Pub Date : 2024-05-05DOI: 10.52228/jrub.2024-37-1-5
Lavkesh Kumar Singh Tanwar, Kallol K Ghosh
Imidazolium-based ionic liquids have emerged as promising bio-compatible solvents for bio-molecules. The interaction of two imidazolium-based ionic liquids, namely 1-decyl-3-methyl-imidazolium tetrafluoroborate [Dmim][BF4] and 1-butyl-3-methylimidazolium octylsulfate [Bmim][OS], with human serum albumin (HSA) have been investigated using UV-visible, fluorescence and fourier transform infrared spectroscopy. Stern-Volmer quenching constant (Ksv) and the binding affinity (Ka) value have been also calculated to reveals the molecular interactions between HSA and the imidazolium-based ILs. Additionally, we explored the thermodynamic feasibility of these interactions by calculating the Gibbs free energy (∆G), entropy (∆S), and enthalpy (∆H). Hydrophobic interactions have been identified as exerting a more significant influence than hydrogen bonding in the interactions between proteins and ionic liquids. This implies that the hydrophobic characteristics of the ionic liquids play a pivotal role in the denaturation of proteins. Consequently, we conclude that the hydrophobic nature of the ionic liquids is essential for inducing interactions with proteins and potentially contributing to protein structure denaturation.
咪唑基离子液体已成为一种很有前途的生物大分子生物兼容溶剂。本研究利用紫外-可见光、荧光和傅立叶变换红外光谱研究了两种咪唑基离子液体，即 1-癸基-3-甲基咪唑鎓四氟硼酸盐[Dmim][BF4]和 1-丁基-3-甲基咪唑鎓辛基硫酸盐[Bmim][OS]与人血清白蛋白（HSA）的相互作用。还计算了斯特恩-沃尔默淬灭常数（Ksv）和结合亲和力（Ka）值，以揭示 HSA 与咪唑基 IL 之间的分子相互作用。此外，我们还通过计算吉布斯自由能（ΔG）、熵（ΔS）和焓（ΔH）来探索这些相互作用的热力学可行性。在蛋白质与离子液体的相互作用中，疏水相互作用被认为比氢键作用具有更重要的影响。这意味着离子液体的疏水特性在蛋白质变性过程中起着关键作用。因此，我们得出结论：离子液体的疏水性对于诱导与蛋白质的相互作用以及可能导致蛋白质结构变性至关重要。
{"title":"Studies on the Interaction of Imidazolium Ionic Liquids with Human Serum Albumin","authors":"Lavkesh Kumar Singh Tanwar, Kallol K Ghosh","doi":"10.52228/jrub.2024-37-1-5","DOIUrl":"https://doi.org/10.52228/jrub.2024-37-1-5","url":null,"abstract":"\u0000 Imidazolium-based ionic liquids have emerged as promising bio-compatible solvents for bio-molecules. The interaction of two imidazolium-based ionic liquids, namely 1-decyl-3-methyl-imidazolium tetrafluoroborate [Dmim][BF4] and 1-butyl-3-methylimidazolium octylsulfate [Bmim][OS], with human serum albumin (HSA) have been investigated using UV-visible, fluorescence and fourier transform infrared spectroscopy. Stern-Volmer quenching constant (Ksv) and the binding affinity (Ka) value have been also calculated to reveals the molecular interactions between HSA and the imidazolium-based ILs. Additionally, we explored the thermodynamic feasibility of these interactions by calculating the Gibbs free energy (∆G), entropy (∆S), and enthalpy (∆H). Hydrophobic interactions have been identified as exerting a more significant influence than hydrogen bonding in the interactions between proteins and ionic liquids. This implies that the hydrophobic characteristics of the ionic liquids play a pivotal role in the denaturation of proteins. Consequently, we conclude that the hydrophobic nature of the ionic liquids is essential for inducing interactions with proteins and potentially contributing to protein structure denaturation. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.52228/jrub.2024-37-1-4
Sonam Patel, Afreen Anjum, Veenu Joshi, A. Quraishi
Curcuma caesia Roxb. is a highly valuable, endangered herb of therapeutic importance that resides in their rhizomes. In the present investigation, the effect of ½ strength liquid Murashige and Skoog (MS) medium supplemented with 1 mg/l Indole-3-butyric acid (IBA) and different sucrose concentrations (1.5%, 3%, 6%, 9%, or 12%) was studied on microrhizomes induction of C. caesia. The shoot length, root length and microrhizomes dry weight of C. caesia decreased significantly at 6% sucrose and above. When compared to the control (1.5% sucrose), the current water content significantly decreased at 