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A Case Series on COVID-19 Associated Mucormycosis (CAM): Experience from a Tertiary Care Centre in India 2019冠状病毒病相关毛霉菌病(CAM)系列病例:来自印度三级保健中心的经验
Pub Date : 2023-05-20 DOI: 10.9734/ajrid/2023/v13i3267
Aishwarya Govindaswamy, Sowmya Sridharan, Raymond D Savio, S. Nambi, Adhithyan Rajendran
Aim: During the second wave of the COVID 19 pandemic, a life threatening fungal infection, mucormycosis have been detected in patients post COVID 19 disease. Commonly known as the ‘black fungus’ can causes tissue necrosis, inflammation and necrosis of the head and neck regions, paranasal sinuses, facial bones, orbits and it can also cause intracranial spread. In the current study we describe a series of cases of COVID 19 associated mucormycosis (CAM), the clinical presentations, risk factors, diagnosis, management and follow up experience from a tertiary care centre in India. Methods: This is a retrospective observational study conducted over a period of one year (April 2021 to April 2022) at our tertiary care centre. The diagnosis of COVID 19 was done by RT PCR (reverse transcription-polymerase chain reaction). The diagnosis of Mucormycosis was done by Histopathology and fungal cultures. The demographic details of the patients were retrieved from the medical records. Results: In the present study we report four cases of Rhino-orbital-cerebral Mucormycosis, three cases of Rhino-orbital Mucormycosis, two cases of Pulmonary Mucormycosis and one case of Disseminated Mucormycosis. All the patients had undergone extensive surgical debridement and received Liposomal Amphotericin B as initial antifungal medication and Posaconazole or Isavuconazole as step down therapy. Six patients responded to treatment while four patients did not have a favorable outcome and succumbed to the illness.   Conclusion: Mucormycosis is a deadly disease with high mortality and morbidity if not diagnosed and treated at an early stage. Factors like poor control of blood sugars, inadvertent use of corticosteroids, immune dysfunction due to COVID 19 can result in poor outcome of the disease despite aggressive treatment interventions.
目的:在第二波COVID - 19大流行期间,在COVID - 19疾病后的患者中发现了一种危及生命的真菌感染-毛霉病。这种俗称“黑木耳”的真菌会导致组织坏死、头颈部、鼻窦、面部骨骼和眼眶的炎症和坏死,还会导致颅内扩散。在当前的研究中,我们描述了来自印度三级医疗中心的一系列COVID - 19相关毛霉病(CAM)病例、临床表现、风险因素、诊断、管理和随访经验。方法:这是一项回顾性观察性研究,为期一年(2021年4月至2022年4月),在我们的三级保健中心进行。RT - PCR(逆转录聚合酶链反应)诊断新冠肺炎。毛霉病的诊断是通过组织病理学和真菌培养完成的。从医疗记录中检索了患者的人口统计详细信息。结果:本研究报告鼻-眶-脑毛霉病4例,鼻-眶毛霉病3例,肺毛霉病2例,弥散性毛霉病1例。所有患者均进行了广泛的手术清创,并给予两性霉素B脂质体作为初始抗真菌药物,泊沙康唑或依沙乌康唑作为降级治疗。6名患者对治疗有反应,而4名患者没有良好的结果并死于疾病。结论:毛霉病是一种病死率高、发病率高的疾病,如不及早诊断和治疗。尽管采取了积极的治疗干预措施,但血糖控制不良、无意中使用皮质类固醇、COVID - 19导致的免疫功能障碍等因素可能导致疾病的预后不佳。
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引用次数: 0
Relationship between Body Mass Index and Lumbar Disc Herniation in UKI General Hospital Jakarta, Indonesia 印度尼西亚雅加达UKI总医院体重指数与腰椎间盘突出症的关系
Pub Date : 2023-05-15 DOI: 10.9734/ajrid/2023/v13i3265
Patria Adri Wibhawa, Agus Yudawijaya, Aldo Vivavaldi Wairisal
Background: Nucleus Pulposus Herniation (NPH) is a disease in which the annulus fibrosus ruptures, causing the nucleus pulposus to protrude or bulge and press against the spinal canal, causing sciatic pain. One of the risk factors for Nucleus pulposus herniation was Body Mass Index (BMI). Objective: This study aim the relationship between BMI and the incidence of Lumbar Disc Herniation (LDH) patients at UKI General Hospital from January to June 2020. Methods: The subjects of the study were 24 patients with lumbar disc herniation who were treated at UKI General Hospital from January to June 2020 that were taken from medical records. Results: 63 samples were analyzed that obtained 24 (38.0%) patients with lumbar disc herniation, and patients with lumbar disc herniation with BMI ≥ 23 as many as 18 subjects (75.0%). Conclusion: There is no significant relationship between BMI and LDH patients at UKI General Hospital.
