Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.65285
Asma Tasnim Khan, Md Abul Hashem, Muhammed Kamrul Hassan, Mahfuja Jakia, Nayanmani Sarkar, Mohammad Irfan Ullah Sakib, Sharmin Jahan
Background: Platelet-rich plasma (PRP) is a treatment that uses a patient's own blood, processed to concentrate platelets and growth factors, to treat erectile dysfunction (ED). Erectile dysfunction (ED) is a common condition that affects men of all ages and can have a significant impact on quality of life. Platelet rich plasma (PRP) is a newer treatment option that involves injecting a concentrated solution of platelets into the affected area to promote healing and tissue regeneration. Objective: The purpose of the present study was to evaluate the efficacy of platelet-rich plasma (PRP) in treating erectile dysfunction (ED). Methodology: A prospective study was conducted to evaluate the efficacy of platelet-rich plasma (PRP) in treating erectile dysfunction (ED) with a sample of 50 patients in Dhaka, Bangladesh during the period of January 2022 to June 2022. The patients received PRP treatment and the improvement in erectile function was measured through standardized questionnaires and scales. Data were collected predesigned data collection sheet. Results: The average age of the study subjects is 53.70 years. The mean scores of the IIEF-EF domain showed a statistically significant improvement from 18.50 ± 3.60 before the procedure to 20.71 ± 3.71 after 6th months (p = 0.002). Sexual satisfaction also showed a statistically significant improvement, with a mean score increasing from 6.00 ± 0.57 before the procedure to 8.00 ± 0.85 after 6th months (p = 0.016). However, there were no statistically significant changes in the mean scores for orgasmic function and sexual desire (p = 0.113 and p = 0.389, respectively). The mean score for general satisfaction showed a small but statistically significant increase from 5.00 ± 0.29 before the procedure to 5.38 ± 0.24 after the 1st month (p = 0.027). Conclusion: In conclusion platelet-rich plasma (PRP) application provides short-term improvement in erectile function. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):71-75
{"title":"Efficacy of Platelet Rich Plasma in Erectile Dysfunction: A Clinical Trial","authors":"Asma Tasnim Khan, Md Abul Hashem, Muhammed Kamrul Hassan, Mahfuja Jakia, Nayanmani Sarkar, Mohammad Irfan Ullah Sakib, Sharmin Jahan","doi":"10.3329/jninb.v9i1.65285","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65285","url":null,"abstract":"Background: Platelet-rich plasma (PRP) is a treatment that uses a patient's own blood, processed to concentrate platelets and growth factors, to treat erectile dysfunction (ED). Erectile dysfunction (ED) is a common condition that affects men of all ages and can have a significant impact on quality of life. Platelet rich plasma (PRP) is a newer treatment option that involves injecting a concentrated solution of platelets into the affected area to promote healing and tissue regeneration. Objective: The purpose of the present study was to evaluate the efficacy of platelet-rich plasma (PRP) in treating erectile dysfunction (ED). Methodology: A prospective study was conducted to evaluate the efficacy of platelet-rich plasma (PRP) in treating erectile dysfunction (ED) with a sample of 50 patients in Dhaka, Bangladesh during the period of January 2022 to June 2022. The patients received PRP treatment and the improvement in erectile function was measured through standardized questionnaires and scales. Data were collected predesigned data collection sheet. Results: The average age of the study subjects is 53.70 years. The mean scores of the IIEF-EF domain showed a statistically significant improvement from 18.50 ± 3.60 before the procedure to 20.71 ± 3.71 after 6th months (p = 0.002). Sexual satisfaction also showed a statistically significant improvement, with a mean score increasing from 6.00 ± 0.57 before the procedure to 8.00 ± 0.85 after 6th months (p = 0.016). However, there were no statistically significant changes in the mean scores for orgasmic function and sexual desire (p = 0.113 and p = 0.389, respectively). The mean score for general satisfaction showed a small but statistically significant increase from 5.00 ± 0.29 before the procedure to 5.38 ± 0.24 after the 1st month (p = 0.027). Conclusion: In conclusion platelet-rich plasma (PRP) application provides short-term improvement in erectile function. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):71-75","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.68176
Tahmida Firdousi, Kamrun Nahar Sweety, AKM Mohiuddin Bhuiyan, Afroza Sultana, Shamsun Nahar
Background: Ultrasonography is a very useful diagnostic tool for the detection of foetal weight. Objective: The purpose of the present study was to validate the ultrasonography for the detection of foetal weight. Methodology: This prospective cohort study was carried out in the Department of Obstetrics & Gynaecology at Rajshahi Medical Hospital, Rajshahi, Rajshahi, Bangladesh from July 2012 to June 2014 for a period of 2(two) years. Pregnant women with known gestational age at term (38 to 40 weeks of pregnancy), singleton pregnancy with longitudinal lie were included in this study. The patient was then taken to Dept. of Radiology & Imaging, RMCH. Ultrasonographic estimation of foetal weight was done from estimation of foetal abdominal circumference (AC), biparietal diameter (BPD) and foetal femur length (FL). Actual birth weights of babies were measured soon after their