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Prevalence of Staphylococcus aureus among Female Patients Attending Rivers State University Teaching Hospital (RSUTH) in Port Harcourt, Nigeria 尼日利亚哈科特港河流州立大学教学医院(RSUTH)女性患者中金黄色葡萄球菌的患病率
Pub Date : 2023-04-19 DOI: 10.9734/ajrid/2023/v13i1255
D. E. Adirimo, Nedie Patience Akani, T. Sampson
Objectives: To isolate, identify and determine the prevalence of Staphylococcus aureus among Female Patients attending Rivers State University Teaching Hospital in Port Harcourt using High Vaginal Swab samples. Methods: A cross-sectional study was carried out on total of 103 female patients attending the outpatients department and Antenatal clinic of Rivers State University Teaching Hospital. High Vaginal Swab samples were aseptically collected from 55 non-pregnant and 48 six weeks postpartum women. These were then analysed in the Microbiology Laboratory of the Hospital, following standard microbiological procedures. Questions on age, number of sexual partners, knowledge of vaginal infection, symptomatic case, History of previous infection and treatments was responded to by each participant through the completing of questionnaires. Mannitol Salt Agar (MSA) was used for the isolation of the organism and their phenotypic traits were determined based on their cultural and biochemical characteristics. Results: The study revealed that 25 (24.3%) consisting of 20 (36.4%) non-pregnant women and 5 (10.4%) Postpartum women were positive for Staphylococcus aureus infection. The prevalence of S. aureus among different groups was statistically significant, (P= .002). The highest percentage of S. aureus isolation (36.4%) was found in non-pregnant population. Prevalence of S. aureus was found highest 10 (18.2%) in 21-25 age group among non-pregnant women and none in 26-30 age group among postpartum women. Data obtained from the questionnaires returned showed that 10 (40%) that tested positive for the organism were asymptomatic as at the time of sample collection, had history of previous reproductive tract infection and had previously undergone treatment.   Conclusion: The high rate of vaginal Staphylococcal colonisation observed and the positive correlation between Staphylococus aureus prevalence and age, Child delivery status as well as treatment of previous reproductive tract infection seen in the study suggests the need for awareness on the importance of personal hygiene, proper antibiotic usage and regular screening of females within reproductive age.
目的:分离、鉴定并测定哈科特港河流州立大学教学医院女性患者中金黄色葡萄球菌的流行情况。方法:对江河州立大学教学医院门诊和产前门诊103例女性患者进行横断面研究。无菌收集55名未怀孕妇女和48名产后6周妇女的高阴道拭子样本。然后在医院微生物实验室按照标准微生物学程序进行分析。每位参与者通过填写问卷回答年龄、性伴侣数量、阴道感染知识、症状、既往感染史和治疗情况等问题。采用甘露醇盐琼脂(MSA)对病原菌进行分离,并根据培养和生化特性测定其表型性状。结果:本研究结果显示,25例(24.3%)未怀孕妇女20例(36.4%),产后妇女5例(10.4%)金黄色葡萄球菌感染阳性。各组金黄色葡萄球菌感染率差异有统计学意义(P= 0.002)。非妊娠人群金黄色葡萄球菌分离率最高(36.4%)。金黄色葡萄球菌在非妊娠妇女中21-25岁年龄组患病率最高(18.2%),在产后妇女中26-30岁年龄组无。从返回的问卷中获得的数据显示,10名(40%)微生物检测呈阳性的患者在采集样本时无症状,既往有生殖道感染史,并曾接受过治疗。结论:本研究中观察到的阴道葡萄球菌定植率高,金黄色葡萄球菌患病率与年龄、分娩状况以及既往生殖道感染治疗呈正相关,提示有必要认识到个人卫生、正确使用抗生素和定期筛查育龄妇女的重要性。
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引用次数: 0
The Association of Hepatitis B and Polymyositis: Rare but Real 乙型肝炎与多发性肌炎的关系:罕见但真实
Pub Date : 2023-04-13 DOI: 10.9734/ajrid/2023/v13i1254
Kavita Chaudhry, G. Kaur, Priyanshu Kumar
