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Use of Modular and Wearable Technical Means of Disinfection During Liquidation of Emergency Situations 模块化和可穿戴式消毒技术手段在紧急情况清理中的应用
Pub Date : 2022-12-23 DOI: 10.35825/2587-5728-2022-6-4-365-371
In the process of liquidation of emergency situations of biological nature (ESBN) by the NBC Protection Corps of the Armed Forces of the Russian Federation, the modern modular and wearable technical means of disinfection based on an aerosol method of treatment of objects were widely used. The purpose of the work is to summarize experience of the use of modular and wearable technical means of disinfection during the liquidation of biological emergency. The most intensive use of mobile technical means of disinfection was carried out for more than two years in Chkalovsky airfield by the combined NBC protection group, which carried out work on the disinfection of aircraft of the Military Space Forces and the cargo transported by them against the pathogen of coronavirus infection. The main volume of work on disinfection of cargo compartments and cockpits of pilots of aircraft as well as cargo was performed in the aerosol method with the use of the following technical means: CDA (Aerosol Disinfection Complex) complex, the bagpack motorized and manual sprayers. The aerosol treatment method and the formulation based on ethyl alcohol provided high productivity of works, low manual labor costs, and reliable disinfection of objects with low consumption of preparation. Thus, the processing time of the cargo compartment of AN-124 aircraft with the help of autonomous modules of the CDA or backpack sprayers STIHL SR 450 did not exceed 20 minutes, and the consumption of the recipe was not more than 100 cm 3 ×m -2 . The use of modern modular and wearable disinfection means in the NBC protection units will ensure the increase of efficiency of disinfection measures in the interests of troops and population of the Russian Federation.
在俄罗斯联邦武装部队全国广播公司(NBC)保护部队清理生物紧急情况(ESBN)的过程中,广泛使用了基于气溶胶处理物体方法的现代模块化可穿戴消毒技术手段。本工作旨在总结生物突发事件清算过程中使用模块化、可穿戴式消毒技术手段的经验。在契卡洛夫斯基机场,联合全国广播公司保护小组开展了两年多的机动消毒技术手段最密集的工作,对军事航天部队的飞机及其运输的货物进行了冠状病毒感染病原体的消毒工作。采用气雾剂法对飞机货舱、驾驶员座舱及货物进行消毒,主要采用气雾剂消毒综合装置(CDA)、袋式电动和手动喷雾器等技术手段。该气溶胶处理方法和以乙醇为基础的配方具有工作生产率高、人工成本低、制剂消耗少、对物体消毒可靠等优点。因此,在CDA自主模块或背包喷射器STIHL SR 450的帮助下,AN-124飞机货舱的处理时间不超过20分钟,配方的消耗不超过100 cm 3 ×m -2。在NBC防护装置中使用现代模块化和可穿戴消毒手段,将确保提高消毒措施的效率,符合俄罗斯联邦部队和人口的利益。
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引用次数: 0
Modern High-Performance Methods for Special Processing of Arms, Military and Special Equipment 武器、军事和特种装备特种加工的现代高性能方法
Pub Date : 2022-09-27 DOI: 10.35825/10.35825/2587-5728-2022-6-3-271-281
Carrying out special treatment is one of the main measures to maintain the combat capability of troops in conditions of chemical and biological contamination or radiation contamination of the area.The purpose of the work was to assess the current state of the means of special processing of military equipment and to identify possible ways to improve their effectiveness. The existing means of special processing of military equipment basically meet the requirements, however, in modern conditions they have a number of shortcomings and need to be improved. Thus, aqueous solutions of degassing and disinfecting substances and organic formulations of special treatment are used with a relatively highconsumption rate of up to 4,5 l/m 2 and 0,6 l/m 2 , respectively, while the treatment time for 1 m 2 can be 1 minute, which is related as with the physicochemical properties of the solutions and formulations used, as well as with the features of the methods of their application. In addition, technical means of special processing are not intended for processing the internal volumes of military equipment, and preparatory measures require a set of tools. In the course of the analysis, it was found that a decreasein the consumption rate and an increase in the rate of special circulation can be