birth. The BPD, AC and FL were measured in centimetres and foetal weight was measured in grams. Actual birth weight is the first weight of now-born obtained after birth. This weight was measured within the first hour of life. Result: A total number of 245 pregnant women in term pregnancy were recruited as per inclusion and exclusion criteria. Majority of the women [91(37.1%)] belonged to the age group 19 to 29 years which was 174(71.0%) cases. Low birth weight was found in 12(4.9%) cases ultrasonographic examination and actual low birth weight was found in 15(6.0%) cases. Overweight was found in 13(5.2%) cases ultrasonographic examination and actual birth overweight was found in 9(3.7%) cases. The mean value and SD of foetal weight measured by USG was 2870.41 gms and 424.84 respectively. In case of actual birth weight, the mean and SD was 2936.20 gms and 456.71 respectively (p = 0.05). Conclusion: In conclusion estimation of foetal weight by ultrasonography is not significantly varied. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):16-19
{"title":"Diagnostic Accuracy of Ultrasonography for the Detection of Foetal Weight","authors":"Tahmida Firdousi, Kamrun Nahar Sweety, AKM Mohiuddin Bhuiyan, Afroza Sultana, Shamsun Nahar","doi":"10.3329/jninb.v9i1.68176","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.68176","url":null,"abstract":"Background: Ultrasonography is a very useful diagnostic tool for the detection of foetal weight. Objective: The purpose of the present study was to validate the ultrasonography for the detection of foetal weight. Methodology: This prospective cohort study was carried out in the Department of Obstetrics & Gynaecology at Rajshahi Medical Hospital, Rajshahi, Rajshahi, Bangladesh from July 2012 to June 2014 for a period of 2(two) years. Pregnant women with known gestational age at term (38 to 40 weeks of pregnancy), singleton pregnancy with longitudinal lie were included in this study. The patient was then taken to Dept. of Radiology & Imaging, RMCH. Ultrasonographic estimation of foetal weight was done from estimation of foetal abdominal circumference (AC), biparietal diameter (BPD) and foetal femur length (FL). Actual birth weights of babies were measured soon after their birth. The BPD, AC and FL were measured in centimetres and foetal weight was measured in grams. Actual birth weight is the first weight of now-born obtained after birth. This weight was measured within the first hour of life. Result: A total number of 245 pregnant women in term pregnancy were recruited as per inclusion and exclusion criteria. Majority of the women [91(37.1%)] belonged to the age group 19 to 29 years which was 174(71.0%) cases. Low birth weight was found in 12(4.9%) cases ultrasonographic examination and actual low birth weight was found in 15(6.0%) cases. Overweight was found in 13(5.2%) cases ultrasonographic examination and actual birth overweight was found in 9(3.7%) cases. The mean value and SD of foetal weight measured by USG was 2870.41 gms and 424.84 respectively. In case of actual birth weight, the mean and SD was 2936.20 gms and 456.71 respectively (p = 0.05). Conclusion: In conclusion estimation of foetal weight by ultrasonography is not significantly varied. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):16-19","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.65410
Ferdous Ara, Mohammad Sayeed Hassan, Md Abdullah Yusuf, Sheikh Farjana Sonia, Kaniz Fatema, Sabrina Islam, Md Badrul Alam, Quazi Deen Mohammad
Background: Therapeutic Plasma Exchange (TPE) is an effective therapeutic procedure for treating Myasthenia Gravis (MG). Objectives: The aim of study was to evaluate demographics, indications, adverse reactions and outcome of therapeutic plasma exchange in myasthenia gravis patients. Methodology: This prospective observational study was conducted in the Department of Transfusion Medicine at National Institute of Neurosciences and Hospital (NINS&H), Dhaka, Bangladesh from August 2014 to June 2022. All patients with Myasthenia Gravis who received therapeutic plasma exchange as a treatment during hospitalization were included in this study. Data were systematically recorded and these were variables of demographics, clinical indications, numbers of sessions, volume of exchanged plasma, clinical responses and complications during or after the procedure. Results: A total number of 72 patients had undergone 275 sessions of therapeutic plasma exchange among which 52(72.2%) cases were male and the mean age was 39.5±13.11 years. For each patient the number of therapeutic plasma exchange session and volume of plasma exchange were 3.69±1.016 (Range 2 to 7) and 2266.7±361.53 ml (Range 1400 to 3100) respectively. Anti-acetylcholine receptor antibody (Anti-ACR Ab) was positive in 44(61.1%) cases. Myasthenic crisis (n=45, 62.5%) was the most common indication of therapeutic plasma exchange followed by preoperative preparation for thymectomy (n=16, 22.2%) and worsening of myasthenic weakness (n=11, 15.3%). In 275 sessions of therapeutic plasma exchange, overall incidence of adverse reaction was in 26(9.45%) cases. Mild allergy (n=9, 3.27%) and pyrexia (n=5, 1.82%) were most commonly reported. Hypotension was reported in 4(1.46%) cases. Reactions were mild and were reversed by bed side managements. Response to treatment was observed in 80.5% (n=58) patients. 2(2.8%) patients of Myasthenia Gravis died; but death was unrelated to therapeutic plasma exchange. Conclusion: Therapeutic plasma exchange is rapidly effective therapy for myasthenic crisis, progressive myasthenia gravis and prior to thymectomy operation and it has adequate safety profile. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):16-23
