Background: Management of haemodynamic among women with post-partum hemorrhage after caesarean section. Objective: The purpose of the present study was to compare the effect of carbetocin and oxytocin on haemodynamic among women with post-partum hemorrhage after caesarean section. Methodology: This randomized controlled trial was conducted in the Department of Obstetrics and Gynaecology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2015 to December 2015 for a period of six months. Pregnant women diagnosed on the standard criteria admitted in BSMMU, Dhaka, Bangladesh were selected as study population by consecutive type of sampling. Randomization was performed according to computer generated simple random sampling method. An Uterotonic was an agent used to induce contraction or greater tonicity of the uterus. Then the patients were monitored per operatively and post operatively. All the information was recorded in data collection sheet. Main outcome variables were estimated blood loss. Results: A total number of 96 pregnant women were recruited for this s tudy of which 48 cases were enrolled in group I and the rest of 48 case were enrolled in group II. The mean age with SD of the group I and group II were 24.4±4.7 years and 24.7±3.7 years (p=0.729). Before administration of drug, mean systolic blood pressure was found 115.6±5.8 mmHg in group I and 114.8±7.8 mmHg in group II. At 24 hours after caesarean section, mean systolic blood pressure was found 116.9±5.8 mmHg in group I and 113.9±8.8 mmHg in group II (p>0.05). Before administration of drug, mean diastolic blood pressure was found 75.8±7.9 mmHg in group I and 76.9±9.9 mmHg in group II. At 24 hours after caesarean section, mean diastolic blood pressure was found 76.7±6.6 mmHg in group I and 76.1±7.2 mmHg in group II (p>0.05). Before administration of drug, mean maternal blood loss was found 376.4±110.4 ml in group I and 439.4±199.9 ml in group II. At 24 hours after caesarean section, mean maternal blood loss was found 468.2±121.9 ml in group I and 532.6±243.0 ml in group II (p>0.05). Conclusion: In conclusion the systolic blood pressure, diastolic blood pressure and blood loss are not significantly varied in group I and II. Journal of National Institute of Neurosciences Bangladesh, July 2023;9(2):141-146
{"title":"Effects of Carbetocin and Oxytocin on Haemodynamic among Women with Post-Partum Hemorrhage after Caesarean Section: A Single Blind Parallel Arm Randomized Controlled Trial","authors":"Farhana Haque Choudhury, Shahnaz Ahmed, Syeda Tania Tanzin, Silvia Rahman, Naheed Fatema, K. Khatun","doi":"10.3329/jninb.v9i2.70884","DOIUrl":"https://doi.org/10.3329/jninb.v9i2.70884","url":null,"abstract":"Background: Management of haemodynamic among women with post-partum hemorrhage after caesarean section.\u0000Objective: The purpose of the present study was to compare the effect of carbetocin and oxytocin on haemodynamic among women with post-partum hemorrhage after caesarean section.\u0000Methodology: This randomized controlled trial was conducted in the Department of Obstetrics and Gynaecology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2015 to December 2015 for a period of six months. Pregnant women diagnosed on the standard criteria admitted in BSMMU, Dhaka, Bangladesh were selected as study population by consecutive type of sampling. Randomization was performed according to computer generated simple random sampling method. An Uterotonic was an agent used to induce contraction or greater tonicity of the uterus. Then the patients were monitored per operatively and post operatively. All the information was recorded in data collection sheet. Main outcome variables were estimated blood loss.\u0000Results: A total number of 96 pregnant women were recruited for this s tudy of which 48 cases were enrolled in group I and the rest of 48 case were enrolled in group II. The mean age with SD of the group I and group II were 24.4±4.7 years and 24.7±3.7 years (p=0.729). Before administration of drug, mean systolic blood pressure was found 115.6±5.8 mmHg in group I and 114.8±7.8 mmHg in group II. At 24 hours after caesarean section, mean systolic blood pressure was found 116.9±5.8 mmHg in group I and 113.9±8.8 mmHg in group II (p>0.05). Before administration of drug, mean diastolic blood pressure was found 75.8±7.9 mmHg in group I and 76.9±9.9 mmHg in group II. At 24 hours after caesarean section, mean diastolic blood pressure was found 76.7±6.6 mmHg in group I and 76.1±7.2 mmHg in group II (p>0.05). Before administration of drug, mean maternal blood loss was found 376.4±110.4 ml in group I and 439.4±199.9 ml in group II. At 24 hours after caesarean section, mean maternal blood loss was found 468.2±121.9 ml in group I and 532.6±243.0 ml in group II (p>0.05).\u0000Conclusion: In conclusion the systolic blood pressure, diastolic blood pressure and blood loss are not significantly varied in group I and II.\u0000Journal of National Institute of Neurosciences Bangladesh, July 2023;9(2):141-146","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"49 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140733457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-07DOI: 10.3329/jninb.v9i2.65381