6% sucrose. The optimum concentration for in vitro microrhizomes induction in C. caesia was 6% sucrose. Therefore for further experiments, the 6% sucrose was used. We also studied the effect of silver nanoparticles (AgNP) on microrhizome induction and antioxidant activity in C. caesia cultures. Field-grown C. caesia rhizomes extract was used in the green synthesis of AgNP. The synthesized AgNP was further characterized through scanning electron microscopy and X-ray diffraction. The AgNP, ranging from 0, 0.025, 0.05, 0.075 or 0.1 mg/l was supplemented in ½ strength liquid MS medium with 6% sucrose and 1 mg/l IBA. The MS medium with 0.05 mg/l AgNP found with significant morphological changes in C. caesia cultures (root number, root length and microrhizomes fresh weight). For the total phenolic and total terpenoids content estimation as well as for antioxidant activity analysis, the extracts of un-treated cultures (6% sucrose + 1 mg/l IBA, without AgNP), AgNP treated cultures (6% sucrose + 1 mg/l IBA with 0.025 and 0.05 mg/l AgNP) was used. The 0.025 and 0.05 mg/l AgNP enhanced the phenolic and terpenoid content in the cultures compared to the field-grown mother plant. The antioxidant activity of the cultures treated with AgNP also increased compared to un-treated cultures and field-grown mother plant. The Gas Chromatography-Mass Spectrometry (GC-MS) analysis revealed that the extract treated with 0.05 mg/l AgNP had increased production of monoterpene (camphor) and sesquiterpenes (β-elemenone and curcumenone). These increased terpenes could be responsible for the enhanced antioxidant activity of C. caesia cultures.
{"title":"Enhanced antioxidant activity in Curcuma caesia Roxb. microrhizomes treated with silver nanoparticles","authors":"Sonam Patel, Afreen Anjum, Veenu Joshi, A. Quraishi","doi":"10.52228/jrub.2024-37-1-4","DOIUrl":"https://doi.org/10.52228/jrub.2024-37-1-4","url":null,"abstract":"\u0000 Curcuma caesia Roxb. is a highly valuable, endangered herb of therapeutic importance that resides in their rhizomes. In the present investigation, the effect of ½ strength liquid Murashige and Skoog (MS) medium supplemented with 1 mg/l Indole-3-butyric acid (IBA) and different sucrose concentrations (1.5%, 3%, 6%, 9%, or 12%) was studied on microrhizomes induction of C. caesia. The shoot length, root length and microrhizomes dry weight of C. caesia decreased significantly at 6% sucrose and above. When compared to the control (1.5% sucrose), the current water content significantly decreased at 6% sucrose. The optimum concentration for in vitro microrhizomes induction in C. caesia was 6% sucrose. Therefore for further experiments, the 6% sucrose was used. We also studied the effect of silver nanoparticles (AgNP) on microrhizome induction and antioxidant activity in C. caesia cultures. Field-grown C. caesia rhizomes extract was used in the green synthesis of AgNP. The synthesized AgNP was further characterized through scanning electron microscopy and X-ray diffraction. The AgNP, ranging from 0, 0.025, 0.05, 0.075 or 0.1 mg/l was supplemented in ½ strength liquid MS medium with 6% sucrose and 1 mg/l IBA. The MS medium with 0.05 mg/l AgNP found with significant morphological changes in C. caesia cultures (root number, root length and microrhizomes fresh weight). For the total phenolic and total terpenoids content estimation as well as for antioxidant activity analysis, the extracts of un-treated cultures (6% sucrose + 1 mg/l IBA, without AgNP), AgNP treated cultures (6% sucrose + 1 mg/l IBA with 0.025 and 0.05 mg/l AgNP) was used. The 0.025 and 0.05 mg/l AgNP enhanced the phenolic and terpenoid content in the cultures compared to the field-grown mother plant. The antioxidant activity of the cultures treated with AgNP also increased compared to un-treated cultures and field-grown mother plant. The Gas Chromatography-Mass Spectrometry (GC-MS) analysis revealed that the extract treated with 0.05 mg/l AgNP had increased production of monoterpene (camphor) and sesquiterpenes (β-elemenone and curcumenone). These increased terpenes could be responsible for the enhanced antioxidant activity of C. caesia cultures. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.52228/jrub.2024-37-1-2