{"title":"Therapeutic Plasma Exchange among Myasthenia Gravis Patients Attended at Referral Neurosciences Hospital in Bangladesh: A Single Centre Experience","authors":"Ferdous Ara, Mohammad Sayeed Hassan, Md Abdullah Yusuf, Sheikh Farjana Sonia, Kaniz Fatema, Sabrina Islam, Md Badrul Alam, Quazi Deen Mohammad","doi":"10.3329/jninb.v9i1.65410","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65410","url":null,"abstract":"Background: Therapeutic Plasma Exchange (TPE) is an effective therapeutic procedure for treating Myasthenia Gravis (MG). Objectives: The aim of study was to evaluate demographics, indications, adverse reactions and outcome of therapeutic plasma exchange in myasthenia gravis patients. Methodology: This prospective observational study was conducted in the Department of Transfusion Medicine at National Institute of Neurosciences and Hospital (NINS&H), Dhaka, Bangladesh from August 2014 to June 2022. All patients with Myasthenia Gravis who received therapeutic plasma exchange as a treatment during hospitalization were included in this study. Data were systematically recorded and these were variables of demographics, clinical indications, numbers of sessions, volume of exchanged plasma, clinical responses and complications during or after the procedure. Results: A total number of 72 patients had undergone 275 sessions of therapeutic plasma exchange among which 52(72.2%) cases were male and the mean age was 39.5±13.11 years. For each patient the number of therapeutic plasma exchange session and volume of plasma exchange were 3.69±1.016 (Range 2 to 7) and 2266.7±361.53 ml (Range 1400 to 3100) respectively. Anti-acetylcholine receptor antibody (Anti-ACR Ab) was positive in 44(61.1%) cases. Myasthenic crisis (n=45, 62.5%) was the most common indication of therapeutic plasma exchange followed by preoperative preparation for thymectomy (n=16, 22.2%) and worsening of myasthenic weakness (n=11, 15.3%). In 275 sessions of therapeutic plasma exchange, overall incidence of adverse reaction was in 26(9.45%) cases. Mild allergy (n=9, 3.27%) and pyrexia (n=5, 1.82%) were most commonly reported. Hypotension was reported in 4(1.46%) cases. Reactions were mild and were reversed by bed side managements. Response to treatment was observed in 80.5% (n=58) patients. 2(2.8%) patients of Myasthenia Gravis died; but death was unrelated to therapeutic plasma exchange. Conclusion: Therapeutic plasma exchange is rapidly effective therapy for myasthenic crisis, progressive myasthenia gravis and prior to thymectomy operation and it has adequate safety profile. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):16-23","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The use of spinal (subarachnoid) anaesthesia is often limited by the unwillingness of patients to remain awake during surgery. Objective: This study was undertaken to compare propofol and dexmedetomidine in terms of onset and recovery of sedation, haemodynamic effects, respiratory effects and adverse effects of both the drugs during elective Caesarian section under spinal anaesthesia. Methodology: This randomized clinical trial included 60 ASA (American Society of Anaesthesiologists) grade I patients undergoing elective Caesarean sections under Subarachnoid anaesthesia during the period January 2022 to June 2022. Patients were randomly allocated to one of two groups designated as Propofol group (Group A, n=30), who received Propofol in a single dose of 0.5mg/kg and Dexmedetomidine group (Group B, n=30), who received Dexmedetomidine in a single dose of 2mcg/kg. The onset of sedation i.e. time from iv (intravenous) injection of propofol or dexmedetomidine to closure of eye lids (OAA/S score of 3) and the arousal time from sedation i.e. time from closing of the eye lids to OAA/S score of 5 (patient is awake clinically) were noted. Any complication during operation was documented. Results: There was no significant difference of mean blood pressure and mean heart rate between the two groups in different time intervals (P>0.05). Time of onset of sedation was significantly delayed in Dexmedetomidine group (P<0.05). The arousal time i.e. duration of sedation was significantly longer with Dexmedetomidine than Propofol (P<0.05). Propofol was associated with significantly higher incidence of some adverse effects like pain in arm during drug administration than Dexmedetomidine (46.66% vs 10.0%, P<0.05). Significant percentage of patients was satisfied with dexmedetomidine than propofol (86.66% vs 13.33%, P<0.001). Conclusion: Duration of sedation is significantly longer with dexmedetomidine than propofol which is beneficial for the patient in single dose technique for sedation. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):65-70
背景:脊柱(蛛网膜下腔)麻醉的使用常常受到患者在手术过程中不愿意保持清醒的限制。目的:比较丙泊酚和右美托咪定在脊髓麻醉下择期剖宫产术中镇静起效和恢复、血流动力学作用、呼吸作用和不良反应。方法:这项随机临床试验包括60例ASA(美国麻醉师学会)一级患者，于2022年1月至2022年6月期间在蛛网膜下腔麻醉下进行选择性剖腹产。将患者随机分为两组:异丙酚组(A组，n=30)和右美托咪定组(B组，n=30)，分别给予异丙酚单次剂量0.5mg/kg和右美托咪定单次剂量2mcg/kg。记录镇静的起效时间，即从静脉注射异丙酚或右美托咪定到闭眼时间(OAA/S评分为3)和镇静的觉醒时间，即从闭眼到OAA/S评分为5(患者临床清醒)的时间。记录手术过程中任何并发症。结果:两组患者在不同时间间隔的平均血压、平均心率差异无统计学意义(P>0.05)。右美托咪定组患者镇静起效时间明显延迟(p < 0.05)。右美托咪定的唤醒时间即镇静时间明显长于异丙酚(P<0.05)。异丙酚在给药期间手臂疼痛等不良反应的发生率明显高于右美托咪定(46.66% vs 10.0%， P<0.05)。右美托咪定满意率显著高于异丙酚满意率(86.66% vs 13.33%， P<0.001)。结论:右美托咪定的镇静时间明显长于异丙酚，有利于单剂量镇静。孟加拉国国家神经科学研究所杂志，2023年1月;9(1):65-70
