Pub Date : 2023-01-01DOI: 10.52568/001193/jcsp/45.01.2023
Mohamed Abdesselem Dems
We present here a study based on Density Functional Theory (DFT) calculations, to contribute to the understanding of the complexes behavior based on tungsten carbonyls ([W(C7H7NS)(CO)5], [W ( C3H6N2S)(CO)5 ] ), which consider as targets molecules of biological interest and easily detectable probes by IR spectroscopy. The results showed good agreements between the calculated and experimental values of the geometric parameters for the two complexes. A peak in the IR spectrum at 2030 cm-1 is due to the stretching of the C-O triple bond, according to the AIM analysis (0.07 andlt;ρ andlt;0.15 ), the existence of an intermediate interaction between the tungsten and the CO ligand. Moreover, these complexes are stable, the spectra of TD–DFT analysis showed these complexes absorb in the same domain of wavelengths, through absorption features at about 110-160 nm, characterized by natural transitions of HOMO/LUMO; of type MLCT for both complexes
{"title":"TDDFT-DFT Theoretical Method and Topological Analysis to the Behavior Understanding of Two Tungsten Carbonyl Complexes","authors":"Mohamed Abdesselem Dems","doi":"10.52568/001193/jcsp/45.01.2023","DOIUrl":"https://doi.org/10.52568/001193/jcsp/45.01.2023","url":null,"abstract":"We present here a study based on Density Functional Theory (DFT) calculations, to contribute to the understanding of the complexes behavior based on tungsten carbonyls ([W(C7H7NS)(CO)5], [W ( C3H6N2S)(CO)5 ] ), which consider as targets molecules of biological interest and easily detectable probes by IR spectroscopy. The results showed good agreements between the calculated and experimental values of the geometric parameters for the two complexes. A peak in the IR spectrum at 2030 cm-1 is due to the stretching of the C-O triple bond, according to the AIM analysis (0.07 andlt;ρ andlt;0.15 ), the existence of an intermediate interaction between the tungsten and the CO ligand. Moreover, these complexes are stable, the spectra of TD–DFT analysis showed these complexes absorb in the same domain of wavelengths, through absorption features at about 110-160 nm, characterized by natural transitions of HOMO/LUMO; of type MLCT for both complexes","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70707596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.52568/0012172/jcsp/45.02.2023
M. mer ERT RK, Elif L Elif L, Melek OL Ayvaz and Emine BA Datli Melek OL AYVAZ and Emine BA DATLI
In this study, bioactive properties and GC-MS analyses of the Camellia sinensis (seed, leaf, and blossom parts) and commercial black tea extracts were compared. The total phenolic content (TPC) and antioxidant and antimicrobial activities of extracts were determined. The gas Chromatography-Mass Spectrometry (GC-MS) technique was used to identify the major bioactive compounds in extracts. The TPC and antioxidant activity values of the alcohol extract prepared from the leaf part of the C. sinensis are higher than the other extracts. There was a strong correlation between total phenolic content and antioxidant amount among the ethanol extracts of C. sinensis. In antimicrobial evaluation, the ethanol extracts showed more activity; the ethanolic extract of C. sinensis seeds was the most effective. GC-MS results indicated various organic compounds in the C. sinensis extracts, mainly saturated and unsaturated aromatic esters, aromatic alcohols, some cyclic structures, aromatic amine, and boranic esters with different therapeutic activities. The black tea extracts exhibited a more straightforward variety of bio components as aromatic esters and boranic ester. According to the obtained results, C. sinensis and black tea extracts would exert several beneficial effects by their biological activities thanks to the possible synergistic effect of chemical contents detected by GC-MS analysis. However, GC-MS results indicated that the black tea sample had much fewer bioconstituents than fresh C. sinensis plant samples.
