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What's the difference between human-written manuscripts versus ChatGPT-generated manuscripts involving “human touch”?
IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-05 DOI: 10.1111/jog.16226
Shigeki Matsubara, Daisuke Matsubara

Aim

To determine whether ChatGPT generates a manuscript with a “human touch” with appropriate inputs, and if yes, what's the difference between human writing versus ChatGPT writing. This is because the presence or absence of human touch may characterize human writing.

Methods

A descriptive study. The first author wrote a Disagreement Letter (Letter 1). Then, disagreement points and “human touch” were provided as input into ChatGPT-4 and tasked with generating a Letter (Letter 2). The authors, seven experienced researchers, and ChatGPT evaluated the readability of Letters 1 and 2.

Results

The authors, researchers, and ChatGPT, all reached the same conclusions: the human-written Letter 1 and the ChatGPT-generated Letter 2 had similar readability and similarly involved human touch. Some researchers and ChatGPT recognized slight differences in formal or informal and personal or nonpersonal tones between them, which they considered may not affect paper acceptance.

Conclusions

Human touch is not humans' exclusive possession. The distinction between the human writing versus ChatGPT writing is considered to be present not in the output (manuscript) but in the process of writing, that is, the presence or absence of a joy of writing. Artificial intelligence should aid in enhancing, or at the very least, not impede the human joy. This discussion deserves ongoing exploration.

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引用次数: 0
Evaluation of fetal aortic isthmus diameter and flow in pregnant women with intrahepatic cholestasis of pregnancy; may it be a marker of poor perinatal outcomes?
IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-31 DOI: 10.1111/jog.16222
Ezgi Başaran, Fatma Doğa Öcal, Atakan Tanaçan, Zahid Ağaoğlu, Göksun Ipek, Betül Akgün Aktaş, Dilek Şahin

Aim

To evaluate the fetal aortic isthmus (AoI) diameter and flow in pregnant women diagnosed with intrahepatic cholestasis of pregnancy (ICP).

Methods

In this prospective case–control study, fetal AoI diameter and Doppler measurements were performed in the ICP group (n: 30) and the control group (n: 42). Clinical characteristics, fetal AoI diameter and Doppler measurements, serum bile acid levels, liver enzyme levels, and obstetric and perinatal outcomes were compared between the groups.

Results

The AoI diameter was 4.8 ± 0.95 mm in the ICP group and 4.2 ± 0.62 mm in the control group, indicating a statistically significant difference (p = 0.003). The AoI Doppler flow parameters did not significantly differ between the groups (p > 0.05). When evaluated in subgroups according to disease severity, the AoI diameter and Doppler measurements did not significantly differ between the mild and severe ICP cases (p > 0.05). The AoI diameter was significantly larger in those requiring admission to the neonatal intensive care unit (NICU) (p = 0.005). This diameter was also larger in patients with fetal distress, albeit with no statistically significant difference (p = 0.65).

Conclusions

ICP is a pathology with known adverse fetal cardiac effects, but there is no effective method to predict adverse perinatal outcomes. The enlarged AoI diameter in the fetuses of mothers with ICP and the association of this enlargement with NICU requirements are important findings of this study. Further research with a larger number of patients is necessary to evaluate the clinical utility of fetal AoI diameter and Doppler parameters in ICP.