{"title":"Comparison between Effects of Propofol and Dexmedetomidine as Sedative in Elective Caesarean Section under Subarachnoid Anaesthesia","authors":"Md Enayet Karim Karim, RAM Mostafizur Rashid Mostafiz, Mohammad Saleh Akram Akram, Reza Ershad","doi":"10.3329/jninb.v9i1.65306","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65306","url":null,"abstract":"Background: The use of spinal (subarachnoid) anaesthesia is often limited by the unwillingness of patients to remain awake during surgery. Objective: This study was undertaken to compare propofol and dexmedetomidine in terms of onset and recovery of sedation, haemodynamic effects, respiratory effects and adverse effects of both the drugs during elective Caesarian section under spinal anaesthesia. Methodology: This randomized clinical trial included 60 ASA (American Society of Anaesthesiologists) grade I patients undergoing elective Caesarean sections under Subarachnoid anaesthesia during the period January 2022 to June 2022. Patients were randomly allocated to one of two groups designated as Propofol group (Group A, n=30), who received Propofol in a single dose of 0.5mg/kg and Dexmedetomidine group (Group B, n=30), who received Dexmedetomidine in a single dose of 2mcg/kg. The onset of sedation i.e. time from iv (intravenous) injection of propofol or dexmedetomidine to closure of eye lids (OAA/S score of 3) and the arousal time from sedation i.e. time from closing of the eye lids to OAA/S score of 5 (patient is awake clinically) were noted. Any complication during operation was documented. Results: There was no significant difference of mean blood pressure and mean heart rate between the two groups in different time intervals (P>0.05). Time of onset of sedation was significantly delayed in Dexmedetomidine group (P<0.05). The arousal time i.e. duration of sedation was significantly longer with Dexmedetomidine than Propofol (P<0.05). Propofol was associated with significantly higher incidence of some adverse effects like pain in arm during drug administration than Dexmedetomidine (46.66% vs 10.0%, P<0.05). Significant percentage of patients was satisfied with dexmedetomidine than propofol (86.66% vs 13.33%, P<0.001). Conclusion: Duration of sedation is significantly longer with dexmedetomidine than propofol which is beneficial for the patient in single dose technique for sedation. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):65-70","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.65360
Kamrun Nahar Sweety, Nasreen Haque, Nowshafreen Chowdhury, Razia Begum, Laila Nazneen Khan, Rumana Sultana, Naznin Rashid Shewly
Background: Ultrasonography intervention in delivery is highly sensitive and primary important for further tests of foetal well-being. Objective: The purpose of the present study was to observe the correlation of estimated foetal weight with neonatal birth weight. Methodology: This was a cross-sectional study on patients at the Labour Ward of Department of Obstetrics and Gynaecology at Sir Salimullah Medical College and Mitford Hospiptal, Dhaka, Bangladesh for six months. The women were selected who had normal pregnancy with early ultrasounographic examination for confirmation of gestational age, singleton live foetus, ultrasound examination for pregnancy profile done within 3 days before delivery. A sonographic foetal weight was estimated by using measurements of foetal body parts-biparietal diameter, abdominal circumference and femoral length. To measure the femur length, first a projection was made that shows a transverse section of one of the long bones, then scan at 900 to this to obtain a longitudinal section. Results: A total number of 100 patients were recruited for this study. The mean (±SD) sonographically estimated foetal weight was 3074±534gm with ranged from 2100 to 4100 gm. The mean (±SD) neonatal birth weight was 2978±466 gm with ranged from 2500 to 3800 gm (p<0.05). Sonographically estimated foetal weight less than 3000 g were correlated with neonatal birth weight. Out of the 100 cases 57(57.0%) cases had less than 3000 g estimated foetal weight and 43(43.0%) cases had 3000 g or more than 3000gm estimated foetal weight Sonographically. Among the 57 cases, which were less than 3000 g by Sonographically, 41 cases were less than 3000 g and 16 cases were found 3000 g or more than 3000 g in neonatal birth weight. Conclusion: Ultrasonography has definite value in the diagnosis of estimated foetal weight and can be regarded as a sensitive and specific imaging modality for pre-operative discrimination of the pregnant women. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):42-47
{"title":"Estimation of Foetal Weight by Ultrasonography and Neonate at Birth","authors":"Kamrun Nahar Sweety, Nasreen Haque, Nowshafreen Chowdhury, Razia Begum, Laila Nazneen Khan, Rumana Sultana, Naznin Rashid Shewly","doi":"10.3329/jninb.v9i1.65360","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65360","url":null,"abstract":"Background: Ultrasonography intervention in delivery is highly sensitive and primary important for further tests of foetal well-being. Objective: The purpose of the present study was to observe the correlation of estimated foetal weight with neonatal birth weight. Methodology: This was a cross-sectional study on patients at the Labour Ward of Department of Obstetrics and Gynaecology at Sir Salimullah Medical College and Mitford Hospiptal, Dhaka, Bangladesh for six months. The women were selected who had normal pregnancy with early ultrasounographic examination for confirmation of gestational age, singleton live