Aims: Hepatitis B virus infection is a global health concern. Although Hepatitis B virus primarily affects hepatocytes, it sometimes develops disease manifestations outside the liver and can present as full fledged proximal myopathy.  Presentation of Case: We report a 68-year-old man presenting with progressive proximal bilateral lower limb weakness for the last 14 days. The weakness was associated with pain and one episode of fever. Examination revealed 3/5 power in the shoulder and hip joint without any sensory deficit. Biochemical investigation showed elevated CPK levels (1102 IU/L) and liver enzymes (AST – 625 IU/L, ALT – 356 IU/L). HBsAg and HBeAg came out to be positive with HBV DNA of 73000 copies/mL. MRI shoulder and hip joints revealed diffuse intramuscular and myofascial edema suggesting inflammatory myositis. Muscle biopsy was suggestive of Necrotizing Autoimmune Myopathy. Discussion: Patient symptoms improved after starting IV Prednisolone and Entecavir therapy suggesting a close association between Hepatitis B infection and myopathy. Conclusion: Although Hepatitis B virus primarily affects hepatocytes, it sometimes develops disease manifestations outside the liver, such as Polymyositis. Therefore, it is imperative to screen for Viral markers in these patients.
目的:乙型肝炎病毒感染是一个全球性的健康问题。虽然乙型肝炎病毒主要影响肝细胞,但有时在肝外出现疾病表现,并可表现为完全的近端肌病。病例介绍:我们报告一位68岁的男性,在过去的14天里表现为进行性双侧下肢近端无力。虚弱伴有疼痛和一次发热。检查显示肩部和髋关节有3/5的力量,没有感觉障碍。生化检查显示CPK水平升高(1102 IU/L),肝酶水平升高(AST - 625 IU/L, ALT - 356 IU/L)。HBsAg、HBeAg阳性,HBV DNA为73000拷贝/mL。肩关节和髋关节MRI显示弥漫性肌内和肌筋膜水肿提示炎症性肌炎。肌肉活检提示坏死性自身免疫性肌病。讨论:开始静脉注射强的松龙和恩替卡韦治疗后,患者症状有所改善,提示乙型肝炎感染与肌病密切相关。结论:乙型肝炎病毒虽然主要影响肝细胞,但有时也会出现肝外病变表现,如多发性肌炎。因此,筛查这些患者的病毒标志物是必要的。
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引用次数: 1
Relationship between Premature Rupture of the Membrane and Cesarean Delivery: Case from Jakarta, Indonesia 胎膜早破与剖宫产的关系:印度尼西亚雅加达一例
Pub Date : 2023-04-11 DOI: 10.9734/ajrid/2023/v12i4253
Premature rupture of membranes (PROM) is the spontaneous rupture of the membranes before the onset of signs of labor. It can occur both before term (<37 weeks) and after term (> 37 weeks). Caesarean delivery is a surgical technique to deliver the fetus through an incision in the abdominal wall and uterine wall. This procedure is performed to minimize all complications from premature rupture of membranes. This study aims to determine the relationship between premature rupture of membranes and delivery of sectio caesarea at the UKI General Hospital in the 2019 period by using a descriptive content analysis method (analysis of medical records documents) with a cross-sectional approach and obtained 65 samples who experienced premature rupture of membranes. The results showed that 53 samples (81.55%) experienced premature rupture of membranes and performed sectio caesarea, while 12 samples (18.45%) had premature rupture of membranes but did not perform sectio caesarea with p-value = 0.001 (p <0.05) from the results of the chi-square statistical test. From the results of the analysis, it was found that there was a relationship between premature rupture of membranes and delivery of cesarean section at the UKI General Hospital for the 2019 period. It is suggested that patients avoid the factors that can cause premature rupture of the membranes, which have been told by the doctor or health worker and the patient's family to support the patient to remind them to avoid factors that can cause premature rupture of the membranes.