achieved as a result of the use of foam concentrates that give a prolonging effect to aqueous solutions of chemically active substances. Increasing the automation and productivity of special processing of military equipment up to 30–40 units/h can be achieved as a result of the development of an in-line processing method. This method consists in applying degassing formulations to the treated surface in the form of an aerosol-droplet flow using centrifugal nozzles located on a semi-arched movable structure. At the same time, the increase in productivity is primarily achieved as a result of an increase in the simultaneouslyprocessed area of the object. Reducing the time for preliminary preparation of objects and increasing the completeness of measures for the special processing of military equipment can be achieved as a result of the development of a multi-stage method of degassing, disinfection and decontamination. The method consists in the successive application of high-pressure water jets and foam-forming or solvent formulations with a given treatment exposure time. In some cases, along with the treatmentof external surfaces, it becomes necessary to carry out degassing and disinfection of the internal habitable compartments of military equipment. One of the possible directions for solving this problem is a qualitative expansion of the capabilities of technical means of special treatment as a result of the development of a method for using ultra-small volumes of special treatment formulations in the form of a highly dispersed aerosol. It is advisable to spray solutions of chemically active substances by hydraulic or pneumohydraulic methods, while maintaining the main in
进行特殊处理是在受到化学、生物污染或辐射污染的地区保持部队作战能力的主要措施之一。这项工作的目的是评估军事装备的特殊加工手段的现状,并确定改进其效力的可能方法。现有的军事装备特殊加工手段基本满足了要求,但在现代条件下存在一些不足,需要改进。因此,使用脱气和消毒物质的水溶液和特殊处理的有机配方,其消耗率相对较高,分别可达4.5 l/ m2和0.6 l/ m2,而1 m2的处理时间可为1分钟,这与所使用的溶液和配方的物理化学性质以及它们的使用方法的特点有关。此外,特殊加工的技术手段并不打算用于加工军事装备的内部体积,而准备措施需要一套工具。在分析过程中发现,由于使用泡沫浓缩物,可以使化学活性物质的水溶液具有延长作用,因此可以降低消耗率并增加特殊循环率。通过开发一种在线加工方法,可以将军事装备特殊加工的自动化和生产率提高到30-40台/小时。该方法包括使用位于半拱形可移动结构上的离心喷嘴,以气溶胶-液滴流动的形式将脱气配方应用于处理表面。同时,生产率的提高主要是由于对象的同时加工面积的增加而实现的。由于开发了一种多阶段的脱气、消毒和去污方法,可以减少物品的初步准备时间,增加军事装备特殊加工措施的完整性。该方法包括在给定的处理曝光时间内连续应用高压水射流和泡沫形成或溶剂配方。在某些情况下,在处理外部表面的同时,有必要对军事装备的内部可居住隔间进行除气和消毒。解决这一问题的可能方向之一是,由于发展了一种以高度分散的气溶胶形式使用超小体积特殊处理配方的方法,从质量上扩大了特殊处理技术手段的能力。在保持配方质量的主要指标的同时,建议采用液压或气液压方法喷涂化学活性物质的溶液。使用所提出的特殊处理手段和方法将提高正在进行的脱气、消毒和去污措施的效率,因为它提高了生产率,降低了特殊处理溶液和配方的消耗率,提高了过程自动化程度,降低了劳动强度。
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引用次数: 0
New Chemical Weapons Destruction Technologies as the Key to SuccessfulCompletion of Chemical Weapons Disarmament Process 新的化学武器销毁技术是成功完成化学武器裁军进程的关键
Pub Date : 2022-09-27 DOI: 10.35825/10.35825/2587-5728-2022-6-3-213-228
Валерий Петрович Капашин, В.Г. Мандыч, И.Н. Исаев, И.В. Коваленко, В.Л. Верига
The fulfillment of international obligations of the Russian Federation under the Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and on Their Destruction required the development and the creation of safe innovative industrialtechnologies and facilities for the destruction of chemical weapons. The purpose of this work is to give brief characteristics of the technologies for the destruction of chemical weapons developed and commercially implemented at various facilities. The destruction of chemical weapons was carried out at seven facilities specially designed and built for this purpose. These facilities were located in six regions of the country. The choice of technologies for the destruction (utilization) of chemicalweapons was carried out on a competitive basis in the period from 1992 to 1995.The priority was given to the so-called two-stage technology. At the first stage, the toxic chemicals were extracted from the munitions or the containers and detoxified chemically in «soft» controlled conditions. Then the empty munitions were degassed. At the second stage, thermal neutralization or bituminization of the reaction