Nazmul Kabir, K. Ahmed, Md Sadekur Rahman Sarker, Md Tauhidul Islam Chowdhury
Background: Stroke and IHD is a major health problem all over the world. But few studies have been done in our country to see the association of IHD among ischaemic stroke patients. Objective: The purpose of the present study was to evaluate the prevalence of IHD among hospitalized ischaemic stroke patients and to identify their common risk factors. Methodology: This was a cross-sectional study carried out in 50 ischaemic stroke patients admitted in Medicine Wards of Khulna Medical College Hospital, from July 2012 to December 2012. The patients were taken in both sexes having more than 18 years age and CT-scan evidence of ischaemic stroke by purposive sampling technique. After recruitment of patients IHD was established by ECG findings. Subsequently other risk factors were identified and were recorded. Results: The incidence of stroke for individuals older than 80 years was approximately 30.0% compared with 8.0% for individuals between 31 to 40 years of age. Among them IHD was more common in 51 to 60 years old stroke patients (33.33%) but less common in older than 80 years of age (8.33%). All of those having both ischaemic stroke and IHD were hypertensive. Among them 58.33% cases had severe hypertension but those having only stroke but no IHD 73.68% cases were hypertensive. Among them 34.21% had severe hypertension. Regarding lipid profile those having both ischaemic stroke and IHD 83.33% were dyslipidaemic but of those having only stroke but no IHD 52.63% were dyslipidaemic. This study revealed 41.67% diabetic patients developed both Ischaemic stroke and IHD compared to 31.58% diabetic patients developed only ischaemic stroke. Conclusion: In conclusion IHD and ischaemic stroke patients share similar pathophysiological mechanisms and, consequently, many risk factors. Journal of National Institute of Neurosciences Bangladesh, July 2023; 9(2):98-102
{"title":"Association of Ischaemic Heart Disease with Hospitalized Ischaemic Stroke Patients in a Tertiary Care Hospital","authors":"Nazmul Kabir, K. Ahmed, Md Sadekur Rahman Sarker, Md Tauhidul Islam Chowdhury","doi":"10.3329/jninb.v9i2.65381","DOIUrl":"https://doi.org/10.3329/jninb.v9i2.65381","url":null,"abstract":"Background: Stroke and IHD is a major health problem all over the world. But few studies have been done in our country to see the association of IHD among ischaemic stroke patients. Objective: The purpose of the present study was to evaluate the prevalence of IHD among hospitalized ischaemic stroke patients and to identify their common risk factors. Methodology: This was a cross-sectional study carried out in 50 ischaemic stroke patients admitted in Medicine Wards of Khulna Medical College Hospital, from July 2012 to December 2012. The patients were taken in both sexes having more than 18 years age and CT-scan evidence of ischaemic stroke by purposive sampling technique. After recruitment of patients IHD was established by ECG findings. Subsequently other risk factors were identified and were recorded. Results: The incidence of stroke for individuals older than 80 years was approximately 30.0% compared with 8.0% for individuals between 31 to 40 years of age. Among them IHD was more common in 51 to 60 years old stroke patients (33.33%) but less common in older than 80 years of age (8.33%). All of those having both ischaemic stroke and IHD were hypertensive. Among them 58.33% cases had severe hypertension but those having only stroke but no IHD 73.68% cases were hypertensive. Among them 34.21% had severe hypertension. Regarding lipid profile those having both ischaemic stroke and IHD 83.33% were dyslipidaemic but of those having only stroke but no IHD 52.63% were dyslipidaemic. This study revealed 41.67% diabetic patients developed both Ischaemic stroke and IHD compared to 31.58% diabetic patients developed only ischaemic stroke. Conclusion: In conclusion IHD and ischaemic stroke patients share similar pathophysiological mechanisms and, consequently, many risk factors. \u0000Journal of National Institute of Neurosciences Bangladesh, July 2023; 9(2):98-102","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"15 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140732572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Angiographic severity of coronary artery is essential to correlate with serum uric acid among acute coronary syndrome patients. Objective: The purpose of the present study was to correlate the Friesinger Score of angiographic severity of coronary artery with or without hyperuricaemia among acute coronary syndrome patients. Methodology: This cross-sectional study was carried out in the Department of Cardiology at National Institute of Cardiovascular Diseases, Dhaka, Bangladesh during the period of December 2011 to November 2012. Patients who were newly diagnosed as acute coronary syndrome during