Journal of Obstetrics and Gynaecology Research最新文献_第6页

Efficacy of Postoperative Para-Aortic and Pelvic Lymphadenectomies for Intermediate- to High-Risk Endometrial Cancer 腹主动脉旁淋巴结和盆腔淋巴结切除术治疗中至高危子宫内膜癌的疗效观察。

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research

Pub Date : 2026-02-15 DOI: 10.1111/jog.70194

Asumi Okumura, Kenta Yoshida, Saki Kotaka, Kota Okamoto, Tsuyoshi Matsumoto, Michiko Kubo-Kaneda, Eiji Kondo

Purpose

A two-stage surgery for endometrial cancer is associated with a high physical and psychological burden on the patient and possibly increases the risk of subsequent abdominal surgeries. In this study, we aimed to characterize the oncological features of endometrial cancer patients with lymph node-positive and lymph node-recurrent disease who underwent two-stage lymphadenectomy after initial hysterectomy without pelvic and para-aortic lymphadenectomy and were at intermediate or high risk for postoperative recurrence.

Methods

This single-center retrospective study evaluated a total of 37 patients with endometrial cancer who underwent postoperative para-aortic lymphadenectomy between April 2020 and March 2023.

Results

The median follow-up duration was 42 months. The 3-year survival rate was 90%, and the 3-year recurrence-free survival rate was 80%. Lymph node metastasis occurred in 13.5% of the patients, of whom 2.7% had skip metastases in the para-aortic lymph nodes only. Histologically, most patients (80%) had endometrioid carcinoma grade 1. Overall recurrence was observed in 16.2%. The median recurrence-free survival time was 20.5 months. Poorly differentiated or non-endometrioid histology was found in 66.6% of the patients. All patients with low-grade endometrioid carcinoma with lymph node metastasis or recurrence had p53 mutations.

Conclusion

No patients with lymph node metastasis relapsed during the follow-up period. Two-stage lymphadenectomy may have contributed to the favorable outcomes. However, it is difficult to perform molecular pathological evaluation in all cases preoperatively. Therefore, it is acceptable to perform a hysterectomy and undergo a two-stage lymphadenectomy in minimally invasive surgery according to risk classification.

目的：子宫内膜癌的两期手术会给患者带来很高的生理和心理负担，并可能增加后续腹部手术的风险。在本研究中，我们旨在描述淋巴结阳性和淋巴结复发的子宫内膜癌患者的肿瘤特征，这些患者在最初的子宫切除术后进行了两期淋巴结切除术，不包括盆腔和腹主动脉旁淋巴结切除术，术后复发的风险为中或高风险。方法：本单中心回顾性研究评估了2020年4月至2023年3月期间接受术后主动脉旁淋巴结切除术的37例子宫内膜癌患者。结果：中位随访时间为42个月。3年生存率90%，3年无复发生存率80%。13.5%的患者发生淋巴结转移，其中2.7%仅在主动脉旁淋巴结发生跳跃性转移。组织学上，大多数患者（80%）为1级子宫内膜样癌。总复发率为16.2%。中位无复发生存期为20.5个月。66.6%的患者存在低分化或非子宫内膜样组织。低级别子宫内膜样癌伴淋巴结转移或复发的患者均有p53突变。结论：随访期间无一例淋巴结转移复发。两期淋巴结切除术可能有助于良好的结果。然而，术前很难对所有病例进行分子病理评估。因此，在微创手术中，根据风险分级，行子宫切除术和两期淋巴结切除术是可以接受的。

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引用次数: 0

Gestational Age-Dependent Effects of Antenatal Magnesium Sulfate on Fetal S100B Levels: An Observational Study Using Cord Serum 胎龄依赖性硫酸镁对胎儿S100B水平的影响：脐带血清观察性研究

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research

Pub Date : 2026-02-15 DOI: 10.1111/jog.70208

Takuma Shimaya, Kazuya Fuma, Sho Tano, Seiko Matsuo, Takafumi Ushida, Kenji Imai, Hiroaki Kajiyama, Tomomi Kotani

Aim

Magnesium sulfate (MgSO₄) is widely used for fetal neuroprotection in preterm births before 32 weeks of gestation, yet it remains unclear whether its effect depends on gestational age. S100 calcium-binding protein B (S100B), a protein secreted by astrocytes, is recognized as a biomarker of neural distress. This study aimed to investigate the relationship between antenatal MgSO₄ administration and umbilical cord serum S100B levels, with a focus on gestational age.