masses was carried out with their subsequent burial. The two-stage technology for the destruction of mustard and mustard-lewisite mixtures was based on the interaction of toxic chemicals with an 80 ± 5% aqueous solution of monoethanolamine, which was supplied into the reactor at a temperature of 60–80 °C in the ratio toxic chemical: degassing formulation - 1:1.2 according to mass. The detoxification process was considered completed if the content of toxic chemicals in the reaction mass did not exceed 3,2×10 -3 %. To destroy lewisite, a «short scheme» in a jet-type reactor was implemented. The mixing of the initial reagents, lewisite and 20% alkali solution, was carried out using a nozzle of a special design, where lewisite was swirled with a special device (swirler) and supplied into the reactor. The first stage of the destruction of V-gases was carried out in munitions cases. The munitions were considered as chemical reactors. The process of detoxification of V-gases was considered completed when the residual content of toxic chemicals was at the level of 5×10 -4 %, and the reaction mass was delivered for thermal neutralization (second stage). In total, 39966,588 tons of toxic chemicals were destroyed. The whole number of destroyed containers with agents and chemical munitions amounted to 4,158,456 units. On September 27, 2017, the last chemical weapon was destroyed at the Kizner chemical weapons destruction facility, thus completing the process of complete destruction of chemical weapons stockpiles in the Russian Federation.
为履行俄罗斯联邦根据《关于禁止发展、生产、储存和使用化学武器及销毁此种武器的公约》所承担的国际义务,必须发展和创造用于销毁化学武器的安全、创新的工业技术和设施。这项工作的目的是简要介绍在各种设施开发和商业化实施的销毁化学武器的技术的特点。化学武器的销毁工作是在为此目的专门设计和建造的七个设施进行的。这些设施位于该国的六个区域。1992年至1995年期间,销毁(利用)化学武器的技术选择是在竞争的基础上进行的。优先考虑的是所谓的两阶段技术。在第一阶段,从弹药或容器中提取有毒化学品,并在“软”受控条件下进行化学解毒。然后对空弹药进行除气。在第二阶段,对反应质量进行热中和或沥青化,随后将其掩埋。两段式破坏芥菜和芥菜-路易斯酸混合物的技术是基于有毒化学物质与80±5%的单乙醇胺水溶液的相互作用,在60-80°C的温度下,按质量按有毒化学物质:脱气配方- 1:12 .2的比例供应到反应器中。如果反应质量中有毒化学物质的含量不超过3,2×10 - 3%,则认为解毒过程完成。为了摧毁路易斯核,在喷射式反应堆中实施了一个“短方案”。初始试剂路易斯酸盐和20%碱溶液的混合使用特殊设计的喷嘴进行,其中路易斯酸盐用特殊装置(旋流器)旋转并送入反应器。销毁v -气体的第一阶段是在弹药箱中进行的。这些弹药被认为是化学反应堆。当有毒化学物质残留量达到5×10 - 4%时,认为v气体解毒过程完成,并将反应质量交付热中和(第二阶段)。销毁有毒化学品39966588吨。销毁的装有药剂和化学弹药的集装箱总数达4 158 456个单位。2017年9月27日,最后一枚化武在基兹纳化武销毁设施被销毁,从而完成了俄罗斯联邦境内化武库存的彻底销毁进程。
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引用次数: 0
Ricin and Abrin as Possible Agents of Bioterror 蓖麻毒素和蓖麻毒素可能是生物恐怖分子
Pub Date : 2022-09-27 DOI: 10.35825/10.35825/2587-5728-2022-6-3-243-257
Plant toxins – ricin and abrin, obtained in a purified form from the beans of the castor bean and Abrus precatorius respectively, are considered by Western experts as potential damaging agents of a biological nature. The purpose of this work is to consider the danger of using ricin and abrin asagents of biological terrorism, as well as to assess the existing approaches and means for identifying these toxins, treating the intoxication caused by them, as well as the level of development of vaccine preparations. Both toxins have a similar molecular structure and mechanism of action. They consist of two subunits – A and B, resistant to high temperatures and extreme pH values. The mechanism of their damaging action is based on irreversible inhibition of the process of protein synthesis. The LD 50 of ricin for humans, according to various sources, is 3 μg/kg for inhalation and intravenous intake, 22–25 μg/kg for enteral intake, and about 500 μg/kg for subcutaneous intake. Abrin is moretoxic than ricin, with an LD 50 for humans ranging from 0.1 μg/kg to 1 μg/kg depending on the route of entry. In case of enteral poisoning with ricin and abrin, the victims develop symptoms of gastroenteritis within a few hours: nausea, vomiting and pain in the abdominal cavity and chest,diarrhea. Bleeding from various parts of the gastrointestinal tract may be present. In future, general intoxication symptoms (headache, weakness, fever) and symptoms of multiple organ damage (acute renal failure and acute liver