foetus, ultrasound examination for pregnancy profile done within 3 days before delivery. A sonographic foetal weight was estimated by using measurements of foetal body parts-biparietal diameter, abdominal circumference and femoral length. To measure the femur length, first a projection was made that shows a transverse section of one of the long bones, then scan at 900 to this to obtain a longitudinal section. Results: A total number of 100 patients were recruited for this study. The mean (±SD) sonographically estimated foetal weight was 3074±534gm with ranged from 2100 to 4100 gm. The mean (±SD) neonatal birth weight was 2978±466 gm with ranged from 2500 to 3800 gm (p<0.05). Sonographically estimated foetal weight less than 3000 g were correlated with neonatal birth weight. Out of the 100 cases 57(57.0%) cases had less than 3000 g estimated foetal weight and 43(43.0%) cases had 3000 g or more than 3000gm estimated foetal weight Sonographically. Among the 57 cases, which were less than 3000 g by Sonographically, 41 cases were less than 3000 g and 16 cases were found 3000 g or more than 3000 g in neonatal birth weight. Conclusion: Ultrasonography has definite value in the diagnosis of estimated foetal weight and can be regarded as a sensitive and specific imaging modality for pre-operative discrimination of the pregnant women. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):42-47","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.68149
ATM Hasibul Hasan, Subir Chandra Das, Muhammad Sougatul Islam, Mohaimen Mansur, Nushrat Khan, Mohammad Shah Jahirul Hoque Chowdhury
Background: The influence of COVID-19 on in hospital mortality and short-term outcome of acute ischemic stroke is not well known. Objective: The purpose of the present study was to analyze the overall impact of COVID-19 patients and 30-day outcomes of acute ischemic stroke patients. Methodology: This was a hospital-based case-control study from February to May 2021 conducted in stroke unit of National Institute of Neurosciences and Hospital. Consecutive ischemic stroke patients contracting COVID-19 infection was considered as case group and similar patients, negative for SARS CoV-2 on RT-PCR from nasal swab were considered for control group following the inclusion and exclusion criteria. Results: A total number of 50 cases and 99 similar control were taken. Although a significant proportion of control group were male (76.8% vs 50%), there was similar age distribution in both groups. Diabetes and Multiple comorbid conditions and lymphopenia were significantly (p value of <0.001) more common among the case (1% versus 22%, 28.3% versus 56% and 5.1% versus 54%) in contrast to hypertension and lymphocytosis which was more frequent in control group (42.4% versus 10% and 94.9% versus 46%). Though the cases had a significantly (p value <0.001) higher NIHSS score at admission (median IQR 7 versus 13) and longer hospital stay (median IQR 6 days versus 14 days). Male stroke patients were 4.7 times more likely to die in-hospital compared to female patients. The risk of mortality were 5 times higher among cases. Conclusion: COVID positive stroke cases have more severe disease at admission and longer hospital stays and the risk of mortality is 5 times higher in COVID positive stroke cases with a significant male dominance. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):11-15
背景:COVID-19对急性缺血性脑卒中住院死亡率和短期预后的影响尚不清楚。目的:本研究的目的是分析COVID-19患者和急性缺血性脑卒中患者30天预后的总体影响。方法:这是一项基于医院的病例对照研究，于2021年2月至5月在国家神经科学与医院研究所卒中单元进行。连续缺血性卒中患者感染COVID-19为病例组，鼻拭子RT-PCR阴性的类似患者为对照组，符合纳入和排除标准。结果:共50例，对照组99例。虽然对照组男性占比显著(76.8% vs 50%)，但两组患者的年龄分布相似。与高血压和淋巴细胞增多症相比，糖尿病和多重合并症和淋巴细胞减少症在该病例中更为常见(p值为<0.001)(1%对22%，28.3%对56%，5.1%对54%)，而高血压和淋巴细胞增多症在对照组中更为常见(42.4%对10%，94.9%对46%)。虽然这些病例入院时的NIHSS评分明显(p值<0.001)较高(IQR中位数为7比13)，住院时间较长(IQR中位数为6天比14天)。男性中风患者在医院死亡的可能性是女性患者的4.7倍。病例中死亡风险高出5倍。结论:COVID阳性脑卒中患者入院时病情更严重，住院时间更长，死亡风险高5倍，且男性优势明显。孟加拉国国家神经科学研究所杂志，2023年1月;9(1):11-15
{"title":"In Hospital Mortality and Short-Term Outcomes of Acute Ischemic Stroke Patients Contracting SARS CoV-2 Infection: Experience from a Dedicated Stroke Unit in Bangladesh","authors":"ATM Hasibul Hasan, Subir Chandra Das, Muhammad Sougatul Islam, Mohaimen Mansur, Nushrat Khan, Mohammad Shah Jahirul Hoque Chowdhury","doi":"10.3329/jninb.v9i1.68149","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.68149","url":null,"abstract":"Background: The influence of COVID-19 on in hospital mortality and short-term outcome of acute ischemic stroke is not well known. Objective: The purpose of the present study was to analyze the overall impact of COVID-19 patients and 30-day outcomes of acute ischemic stroke patients. Methodology: This was a hospital-based case-control study from February to May 2021 conducted in stroke unit of National Institute of Neurosciences and Hospital. Consecutive ischemic stroke patients contracting COVID-19 infection was considered as case group and similar patients, negative for SARS CoV-2 on RT-PCR from nasal swab were considered for control group following the inclusion and exclusion criteria. Results: A total number of 50 cases and 99 similar control were taken. Although a significant proportion of control group were male (76.8% vs 50%), there was similar age distribution in both groups. Diabetes and Multiple comorbid conditions and lymphopenia were significantly (p value of <0.001) more common among the case (1% versus 22%, 28.3% versus 56% and 5.1% versus 54%) in contrast to hypertension and lymphocytosis which was more frequent in control group (42.4% versus 10% and 94.9% versus 46%). Though the cases had a significantly (p value <0.001) higher NIHSS score at admission (median IQR 7 versus 13) and longer hospital stay (median IQR 6 days versus 14 days). Male stroke patients were 4.7 times more likely to die in-hospital compared to female patients. The risk of mortality were 5 times higher among cases. Conclusion: COVID positive stroke cases have more severe disease at admission and longer hospital stays and the risk of mortality is 5 times higher in COVID positive stroke cases with a significant male dominance. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):11-15","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.65382
