首页 > 最新文献

Journal of Orofacial Sciences最新文献

英文 中文
Remineralizing Agents in the Prevention of Caries: A Systematic Review and Meta-analysis of Randomized Controlled Trials 再矿化剂预防龋齿:随机对照试验的系统回顾和荟萃分析
Q3 Dentistry Pub Date : 2021-07-01 DOI: 10.4103/jofs.jofs_235_21
D. Vasamsetti, Srinivas Pachava, Devaki Talluri
Introduction: The systematic review presented here aims to determine and find out the clinical efficacy of various remineralization agents for early enamel caries. Materials and methods: An aggregate of 240 articles has been retrieved from PubMed, Cochrane Library, Trip, and Google scholarly databases from 2010 to 2020, of which 18 randomized controlled trials (RCTs) have been integrated into this systematic review, and six of which were considered for meta-analysis. The risk of bias in each study was evaluated using the Cochrane collaboration’s tool. Results: Ten of the 18 studies suggest that carious lesions are successfully minimized by remineralization. Four studies showed superior efficacy of casein phosphopeptide and amorphous calcium phosphate (CPP-ACP) in the remineralization of white spot lesions. There was no statistically significant difference (standard mean difference = −0.18, 95% confidence interval: −0.48 to 0.12, P = 0.23) between the experimental and control groups. Conclusion: This review has demonstrated an absence of dependable proof supporting the clinical adequacy of remineralizing agents. Therefore, RCTs in well-designed forms are needed to enhance all sorts of evidence in this field.
前言:本系统综述旨在确定和了解各种再矿化剂治疗早期牙釉质龋的临床疗效。材料和方法:从PubMed、Cochrane Library、Trip和谷歌学术数据库中检索到2010年至2020年的240篇文章,其中18篇随机对照试验(rct)被纳入本系统综述,其中6篇被纳入meta分析。每项研究的偏倚风险使用Cochrane协作工具进行评估。结果:18项研究中有10项表明,再矿化可以成功地减少龋齿病变。四项研究显示酪蛋白磷酸肽和无定形磷酸钙(CPP-ACP)对白斑病变再矿化有较好的疗效。实验组与对照组间差异无统计学意义(标准均值差= - 0.18,95%可信区间:- 0.48 ~ 0.12,P = 0.23)。结论:本综述显示缺乏可靠的证据支持再矿化药物的临床充分性。因此,需要设计良好的随机对照试验来增强该领域的各种证据。
{"title":"Remineralizing Agents in the Prevention of Caries: A Systematic Review and Meta-analysis of Randomized Controlled Trials","authors":"D. Vasamsetti, Srinivas Pachava, Devaki Talluri","doi":"10.4103/jofs.jofs_235_21","DOIUrl":"https://doi.org/10.4103/jofs.jofs_235_21","url":null,"abstract":"Introduction: The systematic review presented here aims to determine and find out the clinical efficacy of various remineralization agents for early enamel caries. Materials and methods: An aggregate of 240 articles has been retrieved from PubMed, Cochrane Library, Trip, and Google scholarly databases from 2010 to 2020, of which 18 randomized controlled trials (RCTs) have been integrated into this systematic review, and six of which were considered for meta-analysis. The risk of bias in each study was evaluated using the Cochrane collaboration’s tool. Results: Ten of the 18 studies suggest that carious lesions are successfully minimized by remineralization. Four studies showed superior efficacy of casein phosphopeptide and amorphous calcium phosphate (CPP-ACP) in the remineralization of white spot lesions. There was no statistically significant difference (standard mean difference = −0.18, 95% confidence interval: −0.48 to 0.12, P = 0.23) between the experimental and control groups. Conclusion: This review has demonstrated an absence of dependable proof supporting the clinical adequacy of remineralizing agents. Therefore, RCTs in well-designed forms are needed to enhance all sorts of evidence in this field.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":"13 1","pages":"121 - 128"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42887370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Collagen Birefringence in Oral Reactive Lesions Using Picrosirius Red Stain Under Polarized Light Microscopy: An Observational Microscopic Study 应用Picrosius红染色在偏振光显微镜下评价口腔反应性病变中的胶原双折射:一项观察显微镜研究
Q3 Dentistry Pub Date : 2021-01-01 DOI: 10.4103/jofs.jofs_84_21
A. Shirona, U. Hegde, H. Sreeshyla
Introduction: Oral reactive lesions are relatively common. Collagen is the basic component of such overgrowths that could be fibrous or inflammatory. Hence, understanding the type, nature, and distribution of collagen fibers can aid in our knowledge and better management of these lesions. Materials and Methods: Ten paraffin blocks of each of the following lesions − giant-cell granuloma (L1), inflammatory fibrous hyperplasia (L2), pyogenic granuloma (L3), fibroma (L4), and peripheral ossifying fibroma (L5) − were retrieved from the archives. They were analyzed for their collagen birefringence property under polarized microscopy after picrosirius red stain. The demographic details of all the cases were recorded and evaluated. Results: In our study, giant-cell granulomas were commonly observed between third and seventh decades of life, inflammatory fibrous hyperplasias between second and fifth decades of life, yogenic granulomas in sixth decade, fibromas in fifth and sixth decades, and peripheral ossifying fibromas in second and fourth decade of life. All the lesions were predominant in females and commonly observed on gingiva. L5 lesions showed more areas of green birefringence followed by L1, L2, and L3 groups of lesions showed more of red birefringence than other lesions. Mixed birefringence of orange-red and green-yellow was almost same in all the lesions. All these findings were significant statistically. Conclusion: A plausible conclusion that the lesions with mature red fibers have better prognosis than the lesions with immature green fibers, in reactive oral lesions could be drawn.
