Pub Date : 2023-07-13DOI: 10.52228/jrub.2023-36-1-1
N. Shweta, Jaswani Kamal, S. Keshavkant
Chlorpyrifos is a popularly used organophosphate and has immense agricultural applications. It is one of the major causes of soil contamination due to its higher adsorption coefficient, hydrophobicity and relatively longer persistence. Conducted study was attempted to monitor responses of Bacillus megaterium, isolated from the paddy growing agricultural field towards different doses of chlorpyrifos. The results highlighted the tolerance of this bacterium to higher concentration (800 mg L-1) of chlorpyrifos. However, protein is an important macromolecule in any living cells and is representative of all the important functions going inside the cell. Thus, quantification and profiling of protein of this bacterium in response to different doses of chlorpyrifos would probably decipher expression, if any, of stress responsive gene(s). The overall findings revealed that Bacillus megaterium expressed a few enzymes/ or proteins in order to show adaptation towards surrounding environment. It can be an efficient degrader of chlorpyrifos, hence, could be exploited for remediation of chlorpyrifos contaminated sites.
{"title":"Chlorpyrifos Mediated Amendment in Protein Profiling of Bacillus spp.","authors":"N. Shweta, Jaswani Kamal, S. Keshavkant","doi":"10.52228/jrub.2023-36-1-1","DOIUrl":"https://doi.org/10.52228/jrub.2023-36-1-1","url":null,"abstract":"\u0000 Chlorpyrifos is a popularly used organophosphate and has immense agricultural applications. It is one of the major causes of soil contamination due to its higher adsorption coefficient, hydrophobicity and relatively longer persistence. Conducted study was attempted to monitor responses of Bacillus megaterium, isolated from the paddy growing agricultural field towards different doses of chlorpyrifos. The results highlighted the tolerance of this bacterium to higher concentration (800 mg L-1) of chlorpyrifos. However, protein is an important macromolecule in any living cells and is representative of all the important functions going inside the cell. Thus, quantification and profiling of protein of this bacterium in response to different doses of chlorpyrifos would probably decipher expression, if any, of stress responsive gene(s). The overall findings revealed that Bacillus megaterium expressed a few enzymes/ or proteins in order to show adaptation towards surrounding environment. It can be an efficient degrader of chlorpyrifos, hence, could be exploited for remediation of chlorpyrifos contaminated sites. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74538385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.52228/jrub.2023-36-1-5
Shraddha Sharma
With the rapid growth in the urbanization of Chhattisgarh, the need for sustainability has also brought out various strategies for catering to the issue of mass fossil usage. One such way can be seen in creating neighborhoods and environments that engage in practices that encourage sustainable living. Another is the usage of a technique that measures the amount of energy a commodity takes to produce to be put into use, followed by its maintenance and end of life. Life cycle analysis (LCA) is a technique used to understand the amount of energy that has surpassed the initial production of any product to its final disposal stage. This was brought out for the sole purpose of utilizing and opting for products that possess low embodied energy- an attempt to sensitize people to sustainability. Over the years the phases and the scale for LCA have changed drastically. This paper focuses on how the life cycle analysis could contribute to developing an environment for people that portrays sustainability in Chhattisgarh. A sustainable community is a way ahead for a better future and by integrating LCA for creating a sustainable community in the Indian context, a holistic approach could be envisaged that delivers the aim to be environmentally, economically, and socially sustainable.