{"title":"Evaluation of fetal aortic isthmus diameter and flow in pregnant women with intrahepatic cholestasis of pregnancy; may it be a marker of poor perinatal outcomes?","authors":"Ezgi Başaran,&nbsp;Fatma Doğa Öcal,&nbsp;Atakan Tanaçan,&nbsp;Zahid Ağaoğlu,&nbsp;Göksun Ipek,&nbsp;Betül Akgün Aktaş,&nbsp;Dilek Şahin","doi":"10.1111/jog.16222","DOIUrl":"10.1111/jog.16222","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To evaluate the fetal aortic isthmus (AoI) diameter and flow in pregnant women diagnosed with intrahepatic cholestasis of pregnancy (ICP).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this prospective case–control study, fetal AoI diameter and Doppler measurements were performed in the ICP group (<i>n</i>: 30) and the control group (<i>n</i>: 42). Clinical characteristics, fetal AoI diameter and Doppler measurements, serum bile acid levels, liver enzyme levels, and obstetric and perinatal outcomes were compared between the groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The AoI diameter was 4.8 ± 0.95 mm in the ICP group and 4.2 ± 0.62 mm in the control group, indicating a statistically significant difference (<i>p</i> = 0.003). The AoI Doppler flow parameters did not significantly differ between the groups (<i>p</i> &gt; 0.05). When evaluated in subgroups according to disease severity, the AoI diameter and Doppler measurements did not significantly differ between the mild and severe ICP cases (<i>p</i> &gt; 0.05). The AoI diameter was significantly larger in those requiring admission to the neonatal intensive care unit (NICU) (<i>p</i> = 0.005). This diameter was also larger in patients with fetal distress, albeit with no statistically significant difference (<i>p</i> = 0.65).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>ICP is a pathology with known adverse fetal cardiac effects, but there is no effective method to predict adverse perinatal outcomes. The enlarged AoI diameter in the fetuses of mothers with ICP and the association of this enlargement with NICU requirements are important findings of this study. Further research with a larger number of patients is necessary to evaluate the clinical utility of fetal AoI diameter and Doppler parameters in ICP.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal cardiovascular dynamics in twin pregnancies complicated by twin-to-twin transfusion syndrome
IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-31 DOI: 10.1111/jog.16224
Hikari Kotaki, Mayu Tachihara, Mio Kamiya, Makiko Shimabukuro, Junya Sakuma, Mayumi Takano, Sumito Nagasaki, Hiroshi Ohara, Masahiko Nakata

Aim

Twin pregnancies affect maternal circulation by increasing the circulating blood volume and enlarging the uterus due to excess amniotic fluid. Nevertheless, how twin-to-twin transfusion syndrome (TTTS) affects maternal circulation remains unclear. Our aim was to examine maternal circulation changes at TTTS onset.

Methods

This cohort study was conducted at the Toho University Omori Medical Center from October 2022 to September 2023. Patients were divided into three groups, singleton pregnancy (singleton), uncomplicated monochorionic diamniotic (MD) twin pregnancy (nMD), and TTTS groups. We prospectively collected echocardiographic data to evaluate the left ventricular function, left ventricular contractility, diastolic performance, and inferior vena cava diameter.

Results

Thirty-one, 17, and 18 patients were assigned to the singleton, nMD, and TTTS groups, respectively. The left ventricular end-systolic volume (ESV) was significantly lower in the TTTS group than in the nMD group [ESV: 23.9 ± 9.2 mL vs. 13.3 ± 8.4 mL]. The left ventricular end-diastolic volume (EDV) was no significant difference, but a decreasing trend in the TTTS group than in the nMD group. The left ventricular ejection fraction was significantly lower in the nMD group than in the TTTS group [72.2 ± 6.4% vs. 80.1 ± 5.9%]. The heart rate was significantly higher in the TTTS group than in the other two groups. Cardiac output was similar among the groups.

Conclusions

MD twin pregnancy with TTTS may decrease circulating blood volumes. Maternal cardiac function may be adapted to compensate for cardiac output in patients with TTTS.