背景:髓核突出症(NPH)是一种纤维环破裂,髓核突出或突出压迫椎管,引起坐骨疼痛的疾病。身体质量指数(BMI)是髓核突出的危险因素之一。目的:研究2020年1 - 6月在UKI总医院进行的腰椎间盘突出症(LDH)患者BMI与发病率的关系。方法:研究对象为2020年1月至6月在UKI总医院就诊的24例腰椎间盘突出症患者。结果:共分析63份样本,获得24例(38.0%)腰椎间盘突出症患者,其中BMI≥23的腰椎间盘突出症患者多达18例(75.0%)。结论:协和总医院患者BMI与LDH无显著相关性。
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引用次数: 0
Aggravating Effects of Hepatitis E Virus Infection on Patients with Chronic Liver Disease in Ibn-Sina Hospital Sudan 苏丹Ibn-Sina医院慢性肝病患者戊型肝炎病毒感染的加重效应
Pub Date : 2023-05-15 DOI: 10.9734/ajrid/2023/v13i2264
A. Ismail, K. Enan, Abdel-Rahim M. El-Hussein, Hala Ibrahim, Hajar A. Gsemalseed, Abdelmonem Abdo
Background: Hepatitis E virus (HEV) is one of the most common causes of acute hepatitis. Sudan is considered as hyper-endemic for HEV. HEV infection in patients with preexisting chronic liver diseases (CLDs) has been reported to result in severe clinical manifestations and poor outcomes. However data on the role of HEV infection in worsening of pre-existing CLD are limited. Objective: To determine hepatitis E virus (HEV) infection and its effect on severity of CLD. Methods: A descriptive cross-sectional study that consecutively enrolled 87 CLD patients in Ibn-Sina Specialized Hospital was carried out during the period from August 2020 to December 2020. Data regarding demographics, CLD causes, clinical manifestations and comorbidities were collected. The screening for anti-HEV antibodies was performed in all patients by using enzyme linked immuno-sorbent assay (ELISA). Results: Hepatitis B virus (HBV) was the commonest etiology of chronic liver diseases being detected in 45/87(51.7%) patients. On the other hand;among all subjects; 43/87(49.4%) patients were HEV seropositive with anti-HEV Ig-G being detected in 32(36.8%) and concurrent anti-HEV Ig-M and Ig-G in 11(12.6%) patients. Jaundice (OR= 3.8, CI95%: 1.5-9.4; P. value=0.004), HCC (OR= 4.1, CI95%: 1.4-11.9; P. value=0.008), child-Pugh class-C (OR= 26, CI95%: 5.4-94.0; P. value=0.000) and child-Pugh class-B (OR= 5.3, CI95%: 1.6-17.0; P. value=0.000) were associated independently with anti-HEV positivity. Conclusion: The frequency of hepatitis E virus (HEV) among Sudanese patients with chronic liver disease (CLD) was considerably high (mainly past infection- Ig-G). Furthermore, HEV was associated with advanced liver failure statuses (child-Pugh class-B & C), jaundice, and hepatocellular carcinoma.
