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Accuracy of a calibration method based on cone beam computed tomography and intraoral scanner data registration for robot-assisted implant placement: An in vitro study. 基于锥形束计算机断层扫描和口内扫描仪数据注册的校准方法在机器人辅助种植体植入中的准确性:体外研究
IF 4.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-07 DOI: 10.1016/j.prosdent.2024.08.009
Yi Li, Jizhe Lyu, Xunning Cao, Yin Zhou, Jianguo Tan, Xiaoqiang Liu

Statement of problem: Robotic systems have shown promise for implant placement because of their accuracy in identifying surgical positions. However, research on the accuracy of patient calibration methods based on cone beam computed tomography (CBCT) and intraoral scanner (IOS) data registration is lacking.

Purpose: The purpose of this in vitro study was to develop a calibration method based on the registration of CBCT and IOS data of a robot-assisted system for implant placement, evaluate the accuracy of this calibration method, and explore the accuracy of robot-assisted surgery at different implant positions.

Material and methods: Twenty standardized, polyurethane, partially edentulous maxillary typodonts were divided into 2 groups: one group used a calibration method based solely on CBCT data (CBCT group), and the other used a calibration method based on the registration of CBCT and IOS data (IOS group). Four implants were planned for each typodont in the right second premolar, left central incisor, left first premolar, and left second molar positions. The robot performed the osteotomies and implant placement step by step according to the preoperative plan. The operating software program automatically measured the deviation between the planned and actual implant position. Two-way analysis of variance (ANOVA) and the least significant difference (LSD) post hoc test (α=.05) were used to analyze differences between the test groups.

Results: The angular deviation and 3-dimensional deviations at implant platform and apex between the 2 calibration methods did not significantly differ among the 4 implant positions (P>.05). The horizontal and depth deviations at the implant platform and apex levels between the 2 calibration methods did not significantly differ among the 4 implant positions (P>.05). In the anterior region (left central incisor), the CBCT group showed higher horizontal deviation at both the implant platform and apex compared with the IOS group (P<.05). Conversely, the IOS group had greater depth deviation at both the implant platform and apex than the CBCT group (P<.05). In the posterior region, with or without distal extension (right second premolar, left first premolar, and left second molar), no statistically significant differences were found between the 2 calibration methods (P>.05).

Conclusions: The calibration method that was based on the registration of CBCT and IOS data demonstrated high accuracy. No significant differences in the accuracy of the calibration methods for robot-assisted implant placement were found between the CBCT group and IOS group.

问题陈述:机器人系统在确定手术位置方面非常准确,因此在种植体植入方面大有可为。目的:本体外研究的目的是开发一种基于机器人辅助系统的 CBCT 和 IOS 数据注册的种植体植入校准方法,评估该校准方法的准确性,并探索机器人辅助手术在不同种植体位置的准确性:将 20 个标准化、聚氨酯、部分无牙颌的上颌牙型分为两组:一组使用完全基于 CBCT 数据的校准方法(CBCT 组),另一组使用基于 CBCT 和 IOS 数据注册的校准方法(IOS 组)。每个类型牙的右第二前磨牙、左中切牙、左第一前磨牙和左第二磨牙位置都计划植入四个种植体。机器人根据术前计划逐步进行截骨和种植体植入。操作软件程序自动测量计划种植体位置与实际种植体位置之间的偏差。采用双向方差分析(ANOVA)和最小显著性差异(LSD)事后检验(α=.05)分析测试组之间的差异:两种校准方法在种植体平台和种植体顶点的角度偏差和三维偏差在 4 个种植体位置之间没有显著差异(P>.05)。两种校准方法在种植体平台和种植体顶点的水平偏差和深度偏差在 4 个种植体位置之间没有明显差异(P>.05)。在前牙区(左中切牙),CBCT 组与 IOS 组相比,种植体平台和顶点的水平偏差更大(P.05):基于 CBCT 和 IOS 数据注册的校准方法具有很高的准确性。CBCT 组和 IOS 组在机器人辅助种植体植入的校准方法准确性上没有明显差异。
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引用次数: 0
Can nonhazardous postprocessing cleaning solutions enable adequate surface properties for printed dental casts in different resins? 非危险性后处理清洁解决方案能否使不同树脂的印刷牙科铸模具有适当的表面特性?
IF 4.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-05 DOI: 10.1016/j.prosdent.2024.07.034
Gulce Çakmak, Gabriela Panca Sabatini, Marcella Silva de Paula, Ahmet Orgev, Çiğdem Kahveci, Marta Revilla-Léon, Burak Yilmaz

Statement of problem: Printed casts and dental devices and prostheses are increasingly being used, and the ecological impact of additive manufacturing should be considered in addition to the fabrication accuracy and surface properties of the printed object. To overcome the ecological drawbacks of alcohol postprocessing, water-washable, 3-dimensionally (3D) printable cast resins and postprocessing cleaning solutions that do not include alcohol have been introduced. However, whether using only water rather than chemical solvents would enable the surface smoothness and hardness required for accurate diagnostic and prosthetic procedures is unknown.

Purpose: The purpose of this in vitro study was to evaluate the effect of resin type (water-washable or nonwater washable) and postprocessing cleaning solution on the surface roughness and microhardness of 3D printed dental cast resins.

Material and methods: One hundred eight disk-shaped specimens (Ø10×2 mm) were additively manufactured (AM) from 3 dental cast resins: 2 water-washable (Epax (WW1) and Phrozen (WW2)) and 1 nonwater-washable resin (KeyModel Ultra resin-beige (NWW)) with a printer (n=36). Specimens in each resin type were divided into 3 groups for the application of postprocessing cleaning solution (water, 98% isopropyl alcohol [IPA] or methyl ether solvent) and polymerized after cleaning. The surface roughness (Ra, µm) and Vickers microhardness (HV) were measured. Laser microscope images were made of 1 specimen from each group.