Shahana Sarwar, Muhammad Tanvir Mohith, Muhammad Marnush, Muhammad Nafees Hussain, Md Sayedur Rahman Rahman, Tahmina Begum
Background: Several drugs were administered to patients with COVID-19, focusing on their antiviral, immunomodulatory, or anti-inflammatory actions, which could potentially present risk since most of these medicines have the potential to cause numerous adverse effects. Objective: This study aimed to observe the incidence of suspected adverse events of selected medicines among COVID-like ill (CLI) patients. Methodology: A prospective analysis was performed from February 15, 2021, to June 15, 2021, upon 223 CLI patients. CLI patients were enrolled from the National Institute of Diseases of the Chest and Hospital. The incidence of suspected adverse events were assessed among CLI patients, the laboratory investigations values of SGPT, RBS, serum electrolytes, and serum creatinine of day one and day five and interpreted the 12-lead ECG tracing paper of the same days assessed hepatotoxicity, nephrotoxicity, cardiotoxicity, and metabolic disorders. Results: The result showed the incidence of adverse events was 21.5% in CLI patients. Only the incidence of hepatotoxicity was more (12.55%) among CLI patients but statistically not significant (p > 0.05). In CLI patients who had co-morbidities, the incidence of adverse events was relatively less and only a significant difference was seen among diabetes mellitus patients (p ≤ 0.05). Conclusion: This study showed that the rate of adverse events was present in CLI patients when treated with the same specific drug of interest in addition to other medicines they received. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):35-41
{"title":"Distribution and Determinants of Suspected Adverse Events among COVID like Illness (CLI) Patients with Different Comorbidities","authors":"Shahana Sarwar, Muhammad Tanvir Mohith, Muhammad Marnush, Muhammad Nafees Hussain, Md Sayedur Rahman Rahman, Tahmina Begum","doi":"10.3329/jninb.v9i1.65382","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65382","url":null,"abstract":"Background: Several drugs were administered to patients with COVID-19, focusing on their antiviral, immunomodulatory, or anti-inflammatory actions, which could potentially present risk since most of these medicines have the potential to cause numerous adverse effects. Objective: This study aimed to observe the incidence of suspected adverse events of selected medicines among COVID-like ill (CLI) patients. Methodology: A prospective analysis was performed from February 15, 2021, to June 15, 2021, upon 223 CLI patients. CLI patients were enrolled from the National Institute of Diseases of the Chest and Hospital. The incidence of suspected adverse events were assessed among CLI patients, the laboratory investigations values of SGPT, RBS, serum electrolytes, and serum creatinine of day one and day five and interpreted the 12-lead ECG tracing paper of the same days assessed hepatotoxicity, nephrotoxicity, cardiotoxicity, and metabolic disorders. Results: The result showed the incidence of adverse events was 21.5% in CLI patients. Only the incidence of hepatotoxicity was more (12.55%) among CLI patients but statistically not significant (p > 0.05). In CLI patients who had co-morbidities, the incidence of adverse events was relatively less and only a significant difference was seen among diabetes mellitus patients (p ≤ 0.05). Conclusion: This study showed that the rate of adverse events was present in CLI patients when treated with the same specific drug of interest in addition to other medicines they received. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):35-41","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.3329/jninb.v9i1.65412
Mohammad Nur Uddin, Maliha Hakim, Tahira Zannat, Md Al Amin, Mohammad Abdur Rauf Dolan, Md Abdullah Yusuf, Mashfiqul Hasan, Muhammad Saiful Islam, Swapon Kumar Ray, Md Faizul Islam Chowdhury
Background: Hyperhomocysteinemia is emerging as a possible risk factor for stroke, possibly because of accelerated atherosclerosis. Objectives: This study was conducted to evaluate the association between the serum homocysteine level and ischemic stroke in young Bangladeshi patients. Methodology: This cross-sectional study was carried out among patients 18 to 40 years of either gender with sign and symptoms of acute focal neurological deficit, in the Department of Medicine of Dhaka Medical College Hospital, Dhaka, from January 2015 to December 2015. History taking and physical examination were done in a predesigned data collection sheet. Then required investigations like CT-scan of brain, fasting serum homocysteine, fasting blood sugar, 2 hours ABF blood glucose, HbA1c and fasting lipid profile were done. Results: Out of 96 patients after completing brain imaging 61(65.0%) patients were found suffering from ischemic stroke. Among the patients 74 had normal homocysteine level, 17 patients had moderate hyperhomocysteinemia and 5 patients had intermediate hyperhomocysteinemia. Mean levels of fasting serum homocysteine were significantly higher in patients those had ischemic stroke (16.02 μmol/L, 95% CI: 12.87 to 19.87) compared with those who did not have ischemic stroke (10.47 μmol/L, 95% CI: 9.16 to 11.95, P<0.001). Logistic regression showed fasting homocysteine as an important independent risk factor, with an adjusted OR of 1.1 (95% CI: 1.1 to 1.2; p=0.04966) for every 1 μmol/L increase in homocysteine. Conclusion: The relationship between increasing homocysteine and ischemic stroke risk is strong, graded, and significant. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):24-29