背景:戊型肝炎病毒(HEV)是急性肝炎最常见的病因之一。苏丹被认为是戊型肝炎高流行地区。既往存在慢性肝病(CLDs)的患者感染HEV会导致严重的临床表现和不良预后。然而,关于HEV感染在既往CLD恶化中的作用的数据有限。目的:了解戊型肝炎病毒(HEV)感染情况及其对慢性肝病严重程度的影响。方法:采用描述性横断面研究,于2020年8月至2020年12月连续入组Ibn-Sina专科医院CLD患者87例。收集有关人口统计学、CLD病因、临床表现和合并症的数据。采用酶联免疫吸附试验(ELISA)对所有患者进行抗hev抗体筛选。结果:乙型肝炎病毒(HBV)是慢性肝病最常见的病因,在87例患者中有45例(51.7%)被检出。另一方面,在所有科目中;43/87例(49.4%)患者HEV血清阳性,32例(36.8%)患者检测到HEV抗体- g, 11例(12.6%)患者同时检测到HEV抗体- m和igg - g。黄疸(OR= 3.8, CI95%: 1.5-9.4;p值=0.004),HCC (OR= 4.1, CI95%: 1.4-11.9;p值=0.008),child-Pugh c类(OR= 26, CI95%: 5.4-94.0;p值=0.000)和child-Pugh b类(OR= 5.3, CI95%: 1.6-17.0;p值=0.000)与抗hev阳性独立相关。结论:苏丹慢性肝病(CLD)患者戊型肝炎病毒(HEV)发病率较高(主要为既往感染igg - g)。此外,HEV与晚期肝衰竭状态(child-Pugh b级和C级)、黄疸和肝细胞癌相关。
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引用次数: 0
Study of Potential Utility of Predictive Laboratory Parameters for Early Triage of SARI Patients 预测实验室参数在急性呼吸道感染患者早期分诊中的潜在效用研究
Pub Date : 2023-05-13 DOI: 10.9734/ajrid/2023/v13i2263
Dogra Shruti, B. Taruna, S. C. Devendar, K. Vijay, Kaushik Rajnish, Achra Arvind
Introduction: The novel corona virus (COVID-19), which began in Wuhan, China, in December 2019, has been declared pandemic by the World Health Organization (WHO) on 11th March 2021. Till now, even when nations are in race for developing vaccine against COVID-19, diagnosing the cases and isolating them still remain the only way to contain the disease spread. Hence, effective triage of the suspected COVID 19 patients, becomes an effective tool in preventing disease spread, especially in developing nations. Simple hematological parameters like leukocyte counts, platelet counts, hemoglobin and parameters derived from complete blood counts namely NLR, derived NLR, PLR and liver function tests can be studied and analysed to differentiate COVID 19 patients from other non-COVID 19 Severe Acute Respiratory Illness (SARI) patients. These are the investigations at first point of contact with the patient and are relatively cost effective, keeping in mind the population of developing nations. Patients and Methods: Retrospective case control study conducted over a period of one month including 286 consecutive Severe Acute Respiratory Illness(SARI) patients admitted in a                  tertiary care hospital in Delhi. The patients were divided into COVID-19 positive and COVID-19 negative groups based on their results of reverse transcriptase-polymerase chain reaction (RT-PCR) for COVID-19. The demographic data, and routine hematological and biochemical parameters including derived parameters like Neutrophil lymphocyte ratio (NLR), derived NLR  ratio, Platelet lymphocyte ratio (PLR) and Prognostic nutrition index (PNI) were analyzed and compared between the two groups using SPSS version 23.0. A p value of <0.05 was considered significant. Results: The COVID-19 positive patients had a significantly higher lymphocyte percentage (p value=0.017) and Serum Glutamate Pyruvate Transaminase(SGPT)( p value=0.033), and a significantly lower Absolute Neutrophil Count (ANC)( p value= 0.023), NLR(p value=0.033) and platelet count(p valu=0.001). No significant difference in other haematological and biochemical parameters was found. Conclusion: NLR, platelet count, lymphocyte percentage and SGPT are the simple laboratory biomarkers of inflammation that can be utilized for screening and triage in COVID 19 disease with variable sensitivity and specificity.
2019年12月在中国武汉爆发的新型冠状病毒(COVID-19)已于2021年3月11日被世界卫生组织(世卫组织)宣布为大流行。到目前为止,即使各国都在竞相开发针对COVID-19的疫苗,诊断和隔离病例仍然是遏制疾病传播的唯一途径。因此,对疑似COVID - 19患者进行有效的分类,成为防止疾病传播的有效工具,特别是在发展中国家。可以研究和分析简单的血液学参数,如白细胞计数、血小板计数、血红蛋白和全血细胞计数的参数,即NLR、衍生NLR、PLR和肝功能检查,以区分COVID - 19患者与其他非COVID - 19严重急性呼吸系统疾病(SARI)患者。这些是在与患者第一次接触时进行的调查,考虑到发展中国家的人口,这些调查相对而言具有成本效益。患者和方法:在为期一个月的回顾性病例对照研究中,包括286名在德里一家三级医院住院的连续严重急性呼吸系统疾病(SARI)患者。根据COVID-19逆转录聚合酶链反应(RT-PCR)结果将患者分为COVID-19阳性组和COVID-19阴性组。采用SPSS 23.0对两组患者的人口学数据、衍生参数中性粒细胞淋巴细胞比率(NLR)、衍生NLR比率、血小板淋巴细胞比率(PLR)、预后营养指数(PNI)等常规血液学及生化指标进行分析比较。p值<0.05为显著性。结果:COVID-19阳性患者淋巴细胞百分比(p值=0.017)、血清谷氨酸丙酮酸转氨酶(SGPT)(p值=0.033)显著高于对照组,绝对中性粒细胞计数(ANC)(p值= 0.023)、NLR(p值=0.033)和血小板计数(p值=0.001)显著低于对照组。其他血液学和生化指标无显著差异。结论:NLR、血小板计数、淋巴细胞百分比和SGPT是简单的炎症实验室生物标志物,可用于COVID - 19疾病的筛查和分诊,具有不同的敏感性和特异性。