{"title":"Comparison of Biological Activities and Bioactive Components of Seed, Leaf, and Blossom Parts of Camellia sinensis (L.) Kuntze and Commercial Black Tea","authors":"M. mer ERT RK, Elif L Elif L, Melek OL Ayvaz and Emine BA Datli Melek OL AYVAZ and Emine BA DATLI","doi":"10.52568/0012172/jcsp/45.02.2023","DOIUrl":"https://doi.org/10.52568/0012172/jcsp/45.02.2023","url":null,"abstract":"In this study, bioactive properties and GC-MS analyses of the Camellia sinensis (seed, leaf, and blossom parts) and commercial black tea extracts were compared. The total phenolic content (TPC) and antioxidant and antimicrobial activities of extracts were determined. The gas Chromatography-Mass Spectrometry (GC-MS) technique was used to identify the major bioactive compounds in extracts. The TPC and antioxidant activity values of the alcohol extract prepared from the leaf part of the C. sinensis are higher than the other extracts. There was a strong correlation between total phenolic content and antioxidant amount among the ethanol extracts of C. sinensis. In antimicrobial evaluation, the ethanol extracts showed more activity; the ethanolic extract of C. sinensis seeds was the most effective. GC-MS results indicated various organic compounds in the C. sinensis extracts, mainly saturated and unsaturated aromatic esters, aromatic alcohols, some cyclic structures, aromatic amine, and boranic esters with different therapeutic activities. The black tea extracts exhibited a more straightforward variety of bio components as aromatic esters and boranic ester. According to the obtained results, C. sinensis and black tea extracts would exert several beneficial effects by their biological activities thanks to the possible synergistic effect of chemical contents detected by GC-MS analysis. However, GC-MS results indicated that the black tea sample had much fewer bioconstituents than fresh C. sinensis plant samples.","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70708084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.52568/001241/jcsp/45.03.2023
Milena Miljkovi Milena Miljkovi, Sandra S Konstantinovi Sandra S Konstantinovi, Vojkan M Miljkovi Vojkan M Miljkovi, Milena Nikodijevi and Du an Trajkovi Milena Nikodijevi and Du an Trajkovi
Disperse dyes are essentially non – ionic, exhibit poor solubility in water, and they can be used in the form of water dispersion. Polyester fibres are resistant to dilute aqueous acids and alkaline solutions and pH value does not provide a crucial impact on the dyeing mechanism; however, many disperse dyes undergo degradation if the pH is uncontrolled during aqueous dyeing. In order to minimize the possibility of dye hydrolysis, the dyeing is carried out in a slightly acidic medium, and pH is usually adjusted with acetic acid. In this work, the quantity of disperse dyes (Sinten Gelb P-5GL and Sinten Scharlach P-3GL) applied to polyester knitwear was investigated as a function of pH. The sorption capacity of polyester knitwear was monitored by using reflection curves and CIELab system, according to Swiss software Sandoz (based on spectrophotometry). The acetic acid was used for dyebath pH adjustment. The results showed that the maximum uptake of Sinten Gelb P-5GL and SintenScharlach P-3GL dyes by polyester knitwear occurred at pH 4.64 (0.2924%) and 6.20 (0.1860%), respectively. According to reflection curves in the range (max = 400-700 nm), the effect of pH on the sorption of Sinten Gelb P-5GL was more significant than one for Sinten Scharlach P-3GL, when concentration of dye is constant (0.4%). The CIELab values for three illuminants (daylight, light – bulb and incandescent) showed a significant dependence between pH float and hue and intensity of polyester knitwear dyeing with disperse dyes
{"title":"The Influence of pH of Float on the Dyeability of Polyester Fabric","authors":"Milena Miljkovi Milena Miljkovi, Sandra S Konstantinovi Sandra S Konstantinovi, Vojkan M Miljkovi Vojkan M Miljkovi, Milena Nikodijevi and Du an Trajkovi Milena Nikodijevi and Du an Trajkovi","doi":"10.52568/001241/jcsp/45.03.2023","DOIUrl":"https://doi.org/10.52568/001241/jcsp/45.03.2023","url":null,"abstract":"Disperse dyes are essentially non – ionic, exhibit poor solubility in water, and they can be used in the form of water dispersion. Polyester fibres are resistant to dilute aqueous acids and alkaline solutions and pH value does not provide a crucial impact on the dyeing mechanism; however, many disperse dyes undergo degradation if the pH is uncontrolled during aqueous dyeing. In order to minimize the possibility of dye hydrolysis, the dyeing is carried out in a slightly acidic medium, and pH is usually adjusted with acetic acid. In this work, the quantity of disperse dyes (Sinten Gelb P-5GL and Sinten Scharlach P-3GL) applied to polyester knitwear was investigated as a function of pH. The sorption capacity of polyester knitwear was monitored by using reflection curves and CIELab system, according to Swiss software Sandoz (based on spectrophotometry). The acetic acid was used for dyebath pH adjustment. The results showed that the maximum uptake of Sinten Gelb P-5GL and SintenScharlach P-3GL dyes by polyester knitwear occurred at pH 4.64 (0.2924%) and 6.20 (0.1860%), respectively. According to reflection curves in the range (max = 400-700 nm), the effect of pH on the sorption of Sinten Gelb P-5GL was more significant than one for Sinten Scharlach P-3GL, when concentration of dye is constant (0.4%). The CIELab values for three illuminants (daylight, light – bulb and incandescent) showed a significant dependence between pH float and hue and intensity of polyester knitwear dyeing with disperse dyes","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70708644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.52568/001282/jcsp/45.04.2023