Priyanka Chakradhari, A. Pati, A. Parganiha
Pit-building behavior in antlion larvae is a unique trait that ensures survival, growth, and metamorphosis. In the present study, we examined the 24-hour rhythm in the pit-building behavior of 16 antlion larvae collected from the PRSU campus, Raipur. We kept each larva individually in a plastic drinking cup in the laboratory. We observed the pit-building behavior of antlion larvae by monitoring two variables, i.e., the time lag for the initiation of pit reconstruction (TLIPR) and total time for pit construction (TTPC) after its demolition over three consecutive days, at four time points each day. We employed single Cosinor Rhythmometry to compute the characteristics of 24-hour rhythm in TLIPR and TTPC. We found a statistically significant 24-hour rhythm in both variables. We found the peaks of TLIPR between 14.32 h and 17.15 h, irrespective of days. Further, the factor 'time of the day' produced a statistically significant effect on the TLIPR and the maximum and minimum values were found at 14.00 h and 02.00 h, respectively. This implies that antlion larvae took time during the afternoon to initiate pit construction. This phenomenon was reversed during nighttime. TTPC exhibited a statistically significant 24-hour rhythm on day 3 and at the group level. We concluded that antlion larvae exhibit a 24-hour rhythm in pit-building behavior and are nocturnal as they initiate pit construction quickly at night.
{"title":"Time of the Day Variability in Pit-Building Behavior of Antlion Larvae","authors":"Priyanka Chakradhari, A. Pati, A. Parganiha","doi":"10.52228/jrub.2024-37-1-2","DOIUrl":"https://doi.org/10.52228/jrub.2024-37-1-2","url":null,"abstract":"\u0000 Pit-building behavior in antlion larvae is a unique trait that ensures survival, growth, and metamorphosis. In the present study, we examined the 24-hour rhythm in the pit-building behavior of 16 antlion larvae collected from the PRSU campus, Raipur. We kept each larva individually in a plastic drinking cup in the laboratory. We observed the pit-building behavior of antlion larvae by monitoring two variables, i.e., the time lag for the initiation of pit reconstruction (TLIPR) and total time for pit construction (TTPC) after its demolition over three consecutive days, at four time points each day. We employed single Cosinor Rhythmometry to compute the characteristics of 24-hour rhythm in TLIPR and TTPC. We found a statistically significant 24-hour rhythm in both variables. We found the peaks of TLIPR between 14.32 h and 17.15 h, irrespective of days. Further, the factor 'time of the day' produced a statistically significant effect on the TLIPR and the maximum and minimum values were found at 14.00 h and 02.00 h, respectively. This implies that antlion larvae took time during the afternoon to initiate pit construction. This phenomenon was reversed during nighttime. TTPC exhibited a statistically significant 24-hour rhythm on day 3 and at the group level. We concluded that antlion larvae exhibit a 24-hour rhythm in pit-building behavior and are nocturnal as they initiate pit construction quickly at night. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.52228/jrub.2024-37-1-8
Vyas Dubey, Reena Sonkar
In this article, an estimator of population variance using multi-auxiliary information has been proposed. It is seen that under certain conditions, the proposed estimator is less biased and more efficiency than existing estimators. Theoretical results are supported numerically. Moreover, a simulation study also has been made.