Results: NWW-IPA (control group) had a similar Ra to WW2-water (P=.81) and WW2-methyl ether solvent (P=.511). NWW-IPA had lower HV than WW2-water (P<.001) and WW1-methyl ether solvent (P=.001). Solutions had no significant effect on the Ra of WW1 (P≥.554) and WW2 (P≥.805). WW1 had higher surface irregularities with water, whereas no significant difference was visually observed with IPA or methyl ether solvent. Solutions had a similar effect on the surface of WW2 when evaluated visually with the laser microscope.

Conclusions: Resin type and postprocessing cleaning solution affected the surface roughness and microhardness of 3D printed dental cast resins, except for the surface roughness of tested water-washable resins. Water or methyl ether solvent cleaned water-washable resin (WW2) had surface roughness and hardness similar to commonly used nonwater-washable cast resin.

问题简介:打印铸模和牙科设备及假体的使用越来越多,除了考虑打印物体的制造精度和表面特性外,还应该考虑增材制造对生态环境的影响。为了克服酒精后处理的生态弊端,人们推出了可水洗的三维(3D)可打印铸模树脂和不含酒精的后处理清洁溶液。目的:本体外研究旨在评估树脂类型(可水洗或不可水洗)和后处理清洁溶液对 3D 打印牙科铸模树脂表面粗糙度和微硬度的影响:用打印机对 3 种牙科铸造树脂:2 种可水洗树脂(Epax (WW1) 和 Phrozen (WW2))和 1 种不可水洗树脂(KeyModel Ultra 树脂-米色 (NWW))进行了加成制造(AM),共制作了 18 个圆盘状试样(Ø10×2 毫米)(n=36)。每种树脂的试样分为 3 组,分别使用后处理清洗液(水、98% 异丙醇 [IPA] 或甲醚溶剂),清洗后进行聚合。测量表面粗糙度(Ra,µm)和维氏显微硬度(HV)。对每组中的一个试样进行激光显微镜成像:NWW-IPA(对照组)的 Ra 值与 WW2-水(P=.81)和 WW2-甲醚溶剂(P=.511)相似。NWW-IPA 的 HV 值低于 WW2-水(WW1 的 Pa 值(P≥.554)和 WW2 的 Pa 值(P≥.805))。WW1 在水中的表面不规则度较高,而在 IPA 或甲醚溶剂中则没有明显差异。用激光显微镜目测,溶液对 WW2 表面的影响相似:树脂类型和后处理清洁溶液会影响 3D 打印牙科铸模树脂的表面粗糙度和显微硬度,但测试的水洗树脂的表面粗糙度除外。水或甲醚溶剂清洗过的水洗树脂(WW2)的表面粗糙度和硬度与常用的非水洗铸造树脂相似。
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引用次数: 0
Response to Letter to the Editor regarding, "The application of 3D printing in dentistry: A bibliometric analysis from 2012 to 2023 (J Prosthet Dent. 2024 Jul 1)". 对有关 "3D 打印在牙科中的应用:从 2012 年到 2023 年的文献计量分析 (J Prosthet Dent. 2024 Jul 1)"。
IF 4.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-05 DOI: 10.1016/j.prosdent.2024.07.041
Guangwei Chen, Jingkun Zhang, Jianfeng He, Yongqi Li, Chengwei Li, Zhiyan Lin, Huilin Wu, Libin Zhou
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引用次数: 0
Evaluation of adherence of Candida albicans to differently manufactured acrylic resin denture base materials. 评估白色念珠菌对不同制造工艺的丙烯酸树脂义齿基托材料的粘附性。
IF 4.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-05 DOI: 10.1016/j.prosdent.2024.07.040
William Emory Linder, Wendy Auclair Clark, Roland Arnold, Ingeborg De Kok, David A Felton

Statement of problem: Though computer-aided design and computer-aided manufactured (CAD-CAM) denture bases have become popular, evidence on the ability of C. albicans cells to adhere to these denture bases is lacking.

Purpose: The purpose of this in vitro study was to evaluate the adherence of Candida albicans to differently manufactured acrylic resin denture bases.

Material and methods: Acrylic resin disks were fabricated using a total of 6 different fabrication methods (compression molding, injection molding, CAD-CAM milling, and rapid prototyping on 3 different printers with 3 different resins). Each material was evaluated for adherence of C. albicans using 2 different experimental methods - suspension in inoculated tryptic soy broth (TSB) or placed onto a uniform lawn of C. albicans on tryptone soya agar (TSA) with 5% sheep's blood. Attached cells were quantified by spiral plating and then used to re-inoculate sterile plates. Logarithmic transformation was completed to normalize data. For the broth suspension, the Kruskal-Wallis test was used to identify any differences between the 6 specimen types in terms of recovery, and the Dunn test was used for post hoc analysis. For the microbial lawn experiment, 1-way analysis of variance (ANOVA) and then the Tukey Honestly Significant Difference (HSD) post hoc test were used.

Results: Statistically significant differences were found between the numbers of adherent cells based on manufacturing method and between experimental designs (P<.05). All resins demonstrated growth with re-inoculation.

Conclusions: Though statistical significance was noted, neither experimental technique demonstrated what is likely a clinically significant preferential binding to any particular resin surface. Attached Candida cells are effective carriers of pathogens to uninfected surfaces. Further studies are indicated for potential virulence factors and differences in printed resins.