Fatima Javed Fatima Javed, Saqib Ali Saqib Ali, Khurram Shahzad Munawar Khurram Shahzad Munawar, Ali Haider Ali Haider, N. A. S. A. Z. R. N A Shah and Z Rashid
Exploring the therapeutic potential of organotin-based oxo-ethyl carbonodithioates, a series of organotin(IV) thiocarboamates (1-5) were synthesized with diverse alkyl and phenyl substituents. The chemical- composition, morphology, theoretical properties, and drug-DNA binding capabilities of the synthesized derivatives were performed by applying different characterization techniques like FT-IR, NMR (1H, 13C), AFM, DFT analysis, and UV-Vis spectroscopy respectively. The NMR data indicated six and four coordinated geometries, while the AFM results revealed smart surfaces concerning the grain size and root mean square (RMS) roughness, signifying catalytic and biocidal uses. The drug-DNA binding via intercalative mode of interaction with blue and red shifts was determined by using using UV spectroscopy. The in vitro biocidal capacity of selected complexes was evaluated against typical bacterial, fungal, cytotoxic, and leishmanial strains respectively. As a result of the surface and biocidal characterization, the synthesized complexes may be applied with greater potential in biomedical, pharmaceutical, infectious, catalysis, and cosmetics industries
{"title":"Synthesis, Structural Elucidation, and Therapeutic Screening of Organotin(IV) derivatives of oxo-ethyl carbonodithioate","authors":"Fatima Javed Fatima Javed, Saqib Ali Saqib Ali, Khurram Shahzad Munawar Khurram Shahzad Munawar, Ali Haider Ali Haider, N. A. S. A. Z. R. N A Shah and Z Rashid","doi":"10.52568/001282/jcsp/45.04.2023","DOIUrl":"https://doi.org/10.52568/001282/jcsp/45.04.2023","url":null,"abstract":"Exploring the therapeutic potential of organotin-based oxo-ethyl carbonodithioates, a series of organotin(IV) thiocarboamates (1-5) were synthesized with diverse alkyl and phenyl substituents. The chemical- composition, morphology, theoretical properties, and drug-DNA binding capabilities of the synthesized derivatives were performed by applying different characterization techniques like FT-IR, NMR (1H, 13C), AFM, DFT analysis, and UV-Vis spectroscopy respectively. The NMR data indicated six and four coordinated geometries, while the AFM results revealed smart surfaces concerning the grain size and root mean square (RMS) roughness, signifying catalytic and biocidal uses. The drug-DNA binding via intercalative mode of interaction with blue and red shifts was determined by using using UV spectroscopy. The in vitro biocidal capacity of selected complexes was evaluated against typical bacterial, fungal, cytotoxic, and leishmanial strains respectively. As a result of the surface and biocidal characterization, the synthesized complexes may be applied with greater potential in biomedical, pharmaceutical, infectious, catalysis, and cosmetics industries","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70709054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.52568/001210/jcsp/45.02.2023
Rui Pan Rui Pan, Rumeng Jiang Rumeng Jiang, Yao Chen and Jiancheng Zhou Yao Chen and Jiancheng Zhou
Mass production of Epichlorohydrin (ECH) via epoxidizing allyl chloride suffers from determining the optimal reaction parameters and reproducibility. Titanium silicalite-1 (TS-1) catalyst has been successfully employed to reduce activation energy, but many reaction conditions are involved in the process. To optimize ECH production by analysing its yields, Taguchi method was implemented for reducing time and cost. Included in the reaction parameters were reaction temperature, reaction time and the reactant ratio. This study investigated preparation of heterogeneous catalysts using hydrothermal method and their characterization by XRD, IR, SEM and TEM, which confirmed the presence of ordered MFI structure. Plots of S/N suggested that reaction time was the most influential factor, followed by reaction time in ECH production. The optimum factor parameters were acquired as follows, a reaction time of 40 min, reaction temperature of 90 oC and the molar ratio of H2O2: allyl chloride equal to 1. Aimed at the final confirmation, ECH production experiment was also practiced. Established on the obtained results, the yield of ECH was hugely upgraded to the value of 83.13and#177;1.03 % with only ~0.7% deviated from predicted value.
