Pub Date : 2023-11-27DOI: 10.18502/ssu.v31i9.14182
Mohsen Mohammadgholi, Fatemeh Pourbahman
Introduction: After the outbreak of the Coronavirus and the epidemic of its attributed disease worldwide, many scientists decided to use new strategies to diagnose, prevent and treat the coronavirus-caused disease. Nanotechnology, with a wide range of applications in various sciences, including medicine, helps to progress and solve many of its problems. Nanosystems with unique features have a special place in drug delivery and biomolecule transport. They can transfer antiviral and other drugs that face the coronavirus through different mechanisms in the blood plasma and between cells. Likewise, viral components and antibodies against them are moved between cellular and subcellular boundaries by some of these systems. Conclusion: This study investigated the application of nanosystems in targeted drug delivery, vaccination, and diagnosis of corona disease.
{"title":"Targeted Strategies Against Coronavirus Using Nanotechnology","authors":"Mohsen Mohammadgholi, Fatemeh Pourbahman","doi":"10.18502/ssu.v31i9.14182","DOIUrl":"https://doi.org/10.18502/ssu.v31i9.14182","url":null,"abstract":"Introduction: After the outbreak of the Coronavirus and the epidemic of its attributed disease worldwide, many scientists decided to use new strategies to diagnose, prevent and treat the coronavirus-caused disease. Nanotechnology, with a wide range of applications in various sciences, including medicine, helps to progress and solve many of its problems. Nanosystems with unique features have a special place in drug delivery and biomolecule transport. They can transfer antiviral and other drugs that face the coronavirus through different mechanisms in the blood plasma and between cells. Likewise, viral components and antibodies against them are moved between cellular and subcellular boundaries by some of these systems. Conclusion: This study investigated the application of nanosystems in targeted drug delivery, vaccination, and diagnosis of corona disease.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139234790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18502/ssu.v31i9.14189
Habibollah Zare, A. Astani, Mina Golban, Mahmood Vakili, A. Mosadegh
Introduction: Bacteriocins are peptides with antimicrobial properties. They are ribosomally synthesized and produced by both gram-positive and gram-negative bacteria. The bacteriocins produced by Escherichia coli are called colicins. Colicins in commensal bacteria inhibit the growth of pathogenic bacteria and in pathogen strains, they increase bacterial virulence. The aim of this study was to evaluate the frequency of col V and col Ia genes in Escherichia coli specimens isolated from patients with urinary tract infections in Yazd City, Iran. Methods: In this descriptive cross-sectional study, 160 Escherichia coli samples were isolated from urine specimens and identified by common biochemical tests. The amplification of col V and col Ia genes was performed by PCR method using specific primers and after sequencing, the results were analyzed using SPSS version 16 software. Results: In this study, out of 160 Escherichia coli isolates examined, calicin gene was detected in 26.9% of the isolates. The frequency of col Ia gene was 24.4% and the frequency of col V gene was 10.6%. Furthermore, in 8.12% of isolates, both genes were identified together. The frequency of isolates containing only col Ia gene was 16.2% and isolates containing only col V gene was 2.5%. Conclusion: In this study, isolates with col Ia gene showed high frequency. Most strains with col V gene also had col Ia gene. Therefore, the col V gene is often observed together with the col Ia gene.
