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PENGARUH PENAMBAHAN ASAM SITRAT PADA EKSTRAKSI DAUN JATI (Tectona grandis Linn.f.) TERHADAP SIFAT FISIK SEDIAAN SHEER LIPSTICK 加入柚木叶酸的影响(Tectona grandis Linn.f.)来抑制唇膏的生理倾向
Pub Date : 2022-12-20 DOI: 10.53864/jifakfar.v2i2.135
Mikhania C.E., Kukuh Judy Handojo, Lailatul Fitriyah
The aim of this study was to know the influence of citric acid addition on teak leaf (Tectona grandis Linn.f.) extraction to the physical properties of sheer lipstick. Physical properties of sheer lipstick include organoleptic test and pH test. The result data for organoleptic test of sheer lipstick color using teak leaves extracted with 3% citric acid addition (F1) was yielded pink, 5% (F2) was red and 7% (F3) was dark red. The organoleptic test of the aroma from three formulas has the same particular odor of essence strawberry. Data of pH test result from three formulations of sheer lipstick using teak leaves extracted with 3% citric acid (F1) was 3,867 ± 0,115, 5% (F2) was 3,467 ± 0,208 and 7% (F3) was 3,233 ±0,057. Data analysis of pH using One Way Anova obtained significance value 0,004 (p <0,05) therefore can be interpreted that there was significant difference of pH from all formulation. From the results it can be concluded that the preparation sheer lipstick using teak leaf extract with addition of citric acid 3%, 5% and 7% influence physical properties of color and pH, but didn’t influence odor.
本研究的目的是了解柚木叶(Tectona grandis Linn.f.)提取过程中柠檬酸的添加对纯唇膏物理性能的影响。纯唇膏的物理性能包括感官测试和pH值测试。添加3%柠檬酸提取的柚木叶(F1)对纯口红颜色进行感官测试的结果为粉红色,5% (F2)为红色,7% (F3)为暗红色。三种配方的香气感官测试均具有相同的草莓香精特有气味。用3%柠檬酸提取柚木叶(F1)配制的三种纯唇膏pH值分别为3,867±0,115、5% (F2)为3,467±0,208、7% (F3)为3,233±0,057。用单因素方差分析pH值得到显著性值0.004 (p < 0.05),因此可以解释各制剂的pH值存在显著性差异。结果表明,柚叶提取物在柠檬酸添加量为3%、5%和7%的情况下制备纯口红,对颜色和pH值的物理性质有影响,但对气味没有影响。
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引用次数: 0
HUBUNGAN TINGKAT PENGETAHUAN DENGAN TINDAKAN PENCEGAHAN KANKER SERVIKS PASCA PENYULUHAN PADA WANITA USIA SUBUR 知识水平与接受育龄妇女宫颈癌治疗措施的关系
Pub Date : 2022-12-20 DOI: 10.53864/jifakfar.v2i2.134
Farida Anwari, Acivrida Mega Charisma
Cervical cancer is the number one cause of death in Indonesian women. Cervical cancer is a malignant tumor that grows inside the cervix / cervix is the lowest part of the uterus that attaches to the top of the vagina. The high number of cases is due to limited access to screening, treatment and lack of information and services to the disease. This cervical cancer can be detected early by doing pap smaer examination.This study aims to determine the relationship between the knowledge level of cervical cancer and its prevention measures in women of childbearing age in Kabupatn Gresik East Java.Design The research used is descriptive, data collection using questionnaires given to women participants counseling in Gresik district of East Java with the total population of 68 respondents and the number of samples were 53 respondents, the selection of respondents based on age is fertile age (15-46 years), married and sexually active.The result of this research by using chi square test showed that there was no significant correlation between age with cervical cancer prevention at post counseling (ρ = 0.187> α = 0.05), there was a significant correlation between level of knowledge with precancement of cervical cancer at post counseling (ρ = 0.025 <α = 0.05).It is hoped that this research can be a reference for health workers in counseling about cervical cancer in women of childbearing age throughout Indonesia, and suggest that people can increase their knowledge about servical cancer and can take precautions by avoiding the risk factors of cervical cancer.