{"title":"Optimization of the Production of Epichlorohydrin Catalyzed by TS-1 Using the Taguchi Method","authors":"Rui Pan Rui Pan, Rumeng Jiang Rumeng Jiang, Yao Chen and Jiancheng Zhou Yao Chen and Jiancheng Zhou","doi":"10.52568/001210/jcsp/45.02.2023","DOIUrl":"https://doi.org/10.52568/001210/jcsp/45.02.2023","url":null,"abstract":"Mass production of Epichlorohydrin (ECH) via epoxidizing allyl chloride suffers from determining the optimal reaction parameters and reproducibility. Titanium silicalite-1 (TS-1) catalyst has been successfully employed to reduce activation energy, but many reaction conditions are involved in the process. To optimize ECH production by analysing its yields, Taguchi method was implemented for reducing time and cost. Included in the reaction parameters were reaction temperature, reaction time and the reactant ratio. This study investigated preparation of heterogeneous catalysts using hydrothermal method and their characterization by XRD, IR, SEM and TEM, which confirmed the presence of ordered MFI structure. Plots of S/N suggested that reaction time was the most influential factor, followed by reaction time in ECH production. The optimum factor parameters were acquired as follows, a reaction time of 40 min, reaction temperature of 90 oC and the molar ratio of H2O2: allyl chloride equal to 1. Aimed at the final confirmation, ECH production experiment was also practiced. Established on the obtained results, the yield of ECH was hugely upgraded to the value of 83.13and#177;1.03 % with only ~0.7% deviated from predicted value.","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70708268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Textile dyes are hazardous and carcinogenic materials. Hence, their removal from wastewater is globally required. This research aims to remove anionic dye red bemacid E-TL from aqueous solutions using a biofilm supported on granular pozzolana in a fixed-bed column. The effect of different experimental conditions such as influent dye concentrations, flow rate and bed depth on red bemacid biosorption at room temperature were investigated. Results indicated that the breakthrough and saturation time increase with the decrease of the flow rate. The same effect is shown when the bed depth is increased. Favorable conditions for dye removal were observed with 60 cm of column height, lowest flow rate 1mL/min and initial red bemacid concentration of 60 mg/L; at which the highest removal efficiency of 52,68% were recorded. The breakthrough data obtained for RB E-TL removal fitted Thomas and Yoon-Nelson model with high correlation coefficients (R2 = 0,992). The results obtained proved that fixed microorganisms biomass could be a promising biosorbent for the removal of red bemacid from aqueous solutions in a dynamic process.