Methods

This retrospective study included women who delivered between 22⁺⁰ and 33⁺⁶ weeks of gestation at a tertiary center. Patients with hypertensive disorders of pregnancy, category 1 cesarean sections, multiple pregnancies, major congenital anomalies, or insufficient MgSO₄ administration were excluded. Cord blood samples were analyzed for S100B levels using ELISA. Multiple linear regression and restricted cubic spline modeling were performed to assess the association between MgSO₄ and S100B levels across different gestational ages.

Results

Among 69 eligible patients, MgSO₄ administration was significantly associated with higher cord serum S100B levels who delivered at ≥ 30 weeks of gestation (adjusted estimate 0.39, 95% confidence interval 0.17–0.62), but not in those who delivered at < 30 weeks (−0.12, −0.43 to 0.19) in multiple linear regression adjusted for birth weight and antenatal corticosteroids. This association remained consistent across multiple sensitivity analyses. S100B levels exhibited a gestational age-dependent increase in response to MgSO₄, peaking at approximately 32 weeks in restricted cubic spline modeling.

Conclusions

Antenatal MgSO₄ administration beyond 30 weeks of gestation at delivery is associated with increased fetal S100B levels, suggesting a potential gestational age-specific response.

目的：硫酸镁（MgSO4）广泛用于妊娠32周前早产儿的胎儿神经保护，但其作用是否与胎龄有关尚不清楚。S100钙结合蛋白B （S100B）是星形胶质细胞分泌的一种蛋白，被认为是神经窘迫的生物标志物。本研究旨在探讨产前MgSO4给药与脐带血清S100B水平的关系，重点关注胎龄。方法：本回顾性研究包括在三级中心分娩的妊娠22+0至33+6周的妇女。排除妊娠期高血压疾病、1类剖宫产、多胎妊娠、重大先天性异常或MgSO4给药不足的患者。采用ELISA法分析脐带血S100B水平。采用多元线性回归和限制三次样条模型来评估不同胎龄MgSO4和S100B水平之间的关系。结果：在69例符合条件的患者中，MgSO4给药与妊娠≥30周分娩的脐带血清S100B水平升高显著相关（调整后的估计为0.39,95%可信区间为0.17-0.62），但与妊娠4周分娩的患者无关，在限制性三次样条模型中，其峰值约为32周。结论：在分娩时给予妊娠30周以上的MgSO4与胎儿S100B水平升高有关，表明可能存在孕龄特异性反应。

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引用次数: 0

Interval Vaginal Delivery of Term Twins From Bilateral Horns of a Uterus Didelphys: Insight Into Labor Initiation and Progression 间隔阴道分娩足月双胞胎从双侧子宫角：洞察分娩的开始和进展。

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research

Pub Date : 2026-02-13 DOI: 10.1111/jog.70206

Daiki Hiratsuka, Takayuki Iriyama, Seisuke Sayama, Keiichi Kumasawa, Miyuki Harada, Yasushi Hirota

Uterus didelphys, characterized by two separate uterine cavities and cervices, is associated with increased obstetric complications. Twin pregnancy with one fetus in each horn is exceptionally rare, often managed by cesarean or resulting in preterm birth. We report the first known case of term vaginal deliveries from both horns, occurring 6 days apart. A 28-year-old woman with uterus didelphys spontaneously conceived twins, with one fetus in each horn. At 37 + 4 weeks of gestation, labor began spontaneously in the left uterus. The cardiotocogram initially showed asynchronous contractions between the horns during the latent phase, becoming synchronous in the active phase. The first twin was delivered via forceps due to non-reassuring fetal status. The right uterus showed weak contractions but did not progress to labor. Six days later, labor was induced, and the second twin was also delivered via forceps. This case offers rare clinical insight into labor initiation and inter-horn coordination.