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引用次数: 0
Outbreak of Cholera in Ghana: A Systematic Review from 2010 to 2020 加纳霍乱暴发:2010年至2020年的系统回顾
Pub Date : 2023-05-08 DOI: 10.9734/ajrid/2023/v13i2261
J. Apenteng, Samuel Korsah, Miriam Tagoe, N. N. Nortey, Jessica Korsah, Benedicta Delase Wobetsey, F. Owusu
Background: Cholera affects several hundred thousand individuals worldwide each year. According to estimates, more than 20 million individuals in Ghana are at danger of contracting the illness. However, research from Asia and other continents continues to be a major source of information for understanding cholera epidemiology in Africa, particularly in its coastal nations. The purpose of the study was to evaluate Ghana's cholera epidemics each year. Methods: A thorough analysis of articles that have been published on cholera outbreaks worldwide and in Ghana. A thorough search was done in the databases of Science Direct, PubMed, and Google Scholar to retrieve and to review research works published on cholera. Results: Findings suggest cholera has been a significant public health issue for Ghana every year since the first case was reported in 1970. Greater Accra is the area with the most cholera cases each year, with Accra being the district with the most cases. Greater Accra alone reported 58.5% of all cholera cases in Ghana from 1998 to 2017. However, the least affected regions in Ghana are the Upper West, Northern, Upper East, and Volta region. The cause of these cholera outbreaks is subpar sanitation and contaminated water. Annual cholera outbreaks occur in Ghana, where more attention is needed. Multiple deaths have been caused by these epidemics. Conclusion: Improved sanitation and provision of adequate clean drinking water can help curb the incidence of cholera and its devastating effects on individuals and the country as a whole.
背景:霍乱每年影响全世界几十万人。据估计,加纳有2000多万人有感染这种疾病的危险。然而,来自亚洲和其他大陆的研究仍然是了解非洲,特别是其沿海国家霍乱流行病学的主要信息来源。这项研究的目的是评估加纳每年的霍乱疫情。方法:对已发表的关于世界各地和加纳霍乱暴发的文章进行彻底分析。在Science Direct、PubMed和Google Scholar的数据库中进行了彻底的搜索,以检索和审查已发表的关于霍乱的研究成果。结果:研究结果表明,自1970年报告首例病例以来,霍乱每年都是加纳的一个重大公共卫生问题。大阿克拉是每年霍乱病例最多的地区,其中阿克拉是病例最多的地区。1998年至2017年,仅大阿克拉就报告了加纳所有霍乱病例的58.5%。然而,加纳受影响最小的地区是上西部、北部、上东部和沃尔特地区。这些霍乱爆发的原因是卫生条件差和水受到污染。加纳每年都发生霍乱疫情,需要给予更多关注。这些流行病已造成多人死亡。结论:改善卫生条件和提供充足的清洁饮用水有助于遏制霍乱的发病率及其对个人和整个国家的破坏性影响。
{"title":"Outbreak of Cholera in Ghana: A Systematic Review from 2010 to 2020","authors":"J. Apenteng, Samuel Korsah, Miriam Tagoe, N. N. Nortey, Jessica Korsah, Benedicta Delase Wobetsey, F. Owusu","doi":"10.9734/ajrid/2023/v13i2261","DOIUrl":"https://doi.org/10.9734/ajrid/2023/v13i2261","url":null,"abstract":"Background: Cholera affects several hundred thousand individuals worldwide each year. According to estimates, more than 20 million individuals in Ghana are at danger of contracting the illness. However, research from Asia and other continents continues to be a major source of information for understanding cholera epidemiology in Africa, particularly in its coastal nations. The purpose of the study was to evaluate Ghana's cholera epidemics each year. \u0000Methods: A thorough analysis of articles that have been published on cholera outbreaks worldwide and in Ghana. A thorough search was done in the databases of Science Direct, PubMed, and Google Scholar to retrieve and to review research works published on cholera. \u0000Results: Findings suggest cholera has been a significant public health issue for Ghana every year since the first case was reported in 1970. Greater Accra is the area with the most cholera cases each year, with Accra being the district with the most cases. Greater Accra alone reported 58.5% of all cholera cases in Ghana from 1998 to 2017. However, the least affected regions in Ghana are the Upper West, Northern, Upper East, and Volta region. The cause of these cholera outbreaks is subpar sanitation and contaminated water. Annual cholera outbreaks occur in Ghana, where more attention is needed. Multiple deaths have been caused by these epidemics. \u0000Conclusion: Improved sanitation and provision of adequate clean drinking water can help curb the incidence of cholera and its devastating effects on individuals and the country as a whole.","PeriodicalId":166387,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114651895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laboratory and Sonographic Assessment of Intestinal Parasitic Load of Peasant Farmers in Emekuku Village in Nigeria 尼日利亚Emekuku村农民肠道寄生虫负荷的实验室和超声评估