admission undergoing coronary angiography in National Institute of Cardiovascular Diseases, Dhaka during the specified period of time were the study population. Coronary angiography was done within 4 weeks after hospital admission. Study subjects were divided into two groups on the basis of serum uric acid levels. Patients who were newly diagnosed as acute coronary syndrome having normal serum uric acid levels (<7 mg/dl in men & <6 mg/dl in women) were included in group I. Patients who were newly diagnosed as acute coronary syndrome having elevated serum uric acid levels (>7 mg/dl in men & >6mg/dl in women) were included in group II. Results: A total number of 103 patients were recruited for this study who were divided into two groups and 53 patients having normal serum uric acid were considered in group I and 50 patients having hyperuricaemia acid were considered in group II. The mean age of study subjects among group I and group II are 50.45±10.33 years and 52.98±10.559 years respectively. The value of stenosis in Friesinger score in group II (9.30±3.955) was remarkably higher than that of group I (3.77±3.43) and it was statistically highly significant (p=0.001). Here, the vessel score is also markedly higher in group II (2.14±0.83) than that of group-I (0.77±0.75) (p=0.001). The Pearson's correlation coefficient (r) was 0.288 which was significant (p< 0.037). Conclusion: In conclusion it showed that there was a positive linear correlation between Friesinger scores and normal level of serum uric acid. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):60-64
{"title":"Correlation of Friesinger Score of Angiographic Severity of Coronary Artery with or without Hyperuricaemia among Acute Coronary Syndrome Patients","authors":"Newaz Mohsin Ismail Yousuf, Khandaker Qamrul Islam, Mir Jamal Uddin, Md Akhtaruzzaman, Romena Rahman, Qazi Hena Ferdousi","doi":"10.3329/jninb.v9i1.65264","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65264","url":null,"abstract":"Background: Angiographic severity of coronary artery is essential to correlate with serum uric acid among acute coronary syndrome patients. Objective: The purpose of the present study was to correlate the Friesinger Score of angiographic severity of coronary artery with or without hyperuricaemia among acute coronary syndrome patients. Methodology: This cross-sectional study was carried out in the Department of Cardiology at National Institute of Cardiovascular Diseases, Dhaka, Bangladesh during the period of December 2011 to November 2012. Patients who were newly diagnosed as acute coronary syndrome during admission undergoing coronary angiography in National Institute of Cardiovascular Diseases, Dhaka during the specified period of time were the study population. Coronary angiography was done within 4 weeks after hospital admission. Study subjects were divided into two groups on the basis of serum uric acid levels. Patients who were newly diagnosed as acute coronary syndrome having normal serum uric acid levels (<7 mg/dl in men & <6 mg/dl in women) were included in group I. Patients who were newly diagnosed as acute coronary syndrome having elevated serum uric acid levels (>7 mg/dl in men & >6mg/dl in women) were included in group II. Results: A total number of 103 patients were recruited for this study who were divided into two groups and 53 patients having normal serum uric acid were considered in group I and 50 patients having hyperuricaemia acid were considered in group II. The mean age of study subjects among group I and group II are 50.45±10.33 years and 52.98±10.559 years respectively. The value of stenosis in Friesinger score in group II (9.30±3.955) was remarkably higher than that of group I (3.77±3.43) and it was statistically highly significant (p=0.001). Here, the vessel score is also markedly higher in group II (2.14±0.83) than that of group-I (0.77±0.75) (p=0.001). The Pearson's correlation coefficient (r) was 0.288 which was significant (p< 0.037). Conclusion: In conclusion it showed that there was a positive linear correlation between Friesinger scores and normal level of serum uric acid. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):60-64","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.68170
KM Ahasan Ahmed, Md Tauhidul Islam Chowdhury, Mohammad Sadekur Rahman Sarkar, Md Abdul Alim, Md Abdullah Yusuf, Mohammad Shah Jahirul Hoque Chowdhury, Uttam Kumar Saha, Md Badrul Alam