{"title":"Association of Serum Homocysteine Level with Acute Ischaemic Stroke among Young Adult Patients: Experience at a Largest Medical College Hospital in Bangladesh","authors":"Mohammad Nur Uddin, Maliha Hakim, Tahira Zannat, Md Al Amin, Mohammad Abdur Rauf Dolan, Md Abdullah Yusuf, Mashfiqul Hasan, Muhammad Saiful Islam, Swapon Kumar Ray, Md Faizul Islam Chowdhury","doi":"10.3329/jninb.v9i1.65412","DOIUrl":"https://doi.org/10.3329/jninb.v9i1.65412","url":null,"abstract":"Background: Hyperhomocysteinemia is emerging as a possible risk factor for stroke, possibly because of accelerated atherosclerosis. Objectives: This study was conducted to evaluate the association between the serum homocysteine level and ischemic stroke in young Bangladeshi patients. Methodology: This cross-sectional study was carried out among patients 18 to 40 years of either gender with sign and symptoms of acute focal neurological deficit, in the Department of Medicine of Dhaka Medical College Hospital, Dhaka, from January 2015 to December 2015. History taking and physical examination were done in a predesigned data collection sheet. Then required investigations like CT-scan of brain, fasting serum homocysteine, fasting blood sugar, 2 hours ABF blood glucose, HbA1c and fasting lipid profile were done. Results: Out of 96 patients after completing brain imaging 61(65.0%) patients were found suffering from ischemic stroke. Among the patients 74 had normal homocysteine level, 17 patients had moderate hyperhomocysteinemia and 5 patients had intermediate hyperhomocysteinemia. Mean levels of fasting serum homocysteine were significantly higher in patients those had ischemic stroke (16.02 μmol/L, 95% CI: 12.87 to 19.87) compared with those who did not have ischemic stroke (10.47 μmol/L, 95% CI: 9.16 to 11.95, P<0.001). Logistic regression showed fasting homocysteine as an important independent risk factor, with an adjusted OR of 1.1 (95% CI: 1.1 to 1.2; p=0.04966) for every 1 μmol/L increase in homocysteine. Conclusion: The relationship between increasing homocysteine and ischemic stroke risk is strong, graded, and significant. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):24-29","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63768
S. Begum, Toufiqua Ahmed, M. A. Hossain, M. M. Akhtar, Mahmuda Akter, Sharmin Aktar Soma, M. Kamruzzaman
Background: Conventional methods like Erich’s arch bars and eyelet wires are currently most common methods for achieving temporary inter-maxillary fixation (IMF). Objectives: The purpose of the present study was to compare the efficacy of Self-tapping screws over Erich’s arch bar wiring for inter maxillary fixation in the treatment of mandibular fractures. Methodology: This was a randomized control trial study. Study duration was one year from October 2014 to September 2015. This study involved patients with mandibular fractures aged 22 to 65 years who visited Department of Oral & Maxillofacial Surgery at Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. After random sampling according to inclusion and exclusion criteria surgical treatment was done by miniplate osteosynthesis. Study population were divided into two groups. In group A, temporary MMF was done with Erich’s arch bar and in group B treatment was given with self-tapping screws. The study outcomes were total time required for achieving temporary MMF, number of wire stick injury, stability of occlusion and oral hygiene index. All the parameters were measured preoperatively and postoperatively for 14 days up to removal of screws or arch bars. Results: The mean time taken for temporary MMF was 11.31±2.46 min with screws as compared to 84.72±14.30 min with Erich’s arch bar. Mean number of perforations were significantly more in group A. Occlusion stability was 69.2% in group A and 84.6% in group B. The mean value of plaque index in group A was 2.85±0.25 and in group B was 1.15± 0.16. Conclusion: In conclusion, plaque deposition was more in group A. Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):175-180
背景:传统的方法如Erich 's弓棒和孔丝目前是实现临时上颌间固定(IMF)最常见的方法。目的:本研究的目的是比较自攻螺钉与Erich弓棒钢丝在颌骨间固定治疗下颌骨骨折的疗效。方法:这是一项随机对照试验研究。研究时间为一年，从2014年10月到2015年9月。本研究纳入了在孟加拉国达卡的Bangabandhu Sheikh Mujib医科大学口腔颌面外科就诊的22至65岁的下颌骨折患者。根据纳入和排除标准随机抽样后，采用微型钢板内固定进行手术治疗。研究人群分为两组。A组采用Erich 's弓棒进行临时MMF治疗，B组采用自攻螺钉治疗。研究结果为达到暂时性MMF所需的总时间、丝棒损伤数、咬合稳定性和口腔卫生指标。术前和术后14天测量所有参数，直至取出螺钉或弓杆。结果:螺钉治疗临时MMF的平均时间为11.31±2.46 min，而Erich弓棒治疗的平均时间为84.72±14.30 min。A组平均穿孔数明显多于A组，牙合稳定性为69.2%，B组为84.6%。A组斑块指数平均值为2.85±0.25,B组为1.15±0.16。结论:综上所述，a组斑块沉积更多。Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):175-180