Pub Date : 2023-05-05 DOI: 10.9734/ajrid/2023/v13i2260
E. Odumeru, C. Njoku, C. Ewurum, K. Agwunobi
Background: Intestinal parasites (IP) are organisms that live and strife within the host for harm or mutual benefit, is a global concern infecting over 3 billion people and causing morbidity in about 450 million people worldwide of which the developing countries are most affected, the majority being school children, rural dwellers, and peasant farmers. Parasitic load (PL) in our locality has not been assessed, or determined, and comparisons made based on biographic data of the peasant farmers. Objective: The study was aimed at determining the PL of peasant farmers in Emekuku by Laboratory and Sonographic examinations. Methods: A cross-sectional study design with a purposive non-probability sampling technique was used to select 126 subjects within the age group of 20 years to 90 years of both sexes. Stool specimens were collected, Wet preparation and Concentration Methods were used for laboratory investigation and comparisons were made. Sonography was used for the confirmation and characterization of IP. Data were analyzed with simple descriptive statistics and chi-square. Results: Wet prep technique recorded 10 (7.94%) positive cases while the Concentration method recorded 44 (34.92%) positive cases (P < 0.05). Ascaris lumbricoides amongst other IPs had the highest manifestation in the study, most prevalent in the age group 80 to 89 years,10 (62.5%) and more occurring in the female 10 (15.87%) and significant (P =0.039967). Sonographic indices for confirmation of IP were 4 (80.0%) out of 5. Conclusion: Sonography complements the role of Laboratory stool analysis for the presence, characterization, location, and complications of IP such as Ascaris lumbricoides.
背景:肠道寄生虫(IP)是一种生活在宿主体内并为伤害或互惠而斗争的生物,是一个全球关注的问题,感染了30多亿人,并在全世界约4.5亿人中造成发病率,其中发展中国家受影响最严重,大多数是学童、农村居民和农民。寄生负荷(PL)在我们的地方尚未评估,或确定,并根据农民的传记数据进行比较。目的:采用实验室检查和超声检查相结合的方法对埃马库库地区农民的肾上腺素含量进行测定。方法:采用有目的的非概率抽样方法,采用横断面研究设计,选取年龄在20 ~ 90岁的男女共126例。采集粪便标本,采用湿法制和浓缩法进行实验室调查和比较。超声检查用于确认和表征IP。数据分析采用简单描述性统计和卡方分析。结果:湿法阳性10例(7.94%),浓缩法阳性44例(34.92%)(P < 0.05);其中,类蚓蛔虫的发病率最高,以80 ~ 89岁年龄组发生率最高,占62.5%,女性发生率最高,占15.87%,差异有统计学意义(P =0.039967)。5个声像图指标中,有4个(80.0%)能确认IP。结论:超声检查补充了实验室粪便分析的作用,对IP的存在、特征、位置和并发症,如蚓状蛔虫。
{"title":"Laboratory and Sonographic Assessment of Intestinal Parasitic Load of Peasant Farmers in Emekuku Village in Nigeria","authors":"E. Odumeru, C. Njoku, C. Ewurum, K. Agwunobi","doi":"10.9734/ajrid/2023/v13i2260","DOIUrl":"https://doi.org/10.9734/ajrid/2023/v13i2260","url":null,"abstract":"Background: Intestinal parasites (IP) are organisms that live and strife within the host for harm or mutual benefit, is a global concern infecting over 3 billion people and causing morbidity in about 450 million people worldwide of which the developing countries are most affected, the majority being school children, rural dwellers, and peasant farmers. Parasitic load (PL) in our locality has not been assessed, or determined, and comparisons made based on biographic data of the peasant farmers. \u0000Objective: The study was aimed at determining the PL of peasant farmers in Emekuku by Laboratory and Sonographic examinations. \u0000Methods: A cross-sectional study design with a purposive non-probability sampling technique was used to select 126 subjects within the age group of 20 years to 90 years of both sexes. Stool specimens were collected, Wet preparation and Concentration Methods were used for laboratory investigation and comparisons were made. Sonography was used for the confirmation and characterization of IP. Data were analyzed with simple descriptive statistics and chi-square. \u0000Results: