Joseph M. Lambert, Maria A. Osina, Johanna L. Staubitz, Derek D. Reed, Gregory J. Madden
Progressive ratio analysis (PRA) has been used to quantify the relative reinforcer efficacy of various programmed consequences across basic and applied research paradigms. It has also been used as an alternative methodology for demand-curve analysis. In this study, we enrolled 96 consenting adults with disabilities to participate in a translational controlled consecutive case series. Specifically, we compensated participants for using an arbitrary response (e.g., a die roll) to demonstrate the circumstances under which they would work to earn preferred reinforcers in both Basis x PRA and progressive fixed ratio analysis (PFRA) paradigms. Using t tests of logarithmically transformed Pearson correlation coefficients, we established that Basis x PRA did not correlate with metrics of demand elasticity obtained from PFRA. However, Basis x PRA significantly predicted multiple metrics of equilibrium observed during PFRA. Consequently, the assessment likely retains prescriptive value across a number of domains.
递进比率分析(PRA)已被用于量化各种程序化结果在基础和应用研究范式中的相对强化效应。它也被用作需求曲线分析的另一种方法。在这项研究中,我们招募了96名同意的成年残疾患者参加一个翻译对照连续病例系列。具体来说,我们补偿了参与者使用任意反应(例如,掷骰子)来展示他们将在Basis x PRA和渐进式固定比率分析(PFRA)范式中努力获得首选强化的情况。使用对数变换的Pearson相关系数的t检验,我们确定Basis x PRA与从PFRA获得的需求弹性指标不相关。然而,Basis x PRA显著预测了PFRA期间观察到的多个平衡指标。因此,评估可能在许多领域中保留规定性价值。
{"title":"Evaluating contributions of progressive ratio analysis to economic metrics of demand","authors":"Joseph M. Lambert, Maria A. Osina, Johanna L. Staubitz, Derek D. Reed, Gregory J. Madden","doi":"10.1002/jeab.70077","DOIUrl":"10.1002/jeab.70077","url":null,"abstract":"<p>Progressive ratio analysis (PRA) has been used to quantify the relative reinforcer efficacy of various programmed consequences across basic and applied research paradigms. It has also been used as an alternative methodology for demand-curve analysis. In this study, we enrolled 96 consenting adults with disabilities to participate in a translational controlled consecutive case series. Specifically, we compensated participants for using an arbitrary response (e.g., a die roll) to demonstrate the circumstances under which they would work to earn preferred reinforcers in both Basis <i>x</i> PRA and progressive fixed ratio analysis (PFRA) paradigms. Using <i>t</i> tests of logarithmically transformed Pearson correlation coefficients, we established that Basis <i>x</i> PRA did not correlate with metrics of demand elasticity obtained from PFRA. However, Basis <i>x</i> PRA significantly predicted multiple metrics of equilibrium observed during PFRA. Consequently, the assessment likely retains prescriptive value across a number of domains.</p>","PeriodicalId":17411,"journal":{"name":"Journal of the experimental analysis of behavior","volume":"125 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12742636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Although differential reinforcement of alternative behavior (DRA) is frequently successful in decreasing challenging behavior, relapse of previously reduced behavior can occur. Renewal is a form of relapse following a context change. This human-operant experiment evaluated a context-fading procedure to mitigate renewal during DRA with asymmetrical reinforcers for two alternative responses (i.e., differing magnitudes of points). Thirty-six participants were assigned to a context-fading or control group. During the first phase, the target response was reinforced in Context A. During the second phase, the target response was on extinction and two alternative responses were reinforced in Context B. For the context-fading group, the background color shifted from Context B to Context A. For the no-fading group, Phase 2 occurred entirely in Context B. Context A was reintroduced during the renewal test, with reinforcement contingencies identical to those in Phase 2. Renewal occurred for 17 of 18 participants (94.44%) without fading and only nine of 18 (50.00%) with fading. The magnitude of renewal was also greater for the no-fading group. These findings suggest context fading may be an effective strategy to mitigate renewal, although it may also produce temporary increases in the target response during the fading process.
{"title":"Reducing renewal with context fading during differential reinforcement procedures","authors":"Kacey R. Finch Jackson, Kathryn M. Kestner","doi":"10.1002/jeab.70078","DOIUrl":"10.1002/jeab.70078","url":null,"abstract":"<p>Although differential reinforcement of alternative behavior (DRA) is frequently successful in decreasing challenging behavior, relapse of previously reduced behavior can occur. Renewal is a form of relapse following a context change. This human-operant experiment evaluated a context-fading procedure to mitigate renewal during DRA with asymmetrical reinforcers for two alternative responses (i.e., differing magnitudes of points). Thirty-six participants were assigned to a context-fading or control group. During the first phase, the target response was reinforced in Context A. During the second phase, the target response was on extinction and two alternative responses were reinforced in Context B. For the context-fading group, the background color shifted from Context B to Context A. For the no-fading group, Phase 2 occurred entirely in Context B. Context A was reintroduced during the renewal test, with reinforcement contingencies identical to those in Phase 2. Renewal occurred for 17 of 18 participants (94.44%) without fading and only nine of 18 (50.00%) with fading. The magnitude of renewal was also greater for the no-fading group. These findings suggest context fading may be an effective strategy to mitigate renewal, although it may also produce temporary increases in the target response during the fading process.</p>","PeriodicalId":17411,"journal":{"name":"Journal of the experimental analysis of behavior","volume":"125 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145819800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Schedule-induced polydipsia (SIP) arises when subjects consume excessive amounts of water during interval responding on operant tasks, a paradigm introduced and mostly developed in rats. Neuropharmacological studies conducted on SIP have mainly shown a prominent role of dopamine and 5HT in this adjunctive behavior. In particular, D1/D2 receptor antagonists decrease SIP, whereas low doses of dopamine reuptake blockers increase SIP. There is more specific evidence of a decline in SIP after lesions of the mesolimbic dopamine pathway. A decline in SIP is likewise observed after the injection of 5HT reuptake blockers and modulated by 5HT2A/5HT2C receptor agonists and antagonists. Despite more limited studies with other neurotransmitter systems, SIP has so far been shown to decline after the injection of muscarinic or NMDA receptor antagonists as well as benzodiazepine receptor agonists. Under some conditions, the role of neuroendocrine factors is shown by alterations in blood corticosterone levels during the course of SIP, indicative of its stress-reducing properties.