{"title":"Exploring Life Cycle Analysis in Developing Sustainable Communities in Chhattisgarh","authors":"Shraddha Sharma","doi":"10.52228/jrub.2023-36-1-5","DOIUrl":"https://doi.org/10.52228/jrub.2023-36-1-5","url":null,"abstract":"\u0000 With the rapid growth in the urbanization of Chhattisgarh, the need for sustainability has also brought out various strategies for catering to the issue of mass fossil usage. One such way can be seen in creating neighborhoods and environments that engage in practices that encourage sustainable living. Another is the usage of a technique that measures the amount of energy a commodity takes to produce to be put into use, followed by its maintenance and end of life. Life cycle analysis (LCA) is a technique used to understand the amount of energy that has surpassed the initial production of any product to its final disposal stage. This was brought out for the sole purpose of utilizing and opting for products that possess low embodied energy- an attempt to sensitize people to sustainability. Over the years the phases and the scale for LCA have changed drastically. This paper focuses on how the life cycle analysis could contribute to developing an environment for people that portrays sustainability in Chhattisgarh. A sustainable community is a way ahead for a better future and by integrating LCA for creating a sustainable community in the Indian context, a holistic approach could be envisaged that delivers the aim to be environmentally, economically, and socially sustainable. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88472180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.52228/jrub.2023-36-1-6
Keshar Verma, Sudheer Bhoi, Yash Parhad, M. Deb
Cement manufacturing Industries is one of the key sectors of the Indian Economy which has been rapidly growing at a rate over 8% and it is estimated to grow more. Balodabazar is known as the Cement Hub of Chhattisgarh, most of the cement industries are running in Balodabazar district of Chhattisgarh. They use plenty of water for the cooling processes at the time of cement manufacturing and discharging effluents into streams and rivers by polluting nearby water resources. In this work, the waste water quality assessment study is attempted by examining the physic-chemical parameters viz. Temperature, pH, Electrical Conductivity (EC), TDS, DO, Total hardness, Na+, K+, Ca2+, Mg2+, CL-, SO42-, NO3-, and PO43-and also analysis of heavy metal element (lead) is described. The abundance of cations and anions in the analyzed waste water sample is Ca (%)>Mg (%)>Na (%)> K (%) and SO42-(%)>Cl- (%)>NO3- (%)> PO43- (%) respectively. The waste water is found to be acidic in nature and out of 17 samples 6-7 samples are contaminated by lead. It is inferred that the study area is moderately suitable. Almost all water bodies in India have been found to be contaminated by industrial activities. Although the CPCB’s strict guidelines apply to all industries in India, the current state of the environment is far from ideal.
{"title":"Monitoring the Concentration of Lead in the Industrial Wastewater of Baloda Bazar District","authors":"Keshar Verma, Sudheer Bhoi, Yash Parhad, M. Deb","doi":"10.52228/jrub.2023-36-1-6","DOIUrl":"https://doi.org/10.52228/jrub.2023-36-1-6","url":null,"abstract":"\u0000 Cement manufacturing Industries is one of the key sectors of the Indian Economy which has been rapidly growing at a rate over 8% and it is estimated to grow more. Balodabazar is known as the Cement Hub of Chhattisgarh, most of the cement industries are running in Balodabazar district of Chhattisgarh. They use plenty of water for the cooling processes at the time of cement manufacturing and discharging effluents into streams and rivers by polluting nearby water resources. In this work, the waste water quality assessment study is attempted by examining the physic-chemical parameters viz. Temperature, pH, Electrical Conductivity (EC), TDS, DO, Total hardness, Na+, K+, Ca2+, Mg2+, CL-, SO42-, NO3-, and PO43-and also analysis of heavy metal element (lead) is described. The abundance of cations and anions in the analyzed waste water sample is Ca (%)>Mg (%)>Na (%)> K (%) and SO42-(%)>Cl- (%)>NO3- (%)> PO43- (%) respectively. The waste water is found to be acidic in nature and out of 17 samples 6-7 samples are contaminated by lead. It is inferred that the study area is moderately suitable. Almost all water bodies in India have been found to be contaminated by industrial activities. Although the CPCB’s strict guidelines apply to all industries in India, the current state of the environment is far from ideal. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87524096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.52228/jrub.2023-36-1-10
D. Sahu, D. P. Bisen, N. Brahme, Kanchan Tiwari, Aastha Sahu
In this paper, Eu3+ doped phosphor Li4SrCa(SiO4)2 is successfully synthesized via a solid-state reaction method at high temperatures. Structure characterization is determined using X-ray diffraction (XRD). Surface morphology was analyzed using Field emission scanning electron microscopy(FESEM). The EDX spectra confirm the elements present in Li4SrCa(SiO4)2:Eu3+ phosphor. Photoluminescence(PL) spectra of Li4SrCa(SiO4)2:Eu3+ phosphor was efficiently excited by UV range 220-450nm and under the excitation 395nm phosphors shows good intensity with an orange-red intense peak at 591nm and 619 nm was due to 4D0-7F1 and 4D0-7F2 transition respectively. Commission International del’ Eclairage (CIE) color coordinate was calculated, which confirms the Eu3+ doped phosphor with a CIE value of (x=0.6259, y=0.3737). This phosphor is considered to be a new promising orange-red emitting phosphor for WLEDs application. This phosphor may be used for solid-state lighting.