{"title":"An Estimator of Population Variance Using Multi-Auxiliary Information","authors":"Vyas Dubey, Reena Sonkar","doi":"10.52228/jrub.2024-37-1-8","DOIUrl":"https://doi.org/10.52228/jrub.2024-37-1-8","url":null,"abstract":"\u0000 In this article, an estimator of population variance using multi-auxiliary information has been proposed. It is seen that under certain conditions, the proposed estimator is less biased and more efficiency than existing estimators. Theoretical results are supported numerically. Moreover, a simulation study also has been made. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141013002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.52228/jrub.2024-37-1-9
Neha Mandle
The cornea, orbit, and other ocular tissues may get infected by fungi. Ophthalmic mycoses, often known as ocular fungal infections, are a significant cause of morbidity and blindness. For fungus infections, a brand-new azole derivative has been authorized. New immunological techniques would also be beneficial in the future for enhancing patient outcomes. Treatment of ocular illnesses presents a significant barrier in terms of getting medications into the eyes using traditional drug delivery methods, such as solutions. The main barriers are those between blood and the eyes, between lachrymal fluid and the eyes, and between medication losses from the ocular surface brought on by lachrymal fluid secretion. To increase the bioavailability and lengthen the residence duration of medications administered topically to the eye, a variety of ocular drug delivery carriers have been developed. The microemulsion is created using the PHASE TITRATION METHOD. Due to the dual hydrophilic and lipophilic properties of microemulsions, the loaded medications can diffuse passively and become significantly partitioned in the varying lipophilic-hydrophilic ocular barrier. This abstract will provide details on the microemulsions used to treat fungal infections of the eyes.
{"title":"Microemulsion as Novel Drug Delivery for Fungal Eye Infection","authors":"Neha Mandle","doi":"10.52228/jrub.2024-37-1-9","DOIUrl":"https://doi.org/10.52228/jrub.2024-37-1-9","url":null,"abstract":"\u0000 The cornea, orbit, and other ocular tissues may get infected by fungi. Ophthalmic mycoses, often known as ocular fungal infections, are a significant cause of morbidity and blindness. For fungus infections, a brand-new azole derivative has been authorized. New immunological techniques would also be beneficial in the future for enhancing patient outcomes. Treatment of ocular illnesses presents a significant barrier in terms of getting medications into the eyes using traditional drug delivery methods, such as solutions. The main barriers are those between blood and the eyes, between lachrymal fluid and the eyes, and between medication losses from the ocular surface brought on by lachrymal fluid secretion. To increase the bioavailability and lengthen the residence duration of medications administered topically to the eye, a variety of ocular drug delivery carriers have been developed. The microemulsion is created using the PHASE TITRATION METHOD. Due to the dual hydrophilic and lipophilic properties of microemulsions, the loaded medications can diffuse passively and become significantly partitioned in the varying lipophilic-hydrophilic ocular barrier. This abstract will provide details on the microemulsions used to treat fungal infections of the eyes. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.52228/jrub.2024-37-1-3
T. Kukreja, Arushi Saloki, S. Saraf
By definition, an open injury is any severe break in the continuity of the skin and deep tissue. Because contusions are healed injuries, the term given above does not apply to them. The classification of injuries is essential for both therapeutic and medico-legal purposes. Burn injuries are comparable to other injuries in that they require the same basic principles for healing and care, but they differ in that they have a greater impact on the patient's overall health and are essential to the patient's eventual survival, the development of deformity, and rehabilitation. Treatment of burn injuries has always been the responsibility of burn specialists. Both local and systemic therapy have long been advised for treating burn injuries and minimizing burn scars. This review summarizes the treatment of burn injuries brought on by a variety of physical and chemical agents requires unique regimens that are completely different from those used to treat any other traumatic injuries. Other acute injuries that undergo entire blood loss result in shock, but major burns that experience significant plasma loss due to increased capillary permeability result in distress. Burn injuries are initially sterile compared to the majority of other injuries, however, due to the immunocompromised state of burn patients and injury infection frequently ends in death in serious burns. We have discussed the pathophysiology, primary care therapies, nanomaterials used in injury healing therapy and various nanoparticles in injury healing process for burn injuries in this review.