引言:口腔反应性病变比较常见。胶原蛋白是这种过度生长的基本成分,可能是纤维状或炎症性的。因此,了解胶原纤维的类型、性质和分布有助于我们了解和更好地管理这些病变。材料和方法:从档案中检索以下各病变的10个石蜡块——巨细胞肉芽肿(L1)、炎性纤维增生(L2)、化脓性肉芽肿(L3)、纤维瘤(L4)和周围骨化纤维瘤(L5)。在毕赤染色后,在偏光显微镜下分析它们的胶原双折射特性。记录并评估了所有病例的人口统计细节。结果:在我们的研究中,巨细胞肉芽肿常见于生命的第三至第七十年,炎性纤维增生常见于生命第二至第五十年,酸奶性肉芽肿常见于第六十年,纤维瘤常见于第五至第六年,周围骨化纤维瘤常见在生命第二和第四年。所有病变均以女性为主,常见于牙龈。L5病变显示出更多的绿色双折射区域,其次是L1、L2和L3组病变显示出比其他病变更多的红色双折射。橙红色和绿黄色的混合双折射在所有病变中几乎相同。所有这些发现都具有统计学意义。结论:在反应性口腔病变中,成熟红纤维病变的预后优于未成熟绿纤维病变。
{"title":"Evaluation of Collagen Birefringence in Oral Reactive Lesions Using Picrosirius Red Stain Under Polarized Light Microscopy: An Observational Microscopic Study","authors":"A. Shirona, U. Hegde, H. Sreeshyla","doi":"10.4103/jofs.jofs_84_21","DOIUrl":"https://doi.org/10.4103/jofs.jofs_84_21","url":null,"abstract":"Introduction: Oral reactive lesions are relatively common. Collagen is the basic component of such overgrowths that could be fibrous or inflammatory. Hence, understanding the type, nature, and distribution of collagen fibers can aid in our knowledge and better management of these lesions. Materials and Methods: Ten paraffin blocks of each of the following lesions − giant-cell granuloma (L1), inflammatory fibrous hyperplasia (L2), pyogenic granuloma (L3), fibroma (L4), and peripheral ossifying fibroma (L5) − were retrieved from the archives. They were analyzed for their collagen birefringence property under polarized microscopy after picrosirius red stain. The demographic details of all the cases were recorded and evaluated. Results: In our study, giant-cell granulomas were commonly observed between third and seventh decades of life, inflammatory fibrous hyperplasias between second and fifth decades of life, yogenic granulomas in sixth decade, fibromas in fifth and sixth decades, and peripheral ossifying fibromas in second and fourth decade of life. All the lesions were predominant in females and commonly observed on gingiva. L5 lesions showed more areas of green birefringence followed by L1, L2, and L3 groups of lesions showed more of red birefringence than other lesions. Mixed birefringence of orange-red and green-yellow was almost same in all the lesions. All these findings were significant statistically. Conclusion: A plausible conclusion that the lesions with mature red fibers have better prognosis than the lesions with immature green fibers, in reactive oral lesions could be drawn.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":"13 1","pages":"47 - 53"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45682209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HPV-16 Detection and Quantitation in Whole Mouth Fluid of Oral and Cervical Cancer Patients 癌症患者全口液中HPV-16的检测与定量
Q3 Dentistry Pub Date : 2021-01-01 DOI: 10.4103/jofs.jofs_38_21
Bose Divya, U. Rao, R. Thavarajah, E. Joshua, K. Ranganathan
Introduction: The association of human papillomavirus (HPV) in cervical and oropharyngeal cancer is well established. There is a growing evidence that HPV could possibly contribute to oral cancer along with alcohol and tobacco use. The aim of this study was to evaluate and quantify HPV-16 in the whole mouth fluid of patients with oral squamous cell carcinoma (OSCC), cervical cancer, and normal controls. Materials and Methods: The whole mouth fluid of 20 patients with OSCC (Group I), 10 with cervical cancer (Group II), and 10 normal individuals (Group III) was collected by the spit technique. The DNA was extracted and quantified by quantitative polymerase chain reaction. Data were analyzed by SPSS 21 (IBM Corp. Released 2012, Armonk, NY: IBM Corp) software and analysis of variance test was used. Results: The mean age of Group I patients was 50.9 ± 13.5 years, Group II was 51.6 ± 8.07 years, and Group III was 46 ± 8.5 years. In Group I, 15 were males and 5 were females. In Group III, 5 were males and 5 were females. Eight patients belonging to Group I, four of Group II, and seven of Group III had HPV-16 in their whole mouth fluid. Conclusion: HPV-16 was identified in the whole mouth fluid of OSCC, patients with cervical cancer, and even in normal controls. However, the mean viral loads were highest in patients with cervical cancer followed by patients with OSCC and normal controls.