引言细菌素是一种具有抗菌特性的多肽。它们由核糖体合成，由革兰氏阳性和革兰氏阴性细菌产生。大肠杆菌产生的细菌素被称为大肠杆菌素。肠毒素在共生菌中可抑制病原菌的生长，而在病原菌中则可增强细菌的毒力。本研究的目的是评估从伊朗亚兹德市尿路感染患者体内分离出的大肠埃希菌标本中 col V 和 col Ia 基因的频率。 研究方法在这项描述性横断面研究中，从尿液标本中分离出 160 份大肠埃希菌样本，并通过普通生化检验进行鉴定。使用特定引物通过 PCR 方法扩增 col V 和 col Ia 基因，测序后使用 SPSS 16 版软件对结果进行分析。 结果本研究检测了 160 株大肠埃希菌分离物，其中 26.9%的分离物检测到钙霉素基因。col Ia 基因的频率为 24.4%，col V 基因的频率为 10.6%。此外，在 8.12%的分离物中，两种基因同时被鉴定出来。仅含有 col Ia 基因的分离物频率为 16.2%，仅含有 col V 基因的分离物频率为 2.5%。 结论在这项研究中，含有 col Ia 基因的分离株出现频率较高。大多数含有 col V 基因的菌株也含有 col Ia 基因。因此，col V 基因经常与 col Ia 基因同时出现。
{"title":"Determining the Frequency of Genes Producing Colicins Ia and V in Escherichia coli Strains Isolated from Clinical Samples of Medical Centers in Yazd City","authors":"Habibollah Zare, A. Astani, Mina Golban, Mahmood Vakili, A. Mosadegh","doi":"10.18502/ssu.v31i9.14189","DOIUrl":"https://doi.org/10.18502/ssu.v31i9.14189","url":null,"abstract":"Introduction: Bacteriocins are peptides with antimicrobial properties. They are ribosomally synthesized and produced by both gram-positive and gram-negative bacteria. The bacteriocins produced by Escherichia coli are called colicins. Colicins in commensal bacteria inhibit the growth of pathogenic bacteria and in pathogen strains, they increase bacterial virulence. The aim of this study was to evaluate the frequency of col V and col Ia genes in Escherichia coli specimens isolated from patients with urinary tract infections in Yazd City, Iran. Methods: In this descriptive cross-sectional study, 160 Escherichia coli samples were isolated from urine specimens and identified by common biochemical tests. The amplification of col V and col Ia genes was performed by PCR method using specific primers and after sequencing, the results were analyzed using SPSS version 16 software. Results: In this study, out of 160 Escherichia coli isolates examined, calicin gene was detected in 26.9% of the isolates. The frequency of col Ia gene was 24.4% and the frequency of col V gene was 10.6%. Furthermore, in 8.12% of isolates, both genes were identified together. The frequency of isolates containing only col Ia gene was 16.2% and isolates containing only col V gene was 2.5%. Conclusion: In this study, isolates with col Ia gene showed high frequency. Most strains with col V gene also had col Ia gene. Therefore, the col V gene is often observed together with the col Ia gene.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139228102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18502/ssu.v31i9.14184
S. H. Razavi, Dorsa Pourzarabi, Mahjube Entezar-e-ghaem, Nasim Namiranian, Yaser Safi, Mohammad Pourmohammadi
Introduction: Canalis Sinuosus (CS) is a bony canal in the upper jaw. This canal has branches towards the anterior ridge and the teeth, which can be exposed to damage during dental procedures such as implants, resulting in paranesthesia. The purpose of this study was to determine the frequency of CS in the anterior region of the maxilla by CBCT radiography in a private radiology center in Yazd City in the last 2 years, to familiarize dentists with this anatomical variety and prevent complications. Methods: In this cross-sectional study, 218 CBCT images were selected. Images are related to the patients in the age range of 24 to 80 years. Axial, coronal and sagittal sections are reconstructed by an oral and maxillofacial radiologist. The images reviewed by two radiologists. Then, age, sex, frequency, location of the canal ending, bilateral or unilateral, sub-branches and the location of the canal in the vertical and anteroposterior dimension were checked. The results were investigated by SPSS version 16 software with Chi squared and T-test statistical tests. Results: The reviewed images belonged to 112 (51.4%) women and 106 (48.6%) men. The frequency of CS was 96.3%. The most frequency was found in women in the age of 24-44 years (62.8%). The 95.4% was reported bilaterally. In the examination of the Accessory canals, they were not seen in 141 people (64.7%). The accessory canal (AC) was reported more frequent between central and lateral incisor. In this study, using the Chi-Square test, there was no statistically significant relationship between the presence of CS and age (P=0.188) and gender (P=0.162). Conclusion: Due to the high frequency of CS and its branches in the anterior region of the maxilla, in order to avoid unwanted consequences during surgery, the desired area should be examined.