failure) develop. In the terminal stage, symptoms of vascular shock and vascular collapse are expressed. Death usually occurs on the third day or later. Cases of the use of ricin and abrin for criminal and terrorist purposes are described in the article. The main approaches and modern means of indication, means of treating ricin and abrine intoxication, as well as the state of development of vaccine preparations are shown. The given data show that the danger of these toxins as damaging agents is underestimated in Russia. It is necessary to develop diagnostic test systems that allow early detection of intoxication with plant toxins in the affected and the toxins themselves on environmental objects, as well as specific means for the treatment and prevention ofacute poisoning with ricin and abrin.
植物毒素——蓖麻毒素和蓖麻毒素,分别从蓖麻和Abrus precatorius中提纯得到,被西方专家认为是潜在的生物性破坏剂。这项工作的目的是考虑使用蓖麻毒素和蓖麻毒素作为生物恐怖主义剂的危险,并评估现有的识别这些毒素、治疗由它们引起的中毒的方法和手段,以及疫苗制剂的发展水平。这两种毒素具有相似的分子结构和作用机制。它们由两个亚基- A和B组成,耐高温和极端pH值。它们的破坏作用机制是基于对蛋白质合成过程的不可逆抑制。根据各种来源,蓖麻毒素对人体的ld50为吸入和静脉摄入3 μg/kg,肠内摄入22-25 μg/kg,皮下摄入约500 μg/kg。蓖麻毒素的毒性比蓖麻毒素更强,人体的ld50根据进入途径的不同在0.1 μg/kg到1 μg/kg之间。在蓖麻毒素和蓖麻毒素肠内中毒的情况下,受害者会在几个小时内出现胃肠炎的症状:恶心、呕吐、腹腔和胸部疼痛、腹泻。可能出现胃肠道各部位出血。以后,一般中毒症状(头痛、虚弱、发热)和多器官损害症状(急性肾功能衰竭和急性肝功能衰竭)出现。终末期表现为血管休克和血管塌陷的症状。死亡通常发生在第三天或更晚。文章中描述了将蓖麻毒素和蓖麻毒素用于犯罪和恐怖主义目的的案例。介绍了蓖麻毒素和蓖麻毒素中毒的主要途径和现代指征、治疗方法以及疫苗制剂的发展状况。这些数据表明,在俄罗斯,这些毒素作为破坏剂的危险性被低估了。有必要开发诊断测试系统,以便及早发现受影响的植物毒素中毒和毒素本身对环境物体的中毒,以及治疗和预防蓖麻毒素和蓖麻毒素中毒的具体手段。
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引用次数: 0
Biological Laboratories in the Caucasus Region as Sources of Threats to Russia's National Security 高加索地区的生物实验室是对俄罗斯国家安全的威胁来源
Pub Date : 2022-09-27 DOI: 10.35825/10.35825/2587-5728-2022-6-3-258-270
В.В. Филонов, В.В. Щеренко, Ю.Е. Попов, В.Э. Терещатов
Currently, dozens of biological laboratories controlled by the US Department of Defense are deployed along the perimeter of the Russian Federation. They are operating in a closed regime and completely excluded from the jurisdiction of the states on whose territory they are located. The purpose of this work is to summarize the available information on the activities of these biolabs, controlled by the US Department of Defense in the Caucasus region. The deployment of these biolabs under theUS control in the Caucasus region is due to its favorable geographical position – in the north it borders the Russian Federation, and in the south – Iran. In addition, people of various ethnic groups (about 50) live compactly in the Caucasus region in various climatic conditions and in diverse areas.These circumstances make it possible to develop bioagents of various ethnic orientations. All these biolabs are «dual-use» facilities that are part of the US-controlled biosecurity system. They allow the US Department of Defense to solve the following tasks: to create and test a new generation of biological weapons; to collect information on endemic biopathogens, ways of distribution and means of combating them in the Russian Federation; to control the biological situation on the territory of the Russian Federation; to carry out military biological research without fear of protests from the American public; to create dangerous pathogens and genetic weapons; to conduct tests of biological agents on humans, tracking their virulence, delivery routes, probable mortality of the population and livestock; to circumvent international agreements and conventions on the control of bioweapons; to carry out biosabotage aimed at destroying the personnel of the Armed Forces and the populationof Russia, causing damage to the economy of our country by destroying livestock, infecting grain crops and discrediting Russian agricultural products on world markets. These US-controlled biolabs deployed along the perimeter of the Russian Federation threaten the national security of Russia and the countries in which they are located. Serious diplomatic efforts are needed to curtail their activities in the Caucasus region.