{"title":"A Comprehensive Review of a particular Skin Injury: Pathogenesis, triggers, and current Treatment Options","authors":"T. Kukreja, Arushi Saloki, S. Saraf","doi":"10.52228/jrub.2024-37-1-3","DOIUrl":"https://doi.org/10.52228/jrub.2024-37-1-3","url":null,"abstract":"\u0000 By definition, an open injury is any severe break in the continuity of the skin and deep tissue. Because contusions are healed injuries, the term given above does not apply to them. The classification of injuries is essential for both therapeutic and medico-legal purposes. Burn injuries are comparable to other injuries in that they require the same basic principles for healing and care, but they differ in that they have a greater impact on the patient's overall health and are essential to the patient's eventual survival, the development of deformity, and rehabilitation. Treatment of burn injuries has always been the responsibility of burn specialists. Both local and systemic therapy have long been advised for treating burn injuries and minimizing burn scars. This review summarizes the treatment of burn injuries brought on by a variety of physical and chemical agents requires unique regimens that are completely different from those used to treat any other traumatic injuries. Other acute injuries that undergo entire blood loss result in shock, but major burns that experience significant plasma loss due to increased capillary permeability result in distress. Burn injuries are initially sterile compared to the majority of other injuries, however, due to the immunocompromised state of burn patients and injury infection frequently ends in death in serious burns. We have discussed the pathophysiology, primary care therapies, nanomaterials used in injury healing therapy and various nanoparticles in injury healing process for burn injuries in this review. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.52228/jrub.2024-37-1-7
Dipak Bej, N. K. Baghmar, Uma Gole
Soil is the protective skin of our earth's surface, but today’s numerous population pressures on land, along with industrialization, climatic variability such as a vigorous increase in temperature, acid rain, and deforestation, definitely degrade the quality of land. It should have to evaluate the quality of the land and find out the nutrition status as well as the soil health. The present study is employed in a Geographic Information System (GIS) environment to predict erosion risk using the Semi-Empirical Revised Soil Loss Erosion Model (RUSLE). The physiographic soil map has been prepared by visual interpretation of the Sentinal 2 satellite image, from which the soil erodibility factor has been derived. The digital elevation model (DEM) has been prepared from a contour map and used as the base map for the topographic-related analysis. In this model, the slope length (LS) factor has been prepared from the DEM. The crop conservation and management factor (C) and support practice factor (P) factors have been derived from the LULC map. It has been found that 4.45% of the watershed comes under very high erosion, 3.50% under high erosion, 7.80% under moderate erosion, 11.37% under low erosion, and 51.36% under a very low erosion-prone zone.