问题陈述:尽管计算机辅助设计和计算机辅助制造(CAD-CAM)义齿基托已变得很流行,但仍缺乏有关白色念珠菌细胞粘附在这些义齿基托上的能力的证据。目的:本体外研究的目的是评估白色念珠菌粘附在不同制造方法的丙烯酸树脂义齿基托上的能力:使用总共 6 种不同的制造方法(压缩成型、注射成型、CAD-CAM 铣削和使用 3 种不同树脂在 3 种不同打印机上快速成型)制造丙烯酸树脂盘。使用 2 种不同的实验方法对每种材料的白僵菌粘附性进行了评估--悬浮在接种的胰蛋白酶大豆肉汤(TSB)中,或放置在含有 5% 羊血的胰蛋白胨大豆琼脂(TSA)上的白僵菌均匀草坪上。附着的细胞通过螺旋培养进行定量,然后用于重新接种无菌平板。对数据进行对数转换,使之标准化。对于肉汤悬浮液,使用 Kruskal-Wallis 检验来确定 6 种标本在回收率方面的差异,并使用 Dunn 检验进行事后分析。在微生物草坪实验中,采用了单因素方差分析(ANOVA)和 Tukey 诚实差异(HSD)事后检验:结果:根据生产方法和实验设计,粘附细胞数量之间存在统计学意义上的显著差异(PC 结论):尽管统计学意义显著,但两种实验技术都没有显示出任何特定树脂表面可能具有临床意义的优先结合性。附着的念珠菌细胞是未感染表面病原体的有效载体。需要进一步研究潜在的致病因素和印刷树脂的差异。
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引用次数: 0
Relationship between anterior occlusion, arch dimension, and mandibular movement during speech articulation: A three-dimensional analysis. 言语发音时前咬合、牙弓尺寸和下颌运动之间的关系:三维分析
IF 4.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-05 DOI: 10.1016/j.prosdent.2024.08.001
Taseef Hasan Farook, Lameesa Ramees, James Dudley

Statement of problem: Studies correlating occlusal morphology from 3-dimensional intraoral scans with both soft and hard tissue dynamic landmark tracking within the same participant population are lacking.

Purpose: The purpose of this clinical study was to use 3-dimensional intraoral scanning, computer-aided design, electrognathography, and artificial intelligence to investigate the relationships between anterior occlusion and arch parameters with hard and soft tissue displacements during speech production.

Material and methods: An artificial intelligence (AI) driven software program and electrognathography was used to record the phonetic activities in 62 participants for soft tissue (ST) and hard tissue (HT) displacement. Soft tissue displacement was quantified by the mean difference between subnasale and soft tissue pogonion peaks during phonetic expressions, and hard tissue displacement was directly measured with an electrognathograph. Intercanine and intermolar distances, arch perimeters, and horizontal and vertical overlap were measured from the intraoral scan data.

Results: ST and HT displacements were successfully estimated for fricative (ST=7.16 ±4.51 mm, HT=11.86 ±4.02 mm), sibilant (ST=5.11 ±3.49 mm, HT=8.24 ±3.31 mm), linguodental (ST=5.72 ±4.46 mm, HT=10.01 ±3.16 mm), and bilabial (ST=5.56 ±4.64 mm, HT=11.69 ±4.28 mm) phonetics. Vertical overlap correlated positively with hard tissue movement during all speech expressions except bilabial phonetics (ρ=.30 to.41, P<.05). Maxillary and mandibular arch perimeters showed negative correlations with soft tissue displacement during linguodental and bilabial speech (ρ=-.25 to -.41, P<.05) but were significantly correlated with hard tissue movement during all speech assessments (ρ=-.28 to -.44, P<.05). Maxillary intermolar distances negatively correlated with hard tissue phonetic expressions (ρ=-.24 to -.30, P<.05). Participant age positively correlated with soft tissue displacement during all speech patterns (ρ=.28 to.33, P<.05) and with weight increase (ρ=.27, P=.033), and hard tissue displacement (ρ=.25, P=.048) during maximum mouth opening significantly correlated with linguodental phonetics.

Conclusions: Within the study population, vertical overlap, maxillary intermolar distance, and dental arch perimeters correlated significantly with mandibular displacement during phonetic expression.