{"title":"Frequency of Canalis Sinuosus Canal in the Anterior Region of the Maxilla by CBCT Radiography in Patients Referred to a Private Radiology Center in the Last 2 Years in Yazd City","authors":"S. H. Razavi, Dorsa Pourzarabi, Mahjube Entezar-e-ghaem, Nasim Namiranian, Yaser Safi, Mohammad Pourmohammadi","doi":"10.18502/ssu.v31i9.14184","DOIUrl":"https://doi.org/10.18502/ssu.v31i9.14184","url":null,"abstract":"Introduction: Canalis Sinuosus (CS) is a bony canal in the upper jaw. This canal has branches towards the anterior ridge and the teeth, which can be exposed to damage during dental procedures such as implants, resulting in paranesthesia. The purpose of this study was to determine the frequency of CS in the anterior region of the maxilla by CBCT radiography in a private radiology center in Yazd City in the last 2 years, to familiarize dentists with this anatomical variety and prevent complications. Methods: In this cross-sectional study, 218 CBCT images were selected. Images are related to the patients in the age range of 24 to 80 years. Axial, coronal and sagittal sections are reconstructed by an oral and maxillofacial radiologist. The images reviewed by two radiologists. Then, age, sex, frequency, location of the canal ending, bilateral or unilateral, sub-branches and the location of the canal in the vertical and anteroposterior dimension were checked. The results were investigated by SPSS version 16 software with Chi squared and T-test statistical tests. Results: The reviewed images belonged to 112 (51.4%) women and 106 (48.6%) men. The frequency of CS was 96.3%. The most frequency was found in women in the age of 24-44 years (62.8%). The 95.4% was reported bilaterally. In the examination of the Accessory canals, they were not seen in 141 people (64.7%). The accessory canal (AC) was reported more frequent between central and lateral incisor. In this study, using the Chi-Square test, there was no statistically significant relationship between the presence of CS and age (P=0.188) and gender (P=0.162). Conclusion: Due to the high frequency of CS and its branches in the anterior region of the maxilla, in order to avoid unwanted consequences during surgery, the desired area should be examined.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139231832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18502/ssu.v31i9.14183
Mohsen Barzegar, Sara Tajali, A. Pouyafard
Introduction: Treatment of head and neck cancers, it can have adverse effects on patients' oral health status. The aim of this study was to assess the level of knowledge and practice of general dentists in Yazd City in the field of oral care in patients undergoing chemotherapy and radiotherapy. Methods: In this descriptive cross-sectional study, 134 general dentists were selected by systematic random sampling and their awareness and practice level were assessed using by using a researcher-made questionnaire with valid and reliable questionnaire (r=0.81). Data were analyzed using SPSS software version 25, t-test and ANOVA tests. Results: The mean score of knowledge score was 11.44 ±2.03 out of18 and mean of practice score was11.9 ±3.41 out OF 20. The mean score of knowledge was not significantly associated with age, work experience and practice score were not significantly associated with gender, age and work experience, but the mean score of knowledge in women was significantly higher than men (P=0.01). Moreover, dentists worked in both clinic and Personal office showed significantly higher awareness (P=0.001). The average practice score of dentists in personal office was significantly higher than other options (P=0.03). Conclusion: Dentists of Yazd had moderate knowledge and performance level in the field of oral and dental care in patients undergoing chemotherapy and radiotherapy. It seems that the need to hold programs with this theme in the sessions of continuing education and holding training and educational webinar to improve the level of awareness and clinical practice to provide desirable services to these patients should be considered.
{"title":"Assessment of the Knowledge and Practice of General Dentists in Yazd City about Oral and Dental Care of Patients Undergoing Radiotherapy and Chemotherapy in 2021-2022","authors":"Mohsen Barzegar, Sara Tajali, A. Pouyafard","doi":"10.18502/ssu.v31i9.14183","DOIUrl":"https://doi.org/10.18502/ssu.v31i9.14183","url":null,"abstract":"Introduction: Treatment of head and neck cancers, it can have adverse effects on patients' oral health status. The aim of this study was to assess the level of knowledge and practice of general dentists in Yazd City in the field of oral care in patients undergoing chemotherapy and radiotherapy. Methods: In this descriptive cross-sectional study, 134 general dentists were selected by systematic random sampling and their awareness and practice level were assessed using by using a researcher-made questionnaire with valid and reliable questionnaire (r=0.81). Data were analyzed using SPSS software version 25, t-test and ANOVA tests. Results: The mean score of knowledge score was 11.44 ±2.03 out of18 and mean of practice score was11.9 ±3.41 out OF 20. The mean score of knowledge was not significantly associated with age, work experience and practice score were not significantly associated with gender, age and work experience, but the mean score of knowledge in women was significantly higher than men (P=0.01). Moreover, dentists worked in both clinic and Personal office showed significantly higher awareness (P=0.001). The average practice score of dentists in personal office was significantly higher than other options (P=0.03). Conclusion: Dentists of Yazd had moderate knowledge and performance level in the field of oral and dental care in patients undergoing chemotherapy and radiotherapy. It seems that the need to hold programs with this theme in the sessions of continuing education and holding training and educational webinar to improve the level of awareness and clinical practice to provide desirable services to these patients should be considered.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139232220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18502/ssu.v31i9.14186
Fatemeh Bandegani, G. Afzal, Mehrnoush Dianatkhah, S. Sohrevardi
Introduction: The rational use of drugs is one of the main elements of achieving the best pharmacotherapy method for patients. Linezolid is used for infections caused by gram-positive bacteria, including vancomycin-resistant staphylococci and vancomycin-resistant enterococci, but the inappropriate use of this drug has led to the emergence of linezolid-resistant strains. The purpose of this study was to investigate the manner of Linezolid prescription in Shahid Chamran Hospital of Isfahan City in 2021. Methods: This cross sectional study was conducted during a period of 6 months (From September 1, 2021 to February 31, 2022) on 102 patients admitted to Shahid Chamran Hospital in Isfahan City. Patient information such as demographic information, indication and dosages of drugs, the basis of drug prescription, side effects and drug interactions, etc. were extracted from the medical records of patients and hospital systems and recorded in designed forms. After matching the information with the relevant guidelines, statistical analysis was performed using SPSS-16 software. Results: Out of the 102 patients, who received linezolid, 75.1% were men and the rest were women. 99% of the cases were prescribed experimentally and 1% was based on culture. In 40.2% of the patients, drugs were prescribed irrationally in terms of prescription indications. In 84.3% of the cases, a change in treatment regimen was observed after receiving the culture results. Conclusion: A large percentage of cases of linezolid drug prescription was not done correctly. Furthermore, it has not been attention to the side effects caused by the drug, especially thrombocytopenia.