子宫双裂的特点是两个独立的子宫腔和子宫颈，与产科并发症增加有关。双胎妊娠，每个角有一个胎儿是非常罕见的，通常通过剖宫产或导致早产。我们报告了第一例已知的阴道分娩从两个角，相隔6天发生。一名28岁的女性子宫双裂生了一对自然受孕的双胞胎，每个角上都有一个胎儿。妊娠37 + 4周时，左侧子宫开始自然分娩。在潜伏期，心电图显示角间的不同步收缩，在活动期变为同步收缩。由于胎儿状态不稳定，第一个双胞胎通过产钳分娩。右子宫有微弱收缩，但未进展到分娩。六天后，引产，第二个双胞胎也通过产钳出生。本病例对分娩起始和角间协调提供了罕见的临床见解。

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引用次数: 0

Associations Between Late-Night Shift Work and Perinatal Outcomes: A Nationwide Cross-Sectional Study Using JACSIS and JASTIS Data 深夜轮班工作与围产期结局之间的关系：一项使用JACSIS和JASTIS数据的全国性横断面研究。

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research

Pub Date : 2026-02-13 DOI: 10.1111/jog.70205

Yuya Tanaka, Yoshifumi Kasuga, Yoshihiko Hosokawa, Junko Tamai, Yuka Fukuma, Toshimitsu Otani, Marie Fukutake, Satoru Ikenoue, Takahiro Tabuchi, Mamoru Tanaka

Aim

This study investigated associations between late-night shift work and perinatal outcomes.

Methods

Participants were pregnant women with recorded perinatal outcomes (late-night shift group, 626 cases; non-late-night shift group, 6633 cases) identified from two Japanese Internet surveys. We analyzed the association between late-night shift work and adverse perinatal outcomes. Furthermore, we examined factors associated with the use of Maternal Health Management and Guidance Cards.

Results

The late-night shift group had significantly higher rates of threatened miscarriage, premature rupture of membranes (PROM), use of the Maternal Health Management and Guidance Card, health problems requiring hospitalization, fetal health problems, and infectious diseases compared with the non-late-night shift group. However, other perinatal outcomes, including preterm birth, gestational age at delivery, mode of delivery, and birth weight, did not differ significantly between groups. Among late-night shift-working mothers, those who used the Maternal Health Management and Guidance Card had a higher incidence of hyperemesis gravidarum, threatened miscarriage, and preterm labor than those who did not.

Conclusions

Late-night shift work during pregnancy may be associated with an increased risk of perinatal complications. The Maternal Health Management and Guidance Card may provide support for pregnant women engaged in late-night shift work.

目的：本研究探讨夜班工作与围产期结局之间的关系。方法：参与者是从两次日本互联网调查中确定的有围产期结局记录的孕妇（夜班组，626例；非夜班组，6633例）。我们分析了夜班工作与不良围产期结局之间的关系。此外，我们研究了与使用孕产妇健康管理和指导卡相关的因素。结果：与非夜班组相比，夜班组的先兆流产、胎膜早破、孕产妇健康管理和指导卡的使用、需要住院治疗的健康问题、胎儿健康问题和传染病的发生率显著高于夜班组。然而，其他围产期结局，包括早产、分娩胎龄、分娩方式和出生体重，在两组之间没有显著差异。在夜班工作的母亲中，那些使用孕产妇健康管理和指导卡的人比那些没有使用的人有更高的妊娠剧吐、先兆流产和早产的发生率。结论：妊娠期夜班工作可能与围产期并发症的风险增加有关。产妇保健管理和指导卡可为从事夜班工作的孕妇提供支持。

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引用次数: 0

Residual Oil-Based Contrast Medium Mimicking a Metallic Foreign Body After Cesarean Section: Diagnostic Value of AI-Assisted 3D CT Analysis and Prenatal MRI 剖宫产术后模拟金属异物的残油造影剂：ai辅助3D CT分析和产前MRI的诊断价值。

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research

Pub Date : 2026-02-12 DOI: 10.1111/jog.70203

Mizuho Fukuda, Kyosuke Kagami, Iwao Yasoshima, Takashi Iizuka, Saya Igarashi, Kaoru Abiko