本文采用固相反应方法，在高温下成功合成了Eu3+掺杂的荧光粉Li4SrCa(SiO4)2。结构表征采用x射线衍射(XRD)确定。利用场发射扫描电镜(FESEM)分析了表面形貌。EDX光谱证实了Li4SrCa(SiO4)2:Eu3+荧光粉中存在的元素。Li4SrCa(SiO4)2:Eu3+荧光粉的光致发光光谱在220 ~ 450nm范围内被有效激发，在395nm激发下荧光粉表现出良好的光致发光强度，在591nm和619nm处分别由于4D0-7F1和4D0-7F2跃迁而出现橘红色的光致发光峰。计算了CIE (Commission International del’Eclairage)颜色坐标，确认了Eu3+掺杂荧光粉的CIE值为(x=0.6259, y=0.3737)。该荧光粉被认为是一种具有较好应用前景的橙红色发光荧光粉。这种荧光粉可用于固态照明。
{"title":"Structural, Compositional and Photoluminescence Studies of Li4SrCa(SiO4)2: Eu3+ Red Phosphor Synthesized by Solid State Reaction Method","authors":"D. Sahu, D. P. Bisen, N. Brahme, Kanchan Tiwari, Aastha Sahu","doi":"10.52228/jrub.2023-36-1-10","DOIUrl":"https://doi.org/10.52228/jrub.2023-36-1-10","url":null,"abstract":"\u0000 In this paper, Eu3+ doped phosphor Li4SrCa(SiO4)2 is successfully synthesized via a solid-state reaction method at high temperatures. Structure characterization is determined using X-ray diffraction (XRD). Surface morphology was analyzed using Field emission scanning electron microscopy(FESEM). The EDX spectra confirm the elements present in Li4SrCa(SiO4)2:Eu3+ phosphor. Photoluminescence(PL) spectra of Li4SrCa(SiO4)2:Eu3+ phosphor was efficiently excited by UV range 220-450nm and under the excitation 395nm phosphors shows good intensity with an orange-red intense peak at 591nm and 619 nm was due to 4D0-7F1 and 4D0-7F2 transition respectively. Commission International del’ Eclairage (CIE) color coordinate was calculated, which confirms the Eu3+ doped phosphor with a CIE value of (x=0.6259, y=0.3737). This phosphor is considered to be a new promising orange-red emitting phosphor for WLEDs application. This phosphor may be used for solid-state lighting. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80452607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.52228/jrub.2023-36-1-4
Nafisha Parveen, N. Gurwara
This study examines the impact of lifestyle modification counselling on the weight status of non-alcoholic liver disease patients. To conduct the study 300 newly diagnosed male liver disease patients were selected as samples and randomly placed into experimental and control group. The study area of this study was the Raipur district of Chhattisgarh. The standard anthropometric test was used for the assessment of height and weight and BMI was calculated using a formula. Three months counselling program was prepared based on the Fantastic Lifestyle Assessment Checklist. Results reveal that in the pre-test assessment, 22.7% of male liver disease patients lie in the normal weight category whereas after three months of lifestyle counselling the percentage increased to 26.7%. In the pre-test assessment of male liver disease patients in the control group, 12.7% were normal weight and this percentage remained unchanged in the post-test assessment. It has been reported that even slight weight loss due to positive lifestyle changes improves the condition of non-alcoholic liver disease patients hence the results of this study have magnanimous importance towards the management of non-alcoholic liver disease patients.