{"title":"Evaluation of Rational Use of Linezolid in Hospitalized Patient in Shahid Chamran Hospital in Isfahan City during the Second Six Months of the 2021","authors":"Fatemeh Bandegani, G. Afzal, Mehrnoush Dianatkhah, S. Sohrevardi","doi":"10.18502/ssu.v31i9.14186","DOIUrl":"https://doi.org/10.18502/ssu.v31i9.14186","url":null,"abstract":"Introduction: The rational use of drugs is one of the main elements of achieving the best pharmacotherapy method for patients. Linezolid is used for infections caused by gram-positive bacteria, including vancomycin-resistant staphylococci and vancomycin-resistant enterococci, but the inappropriate use of this drug has led to the emergence of linezolid-resistant strains. The purpose of this study was to investigate the manner of Linezolid prescription in Shahid Chamran Hospital of Isfahan City in 2021. Methods: This cross sectional study was conducted during a period of 6 months (From September 1, 2021 to February 31, 2022) on 102 patients admitted to Shahid Chamran Hospital in Isfahan City. Patient information such as demographic information, indication and dosages of drugs, the basis of drug prescription, side effects and drug interactions, etc. were extracted from the medical records of patients and hospital systems and recorded in designed forms. After matching the information with the relevant guidelines, statistical analysis was performed using SPSS-16 software. Results: Out of the 102 patients, who received linezolid, 75.1% were men and the rest were women. 99% of the cases were prescribed experimentally and 1% was based on culture. In 40.2% of the patients, drugs were prescribed irrationally in terms of prescription indications. In 84.3% of the cases, a change in treatment regimen was observed after receiving the culture results. Conclusion: A large percentage of cases of linezolid drug prescription was not done correctly. Furthermore, it has not been attention to the side effects caused by the drug, especially thrombocytopenia.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139232649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18502/ssu.v31i9.14188
Zahra Mohammadi, Masoumeh Asle Rousta, M. Rahnema
Introduction: In this study, we examined the impact of a hydroethanolic extract derived from ajwain and carvone (a compound present in ajwain), on learning, spatial memory, and anxiety levels in adult male rats that were chronically immobilized. Methods: There were 60 rats used in this study, divided into six groups of 10 rats each. To expose stress, 30 rats (in 3 groups including Stress, Stress-Carvone, and Stress-Ajwain groups) were placed in a restrainer for 6 hours every day for 21 consecutive days. Stress-Carvone and Stress-Ajwain groups received carvone (20 mg/kg) and ajwain extract (500 mg/kg) by gavage respectively. Thirty rats were also used in three groups (Control, Carvone, and Ajwain groups). Spatial learning and memory were studied using the Morris water maze, and anxiety was assessed by the elevated-plus maze. Results: Compared to the control group, chronic immobilization caused the rats to swim a longer time (P < 0.01) and distance (P < 0.05) to reach the hidden platform, and a shorter time and distance to swim in the target quarter (P < 0.05) in the Morris water maze. The percentage of entering the open arm in the elevated plus maze (P < 0.001) and the percentage of time staying in this arm (P < 0.01) were lower than the control group. The carvone improved the performance of stressed animals in the Morris maze, but the ajwain extract had no effect on the memory deficit of stressed animals. Furthermore, treating ajwain extract and carvone increased the percentage of entry into the open arm and the percentage of time spent in the open arm in animals exposed to stress. Conclusion: Ajwain extract and carvone reduce anxiety behavior in rats exposed to chronic immobility stress; carvone treatment prevents memory impairment in these animals. It is possible that the extract of ajwain (partially through carvone) is effective in reducing damage caused by stress in the nervous system.