目的:本临床研究的目的是利用三维口内扫描、计算机辅助设计、电子注影术和人工智能技术,研究前咬合和牙弓参数与语言发音过程中软硬组织位移之间的关系:使用人工智能(AI)驱动的软件程序和电子显微镜记录了62名参与者的语音活动中的软组织(ST)和硬组织(HT)位移。软组织位移通过发音时鼻下峰与软组织峰之间的平均差来量化,而硬组织位移则通过电子显微镜直接测量。根据口内扫描数据测量了齿间距离、齿弓周长以及水平和垂直重叠度:结果:成功估算了摩擦音(ST=7.16 ±4.51 mm,HT=11.86 ±4.02 mm)、咝声(ST=5.11 ±3.49 mm,HT=8.24 ±3.31 mm)、舌齿音(ST=5.72 ±4.46 mm,HT=10.01 ±3.16 mm)和双唇音(ST=5.56 ±4.64 mm,HT=11.69 ±4.28 mm)的 ST 和 HT 位移。除双唇音外,垂直重叠与所有语音表达中的硬组织运动均呈正相关(ρ=.30 至.41,PC 结论:在研究人群中,垂直重叠度、上颌臼间距和牙弓周长与语音表达时的下颌骨位移有显著相关性。
{"title":"Relationship between anterior occlusion, arch dimension, and mandibular movement during speech articulation: A three-dimensional analysis.","authors":"Taseef Hasan Farook, Lameesa Ramees, James Dudley","doi":"10.1016/j.prosdent.2024.08.001","DOIUrl":"https://doi.org/10.1016/j.prosdent.2024.08.001","url":null,"abstract":"<p><strong>Statement of problem: </strong>Studies correlating occlusal morphology from 3-dimensional intraoral scans with both soft and hard tissue dynamic landmark tracking within the same participant population are lacking.</p><p><strong>Purpose: </strong>The purpose of this clinical study was to use 3-dimensional intraoral scanning, computer-aided design, electrognathography, and artificial intelligence to investigate the relationships between anterior occlusion and arch parameters with hard and soft tissue displacements during speech production.</p><p><strong>Material and methods: </strong>An artificial intelligence (AI) driven software program and electrognathography was used to record the phonetic activities in 62 participants for soft tissue (ST) and hard tissue (HT) displacement. Soft tissue displacement was quantified by the mean difference between subnasale and soft tissue pogonion peaks during phonetic expressions, and hard tissue displacement was directly measured with an electrognathograph. Intercanine and intermolar distances, arch perimeters, and horizontal and vertical overlap were measured from the intraoral scan data.</p><p><strong>Results: </strong>ST and HT displacements were successfully estimated for fricative (ST=7.16 ±4.51 mm, HT=11.86 ±4.02 mm), sibilant (ST=5.11 ±3.49 mm, HT=8.24 ±3.31 mm), linguodental (ST=5.72 ±4.46 mm, HT=10.01 ±3.16 mm), and bilabial (ST=5.56 ±4.64 mm, HT=11.69 ±4.28 mm) phonetics. Vertical overlap correlated positively with hard tissue movement during all speech expressions except bilabial phonetics (ρ=.30 to.41, P<.05). Maxillary and mandibular arch perimeters showed negative correlations with soft tissue displacement during linguodental and bilabial speech (ρ=-.25 to -.41, P<.05) but were significantly correlated with hard tissue movement during all speech assessments (ρ=-.28 to -.44, P<.05). Maxillary intermolar distances negatively correlated with hard tissue phonetic expressions (ρ=-.24 to -.30, P<.05). Participant age positively correlated with soft tissue displacement during all speech patterns (ρ=.28 to.33, P<.05) and with weight increase (ρ=.27, P=.033), and hard tissue displacement (ρ=.25, P=.048) during maximum mouth opening significantly correlated with linguodental phonetics.</p><p><strong>Conclusions: </strong>Within the study population, vertical overlap, maxillary intermolar distance, and dental arch perimeters correlated significantly with mandibular displacement during phonetic expression.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fixed prosthodontic rehabilitation using a facially driven fully digital workflow of a patient with syndromic amelogenesis imperfecta associated with a rare form of ectodermal dysplasia, tricho-dento-osseous (TDO) syndrome. 使用面部驱动的全数字化工作流程,对一名患有综合症的成骨不全症患者进行固定义齿修复,该综合症与一种罕见的外胚层发育不良(TDO)综合症有关。
IF 4.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-04 DOI: 10.1016/j.prosdent.2024.07.030
Naif Sinada, Christina I Wang

Tricho-dento-ossseous (TDO) syndrome is a rare form of ectodermal dysplasia (ED) characterized by defects in the hair, bones, nails, and teeth. Dental findings consistently seen in patients with TDO syndrome include amelogenesis imperfecta and taurodontism, but additional findings such as periapical abscesses, mandibular prognathism, and impacted teeth have been reported. Because of the rarity of this disorder, the prevalence is unknown and limited research is available regarding its dental management. This clinical report describes the fixed prosthodontic implant rehabilitation of an adult patient with TDO syndrome by using a facially driven fully digital workflow. The facially driven digital workflow streamlined the rehabilitation and allowed for functional, esthetic, and psychosocial improvements in a timely manner.

三趾趾骨发育不良(TDO)综合征是一种罕见的外胚层发育不良(ED),其特征是毛发、骨骼、指甲和牙齿存在缺陷。TDO综合征患者的牙齿症状通常包括成髓不全症和牙槽骨发育不全,但也有报道称患者会出现根尖周脓肿、下颌前突和阻生齿等其他症状。由于这种疾病的罕见性,其发病率尚不清楚,有关其牙科治疗的研究也很有限。本临床报告介绍了使用面部驱动全数字化工作流程对一名患有 TDO 综合征的成年患者进行固定义齿种植修复的情况。面部驱动的数字化工作流程简化了康复过程,及时改善了患者的功能、美观和社会心理。
{"title":"Fixed prosthodontic rehabilitation using a facially driven fully digital workflow of a patient with syndromic amelogenesis imperfecta associated with a rare form of ectodermal dysplasia, tricho-dento-osseous (TDO) syndrome.","authors":"Naif Sinada, Christina I Wang","doi":"10.1016/j.prosdent.2024.07.030","DOIUrl":"https://doi.org/10.1016/j.prosdent.2024.07.030","url":null,"abstract":"<p><p>Tricho-dento-ossseous (TDO) syndrome is a rare form of ectodermal dysplasia (ED) characterized by defects in the hair, bones, nails, and teeth. Dental findings consistently seen in patients with TDO syndrome include amelogenesis imperfecta and taurodontism, but additional findings such as periapical abscesses, mandibular prognathism, and impacted teeth have been reported. Because of the rarity of this disorder, the prevalence is unknown and limited research is available regarding its dental management. This clinical report describes the fixed prosthodontic implant rehabilitation of an adult patient with TDO syndrome by using a facially driven fully digital workflow. The facially driven digital workflow streamlined the rehabilitation and allowed for functional, esthetic, and psychosocial improvements in a timely manner.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of adding graphene fibers to polymethyl methacrylate on biocompatibility and surface characterization. 在聚甲基丙烯酸甲酯中添加石墨烯纤维对生物相容性和表面特性的影响。
IF 4.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-03 DOI: 10.1016/j.prosdent.2024.07.043
Ildefonso Serrano-Belmonte, Francisco Javier Cascales-Pérez, Virginia Pérez-Fernández, Ascensión Martínez-Cánovas, María Rosario Tudela-Mulero, Juan Ignacio Rosales-Leal

Statement of problem: Interim fixed prostheses are used provisionally to provide esthetics and maintain function until placement of the definitive prosthesis. Polymethyl methacrylate (PMMA) has been widely used as an interim material but has mechanical limitations that can be improved with the addition of nanomaterials such as graphene fibers (PMMA-G). However, studies on the biocompatibility of this material are lacking.