A 36-year-old woman underwent an elective cesarean section at 37 weeks of gestation. A postoperative abdominal X-ray unexpectedly revealed a 20 mm hyperattenuating pelvic lesion. Computed tomography (CT) demonstrated a dense structure exceeding 3000 Hounsfield units with metallic-like artifacts, suggesting a retained metallic object. Intraoperative video review and instrument count confirmed no missing items. Three-dimensional CT reconstruction and open-source artificial intelligence (AI)–based shape analysis found no similarity to metallic instruments. Review of the patient's history revealed prior hysterosalpingography with oil-based iodinated contrast medium. Retrospective assessment of prenatal magnetic resonance imaging (MRI) showed a cystic lesion with high signal intensity on T₁- and T₂-weighted images, with signal suppression on fat-suppressed T₁-weighted imaging, consistent with fatty components. The lesion was diagnosed as a pseudocyst due to residual contrast medium. This case demonstrates that oil-based contrast can mimic metallic density, and that AI-assisted three-dimensional CT and MRI review can prevent unnecessary reoperation.

一位36岁的妇女在妊娠37周接受了选择性剖宫产手术。术后腹部x光片意外显示20毫米高衰减的盆腔病变。计算机断层扫描（CT）显示一个密集的结构，超过3000个霍斯菲尔德单位，并有金属样的伪影，表明保留了金属物体。术中视频检查及器械计数均无遗漏。三维CT重建和基于开源人工智能（AI）的形状分析发现与金属仪器没有相似之处。回顾患者的病史，发现先前使用油基碘造影剂进行子宫输卵管造影。产前磁共振成像（MRI）回顾性评估显示，囊性病变在T1和t2加权图像上具有高信号强度，在脂肪抑制的T1加权图像上具有信号抑制，与脂肪成分一致。由于造影剂残留，病变被诊断为假性囊肿。该病例表明，油基造影剂可以模拟金属密度，人工智能辅助的三维CT和MRI检查可以防止不必要的再次手术。

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引用次数: 0

Changes in Epithelial Ovarian Cancer Recurrence and Survival According to Treatment Paradigm Shifts 根据治疗模式的转变上皮性卵巢癌的复发和生存的变化。

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research

Pub Date : 2026-02-12 DOI: 10.1111/jog.70192

Jeongyun Kim, Dong Hoon Suh, Kidong Kim, Jae Hong No, Yong Beom Kim

Aim

To evaluate oncologic outcomes in patients with epithelial ovarian cancer (EOC) amid evolving surgical and systemic therapy paradigms.

Methods

This retrospective cohort study included patients diagnosed with EOC from June 2003 to December 2020 at a single tertiary center, grouped by diagnosis period. Overall survival (OS) and progression-free survival (PFS) were analyzed using the Kaplan–Meier and Cox regression analyses.

Results

A total of 763 patients were classified as 2003–2008 (Group 1, n = 101), 2009–2013 (Group 2, n = 207), and 2014–2020 (Group 3, n = 455), reflecting changes in cytoreductive surgery and targeted therapies (bevacizumab and PARP inhibitors). Early-stage diagnoses increased over time without statistical significance (Stage I–II: Group 1, 37.6% vs. Group 3, 46.6%; p = 0.200). Group 2 showed greater use of interval debulking surgery (IDS), higher complete cytoreduction rates, and more first-line chemotherapy cycles (all p < 0.001). Group 3 represented the introduction of targeted therapies (p < 0.001 for both). IDS with residual (< 1 cm) was associated with poorer outcomes than complete/optimal primary debulking surgery (PDS) (hazard ratio 2.94, 95% confidence interval 1.5–5.8). Despite unchanged PFS, the 5-year OS improved from 64.0% to 82.5% among patients with advanced-stage disease (p = 0.024).

Conclusions

Over two decades, with the advent of targeted therapies, complete cytoreduction (especially in PDS) has increased. Although the use of IDS also increased, residual disease (< 1 cm) after IDS was associated with poorer outcomes. While PFS remained unchanged, 5-year OS significantly improved among patients with advanced-stage disease diagnosed in the most recent period.