目前,美国国防部控制的数十个生物实验室部署在俄罗斯联邦的周边地区。他们在一个封闭的制度下运作,完全被排除在其领土所在国家的管辖范围之外。这项工作的目的是总结在高加索地区由美国国防部控制的这些生物实验室活动的现有信息。在高加索地区部署这些在美国控制下的生物实验室是由于其有利的地理位置- -其北部与俄罗斯联邦接壤,南部与伊朗接壤。此外,不同民族的人(约50人)在不同的气候条件和不同的地区紧密地生活在高加索地区。这些情况使得开发不同种族的生物制剂成为可能。所有这些生物实验室都是“两用”设施,是美国控制的生物安全系统的一部分。它们允许美国国防部解决以下任务:创造和测试新一代生物武器;收集关于俄罗斯联邦境内地方性生物病原体、传播方式和防治方法的资料;控制俄罗斯联邦领土上的生物状况;开展军事生物研究而不必担心美国公众的抗议;制造危险病原体和基因武器;对人类进行生物制剂试验,追踪其毒力、传递途径以及人口和牲畜的可能死亡率;规避控制生物武器的国际协定和公约;进行生物破坏,目的是摧毁俄罗斯武装部队人员和俄罗斯人民,通过破坏牲畜、感染粮食作物和破坏俄罗斯农产品在世界市场上的信誉来破坏我国的经济。这些美国控制的生物实验室部署在俄罗斯联邦周边,威胁着俄罗斯及其所在国家的国家安全。需要认真的外交努力来限制它们在高加索地区的活动。
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引用次数: 0
Modular Protective Materials Neutralizing Toxins (Organophosphorus Compounds and Mycotoxins) and Exhibiting Biocidity to Gram-positive and Gram-negative Bacterial Cells 模块化保护材料中和毒素(有机磷化合物和真菌毒素),并对革兰氏阳性和革兰氏阴性细菌细胞表现出生物杀灭性
Pub Date : 2022-09-27 DOI: 10.35825/10.35825/2587-5728-2022-6-3-229-242
Earlier we have developed the principle of constructing modular materials with desired properties. The aim of this work is to study the possibility of imparting bactericidal protective properties to modular materials (tissues). The experimental studies have demonstrated the possibility of combining modules containing metal carboxylates, metal nanoparticles, and enzyme nanocomplexes for multiple functionalization of the same fibrous material and/or fiber. Fibrous materials, as a result of successive application of modular formulations containing nanosized metals and enzyme nanocomplexes, to their surface acquired biocidal and antichemical protective properties. It has been established that the spray method of applying modules to the surface of the studied materials ismore universal, since aerosol application makes it possible to apply liquid to any wetted material with a uniform surface layer. The bactericidal properties depended on the chosen method of fibrous material functionalization. The obtained modular fibrous materials also showed good biocatalytic characteristics with respect to various organophosphorus compounds and mycotoxins. The duration of the effect of self-disinfection and self-degassing of fibrous materials treated with modular formulations containing nanosized metals and enzyme nanocomplexes is at least 230 days. The developed materials and the method of their production can be used both in obtaining completelynew fabrics for personal protective equipment and in developing new organizational, technical and methodological approaches to ensuring personal protection of personnel of the Armed Forces of the Russian Federation.