{"title":"Lifestyle Modification Therapy and its Effect on Weight Status of Non-Alcoholic Male Liver Disease Patients","authors":"Nafisha Parveen, N. Gurwara","doi":"10.52228/jrub.2023-36-1-4","DOIUrl":"https://doi.org/10.52228/jrub.2023-36-1-4","url":null,"abstract":"\u0000 This study examines the impact of lifestyle modification counselling on the weight status of non-alcoholic liver disease patients. To conduct the study 300 newly diagnosed male liver disease patients were selected as samples and randomly placed into experimental and control group. The study area of this study was the Raipur district of Chhattisgarh. The standard anthropometric test was used for the assessment of height and weight and BMI was calculated using a formula. Three months counselling program was prepared based on the Fantastic Lifestyle Assessment Checklist. Results reveal that in the pre-test assessment, 22.7% of male liver disease patients lie in the normal weight category whereas after three months of lifestyle counselling the percentage increased to 26.7%. In the pre-test assessment of male liver disease patients in the control group, 12.7% were normal weight and this percentage remained unchanged in the post-test assessment. It has been reported that even slight weight loss due to positive lifestyle changes improves the condition of non-alcoholic liver disease patients hence the results of this study have magnanimous importance towards the management of non-alcoholic liver disease patients. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87382875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.52228/jrub.2023-36-1-2
Kokila Bharti Jaiswal
Mortality rate in Chhattisgarh state due to ischemic heart disease is 43.6% and growing exponentially every year. Early detection of cardiac health plays a major role in decreasing this rate. Due to the insufficient hospitals and accessibility of the dedicated equipment, remote health monitoring has become quite inevitable after SARC-CoV-2 pandemic. Due to its excellent capability is it going to be cardiac rate measurement method of future. However, the difficulty in HR measurement is that, it gets affected with noise very easily because the amplitude of physiological signal is very weak. remote Photoplethysmography (rPPG) is a technique to measure the cardiac activity in a contact-less manner using digital cameras. However, the HR estimation suffers from two major artifacts, motion artifact and illumination artifact. Denoising of rPPG signal is a fundamental problem and needs to be addressed very carefully. In this article we have proposed a novel HR estimation network using a combination of wavelet decomposition and Convolutional Neural Network (CNN). This approach provides distinct features at different frequency levels, which facilitates the removal of noisy signal. Performance evaluation of the proposed method is done on self-collected dataset. Lower values of RMSE and MAE proves the efficacy of the proposed method.
{"title":"Development of Non-Invasive Technique for Heart Rate Detection Using Facial Videos","authors":"Kokila Bharti Jaiswal","doi":"10.52228/jrub.2023-36-1-2","DOIUrl":"https://doi.org/10.52228/jrub.2023-36-1-2","url":null,"abstract":"\u0000 Mortality rate in Chhattisgarh state due to ischemic heart disease is 43.6% and growing exponentially every year. Early detection of cardiac health plays a major role in decreasing this rate. Due to the insufficient hospitals and accessibility of the dedicated equipment, remote health monitoring has become quite inevitable after SARC-CoV-2 pandemic. Due to its excellent capability is it going to be cardiac rate measurement method of future. However, the difficulty in HR measurement is that, it gets affected with noise very easily because the amplitude of physiological signal is very weak. remote Photoplethysmography (rPPG) is a technique to measure the cardiac activity in a contact-less manner using digital cameras. However, the HR estimation suffers from two major artifacts, motion artifact and illumination artifact. Denoising of rPPG signal is a fundamental problem and needs to be addressed very carefully. In this article we have proposed a novel HR estimation network using a combination of wavelet decomposition and Convolutional Neural Network (CNN). This approach provides distinct features at different frequency levels, which facilitates the removal of noisy signal. Performance evaluation of the proposed method is done on self-collected dataset. Lower values of RMSE and MAE proves the efficacy of the proposed method. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85676040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.52228/jrub.2023-36-1-9
N. Sahu, Sukrita Shriwas, Yeendeswari Gendre, Aakanksha Sinha, S. Daharwal