Purpose: The purpose of this in vitro study was to determine the biocompatibility and cytotoxic effects of PMMA compared with PMMA-G in periodontal ligament stem cells (PDLSCs) by measuring the viability and cell apoptosis of those cells subjected to different concentrations of both compounds by elution, as well as the surface characterization of these materials.

Material and methods: Sterile Ø20×15-mm specimens of PMMA and PMMA-G were covered with Dulbecco modified Eagle medium for 24 hours to be the subsequent eluent. PDLSCs were seeded in 6 plates of 96 wells at dilutions 1/1, 1/2, 1/4, and 1/8 for each material. Three plates for the cell viability assay with MTT and 3 plates for the cell apoptosis assay with Hoechst 33342 staining were used in turn to subdivide the measurements at 24, 48, and 72 hours. The Kruskal-Wallis test was used to compare the data obtained in the different dilutions at different times and the Mann-Whitney test to compare both materials. Topography and wetting were analyzed for surface characterization. The Student t test of paired measurements was used to compare the different surfaces for each parameter (α=.05 for all tests).

Results: In both the cell viability assay (MTT) and the cell apoptosis assay, the test did not identify statistically significant differences in PMMA and PMMA-G with respect to the control group in the different dilutions at different times (P>.05). When comparing both materials, no statistically significant differences (P=.268) were found in either trial. PMMA-G had lower roughness and kurtosis and higher wetting than PMMA.

Conclusions: Both PMMA and PMMA-G were found to be biocompatible materials with no significant differences between them after cell viability and apoptosis testing. PMMA-G had higher wettability and lower roughness than PMMA.

问题简介:临时固定义齿用于在安装最终义齿之前提供美观和维持功能。聚甲基丙烯酸甲酯(PMMA)已被广泛用作临时材料,但其机械性能有限,添加石墨烯纤维(PMMA-G)等纳米材料后可改善机械性能。目的:本体外研究的目的是通过洗脱法测量不同浓度两种化合物作用下牙周韧带干细胞(PDLSCs)的存活率和细胞凋亡情况,以及这些材料的表面特征,从而确定 PMMA 与 PMMA-G 对牙周韧带干细胞(PDLSCs)的生物相容性和细胞毒性作用:无菌的 Ø20×15 mm PMMA 和 PMMA-G 试样用 Dulbecco 改良鹰培养基覆盖 24 小时,作为后续洗脱液。将 PDLSCs 按每种材料 1/1、1/2、1/4 和 1/8 的稀释度种于 6 个 96 孔板中。在 24、48 和 72 小时内,依次用 3 个平板进行 MTT 细胞活力检测,用 3 个平板进行 Hoechst 33342 染色细胞凋亡检测。使用 Kruskal-Wallis 检验比较不同稀释液在不同时间获得的数据,使用 Mann-Whitney 检验比较两种材料。对地形和润湿进行了分析,以确定表面特征。采用配对测量的学生 t 检验来比较不同表面的各项参数(所有检验均采用 α=.05):在细胞存活率检测(MTT)和细胞凋亡检测中,均未发现 PMMA 和 PMMA-G 与对照组在不同稀释度、不同时间的差异有统计学意义(P>.05)。在比较两种材料时,均未发现有统计学意义的差异(P=.268)。与 PMMA 相比,PMMA-G 的粗糙度和峰度较低,湿润度较高:结论:PMMA 和 PMMA-G 都是生物相容性材料,在细胞存活率和细胞凋亡测试后,两者之间没有明显差异。与 PMMA 相比,PMMA-G 具有更高的润湿性和更低的粗糙度。
{"title":"Effects of adding graphene fibers to polymethyl methacrylate on biocompatibility and surface characterization.","authors":"Ildefonso Serrano-Belmonte, Francisco Javier Cascales-Pérez, Virginia Pérez-Fernández, Ascensión Martínez-Cánovas, María Rosario Tudela-Mulero, Juan Ignacio Rosales-Leal","doi":"10.1016/j.prosdent.2024.07.043","DOIUrl":"https://doi.org/10.1016/j.prosdent.2024.07.043","url":null,"abstract":"<p><strong>Statement of problem: </strong>Interim fixed prostheses are used provisionally to provide esthetics and maintain function until placement of the definitive prosthesis. Polymethyl methacrylate (PMMA) has been widely used as an interim material but has mechanical limitations that can be improved with the addition of nanomaterials such as graphene fibers (PMMA-G). However, studies on the biocompatibility of this material are lacking.</p><p><strong>Purpose: </strong>The purpose of this in vitro study was to determine the biocompatibility and cytotoxic effects of PMMA compared with PMMA-G in periodontal ligament stem cells (PDLSCs) by measuring the viability and cell apoptosis of those cells subjected to different concentrations of both compounds by elution, as well as the surface characterization of these materials.</p><p><strong>Material and methods: </strong>Sterile Ø20×15-mm specimens of PMMA and PMMA-G were covered with Dulbecco modified Eagle medium for 24 hours to be the subsequent eluent. PDLSCs were seeded in 6 plates of 96 wells at dilutions 1/1, 1/2, 1/4, and 1/8 for each material. Three plates for the cell viability assay with MTT and 3 plates for the cell apoptosis assay with Hoechst 33342 staining were used in turn to subdivide the measurements at 24, 48, and 72 hours. The Kruskal-Wallis test was used to compare the data obtained in the different dilutions at different times and the Mann-Whitney test to compare both materials. Topography and wetting were analyzed for surface characterization. The Student t test of paired measurements was used to compare the different surfaces for each parameter (α=.05 for all tests).</p><p><strong>Results: </strong>In both the cell viability assay (MTT) and the cell apoptosis assay, the test did not identify statistically significant differences in PMMA and PMMA-G with respect to the control group in the different dilutions at different times (P>.05). When comparing both materials, no statistically significant differences (P=.268) were found in either trial. PMMA-G had lower roughness and kurtosis and higher wetting than PMMA.</p><p><strong>Conclusions: </strong>Both PMMA and PMMA-G were found to be biocompatible materials with no significant differences between them after cell viability and apoptosis testing. PMMA-G had higher wettability and lower roughness than PMMA.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanical properties of dual-polymerizing resin-core material, dual-polymerizing resin cement, and bulk-fill composite resin used for restoring endodontically treated teeth. 用于修复根管治疗牙齿的双聚合树脂芯材料、双聚合树脂粘合剂和大量填充复合树脂的机械性能。
IF 4.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-02 DOI: 10.1016/j.prosdent.2024.08.007
Lilibeth Carola Leyton Mendoza, Thiago Silva Peres, Isaac Daniel Gonzaga Estevão, Maria Tereza Hordones Ribeiro, Calebe de Melo, Hugo Lemes Carlos, Carlos José Soares