{"title":"Maternal cardiovascular dynamics in twin pregnancies complicated by twin-to-twin transfusion syndrome","authors":"Hikari Kotaki,&nbsp;Mayu Tachihara,&nbsp;Mio Kamiya,&nbsp;Makiko Shimabukuro,&nbsp;Junya Sakuma,&nbsp;Mayumi Takano,&nbsp;Sumito Nagasaki,&nbsp;Hiroshi Ohara,&nbsp;Masahiko Nakata","doi":"10.1111/jog.16224","DOIUrl":"10.1111/jog.16224","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Twin pregnancies affect maternal circulation by increasing the circulating blood volume and enlarging the uterus due to excess amniotic fluid. Nevertheless, how twin-to-twin transfusion syndrome (TTTS) affects maternal circulation remains unclear. Our aim was to examine maternal circulation changes at TTTS onset.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cohort study was conducted at the Toho University Omori Medical Center from October 2022 to September 2023. Patients were divided into three groups, singleton pregnancy (singleton), uncomplicated monochorionic diamniotic (MD) twin pregnancy (nMD), and TTTS groups. We prospectively collected echocardiographic data to evaluate the left ventricular function, left ventricular contractility, diastolic performance, and inferior vena cava diameter.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Thirty-one, 17, and 18 patients were assigned to the singleton, nMD, and TTTS groups, respectively. The left ventricular end-systolic volume (ESV) was significantly lower in the TTTS group than in the nMD group [ESV: 23.9 ± 9.2 mL vs. 13.3 ± 8.4 mL]. The left ventricular end-diastolic volume (EDV) was no significant difference, but a decreasing trend in the TTTS group than in the nMD group. The left ventricular ejection fraction was significantly lower in the nMD group than in the TTTS group [72.2 ± 6.4% vs. 80.1 ± 5.9%]. The heart rate was significantly higher in the TTTS group than in the other two groups. Cardiac output was similar among the groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>MD twin pregnancy with TTTS may decrease circulating blood volumes. Maternal cardiac function may be adapted to compensate for cardiac output in patients with TTTS.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fresh frozen plasma, fibrinogen concentrate, and antithrombin concentrate administration for obstetrical disseminated intravascular coagulation by the Japanese previous and new criteria
IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-29 DOI: 10.1111/jog.16220
Mamoru Morikawa, Shigetaka Matsunaga, Shintaro Makino, Yoshiharu Takeda, Hironobu Hyodo, Masafumi Nii, Mariko Serizawa, Eriko Eto, Jun Takeda, Tomoko Adachi, Takao Kobayashi, Atsuo Itakura

Aim

The purpose of this study is to clarify the frequencies of fresh frozen plasma (FFP) ± fibrinogen concentrate administration (fibrinogen concentrate [FC] therapy) and antithrombin (AT) concentrate administration (AT therapy) for the women with obstetrical disseminated intravascular coagulation (DIC).

Methods

Two retrospective multicenter case–control studies as Study-1 (January–December 2018) and Study-2 (July 2022–June 2023) were conducted. Study-1 was the historical control of Study-2. All participants experienced a blood loss of ≥1000 mL during vaginal delivery or ≥2000 mL during cesarean section. All participants were subsequently assigned to the DIC group or non-DIC group.

Results

Study-1 comprised 175 women (obstetrical DIC, 27; control, 148; by the previous criteria) and Study-2 comprised 175 women (obstetrical DIC, 9; control, 166; by the new criteria). The frequencies of FFP (±FC therapy) or FC therapy in DIC group were significantly higher than non-DIC group in Study-1 (88.9% vs. 25.0%, 44.4% vs. 4.0%) and Study-2 (100% vs. 24.7%, 77.8% vs. 5.4%); however, the frequencies of AT therapy were similar. Furthermore, in the DIC group, all women with fibrinogen <150 mg/dL received FFP ± FC therapy in Study-1 (n = 19) and Study-2 (n = 8); however, those with AT activity <70% received AT therapy (16.7% [4/24] and 12.5% [1/8], respectively).

Conclusion

We revealed an association between the high frequency of FFP ± FC therapy and lower fibrinogen levels, but a low frequency of AT therapy regardless of AT activity, in obstetrical DIC regardless of diagnosis criteria.

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引用次数: 0
Association between sleep problems during pregnancy and postpartum depressive symptoms as well as condition of newborn at delivery
IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-26 DOI: 10.1111/jog.16219
Yoko Komada, Sho-Ichi Kawakami, Satoko Furuie, Rena Mori, Azusa Ikegami

Background

Pregnancy-related anatomic, physiologic, and hormonal factors can occur at different stages of pregnancy and affect sleep disturbances. The relationship between sleep problems during pregnancy and postpartum depressive symptoms as well as neonatal condition at delivery have not been well described. This study hypothesized that sleep problems are associated with postpartum depressive symptoms and adverse neonatal outcomes at delivery.

