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Evaluating natural planned exposure protocols on rotavirus shedding patterns in gilts and the impact on their suckling pigs 评估自然计划暴露方案对母猪轮状病毒脱落模式及其对乳猪的影响
IF 0.7 4区 农林科学 Q3 Agricultural and Biological Sciences Pub Date : 2023-01-01 DOI: 10.54846/jshap/1294
Amanda Anderson, Frances K. Shepherd, Francisco Dominguez, J. Pittman, D. Marthaler, L. Karriker
Objective: The objectives of this study were to determine the pattern of rotavirus A (RVA), rotavirus B (RVB), and rotavirus C (RVC) shedding in gilts after natural planned exposure (NPE) administration and assess the effects on piglet weaning weight, preweaning mortality, and RV shedding. Materials and methods: A total of 70 pregnant gilts were enrolled and allocated into 4 groups. Group 1 was given NPE at 5, 4, and 3 weeks prefarrowing (WPF); Group 2 at 5 and 3 WPF; and Group 3 at 5 WPF only. Group 4 (control group) did not receive any NPE. Samples from 46 gilts and litters (5 piglets/litter) were tested at 12 sample times. Piglets were sampled weekly from 24 hours of age until 6 weeks of age and tested by quantitative reverse transcriptase-polymerase chain reaction for RVA, RVB, and RVC. Results: There was a significant improvement in weaning weight of piglets born to gilts that received 3 NPE administrations compared to fewer or no NPE administrations. Shedding of RVA and RVB from piglets were well controlled in the farrowing room regardless of treatment group, but RVC was observed as early as 1 week old. This study was conducted on a single farm, and the results should be carefully interpreted with knowledge of variations in farms and systems. Implications: Three administrations of NPE to gilts prefarrowing had valuable production and economic benefits for the producer. Circulation patterns of RVA, RVB, and RVC appear to correlate; interventions for one have value against the others.
目的:本研究的目的是确定自然计划暴露(NPE)给药后母猪轮状病毒A(RVA)、轮状病毒B(RVB)和轮状病毒C(RVC)脱落的模式,并评估其对仔猪断奶体重、断奶前死亡率和RV脱落的影响。材料和方法:将70头妊娠母猪随机分为4组。第1组在出生前5、4和3周给予NPE(WPF);第2组为5和3 WPF;而第3组仅为5WPF。第4组(对照组)未接受任何NPE。对46头母猪和窝仔(5头仔猪/窝)的样本进行了12次取样测试。从24小时龄到6周龄,每周对仔猪进行取样,并通过定量逆转录聚合酶链式反应检测RVA、RVB和RVC。结果:与较少或不施用NPE相比,施用3次NPE的母猪所产仔猪的断奶体重显著提高。无论治疗组如何,在产仔室都能很好地控制仔猪RVA和RVB的脱落,但早在1周大时就观察到RVC。这项研究是在一个农场上进行的,应该根据农场和系统的变化来仔细解释结果。影响:NPE对金边债券预售的三次管理为生产商带来了宝贵的生产和经济效益。RVA、RVB和RVC的循环模式似乎是相关的;一方的干预措施对另一方有价值。
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引用次数: 0
Supplementary Material: Water use patterns within each day: Variation between batches of growing pigs in commercial production systems 补充材料:每天的用水模式:商业生产系统中不同批次生长猪的变化
IF 0.7 4区 农林科学 Q3 Agricultural and Biological Sciences Pub Date : 2023-01-01 DOI: 10.54846/jshap/1297suppl1
S. Little, A. Woodward, G. Browning, H. Billman-Jacobe
Objective: To measure, describe, and compare the water use patterns within each day for multiple cohorts of weaner, grower, and finisher pigs in farm buildings. Materials and methods: Prospective, observational cohort studies of the water use patterns within each day were conducted in 5 pig buildings using either a turbine or ultrasonic water flow meter attached to the main water pipe entering each building. Water use data were collected from multiple batches of pigs (second-stage weaners over eleven 48-day periods and grower-finishers over 4 periods of 21-43 days). Semi-parametric models of pig water use patterns within each day were estimated using the brms software package in R. To estimate the interacting effects of time and pig body weight on water use by pigs, we used tensor product smooths for time and pig body weight. Results: The water use pattern within each day varied between the cohorts, and the pattern of many cohorts changed as the pigs gained weight. Some patterns were unimodal and others were bimodal, with the main peak in water use occurring early afternoon to late afternoon. Implications: Water use patterns of pigs within each day varied between and within cohorts. The water use pattern of one cohort cannot be used reliably to predict that of other cohorts, even if they are reared in the same building. Water use pattern data may be valuable for optimizing in-water antimicrobial dosing regimens.