{"title":"Effect of Ajwain Extract and Carvone on Behavioral Disorders Induced by Chronic Immobilization in Adult Male Rats","authors":"Zahra Mohammadi, Masoumeh Asle Rousta, M. Rahnema","doi":"10.18502/ssu.v31i9.14188","DOIUrl":"https://doi.org/10.18502/ssu.v31i9.14188","url":null,"abstract":"Introduction: In this study, we examined the impact of a hydroethanolic extract derived from ajwain and carvone (a compound present in ajwain), on learning, spatial memory, and anxiety levels in adult male rats that were chronically immobilized. Methods: There were 60 rats used in this study, divided into six groups of 10 rats each. To expose stress, 30 rats (in 3 groups including Stress, Stress-Carvone, and Stress-Ajwain groups) were placed in a restrainer for 6 hours every day for 21 consecutive days. Stress-Carvone and Stress-Ajwain groups received carvone (20 mg/kg) and ajwain extract (500 mg/kg) by gavage respectively. Thirty rats were also used in three groups (Control, Carvone, and Ajwain groups). Spatial learning and memory were studied using the Morris water maze, and anxiety was assessed by the elevated-plus maze. Results: Compared to the control group, chronic immobilization caused the rats to swim a longer time (P < 0.01) and distance (P < 0.05) to reach the hidden platform, and a shorter time and distance to swim in the target quarter (P < 0.05) in the Morris water maze. The percentage of entering the open arm in the elevated plus maze (P < 0.001) and the percentage of time staying in this arm (P < 0.01) were lower than the control group. The carvone improved the performance of stressed animals in the Morris maze, but the ajwain extract had no effect on the memory deficit of stressed animals. Furthermore, treating ajwain extract and carvone increased the percentage of entry into the open arm and the percentage of time spent in the open arm in animals exposed to stress. Conclusion: Ajwain extract and carvone reduce anxiety behavior in rats exposed to chronic immobility stress; carvone treatment prevents memory impairment in these animals. It is possible that the extract of ajwain (partially through carvone) is effective in reducing damage caused by stress in the nervous system.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139230971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Shift work disorder (SWD) is a sleep disorder that affects the circadian rhythm and is characterized by symptoms such as excessive daytime sleepiness and insomnia. This condition can significantly increase the risk of accidents and diminish the overall quality of life for individuals affected by it. Therefore, using the four-question of shift work disorder questionnaire (SWDQ) can be useful for identifying people at risk of SWD. In this research, we evaluated the accuracy and consistency of the Persian adaptation of the SWDQ among female employees.
Methods: In this descriptive cross-sectional investigation, a sampling available method was employed to select employed women who were referred to Royan Institute, Arash Hospital, and Gynecological Office in Tehran. It was used translated and reverse translation methods for the questionnaire of SWDQ. Statistical analysis was performed by using the Statistical Package for the Social Sciences (SPSS version 16, Inc. Chicago, IL, USA).The tests used in this study were Cronbach's alpha, internal correlation, and confirmatory factor analysis.
Results: In terms of content validity rate (CVR) with an average of 70% (questions 80%, 80%, 60% and 60%, respectively) and content validity index (CVI) with an average of 87.5% (questions 100%, 90%, 80% and 80%, respectively) was acceptable. The internal homogeneity of the SWD questionnaire with Cronbach's alpha was 63.4% and deleting each of the four items of the questionnaire reduced it. Moreover, the range of total correlated changes for the questionnaire was from 0.339 to 0.488, which was more than the minimum of 0.3.
Conclusion: Overall, the validity and reliability of the Persian version of SWDQ (the four-item) have acceptable.
{"title":"Psychometric of the Persian Version of Shift Work Disorder Questionnaire in Employee Women","authors":"Moini Ashraf, Farideh Malekzadeh, Behnaz Navid, Maryam Mohammadi, Reza Omani-Samani","doi":"10.18502/ssu.v31i8.13947","DOIUrl":"https://doi.org/10.18502/ssu.v31i8.13947","url":null,"abstract":"Introduction: Shift work disorder (SWD) is a sleep disorder that affects the circadian rhythm and is characterized by symptoms such as excessive daytime sleepiness and insomnia. This condition can significantly increase the risk of accidents and diminish the overall quality of life for individuals affected by it. Therefore, using the four-question of shift work disorder questionnaire (SWDQ) can be useful for identifying people at risk of SWD. In this research, we evaluated the accuracy and consistency of the Persian adaptation of the SWDQ among female employees.