{"title":"Removal of Textile Dye from Aqueous Solution Using Immobilized Cells on Column pozzolana Bed Reactor","authors":"Cherifi Souad Cherifi Souad, Djafer Abderrahmane Djafer Abderrahmane, Mehdaoui Razika Mehdaoui Razika, Sameut Bouhaik Izzeddine Sameut Bouhaik Izzeddine, Fizir Meriem and Iddou Abdelkader Fizir Meriem and Iddou Abdelkader","doi":"10.52568/001212/jcsp/45.02.2023","DOIUrl":"https://doi.org/10.52568/001212/jcsp/45.02.2023","url":null,"abstract":"Textile dyes are hazardous and carcinogenic materials. Hence, their removal from wastewater is globally required. This research aims to remove anionic dye red bemacid E-TL from aqueous solutions using a biofilm supported on granular pozzolana in a fixed-bed column. The effect of different experimental conditions such as influent dye concentrations, flow rate and bed depth on red bemacid biosorption at room temperature were investigated. Results indicated that the breakthrough and saturation time increase with the decrease of the flow rate. The same effect is shown when the bed depth is increased. Favorable conditions for dye removal were observed with 60 cm of column height, lowest flow rate 1mL/min and initial red bemacid concentration of 60 mg/L; at which the highest removal efficiency of 52,68% were recorded. The breakthrough data obtained for RB E-TL removal fitted Thomas and Yoon-Nelson model with high correlation coefficients (R2 = 0,992). The results obtained proved that fixed microorganisms biomass could be a promising biosorbent for the removal of red bemacid from aqueous solutions in a dynamic process.","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70708352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.52568/001287/jcsp/45.04.2023
Jie Zhang Jie Zhang, Ri Xia Ri Xia, Xianchun Li and Jiasheng Xu Xianchun Li and Jiasheng Xu
The porous cobaltosic oxide (Co3O4) arrays has been prepared by a chemical co-precipitation route using the nickel foam as s substrate. Cyclic voltammetry (CV), and ampere current method (i-t curve) are used to explore the non-enzymatic glucose sensor in a three-electrode system. This porous Co3O4 array non-enzymatic sensor shows a sensitivity of 592.8 mA mM1 cm2 in concentration from 0.99 M to 1.073 mM. The porous Co3O4 array sensor electrode also showed low LOD value (0.005 M) and fast response time (4 s). This porous Co3O4 electrode shows a good sensor performance due to these rich redox reaction sites in the unique porous structure. This porous cobaltosic oxide arrays maybe a potential sensor material in the glucose detection application
以泡沫镍为衬底，采用化学共沉淀法制备了多孔氧化钴(Co3O4)阵列。采用循环伏安法(CV)和安培电流法(i-t曲线)对三电极系统中的非酶葡萄糖传感器进行了研究。该多孔Co3O4阵列非酶传感器在浓度范围为0.99M ~ 1.073 mM范围内的灵敏度为592.8 mA mM (1 cm) mg (1 cm) mg(2)，且具有较低的LOD值(0.005M)和快速的响应时间(4 s)。该多孔Co3O4电极独特的多孔结构中含有丰富的氧化还原反应位点，具有良好的传感器性能。这种多孔氧化钴阵列可能是葡萄糖检测中潜在的传感器材料
{"title":"Fabrication of Porous Co3O4 Arrays by a Co-Precipitation Method and it Application as a Non-Enzymatic Glucose Sensor","authors":"Jie Zhang Jie Zhang, Ri Xia Ri Xia, Xianchun Li and Jiasheng Xu Xianchun Li and Jiasheng Xu","doi":"10.52568/001287/jcsp/45.04.2023","DOIUrl":"https://doi.org/10.52568/001287/jcsp/45.04.2023","url":null,"abstract":"The porous cobaltosic oxide (Co3O4) arrays has been prepared by a chemical co-precipitation route using the nickel foam as s substrate. Cyclic voltammetry (CV), and ampere current method (i-t curve) are used to explore the non-enzymatic glucose sensor in a three-electrode system. This porous Co3O4 array non-enzymatic sensor shows a sensitivity of 592.8 mA mM1 cm2 in concentration from 0.99 M to 1.073 mM. The porous Co3O4 array sensor electrode also showed low LOD value (0.005 M) and fast response time (4 s). This porous Co3O4 electrode shows a good sensor performance due to these rich redox reaction sites in the unique porous structure. This porous cobaltosic oxide arrays maybe a potential sensor material in the glucose detection application","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70709183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.52568/001196/jcsp/45.01.2023
A. R. A Rauf, T. A. T Ahmad, H. A. H Ahmad, I. A. K. I A Khan, S. U. A. S. S U A Shah, A. A Ali, N. M. N Muhammad, Y. S. A. A. O. B. Y S Al Awthan O Bahattab, M. A. A. D. M A Al Duais, M. S. M. M S Mubarak
Syzygium cumini L is an evergreen medicinal plant belonging to the family Myrtaceae, and is one of the important species of the genus Syzygium. S. cumini is traditionally used to treat various infections such as sore throat, bronchitis, dysentery, and other painful conditions. The aim of the current study was to evaluate fixed oil extracted from S. cumini for various in vitro and in vivo biological activities and identification of its fatty acids constituents. GC-MS analysis of the fixed oil revealed that the major constituents are palmitic acid methyl ester (56.45%) and stearic acid methyl ester (29.54%). Fixed oil isolated from S. cumini exhibited significant effect against Staphylococcus aureus, Shigella flexenari, and Bacillus subtilis with zone of inhibition of 28.09, 27.34, and 22.76 mm, respectively. In addition, the oil exhibited antifungal effect against Aspergillus flavus, Candida glabrata, Microsporum canis, and Fusarium solani with zone of inhibition of 80.77, 75.08, 70.98, and 65.56 mm, respectively. The oil also exerted analgesic potential at the dose of 10, 20, 40, and 60 mg/Kg with 35.44, 50.45, 65.98, and 80.34 % activity in acetic acid-induced writhing model. A mild muscle relaxant effect was noted in animal models. Taken all together, the fixed oil from S. cumini exhibits significant antimicrobial, antifungal and analgesic effects, which justifies the use of this plant in folk medicine.
