them and in the tank itself. In case of fires in the warehouses of such shells, due to other oxidation conditions, crumbling yellow dust is formed. When examining it, it is necessary to pay attention to the presence of elevated concentrations of 236U. The fact that a soldier was hit by DU can be confirmed by the presence of uranium in his urine. The use of DU shells on the territory of the Russian Federation, in terms of its consequences for people and nature, is the use of radiological weapons, a disguised form of nuclear warfare. And it must be treated accordingly.
西方集体向乌克兰武装部队提供贫铀弹芯(穿甲弹)的意图正在改变特种军事行动区的局势。一种新的破坏因素被引入到作战行动中——铀-238 (238U),铀的天然放射性同位素中寿命最长的一种。审查的目的是查明使用贫铀穿甲弹的迹象和后果。材料和研究方法。通过PubMed、Google Scholar和俄罗斯电子图书馆数据库进行分析。研究的结果。北约在20毫米、25毫米、30毫米、105毫米、120毫米和140毫米口径炮弹中使用DU。核心是由回收的贫铀制成的,贫铀是核武器生产中的废物。由于有人造同位素,它的放射性比天然铀中的贫铀更强。当这种弹丸击中装甲物体时,会在装甲车辆及其周围形成大量可吸入的放射性和有毒的黑色氧化铀粉尘、小碎片和穿甲弹碎片。一枚120毫米的炮弹产生大约950克的黑尘。军队接受的内部剂量中,几乎99%来自对健康最危险的α粒子。没有击中目标的炮弹会深入土壤,它们的穿透体会被腐蚀几十年,释放出可溶性的铀化合物,进入地下水源。在使用贫铀炮弹的地区,在军事人员和平民中观察到"原因不明"的大规模疾病,减少了他们的预期寿命和生育能力。讨论结果和结论。使用带有DU的炮弹的第一个迹象,可以安装在战场上:坦克装甲上的圆孔,以及它们周围和坦克本身存在的固体黑尘。此类炮弹仓库发生火灾时,由于其他氧化条件,形成破碎的黄尘。检查时,有必要注意是否存在高浓度的236U。一个士兵被贫铀击中的事实可以通过他尿液中铀的存在来证实。在俄罗斯联邦领土上使用贫铀弹,就其对人民和自然造成的后果而言,是使用放射性武器,一种变相的核战争。我们必须相应地对待它。
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引用次数: 0
International Terrorism Using Toxic Chemicals as an Element of Hybrid Warfare 国际恐怖主义使用有毒化学品作为混合战争的要素
Pub Date : 2023-08-04 DOI: 10.35825/2587-5728-2023-7-1-36-52
E. N. Glotov, V. P. Kotov, I. Lozanov, M. L. Makarov, О. М. Nikitin, А. М. Fleyer, N. I. Shilo
   Modern terrorism is a complex system that consists of a complex of complementary processes – ideological, criminal, military, political, religious and nationalistic. Chemical terrorism is one of the elements of hybrid warfare – a new technology in the fight for the reorganization of the world at the present stage.   The purpose of this article is to consider one of the elements of hybrid wars – chemical terrorism.   Sources and informational basis of the research, methodology. In this work, the sources published by the Organization for the Prohibition of Chemical Weapons (OPCW) were used. The publications available through the databases PubMed, Google Scholar, eLibrary, etc. were also studied. Research method – system analysis. The probability of the use of chemical warfare agents and toxic chemicals by terrorists of various ideological orientations as part of a hybrid war strategy has been studied.   The discussion of the results. Hybrid military conflicts of a non-classical nature involve the participation of international terrorist organizations in hostilities. The Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and on Their Destruction (CWC) does not explicitly prohibit non-state actors from obtaining and using chemical weapons. This situation is very convenient for the states that have signed the CWC and use terrorist organizations as part of the strategy of indirect action. In such cases the information and psychological operations are aimed at the collapse and fragmentation of countries, undermining their ability to resist, discrediting their leaders, and causing a split in the ranks of the allies. This was most clearly shown in the incidents with the use of toxic chemicals in Syria.   Conclusion. Working groups under the auspices of the UN and the OPCW, sent to Syria to investigate incidents with the use of sarin, proved unable to conduct objective investigations. They usually ended up on the side of the sponsors of chemical terrorist attacks, despite the evidence of falsification. This, in turn, can lead to serious military conflicts, for which the role of casus belli will be played by false news from the global media. The only mechanism that made it possible to stop such provocations in Syria was a public warning from the Russian side about the place and time of the planned false flag attack. At the same time, such a selective position of the UN and the OPCW can at any moment lead to the loss of the control over chemical weapons in certain regions of the world.