Statement of problem: How resin-based material and a light-activation protocol influence the mechanical properties of materials used to cement glass fiber post-and-cores in endodontically treated teeth is unclear.

Purpose: The purpose of this in vitro study was to evaluate the influence of immediate or 5-minute delayed light activation on the mechanical properties of dual-polymerizing resin cements and dual-polymerizing resin-core materials compared with bulk-fill composite resins.

Material and methods: Nine resin-based materials were tested: 4 dual-polymerizing resin-core materials, (Allcem Core; FGM, LuxaCore Z; DMG, Rebilda DC; VOCO, and (Clearfil DC Core Plus; KURARAY), 3 dual-polymerizing resin cements, (RelyX Universal; 3M ESPE, RelyX U200; 3M ESPE, and Allcem Dual; FGM), and 2 bulk-fill composite resins, (Opus Bulk Fill APS; FGM, and Filtek One Bulk Fill; 3M ESPE). The dual-polymerizing materials were light activated using both protocols. The postgel shrinkage (Shr), flexural strength (FS), elastic modulus (E), Knoop hardness (KH), degree of conversion (DC), and depth of polymerization (DoP) were measured (n=10). The data for Shr, FS, E, and DoP were analyzed using 2-way ANOVA, and for KH and DC using 2-way repeated measurement ANOVA and the Tukey HSD test (α=.05).

Results: A 5-minute delay before light-activation significantly reduced Shr for all materials (P<.001). Increasing the depth significantly reduced the KH for all materials (P<.001). Bulk-fill composite resins and dual-polymerizing resin-core had higher KH values than dual-polymerizing resin cements (P<.001).

Conclusions: Delayed 5-minute light-activation reduced postgel shrinkage and had no negative effect on mechanical properties. Dual-polymerizing resin-core materials exhibited higher KH values than dual-polymerizing resin cement and mechanical properties similar to those of bulk-fill composite resin.