引言:人乳头瘤病毒(HPV)与子宫颈癌和口咽癌的关系已经得到了很好的证实。越来越多的证据表明,HPV可能会与酒精和烟草的使用一起导致口腔癌。本研究的目的是评估和量化口腔鳞状细胞癌(OSCC)、宫颈癌和正常对照患者全口腔液中的HPV-16。材料与方法:采用唾液法采集20例OSCC患者(ⅰ组)、10例宫颈癌患者(ⅱ组)和10例正常人(ⅲ组)的全口液。提取DNA,用定量聚合酶链反应定量。数据分析采用SPSS 21 (IBM Corp. release 2012, Armonk, NY: IBM Corp)软件,采用方差分析检验。结果:ⅰ组患者平均年龄50.9±13.5岁,ⅱ组患者平均年龄51.6±8.07岁,ⅲ组患者平均年龄46±8.5岁。第一组雄性15只,雌性5只。第三组男性5只,女性5只。ⅰ组8例,ⅱ组4例,ⅲ组7例,全口液中有HPV-16。结论:HPV-16在OSCC患者、宫颈癌患者及正常对照组的全口液中均有检出。然而,宫颈癌患者的平均病毒载量最高,其次是OSCC患者和正常对照。
{"title":"HPV-16 Detection and Quantitation in Whole Mouth Fluid of Oral and Cervical Cancer Patients","authors":"Bose Divya, U. Rao, R. Thavarajah, E. Joshua, K. Ranganathan","doi":"10.4103/jofs.jofs_38_21","DOIUrl":"https://doi.org/10.4103/jofs.jofs_38_21","url":null,"abstract":"Introduction: The association of human papillomavirus (HPV) in cervical and oropharyngeal cancer is well established. There is a growing evidence that HPV could possibly contribute to oral cancer along with alcohol and tobacco use. The aim of this study was to evaluate and quantify HPV-16 in the whole mouth fluid of patients with oral squamous cell carcinoma (OSCC), cervical cancer, and normal controls. Materials and Methods: The whole mouth fluid of 20 patients with OSCC (Group I), 10 with cervical cancer (Group II), and 10 normal individuals (Group III) was collected by the spit technique. The DNA was extracted and quantified by quantitative polymerase chain reaction. Data were analyzed by SPSS 21 (IBM Corp. Released 2012, Armonk, NY: IBM Corp) software and analysis of variance test was used. Results: The mean age of Group I patients was 50.9 ± 13.5 years, Group II was 51.6 ± 8.07 years, and Group III was 46 ± 8.5 years. In Group I, 15 were males and 5 were females. In Group III, 5 were males and 5 were females. Eight patients belonging to Group I, four of Group II, and seven of Group III had HPV-16 in their whole mouth fluid. Conclusion: HPV-16 was identified in the whole mouth fluid of OSCC, patients with cervical cancer, and even in normal controls. However, the mean viral loads were highest in patients with cervical cancer followed by patients with OSCC and normal controls.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":"13 1","pages":"8 - 12"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42285789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Myogenous Temporomandibular Joint Disorders on Cervical Range of Motion: A Prospective Study 肌源性颞下颌关节紊乱对颈椎活动范围的影响:一项前瞻性研究
Q3 Dentistry Pub Date : 2021-01-01 DOI: 10.4103/jofs.jofs_158_19
J. Ahmed, Mandovi Nath, N. Sujir, N. Shenoy, R. Ongole, Almas Binnal
Introduction: Temporomandibular joint disorders (TMDs) involve abnormalities of either the disc or associated muscular structure. Evidence continues to accumulate regarding the untreated diseases of stomatognathic system, in particular, malocclusion and TMDs, which eventually carry a risk of development of postural disorders. The present study was undertaken to assess the correlation between TMDs and altered cervical range of motion and to review its association with the myogenous causes of TMD. Materials and Methods: A total of 80 patients were recruited and were divided into two groups; those diagnosed with TMDs were classified as cases and those who did not suffer from TMDs and/or cervical spine anomalies were classified as controls. Patients reporting with a positive history of painful joints and muscles were examined and were later referred to the department of physiotherapy, where the cervical range of motion was assessed using Baseline® bubble inclinometer. Cervical range of motion in healthy patients was compared with those affected with TMDs using posthoc Tukey test. Results: There was a significant difference in the values for range of motion and was found to be considerably restricted among the TMD subjects. Disability for the range of motion was statistically significant with a P-value of <0.001 for tests of active flexion, passive flexion, left active flexion, and left passive flexion in patients with myogenous TMDs. Conclusion: TMDs were found to be a significant factor in the occurrence of an impaired cervical range of motion.