早些时候,我们已经开发了构建具有所需性能的模块化材料的原理。这项工作的目的是研究赋予模块化材料(组织)杀菌保护性能的可能性。实验研究表明,将含有金属羧酸盐、金属纳米颗粒和酶纳米复合物的模块组合在一起,可以实现同一纤维材料和/或纤维的多重功能化。纤维材料,由于连续应用含有纳米金属和酶纳米复合物的模块化配方,在其表面获得了生物杀灭和抗化学保护性能。已经确定,将模块应用于所研究材料表面的喷雾方法更为普遍,因为气溶胶应用可以将液体应用于具有均匀表面层的任何湿材料。其杀菌性能取决于纤维材料功能化方法的选择。所制得的模块化纤维材料对各种有机磷化合物和真菌毒素也表现出良好的生物催化特性。用含有纳米金属和酶纳米复合物的模块化配方处理的纤维材料的自消毒和自脱气效果的持续时间至少为230天。所开发的材料及其生产方法既可用于获得用于个人防护装备的全新面料,也可用于开发新的组织、技术和方法方法,以确保俄罗斯联邦武装部队人员的人身保护。
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引用次数: 1
Sources of Ionizing Radiation Used in Modern and Advanced NBC Reconnaissance Devices (Lecture) 现代和先进NBC侦察设备中使用的电离辐射源(讲座)
Pub Date : 2022-09-07 DOI: 10.35825/10.35825/2587-5728-2022-6-3-282-294
Э.В. Васильковский, А.В. Дикун, И.Г. Васюкевич
The lecture is intended to prepare students studying under an additional professional advanced training program for military specialists in radiation safety for all branches of the Armed Forces of the Russian Federation, as well as to train officials responsible for organizing and ensuring radiationsafety in military units and organizations of the Ministry of Defense of the Russian Federation.The lecture addresses three educational questions:1. Accounting and control of radiation sources in the system of state accounting and control of radioactive substances and radioactive waste.2. General requirements for the operation of radiation sources.3. Operation of sealed radionuclide sources as part of the technical means of the RCB for intelligence and control.
讲座的目的是为参加俄罗斯联邦武装部队所有分支机构辐射安全军事专家额外专业高级培训课程的学生做好准备,并培训负责组织和确保俄罗斯联邦国防部军事单位和组织辐射安全的官员。讲座涉及三个教育问题:1。(一)国家放射性物质和放射性废物核算管理制度中放射源的核算和管理辐射源操作的一般要求。密封放射性核素源的操作,作为RCB情报和控制技术手段的一部分。
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引用次数: 0
Monkeypox: A Little-Studied Biological Threat to Russia 猴痘:对俄罗斯一种鲜有研究的生物威胁
Pub Date : 2022-06-27 DOI: 10.35825/2587-5728-2022-6-2-152-177
Monkeypox is a natural focal zoonosis of rodents and monkeys living in the Congo Valley (clade CB) and West Africa (clade WA). The special interest in monkeypox is due to its pandemic spread, which began in May 2022. The aim of this article is to consider the danger of monkeypox due to the lackof knowledge about its nature, as well as existing achievements in the treatment and prevention of this disease. The information was collected mainly from English-language sources available through the PubMed and Google Scholar databases. The study was conducted in the following areas: the epidemiology of monkeypox outbreaks until May 2022; taxonomy and origin of monkeypox virus (MPV); morphology and life cycle of poxviruses; ecology and epidemiology of MPV; the clinical pictureof monkeypox in humans with natural infection; monkeypox clinic in European homosexuals; clinical picture and pathomorphology of monkeypox in animals with artificial infection; immunoprophylaxisand therapy of monkeypox. It has been established that until May 2022 the appearance of MPV into non-endemic countries was limited to single cases of the disease. Because of that, the monkeypox pandemic that began in May 2022 looks atypical. The low-contagious MPV (WA) that caused it did not occur in Nigeria until 2017. Its spread was facilitated by a new mechanism of infection through organized homosexual contacts. Therefore, monkeypox should no longer be considered a rare diseasegeographically limited to the countries of West and Central Africa. It