{"title":"Soil Erosion Risk Estimation by using Semi Empirical RUSLE model: A case study of Maniyari Basin, Chhattisgarh","authors":"Dipak Bej, N. K. Baghmar, Uma Gole","doi":"10.52228/jrub.2024-37-1-7","DOIUrl":"https://doi.org/10.52228/jrub.2024-37-1-7","url":null,"abstract":"\u0000 Soil is the protective skin of our earth's surface, but today’s numerous population pressures on land, along with industrialization, climatic variability such as a vigorous increase in temperature, acid rain, and deforestation, definitely degrade the quality of land. It should have to evaluate the quality of the land and find out the nutrition status as well as the soil health. The present study is employed in a Geographic Information System (GIS) environment to predict erosion risk using the Semi-Empirical Revised Soil Loss Erosion Model (RUSLE). The physiographic soil map has been prepared by visual interpretation of the Sentinal 2 satellite image, from which the soil erodibility factor has been derived. The digital elevation model (DEM) has been prepared from a contour map and used as the base map for the topographic-related analysis. In this model, the slope length (LS) factor has been prepared from the DEM. The crop conservation and management factor (C) and support practice factor (P) factors have been derived from the LULC map. It has been found that 4.45% of the watershed comes under very high erosion, 3.50% under high erosion, 7.80% under moderate erosion, 11.37% under low erosion, and 51.36% under a very low erosion-prone zone. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.52228/jrub.2024-37-1-6
Shubhra Sinha, M. Deb, Indrapal Karbhal, Suryakant Manikpuri, Rajiv Nayan, Babita Markande
The worldwide concern for environmental pollution, climate change and health hazards caused by various pollutants has significantly increased in the recent past. Various techniques have so far been employed for sensing applications of such organic as well as inorganic pollutants. Amongst the different techniques, surface enhanced infrared spectroscopy (SEIRS) is a powerful tool which is utilized for label-free and unambiguous identification of molecular species. SEIRS overcomes the limitations of the conventional infrared spectroscopy and has emerged as a potential technique with high surface sensitivity by enhancing the signals by many folds and also facilitates new studies from the fundamental aspect to applied sciences. The current review is dedicated to a comprehension of the SEIRS technique to provide a critical overview of its application as sensing probe for analysis of chemical species. The major features of Fourier Transform Infrared spectroscopy and SEIRS have been critically discussed.
{"title":"Basic and Advanced Logical Concept Derived from Surface Enhanced Infrared Spectroscopy (SEIRS) as Sensing Probe for Analysis of Chemical Species: A Brief Review","authors":"Shubhra Sinha, M. Deb, Indrapal Karbhal, Suryakant Manikpuri, Rajiv Nayan, Babita Markande","doi":"10.52228/jrub.2024-37-1-6","DOIUrl":"https://doi.org/10.52228/jrub.2024-37-1-6","url":null,"abstract":"\u0000 The worldwide concern for environmental pollution, climate change and health hazards caused by various pollutants has significantly increased in the recent past. Various techniques have so far been employed for sensing applications of such organic as well as inorganic pollutants. Amongst the different techniques, surface enhanced infrared spectroscopy (SEIRS) is a powerful tool which is utilized for label-free and unambiguous identification of molecular species. SEIRS overcomes the limitations of the conventional infrared spectroscopy and has emerged as a potential technique with high surface sensitivity by enhancing the signals by many folds and also facilitates new studies from the fundamental aspect to applied sciences. The current review is dedicated to a comprehension of the SEIRS technique to provide a critical overview of its application as sensing probe for analysis of chemical species. The major features of Fourier Transform Infrared spectroscopy and SEIRS have been critically discussed. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.52228/jrub.2024-37-1-1
Shradha Devi Dwivedi, Madhu Yadav, Deependra Singh, M. Singh
The utilization of customary methods for oral cleanliness maintenance has a long-written history. Herbs are making a comeback all over the world. Herbal extracts have been used in dentistry to alleviate pain as antimicrobial plaque specialists, to delay receptor arrival, and as germicides, cancer prevention agents, antimicrobials, antifungals, antibacterial, antiviral, and analgesics. Current article gives an outline of different natural products used in oral care with their impacts on oral health, restorative actions, applications, and marketed products. This article also highlights mechanistic need of oral cleanliness and the different dental diseases associated with it. The regular phytochemicals could offer a successful anti-microbial and address ways to deal with avoidance and restorative systems for different dental infections. There are different herbal formulations available on the market for oral care such as paste, mouthwash, gargles, gels, etc. creating need for awareness of consumers towards the herbal products. In these review, we have also discussed the commercial aspect of the herbal dental products along with assessment of side effects and toxicity of these herbs.