早破胎膜(PROM)是自发破裂的膜发作前的劳动迹象。它可以发生在足月前(37周)。剖宫产是一种通过腹壁和子宫壁切口分娩胎儿的手术技术。该手术是为了尽量减少胎膜过早破裂的并发症。本研究旨在通过横断面方法的描述性内容分析方法(病历文件分析),确定2019年期间在UKI综合医院发生的胎膜早破与剖宫产的关系,并获得65例胎膜早破的样本。结果显示,53例(81.55%)发生胎膜早破并行剖宫产术,12例(18.45%)发生胎膜早破但未行剖宫产术,χ 2检验的p值= 0.001 (p <0.05)。从分析结果来看,2019年期间在UKI总医院进行的剖宫产手术与胎膜早破之间存在关系。建议患者尽量避免可能导致胎膜早破的因素,已由医生或卫生工作者告知,患者家属支持患者,提醒其避免可能导致胎膜早破的因素。
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引用次数: 0
Circulation of Rotavirus Genotypes and their Distribution among Vaccinated and Non-vaccinated Children in Abuja, Nigeria 尼日利亚阿布贾轮状病毒基因型的传播及其在接种疫苗和未接种疫苗儿童中的分布
Pub Date : 2023-04-05 DOI: 10.9734/ajrid/2023/v12i4252
B. Balarabe-Musa
Introduction: Nigeria had planned to introduce the rotavirus vaccine in the National Immunisation Programme in 2014 but this has yet to be done. Nigeria has the continent’s highest mortality due to diarrhoeal diseases with little information on specific prevalent genotypes. The main objectives of the study were to identify the predominant rotavirus genotypes and to examine the effects of existing local vaccination programmes on prevailing rotavirus genotypes and on preventing rotavirus diarrhoea. Methodology: A one-year prospective descriptive study of children under 5 with acute diarrhoea was conducted from September 2012 to August 2013. Children with acute diarrhoea attending three government hospitals and one private hospital were recruited. Children without diarrhoea were also recruited as a control group. Rotavirus ELISA and RNA extraction were done with commercially available kits and positive samples were subjected to RT-PCR and electrophoresis to determine VP7 (G) and VP4 (P) genotypes. Results: Stool samples were collected from 1240 (93.3%) participants, of whom 957 (77.0%) were ambulatory, 123 (9.9%) hospitalised and 160 (12.8%) controls without diarrhoea. Rotavirus-ELISA was positive among 123 (11.4%) children with diarrhoea. The predominant VP7 genotypes were G2 (n=33, 26.4%) followed by G9 (n=24, 19.2). The main VP4 (P) genotypes included P [4] (n=45, 36.0%) followed by P [6] (n=40, 32.0%). The predominant genotype combinations found were G2 P [4] (n=21, 16.8%), G3 P [6] and G1 P [6] (each n=16, 12.8%), and G12 P [8] (n=15, 12.0%). Very few mixed infections were found in only one government hospital 4 (6.4%). Among 94 unvaccinated children with rotavirus isolates that were genotyped, G2 P [4] (n=19, 20.2%) and G1 P [6] (n=16, 17.0%) were predominant. Among 12 vaccinated children, 2 isolates each (16.6%) were found of G3 P [6], G9 P [4], G12 P [8] and G2 P [NT] with no G1 isolates. Conclusion: The emergence of new genotypes such as G 12 P [8] found in this study emphasizes the need for continued prospective monitoring of rotavirus at the molecular level to detect new threats to vaccine programmes in future.