is also necessary to take into account the possibility of activating the natural reservoirs of other poxviruses, as well as the realization of their epidemic potential through immunodeficient human populations, which reach 20% of the total population in the developed countries. At present, there are no vaccines or drugs whose efficacy and safety have been confirmed in epidemic foci of MPV with immunodeficient populations. Serious efforts should be made to identify man-made outbreaks of monkeypox; to the identification of possible zoonotic hosts of MPV in Russia; factors that support MPV in ecosystems; host factors that determine the severity of the disease, as well as facilitating animal-to-human and human-to-human transmission
猴痘是生活在刚果河谷(CB支系)和西非(WA支系)的啮齿动物和猴子的一种自然局灶性人畜共患病。对猴痘的特别关注是由于其于2022年5月开始的大流行传播。本文的目的是考虑猴痘的危险,由于缺乏对其性质的认识,以及现有的成就,在治疗和预防这种疾病。这些信息主要收集自PubMed和Google Scholar数据库中可用的英语资源。该研究在以下领域进行:直到2022年5月猴痘暴发的流行病学;猴痘病毒(MPV)的分类和来源;痘病毒的形态和生命周期;流行性腮腺炎的生态学和流行病学;自然感染人猴痘的临床情况欧洲同性恋者猴痘门诊;人工感染猴痘动物的临床表现和病理形态猴痘的免疫预防和治疗。现已确定,直到2022年5月,MPV在非流行国家的出现仅限于该疾病的单一病例。正因为如此,始于2022年5月的猴痘大流行看起来是非典型的。导致该病的低传染性MPV (WA)直到2017年才在尼日利亚出现。通过有组织的同性恋接触,一种新的感染机制促进了它的传播。因此,猴痘不应再被视为一种在地理上仅限于西非和中非国家的罕见疾病。还必须考虑到激活其他痘病毒天然储存库的可能性,以及通过免疫缺陷人群实现其流行潜力的可能性,免疫缺陷人口占发达国家总人口的20%。目前,还没有疫苗或药物在免疫缺陷人群的MPV流行疫源地得到有效性和安全性的证实。应认真努力查明人为造成的猴痘疫情;在俄罗斯鉴定可能的MPV人畜共患宿主;支持生态系统中MPV的因素;宿主因素决定疾病的严重程度,并促进动物与人之间和人与人之间的传播
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引用次数: 0
Bactericidal Properties of Modular Protective Materials 模块化防护材料的杀菌性能
Pub Date : 2022-06-27 DOI: 10.35825/2587-5728-2022-6-2-123-136
Previously, the principle of constructing modular materials with specified properties was developed, according to which organometallic composites with nanoscale metal complexes introduced into them were applied to a unified fabric platform. The aim of the work was to study the properties of a unified fabric platform and to establish the possibility of giving protective bactericidal properties to fibrous materials (tissues). Such a platform has high stability and good bactericidal activity. It is shown in the article that the most significant indicators for tissue biocide were those reflecting the particle size of the dispersed phase, particle size distribution, the chemical composition of the dispersed phase, the qualitative and quantitative ratio of impurities in the dispersion medium, the concentration of particles of the dispersed phase in the dispersion medium, ζ-potential of particles of the dispersed phase; wettability of the fibers of the material by the main component of the dispersion medium (solvent), volatility of the main component of the dispersion medium (solvent). The bactericidal properties depended on the chosen method of fibrous material functionalization. Due to the principle of modular construction of materials with desired properties, it turned out to be possible to use organometallic composites with complexes of metal nanoparticles introduced into them. Studies of the biocidal activity of fibrous materials functionalized with metal nanoparticles in relation to different types of bacteria showed that it is possible to achieve characteristics comparable or even exceeding the known characteristics of antimicrobial drugs (benzetonium and benzalkonium chlorides) currently used in medical practice. As a unified fabric platform on which special modules are applied, it is proposed to use para–aramid protective fabric (Rusar fiber), as well as other types of fabrics - mixed aramid-viscose, aramid-cotton, aramid-polyacrylate, metaaramide (Nomex fiber).Approaches to giving materials (tissues) bactericidal protective properties are determined