{"title":"A review of the neuropharmacological profile of schedule-induced polydipsia","authors":"Robert Lalonde, Catherine Strazielle","doi":"10.1002/jeab.70069","DOIUrl":"10.1002/jeab.70069","url":null,"abstract":"<p>Schedule-induced polydipsia (SIP) arises when subjects consume excessive amounts of water during interval responding on operant tasks, a paradigm introduced and mostly developed in rats. Neuropharmacological studies conducted on SIP have mainly shown a prominent role of dopamine and 5HT in this adjunctive behavior. In particular, D<sub>1</sub>/D<sub>2</sub> receptor antagonists decrease SIP, whereas low doses of dopamine reuptake blockers increase SIP. There is more specific evidence of a decline in SIP after lesions of the mesolimbic dopamine pathway. A decline in SIP is likewise observed after the injection of 5HT reuptake blockers and modulated by 5HT<sub>2A</sub>/5HT<sub>2C</sub> receptor agonists and antagonists. Despite more limited studies with other neurotransmitter systems, SIP has so far been shown to decline after the injection of muscarinic or NMDA receptor antagonists as well as benzodiazepine receptor agonists. Under some conditions, the role of neuroendocrine factors is shown by alterations in blood corticosterone levels during the course of SIP, indicative of its stress-reducing properties.</p>","PeriodicalId":17411,"journal":{"name":"Journal of the experimental analysis of behavior","volume":"125 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Beatriz E. Arroyo Antúnez, Sean W. Smith, Charlene N. Agnew, Kate E. Derrenbacker, William E. Sullivan, Henry S. Roane, Andrew R. Craig
Alternative-reinforcement-based treatments are common strategies for reducing maladaptive behavior in humans. When conditions of alternative reinforcement are made worse in some way, however, behavior that was targeted for elimination may resurge. Previous research using rat subjects has demonstrated that high-magnitude (relative to low-magnitude) alternative reinforcement produces faster elimination of target behavior but more resurgence once removed. The purpose of the present experiment was to assess cross-species generality of these effects to mice. During Phase 1, lever pressing produced single food pellet reinforcers. Next, during Phase 2, lever pressing was extinguished and groups of mice experienced either small-magnitude (one pellet), large-magnitude (three pellet), or no alternative reinforcement for nose poking. All food was suspended in Phase 3 to assess resurgence. As an additional goal of this study, changes in resurgence across successive determinations were assessed by cycling between periods during which alternative reinforcement was present or absent. Large-magnitude alternative reinforcers produced faster suppression of target behavior but more resurgence when removed than did small-magnitude alternative reinforcers. Moreover, this effect endured across repeated resurgence tests.
{"title":"Alternative-reinforcer magnitude effects on resurgence across successive relapse tests in mice","authors":"Beatriz E. Arroyo Antúnez, Sean W. Smith, Charlene N. Agnew, Kate E. Derrenbacker, William E. Sullivan, Henry S. Roane, Andrew R. Craig","doi":"10.1002/jeab.70070","DOIUrl":"10.1002/jeab.70070","url":null,"abstract":"<p>Alternative-reinforcement-based treatments are common strategies for reducing maladaptive behavior in humans. When conditions of alternative reinforcement are made worse in some way, however, behavior that was targeted for elimination may resurge. Previous research using rat subjects has demonstrated that high-magnitude (relative to low-magnitude) alternative reinforcement produces faster elimination of target behavior but more resurgence once removed. The purpose of the present experiment was to assess cross-species generality of these effects to mice. During Phase 1, lever pressing produced single food pellet reinforcers. Next, during Phase 2, lever pressing was extinguished and groups of mice experienced either small-magnitude (one pellet), large-magnitude (three pellet), or no alternative reinforcement for nose poking. All food was suspended in Phase 3 to assess resurgence. As an additional goal of this study, changes in resurgence across successive determinations were assessed by cycling between periods during which alternative reinforcement was present or absent. Large-magnitude alternative reinforcers produced faster suppression of target behavior but more resurgence when removed than did small-magnitude alternative reinforcers. Moreover, this effect endured across repeated resurgence tests.</p>","PeriodicalId":17411,"journal":{"name":"Journal of the experimental analysis of behavior","volume":"125 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145724094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}