Background: Ischemic stroke is the most common type of all stroke events. About 2.7 million people die each year from ischemic stroke. Facilities for reperfusion therapy in hyper-acute state is not widely available in our country. Use of neuro-protective agents like citicoline may be considered as a reasonable adjunct with antiplatelet agents. Objective: The objective of this study was to evaluate the safety and efficacy of citicoline in treatment of acute ischemic stroke as a neuro-protective agent. Methodology: This was a randomized controlled trial which was conducted in Neurology Unit of National Institute of Neurosciences & Hospital, Dhaka, Bangladesh from January 2017 to December 2017. Acute ischemic stroke patients presented with National Institute of Health Stroke Scale (NIHSS) ≥ 5 were recruited for this study. The study population were divided into 2 groups designated as study and control groups. Control group received standard treatment of acute ischemic stroke whereas study participants were treated with standard stroke medications along with citicoline. Outcome and adverse events were recorded at one week and at twelve weeks of treatment onset. The primary end points of outcome were assessed using NIHSS and mRS at twelve weeks. NIHSS ≤1 and/or mRS ≤2 were considered as good functional outcome. Results: A total number of 109 acute ischemic stroke patients were recruited for this study of which 53 cases in the study group and 56 cases in the control group. More number of patients achieved good functional outcome (mRS ≤2) in citicoline group in comparison to control group, 62.96% and 37.03% in study and control group respectively (p=0.362), though this difference was not statistically significant. There were no significant changes of biochemical parameters, major and minor adverse events between two groups at 1 week and 12 weeks follow up. A significant number of patients died in control group in comparison of study group, 45.45% vs. 23.8% (p=0.0483) within 12-week period. Conclusion: In this study, functional outcome is found better in citicoline group. Survival benefit is observed with citicoline group in comparison to control which is statistically significant. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):3-10
{"title":"Safety and Efficacy of Citicoline among Acute Ischemic Stroke Bangladeshi Patients: A Randomized Control Trial","authors":"KM Ahasan Ahmed, Md Tauhidul Islam Chowdhury, Mohammad Sadekur Rahman Sarkar, Md Abdul Alim, Md Abdullah Yusuf, Mohammad Shah Jahirul Hoque Chowdhury, Uttam Kumar Saha, Md Badrul Alam","doi":"10.3329/jninb.v9i1.68170","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.68170","url":null,"abstract":"Background: Ischemic stroke is the most common type of all stroke events. About 2.7 million people die each year from ischemic stroke. Facilities for reperfusion therapy in hyper-acute state is not widely available in our country. Use of neuro-protective agents like citicoline may be considered as a reasonable adjunct with antiplatelet agents. Objective: The objective of this study was to evaluate the safety and efficacy of citicoline in treatment of acute ischemic stroke as a neuro-protective agent. Methodology: This was a randomized controlled trial which was conducted in Neurology Unit of National Institute of Neurosciences & Hospital, Dhaka, Bangladesh from January 2017 to December 2017. Acute ischemic stroke patients presented with National Institute of Health Stroke Scale (NIHSS) ≥ 5 were recruited for this study. The study population were divided into 2 groups designated as study and control groups. Control group received standard treatment of acute ischemic stroke whereas study participants were treated with standard stroke medications along with citicoline. Outcome and adverse events were recorded at one week and at twelve weeks of treatment onset. The primary end points of outcome were assessed using NIHSS and mRS at twelve weeks. NIHSS ≤1 and/or mRS ≤2 were considered as good functional outcome. Results: A total number of 109 acute ischemic stroke patients were recruited for this study of which 53 cases in the study group and 56 cases in the control group. More number of patients achieved good functional outcome (mRS ≤2) in citicoline group in comparison to control group, 62.96% and 37.03% in study and control group respectively (p=0.362), though this difference was not statistically significant. There were no significant changes of biochemical parameters, major and minor adverse events between two groups at 1 week and 12 weeks follow up. A significant number of patients died in control group in comparison of study group, 45.45% vs. 23.8% (p=0.0483) within 12-week period. Conclusion: In this study, functional outcome is found better in citicoline group. Survival benefit is observed with citicoline group in comparison to control which is statistically significant. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):3-10","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"228 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.68185
Sudipta Kumer Mukherjee, DM Arman, Abdullah Al Mahbub, SIM Khairun Nabi Khan, Jack Wellington
A spinal epidermoid cyst is a rare congenital tumour that may be associated with spinal dysraphism. Congenital spinal epidermoid cysts without spinal dysraphism are rare. Here we are reporting a rare and interesting case of thoracic Intradural extra-medullary epidermoid cyst not associated with spinal dysraphism. Epidermoid cysts (EC) represent less than 1.0% and are rarely seen as an intradural extra-medullary spinal cord tumor. Preoperative Clinico- Radiological assumption is important for surgical planning. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):88-95