Methods

This study conducted a prospective study for perinatal women (n = 683, 30.54 ± 5.11 years old) to evaluate sleep problems during pregnancy using the Pittsburgh sleep quality index (PSQI) and Berlin questionnaire, postpartum depressive symptoms using Edinburgh postnatal depression scale (EPDS), and clinical signs of neonatal condition at delivery using the Apgar score.

Results

PSQI total score during pregnancy were significantly higher in those with postpartum depressive symptoms than those without 1 month after delivery. PSQI score in the third trimester was significantly associated with postpartum depressive symptoms even after adjustment for relevant confounding factors and self-reported lifetime depression (odds ratio = 1.19, 95% confidence interval = 1.03–1.36, p = 0.015). The Apgar score at 5 min after birth was significantly lower in those with obstructive sleep apnea (OSA) than those without OSA in the second and third trimesters, although mean scores were within the normal range.

Conclusion

This study revealed that sleep problems during pregnancy influence postpartum depression 1 month after delivery. OSA during pregnancy may lead to risks of delivery. Attention should be paid to sleep health during pregnancy to ensure the mental health of mothers and a safe delivery.

{"title":"Association between sleep problems during pregnancy and postpartum depressive symptoms as well as condition of newborn at delivery","authors":"Yoko Komada,&nbsp;Sho-Ichi Kawakami,&nbsp;Satoko Furuie,&nbsp;Rena Mori,&nbsp;Azusa Ikegami","doi":"10.1111/jog.16219","DOIUrl":"10.1111/jog.16219","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Pregnancy-related anatomic, physiologic, and hormonal factors can occur at different stages of pregnancy and affect sleep disturbances. The relationship between sleep problems during pregnancy and postpartum depressive symptoms as well as neonatal condition at delivery have not been well described. This study hypothesized that sleep problems are associated with postpartum depressive symptoms and adverse neonatal outcomes at delivery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study conducted a prospective study for perinatal women (<i>n</i> = 683, 30.54 ± 5.11 years old) to evaluate sleep problems during pregnancy using the Pittsburgh sleep quality index (PSQI) and Berlin questionnaire, postpartum depressive symptoms using Edinburgh postnatal depression scale (EPDS), and clinical signs of neonatal condition at delivery using the Apgar score.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>PSQI total score during pregnancy were significantly higher in those with postpartum depressive symptoms than those without 1 month after delivery. PSQI score in the third trimester was significantly associated with postpartum depressive symptoms even after adjustment for relevant confounding factors and self-reported lifetime depression (odds ratio = 1.19, 95% confidence interval = 1.03–1.36, <i>p</i> = 0.015). The Apgar score at 5 min after birth was significantly lower in those with obstructive sleep apnea (OSA) than those without OSA in the second and third trimesters, although mean scores were within the normal range.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study revealed that sleep problems during pregnancy influence postpartum depression 1 month after delivery. OSA during pregnancy may lead to risks of delivery. Attention should be paid to sleep health during pregnancy to ensure the mental health of mothers and a safe delivery.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of textbook oncologic outcome after neoadjuvant chemotherapy and interval debulking surgery for advanced ovarian cancer
IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-23 DOI: 10.1111/jog.16218
Jiayin Yu, Yiyang Wang, Liqun Liu, Yaolong Xiao, Gang Yu

Aim

To examine the prognostic impact of textbook oncologic outcome (TOO) in patients with advanced ovarian cancer undergoing primary chemotherapy, along with identifying the risk factors for TOO failure.

Methods

Patients who underwent neoadjuvant chemotherapy followed by interval debulking surgery for advanced ovarian cancer at a tertiary center between 2014 and 2019 were retrospectively reviewed. TOO was defined as complete cytoreduction, no severe complications, no prolonged hospital stay, no readmission, no delayed initiation of adjuvant chemotherapy, and no 90-day mortality. The associations between TOO and clinical characteristics (survival) were examined using logistic and Cox regression analyses.