Wet prep technique recorded 10 (7.94%) positive cases while the Concentration method recorded 44 (34.92%) positive cases (P < 0.05). Ascaris lumbricoides amongst other IPs had the highest manifestation in the study, most prevalent in the age group 80 to 89 years,10 (62.5%) and more occurring in the female 10 (15.87%) and significant (P =0.039967). Sonographic indices for confirmation of IP were 4 (80.0%) out of 5. \u0000Conclusion: Sonography complements the role of Laboratory stool analysis for the presence, characterization, location, and complications of IP such as Ascaris lumbricoides.","PeriodicalId":166387,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122205404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Influencing the Utilization of Insecticide Treated Bed Nets in the Prevention of Malaria in the Berekum East Municipality, Ghana 影响在加纳东Berekum市使用经杀虫剂处理的蚊帐预防疟疾的因素
Pub Date : 2023-05-04 DOI: 10.9734/ajrid/2023/v13i2259
Philip Gyaase, Emmanuel Boateng Acheampong, D. Sampson, R. Owusu
Introduction: The goal of the study was to assess the factors that influence the utilization of Insecticide Treated bed Nets (ITN) in the prevention of malaria in the Berekum East Municipality.  Methods: Quantitative cross sectional design was used to conduct the study in the Berekum East Municipality. Total of 307 respondents aged between 20-60 years were randomly selected for data collection with the aid of a questionnaire. Data were analysed with Statistical Package for the Social Sciences (SPSS) version 23.0. Descriptive and logistic regression analyses were used to examine the factors influencing ITN use at 95% confidence interval. Results: The study found that 87.6% of the respondents owned ITN; however 28% of them used it regularly while 72% use it irregularly. Only 12.4% of the respondents did not use ITN because they did not have them. Majority of the respondents (94.4%) had sufficient knowledge about INT. The reasons that prevented the people from using the ITN included inconvenienced sleeping under them, skin rashes and heat intolerance. The key predictors of appropriate use of ITN were education level, the number of occupants per room, the structure of the room and the knowledge level and the availability of ITNs. Age range 20-30 year had odds ratio of 1.633 of using ITN than other age groups. Likewise, people with tertiary education had OR 2.036 ITN usage more than other educational categories. Conclusion: There was high ITN ownership with poor usage. Strengthening health education of the benefits and importance of ITN use will improve appropriate utilization of ITN among the people of Berekum Municipality.
前言:本研究的目的是评估影响东别列库姆市使用经杀虫剂处理的蚊帐预防疟疾的因素。方法:采用定量横断面设计方法在东别列库姆市进行研究。随机抽取年龄在20-60岁之间的307人,采用问卷调查的方式进行数据收集。数据分析采用社会科学统计软件包(SPSS) 23.0版本。采用描述性和逻辑回归分析在95%置信区间内检验影响ITN使用的因素。结果:研究发现87.6%的受访者拥有ITN;然而,其中28%的人经常使用手机,而72%的人不经常使用手机。只有12.4%的受访者没有使用ITN,因为他们没有ITN。大多数受访者(94.4%)对INT有足够的了解。人们不使用ITN的原因包括睡觉不方便、皮疹和不耐热。适当使用ITN的关键预测因素是教育水平、每个房间的居住者人数、房间的结构以及ITN的知识水平和可用性。20 ~ 30岁年龄组使用ITN的比值比为1.633。同样,受过高等教育的人使用ITN的比率为2.036,高于其他教育类别的人。结论:ITN拥有率高,但使用率低。加强关于使用蚊帐的好处和重要性的健康教育,将改善别列库姆市人民对蚊帐的适当利用。
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引用次数: 0
Awareness of Zoonotic Diseases among the Bachelor of Science New Entrants at the Open University of Sri Lanka in 2020 2020年斯里兰卡开放大学理科学士新生对人畜共患疾病的认识
Pub Date : 2023-04-29 DOI: 10.9734/ajrid/2023/v13i1257
Vidyani S. Kulatunga, Shehani Fernando, U. Jayawardena, C. Jayasinghe
Global attention towards zoonotic diseases has been oriented with the emergence of the COVID-19 pandemic in 2020 as they are infectious diseases that can be transmitted from animals to humans, and they pose a significant threat to public health. This study draws on the awareness of a group of new BSc degree registrants (N=267) at The Open University of Sri Lanka in 2020 about common zoonotic diseases. A cross-sectional study was employed for the participants in a virtual orientation session in December 2020 using a structured online questionnaire. Pearson Chi-square test (χ2) was used evaualte statistical significance at p<0.05. The