宫颈癌是印尼妇女的头号死因。子宫颈癌是一种生长在子宫颈内的恶性肿瘤/子宫颈是子宫的最低部分,与阴道顶部相连。病例数高是由于获得筛查和治疗的机会有限以及缺乏有关该疾病的信息和服务。这种子宫颈癌可通过巴氏涂片检查及早发现。本研究旨在确定东爪哇Kabupatn Gresik育龄妇女宫颈癌知识水平与预防措施之间的关系。设计本研究采用描述性,资料收集采用问卷方式向东爪哇Gresik区妇女参与者提供咨询,调查对象总数为68人,样本数为53人,调查对象的选择依据年龄是育龄(15-46岁)、已婚和性活跃。卡方检验结果显示,年龄与咨询后宫颈癌预防无显著相关(ρ = 0.187> α = 0.05),知识水平与咨询后宫颈癌前兆有显著相关(ρ = 0.025 <α = 0.05)。希望本研究可以为印尼各地育龄妇女宫颈癌咨询工作提供参考,并建议人们提高对宫颈癌的认识,避免宫颈癌的危险因素,采取预防措施。
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引用次数: 1
POTENSI EKSTRAK ETANOL KULIT BUAH PISANG (Musa acuminata Colla) SEBAGAI OBAT LUKA BAKAR TERHADAP TIKUS GALUR WISTAR PENDERITA DIABETES 香蕉果乙醇的潜在提取物(摩西acuminata Colla)作为治疗糖尿病患者ga抱歉树懒的燃料
Pub Date : 2022-12-20 DOI: 10.53864/jifakfar.v1i2.123
Rosida Hari, Sri Winarsih, Diyan Ajeng R.
Kulit buah pisang merupakan salah satu bahan alami yang dapat digunakan dalam proses penyembuhan luka bakar. Hal ini disebabkan adanya kandungan flavonoid yang memiliki aktivitas antioksidan sehingga dapat mempercepat fase inflamasi dan meningkatkan sintesis kolagen. Tujuan dari penelitian ini membuktikan ekstrak etanol kulit buah pisang (Musa acuminata Colla) dalam proses penyembuhan luka bakar pada tikus galur wistar penderita diabetes. Metode penelitian menggunakan desain pre and post control group. Sebanyak enam belas ekor tikus dibagi menjadi 4 kelompok perlakuan. Kelompok I (kontrol negatif) diberi basis, kelompok II, III dan IV (kelompok perlakuan) diberi ekstrak etanol kulit buah pisang dengan dosis 25%, 50% dan 75%. Sebelum dibuat model luka bakar, tikus diinduksi aloksan dengan dosis 150 mg/kg BB selama tiga hari. Tikus yang digunakan sebagai model luka bakar adalah tikus dengan kadar gula darah diatas 200 mg/dL. Model luas luka bakar sebesar 225 mm2. Pemberian ekstrak kulit buah pisang secara topikal dilakukan tiap hari selama 16 hari. Pengukuran luas luka diamati pada hari ke 4, 8, 12 dan 16. Hasil penelitian menunjukkan bahwa ekstrak kulit buah pisang (Musa acuminata Colla) berpotensi sebagai obat luka bakar pada tikus putih penderita diabetes (p >0,05).