{"title":"Identification and Pharmacological Evaluation of Syzygium cumini Derived Fixed Oils","authors":"A. R. A Rauf, T. A. T Ahmad, H. A. H Ahmad, I. A. K. I A Khan, S. U. A. S. S U A Shah, A. A Ali, N. M. N Muhammad, Y. S. A. A. O. B. Y S Al Awthan O Bahattab, M. A. A. D. M A Al Duais, M. S. M. M S Mubarak","doi":"10.52568/001196/jcsp/45.01.2023","DOIUrl":"https://doi.org/10.52568/001196/jcsp/45.01.2023","url":null,"abstract":"Syzygium cumini L is an evergreen medicinal plant belonging to the family Myrtaceae, and is one of the important species of the genus Syzygium. S. cumini is traditionally used to treat various infections such as sore throat, bronchitis, dysentery, and other painful conditions. The aim of the current study was to evaluate fixed oil extracted from S. cumini for various in vitro and in vivo biological activities and identification of its fatty acids constituents. GC-MS analysis of the fixed oil revealed that the major constituents are palmitic acid methyl ester (56.45%) and stearic acid methyl ester (29.54%). Fixed oil isolated from S. cumini exhibited significant effect against Staphylococcus aureus, Shigella flexenari, and Bacillus subtilis with zone of inhibition of 28.09, 27.34, and 22.76 mm, respectively. In addition, the oil exhibited antifungal effect against Aspergillus flavus, Candida glabrata, Microsporum canis, and Fusarium solani with zone of inhibition of 80.77, 75.08, 70.98, and 65.56 mm, respectively. The oil also exerted analgesic potential at the dose of 10, 20, 40, and 60 mg/Kg with 35.44, 50.45, 65.98, and 80.34 % activity in acetic acid-induced writhing model. A mild muscle relaxant effect was noted in animal models. Taken all together, the fixed oil from S. cumini exhibits significant antimicrobial, antifungal and analgesic effects, which justifies the use of this plant in folk medicine.","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70707672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.52568/001247/jcsp/45.03.2023
Xinyu Zhang Xinyu Zhang, Jiajun Li Jiajun Li, Ming Guo Ming Guo, Kaijie Ni Kaijie Ni, Ronghui Wu and Zhiyan Hu Ronghui Wu and Zhiyan Hu
In this study, a two-dimensional transition metal carbon/nitride (MXenes) method was used to enhance the electrocatalytic oxidation behavior of PbO2 electrode. A novel composite electrode was prepared by doping the modified MXenes into PbO2 material. The electrochemical performance was tested by electrochemical workstation. The typical cationic red X-GRL was treated by electrochemical oxidation, and the electrochemical oxidation performance of the material electrode was investigated. The results demostrated that the dyes were removed by the oxygen evolution reaction at the electrodes doped with modified MXenes by passing current. The charge transfer resistance is 12.56. The electrodes have remained stable after 20 cycles of charging and discharging. And the removal rate of cationic red X-GRL was as high as 95.19% in 120 min. A high-efficiency composite electrode was developed in this study, which increased the electrodeand#39;s performance as well as wastewater degradation efficiency, and lay the groundwork for future research into doping MXenes to improve the performance of other materials. Hence, electrode materials doped with two-dimensional structured MXenes were candidates for the removal of contaminants, especially in the field of electrochemical catalysis