Results

Among 165 patients, 65 (39.4%) achieved TOO. The most common reason for TOO failure was incomplete cytoreduction (n = 46, 27.9%). Older age (p = 0.049) and visceral obesity (p = 0.030) were independently associated with TOO failure. Patients who achieved TOO had significantly prolonged overall survival (OS; median: 52 vs. 31 months, p = 0.010) and progression-free survival (PFS; median: not reached vs. 19 months, p = 0.006) compared to those who did not achieve TOO. Multivariate analysis revealed that TOO achievement was an independent protective factor for OS (hazard ratio [HR] 0.591, 95% confidence interval [CI] 0.387–0.905, p = 0.015) and PFS (HR 0.626, 95% CI 0.410–0.956, p = 0.030).

Conclusions

TOO is an effective predictor of favorable outcomes in patients with advanced ovarian cancer undergoing interval debulking surgery. Factors such as older age and visceral obesity may hinder the achievement of TOO.

{"title":"Assessment of textbook oncologic outcome after neoadjuvant chemotherapy and interval debulking surgery for advanced ovarian cancer","authors":"Jiayin Yu,&nbsp;Yiyang Wang,&nbsp;Liqun Liu,&nbsp;Yaolong Xiao,&nbsp;Gang Yu","doi":"10.1111/jog.16218","DOIUrl":"10.1111/jog.16218","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To examine the prognostic impact of textbook oncologic outcome (TOO) in patients with advanced ovarian cancer undergoing primary chemotherapy, along with identifying the risk factors for TOO failure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients who underwent neoadjuvant chemotherapy followed by interval debulking surgery for advanced ovarian cancer at a tertiary center between 2014 and 2019 were retrospectively reviewed. TOO was defined as complete cytoreduction, no severe complications, no prolonged hospital stay, no readmission, no delayed initiation of adjuvant chemotherapy, and no 90-day mortality. The associations between TOO and clinical characteristics (survival) were examined using logistic and Cox regression analyses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among 165 patients, 65 (39.4%) achieved TOO. The most common reason for TOO failure was incomplete cytoreduction (<i>n</i> = 46, 27.9%). Older age (<i>p</i> = 0.049) and visceral obesity (<i>p</i> = 0.030) were independently associated with TOO failure. Patients who achieved TOO had significantly prolonged overall survival (OS; median: 52 vs. 31 months, <i>p</i> = 0.010) and progression-free survival (PFS; median: not reached vs. 19 months, <i>p</i> = 0.006) compared to those who did not achieve TOO. Multivariate analysis revealed that TOO achievement was an independent protective factor for OS (hazard ratio [HR] 0.591, 95% confidence interval [CI] 0.387–0.905, <i>p</i> = 0.015) and PFS (HR 0.626, 95% CI 0.410–0.956, <i>p</i> = 0.030).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>TOO is an effective predictor of favorable outcomes in patients with advanced ovarian cancer undergoing interval debulking surgery. Factors such as older age and visceral obesity may hinder the achievement of TOO.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143033375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Women's health care committee, Japan Society of Obstetrics and Gynecology: Annual report—2024 日本妇产科学会妇女保健委员会:年度报告-2024。
IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-22 DOI: 10.1111/jog.16192
Tsuyoshi Higuchi, Takeshi Iwasa

The Women's Health Care Committee was established in 2010 to improve the health of women. In the current academic year, this committee established seven subcommittees aimed at understanding diseases related to various age groups of women, including adolescence, sexual maturity, and menopause, and promoting research to improve the quality of life. Additionally, socially significant research has focused on infections, particularly resistant bacteria. The activities of each subcommittee are described. This report is based on the Japanese version of the annual report (Acta Obst Gynaec Jpn 2024;76(6):682–87).