香蕉果皮是一种天然的可用于治疗烧伤的材料。这是由于类黄酮含有抗氧化剂活性,从而加速炎症阶段和增加胶原蛋白合成。这项研究的目的是证明糖尿病患者胃耗子的香蕉果乙醇提取物(摩西acuminata Colla)。研究方法采用预测和后控制组的设计。多达16只老鼠被分为4种治疗类。一组(负控制)被给予基础,二组、三组和四组(治疗小组)接受香蕉果乙醇提取物,剂量为25%、50%和75%。在制作烧伤模型之前,老鼠的剂量为150毫克/kg BB,为期三天。被用作烧伤模型的老鼠是血糖高于200毫克/dL的老鼠。225 mm2的面积烧伤模型。每天局部香蕉皮提取物是16天。在第4天、8天、12天和16天观察伤口的深度测量。研究表明,香蕉果皮提取物(摩西acuminata Colla)对糖尿病白老鼠的灼伤有潜在的疗效(p > 0.05)。
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引用次数: 0
PENGARUH VARIASI KONSENTRASI MINYAK ZAITUN (OLIVE OIL) TERHADAP KELEMBUTAN SABUN CAIR 橄榄油油浓度的变化对液体肥皂的温和影响
Pub Date : 2022-12-20 DOI: 10.53864/jifakfar.v1i2.124
Mikhania Christiningtyas Eryani, Dewi Rashati
Zaitun tree (Olea europaea) comes from the Middle East and widely grown in Asia. The fruit and oil extraction widely used as food and medicine. The oil derived from olives is known as olive oil. Olive oil can be used for skin emolient. The aims of this study was to determine olive oil variation concentration to liquid soap softness. The soap was made with varying olive oil concentration (20% known as F1, 30% known as F2 and 40% known as F3). True experimental design with The Posttest Only Experiment was used as the study design. Evaluation of the soap including organoleptic test, pH, spesific gravity, free alkali assay, and responden emolient test. Responden emolient test was taken from 20 responden who has given questioner. The data from emolient test study was calculate by Kruskal Wallis test. The organoleptic test result showed that all formula showed liquid green, homogen, and jasmine odor. pH from F1, F2 and F3 were 10,39; 9,75 dan 9,34 respectively. The spesicic gravity from F1, F2 and F3 were 1,648%; 1,441% dan 0,863 % respectively. The free alkali from F1, F2 and F3 were 0,032%; 0,08% dan 0,064% respectively. The responden emolient test showed that F1 was soft, F2 was midle soft and F3 was very soft.
载屯树(Olea europaea)原产于中东,在亚洲广泛种植。其果实和榨油广泛用作食品和医药。从橄榄中提取的油被称为橄榄油。橄榄油可用作皮肤润肤剂。本研究的目的是确定橄榄油浓度对液体肥皂柔软度的影响。肥皂是用不同浓度的橄榄油制成的(20%称为F1, 30%称为F2, 40%称为F3)。采用单纯后测实验的真实实验设计作为研究设计。肥皂的评价包括感官试验、pH值、比重、游离碱试验和反应性润肤试验。被调查者的情绪测试是在20名被调查者中进行的。情绪性试验研究数据采用Kruskal - Wallis检验计算。感官测试结果表明,所有配方均呈现液绿、均一、茉莉气味。F1、F2和F3的pH分别为10、39;9、75、9、34。F1、F2和F3的比重为1648%;分别为141%和0.863%。F1、F2和F3的游离碱含量为0.032%;分别为0.08%和0.064%。响应性测试结果显示,F1为软,F2为中软,F3为极软。
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引用次数: 0
PENGARUH VARIASI KONSENTRASI HPMC SEBAGAI GELLING AGENT TERHADAP SIFAT FISIK GEL ANTINYAMUK DAUN KENIKIR (Tagetes erecta L.) HPMC作为一种凝胶剂的浓度变异对坚氏叶藻的物理性质的影响。
Pub Date : 2022-12-20 DOI: 10.53864/jifakfar.v3i2.149
Mikhania C.E., Asa Falahi, D. R. Sari
The aim of this research was to understand the influence of HPMC variation concentration to the physical characteristic anti mosquito gel of extract kenikir leaves (Tagetes erecta L.). Pre-experiment the one shot case study was used as the research design. The variation of HPMC concentration were 2%; 2,5% and 3%. The materials used in this research were kenikir leaves extract, propylenglycol, methyl paraben, jasmine oil and aquadest. The result show that the variation concentration of HPMC give influence to physical properties of organoleptic gel (form, colour), pH and viscosity. The variation concentration of HPMC did not influence homogeneity, spreadibility and smell of the gel.