 Methods: In this descriptive cross-sectional investigation, a sampling available method was employed to select employed women who were referred to Royan Institute, Arash Hospital, and Gynecological Office in Tehran. It was used translated and reverse translation methods for the questionnaire of SWDQ. Statistical analysis was performed by using the Statistical Package for the Social Sciences (SPSS version 16, Inc. Chicago, IL, USA).The tests used in this study were Cronbach's alpha, internal correlation, and confirmatory factor analysis.
 Results: In terms of content validity rate (CVR) with an average of 70% (questions 80%, 80%, 60% and 60%, respectively) and content validity index (CVI) with an average of 87.5% (questions 100%, 90%, 80% and 80%, respectively) was acceptable. The internal homogeneity of the SWD questionnaire with Cronbach's alpha was 63.4% and deleting each of the four items of the questionnaire reduced it. Moreover, the range of total correlated changes for the questionnaire was from 0.339 to 0.488, which was more than the minimum of 0.3.
 Conclusion: Overall, the validity and reliability of the Persian version of SWDQ (the four-item) have acceptable.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136158008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-29DOI: 10.18502/ssu.v31i8.13941
Mohsen Barghamdi, Leila Sabouri
Introduction: The purpose of this study was to review the research conducted on biomechanical and pathomechanical variables of the limbs of people with patellofemoral syndrome and also to summarize and present information in a useful framework from past researches.
Methods: The present study was systematic review. Keywords included: mechanics, pathomechanics of the lower limb, kinetics, kinematics, center of pressure and Electromyographic activity of lower limbs, patellofemoral syndrome on the sites of Google Scholar, Science Direct, Web of science, PubMed and Magiranwas searched One hundred nine articles were obtained by using the keywords of the study, and according to the intended purpose and removing duplicate articles, 48 articles were obtained, and according to the desired purpose, in the three parts of the patellofemoral joint, Plantar pressure variables and surrounding patellofemoral muscles were classified and analyzed in terms of mechanics, damage, forces on the joint, electrical activity of muscles and equipment used in the research in the form of tables and text.
Results: Displacement of the center of pressure in people with patellofemoral syndrome during using orthotics with corrective exercises was reduced. The main cause of pain in patellofemoral syndrome was the delay in the activity of vastus medialis and vastus lateralis muscles relative to each other, which caused the abnormal displacement of the patella to the side and as a result increased the pressure on the patellofemoral joint and eventually caused pain. Closed kinetic chain exercises and biofeedback strengthened the mentioned muscles.
Conclusion: Knowledge of the function of patellofemoral joint elements and orthoses and corrective exercises can help the mechanics and pathomechanics of people with patellofemoral syndrome.
前言:本研究的目的是回顾髌股综合征患者肢体的生物力学和病理力学变量的研究，并从过去的研究中总结和呈现信息。
方法:采用系统评价方法。关键词包括:在Google Scholar、Science Direct、Web of Science、PubMed和magiran4个网站上检索了本研究的关键词，获得了109篇论文，按照预定目的和去除重复文章，获得了48篇论文，按照预定目的，在髌股关节的三个部分，以表格和文字的形式对足底压力变量和髌股周围肌肉的力学、损伤、关节受力、肌肉电活动和研究中使用的设备进行分类和分析。
结果:髌骨综合征患者在使用矫形器和矫正运动时压力中心的移位减少。髌股综合征疼痛的主要原因是股内侧肌和股外侧肌相对活动延迟，导致髌骨向一侧异常移位，从而使髌股关节压力增大，最终引起疼痛。封闭动力链练习和生物反馈强化了上述肌肉。
结论:了解髌股关节元件的功能、矫形器和矫正运动对髌股综合征患者的力学和病理力学有帮助。
{"title":"Lower Extremity Mechanics and Pathomechanics of People with Patellofemoral Syndrome: A Review","authors":"Mohsen Barghamdi, Leila Sabouri","doi":"10.18502/ssu.v31i8.13941","DOIUrl":"https://doi.org/10.18502/ssu.v31i8.13941","url":null,"abstract":"Introduction: The purpose of this study was to review the research conducted on biomechanical and pathomechanical variables of the limbs of people with patellofemoral syndrome and also to summarize and present information in a useful framework from past researches.