survey reveals that from the total respondents, 89.9% were aware of zoonotic diseases in humans by animals, 77.9% are aware that zoonotic diseases can be transmitted to humans by direct contact with infected animals and 75.3% knew that zoonotic diseases can be transmitted by eating raw meat of infected animals. Further, 82.4% and 86.1% of respondents agreed that zoonotic diseases could be treated and prevented while 85.4% agreed that zoonotic diseases could be controlled. The majority of the respondents were aware of Rabies, Covid 19, Malaria, Dengue fever and SARS as zoonotic diseases and a higher proportion of female respondents identified Hepatitis E as a zoonotic disease. Bovine tuberculosis was identified by students who studied biological sciences compared to other streams. Respondents below 24 years of age identified Anthrax and Leptospirosis, SARS and Trichinellosis as zoonotic diseases than other age categories. Students in suburban areas had a higher tendency to identify Ebola virus disease, Giardiasis, and Hepatitis E as zoonotic diseases. Urban and suburban students had a higher tendency to wash their hands thoroughly after petting the animals. Pet owners only identified Giardiasis as a zoonotic disease and agreed that avoiding direct contact with animals, avoidance of rearing pets indoors and discarding pet faeces in a proper place as good practices to avoid the transmission of zoonoses. Most of the respondents agreed that zoonotic diseases could be prevented by avoiding eating raw meat, avoiding eating unwashed fresh fruits and vegetables, avoiding direct contact with animals, avoiding rearing pets indoors, regular vaccination of pets, proper discharge of animal faeces, washing the hands thoroughly after petting the animals. Overall, this study revealed that the level of awareness about zoonotic diseases among the new BSc registrants was satisfactory. It is inferred that the students could be more educated about the preventive and control measures for zoonotic diseases. It is expected that students will develop essential life skills that are required for the prevention and control of diseases.
随着2020年COVID-19大流行的出现,全球对人畜共患疾病的关注已经转向,因为它们是可以从动物传播给人类的传染病,对公共卫生构成重大威胁。本研究利用了2020年斯里兰卡开放大学一组新学士学位注册人(N=267)对常见人畜共患疾病的认识。在2020年12月的一次虚拟培训会上,对参与者进行了一项横断面研究,使用了结构化的在线问卷。采用Pearson卡方检验(χ2)评价差异有统计学意义,p<0.05。调查显示,在所有受访者中,89.9%的人知道动物感染人的人畜共患疾病,77.9%的人知道人畜共患疾病可通过直接接触感染动物传染给人,75.3%的人知道人畜共患疾病可通过食用感染动物的生肉传染。82.4%和86.1%的受访者认为人畜共患疾病可以治疗和预防,85.4%的受访者认为人畜共患疾病可以控制。大多数受访者知道狂犬病、Covid - 19、疟疾、登革热和SARS是人畜共患疾病,女性受访者认为戊型肝炎是人畜共患疾病的比例较高。与其他学科相比,研究生物科学的学生发现了牛结核病。24岁以下的应答者认为炭疽和钩端螺旋体病、非典型肺炎和旋毛虫病是人畜共患疾病。郊区学生将埃博拉病毒病、贾第虫病和戊型肝炎识别为人畜共患疾病的倾向较高。城市和郊区的学生更倾向于在抚摸动物后彻底洗手。宠物主人只认为贾第虫病是一种人畜共患疾病,并同意避免与动物直接接触、避免在室内饲养宠物和将宠物粪便丢弃在适当的地方是避免人畜共患疾病传播的良好做法。大多数受访者认为,预防人畜共患疾病的措施包括:避免食用生肉、避免食用未经清洗的新鲜水果和蔬菜、避免与动物直接接触、避免在室内饲养宠物、定期为宠物接种疫苗、适当排放动物粪便、抚摸动物后彻底洗手。总的来说,这项研究表明,新登记的人对人畜共患疾病的认识水平是令人满意的。由此推测,可以对学生进行有关人畜共患疾病预防和控制措施的教育。预期学生将发展预防和控制疾病所需的基本生活技能。
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引用次数: 0
The Impact of COVID on Microbiology Examination Result with its Further analysis based on Student’s gender and Place of Residence COVID对微生物学检查结果的影响及其基于学生性别和居住地的进一步分析
Pub Date : 2023-04-29 DOI: 10.9734/ajrid/2023/v13i1258
L. S. Sunarti, E. S. Arodes, Yusias Hikmat Diani, Ayu Aulia Salshabila
Aims: To study the impact of COVID on Microbiology examination result, and analyze it further based on the gender and place of residence. Methods: Simple analysis conducted cross-sectionally based on the comparison of the result of final Microbiology exam result based on the student’s gender and place of residence. Data classified by the class of 2018 (Pre-COVID), 2019 (initial COVID) and 2020 (prolonged COVID). Results: There is a pattern of decreasing exam scores, both in theory and practicum, when compared to exam results before COVID (class of 2018), during the initial of the COVID pandemic (class of 2019)   and 1 year after COVID became a pandemic but not yet fully controlled (class of 2020). Conclusion: COVID caused direct impact to medical education, in our context to Microbiology examination result.