{"title":"Electrocatalytic Oxidation Performance of PbO2 Composite Electrode Doped with MXenes","authors":"Xinyu Zhang Xinyu Zhang, Jiajun Li Jiajun Li, Ming Guo Ming Guo, Kaijie Ni Kaijie Ni, Ronghui Wu and Zhiyan Hu Ronghui Wu and Zhiyan Hu","doi":"10.52568/001247/jcsp/45.03.2023","DOIUrl":"https://doi.org/10.52568/001247/jcsp/45.03.2023","url":null,"abstract":"In this study, a two-dimensional transition metal carbon/nitride (MXenes) method was used to enhance the electrocatalytic oxidation behavior of PbO2 electrode. A novel composite electrode was prepared by doping the modified MXenes into PbO2 material. The electrochemical performance was tested by electrochemical workstation. The typical cationic red X-GRL was treated by electrochemical oxidation, and the electrochemical oxidation performance of the material electrode was investigated. The results demostrated that the dyes were removed by the oxygen evolution reaction at the electrodes doped with modified MXenes by passing current. The charge transfer resistance is 12.56. The electrodes have remained stable after 20 cycles of charging and discharging. And the removal rate of cationic red X-GRL was as high as 95.19% in 120 min. A high-efficiency composite electrode was developed in this study, which increased the electrodeand#39;s performance as well as wastewater degradation efficiency, and lay the groundwork for future research into doping MXenes to improve the performance of other materials. Hence, electrode materials doped with two-dimensional structured MXenes were candidates for the removal of contaminants, especially in the field of electrochemical catalysis","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70708806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.52568/001286/jcsp/45.04.2023
Ali Amer Waheb Ali Amer Waheb, Ashraf Saad Rasheed and Mohammed J M Hassan Ashraf Saad Rasheed and Mohammed J M Hassan
Flurbiprofen and ketorolac are non-steroidal anti-inflammatory drugs (NSAIDs) that include both hydrophilic and hydrophobic functional groups in their structures. By connecting sulfobetaine molecules to polystyrene-divinylbenzene particles, two ZIC-HILIC stationary phases (ZIC-SB1 and ZIC-SB4) were developed for chromatographic separation of NSAIDs with varying chain lengths using Ultraviolet as detection. The different chain lengths of the stationary phases are utilized to investigate the retention behaviour of NSAIDs. Simultaneous quantification methods for ZIC-HILIC were developed. Flurbiprofen and ketorolac exhibited high precision with a small relative standard deviation (RSD) value of 0.48%, linear ranges of 0.015-6 and 0.06-4.5 ppm and detection limits of 0.009-0.006 and 0.01-0.008 ppm with a coefficient of determination (R2) of 0.9995-0.9997 for the ZIC-SB1 and ZIC-SB4 stationary phases, respectively. Statistical testing was used to compare the approaches to the British Pharmacopoeia protocol, and no difference in accuracy was discovered.
{"title":"Study the Effect of Zwitterionic Hydrophilic Interaction for Simultaneous Determination of Non-Steroidal Anti-Inflammatory Drugs in Dosage Forms","authors":"Ali Amer Waheb Ali Amer Waheb, Ashraf Saad Rasheed and Mohammed J M Hassan Ashraf Saad Rasheed and Mohammed J M Hassan","doi":"10.52568/001286/jcsp/45.04.2023","DOIUrl":"https://doi.org/10.52568/001286/jcsp/45.04.2023","url":null,"abstract":"Flurbiprofen and ketorolac are non-steroidal anti-inflammatory drugs (NSAIDs) that include both hydrophilic and hydrophobic functional groups in their structures. By connecting sulfobetaine molecules to polystyrene-divinylbenzene particles, two ZIC-HILIC stationary phases (ZIC-SB1 and ZIC-SB4) were developed for chromatographic separation of NSAIDs with varying chain lengths using Ultraviolet as detection. The different chain lengths of the stationary phases are utilized to investigate the retention behaviour of NSAIDs. Simultaneous quantification methods for ZIC-HILIC were developed. Flurbiprofen and ketorolac exhibited high precision with a small relative standard deviation (RSD) value of 0.48%, linear ranges of 0.015-6 and 0.06-4.5 ppm and detection limits of 0.009-0.006 and 0.01-0.008 ppm with a coefficient of determination (R2) of 0.9995-0.9997 for the ZIC-SB1 and ZIC-SB4 stationary phases, respectively. Statistical testing was used to compare the approaches to the British Pharmacopoeia protocol, and no difference in accuracy was discovered.","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70709075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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