引言:颞下颌关节疾病(TMDs)涉及椎间盘或相关肌肉结构的异常。关于未经治疗的口腔颌面系统疾病,特别是错牙合和TMDs的证据不断积累,这些疾病最终有发展为姿势障碍的风险。本研究旨在评估TMDs与颈椎活动范围改变之间的相关性,并回顾其与TMD的肌源性原因的关系。材料和方法:共招募80名患者,分为两组;那些被诊断为TMDs的患者被归类为病例,那些没有患有TMDs和/或颈椎异常的患者被分类为对照组。报告有关节和肌肉疼痛阳性病史的患者接受了检查,随后被转诊至理疗科,在那里使用Baseline®气泡测斜仪评估颈部活动范围。健康患者和TMDs患者的颈椎活动范围采用术后Tukey试验进行比较。结果:TMD受试者的运动范围值存在显著差异,并且在很大程度上受到限制。肌源性TMDs患者的主动屈曲、被动屈曲、左主动屈曲和左被动屈曲测试中,运动范围的残疾具有统计学意义,P值<0.001。结论:TMDs是导致颈椎活动范围受损的重要因素。
{"title":"Effect of Myogenous Temporomandibular Joint Disorders on Cervical Range of Motion: A Prospective Study","authors":"J. Ahmed, Mandovi Nath, N. Sujir, N. Shenoy, R. Ongole, Almas Binnal","doi":"10.4103/jofs.jofs_158_19","DOIUrl":"https://doi.org/10.4103/jofs.jofs_158_19","url":null,"abstract":"Introduction: Temporomandibular joint disorders (TMDs) involve abnormalities of either the disc or associated muscular structure. Evidence continues to accumulate regarding the untreated diseases of stomatognathic system, in particular, malocclusion and TMDs, which eventually carry a risk of development of postural disorders. The present study was undertaken to assess the correlation between TMDs and altered cervical range of motion and to review its association with the myogenous causes of TMD. Materials and Methods: A total of 80 patients were recruited and were divided into two groups; those diagnosed with TMDs were classified as cases and those who did not suffer from TMDs and/or cervical spine anomalies were classified as controls. Patients reporting with a positive history of painful joints and muscles were examined and were later referred to the department of physiotherapy, where the cervical range of motion was assessed using Baseline® bubble inclinometer. Cervical range of motion in healthy patients was compared with those affected with TMDs using posthoc Tukey test. Results: There was a significant difference in the values for range of motion and was found to be considerably restricted among the TMD subjects. Disability for the range of motion was statistically significant with a P-value of <0.001 for tests of active flexion, passive flexion, left active flexion, and left passive flexion in patients with myogenous TMDs. Conclusion: TMDs were found to be a significant factor in the occurrence of an impaired cervical range of motion.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":"13 1","pages":"33 - 38"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42473571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tooth Morphometry and Pattern of Palatal Rugae Among Monozygotic Twins in Malaysia 马来西亚同卵双胞胎的牙齿形态测量和腭嵴模式
Q3 Dentistry Pub Date : 2021-01-01 DOI: 10.4103/jofs.jofs_124_21
W. Lestari, N. Adanan, N. Mokhtar, Y. Ardini, S. Ichwan, M. Haris
Introduction: Monozygotic (MZ) twins share the same DNA, placenta, amniotic fluid, and physical features. Genetic factors play a prominent role compared to environmental factors in one’s physical appearance, including dental morphology. Here we studied variation in MZ twin’s tooth morphometry and palatal rugae pattern. Materials and methods: Variation between twins can be a valuable tool in forensics to identify individuals. Ten pairs of MZ twins were selected for this research. The maximum coronal mesiodistal and buccopalatal dimension of the maxillary teeth, excluding the second and third molars, were measured in triplicate using calipers. Palatal rugae patterns of the samples were cast, analyzed, and recorded based on shape and unification. Results: Our results showed a significant tooth dimension correlation between MZ twins. Maxillary central incisors had the least genetic variability, but the Carabelli trait, skeletal pattern, occlusion, and occlusal features all exhibited a greater correlation in MZ twins. Our findings provide compelling evidence for mirroring of dental features and palatal rugae patterns in MZ twins. This study is the first of its kind reported in Malaysia. Conclusion: Marked similarities in tooth morphometry and other dental physical features were observed between twins, which can be a useful tool in forensics for the identification of individuals.
简介:同卵双胞胎拥有相同的DNA、胎盘、羊水和身体特征。与环境因素相比,遗传因素在一个人的外表(包括牙齿形态)中发挥着重要作用。在这里,我们研究了MZ双胞胎牙齿形态计量学和腭嵴模式的变化。材料和方法:双胞胎之间的变异可能是鉴定个体的法医学中一个有价值的工具。本研究选取了10对MZ双胞胎。使用卡尺一式三份测量上颌牙齿(不包括第二和第三磨牙)的最大冠近中、颊阔尺寸。根据形状和统一性,对样品的腭皱图案进行铸造、分析和记录。结果:我们的结果显示MZ双胞胎之间的牙齿尺寸存在显著相关性。上颌中切牙的遗传变异性最小,但在MZ双胞胎中,Carabelli特征、骨骼模式、咬合和咬合特征都表现出更大的相关性。我们的发现为MZ双胞胎的牙齿特征和腭嵴模式提供了令人信服的证据。这是马来西亚首次报道此类研究。结论:双胞胎在牙齿形态计量学和其他牙齿物理特征方面有显著的相似性,这可以作为鉴定个体的法医学工具。
{"title":"Tooth Morphometry and Pattern of Palatal Rugae Among Monozygotic Twins in Malaysia","authors":"W. Lestari, N. Adanan, N. Mokhtar, Y. Ardini, S. Ichwan, M. Haris","doi":"10.4103/jofs.jofs_124_21","DOIUrl":"https://doi.org/10.4103/jofs.jofs_124_21","url":null,"abstract":"Introduction: Monozygotic (MZ) twins share the same DNA, placenta, amniotic fluid, and physical features. Genetic factors play a prominent role compared to environmental factors in one’s physical appearance, including dental morphology. Here we studied variation in MZ twin’s tooth morphometry and palatal rugae pattern. Materials and methods: Variation between twins can be a valuable tool in forensics to identify individuals. Ten pairs of MZ twins were selected for this research. The maximum coronal mesiodistal and buccopalatal dimension of the maxillary teeth, excluding the second and third molars, were measured in triplicate using calipers. Palatal rugae patterns of the samples were cast, analyzed, and recorded based on shape and unification. Results: Our results showed a significant tooth dimension correlation between MZ twins. Maxillary central incisors had the least genetic variability, but the Carabelli trait, skeletal pattern, occlusion, and occlusal features all exhibited a greater correlation in MZ twins. Our findings provide compelling evidence for mirroring of dental features and palatal rugae patterns in MZ twins. This study is the first of its kind reported in Malaysia. Conclusion: Marked similarities in tooth morphometry and other dental physical features were observed between twins, which can be a useful tool in forensics for the identification of individuals.