问题陈述:目前还不清楚树脂基材料和光激活方案如何影响牙髓治疗牙玻璃纤维桩核粘结材料的机械性能。目的:本体外研究的目的是评估即刻或延迟 5 分钟光激活对双聚合树脂粘结剂和双聚合树脂桩核材料机械性能的影响,并与大量填充的复合树脂进行比较:对九种树脂材料进行了测试:4 种双聚合树脂芯材(Allcem Core;FGM、LuxaCore Z;DMG、Rebilda DC;VOCO 和(Clearfil DC Core Plus;KURARAY))、3 种双聚合树脂水门汀(RelyX Universal;3M ESPE、RelyX U200;3M ESPE 和 Allcem Dual;FGM)和 2 种大量填充复合树脂(Opus Bulk Fill APS;FGM 和 Filtek One Bulk Fill;3M ESPE)。双聚合材料采用两种方案进行光激活。测量了凝胶后收缩率 (Shr)、抗弯强度 (FS)、弹性模量 (E)、努氏硬度 (KH)、转化率 (DC) 和聚合深度 (DoP)(n=10)。对 Shr、FS、E 和 DoP 的数据采用双向方差分析,对 KH 和 DC 的数据采用双向重复测量方差分析和 Tukey HSD 检验(α=.05):结果:光激活前延迟 5 分钟可显著降低所有材料的 Shr 值(PC 结论:光激活前延迟 5 分钟可显著降低所有材料的 Shr 值:延迟 5 分钟光激活可减少凝胶后收缩,对机械性能没有负面影响。双聚合树脂牙髓材料的 KH 值高于双聚合树脂水泥,机械性能与大量填充复合树脂相似。
{"title":"Mechanical properties of dual-polymerizing resin-core material, dual-polymerizing resin cement, and bulk-fill composite resin used for restoring endodontically treated teeth.","authors":"Lilibeth Carola Leyton Mendoza, Thiago Silva Peres, Isaac Daniel Gonzaga Estevão, Maria Tereza Hordones Ribeiro, Calebe de Melo, Hugo Lemes Carlos, Carlos José Soares","doi":"10.1016/j.prosdent.2024.08.007","DOIUrl":"https://doi.org/10.1016/j.prosdent.2024.08.007","url":null,"abstract":"<p><strong>Statement of problem: </strong>How resin-based material and a light-activation protocol influence the mechanical properties of materials used to cement glass fiber post-and-cores in endodontically treated teeth is unclear.</p><p><strong>Purpose: </strong>The purpose of this in vitro study was to evaluate the influence of immediate or 5-minute delayed light activation on the mechanical properties of dual-polymerizing resin cements and dual-polymerizing resin-core materials compared with bulk-fill composite resins.</p><p><strong>Material and methods: </strong>Nine resin-based materials were tested: 4 dual-polymerizing resin-core materials, (Allcem Core; FGM, LuxaCore Z; DMG, Rebilda DC; VOCO, and (Clearfil DC Core Plus; KURARAY), 3 dual-polymerizing resin cements, (RelyX Universal; 3M ESPE, RelyX U200; 3M ESPE, and Allcem Dual; FGM), and 2 bulk-fill composite resins, (Opus Bulk Fill APS; FGM, and Filtek One Bulk Fill; 3M ESPE). The dual-polymerizing materials were light activated using both protocols. The postgel shrinkage (Shr), flexural strength (FS), elastic modulus (E), Knoop hardness (KH), degree of conversion (DC), and depth of polymerization (DoP) were measured (n=10). The data for Shr, FS, E, and DoP were analyzed using 2-way ANOVA, and for KH and DC using 2-way repeated measurement ANOVA and the Tukey HSD test (α=.05).</p><p><strong>Results: </strong>A 5-minute delay before light-activation significantly reduced Shr for all materials (P<.001). Increasing the depth significantly reduced the KH for all materials (P<.001). Bulk-fill composite resins and dual-polymerizing resin-core had higher KH values than dual-polymerizing resin cements (P<.001).</p><p><strong>Conclusions: </strong>Delayed 5-minute light-activation reduced postgel shrinkage and had no negative effect on mechanical properties. Dual-polymerizing resin-core materials exhibited higher KH values than dual-polymerizing resin cement and mechanical properties similar to those of bulk-fill composite resin.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the biomechanics of Aramany class I obturators of different designs using numerical and experimental methods. Part II: Stress distribution. 使用数值和实验方法评估不同设计的 Aramany I 类闭锁器的生物力学。第二部分:应力分布。
IF 4.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-02 DOI: 10.1016/j.prosdent.2024.07.042
Mohammed A Mousa, Adam Husein, Mohamed I El-Anwar, Azirrawani Ariffin, Johari Yap Abdullah

Statement of problem: Evidence regarding stress evaluations of removable obturators with Aramany class I defects is lacking. Whether the stress distribution on Aramany class I prostheses can be improved by modifying the currently used designs is also unclear.

Purpose: The purpose of part II of this study was to evaluate the stress distribution in different designs of Aramany class I obturators using finite element analysis (FEA) and photoelastic stress analysis.

Material and methods: Four finite element and 8 photoelastic models, including 2 acrylic resin base obturators retained with 2 Adams clasps, 2 linear, 2 tripodal, and 2 fully tripodal design obturators, were used in this study. The frameworks were fabricated on the casts obtained from a modified printed model. Vertical and oblique loads were applied on 2 points (anterior and posterior) of the models. The quantitative measurement was done by measuring the fringe orders and von Mises values to compare the influences of occlusal forces on the obturator components and their supporting structures. The qualitative evaluation was done by visual color mapping to identify the stress concentration.

Results: In the photoelastic analysis, the anterior abutments of the tripodal showed the highest stress, followed by the fully tripodal obturators, while, in FEA, the anterior abutments of the linear design received the most in both vertical and oblique load. The central incisor received the most stress in photoelastic (3 or more fringe orders) and FEA (687.3 and 150.1 MPa for vertical and oblique loads, respectively), followed by the lateral incisors. Upon posterior loading, the base of the defect of the linear design demonstrated the most stress in photoelastic (3 or more fringes) and FEA (94.3 and 130.5 MPa for vertical and oblique loads, respectively). The acrylic resin base obturator retained with Adams clasps demonstrated the lowest stress distribution in abutments and their supporting bone upon anterior and posterior loads.

Conclusions: Upon vertical and oblique load application, the fully tripodal design was comparable with the tripodal in terms of stress distribution. Both designs were better than the linear in response to the same loading. The stress was concentrated at the anterior palatal part of the obturator, the base of the defect, and the junction of the metal and acrylic resin part of the prostheses upon anterior and posterior loading, respectively.

问题陈述:目前尚缺乏对具有Aramany I类缺陷的可摘义齿进行应力评估的证据。目的:本研究第二部分的目的是使用有限元分析(FEA)和光弹性应力分析来评估不同设计的 Aramany I 类闭锁器的应力分布:本研究使用了 4 个有限元模型和 8 个光弹性模型,包括 2 个丙烯酸树脂基底闭锁器,2 个亚当斯扣,2 个线性闭锁器,2 个三脚架设计闭锁器和 2 个完全三脚架设计闭锁器。骨架是在改良打印模型的铸模上制作的。对模型的两个点(前部和后部)施加垂直和倾斜负荷。定量测量是通过测量边缘阶数和 von Mises 值来比较咬合力对闭锁器部件及其支撑结构的影响。定性评估则是通过视觉颜色图来识别应力集中:在光弹性分析中,三足式前基台的应力最大,其次是全三足式闭锁器,而在有限元分析中,线性设计的前基台受到的垂直和倾斜负荷最大。在光弹性(3 个或更多边缘阶)和有限元分析中,中切牙受到的应力最大(垂直和倾斜负荷分别为 687.3 和 150.1 兆帕),其次是侧切牙。在后方加载时,线性设计的缺损基底在光弹性(3 个或更多条纹)和有限元分析(垂直和倾斜加载时分别为 94.3 和 130.5 兆帕)中显示出最大的应力。用亚当斯卡环固位的丙烯酸树脂基台在承受前后负荷时,基台及其支持骨的应力分布最小:在承受垂直和斜向负荷时,全三叉设计与三叉设计的应力分布相当。在相同负荷下,两种设计都优于线性设计。在前方和后方加载时,应力分别集中在闭锁器的前腭部分、缺损基底以及修复体的金属部分和丙烯酸树脂部分的交界处。
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引用次数: 0
Anatomic CAD-CAM post-and-core systems: A mastication simulation study 解剖学 CAD-CAM 后牙髓系统:咀嚼模拟研究
IF 4.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-01 DOI: 10.1016/j.prosdent.2022.08.017