{"title":"Pediatric Dorsal Intradural Extra-Medullary Epidermoid Cyst (Non-Dysraphic): An Illustrative Case with Literature Review","authors":"Sudipta Kumer Mukherjee, DM Arman, Abdullah Al Mahbub, SIM Khairun Nabi Khan, Jack Wellington","doi":"10.3329/jninb.v9i1.68185","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.68185","url":null,"abstract":"A spinal epidermoid cyst is a rare congenital tumour that may be associated with spinal dysraphism. Congenital spinal epidermoid cysts without spinal dysraphism are rare. Here we are reporting a rare and interesting case of thoracic Intradural extra-medullary epidermoid cyst not associated with spinal dysraphism. Epidermoid cysts (EC) represent less than 1.0% and are rarely seen as an intradural extra-medullary spinal cord tumor. Preoperative Clinico- Radiological assumption is important for surgical planning. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):88-95","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The problem of widespread resistant bacteria has become a major threat to reduce the effectiveness of antibiotics worldwide. Objective: The aim of this study was to identify the bacterial pathogens from bold culture and determine their antibiotic susceptibility pattern. Methodology: This cross-sectional study was conducted in the department of Microbiology at Monno Medical College, Manikganj, Bangladesh during the period from January 2019 to December 2019 for duration of one year. Blood was collected according to blood collection guidelines and inoculated into BacT/ALERT FA plus and BacT/ALERT PF plus aerobic blood culture bottles respectively. After collection these bottles were immediately incubated in BacT/ALERT 3D (manufactured by bioMerieoux, France) a fully automated blood culture system. Antimicrobial susceptibility test was done for all isolated bacteria by disc diffusion method. Results: A total number of 180 patients were recruited, among them 12 (7%) yielded growth of different bacteria. The most frequently isolated bacteria were Streptococcus Spp 5(42%) followed by Staphylococcus aureus and Escherichia coli which were 4(33%) and 3(25%) respectively. Escherichia Coli which showed highly sensitive to Imipenum, Amikacin, Linezolid, Gentamicin (N=3, 100%). Conclusion: There were a high percentage of bacteria isolated from blood culture and resistant to several antibiotics. For the selection of appropriate antibiotic therapy in bacterial infections the antibiotic susceptibility testing is mandatory. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):48-53
背景:广泛存在的耐药菌问题已成为降低抗生素有效性的主要威胁。目的:从大胆培养中鉴定病原菌并确定其药敏模式。方法:本横断面研究于2019年1月至2019年12月在孟加拉国Manikganj Monno医学院微生物学系进行，为期一年。按采血指南采血，分别接种于BacT/ALERT FA +和BacT/ALERT PF +有氧血培养瓶中。收集后，这些瓶子立即在BacT/ALERT 3D(法国bioMerieoux公司制造)全自动血液培养系统中孵育。所有分离菌均采用纸片扩散法进行药敏试验。结果:共纳入180例患者，其中12例(7%)产生不同细菌。检出最多的细菌是5型链球菌(42%)，其次是金黄色葡萄球菌(4株)和大肠杆菌(3株)，分别为33%和25%。大肠杆菌对亚胺培南、阿米卡星、利奈唑胺、庆大霉素高度敏感(N= 3,100%)。结论:血培养分离出的细菌对多种抗生素耐药的比例较高。为了在细菌感染中选择合适的抗生素治疗，抗生素敏感性试验是强制性的。孟加拉国国家神经科学研究所杂志，2023年1月;9(1):48-53
{"title":"Bacterial Predominance and Antimicrobial Susceptibility Patterns of Blood Culture at a Tertiary Care Hospital, Bangladesh","authors":"Tarana Jahan, Md Abdullah Yusuf, Khandaker Md Tasnim Sajid, Sharmeen Sultana, Md Mostaqimur Rahman, Afroza Sultana","doi":"10.3329/jninb.v9i1.65403","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65403","url":null,"abstract":"Background: The problem of widespread resistant bacteria has become a major threat to reduce the effectiveness of antibiotics worldwide. Objective: The aim of this study was to identify the bacterial pathogens from bold culture and determine their antibiotic susceptibility pattern. Methodology: This cross-sectional study was conducted in the department of Microbiology at Monno Medical College, Manikganj, Bangladesh during the period from January 2019 to December 2019 for duration of one year. Blood was collected according to blood collection guidelines and inoculated into BacT/ALERT FA plus and BacT/ALERT PF plus aerobic blood culture bottles respectively. After collection these bottles were immediately incubated in BacT/ALERT 3D (manufactured by bioMerieoux, France) a fully automated blood culture system. Antimicrobial susceptibility test was done for all isolated bacteria by disc diffusion method. Results: A total number of 180 patients were recruited, among them 12 (7%) yielded growth of different bacteria. The most frequently isolated bacteria were Streptococcus Spp 5(42%) followed by Staphylococcus aureus and Escherichia coli which were 4(33%) and 3(25%) respectively. Escherichia Coli which showed highly sensitive to Imipenum, Amikacin, Linezolid, Gentamicin (N=3, 100%). Conclusion: There were a high percentage of bacteria isolated from blood culture and resistant to several antibiotics. For the selection of appropriate antibiotic therapy in bacterial infections the antibiotic susceptibility testing is mandatory. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):48-53","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.65058