妇女保健委员会于2010年成立,旨在改善妇女的健康状况。在本学年,该委员会成立了七个小组委员会,旨在了解与不同年龄组妇女有关的疾病,包括青春期、性成熟期和更年期,并促进研究以提高生活质量。此外,具有社会意义的研究集中在感染上,特别是耐药细菌。描述了每个小组委员会的活动。本报告基于年度报告的日文版本(Acta Obst Gynaec Jpn 2024;76(6):682-87)。
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引用次数: 0
Birth and pregnancy numbers decreased during the COVID-19 pandemic in Japan: A time series analysis with the ARIMA model 在日本COVID-19大流行期间,出生和怀孕人数减少:使用ARIMA模型的时间序列分析。
IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-21 DOI: 10.1111/jog.16202
Keiko Yamamoto, Koji Uchiyama, Yoshiko Abe, Nobuko Takaoka, Yasuo Haruyama, Gen Kobashi

Aim

The long-term effects of the COVID-19 pandemic on birth and pregnancy trends in Japan remain unclear. Although major sporting events are usually followed by an increase in births 9 months later, Japan's fifth wave of COVID-19 occurred during the Olympics held in Japan during the summer of 2021. In this study, we analyzed how the number of births and pregnancies changed during the COVID-19 pandemic and large-scale events in Japan.

Methods

We utilized monthly vital statistical data from birth certificates spanning the years 2010 to 2022. Our analysis followed the identification, estimation, and forecasting stages of autoregressive integrated moving average (ARIMA) modeling. We found the ARIMA (1, 12, 12) model to be adequate for forecasting the monthly number of births.

Results

Comparing actual birth data from 2020 to 2022 with our forecast, we observed a significant decrease in births across all of Japan, urban residential areas, and 13 prefectures—primarily metropolitan regions—in January 2021 and May 2022. We also observed a decrease in pregnancy notifications in May 2020, May 2021, and October 2021. The decrease in births in May 2022 in Japan aligns with the decrease in pregnancy notifications 8 months earlier in October 2021.

Conclusions

Although major sporting events are expected to lead to an increase in the number of births approximately 9 months later, the number of births decreased in May 2022 during the fifth wave of the COVID-19 pandemic in Japan. These findings suggest that the number of pregnancies and births should be monitored in future pandemics with particular attention to fertility trends.

目的:COVID-19大流行对日本出生和怀孕趋势的长期影响尚不清楚。虽然重大体育赛事之后通常会在9个月后出现出生率增加,但日本的第五波新冠肺炎疫情发生在2021年夏季在日本举行的奥运会期间。在这项研究中,我们分析了日本在COVID-19大流行和大规模事件期间出生和怀孕数量的变化。方法:利用2010 ~ 2022年出生证明的月度生命统计数据。我们的分析遵循自回归综合移动平均(ARIMA)模型的识别、估计和预测阶段。我们发现ARIMA(1,12,12)模型足以预测月出生数。结果:将2020年至2022年的实际出生数据与我们的预测进行比较,我们观察到2021年1月至2022年5月,日本所有地区、城市住宅区和13个县(主要是大都市地区)的出生人数显著减少。我们还观察到,2020年5月、2021年5月和2021年10月的妊娠通知有所减少。日本2022年5月的出生率下降与8个月前2021年10月的怀孕通知减少相一致。结论:虽然预计重大体育赛事将在大约9个月后导致出生人数增加,但在2022年5月日本第五波COVID-19大流行期间,出生人数有所减少。这些发现表明,在今后的大流行病中,应监测怀孕和分娩人数,并特别注意生育趋势。
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引用次数: 0
Clinical outcomes after 2-year follow-up of transvaginal radiofrequency ablation of symptomatic uterine fibroids 经阴道射频消融治疗症状性子宫肌瘤2年随访的临床结果。
IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-21 DOI: 10.1111/jog.16216
Ángel Santalla-Hernández, Mariña Naveiro-Fuentes, María Setefilla López-Criado, Roi Naveiro-Flores, Jorge Fernández-Parra

Aim

The aim of this study was to evaluate the efficacy after 2 years follow-up of transvaginal radiofrequency ablation (TVRA) to treat myomas, and to identify factors predictive of the response to the treatment.

Methods

This is a prospective cohort study of a 2-year follow-up of 65 patients who underwent TVRA for the treatment uterine fibroids at Virgen de las Nieves University Hospital in Granada, Spain. Ultrasound mean fibroid volume, symptom severity scale, total bleeding days, complications, pregnancy outcomes were recorded.