目的:研究COVID对微生物学检查结果的影响,并根据性别和居住地进一步分析。方法:根据学生性别和居住地对期末微生物学考试结果进行对比,进行简单的横断面分析。按2018年(预冠)、2019年(初始冠)和2020年(延长冠)分类的数据。结果:与COVID之前(2018级)、COVID大流行初期(2019级)和COVID成为大流行但尚未完全控制的一年后(2020级)的考试成绩相比,理论和实践考试成绩都出现了下降的模式。结论:新冠肺炎疫情对医学教育造成直接影响,在我们的背景下对微生物学考试成绩造成影响。
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引用次数: 0
Should we Relax the Norms on SARS CoV-2 Pandemic Yet?: Analysis of the Joint Statement on COVID Pandemic within India 我们是否应该放松对SARS - CoV-2大流行的规范?:对印度国内新冠肺炎疫情联合声明的分析
Pub Date : 2023-04-21 DOI: 10.9734/ajrid/2023/v13i1256
Ria Roy, Sarita Kumari, K. Naveen
The demographic and genomics of COVID-19 have changed with the advent of new BF.7 and XBB Omicron variants in the population. IPHA and IAPSM have released the 5th Joint statement on COVID-19 pandemic in India, where “Living with COVID” is the main theme. The report has summarized that it was time to declare an end to the pandemic, and institutionalize mechanisms for preventing misuse of any emergent disease. However, we should look towards the trends worldwide and be prepared for incoming new variants with robust surveillance to prevent another pandemic. Genomic sequencing and its association with the disease severity, strengthening the comprehensive primary health services are few of the measures that can be taken. Evidence-based decisions should be followed rather than keeping only restrained allocation of resources in mind. Despite the present endemic status of COVID-19, state level recommendations and mandates of masks, sanitisers or social distancing might apply in case there is rise of cases. With passage of time, protection against reinfection decreased regardless of vaccination before or after infection. However, people who were both infected and vaccinated had higher protection than those who were uninfected, or received a second dose of vaccine after the same time had elapsed. Remaining cautious and encouraging vaccination for the population should be our ongoing strategy for maintaining high level of seropositivity in the population.
随着人群中新的BF.7和XBB组粒变异的出现,COVID-19的人口统计学和基因组学发生了变化。IPHA和IAPSM发布了关于印度COVID-19大流行的第五次联合声明,其中“与COVID共存”是主题。该报告总结说,现在是时候宣布结束这一流行病,并将防止滥用任何新出现疾病的机制制度化。然而,我们应该展望全球趋势,并为即将到来的新变种做好准备,并进行强有力的监测,以防止另一次大流行。基因组测序及其与疾病严重程度的关系、加强综合初级保健服务是可以采取的少数措施。应遵循循证决策,而不是只考虑有限的资源分配。尽管目前COVID-19处于流行状态,但如果病例增加,州一级的建议和要求可能适用口罩、消毒剂或保持社交距离。随着时间的推移,无论是在感染前还是在感染后接种疫苗,对再次感染的保护作用都在下降。然而,既感染又接种疫苗的人比未感染或在同一时间后接种第二剂疫苗的人具有更高的保护作用。保持谨慎和鼓励人群接种疫苗应该是我们维持人群高水平血清阳性的持续战略。
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引用次数: 0
期刊
Asian Journal of Research in Infectious Diseases
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