Amanullah Bin Siddiq
Abstract not available Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):1-2
孟加拉国家神经科学研究所杂志，2023年1月;9(1):1-2
{"title":"Neurocardiology or Cardioneurology: Interplay of Brain-Heart Axis","authors":"Amanullah Bin Siddiq","doi":"10.3329/jninb.v9i1.65058","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65058","url":null,"abstract":"Abstract not available Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):1-2","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Carotid artery disease would be high in patients having coronary artery disease with diabetes mellitus. Objective: The purpose of the present study was to see frequency, pattern and severity of carotid artery disease among patients with IHD and diabetes mellitus. Methodology: This case-control study was conducted in Department of Cardiology, UCC, BSMMU from July, 2007 to June 2009. Total 100 patients were included in this study. Of them 50 patients were coronary artery disease with diabetes mellitus and another 50 patients were coronary artery disease without diabetes mellitus. Both group were underwent coronary and carotid angiography. Coronary artery stenosis is assessed by different scoring system and carotid artery stenosis are categorized as mild (< 50% stenosis) moderate (50-69% stenosis) and critical (>_ 70% stenosis). Moderate and critical stenosis was considered as significant carotid artery disease. Morphological character of the lesion was also assessed. Results: The mean age was found 57.48 years with 6.04 standard deviation (SD) in DM and 55.64 years with 6.34 standard deviation in NDM group and also 56.56 years with 6.49 standard deviation in the whole study population. the indications of CAG were Post MI evaluation, unstable angina, stable angina, chest pain evaluation and positive ETT were 42.0%, 20.0%, 18.0%, 10.0% and 10.0% in DM group and 32.0%, 28.0%, 20.0%, 8.0% and 12.0 in NDM group respectively. LAD was the commonest artery involved (86.0%), followed by RCA (82.0%), LCX (68.0%) and LM (6.0%) in DM study subjects. Among the NDM LAD artery involved (76.0%), followed by RCA (72.0%), LCX (64.0%) and LM (4.0%) in NDM study subjects. Conclusion: In conclusion, patients of coronary artery disease with diabetic mellitus are having higher frequency and severity of Carotid artery disease than non-diabetic coronary artery disease patients. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):30-34
{"title":"Carotid Artery Involvement in Patients Undergoing Coronary Angiography with Diabetes Mellitus","authors":"AKM Mohiuddin Bhuiyan, KAM Mahbub Hasan, Partha Pratim Saha, Sayeda Sadia Fathema, Najmul Huda Biplob, Md Abul Fazal, Mahboob Morshed, Tahmida Firdousi","doi":"10.3329/jninb.v9i1.65446","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65446","url":null,"abstract":"Background: Carotid artery disease would be high in patients having coronary artery disease with diabetes mellitus. Objective: The purpose of the present study was to see frequency, pattern and severity of carotid artery disease among patients with IHD and diabetes mellitus. Methodology: This case-control study was conducted in Department of Cardiology, UCC, BSMMU from July, 2007 to June 2009. Total 100 patients were included in this study. Of them 50 patients were coronary artery disease with diabetes mellitus and another 50 patients were coronary artery disease without diabetes mellitus. Both group were underwent coronary and carotid angiography. Coronary artery stenosis is assessed by different scoring system and carotid artery stenosis are categorized as mild (< 50% stenosis) moderate (50-69% stenosis) and critical (>_ 70% stenosis). Moderate and critical stenosis was considered as significant carotid artery disease. Morphological character of the lesion was also assessed. Results: The mean age was found 57.48 years with 6.04 standard deviation (SD) in DM and 55.64 years with 6.34 standard deviation in NDM group and also 56.56 years with 6.49 standard deviation in the whole study population. the indications of CAG were Post MI evaluation, unstable angina, stable angina, chest pain evaluation and positive ETT were 42.0%, 20.0%, 18.0%, 10.0% and 10.0% in DM group and 32.0%, 28.0%, 20.0%, 8.0% and 12.0 in NDM group respectively. LAD was the commonest artery involved (86.0%), followed by RCA (82.0%), LCX (68.0%) and LM (6.0%) in DM study subjects. Among the NDM LAD artery involved (76.0%), followed by RCA (72.0%), LCX (64.0%) and LM (4.0%) in NDM study subjects. Conclusion: In conclusion, patients of coronary artery disease with diabetic mellitus are having higher frequency and severity of Carotid artery disease than non-diabetic coronary artery disease patients. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):30-34","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.65380
Md Ayub Ali, Shirin Aktar Jahan, AKM Harun Ar Rashid, Mohammad Shah Kamal, Muhammad Amzad Hussain, Abu Mohammad Shahed
Background: Surgical management is very much crucial among the lower limb fracture patients.