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":"13 1","pages":"39 - 46"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46607822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cytotoxicity of Silorane and Methacrylate based Dental Composites on Human Pulp Cells 硅烷和甲基丙烯酸酯基牙科复合材料对人牙髓细胞的细胞毒性
Q3 Dentistry Pub Date : 2021-01-01 DOI: 10.4103/jofs.jofs_312_20
Prashanthi Madhyastha, K. Bhat, D. Padma, M. Bangera, Dilip G Naik, N. Srikant, R. Kotian
Introduction: The ingredients from the dental restoratives are known to leach and elicit a host response. The prerequisite to deem a material biocompatible requires its toxicologic evaluation. The study was performed to analyze the probable toxicity resulting from silorane-based composite (SBC) with methacrylate-based composite (MBC). Materials and Methods: The in vitro cytotoxicity test, methyl thiazolyl tetrazolium (MTT) assay, evaluated the cell viability and proliferation rate of dental pulp cells (DPCs). The extirpated pulp was cultured in α-MEM-containing supplements and incubated at 37°C. DPCs were subjected to varying doses of SBC or MBC at different time intervals after attaining confluence and monitored for proliferation and viability via MTT assay. An independent Student t test was performed to compare the effect of composites on the DPC. The cytotoxicity levels were compared using one-way analysis of variance and posthoc Tukey multiple comparison test at 5% level of significance and P-value of <0.05. Results: DPC exposed to MBC showed higher viability than SBC. The MTT assay reported the number of viable cells as (>90%) in the first 24 hours. The count significantly reduced by the end of 48 hours (minimum 65% in 25 μg/ml) at all concentrations (P < 0.05). SBC had lower survival than MBC in all concentrations and periods. Except at 5 μg/ml concentration at 48 hours in SBC, no statistically significant values were reported. Conclusion: DPCs are prone to the cytotoxicity caused by dental composite. In contrast to MBC, the cytotoxicity of SBC declines overtime.
引言:众所周知,牙科修复剂中的成分会浸出并引发宿主反应。认为材料具有生物相容性的先决条件是对其进行毒理学评估。本研究旨在分析硅烷基复合材料(SBC)与甲基丙烯酸酯基复合材料的可能毒性。材料与方法:采用体外细胞毒性试验-甲基噻唑四氮唑(MTT)法,评价牙髓细胞(DPCs)的细胞活力和增殖率。摘除的果肉在含有α-MEM的补充剂中培养,并在37°C下孵育。DPC在达到汇合后的不同时间间隔接受不同剂量的SBC或MBC,并通过MTT测定监测增殖和活力。进行了一项独立的Student t测试,以比较复合材料对DPC的影响。使用单向方差分析和死后Tukey多重比较试验在前24小时内比较细胞毒性水平(显著性水平为5%,P值为90%)。到48小时结束时,计数显著减少(25小时内至少减少65% μg/ml)(P<0.05)。SBC在所有浓度和时间段的存活率均低于MBC。5点除外 在SBC中48小时的浓度为μg/ml时,没有统计显著值的报告。结论:DPCs易产生由牙科复合材料引起的细胞毒性。与MBC相比,SBC的细胞毒性随着时间的推移而下降。
{"title":"Cytotoxicity of Silorane and Methacrylate based Dental Composites on Human Pulp Cells","authors":"Prashanthi Madhyastha, K. Bhat, D. Padma, M. Bangera, Dilip G Naik, N. Srikant, R. Kotian","doi":"10.4103/jofs.jofs_312_20","DOIUrl":"https://doi.org/10.4103/jofs.jofs_312_20","url":null,"abstract":"Introduction: The ingredients from the dental restoratives are known to leach and elicit a host response. The prerequisite to deem a material biocompatible requires its toxicologic evaluation. The study was performed to analyze the probable toxicity resulting from silorane-based composite (SBC) with methacrylate-based composite (MBC). Materials and Methods: The in vitro cytotoxicity test, methyl thiazolyl tetrazolium (MTT) assay, evaluated the cell viability and proliferation rate of dental pulp cells (DPCs). The extirpated pulp was cultured in α-MEM-containing supplements and incubated at 37°C. DPCs were subjected to varying doses of SBC or MBC at different time intervals after attaining confluence and monitored for proliferation and viability via MTT assay. An independent Student t test was performed to compare the effect of composites on the DPC. The cytotoxicity levels were compared using one-way analysis of variance and posthoc Tukey multiple comparison test at 5% level of significance and P-value of <0.05. Results: DPC exposed to MBC showed higher viability than SBC. The MTT assay reported the number of viable cells as (>90%) in the first 24 hours. The count significantly reduced by the end of 48 hours (minimum 65% in 25 μg/ml) at all concentrations (P < 0.05). SBC had lower survival than MBC in all concentrations and periods. Except at 5 μg/ml concentration at 48 hours in SBC, no statistically significant values were reported. Conclusion: DPCs are prone to the cytotoxicity caused by dental composite. In contrast to MBC, the cytotoxicity of SBC declines overtime.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":"13 1","pages":"13 - 18"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44096457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparison of Condylar Bone Density in Cone-Beam Computed Tomographic Images of Patients with and without Temporomandibular Joint Disorders 有与无颞下颌关节疾病患者锥形束ct图像中髁突骨密度的比较
Q3 Dentistry Pub Date : 2021-01-01 DOI: 10.4103/jofs.jofs_89_21