Results

Statistically significant improvements in symptoms and bleeding were observed at 6, 12, and 24 months after the procedure. The mean myoma volume (cc) was significantly lower (p < 0.05) at 12 and 24 months, with a mean reduction in myoma volume of more than 80% and 60%, respectively. After a 24-month follow-up, 5 patients (7.7%) required additional surgical treatment to control symptoms. Patient age (>40 years), initial myoma size, and the timing of radiofrequency were identified as factors related to outcomes in the bivariate analysis.

Conclusions

Transvaginal radiofrequency ablation is an effective and safe technique for the treatment of myomas after 2 years of follow-up, which improves the symptoms of the patients and decreases the final volume of the myoma.

目的:本研究的目的是评估经阴道射频消融(TVRA)治疗肌瘤2年随访后的疗效,并确定预测治疗反应的因素。方法:这是一项前瞻性队列研究,对65名在西班牙格拉纳达的维珍·德·拉斯·尼夫斯大学医院接受TVRA治疗子宫肌瘤的患者进行了为期2年的随访。记录超声平均肌瘤体积、症状严重程度、总出血天数、并发症、妊娠结局。结果:在术后6、12和24个月观察到症状和出血的统计学显著改善。在双变量分析中,平均肌瘤体积(cc)显著降低(p 40年),初始肌瘤大小和射频时间被确定为与结果相关的因素。结论:经阴道射频消融治疗肌瘤经过2年的随访,是一种有效、安全的治疗肌瘤的技术,可以改善患者的症状,减少肌瘤的最终体积。
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引用次数: 0
Endometrial cancer with para-aortic lymph node metastasis following medroxyprogesterone acetate therapy: A case report 醋酸甲孕酮治疗后子宫内膜癌伴主动脉旁淋巴结转移1例。
IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-21 DOI: 10.1111/jog.16217
Miku Nakamura, Yoshifumi Takahashi, Takahiro Koyanagi, Yuji Takei, Hiroyuki Fujiwara

Medroxyprogesterone acetate (MPA) is a promising fertility-sparing treatment for early stage endometrial cancer; however, it has a high recurrence rate and is inferior to surgery. Although the site of recurrence is mostly the endometrium, we here report a case of metastatic recurrence to the para-aortic lymph node with endometrial recurrence despite a careful follow-up. A 31-year-old woman was diagnosed with grade 1 endometrioid carcinoma, stage IA without myometrial invasion. She requested fertility-sparing treatment and underwent a 48-week MPA therapy with complete remission. Follow-up continued with ultrasonography and endometrial biopsy every 3 and 6 months, respectively; however, at 10 months following MPA therapy, cancer recurrence was detected in the endometrium and para-aortic lymph node, requiring hysterectomy, bilateral adnexectomy, and lymph node dissection, followed by paclitaxel/carboplatin chemotherapy. This case report highlights that lymph node recurrence can develop despite careful follow-up following complete remission with MPA therapy for stage IA endometrial cancer.

醋酸甲羟孕酮(MPA)是早期子宫内膜癌的一种有希望的生育保留治疗方法;然而,它有很高的复发率,不如手术。虽然复发部位主要是子宫内膜,但我们在此报告一例转移性复发至主动脉旁淋巴结并子宫内膜复发的病例,尽管我们进行了仔细的随访。一位31岁的女性被诊断为1级子宫内膜样癌,IA期无子宫肌瘤浸润。她要求保留生育能力的治疗,并接受了48周的MPA治疗,完全缓解。继续随访,分别每3个月和6个月进行超声检查和子宫内膜活检;然而,在MPA治疗10个月后,在子宫内膜和主动脉旁淋巴结发现癌症复发,需要子宫切除术、双侧附件切除术和淋巴结清扫,然后进行紫杉醇/卡铂化疗。本病例报告强调,IA期子宫内膜癌经MPA治疗完全缓解后,尽管仔细随访,淋巴结复发仍可能发生。
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引用次数: 0
期刊
Journal of Obstetrics and Gynaecology Research
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