Objective: The purpose of the present study was to find out the mode of injury, involvement of bones and post-operative surgical outcomes of patients presented with lower limbs fractures patients.
Methodology: This prospective hospital-based study was conducted in the Department of Orthopaedic and Traumatology at Cox’s Bazar Medical College Hospital, Cox’s bazar, Bangladesh from January 2019 to June 2022 for a period of three and half years. All the patients who were presented with the clinical features of fracture of lower limbs were selected as study population. The patients were managed by conservative or surgical way. The outcomes of both procedures were recorded.
Results: A total number of 370 cases were recruited for this study. The mean age with SD of the study population was 18.2±11.56 years. Among these road traffic accident was the most common mode of injury which was 204(55.0%) cases. Open type of fracture was found in 141(38.0%) cases and the close was found in 229(62.0%) cases. The most common bones involved was the shaft of tibia and fibula which was 159(43.0%) cases. During conservative treatment mal-union was reported in 193(66.8%) cases and the rest of the 96(33.2%) patients had shown the stiffness. Among 81 operated cases majority were recovered which was 70(86.0%) cases. However, death was found in 2(2.0%) cases. Minor and major infection were reported in 6(8.0%) cases and 3(4.0%) cases respectively.
Conclusion: In conclusion the most common mode of injury is road traffic accident with the involvement of shaft of tibia and fibula with majority improvement.
[Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):60-64]
背景:手术治疗对下肢骨折患者至关重要。
目的:了解下肢骨折患者的损伤方式、受累骨及术后手术效果。
方法:这项基于医院的前瞻性研究于2019年1月至2022年6月在孟加拉国考克斯巴扎尔考克斯巴扎尔医学院医院骨科和创伤科进行，为期三年半。选择所有具有下肢骨折临床特征的患者作为研究人群。采用保守或手术治疗。记录两种手术的结果。
结果:本研究共招募了370例患者。研究人群的平均SD年龄为18.2±11.56岁。其中，道路交通事故是最常见的伤害方式，有204例(55.0%)。开放性骨折141例(38.0%)，闭合性骨折229例(62.0%)。最常见的受累骨为胫骨和腓骨干，共159例(43.0%)。保守治疗期间，193例(66.8%)出现骨不愈合，96例(33.2%)出现骨僵硬。81例手术中，70例(86.0%)痊愈，占多数。然而，死亡2例(2.0%)。轻度感染6例(8.0%)，重度感染3例(4.0%);结论:道路交通事故是胫腓骨轴受累最常见的损伤方式，且多数损伤改善。[Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):60-64]
{"title":"Mode of Injury, Involvement of Bones and Post-Operative Surgical Outcomes of Patients presented with Lower Limbs Fractures attended at a Tertiary Care Hospital at Tourist City of Bangladesh","authors":"Md Ayub Ali, Shirin Aktar Jahan, AKM Harun Ar Rashid, Mohammad Shah Kamal, Muhammad Amzad Hussain, Abu Mohammad Shahed","doi":"10.3329/jninb.v9i1.65380","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65380","url":null,"abstract":"Background: Surgical management is very much crucial among the lower limb fracture patients.
 Objective: The purpose of the present study was to find out the mode of injury, involvement of bones and post-operative surgical outcomes of patients presented with lower limbs fractures patients.
 Methodology: This prospective hospital-based study was conducted in the Department of Orthopaedic and Traumatology at Cox’s Bazar Medical College Hospital, Cox’s bazar, Bangladesh from January 2019 to June 2022 for a period of three and half years. All the patients who were presented with the clinical features of fracture of lower limbs were selected as study population. The patients were managed by conservative or surgical way. The outcomes of both procedures were recorded.