目的:测量、描述和比较农场建筑物中多组断奶猪、生长猪和育肥猪每天的用水模式。材料和方法:在5个猪舍中进行了每天用水模式的前瞻性观察队列研究,使用涡轮机或超声波水表连接在每个建筑物的主水管上。收集了多批次猪的用水数据(11个48天的第二断奶期和4个21-43天的生长育肥猪)。为了估计时间和猪体重对猪用水的交互影响,我们使用了时间和猪体重的张量积平滑来估计猪每天用水模式的半参数模型。结果:各组之间每天的用水模式不同,许多组的模式随着猪体重的增加而改变。一些模式为单峰模式,另一些模式为双峰模式,用水高峰出现在下午早些时候到下午晚些时候。含义:猪每天的用水模式在同一群之间和同一群之间是不同的。一个群体的用水模式不能可靠地用来预测其他群体的用水模式,即使他们是在同一栋楼里长大的。用水模式数据可能对优化水中抗菌素给药方案有价值。
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引用次数: 0
Maximizing value and minimizing waste in clinical trial research in swine: Selecting interventions to build an evidence base 猪临床试验研究中的价值最大化和浪费最小化:选择干预措施以建立证据基础
IF 0.7 4区 农林科学 Q3 Agricultural and Biological Sciences Pub Date : 2022-11-01 DOI: 10.54846/jshap/1295
J. Sargeant, A. O'Connor, T. O’Sullivan, A. Ramirez
Researchers conduct a trial to compare an intervention of interest to a comparison group. Initially, researchers should determine whether a trial is evaluating superiority, equivalence, or noninferiority. This decision will guide the choice of a placebo versus active comparison group. Interventions, as well as baseline management, should be comprehensively reported to allow replication or clinical application. It is necessary to build a body of evidence across multiple trials to apply evidence-based decision-making. To achieve this, at least one intervention in every trial should be an intervention that has been used in at least one previously published trial.
研究人员进行了一项试验,将感兴趣的干预措施与对照组进行比较。最初,研究人员应该确定试验是否评估优越性、等效性或非劣效性。这一决定将指导安慰剂组和积极对照组的选择。干预措施以及基线管理应全面报告,以便复制或临床应用。有必要建立一个跨多个试验的证据体,以应用基于证据的决策。为达到这一目的,每项试验中至少有一项干预措施应该是在至少一项先前发表的试验中使用过的干预措施。
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引用次数: 1
Evaluation of biosecurity measures on a swine operation using Glo Germ powder as a visible learning aid 使用Glo Germ粉末作为可视学习辅助工具评估猪手术的生物安全措施
IF 0.7 4区 农林科学 Q3 Agricultural and Biological Sciences Pub Date : 2022-11-01 DOI: 10.54846/jshap/1289
O. Harrison, P. Dahmer, J. Gebhardt, C. Paulk, J. Woodworth, Cassandra K. Jones
Glo Germ powder was used to determine the efficacy of common biosecurity practices to prevent the powder from spreading to other areas within a farm. Pictures from 4 locations were taken before and after personnel movement to observe any differences in Glo Germ coverage. The percentage of Glo Germ coverage observed in the pictures was evaluated by 47 panelists and averaged. The area without biosecurity measures had more Glo Germ coverage than the 3 areas with biosecurity measures (P < .001). The use of Glo Germ can be used as a learning aid to demonstrate the efficacy of common biosecurity practices.