导言:尼日利亚曾计划在2014年将轮状病毒疫苗纳入国家免疫规划,但这一计划尚未完成。尼日利亚是非洲大陆腹泻病死亡率最高的国家,而关于具体流行基因型的信息很少。该研究的主要目的是确定主要的轮状病毒基因型,并检查现有的地方疫苗接种规划对流行的轮状病毒基因型和预防轮状病毒腹泻的影响。方法:2012年9月至2013年8月对5岁以下急性腹泻患儿进行为期一年的前瞻性描述性研究。在三所政府医院和一所私立医院招募患有急性腹泻的儿童。没有腹泻的儿童也被招募为对照组。采用市售试剂盒对轮状病毒进行酶联免疫吸附试验和RNA提取,阳性样本进行RT-PCR和电泳检测VP7 (G)和VP4 (P)基因型。结果:收集了1240名(93.3%)参与者的粪便样本,其中957名(77.0%)是流动的,123名(9.9%)是住院的,160名(12.8%)是没有腹泻的对照组。123例(11.4%)腹泻患儿轮状病毒elisa阳性。VP7的优势基因型为G2 (n=33, 26.4%),其次为G9 (n=24, 19.2%)。VP4 (P)主要基因型为P [4] (n=45, 36.0%),其次为P [6] (n=40, 32.0%)。主要基因型组合为G2 P [4] (n=21, 16.8%)、G3 P[6]和G1 P[6](各n=16, 12.8%)和G12 P [8] (n=15, 12.0%)。只有一家政府医院4(6.4%)发现了极少数混合感染。在94例未接种疫苗的轮状病毒分离株中,G2 P [4] (n=19, 20.2%)和G1 P [6] (n=16, 17.0%)占主导地位。12例接种儿童中,G3 P[6]、G9 P[4]、G12 P[8]、G2 P [NT]各2株(16.6%),无G1分离株。结论:本研究中发现的g12p[8]等新基因型的出现,强调需要在分子水平上继续对轮状病毒进行前瞻性监测,以发现未来疫苗规划的新威胁。
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引用次数: 0
How is Bangladesh Growing More Susceptible to Infectious Disease Epidemics as a Result of Climate Change? A Systematic Review 气候变化如何使孟加拉国越来越容易受到传染病的影响?系统回顾
Pub Date : 2023-04-04 DOI: 10.9734/ajrid/2023/v12i4251
M. Noorunnahar, Maksuda Akter Mily, Lima Khatun, Md. Ashiqur Rahman, Rayhan Ahmmed Pranto, Khandoker Saif Uddin
Bangladesh is facing unpredictable weather patterns, as well as a consistent rise in temperature and precipitation. Climate change has had a negative impact on physical and mental health, leading to an increase mostly in the prevalence and variation of infectious diseases, as well as psychological issues such as depression and anxiety disorders. Given the country's inherent sensitivity to climatic influences, the climate-health nexus is a relatively unexplored subject of research. The purpose of this article is to investigate the severity of climate change in Bangladesh and how it impacts the health of the public. Morbidity and mortality due to heat stress, cyclones, floods, droughts, and other weather extremes at various spatiotemporal scales have been observed as direct effects of climate change in Bangladesh. The indirect effects involve more complicated paths, such as affecting food and water security due to salinity intrusion and the development of infectious diseases because of shifts in vector and pathogen ecology. To mitigate the effects of climate change on various infectious diseases, healthcare and response systems must be strengthened. By implementing proactive adaptation methods, we may significantly and actively contribute to preventing and regulating the negative consequences of climate change on human health. There is little evidence to make sound health policy decisions in the context of climate change, and there is a lack of multidisciplinary research activities. Despite these constraints, gathering and reporting scientific information is essential for developing a resilient health system in climate-vulnerable countries like Bangladesh and other low-income regions.