 Results: A total number of 370 cases were recruited for this study. The mean age with SD of the study population was 18.2±11.56 years. Among these road traffic accident was the most common mode of injury which was 204(55.0%) cases. Open type of fracture was found in 141(38.0%) cases and the close was found in 229(62.0%) cases. The most common bones involved was the shaft of tibia and fibula which was 159(43.0%) cases. During conservative treatment mal-union was reported in 193(66.8%) cases and the rest of the 96(33.2%) patients had shown the stiffness. Among 81 operated cases majority were recovered which was 70(86.0%) cases. However, death was found in 2(2.0%) cases. Minor and major infection were reported in 6(8.0%) cases and 3(4.0%) cases respectively.
 Conclusion: In conclusion the most common mode of injury is road traffic accident with the involvement of shaft of tibia and fibula with majority improvement.
 [Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):60-64]","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"198 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.65443
Afroza Sultana, M Lutful Kabir, Md Abdullah Yusuf, Tarana Jahan, Asma Khan, Tahmida Firdousi, Shamsun Nahar
Background: Drugs prescription pattern is very important at outpatient department in the tertiary care hospital. Objective: The purpose of the present study was to evaluate the distribution of patients and antibiotic prescribing trends in OPD of a Tertiary Medical College hospital. Methodology: This cross-sectional study was undertaken in the medicine, surgery, gynaecology & obstetrics and paediatrics Out Patient Department of Shaheed Suhrawardy Medical college hospital, Dhaka. The duration of the study period was 5 weeks (25th March, 2017 to 29th April, 2017). The study was designed to obtain information regarding prescribing pattern of drugs by physicians and also to analyze basal information of the prescription. The prescription were observed from the hospital’s OPD and few prescriptions were from each unit. Results: A total 320 prescription were observed from the hospital’s OPD where 80 prescriptions were from each unit. The mean age of the patients was 24.50±14.976 years. The most commonly prescribed antibiotics at medicine OPD was Cephalosporin which was 19(51.4%) cases followed by others antibiotics and azithromycin which was 9(24.3%) cases and 8(21.6%) cases respectively. In surgery OPD, the most commonly used antibiotics were flucloxacillin and cephalosporin which was 66(82.5%) cases and 24(30.0%) cases respectively. In Gynae & obstetrics OPD, the most commonly prescribed antibiotics were quinolones as well as other groups of antibiotics which were 23(46.0%) cases and 27(54.0%) cases respectively. Conclusion: In conclusion most commonly used antibiotic are Cephalosporin, azithromycin and Flucloxacillin in different OPD of the hospital. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):54-58
{"title":"Prescription Pattern of Different Groups of Antibiotics at Out Patient Department of a Tertiary Medical College Hospital in Dhaka City","authors":"Afroza Sultana, M Lutful Kabir, Md Abdullah Yusuf, Tarana Jahan, Asma Khan, Tahmida Firdousi, Shamsun Nahar","doi":"10.3329/jninb.v9i1.65443","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65443","url":null,"abstract":"Background: Drugs prescription pattern is very important at outpatient department in the tertiary care hospital. Objective: The purpose of the present study was to evaluate the distribution of patients and antibiotic prescribing trends in OPD of a Tertiary Medical College hospital. Methodology: This cross-sectional study was undertaken in the medicine, surgery, gynaecology & obstetrics and paediatrics Out Patient Department of Shaheed Suhrawardy Medical college hospital, Dhaka. The duration of the study period was 5 weeks (25th March, 2017 to 29th April, 2017). The study was designed to obtain information regarding prescribing pattern of drugs by physicians and also to analyze basal information of the prescription. The prescription were observed from the hospital’s OPD and few prescriptions were from each unit. Results: A total 320 prescription were observed from the hospital’s OPD where 80 prescriptions were from each unit. The mean age of the patients was 24.50±14.976 years. The most commonly prescribed antibiotics at medicine OPD was Cephalosporin which was 19(51.4%) cases followed by others antibiotics and azithromycin which was 9(24.3%) cases and 8(21.6%) cases respectively. In surgery OPD, the most commonly used antibiotics were flucloxacillin and cephalosporin which was 66(82.5%) cases and 24(30.0%) cases respectively. In Gynae & obstetrics OPD, the most commonly prescribed antibiotics were quinolones as well as other groups of antibiotics which were 23(46.0%) cases and 27(54.0%) cases respectively. Conclusion: In conclusion most commonly used antibiotic are Cephalosporin, azithromycin and Flucloxacillin in different OPD of the hospital. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):54-58","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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