Glo Germ粉末用于确定防止该粉末扩散到农场内其他区域的常见生物安全措施的有效性。从4个地点拍摄了人员移动前后的照片,以观察全球细菌覆盖率的差异。47名小组成员评估了图片中观察到的全球细菌覆盖率百分比并取平均值。未采取生物安全措施地区的Glo Germ盖度高于采取生物安全措施地区(P < 0.001)。Glo Germ的使用可以作为一种学习辅助工具,以证明常见生物安全做法的有效性。
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引用次数: 0
HMH sked rescue system, revised deer sled, and ice fishing sled as humane on-farm handling tools to move nonambulatory grow-finish pigs on a commercial farm HMH滑雪救援系统,改进的鹿雪橇和冰钓雪橇作为人性化的农场搬运工具,在商业农场移动非活动的生长肥育猪
IF 0.7 4区 农林科学 Q3 Agricultural and Biological Sciences Pub Date : 2022-11-01 DOI: 10.54846/jshap/1301
Ella Akin, Anna Johnson, Cassandra Jass, Locke Karrkier, Jason Ross, K. Stalder, S. Millman
Objective: The objective of this study was to evaluate an HMH sked rescue system, revised deer sled, and ice fishing sled as humane handling tools for moving nonambulatory pigs on a commercial wean-to-finish farm. Materials and methods: Eighteen commercial crossbred pigs received an epidural to induce a nonambulatory state. The HMH sked rescue system, revised deer sled, and ice fishing sled were tested as handling tools by 2 employees for time to place and move the pig, pig vocalization and struggle scores, and tool durability. Results: Time to place the nonambulatory pig from the start pen floor onto the handling tool, time to secure the nonambulatory pig on the handling tool, and total time were not affected by the handling tool (P ≥ .12). There was a trend for time to move the handling tool with the nonambulatory pig from the start to end pen, which included removing the pig from the handling tool and placing them onto the end pen floor (P = .06). The ice fishing sled was the most durable with no creases, rips, or holes. There were no handling tool differences for pig vocalization or struggle scores (P > .10). Changes in pig respiration rate and pig body temperature did not differ between handling tools (P ≥ .71). Implications: Under study conditions, the sked, revised deer sled, and ice fishing sled were all humane tools to move nonambulatory grow-finish pigs. Caretakers need to evaluate the best choice for their farm.
目的:本研究的目的是评估HMH雪橇救援系统、改良的鹿雪橇和冰钓雪橇作为人道的处理工具,用于将商业断奶仔猪运至牧场。材料和方法:18头商品杂交猪接受硬膜外麻醉以诱导非卧床状态。HMH雪橇救援系统、改良的鹿雪橇和冰上捕鱼雪橇由2名员工作为搬运工具进行了测试,测试内容包括放置和移动猪的时间、猪的发声和挣扎得分以及工具的耐用性。结果:将不动产清管器从起始围栏地面放置到处理工具上的时间、将不动资产清管器固定在处理工具上时间和总时间不受处理工具的影响(P≥.12),其中包括将清管器从装卸工具上取下,并将其放置在围栏末端的地板上(P=.06)。冰钓雪橇是最耐用的,没有褶皱、撕裂或孔洞。在猪发声或挣扎得分方面,处理工具没有差异(P>0.05)。不同处理工具之间猪呼吸速率和猪体温的变化没有差异(P≥.71)。提示:在研究条件下,雪橇、改良鹿雪橇和冰钓雪橇都是移动不动产生长肥猪的人道工具。看护人需要评估他们农场的最佳选择。
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引用次数: 0
Maximizing value and minimizing waste in swine research: Availability and accessibility of research reports 猪研究中的价值最大化和浪费最小化:研究报告的可用性和可及性
IF 0.7 4区 农林科学 Q3 Agricultural and Biological Sciences Pub Date : 2022-09-01 DOI: 10.54846/jshap/1291
J. Sargeant, A. O'Connor, T. O’Sullivan, A. Ramirez, A. Versluis
To be useful for decision-making, research results need to be available. This means that full reports (methods and results) for trials need to be published, preferably in a journal. However, there is evidence that only a small proportion of swine trials presented at conferences are subsequently published in journals. This is problematic, as results may differ between a conference presentation and journal publication. Published results also need to be accessible, either through open-access or traditional journals or through other sources that do not violate copyright agreements. Researchers should strive to make full research reports widely available.