在此之前,开发了构建具有特定性能的模块化材料的原理,根据该原理,将纳米级金属配合物引入有机金属复合材料中,应用于统一的织物平台。这项工作的目的是研究一个统一的织物平台的性能,并建立赋予纤维材料(组织)保护性杀菌性能的可能性。该平台稳定性高,杀菌活性好。研究结果表明,组织杀菌剂最重要的指标是反映分散相粒径、粒径分布、分散相化学组成、分散介质中杂质的定性和定量比、分散介质中分散相颗粒的浓度、分散相颗粒的ζ电位;材料纤维的润湿性受分散介质(溶剂)的主要成分影响,挥发性受分散介质(溶剂)的主要成分影响。其杀菌性能取决于纤维材料功能化方法的选择。由于具有所需性能的材料的模块化结构原理,使用金属纳米颗粒配合物的有机金属复合材料成为可能。对金属纳米颗粒功能化纤维材料对不同类型细菌的杀生物活性的研究表明,它有可能达到甚至超过目前在医疗实践中使用的抗菌药物(苯并溴铵和苯扎氯铵)的已知特性。作为应用特殊模块的统一织物平台,建议使用对芳纶防护织物(Rusar纤维),以及其他类型的织物-芳纶-粘胶,芳纶-棉,芳纶-聚丙烯酸酯,间芳纶(Nomex纤维)混合。确定了赋予材料(组织)杀菌保护性能的方法
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引用次数: 1
Federal Directorate for Safe Storage and Destruction of Chemical Weapons – 30th Anniversary 联邦安全储存和销毁化学武器局- 30周年纪念
Pub Date : 2022-06-27 DOI: 10.35825/2587-5728-2022-6-2-114-122
The Russian Federation has ratified the Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and on Their Destruction, and thereby reaffirmed its international obligations assumed in the field of chemical disarmament. To solve the problem of the destruction of chemical weapons, given its complexity and versatility, the Presidential Federal Target Program «Destruction of stockpiles of chemical weapons in the Russian Federation» was developed. This article is dedicated to the history of the formation of a unique structure – the Federal Office for the Safe Storage and Destruction of Chemical Weapons and the formation of a team of its specialists who directly performed the difficult task of destroying chemical weapons. September 27, 2017 at the facility for the destruction of chemical weapons in the village Kizner of the Udmurt Republic, in a special ceremony, the last chemical munition was destroyed. The Organization for the Prohibition of Chemical Weapons has recorded the fact of the complete destruction of chemical weapons in the Russian Federation with the relevant certificates. The program for the destruction of chemical weapons was completed 3 years ahead of schedule, with savings of 9.6 billion rubles. The main results of the completed process of destruction of chemical weapons are that no human life has been lost and no damage has been done to the environment. Currently, the Federal Directorate is implementing measures within the framework of the departmental project «Liquidation of the consequences of the activities of storage facilities and facilities for the destruction of chemical weapons in the Russian Federation» of the state program of the Russian Federation «Development of industry and increasing its competitiveness»
俄罗斯联邦批准了《关于禁止发展、生产、储存和使用化学武器和销毁此种武器的公约》,从而重申了它在化学裁军领域所承担的国际义务。为了解决化学武器销毁问题,鉴于其复杂性和多功能性,制定了“销毁俄罗斯联邦化学武器库存”总统联邦目标计划。本文致力于介绍一个独特结构的形成历史- -安全储存和销毁化学武器联邦办公室及其专家小组的形成,他们直接执行销毁化学武器的艰巨任务。2017年9月27日,在乌德穆尔特共和国基兹纳村销毁化学武器设施举行的特别仪式上,最后一枚化学弹药被销毁。禁止化学武器组织记录了俄罗斯联邦境内化学武器已被彻底销毁的事实,并出具了有关证明。销毁化学武器计划提前3年完成,节省96亿卢布。完成化学武器销毁进程的主要结果是没有人丧生,没有对环境造成破坏。目前,联邦总局正在俄罗斯联邦国家计划“发展工业并提高其竞争力”的部门项目“消除俄罗斯联邦化学武器储存设施和销毁设施活动的后果”的框架内实施措施
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引用次数: 0
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Journal of NBC Protection Corps
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