Naproxen is a Nonsteroidal Anti-Inflammatory Drug (NSAID). It is mostly used to treat pain or inflammation caused by conditions such as arthritis, gout, tendinitis or menstrual cramps. Naproxen is available in isolated dose with various similar anti-inflammatory drugs, i.e.; esomeprazole, pantoprazole, paracetamol, ranitidine, sumatriptan and ibuprofen. This survey evaluates various methods for the analysis of Naproxen in bulk drugs and formulated products. Analytical procedures are critical for determining compositions, they allow as to obtain both qualitative and quantitative results utilizing by the advanced analytical tools. This include HPLC, HPTLC, UV- spectrophotometry, capillary electrophoresis, and electrochemical meth-ods. The UV-spectrophotometry method is applied for the investigation of Naproxen in biologi-cal media, bulk samples and in various dosage formulations. The HPLC technique of Naproxen alone and the combination, including parameters such as matrix, stationary phase, mobile phase, wavelength detection, etc. HPTLC method parameters such as stationary phase, mobile combi-nation phase, RF value, etc. To maintain high commercial product quality standards and to ad-here to regulatory requirements, analytical technique development is necessary. Drug concen-trations are measured using bioanalytical techniques. Development and validation of bioanalyt-ical method is important to understand the pharmacokinetics of any drug and/or its metabolites.
{"title":"A Review on Various Analytical Methodologies of Naproxen","authors":"N. Sahu, Sukrita Shriwas, Yeendeswari Gendre, Aakanksha Sinha, S. Daharwal","doi":"10.52228/jrub.2023-36-1-9","DOIUrl":"https://doi.org/10.52228/jrub.2023-36-1-9","url":null,"abstract":"\u0000 Naproxen is a Nonsteroidal Anti-Inflammatory Drug (NSAID). It is mostly used to treat pain or inflammation caused by conditions such as arthritis, gout, tendinitis or menstrual cramps. Naproxen is available in isolated dose with various similar anti-inflammatory drugs, i.e.; esomeprazole, pantoprazole, paracetamol, ranitidine, sumatriptan and ibuprofen. This survey evaluates various methods for the analysis of Naproxen in bulk drugs and formulated products. Analytical procedures are critical for determining compositions, they allow as to obtain both qualitative and quantitative results utilizing by the advanced analytical tools. This include HPLC, HPTLC, UV- spectrophotometry, capillary electrophoresis, and electrochemical meth-ods. The UV-spectrophotometry method is applied for the investigation of Naproxen in biologi-cal media, bulk samples and in various dosage formulations. The HPLC technique of Naproxen alone and the combination, including parameters such as matrix, stationary phase, mobile phase, wavelength detection, etc. HPTLC method parameters such as stationary phase, mobile combi-nation phase, RF value, etc. To maintain high commercial product quality standards and to ad-here to regulatory requirements, analytical technique development is necessary. Drug concen-trations are measured using bioanalytical techniques. Development and validation of bioanalyt-ical method is important to understand the pharmacokinetics of any drug and/or its metabolites. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73306321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.52228/jrub.2023-36-1-7
Devendra Kumar Kurrey, H. Pathak
Agriculture and forest product collection are the economic foundations of the Bastar district. Paddy and maize are widely grown in the Bastar region. Paddy is grown in 76 percent of the gross cropped area in Bastar district. To assess the impact of climate change on paddy productivity a simple ordinary least square (OLS) Regression analysis have been analysed. Observation revealed that the rainfall during the month of June to September affected the crop yield positively, Monsoon rainfall affects more the crop yield negatively. Bastar district is mainly rainfed and only 2.14 percent area near to the water resources can be irrigated, the lack of irrigation effects the crop yield greatly hence, any increase in rainfall in the germination and booting period (June to August) will help in increase the productivity of crop. The month of or before harvesting if gets rain, it can destroy the standing crop and cause huge lose to the production.An increase in annual maximum Temperature affects the paddy crop productivity negatively whereas productivity increases with every per cent increase with the annual minimum Temperature. Paddy is a tropical and subtropical crop hence, the result had positive relationship with maximum Temperature, Excessive rainfall can negatively or positively impact crop yield.The study suggests to develop such varieties which can withstand with minimum Temperature.