现代恐怖主义是一个复杂的系统,由意识形态、犯罪、军事、政治、宗教和民族主义等相互补充的复杂过程组成。化学恐怖主义是混合战争的要素之一,是现阶段世界格局重组斗争中的一种新技术。本文的目的是考虑混合战争的要素之一-化学恐怖主义。研究的来源和信息依据、方法。在这项工作中,使用了禁止化学武器组织(禁化武组织)公布的资料来源。还研究了PubMed、Google Scholar、library等数据库中的出版物。研究方法——系统分析。研究了不同意识形态取向的恐怖分子作为混合战争战略的一部分使用化学战剂和有毒化学品的可能性。结果的讨论。非经典性质的混合军事冲突涉及国际恐怖组织参与敌对行动。《禁止发展、生产、储存和使用化学武器及销毁此种武器公约》并未明确禁止非国家行为体获取和使用化学武器。这种情况对签署《禁止化学武器公约》并利用恐怖组织作为间接行动战略的一部分的国家来说非常方便。在这种情况下,情报和心理战的目的是使国家崩溃和分裂,削弱其抵抗能力,败坏其领导人的信誉,并在盟国的队伍中造成分裂。这在叙利亚使用有毒化学品的事件中得到了最清楚的证明。结论。联合国和禁化武组织派出工作组前往叙利亚调查使用沙林毒气事件,但事实证明无法进行客观调查。他们通常站在化学恐怖袭击的发起者一边,尽管有伪造证据。这反过来又可能导致严重的军事冲突,全球媒体的虚假新闻将扮演战争原因的角色。唯一能够阻止这种挑衅的机制是俄罗斯方面公开警告计划中的假旗袭击的地点和时间。与此同时,联合国和禁化武组织的这种选择性立场随时可能导致世界某些地区失去对化学武器的控制。
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引用次数: 0
The Principal Trends of the Development of Flamethrower-incendiary Armament of Foreign Сountries 国外喷火器-燃烧武器发展的主要趋势Сountries
Pub Date : 2023-08-04 DOI: 10.35825/2587-5728-2023-7-1-62-72
V. Inozemtsev, N. B. Lopatina, L. B. Dolgova, D. Frolov, A. Meshcheryakov
   The lecture is intended for the improvement of the professional skills and knowledge of the students and graduates of military schools in the field of foreign flamethrower-incendiary armament. Two problems are considered in the lecture: 1) the principal trends of the development of incendiary ammunition of foreign countries; 2) the principal trends of the development of flamethrower-incendiary systems of foreign countries.
该讲座旨在提高军事院校学生和毕业生在外国火焰喷射器-燃烧武器领域的专业技能和知识。报告讨论了两个问题:1)国外燃烧弹药发展的主要趋势;2)国外喷火器燃烧系统发展的主要趋势。
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引用次数: 0
Typical Mistakes in Claims and Specifications of the Inventions in the NBC Protection Corps NBC保护兵团发明权利要求书和说明书中的典型错误
Pub Date : 2023-08-04 DOI: 10.35825/2587-5728-2023-7-1-73-81
M. V. Supotnitskiy
   The growth of inventive activity in the NBC Protection Troops is accompanied by an increase in requests for examination, leading to a delay in the process of considering patent applications at the Federal Institute of Industrial Property of Rospatent.   The aim of this work is to summarize the common mistakes in the claim and the Specifications of the inventions in the NBC Protection Troops.   Materials and research methods. Examination requests for applications for inventions were analyzed, for which positive decisions were eventually received, i. e. the delay in their consideration was not due to the lack of a technical solution. In the application materials, the most typical mistakes were identified and summarized with the references to regulatory documents. The provisions of these documents were explained in the text of the article and supported by references to the work of patent law specialists.   The results of the study. The main mistakes detected at the stage of formal examination are made in the application, description of drawings and in the claims. At the stage of substantive examination, the experts pay attention to the applicants' misunderstanding of the rules for drawing up the claims and sections of the description that substantiate the claims. The «Background of the Invention» section is usually presented in the form of a review, in which the closest analogue is not analyzed; the technical result is not indicated; examples revealing the implementation of the claimed invention are not complete.   Discussion of results and conclusions. Any mistakes detected at the stage of formal expertise can be easily corrected with careful attention to the preparation of application documents. The mistakes identified at the stage of substantive examination are of a systemic nature. They are based on the stereotypes of a specialist, who can not see patentable technical solutions and cannot plan them. It is possible to correct this situation by training young specialists in the field of legal protection and protection of inventions, utility models, industrial designs and methods of their use, even before they start their main activities. It is possible also to accompany such trainings with the study of the fundamentals of the Theory of Inventive Problem Solving. Patenting itself must be carried out within the framework of the organization's patent policy.
随着NBC保护部队的发明活动的增加,审查请求也在增加,导致俄罗斯专利局联邦工业产权局审议专利申请的过程出现延误。本工作的目的是总结NBC保护部队发明权利要求书和发明说明书中常见的错误。材料和研究方法。对发明申请的审查请求进行了分析,最终收到了肯定的决定,即延迟审议并非由于缺乏技术解决办法。在申报材料中,通过对规范性文件的参考,找出并总结了最典型的错误。这些文件的规定在文章的正文中作了解释,并引用了专利法专家的工作作为支持。研究的结果。在形式审查阶段发现的主要错误是在申请书、附图说明和权利要求书中。在实质审查阶段,专家关注申请人对权利要求书的起草规则和说明书中构成权利要求的部分的误解。“发明背景”部分通常以审查的形式呈现,其中不分析最接近的类似物;技术结果未注明;揭示所要求的发明的实施的示例不完整。讨论结果和结论。在正式专业知识阶段发现的任何错误都可以很容易地纠正,只要仔细注意准备申请文件。在实质审查阶段发现的错误是系统性的。它们是基于专家的刻板印象,他们看不到可获得专利的技术解决方案,也无法对其进行规划。纠正这种情况是可能的,办法是在青年专家开始其主要活动之前,对他们进行法律保护和保护发明、实用新型、工业设计及其使用方法方面的培训。这种培训也可以与创造性解决问题理论的基础学习相结合。申请专利本身必须在组织的专利政策框架内进行。
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引用次数: 0
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Journal of NBC Protection Corps
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