目的：评估上皮性卵巢癌（EOC）患者在不断发展的手术和全身治疗模式下的肿瘤预后。方法：本回顾性队列研究纳入了2003年6月至2020年12月在单一三级中心诊断为EOC的患者，按诊断期分组。采用Kaplan-Meier和Cox回归分析总生存期（OS）和无进展生存期（PFS）。结果：共有763例患者被分为2003-2008年（第1组，n = 101）， 2009-2013年（第2组，n = 207）和2014-2020年（第3组，n = 455），反映了细胞减少手术和靶向治疗（贝伐单抗和PARP抑制剂）的变化。早期诊断随时间增加，但无统计学意义（I-II期：第1组，37.6% vs.第3组，46.6%;p = 0.200）。第2组更多地使用间隔减体积手术（IDS），更高的完全细胞减少率，更多的一线化疗周期（均p）结论：在过去的二十年中，随着靶向治疗的出现，完全细胞减少（特别是PDS）增加。尽管IDS的使用也有所增加，但残留疾病(

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引用次数: 0

Fetal Growth Outcomes in Early Gestational Diabetes Mellitus Managed Immediately After Diagnosis 妊娠早期糖尿病诊断后立即处理的胎儿生长结局。

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research

Pub Date : 2026-02-11 DOI: 10.1111/jog.70199

Sayuri Nakanishi, Kei Miyakoshi, Maki Yokoyama, Yoshifumi Kasuga, Noriyuki Iwama, Hiroshi Yamashita, Shigeru Aoki, Ichiro Yasuhi, Takashi Sugiyama

Aim

To evaluate fetal growth outcomes in gestational diabetes diagnosed before 20 weeks' gestation (E-GDM) following immediate intervention and to identify factors associated with abnormal fetal growth.

Methods

We retrospectively analyzed singleton term pregnancies with E-GDM between 2016 and 2021 at two university hospitals in Japan: Keio University Hospital (KUH) and Yokohama City University Medical Center (YCUMC). Dietary management was initiated immediately after diagnosis in both hospitals. At KUH, all E-GDM women underwent self-monitoring of blood glucose (SMBG). At YCUMC, the indication for SMBG was determined based on pre-pregnancy weight, the number of abnormal values on the oral glucose tolerance test, and other glycemic biomarkers, including HbA1c and glycated albumin. Fetal growth outcomes, assessed as the proportions of large-for-gestational-age (LGA) and small-for-gestational-age (SGA), were evaluated in E-GDM receiving early management.

Results

Among 509 pregnancies (190 at KUH and 319 at YCUMC), LGA and SGA were observed in 63 (12%) and 46 (9%), respectively. The proportion of LGA was not significantly associated with pre-pregnancy BMI (underweight, 9.6%; normal, 11%; overweight/obese, 16%: p = 0.20). In contrast, there was a significant difference in the proportion of SGA among the three groups (underweight, 19%; normal, 8.2%; overweight/obese, 7.2%: p = 0.024). Multivariate analysis demonstrated that pre-pregnancy underweight was significantly associated with SGA in comparison with pre-pregnancy normal weight.

Conclusions

Fetal growth outcomes in E-GDM receiving early intervention were comparable to that of uncomplicated Japanese pregnancies. Since pre-pregnancy underweight remained a risk factor of SGA, clinicians should pay attention to the development of SGA in lean women with E-GDM.

目的：评价妊娠20周前诊断为妊娠糖尿病（E-GDM）的患者在立即干预后的胎儿生长结局，并确定与胎儿异常生长相关的因素。方法：我们回顾性分析了2016年至2021年间日本两所大学医院（庆应义塾大学医院（KUH）和横滨市立大学医学中心（YCUMC））的单胎足月妊娠E-GDM。两家医院在确诊后立即开始了饮食管理。在KUH，所有E-GDM女性都进行了自我血糖监测（SMBG）。在YCUMC， SMBG的适应症是根据孕前体重、口服葡萄糖耐量试验异常值的数量以及其他血糖生物标志物（包括HbA1c和糖化白蛋白）来确定的。在接受早期治疗的E-GDM中，以大胎龄（LGA）和小胎龄（SGA）的比例评估胎儿生长结局。结果：509例妊娠（KUH 190例，YCUMC 319例）中，LGA 63例（12%），SGA 46例（9%）。LGA比例与孕前BMI无显著相关性（体重过轻，9.6%；正常，11%；超重/肥胖，16%:p = 0.20）。相比之下，三组之间SGA的比例有显著差异（体重过轻，19%；正常，8.2%；超重/肥胖，7.2%,p = 0.024）。多因素分析表明，与孕前正常体重相比，孕前体重不足与SGA有显著相关性。结论：接受早期干预的E-GDM患者的胎儿生长结局与未并发症的日本妊娠相当。由于孕前体重过轻仍然是SGA的危险因素，临床医生应重视消瘦的E-GDM女性SGA的发展。