{"title":"Impact of Climate Change on Paddy Yield in Bastar District of Chhattisgarh","authors":"Devendra Kumar Kurrey, H. Pathak","doi":"10.52228/jrub.2023-36-1-7","DOIUrl":"https://doi.org/10.52228/jrub.2023-36-1-7","url":null,"abstract":"\u0000 Agriculture and forest product collection are the economic foundations of the Bastar district. Paddy and maize are widely grown in the Bastar region. Paddy is grown in 76 percent of the gross cropped area in Bastar district. To assess the impact of climate change on paddy productivity a simple ordinary least square (OLS) Regression analysis have been analysed. Observation revealed that the rainfall during the month of June to September affected the crop yield positively, Monsoon rainfall affects more the crop yield negatively. Bastar district is mainly rainfed and only 2.14 percent area near to the water resources can be irrigated, the lack of irrigation effects the crop yield greatly hence, any increase in rainfall in the germination and booting period (June to August) will help in increase the productivity of crop. The month of or before harvesting if gets rain, it can destroy the standing crop and cause huge lose to the production.An increase in annual maximum Temperature affects the paddy crop productivity negatively whereas productivity increases with every per cent increase with the annual minimum Temperature. Paddy is a tropical and subtropical crop hence, the result had positive relationship with maximum Temperature, Excessive rainfall can negatively or positively impact crop yield.The study suggests to develop such varieties which can withstand with minimum Temperature. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81212187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.52228/jrub.2023-36-1-11
S. Gaikwad, Preeti K. Suresh
Background: Magnetically Responsive Mesalamine Microspheres is an effective strategy for localized drug delivery only at the target site for the treatment of Irritable Bowel Diseases and thereby minimizing the dose and drug induced toxicity. Objective: The main objective of the study is to localize the drug only at the target site thereby minimizing the dose. Result and Discussion: 1. The aim of present study was to formulate Magnetically Responsive Mesalamine Microspheres by solvent evaporation method using biodegradable polymers Chitosan and Pectin and carry out the various pharmaceutical and magnetic characterizations, to study the effect of polymer type on in-vitro drug release and preclinical in-vitro screening studies such as in- vitro release studies using microflora activated system and in-vitro anti-inflammatory activity. 2. Chemical compatibility study was performed using FTIR spectroscopy. FTIR spectroscopy studies indicated that the Mesalamine is compatible with polymers. The spectra showed no changes in the major peaks thus confirming no interactions between drug and polymers. 3. Calibration curves of Mesalamine was constructed in Phosphate Buffer Saline pH7. 4. Magnetite (Fe3O4) (used as magnetic carrier) was chemically synthesized using precipitation method.5. In the present study, 3 formulations were prepared in total by using Chitosan and Pectin as polymer in different ratios (1:1,1:2 and 1:3) of each polymer and combination of two polymers. Also, the effect of polymer type was studied. Conclusion: It can be concluded that the Magnetically Responsive Mesalamine Microspheres offer a localized drug delivery only at the target site by the combined effect of physical approach (utilizing the principle of magnetic targeting with an intention to produce a depot near the target organ) and biochemical approach (using biodegradable polymers chitosan and pectin for drug release in a controlled manner). By producing a depot near the target organ, unwanted distribution of drug to non-target organ can be avoided.