 Methods: The present study was systematic review. Keywords included: mechanics, pathomechanics of the lower limb, kinetics, kinematics, center of pressure and Electromyographic activity of lower limbs, patellofemoral syndrome on the sites of Google Scholar, Science Direct, Web of science, PubMed and Magiranwas searched One hundred nine articles were obtained by using the keywords of the study, and according to the intended purpose and removing duplicate articles, 48 articles were obtained, and according to the desired purpose, in the three parts of the patellofemoral joint, Plantar pressure variables and surrounding patellofemoral muscles were classified and analyzed in terms of mechanics, damage, forces on the joint, electrical activity of muscles and equipment used in the research in the form of tables and text.
 Results: Displacement of the center of pressure in people with patellofemoral syndrome during using orthotics with corrective exercises was reduced. The main cause of pain in patellofemoral syndrome was the delay in the activity of vastus medialis and vastus lateralis muscles relative to each other, which caused the abnormal displacement of the patella to the side and as a result increased the pressure on the patellofemoral joint and eventually caused pain. Closed kinetic chain exercises and biofeedback strengthened the mentioned muscles.
 Conclusion: Knowledge of the function of patellofemoral joint elements and orthoses and corrective exercises can help the mechanics and pathomechanics of people with patellofemoral syndrome.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136157364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Helicobacter pylori infection is known as one of the health problems in the world, and the concurrent infection of diabetics with Helicobacter pylori contributes to health and economic problems in the world. The present study was conducted to investigate the prevalence of Helicobacter pylori in patients with type 2 diabetes in Gonabad City, Iran.
Methods: This case-control study was conducted in Gonabad City, Iran. The number of participants in the study was 168. The method was simple random sampling and the study population was typing 2 diabetic and non-diabetic people who were referred to Gonabad health centers. After obtaining informed consent from the patients, 4 milliliters of venous blood were collected from the patients with type 2 diabetes and the control group, and IgG antibodies against Helicobacter pylori and Fasting Blood Sugar and Glycosylated Hemoglobin (HbA1C) were measured by ELISA and Colorimetric method, respectively. After entering the data into SPSS version 16 software, they were analyzed using independent tests, chi-square tests, and logistic regression tests.
Results: In the present study, 71.4% of type 2 diabetes patients had IgG antibodies against H. pylori bacteria. The odds ratio of diabetes in the patients with positive IgG was 1.37 times that of patients with negative IgG, and this relationship was statistically significant (P=0.003).
Conclusion: The present study showed that H. pylori was more common in diabetic patients than non-diabetic ones, and in diabetic patients, there was no statistically significant relationship between the duration of diabetes, family history of diabetes, and smoking history with Helicobacter pylori infection.
{"title":"Investigating the Relationship between Type 2 Diabetes and Helicobacter Pylori","authors":"Alireza Mohammadzadeh, Seyed Hossein Abtahi Eivary, Nasim Khajavian, Jafar Hajavi","doi":"10.18502/ssu.v31i8.13946","DOIUrl":"https://doi.org/10.18502/ssu.v31i8.13946","url":null,"abstract":"Introduction: Helicobacter pylori infection is known as one of the health problems in the world, and the concurrent infection of diabetics with Helicobacter pylori contributes to health and economic problems in the world. The present study was conducted to investigate the prevalence of Helicobacter pylori in patients with type 2 diabetes in Gonabad City, Iran.
 Methods: This case-control study was conducted in Gonabad City, Iran. The number of participants in the study was 168. The method was simple random sampling and the study population was typing 2 diabetic and non-diabetic people who were referred to Gonabad health centers. After obtaining informed consent from the patients, 4 milliliters of venous blood were collected from the patients with type 2 diabetes and the control group, and IgG antibodies against Helicobacter pylori and Fasting Blood Sugar and Glycosylated Hemoglobin (HbA1C) were measured by ELISA and Colorimetric method, respectively. After entering the data into SPSS version 16 software, they were analyzed using independent tests, chi-square tests, and logistic regression tests.
 Results: In the present study, 71.4% of type 2 diabetes patients had IgG antibodies against H. pylori bacteria. The odds ratio of diabetes in the patients with positive IgG was 1.37 times that of patients with negative IgG, and this relationship was statistically significant (P=0.003).
 Conclusion: The present study showed that H. pylori was more common in diabetic patients than non-diabetic ones, and in diabetic patients, there was no statistically significant relationship between the duration of diabetes, family history of diabetes, and smoking history with Helicobacter pylori infection.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136157865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-29DOI: 10.18502/ssu.v31i8.13943
Mohammad Dehghani Mahmoudabadi, Iravan Masoudi Asl, Soad Mahfoozpour, Somayeh Hessam
Introduction: Health tourism is an organized trip from one's living environment to another place, which is done in order to maintain, improve and regain physical and mental health. The purpose of this research was to identify the most important factors affecting medical tourism in Iran.