孟加拉国正面临着不可预测的天气模式,以及气温和降水的持续上升。气候变化对身心健康产生了负面影响,主要是导致传染病的流行率和多样性增加,以及抑郁症和焦虑症等心理问题的增加。鉴于这个国家对气候影响的固有敏感性,气候与健康的关系是一个相对未被探索的研究课题。本文的目的是调查孟加拉国气候变化的严重程度,以及它如何影响公众的健康。在孟加拉国,由于各种时空尺度的热应激、旋风、洪水、干旱和其他极端天气造成的发病率和死亡率已被观察到是气候变化的直接影响。间接影响涉及更复杂的途径,例如由于盐度入侵而影响粮食和水安全,以及由于媒介和病原体生态的变化而导致传染病的发展。为了减轻气候变化对各种传染病的影响,必须加强卫生保健和应对系统。通过实施积极主动的适应方法,我们可以为预防和调节气候变化对人类健康的负面影响作出重大和积极的贡献。几乎没有证据表明在气候变化的背景下做出合理的卫生政策决定,而且缺乏多学科研究活动。尽管存在这些限制,收集和报告科学信息对于在孟加拉国等易受气候影响的国家和其他低收入地区建立具有抵御力的卫生系统至关重要。
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引用次数: 0
Burden of Rotavirus Diarrhoea in Children in Abuja 阿布贾儿童轮状病毒腹泻负担
Pub Date : 2023-03-30 DOI: 10.9734/ajrid/2023/v12i4250
B. Balarabe-Musa
Background: Diarrhoea is the second leading cause of death in children. Nigeria has the continent’s highest mortality due to diarrhoeal diseases with little information on specific causes and the proportion affected by rotavirus infection. The main objectives of this study were to describe the features of young children with diarrhoea, with and without rotavirus, in Abuja the Federal Capital Territory. Materials and Methods: Retrospective review of local hospital activity data related to diarrhoea was retrieved from General Hospitals in Abuja. Then a one-year prospective descriptive study of children under 5 years of age with acute diarrhoea was conducted from September 2012 to August 2013. Children with acute diarrhoea attending three government hospitals and one private hospital were recruited. Children without diarrhoea were recruited as the control group. Faecal specimens were transported in cold chain boxes from Nigeria and stored at -80 °C at the Institute of Global Health, virology section of the University of Liverpool, where all laboratory work was performed. Results: Hospital records were poorly preserved and did not provide meaningful data for trend analyses or disease surveillance. 1331 participants were enrolled in this prospective study. Stool samples were collected from 1242 (93.3%) participants, of whom 957 (77.0%) were ambulatory, 123 (9.9%) hospitalised and 160 (12.8%) controls without diarrhoea. 881 and 450 children with diarrhoea were recruited from government and the private hospitals, respectively. The median age of the children was 8 months in the ambulatory and 9.5 months in the hospitalized group (p<0.05). A total of 209 (16.8%) children were vaccinated, 858 (69.1%) were unvaccinated, and 174 (14.0%) had an unclear vaccination status. Rotavirus ELISA was positive in 123 (11.4%) children with diarrhoea and 2 (1.2%) controls. Among children with diarrhoea, 92 (10.4%) of 881 children attending government hospitals had rotavirus, compared to 33 (7.3%) of 450 children attending a private hospital (p<0.001) where a vaccination program had been in place. The peak months for rotavirus infection were November and February. The efficacy of Rotarix® RV1 vaccine in preventing rotavirus diarrhoea was indirectly assessed to be 64.5%. Conclusion: Rotavirus is an important pathogen in children, especially in unvaccinated children in Abuja. The introduction of a rotavirus vaccine is highly desirable in Nigeria, but this is still awaited. Local and national infrastructure are inadequate for basic surveillance of diarrhoeal disease, and this will have to be improved, together with access to virological stool testing, to monitor the planned vaccine program. The retrospective studies reported here provide indirect evidence of vaccine efficacy in Abuja but need prospective confirmation.