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引用次数: 0

Impact of Enoxaparin on Hemoglobin and Platelet Parameters in Post-Cesarean Venous Thromboembolism Prophylaxis: A Retrospective Cohort Study 依诺肝素对剖宫产后静脉血栓栓塞预防中血红蛋白和血小板参数的影响：一项回顾性队列研究

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research

Pub Date : 2026-02-10 DOI: 10.1111/jog.70200

Emrah Dagdeviren, Can Tercan, Ali Selcuk Yeniocak, Nisa Sari, Seyda Buyuk, Elif Ataseven, Onur Arabaci

Aim

To evaluate the effects of a 10-day postpartum enoxaparin regimen on hemoglobin (HB) levels and platelet indices in women receiving post-cesarean venous thromboembolism (VTE) prophylaxis.

Methods

This retrospective cohort study was conducted at a tertiary care center between December 2022 and June 2025. A total of 141 women who underwent cesarean section and had available hemogram data on postoperative day 10 were included. Patients were categorized into those who received enoxaparin prophylaxis (n = 112) and those who did not (n = 29). HB, hematocrit (HCT), platelet count (PLT), plateletcrit (PCT), mean platelet volume (MPV), platelet distribution width (PDW), and platelet large cell ratio (PLCR) were evaluated preoperatively, at 6 h postoperatively, and on the 10th postoperative day. The difference between postoperative 10th day and postoperative 6th hour laboratory values was also analyzed among groups receiving no enoxaparin, 40, or 60 mg/day of enoxaparin.

Results

No statistically significant differences were observed between the enoxaparin and non-enoxaparin groups in HB or platelet parameters on the 10th postoperative day (p > 0.05). The differences in hematologic indices between the 10th postoperative day and the 6th postoperative hour did not show significant variation among the dosing groups.

Conclusion

In our study, we did not observe a significant effect of a 10-day enoxaparin regimen used for postoperative VTE prophylaxis in cesarean patients on HB levels or platelet indices. However, given our limited sample size, its hematologic safety should be confirmed through larger prospective studies.

目的：评价产后10天依诺肝素治疗方案对剖宫产后静脉血栓栓塞（VTE）预防妇女血红蛋白（HB）水平和血小板指数的影响。方法：这项回顾性队列研究于2022年12月至2025年6月在一家三级保健中心进行。共有141名接受剖宫产手术并在术后第10天有可用血象资料的妇女被纳入研究。患者分为接受依诺肝素预防治疗组（n = 112）和未接受依诺肝素预防治疗组（n = 29）。术前、术后6 h及术后第10天分别评估HB、红细胞压积（HCT）、血小板计数（PLT）、血小板电积（PCT）、平均血小板体积（MPV）、血小板分布宽度（PDW）、血小板大细胞比（PLCR）。术后第10天和术后第6小时实验室值的差异还分析了未给予依诺肝素、40和60 mg/天依诺肝素组。结果：术后第10天，依诺肝素组与非依诺肝素组的HB、血小板参数比较，差异均无统计学意义（p < 0.05）。各给药组术后第10天至第6小时血液学指标差异无统计学意义。结论：在我们的研究中，我们没有观察到用于剖宫产患者术后静脉血栓栓塞预防的10天依诺肝素方案对HB水平或血小板指数的显著影响。然而，鉴于我们有限的样本量，其血液学安全性应通过更大的前瞻性研究来证实。