{"title":"Comparison of Self-Tapping Screws Versus Erich’s Arch Bar Wiring for Occlusion Maintenance in the Surgical Management of Mandibular Fracture: A Randomized Control Trial","authors":"S. Begum, Toufiqua Ahmed, M. A. Hossain, M. M. Akhtar, Mahmuda Akter, Sharmin Aktar Soma, M. Kamruzzaman","doi":"10.3329/jninb.v8i2.63768","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63768","url":null,"abstract":"Background: Conventional methods like Erich’s arch bars and eyelet wires are currently most common methods for achieving temporary inter-maxillary fixation (IMF). \u0000Objectives: The purpose of the present study was to compare the efficacy of Self-tapping screws over Erich’s arch bar wiring for inter maxillary fixation in the treatment of mandibular fractures. \u0000Methodology: This was a randomized control trial study. Study duration was one year from October 2014 to September 2015. This study involved patients with mandibular fractures aged 22 to 65 years who visited Department of Oral & Maxillofacial Surgery at Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. After random sampling according to inclusion and exclusion criteria surgical treatment was done by miniplate osteosynthesis. Study population were divided into two groups. In group A, temporary MMF was done with Erich’s arch bar and in group B treatment was given with self-tapping screws. The study outcomes were total time required for achieving temporary MMF, number of wire stick injury, stability of occlusion and oral hygiene index. All the parameters were measured preoperatively and postoperatively for 14 days up to removal of screws or arch bars. \u0000Results: The mean time taken for temporary MMF was 11.31±2.46 min with screws as compared to 84.72±14.30 min with Erich’s arch bar. Mean number of perforations were significantly more in group A. Occlusion stability was 69.2% in group A and 84.6% in group B. The mean value of plaque index in group A was 2.85±0.25 and in group B was 1.15± 0.16. \u0000Conclusion: In conclusion, plaque deposition was more in group A. \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):175-180","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78117290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63775
M. Kabir, Md Aminul Hasanat, Iftekhar Md Kudrat E Khuda, R. Akter, M. Haque, R. Islam
Background: Accurate detection of astrocytomas is very difficult. Objective: The purpose of the present study was to evaluate the usefulness of Magnetic Resonance Imaging (MRI) in detection of intracranial astrocytoma. Methodology: This cross sectional study was carried out in the Department of Radiology and Imaging with the collaboration of Department of Neurosurgery and Department of Pathology at Sir Salimullah Medical College (SSMC & MH), Dhaka from January 2013 to December 2013 for a period of one (1) year. Prior to the commencement of this study, the research protocol was approved by the ethical committee (Local Ethical committee) of SSMC. All the patients presented with clinically diagnosed cases of intracranial astrocytoma who were attended in the OPD and IPD were included as study population. The sampling technique was purposive, non-random sampling method. MRI was performed in all cases. The postoperative resected tissues were examined histopathological in the respective department. Then the collected reports were compared with findings of MRI. Results: The sample size of the present study was 48 astrocytoma patients. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of MRI for the diagnosis of astrocytoma are 92.0%, 80.0%, 96.0%, 67.0% and 90.3% respectively. Conclusion: In conclusion MRI has a high diagnostic validity for the detection of astrocytoma. Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):202-205
{"title":"Astrocytoma Detection with Magnetic Resonance Imaging among Patients attended at a Tertiary Care Hospital in Dhaka City","authors":"M. Kabir, Md Aminul Hasanat, Iftekhar Md Kudrat E Khuda, R. Akter, M. Haque, R. Islam","doi":"10.3329/jninb.v8i2.63775","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63775","url":null,"abstract":"Background: Accurate detection of astrocytomas is very difficult. \u0000Objective: The purpose of the present study was to evaluate the usefulness of Magnetic Resonance Imaging (MRI) in detection of intracranial astrocytoma. \u0000Methodology: This cross sectional study was carried out in the Department of Radiology and Imaging with the collaboration of Department of Neurosurgery and Department of Pathology at Sir Salimullah Medical College (SSMC & MH), Dhaka from January 2013 to December 2013 for a period of one (1) year. Prior to the commencement of this study, the research protocol was approved by the ethical committee (Local Ethical committee) of SSMC. All the patients presented with clinically diagnosed cases of intracranial astrocytoma who were attended in the OPD and IPD were included as study population. The sampling technique was purposive, non-random sampling method. MRI was performed in all cases. The postoperative resected tissues were examined histopathological in the respective department. Then the collected reports were compared with findings of MRI. \u0000Results: The sample size of the present study was 48 astrocytoma patients. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of MRI for the diagnosis of astrocytoma are 92.0%, 80.0%, 96.0%, 67.0% and 90.3% respectively. \u0000Conclusion: In conclusion MRI has a high diagnostic validity for the detection of astrocytoma. \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):202-205","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87640697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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