为了对决策有用,研究结果需要可用。这意味着试验的完整报告(方法和结果)需要发表,最好是在期刊上发表。然而,有证据表明,只有一小部分在会议上提出的猪试验随后在期刊上发表。这是有问题的,因为会议报告和期刊出版物的结果可能不同。发表的结果也需要是可访问的,无论是通过开放获取或传统期刊,还是通过不违反版权协议的其他来源。研究人员应努力使完整的研究报告广泛可用。
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引用次数: 1
Rapid application of long-acting ceftiofur can prevent death losses associated with Streptococcus equi subspecies zooepidemicus in pigs 快速应用长效头孢噻呋可预防猪中马链球菌亚种动物流行病相关的死亡损失
IF 0.7 4区 农林科学 Q3 Agricultural and Biological Sciences Pub Date : 2022-09-01 DOI: 10.54846/jshap/1298
Samantha J. Hau, A. Buckley, S. Brockmeier
Objective: Introduction of Streptococcus equi subspecies zooepidemicus strains into naive populations results in field mortality rates of 30% to 50% over 5 to 10 days. Because of the rapid disease progression, our goal was to determine whether antibiotic intervention could control S zooepidemicus disease in a group of animals following development of clinical signs. Materials and methods: Thirty-two pigs were challenged with S equi subsp zooepidemicus. Following the development of clinical signs, 16 were treated with long-acting, injectable ceftiofur. Seven unchallenged pigs served as controls. Clinical signs were monitored following challenge and survival was compared between groups. Antibody titers were measured on day 0 and day 30 post challenge. On day 30 post challenge, 3 contact pigs were commingled with 2 treated animals to evaluate S equi subsp zooepidemicus transmission. Results: Ceftiofur treatment eliminated clinical signs in 15 of 16 animals. However, multiple treatments were required to control disease in treated animals (2-3 doses providing 12-18 days of coverage). Antibody titers to S equi subsp zooepidemicus increased in challenged animals treated with ceftiofur, indicating sufficient exposure for immune stimulation. No contact pigs developed clinical signs of S equi subsp zooepidemicus following exposure. Implication: Rapid application of injectable antibiotics is a viable method to reduce losses due to the introduction of S equi subsp zooepidemicus into a naive group of pigs and may help prevent transmission to contact animals following recovery.
目的:将马链球菌亚种动物流行病菌株引入原始种群,在5至10天内可导致30%至50%的田间死亡率。由于疾病进展迅速,我们的目标是确定抗生素干预是否可以在临床症状发展后控制一组动物的S型动物流行病。材料与方法:用马疫亚种攻击32头猪。随着临床症状的发展,16人接受了长效注射用头孢噻呋的治疗。七头未受挑战的猪作为对照。激发后监测临床症状,并比较各组的生存率。在激发后第0天和第30天测量抗体滴度。在攻击后第30天,将3头接触猪与2只处理过的动物混合,以评估马疫亚种的传播。结果:头孢噻呋治疗消除了16只动物中15只的临床症状。然而,需要多种治疗来控制治疗动物的疾病(2-3剂,覆盖12-18天)。在接受头孢噻呋治疗的受攻击动物中,对马兽疫亚种的抗体滴度增加,表明有足够的免疫刺激暴露。没有接触过的猪在接触后出现马疫亚种的临床症状。含义:快速应用注射抗生素是一种可行的方法,可以减少由于将马疫亚种引入一组幼稚的猪中而造成的损失,并可能有助于防止康复后传播给接触动物。
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引用次数: 0
Acute Mycoplasma hyopneumoniae infection in a naive breed-to-wean herd 急性肺炎支原体感染在未出生的种猪到断奶的牛群
IF 0.7 4区 农林科学 Q3 Agricultural and Biological Sciences Pub Date : 2022-09-01 DOI: 10.54846/jshap/1279
T. Gillespie, Oliver Gomez Duran
Mycoplasma hyopneumoniae (MHP) infection occurs globally and contributes to economic losses. Acute infections occur in immunologically naive populations affecting pigs of all ages and causing clinical signs including fever, coughing, acute respiratory distress, and death. An acute MHP infection was investigated in a naive 4200-sow breed-to-wean herd. An increase in sow mortality (4.16%, 8.33%, and 3.89%) and preweaning mortality (10.45%, 12.38%, and 12.06%) occurred when comparing the naive, acute infection, and post-infection periods, respectively. Further production differences included 166.3, 158.3, and 164.2 kg weaned/sow/year and 29.43, 28.35, and 28.28 pigs weaned/mated female/year in naive, acute infection, and post-infection periods, respectively.