背景:腹泻是儿童死亡的第二大原因。尼日利亚是非洲大陆腹泻病死亡率最高的国家,但关于具体病因和轮状病毒感染比例的信息很少。这项研究的主要目的是描述联邦首都地区阿布贾患有和不患有轮状病毒腹泻的幼儿的特征。材料和方法:从阿布贾综合医院检索与腹泻有关的当地医院活动数据进行回顾性审查。随后于2012年9月至2013年8月对5岁以下急性腹泻患儿进行为期一年的前瞻性描述性研究。在三所政府医院和一所私立医院招募患有急性腹泻的儿童。没有腹泻的儿童作为对照组。来自尼日利亚的粪便标本用冷链箱运输,并在利物浦大学全球卫生研究所病毒学部门-80°C下保存,所有实验室工作都在那里进行。结果:医院记录保存不良,不能为趋势分析或疾病监测提供有意义的数据。1331名参与者参加了这项前瞻性研究。收集了1242名(93.3%)参与者的粪便样本,其中957名(77.0%)是流动的,123名(9.9%)是住院的,160名(12.8%)是没有腹泻的对照组。从政府医院和私立医院分别招募了881名和450名腹泻儿童。门诊组患儿平均年龄为8个月,住院组患儿平均年龄为9.5个月(p<0.05)。共有209名(16.8%)儿童接种疫苗,858名(69.1%)儿童未接种疫苗,174名(14.0%)儿童接种情况不明确。腹泻患儿123例(11.4%)和对照组2例(1.2%)轮状病毒ELISA检测呈阳性。在患有腹泻的儿童中,在公立医院就诊的881名儿童中有92名(10.4%)患有轮状病毒,而在已实施疫苗接种计划的私立医院就诊的450名儿童中有33名(7.3%)患有轮状病毒(p<0.001)。轮状病毒感染的高峰期是11月和2月。经间接评估,Rotarix®RV1疫苗预防轮状病毒腹泻的有效性为64.5%。结论:轮状病毒是阿布贾儿童,特别是未接种疫苗儿童的重要病原体。尼日利亚非常希望引进轮状病毒疫苗,但这仍在等待中。地方和国家的基础设施不足以对腹泻病进行基本监测,必须改善这一点,并提供病毒学粪便检测,以监测计划中的疫苗规划。这里报告的回顾性研究提供了疫苗在阿布贾效力的间接证据,但需要前瞻性证实。
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引用次数: 0
Prevalence of Perceived Anxiety in General People, Students and Healthcare Professionals during COVID-19 Pandemic: A Comprehensive Scientific Review 在COVID-19大流行期间,普通人群、学生和医疗保健专业人员的感知焦虑患病率:一项全面的科学综述
Pub Date : 2023-03-16 DOI: 10.9734/ajrid/2023/v12i4249
M. Nayan, Tirtha Nandi, R. Ghosh
The global severity of COVID-19 remains high which results anxiety and other mental health problems, also it altered people's everyday lives, affected human connections and economic operations. The goal of this comprehensive review was to identify the effects of the linkage COVID-19 pandemic on the mental health of different groups and communities. This study compiled evidences of a link between anxiety rates and the COVID-19 pandemic. The evaluation period started in June’ 2022 and ended on August’2022, during this time, total four databases such as PubMed, Science Direct, Tailor & Francis Online, and Springer were used to search scientific literatures. A total 616 studies were identified from all four databases and 63 scientific literatures were selected based of predetermined criteria for review which were published in between 2020 to 2022. Three groups of population such as general population, students and healthcare professionals were taken for review the findings from the selected literatures. Gender, physical disorders, psychiatric disorders, COVID infection, infection rates in colleagues or family members, experience of frontline work & non-frontline work, close contact with infected patients, high exposure risk, quarantine experience, etc. were highly considered as factors associated with increased prevalence of anxiety among all three groups. During the COVID-19 pandemic, the general population, healthcare professionals, and students experienced an increase in the prevalence of mental diseases, whereas infected individuals had a decrease. Females were highly prevalent to anxiety than male. Our comprehensive review concluded significant co-relation between anxiety and COVID-19 but long-term study is needed to better understand which may define the population's mental condition in future.