Maryam Eisazadeh, L. Khojastepour, Abdolaziz Haghnegahdar, P. Soltani
Introduction: Temporomandibular disorders (TMDs) are the main source of orofacial pain of nondental origin. Density changes in mandibular condyles of patients with TMD have not been well documented. The aim of this study was to compare condylar head bone density values in patient with and without TMD in cone-beam computed tomographic (CBCT) images. Materials and Methods: CBCT images of 70 patients with TMD and 70 age- and sex-controlled individuals were studied. Density of the cancellous bone in the left and right condylar heads was measured on a CBCT slice with the widest mediolateral dimension. Moreover, absence of at least one maxillary or mandibular posterior tooth (except for third molars) was recorded. Interclass correlation, t test, and Chi-squared test were used for statistical analysis. Results: Bone density in the condylar head significantly increased in patients with TMD compared with the non-TMD group (P < 0.001). The difference between males and females in each group was not significant (P = 0.182). Condylar head bone density in patients with TMD with posterior missing teeth was significantly less than individuals without missing teeth (P = 0.002). Conclusion: Increased density of condylar head must be regarded as a potential diagnostic tool for TMD when interpreting CBCT images of the joints.
引言:颞下颌关节紊乱病(TMDs)是非牙源性口面疼痛的主要来源。TMD患者下颌髁突的密度变化尚未得到充分的记录。本研究的目的是比较锥形束计算机断层扫描(CBCT)图像中患有和不患有TMD的患者的髁突骨密度值。材料和方法:对70例TMD患者和70例年龄和性别对照者的CBCT图像进行研究。在CBCT切片上测量左右髁头部松质骨的密度,该切片具有最宽的中外侧尺寸。此外,记录到至少一颗上颌或下颌后牙缺失(第三磨牙除外)。采用类间相关、t检验和卡方检验进行统计分析。结果:TMD患者髁突骨密度较非TMD组明显增高(P<0.001),各组间差异无统计学意义(P = 有后牙缺失的TMD患者的髁骨密度显著低于无缺失的患者(P = 0.002)。结论:在解释关节CBCT图像时,髁突头密度的增加必须被视为TMD的潜在诊断工具。
{"title":"Comparison of Condylar Bone Density in Cone-Beam Computed Tomographic Images of Patients with and without Temporomandibular Joint Disorders","authors":"Maryam Eisazadeh, L. Khojastepour, Abdolaziz Haghnegahdar, P. Soltani","doi":"10.4103/jofs.jofs_89_21","DOIUrl":"https://doi.org/10.4103/jofs.jofs_89_21","url":null,"abstract":"Introduction: Temporomandibular disorders (TMDs) are the main source of orofacial pain of nondental origin. Density changes in mandibular condyles of patients with TMD have not been well documented. The aim of this study was to compare condylar head bone density values in patient with and without TMD in cone-beam computed tomographic (CBCT) images. Materials and Methods: CBCT images of 70 patients with TMD and 70 age- and sex-controlled individuals were studied. Density of the cancellous bone in the left and right condylar heads was measured on a CBCT slice with the widest mediolateral dimension. Moreover, absence of at least one maxillary or mandibular posterior tooth (except for third molars) was recorded. Interclass correlation, t test, and Chi-squared test were used for statistical analysis. Results: Bone density in the condylar head significantly increased in patients with TMD compared with the non-TMD group (P < 0.001). The difference between males and females in each group was not significant (P = 0.182). Condylar head bone density in patients with TMD with posterior missing teeth was significantly less than individuals without missing teeth (P = 0.002). Conclusion: Increased density of condylar head must be regarded as a potential diagnostic tool for TMD when interpreting CBCT images of the joints.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":"13 1","pages":"3 - 7"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45110151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparative Analysis between Linear Measures from Bidimensional and Three-dimensional Images of the Face for Human Identification Purpose: A Pilot Study 用于人类识别目的的二维和三维人脸图像线性度量的比较分析:一项初步研究
Q3 Dentistry Pub Date : 2021-01-01 DOI: 10.4103/jofs.jofs_289_20
P. Pinto, V. Jacometti, J. Pereira, Marco Silva, R. Silva
Introduction: Photo-anthropometry is a method of facial image comparison that consists of taking measurements on images. The objective of this study was to verify if facial measurements obtained from a two-dimensional (2D) image can be applied for the purpose of human identification when compared with measurements obtained from a three-dimensional (3D) image. Materials and Methods: In this cross-sectional research, a convenience sample was formed by 3D and 2D images of 12 participants. In these images, 35 linear measurements were taken between landmarks. The 2D images were obtained in different angles and norms (left and right sides, and front sides), and the measures were categorized into vertical, lateral, and lip regions. The data were organized in Excel® spreadsheets (Microsoft Corp., Redmond, Washington, USA) and submitted to descriptive statistics. Results: The vertical measurements in lateral norms were more divergent than the measurements of 3D images, whereas the measurements of the lip region showed less differences in all norms. In the lateral norms, vertical measures such as nasion–pogonion were underestimated by 14.35 mm, whereas this same measure was overestimated by 7.20 mm in the frontal norm. In the lip region, the most underestimated measures were crista philtri (left)–cheilion (left) at 5.95 mm and crista philtri (right)–cheilion (right) at 5.45 mm, and the most overestimated was cheilion (right)–cheilion (left) at 4.38 mm, all in the frontal norm. Conclusion: The facial measurements obtained in 2D images can be underestimated or overestimated depending on the angle and norm of each image.