{"title":"Formulation and Characterization of Magnetically Responsive Mesalamine Microspheres for Colon Targeting","authors":"S. Gaikwad, Preeti K. Suresh","doi":"10.52228/jrub.2023-36-1-11","DOIUrl":"https://doi.org/10.52228/jrub.2023-36-1-11","url":null,"abstract":"\u0000 Background: Magnetically Responsive Mesalamine Microspheres is an effective strategy for localized drug delivery only at the target site for the treatment of Irritable Bowel Diseases and thereby minimizing the dose and drug induced toxicity. \u0000Objective: The main objective of the study is to localize the drug only at the target site thereby minimizing the dose.\u0000Result and Discussion: 1. The aim of present study was to formulate Magnetically Responsive Mesalamine Microspheres by solvent evaporation method using biodegradable polymers Chitosan and Pectin and carry out the various pharmaceutical and magnetic characterizations, to study the effect of polymer type on in-vitro drug release and preclinical in-vitro screening studies such as in- vitro release studies using microflora activated system and in-vitro anti-inflammatory activity. 2. Chemical compatibility study was performed using FTIR spectroscopy. FTIR spectroscopy studies indicated that the Mesalamine is compatible with polymers. The spectra showed no changes in the major peaks thus confirming no interactions between drug and polymers. 3. Calibration curves of Mesalamine was constructed in Phosphate Buffer Saline pH7. 4. Magnetite (Fe3O4) (used as magnetic carrier) was chemically synthesized using precipitation method.5. In the present study, 3 formulations were prepared in total by using Chitosan and Pectin as polymer in different ratios (1:1,1:2 and 1:3) of each polymer and combination of two polymers. Also, the effect of polymer type was studied.\u0000Conclusion: It can be concluded that the Magnetically Responsive Mesalamine Microspheres offer a localized drug delivery only at the target site by the combined effect of physical approach (utilizing the principle of magnetic targeting with an intention to produce a depot near the target organ) and biochemical approach (using biodegradable polymers chitosan and pectin for drug release in a controlled manner). By producing a depot near the target organ, unwanted distribution of drug to non-target organ can be avoided. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75342078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-02DOI: 10.52228/jrub.2023-35-2-2
T. Kukreja, S. Saraf
Itraconazole is a triazole antifungal agent that is synthesised. Itraconazole has been manufactured into a variety of pharmacological formulations and administered by a variety of ways. Itraconazole pills are used to treat pulmonary fungal infections that can spread throughout the body. Because Itraconazole is not yet officially listed in any pharmacopoeia, only a few procedures for quality control and stability testing in pharmaceutical formulations have been published. The development of itraconazole-loaded nanostructured lipid carriers (ITZ-NLC). Itraconazole NLC have been successfully developed. Itraconazole topical NLC developed for the treatment of onychomycosis does not exist, according to my survey.The development and evaluation of stable itraconazole topical gel formulations proved successful. Itraconazole NLC was produced utilising the microemulsion method, indicating the viability of adopting this method as a continuous manufacturing tool for NLC formulation. Further, the ITZ- NLC was incorporated in the gelling agent and we evaluated it under specific parameters.
{"title":"Formulation of Topical Itraconazole Nanostructured Lipid Carriers (Nlc) Gel for Onychomycosis","authors":"T. Kukreja, S. Saraf","doi":"10.52228/jrub.2023-35-2-2","DOIUrl":"https://doi.org/10.52228/jrub.2023-35-2-2","url":null,"abstract":"\u0000 Itraconazole is a triazole antifungal agent that is synthesised. Itraconazole has been manufactured into a variety of pharmacological formulations and administered by a variety of ways. Itraconazole pills are used to treat pulmonary fungal infections that can spread throughout the body. Because Itraconazole is not yet officially listed in any pharmacopoeia, only a few procedures for quality control and stability testing in pharmaceutical formulations have been published. The development of itraconazole-loaded nanostructured lipid carriers (ITZ-NLC). Itraconazole NLC have been successfully developed. Itraconazole topical NLC developed for the treatment of onychomycosis does not exist, according to my survey.The development and evaluation of stable itraconazole topical gel formulations proved successful. Itraconazole NLC was produced utilising the microemulsion method, indicating the viability of adopting this method as a continuous manufacturing tool for NLC formulation. Further, the ITZ- NLC was incorporated in the gelling agent and we evaluated it under specific parameters. \u0000","PeriodicalId":17214,"journal":{"name":"Journal of Ravishankar University (PART-B)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83932142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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