{"title":"Herbal Alternatives for Oral Health: Mechanistic Exploration with their Market Potential","authors":"Shradha Devi Dwivedi, Madhu Yadav, Deependra Singh, M. Singh","doi":"10.52228/jrub.2024-37-1-1","DOIUrl":"https://doi.org/10.52228/jrub.2024-37-1-1","url":null,"abstract":"\u0000 The utilization of customary methods for oral cleanliness maintenance has a long-written history. Herbs are making a comeback all over the world. Herbal extracts have been used in dentistry to alleviate pain as antimicrobial plaque specialists, to delay receptor arrival, and as germicides, cancer prevention agents, antimicrobials, antifungals, antibacterial, antiviral, and analgesics. Current article gives an outline of different natural products used in oral care with their impacts on oral health, restorative actions, applications, and marketed products. This article also highlights mechanistic need of oral cleanliness and the different dental diseases associated with it. The regular phytochemicals could offer a successful anti-microbial and address ways to deal with avoidance and restorative systems for different dental infections. There are different herbal formulations available on the market for oral care such as paste, mouthwash, gargles, gels, etc. creating need for awareness of consumers towards the herbal products. In these review, we have also discussed the commercial aspect of the herbal dental products along with assessment of side effects and toxicity of these herbs. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atopic Dermatitis (AD) is a complicated condition that places tremendous physiological and psychological strain on individuals. Natural products have long been used to cure diseases such as cancer, asthma, gastrointestinal disorders, neurological disorders, and infections. The study findings reveal that natural compounds, particularly quercetin, gallic acid, and ginsenosides, have promised preventive effects against atopic dermatitis. The study addresses the medicinal properties of bioactive compounds and emphasizes their ability to exert anti-inflammatory action. These compounds exhibit anti-inflammatory properties by reducing the quantity and functionality of various inflammatory cells such as cytokines neutrophils, monocytes, lymphocytes, Langerhans cells, interleukins (ILs, such as IL-1 IL-5, and IL-4, IL-13, and IL-31), TNF-α, TSLP, and IgE, etc. The studies would pave the way for the development of natural compounds specifically designed to treat atopic dermatitis in humans. Atopic dermatitis is routinely treated using bioactive and phytoconstituents derived from them. As a result, the review emphasizes recent advances in understanding the clinical characteristics, etiology, pathogenesis, treatment with bioactive compounds, and management of atopic dermatitis.
{"title":"Potential of Bioactive Compounds for Atopic Dermatitis","authors":"Ankita Sahu, Manju Singh, Vishal Jain, Veenu Joshi, Amber Vyas","doi":"10.52228/jrub.2023-36-2-1","DOIUrl":"https://doi.org/10.52228/jrub.2023-36-2-1","url":null,"abstract":"Atopic Dermatitis (AD) is a complicated condition that places tremendous physiological and psychological strain on individuals. Natural products have long been used to cure diseases such as cancer, asthma, gastrointestinal disorders, neurological disorders, and infections. The study findings reveal that natural compounds, particularly quercetin, gallic acid, and ginsenosides, have promised preventive effects against atopic dermatitis. The study addresses the medicinal properties of bioactive compounds and emphasizes their ability to exert anti-inflammatory action. These compounds exhibit anti-inflammatory properties by reducing the quantity and functionality of various inflammatory cells such as cytokines neutrophils, monocytes, lymphocytes, Langerhans cells, interleukins (ILs, such as IL-1 IL-5, and IL-4, IL-13, and IL-31), TNF-α, TSLP, and IgE, etc. The studies would pave the way for the development of natural compounds specifically designed to treat atopic dermatitis in humans. Atopic dermatitis is routinely treated using bioactive and phytoconstituents derived from them. As a result, the review emphasizes recent advances in understanding the clinical characteristics, etiology, pathogenesis, treatment with bioactive compounds, and management of atopic dermatitis.","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139132762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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