简介:照片人体测量是一种面部图像比较方法,包括对图像进行测量。本研究的目的是验证与从三维(3D)图像获得的测量结果相比,从二维(2D)图像中获得的面部测量结果是否可以用于人类识别。材料和方法:在这项横断面研究中,12名参与者的3D和2D图像形成了一个方便的样本。在这些图像中,在地标之间进行了35次线性测量。2D图像是在不同的角度和规范(左侧、右侧和前侧)下获得的,测量分为垂直、横向和唇部区域。数据被组织在Excel®电子表格中(微软公司,美国华盛顿州雷德蒙德),并提交给描述性统计数据。结果:侧模的垂直测量结果比3D图像的测量结果更具差异性,而唇部的测量结果在所有规范中的差异较小。在侧位规范中,鼻骨-前角等垂直测量被低估了14.35 毫米,而同样的测量值被高估了7.20 mm。在嘴唇区域,最被低估的测量值是嵴(左)-cheilion(左),为5.95 mm和腓嵴(右)-cheilion(右)5.45 mm,而被高估最多的是cheilion(右)–cheilion 毫米,都在正面标准。结论:根据每张图像的角度和范数,在2D图像中获得的面部测量可能被低估或高估。
{"title":"Comparative Analysis between Linear Measures from Bidimensional and Three-dimensional Images of the Face for Human Identification Purpose: A Pilot Study","authors":"P. Pinto, V. Jacometti, J. Pereira, Marco Silva, R. Silva","doi":"10.4103/jofs.jofs_289_20","DOIUrl":"https://doi.org/10.4103/jofs.jofs_289_20","url":null,"abstract":"Introduction: Photo-anthropometry is a method of facial image comparison that consists of taking measurements on images. The objective of this study was to verify if facial measurements obtained from a two-dimensional (2D) image can be applied for the purpose of human identification when compared with measurements obtained from a three-dimensional (3D) image. Materials and Methods: In this cross-sectional research, a convenience sample was formed by 3D and 2D images of 12 participants. In these images, 35 linear measurements were taken between landmarks. The 2D images were obtained in different angles and norms (left and right sides, and front sides), and the measures were categorized into vertical, lateral, and lip regions. The data were organized in Excel® spreadsheets (Microsoft Corp., Redmond, Washington, USA) and submitted to descriptive statistics. Results: The vertical measurements in lateral norms were more divergent than the measurements of 3D images, whereas the measurements of the lip region showed less differences in all norms. In the lateral norms, vertical measures such as nasion–pogonion were underestimated by 14.35 mm, whereas this same measure was overestimated by 7.20 mm in the frontal norm. In the lip region, the most underestimated measures were crista philtri (left)–cheilion (left) at 5.95 mm and crista philtri (right)–cheilion (right) at 5.45 mm, and the most overestimated was cheilion (right)–cheilion (left) at 4.38 mm, all in the frontal norm. Conclusion: The facial measurements obtained in 2D images can be underestimated or overestimated depending on the angle and norm of each image.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":"13 1","pages":"19 - 27"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46846248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social Accountability of Research Publications in Journals 期刊研究出版物的社会责任
Q3 Dentistry Pub Date : 2021-01-01 DOI: 10.4103/jofs.jofs_58_21
A. B. Rajendra
The aim of all journals is to publish high-quality evidence-based research. The research mainly focuses on scientific impact on fields and professions. Thus, a journal is an indicator of scientific advancement in the society, in academia, and in professionals, and should be able to connect with the common man. As journals continue to publish, they need to demonstrate greater alignment with being socially accountable .