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引用次数: 0

Correction to “Development and Psychometric Properties of the Human Papillomavirus-Know Questionnaire (HPV-Know-Q) to Assess the Knowledge of Women on HPV Infection and Related Outcomes” 修正“人类乳头瘤病毒知识问卷（HPV- know - q）的发展和心理测量特性，以评估妇女对HPV感染及其相关结果的了解”。

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research

Pub Date : 2026-02-10 DOI: 10.1111/jog.70196

C. González-Granados, J. Rejas-Gutiérrez, J. Calvo-Torres, et al., “ Development and Psychometric Properties of the Human Papillomavirus-Know Questionnaire (HPV-Know-Q) to Assess the Knowledge of Women on HPV Infection and Related Outcomes,” Journal of Obstetrics and Gynaecology Research 52, no. 1 (2026): e70154, https://doi.org/10.1111/jog.70154.

Javier F. Garcia-Santos's affiliation has been incorrectly published online as follows:

¹Department of Obstetrics and Gynaecology, Hospital Quirónsalud, Málaga, Spain and ³Women Health Institute, Hospital Clínico San Carlos, IdISSC School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.

The correct affiliation should only be ³Women Health Institute, Hospital Clínico San Carlos, IdISSC School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.

We apologize for this error.

C. González-Granados， J. rejas - gutimacrirez， J. Calvo-Torres，等，“人类乳头瘤病毒知晓问卷（HPV- know - q）的发展和心理测量特性评估妇女对HPV感染和相关结果的了解”，《妇产科研究杂志》52，no. 1。1 (2026): e70154, https://doi.org/10.1111/jog.70154。Javier F. Garcia-Santos的隶属关系在网上被错误地发布如下：1西班牙Quirónsalud Málaga医院妇产科和3西班牙马德里康普顿斯大学IdISSC医学院Clínico圣卡洛斯医院妇女健康研究所。正确的隶属关系应该是西班牙马德里康普顿斯大学IdISSC医学院3妇女健康研究所Clínico圣卡洛斯医院。我们为这个错误道歉。

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引用次数: 0

Cervical Cerclage at 17 Gestational Weeks for Delayed-Interval Delivery at 15 and 27 Weeks of Gestation in a Dichorionic Twin Pregnancy: A Case Report 双绒毛膜双胎妊娠15和27周延迟分娩的17孕周宫颈环扎术：1例报告。

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research

Pub Date : 2026-02-05 DOI: 10.1111/jog.70193

Motomu Suzuki, Toshiyuki Itai, Ryosuke Shindo, Nozomi Maruiwa, Sayaka Suzuki, Natsumi Ono, Azusa Tochio, Kazunori Mukaida, Soichiro Obata, Etsuko Miyagi, Shigeru Aoki

Delayed-interval delivery refers to the delivery of the remaining fetus(es) at least 24 h after the delivery of the first fetus. There have been limited case reports of delayed-interval deliveries in twin pregnancies whose delivery of the first twin occurred in the early second trimester. We report a delayed-interval delivery of a dichorionic diamniotic pregnancy complicated by multiple fibroids. A 38-year-old primipara woman delivered the first twin at 15 weeks and 3 days of gestation. She did not have uterine contractions or any signs of infection, then McDonald cerclage was performed at 17 weeks and 1 day of gestation. At 27 weeks and 2 days of gestation, the second twin, 922 g, was delivered by caesarean section after premature rupture of membranes. Delayed-interval delivery may be considered in the early second trimester if there is no evidence of uterine contractions or infection, even in patients at risk for preterm birth.

延迟间隔期分娩是指在第一胎分娩后至少24小时才分娩剩余胎儿。有有限的病例报告延迟间隔分娩的双胞胎妊娠，分娩的第一个双胞胎发生在早期中期妊娠。我们报告一个延迟间隔分娩的双绒毛膜双羊膜妊娠合并多发性肌瘤。一位38岁的初产妇在妊娠15周零3天分娩了第一个双胞胎。无子宫收缩及感染症状，妊娠17周1天行McDonald环切术。在妊娠27周零2天，第二个922克的双胞胎在胎膜早破后剖腹产分娩。如果没有子宫收缩或感染的证据，即使是有早产风险的患者，也可以考虑在妊娠中期早期延迟分娩。

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引用次数: 0