COVID-19的全球严重程度仍然很高,导致焦虑和其他精神健康问题,也改变了人们的日常生活,影响了人际关系和经济运作。这项综合综述的目的是确定COVID-19大流行对不同群体和社区心理健康的影响。这项研究收集了焦虑率与COVID-19大流行之间存在联系的证据。评估期从2022年6月开始至2022年8月结束,在此期间,共使用PubMed、Science Direct、Tailor & Francis Online和Springer四个数据库检索科学文献。从所有四个数据库中共确定了616项研究,并根据预先确定的标准选择了63篇科学文献,这些文献发表于2020年至2022年之间。三组人群,如一般人群,学生和卫生保健专业人员被用于审查所选文献的研究结果。性别、身体障碍、精神障碍、COVID感染、同事或家庭成员感染率、一线和非一线工作经历、与感染患者密切接触、高暴露风险、隔离经历等被高度认为是三组患者焦虑患病率增加的相关因素。在2019冠状病毒病大流行期间,普通人群、卫生保健专业人员和学生的精神疾病患病率上升,而感染者的发病率下降。女性比男性更容易焦虑。我们的综合评价得出焦虑与COVID-19之间存在显着的相关关系,但需要长期研究来更好地了解哪些因素可能决定未来人群的精神状况。
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引用次数: 0
Demographic and Public Health Characteristics of COVID-19 Mortality Cases in Rivers State, Nigeria –A Retrospective Cohort Study 尼日利亚河流州COVID-19死亡病例的人口统计学和公共卫生特征:回顾性队列研究
Pub Date : 2023-03-02 DOI: 10.9734/ajrid/2023/v12i3248
G. Owhonda, Foster Patrick, C. Eze-Emiri, Ezinne Igwe, G. Arugu, Ihuoma Des-Wosu, Victor Oris-Onyiri, Justice Ohaka, I. Nwadiuto
Introduction: COVID-19 has accounted for approximately six million deaths globally. Several risk factors have been identified. However, the population profile varies in different population groups. The study's aim is to describe the population profile of COVID-19 mortality in Rivers State, Nigeria using captured population-based health records.Methods: Using electronic State Health Records, secondary data analysis was conducted on recorded COVID-19 mortality. Data were obtained from the Public Health Emergency Operations Centre (PHEOC) at the State Ministry of Health, Rivers State. Data were accessed from the PHEOC database, and it included COVID-19 related mortality. Data were collected on demographics, pre-existing comorbidity, symptoms, facility managed, patient status, treatment outcome, and dates of related events. Cohort characteristics were described using means and proportions.Results: There were 191 COVID-19 deaths identified. The mean age was 57.08 years, of which 144 were male (75.4%). The 51–65-year age group had the highest mortality count (38.9%). Over 50% of the patients were hypertensive, and diabetes was the second most common comrbidity (28.8%). Running nose, cough, fever and breathing difficulties were the most reported COVID-19 symptoms.Conclusion: This study found that COVID-19 was responsible for a greater mortality increase in men and that the prevalence of hypertension and diabetes was higher in these individuals. Additionally, age and the presence of comorbidities may be associated with COVID-19 mortality. Future research in this area could further explain these findings.
导言:COVID-19已导致全球约600万人死亡。已经确定了几个风险因素。然而,不同人口群体的人口概况各不相同。该研究的目的是利用以人口为基础的健康记录,描述尼日利亚河流州COVID-19死亡率的人口概况。方法:利用电子健康档案对已记录的COVID-19死亡率进行二次资料分析。数据来自河流州卫生部公共卫生应急行动中心(PHEOC)。从PHEOC数据库中获取数据,其中包括COVID-19相关死亡率。收集的数据包括人口统计学、已存在的合并症、症状、设施管理、患者状态、治疗结果和相关事件的日期。用均值和比例描述队列特征。结果:确认COVID-19死亡191例。平均年龄57.08岁,其中男性144人(75.4%)。51 ~ 65岁年龄组死亡率最高(38.9%)。超过50%的患者患有高血压,糖尿病是第二大常见疾病(28.8%)。流鼻涕、咳嗽、发烧和呼吸困难是报告最多的COVID-19症状。结论:本研究发现,COVID-19导致男性死亡率增加,这些人的高血压和糖尿病患病率更高。此外,年龄和合并症的存在可能与COVID-19死亡率有关。该领域的未来研究可以进一步解释这些发现。
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引用次数: 0
Knowledge, Attitudes and Practices (Kap) on Covid-19 of Students of the Faculty of Pharmacy of the University of Kisangani 基桑加尼大学药学院学生对Covid-19的知识、态度和做法(Kap
Pub Date : 2023-03-01 DOI: 10.9734/ajrid/2023/v12i3246
Issa Yakusu, Baroani Bikenge, P. Kitronza, Ossinga Bassandja, Mfuamba Kadima, Longombe Ahuka Nono, Mankulu N’Sila, B. Agasa
Objectives: This study aimed to determine the level of knowledge, attitudes and practices (KAP) of students of the Faculty of Pharmacy of the University of Kisangani. Methods: A cross-sectional descriptive study was undertaken among students of the Faculty of Pharmacy. KAPs on Covid-19 were assessed using a survey questionnaire. Results: Male students were predominant (50.8%). The majority of respondents were under or equal to 25 years old. The majority had sufficient knowledge (97.4%) provided mainly by television and radio. 63 respondents or 33.3% of cases did not know if the disease exists in Kisangani; and 88.9% had good practices regarding Covid-19. Conclusion: These results showed that most students have a good knowledge of Covid-19; they presented good practices as well as good attitudes.