Methods: This was a fundamental study that was conducted in two phases. The first phase consisted of two steps. The first step was to perform a systematic review with the keyword of "MEDICAL TOURISM" on Web of Science and select 434 articles, and the second step was to perform a scientometric analysis on these articles using VOSviewer software. The second phase consisted of three steps. The first step was a systematic review with some keywords, including "MEDICAL TOURISM" and "medical tourism" on foreign and domestic databases and selecting 63 articles. The second step was to perform a content analysis on the selected articles using Nvivo software and identify the components affecting medical tourism in the world. The third step was the implementation of a Delphi method using a Likert scale with the aim of identifying the most important factors affecting medical tourism in Iran from the point of view of academic experts.
Results: The first phase showed that the scope of research on the topic of medical tourism in the world had an upward trend from 1975 to 2020, and the countries of America, Canada, Malaysia, South Korea and Iran were the top 5 countries in this field. In the second phase, 46 factors affecting medical tourism in the world were identified, and after summarizing the opinions of experts, 39 indicators were determined as indicators affecting medical tourism in Iran.
Conclusion: Considering the high number and variety of factors affecting medical tourism in Iran, the development of this industry in the country requires extensive intra- and inter-sectorial coordination.
健康旅游是一种有组织的旅行，从一个人的生活环境到另一个地方，这样做是为了保持、改善和恢复身心健康。本研究的目的是确定影响伊朗医疗旅游的最重要因素。
方法:本研究为基础研究，分两期进行。第一阶段包括两个步骤。第一步在Web of Science上以“MEDICAL TOURISM”为关键词进行系统综述，选取434篇文章，第二步使用VOSviewer软件对这些文章进行科学计量分析。第二阶段包括三个步骤。第一步以“医疗旅游”、“医疗旅游”等关键词对国内外数据库进行系统综述，选取63篇文章。第二步是使用Nvivo软件对选定的文章进行内容分析，并确定影响世界医疗旅游的组成部分。第三步是使用李克特量表实施德尔菲法，目的是从学术专家的角度确定影响伊朗医疗旅游的最重要因素。结果:第一阶段研究表明，从1975年到2020年，世界各国对医疗旅游主题的研究范围呈上升趋势，其中美国、加拿大、马来西亚、韩国和伊朗是该领域前5位的国家。在第二阶段，确定了全球46个影响医疗旅游的因素，在总结专家意见后，确定了39个指标作为影响伊朗医疗旅游的指标。
结论:考虑到影响伊朗医疗旅游的因素数量众多，种类繁多，该国该行业的发展需要广泛的部门内和部门间协调。
{"title":"Identifying the Research Extent of Medical Tourism in the World and the Components of Attracting Medical Tourists in Iran","authors":"Mohammad Dehghani Mahmoudabadi, Iravan Masoudi Asl, Soad Mahfoozpour, Somayeh Hessam","doi":"10.18502/ssu.v31i8.13943","DOIUrl":"https://doi.org/10.18502/ssu.v31i8.13943","url":null,"abstract":"Introduction: Health tourism is an organized trip from one's living environment to another place, which is done in order to maintain, improve and regain physical and mental health. The purpose of this research was to identify the most important factors affecting medical tourism in Iran.
 Methods: This was a fundamental study that was conducted in two phases. The first phase consisted of two steps. The first step was to perform a systematic review with the keyword of \"MEDICAL TOURISM\" on Web of Science and select 434 articles, and the second step was to perform a scientometric analysis on these articles using VOSviewer software. The second phase consisted of three steps. The first step was a systematic review with some keywords, including \"MEDICAL TOURISM\" and \"medical tourism\" on foreign and domestic databases and selecting 63 articles. The second step was to perform a content analysis on the selected articles using Nvivo software and identify the components affecting medical tourism in the world. The third step was the implementation of a Delphi method using a Likert scale with the aim of identifying the most important factors affecting medical tourism in Iran from the point of view of academic experts.
 Results: The first phase showed that the scope of research on the topic of medical tourism in the world had an upward trend from 1975 to 2020, and the countries of America, Canada, Malaysia, South Korea and Iran were the top 5 countries in this field. In the second phase, 46 factors affecting medical tourism in the world were identified, and after summarizing the opinions of experts, 39 indicators were determined as indicators affecting medical tourism in Iran.
 Conclusion: Considering the high number and variety of factors affecting medical tourism in Iran, the development of this industry in the country requires extensive intra- and inter-sectorial coordination.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136158013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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