所有期刊的目标都是发表高质量的循证研究。该研究主要关注科学对领域和专业的影响。因此,期刊是社会、学术界和专业领域科学进步的一个指标,应该能够与普通人联系起来。随着期刊的继续出版,它们需要表现出更大的社会责任感。
{"title":"Social Accountability of Research Publications in Journals","authors":"A. B. Rajendra","doi":"10.4103/jofs.jofs_58_21","DOIUrl":"https://doi.org/10.4103/jofs.jofs_58_21","url":null,"abstract":"The aim of all journals is to publish high-quality evidence-based research. The research mainly focuses on scientific impact on fields and professions. Thus, a journal is an indicator of scientific advancement in the society, in academia, and in professionals, and should be able to connect with the common man. As journals continue to publish, they need to demonstrate greater alignment with being socially accountable .","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":"13 1","pages":"1 - 2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43925665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tobacco Related Oral Lesions in South Indian Industrial Workers 南印度产业工人与烟草有关的口腔病变
Q3 Dentistry Pub Date : 2021-01-01 DOI: 10.4103/jofs.jofs_24_21
R. Kommalapati, A. B. Rajendra, K. Kattappagari, L. Kantheti, Chandrashekar Poosarla, V. Baddam
Introduction: Tobacco is the leading causative factor for both oral potentially malignant disorders and oral cancer. Tobacco use is higher among lower income population. Low-income population of India are majorly employed as industrial workers. The aim of this study is to estimate the prevalence of oral lesions associated with tobacco related habits among industrial workers. Materials and Methods: Cross-sectional epidemiological investigation was conducted among 1000 industrial workers using simple random sampling technique. Information on patient demographics, tobacco related (smoke and smokeless) and other deleterious habits, and clinical examination details were recorded in a structured format. The data were analyzed using Statistical Package for Social Sciences version 20.0. Results were tabulated using frequency distribution and mean with a standard deviation. Multiple logistical regression was used to analyze oral lesions by different variables. Results: Among the 1000 industrial workers screened, smoking habit was observed in 13.20%, while 86.8% were using smokeless tobacco. The prevalence of tobacco related oral lesions among individuals with smoke/smokeless tobacco habit was 13.8%. The study documented tobacco related oral lesions such as leukoplakia (6.5%), oral submucous fibrosis (2%), smoker’s palate (2.7%), tobacco related pigmentation (1.9%), erythroplakia (0.3%), and oral squamous cell carcinoma (0.2%). Conclusion: The study documented potentially malignant disorders and oral cancer among users with tobacco related habits. The results also revealed that higher prevalence of potentially malignant disorders over oral cancer. Thus, preventive programs for early detection of oral precancer and oral cancer such as tobacco cessation, tobacco counselling programs are emphasized for industrial workers.
烟草是口腔潜在恶性疾病和口腔癌的主要致病因素。烟草使用在低收入人群中较高。印度的低收入人口主要是产业工人。本研究的目的是估计工业工人中与烟草相关习惯相关的口腔病变的患病率。资料与方法:采用简单随机抽样方法,对1000名产业工人进行横断面流行病学调查。以结构化格式记录患者人口统计信息、烟草相关(吸烟和无烟)和其他有害习惯以及临床检查细节。使用Statistical Package for Social Sciences version 20.0对数据进行分析。结果采用频率分布和标准差均值制表。采用多元逻辑回归对不同变量的口腔病变进行分析。结果:筛查的1000名产业工人中,有吸烟习惯的占13.20%,使用无烟烟草的占86.8%。吸烟/无烟吸烟人群中烟草相关口腔病变患病率为13.8%。该研究记录了烟草相关的口腔病变,如白斑(6.5%)、口腔黏膜下纤维化(2%)、吸烟者的上颚(2.7%)、烟草相关的色素沉着(1.9%)、红斑病(0.3%)和口腔鳞状细胞癌(0.2%)。结论:该研究记录了吸烟相关习惯使用者中潜在的恶性疾病和口腔癌。结果还显示,潜在恶性疾病的患病率高于口腔癌。因此,早期发现口腔癌前病变和口腔癌的预防方案,如戒烟,烟草咨询方案,被强调为产业工人。
{"title":"Tobacco Related Oral Lesions in South Indian Industrial Workers","authors":"R. Kommalapati, A. B. Rajendra, K. Kattappagari, L. Kantheti, Chandrashekar Poosarla, V. Baddam","doi":"10.4103/jofs.jofs_24_21","DOIUrl":"https://doi.org/10.4103/jofs.jofs_24_21","url":null,"abstract":"Introduction: Tobacco is the leading causative factor for both oral potentially malignant disorders and oral cancer. Tobacco use is higher among lower income population. Low-income population of India are majorly employed as industrial workers. The aim of this study is to estimate the prevalence of oral lesions associated with tobacco related habits among industrial workers. Materials and Methods: Cross-sectional epidemiological investigation was conducted among 1000 industrial workers using simple random sampling technique. Information on patient demographics, tobacco related (smoke and smokeless) and other deleterious habits, and clinical examination details were recorded in a structured format. The data were analyzed using Statistical Package for Social Sciences version 20.0. Results were tabulated using frequency distribution and mean with a standard deviation. Multiple logistical regression was used to analyze oral lesions by different variables. Results: Among the 1000 industrial workers screened, smoking habit was observed in 13.20%, while 86.8% were using smokeless tobacco. The prevalence of tobacco related oral lesions among individuals with smoke/smokeless tobacco habit was 13.8%. The study documented tobacco related oral lesions such as leukoplakia (6.5%), oral submucous fibrosis (2%), smoker’s palate (2.7%), tobacco related pigmentation (1.9%), erythroplakia (0.3%), and oral squamous cell carcinoma (0.2%). Conclusion: The study documented potentially malignant disorders and oral cancer among users with tobacco related habits. The results also revealed that higher prevalence of potentially malignant disorders over oral cancer. Thus, preventive programs for early detection of oral precancer and oral cancer such as tobacco cessation, tobacco counselling programs are emphasized for industrial workers.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":"13 1","pages":"28 - 32"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47842436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Journal of Orofacial Sciences
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1