目的:本研究旨在了解基桑加尼大学药学院学生的知识、态度和行为水平。方法:对药学院学生进行横断面描述性研究。采用调查问卷对Covid-19的kap进行评估。结果:男学生居多,占50.8%。大多数受访者年龄在25岁以下或以下。大多数人(97.4%)主要通过电视和广播获得足够的知识。63名答复者或33.3%的病例不知道基桑加尼是否存在这种疾病;88.9%的人对Covid-19采取了良好做法。结论:大多数学生对新冠肺炎有较好的认识;他们提出了良好的做法和良好的态度。
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引用次数: 0
A Review on Human Metapneumovirus and Human Bocavirus Associated with Acute Respiratory Tract Infections 与急性呼吸道感染相关的人偏肺病毒和人博卡病毒研究进展
Pub Date : 2023-03-01 DOI: 10.9734/ajrid/2023/v12i3247
H. Narayanan, B. Nandagopal, Mageshbabu Ramamurthy, Kumaran Vadivel
One of the significant causes of morbidity and mortality among young children in developing nations is acute respiratory tract infections (ARTIs). It is also highly contagious, widely prevalent, and transmissible from person to person. It risks young children, the elderly, and those with immune system disorders. Acute respiratory infections are thought to cause 2.6 million child deaths annually worldwide, according to the World Health Organization (WHO) [1]. Infections in children with human metapneumovirus (hMPV) and bocavirus (HBoV) are linked to a high prevalence of ARTIs. It has been determined that hMPV is the second-leading cause of infant bronchiolitis, after the respiratory syncytial virus (RSV), of upper and lower respiratory tract infections. Although HBoV was first discovered in children's airways, the high detection rates of other viral pathogens and the discovery of HBoV in stool raise doubts about the virus's significance in respiratory tract infections. According to the published literature, only a few studies have identified ARTIs or demonstrated the importance of early diagnosis and treatment of ARTIs. This review article aims to thoroughly explain the aetiology, epidemiology, clinical characteristics, diagnostic approaches, and management of hMPV and HBoV.
急性呼吸道感染(ARTIs)是发展中国家幼儿发病和死亡的重要原因之一。它还具有高度传染性,广泛流行,并可在人与人之间传播。它对幼儿、老年人和免疫系统疾病患者有风险。根据世界卫生组织(WHO)的数据,全球每年有260万儿童死于急性呼吸道感染。儿童感染人偏肺病毒(hMPV)和bocavavirus (HBoV)与ARTIs的高流行率有关。已经确定hMPV是婴儿毛细支气管炎的第二大原因,仅次于呼吸道合胞病毒(RSV),是上呼吸道和下呼吸道感染。虽然HBoV最早是在儿童呼吸道中发现的,但其他病毒病原体的高检出率和粪便中HBoV的发现使人们对该病毒在呼吸道感染中的意义产生了怀疑。根据已发表的文献,只有少数研究确定了ARTIs或证明了早期诊断和治疗ARTIs的重要性。本文旨在全面阐述hMPV和HBoV的病因、流行病学、临床特征、诊断方法和治疗。
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引用次数: 0
期刊
Asian Journal of Research in Infectious Diseases
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