Statement of problem

Few studies have investigated the differences among various post-and-core systems under mastication simulation. Comparing these systems while simulating the clinical environment should provide a more accurate assessment of their performance.

Purpose

The purpose of this in vitro study was to evaluate the fatigue resistance of conventional cast metal and prefabricated fiber post systems with computer-aided design and computer-aided manufacture (CAD-CAM) prefabricated nonmetal post-and-core systems.

Material and methods

Forty freshly extracted human maxillary premolars were endodontically treated and divided into 4 subgroups (n=10) according to the material: cast metal, zirconia, fiber-reinforced composite resin, prefabricated fiber post. The post-and-core materials were manufactured either conventionally or milled with CAD-CAM technology. All specimens were exposed to simultaneous mastication simulation (1.2 million cycles) and thermocycling (10 000 cycles at 5 °C to 55 °C) and analyzed based on failure of specimens. Data were analyzed by using the Kaplan-Meier survival analysis and Cox-regression (α=.05).

Results

Both cast metal and zirconia post-and-core groups had similar fatigue resistance (P>.05) but significantly higher fatigue resistance than the fiber-reinforced groups (P<.05). Fiber-reinforced composite resin and prefabricated fiber post did not survive the mastication simulation, fracturing between 504 000 and 752 000 cycles, with fractures occurring in the cervical portion of the tooth.

Conclusions

Cast metal and zirconia post-and-core systems had improved physical properties with high resistance to fatigue when compared with fiber-reinforced post-and-core systems.

问题陈述:很少有研究调查过在咀嚼模拟下各种桩核系统之间的差异。目的:这项体外研究的目的是评估传统铸造金属和预制纤维桩系统与计算机辅助设计和计算机辅助制造(CAD-CAM)预制非金属桩核系统的抗疲劳性:对40颗新鲜拔出的人类上颌前磨牙进行根管治疗,并根据材料分为4个亚组(n=10):铸造金属、氧化锆、纤维增强复合树脂、预制纤维桩。桩核材料有传统制造的,也有使用 CAD-CAM 技术铣制的。所有试样均同时暴露于模拟咀嚼(120 万次)和热循环(10 000 次,温度为 5 °C 至 55 °C),并根据试样的失效情况进行分析。数据分析采用 Kaplan-Meier 生存分析和 Cox 回归(α=.05):结果:铸造金属组和氧化锆后加芯组的抗疲劳性相似(P>.05),但明显高于纤维增强组(PC结论:铸造金属组和氧化锆后加芯组的抗疲劳性相似,但明显高于纤维增强组(P>.05):铸造金属和氧化锆后和心系统与纤维增强后和心系统相比,具有更好的物理性能和更高的抗疲劳性。
{"title":"Anatomic CAD-CAM post-and-core systems: A mastication simulation study","authors":"","doi":"10.1016/j.prosdent.2022.08.017","DOIUrl":"10.1016/j.prosdent.2022.08.017","url":null,"abstract":"<div><h3>Statement of problem</h3><p>Few studies have investigated the differences among various post-and-core systems under mastication simulation. Comparing these systems while simulating the clinical environment should provide a more accurate assessment of their performance.</p></div><div><h3>Purpose</h3><p>The purpose of this in vitro study was to evaluate the fatigue resistance of conventional cast metal and prefabricated fiber post systems with computer-aided design and computer-aided manufacture (CAD-CAM) prefabricated nonmetal post-and-core systems.</p></div><div><h3>Material and methods</h3><p>Forty freshly extracted human maxillary premolars<span> were endodontically treated and divided into 4 subgroups (n=10) according to the material: cast metal, zirconia, fiber-reinforced composite resin, prefabricated fiber post. The post-and-core materials were manufactured either conventionally or milled with CAD-CAM technology. All specimens were exposed to simultaneous mastication simulation (1.2 million cycles) and thermocycling (10 000 cycles at 5 °C to 55 °C) and analyzed based on failure of specimens. Data were analyzed by using the Kaplan-Meier survival analysis and Cox-regression (α=.05).</span></p></div><div><h3>Results</h3><p>Both cast metal and zirconia post-and-core groups had similar fatigue resistance (<em>P</em>&gt;.05) but significantly higher fatigue resistance than the fiber-reinforced groups (<em>P</em>&lt;.05). Fiber-reinforced composite resin and prefabricated fiber post did not survive the mastication simulation, fracturing between 504 000 and 752 000 cycles, with fractures occurring in the cervical portion of the tooth.</p></div><div><h3>Conclusions</h3><p>Cast metal and zirconia post-and-core systems had improved physical properties with high resistance to fatigue when compared with fiber-reinforced post-and-core systems.</p></div>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40376036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Prosthetic Dentistry
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