肺炎支原体(MHP)感染在全球范围内发生,并造成经济损失。急性感染发生在未免疫的猪群中,影响所有年龄的猪,并引起临床症状,包括发烧、咳嗽、急性呼吸窘迫和死亡。在一个4200头从种到断奶的母猪群中调查了急性MHP感染。与初感染期、急性感染期和感染后期相比,母猪死亡率分别增加了4.16%、8.33%和3.89%,断奶前死亡率分别增加了10.45%、12.38%和12.06%。在初感染期、急性感染期和感染后,每头母猪断奶体重分别为166.3、158.3和164.2公斤/年,每头交配母猪断奶体重分别为29.43、28.35和28.28公斤/年。
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引用次数: 0
A survey of vitamin and trace mineral ranges for diagnostic lab reporting from conventionally raised swine 用于常规饲养猪诊断实验室报告的维生素和微量矿物质范围调查
IF 0.7 4区 农林科学 Q3 Agricultural and Biological Sciences Pub Date : 2022-09-01 DOI: 10.54846/jshap/1286
L. Greiner, S. Elefson, S. Radke, C. Hagen, D. Humphrey, S. Becker
Objective: The purpose of this study was to survey the vitamin and mineral levels in various pig tissues at different phases of the life cycle. Materials and methods: Forty-eight healthy pigs of different stages of production were used for sampling of different tissues. Seven sows and a minimum of 10 animals from each phase of production (suckling, nursery, and finishing) were selected for sampling. A blood sample was collected via sterile venipuncture for serum vitamin and mineral analysis. After euthanasia, the diaphragm and liver were collected. Samples were submitted to the Iowa State University Veterinary Diagnostic Laboratory for analysis. Data were analyzed using SAS (version 9.4; SAS Institute Inc) and presented as minimum and maximum concentrations with standard error. The experimental unit was the animal. Results: Levels of vitamin A, vitamin E, copper, zinc, selenium, iron, and manganese were higher in liver tissues than in serum and diaphragm tissues. Diaphragm muscle had similar levels of phosphorus as the liver tissue. Serum had similar levels of calcium as the liver tissue. Implications: These data provide a sampling of vitamin and mineral levels present in tissues and serum of commercial pigs and suggests that vitamin and mineral levels differ between sampling sites.
目的:研究猪生命周期不同阶段各组织中维生素和矿物质的含量。材料与方法:选用不同生产阶段的健康猪48头,进行不同组织取样。从每个生产阶段(哺乳、保育和育肥)选择7头母猪和至少10头动物进行抽样。通过无菌静脉穿刺采集血样进行血清维生素和矿物质分析。安乐死后,取横膈膜和肝脏。样本被送到爱荷华州立大学兽医诊断实验室进行分析。使用SAS (version 9.4;SAS Institute Inc),并以标准误差的最小和最大浓度表示。实验单位是动物。结果:肝组织中维生素A、维生素E、铜、锌、硒、铁和锰的含量高于血清和膈肌组织。横膈膜肌的磷含量和肝组织相似。血清中钙的含量与肝组织相似。意义:这些数据提供了商品猪组织和血清中维生素和矿物质水平的采样,并表明不同采样地点的维生素和矿物质水平不同。
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引用次数: 3
Environmental monitoring of porcine epidemic diarrhea virus within a swine farm during a disease outbreak 疾病暴发期间养猪场内猪流行性腹泻病毒的环境监测
IF 0.7 4区 农林科学 Q3 Agricultural and Biological Sciences Pub Date : 2022-09-01 DOI: 10.54846/jshap/1273
Savannah C. Stewart, Cassandra Jones, J. Gebhardt, J. Woodworth, C. Paulk, C. Vier, O. Harrison, Charles Zumbaugh, S. Dritz
Environmental swabs were used as a monitoring tool during a porcine epidemic diarrhea virus outbreak at a farrow-to-finish swine facility. Samples were collected over the course of 16 weeks following initial infection, and changes in biosecurity practices were implemented based on results. Separation of on-farm areas into different zones as determined by animal and feed ingredient contact and proximity allowed for a targeted approach to clean-up efforts.
在猪流行性腹泻病毒爆发期间,环境拭子被用作监测工具。在初次感染后的16周内收集了样本,并根据结果实施了生物安全措施的改变。根据动物和饲料成分的接触和接近程度,将农场区域划分为不同的区域,以便有针对性地开展清理工作。
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引用次数: 0
期刊
Journal of Swine Health and Production
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