本研究的目的是了解HPMC变异浓度对万金菊叶提取物抗蚊凝胶物理特性的影响。实验前采用单次个案研究作为研究设计。HPMC浓度变化幅度为2%;2.5%和3%。本研究的主要原料为金盏花叶提取物、丙二醇、对羟基苯甲酸甲酯、茉莉油和水清酯。结果表明,HPMC浓度的变化会影响感官凝胶的物理性质(形态、颜色)、pH值和粘度。HPMC浓度的变化对凝胶的均匀性、铺展性和气味没有影响。
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引用次数: 0
ANALISIS POLIFENOL EKSTRAK TEH TUBRUK KEMASAN MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS
Pub Date : 2022-12-20 DOI: 10.53864/jifakfar.v1i2.126
Hadi Barru Hakam Fajar Siddiq, Rizka Della Yunita Dewi, Jati Riyuwani
The purpose of this research is determine the polyphenol content of brewed tea. Sample were used three sample. Polyphenol compounds of packaged tea were extracted using percolation method with ethanol 70%. Qualitative test were used using FeCl3 reagent and quantitative test polyphenol content were determined using UV-Vis spectrophotometry method with Folin Ciocalteau reagent. Galic acid was used as comparator in this research. The result of qualitative test is all sample of packaged tea containing polyphenol. Polyphenol content sample A, B, and C, with peercolation method were respectively 0,538; 0,554; and 0,470; %b/b.
本研究的目的是测定泡茶中多酚的含量。样本分别采用三个样本。采用70%乙醇浸出法提取包装茶中的多酚类化合物。定性试验采用FeCl3试剂,定量试验采用福林试剂紫外-可见分光光度法测定多酚含量。本研究以没食子酸为比较剂。定性检测结果均为含多酚包装茶样品。样品A、B、C的多酚含量分别为0.538;0554;和0470年;% b / b。
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引用次数: 0
SINTESIS DAN UJI AKTIVITAS ANTIBAKTERI SENYAWA TURUNAN AMOKSISILIN TERHADAP Escherichia coli 阿莫西林菌株和大肠杆菌的抗菌活性的合成和测试
Pub Date : 2022-12-20 DOI: 10.53864/jifakfar.v3i2.151
Hadi Barru Hakam Fajar Siddiq, Siti Nur Azizah, Amaliyah Nurul Hidayah, Dewi Riskha Nurmalasari, Maulika Ria Ekawati, Filia Anggraeni Pradana Putri
Amoxicillin derivate compounds from the reaction of amoxicillin with p-aminophenol are synthesized compounds by reacting amoxicillin and p-aminophenol. . Escherichia coli is a flora normal bacteria that can causing infectious diseases. This research aimed to determine the antibiotic activity of amoxicillin derivat compound (amoxicillin with p-aminophenol) on the growth of E. coli. This research was conducted using the disc diffusion method. amoxicillin derivat compound (amoxicillin with p-aminophenol) were characterized by organoleptic test, melting point determination, pH test determination, Rf value, and maximum wavelength. The results of the organoleptic test showed that amoxicillin derivates from amoxicillin and p-aminophenol reaction is crystal powder, dark brown and bit bitter. Melting point of amoxicillin derivates from amoxicillin and p-aminophenol reaction was 160ºC. pH test of amoxicillin derivates from amoxicillin and p-aminophenol reaction was 6,5. Rf value of amoxicillin derivates from amoxicillin and p-aminophenol reaction was 0,79. The results of UV wavelength scanning showed that amoxicillin derivates from amoxicillin and p-aminophenol reaction at 295 nm. Antibiotic activity showed by the clear zone form around the paper disk. The results showed that E. coli was resistant to pure amoxicillin. Amoxicillin derivat compound (amoxicillin with p-aminophenol) with concentrations of 100% and 12,5% have the largest inhibitory zones (6,33 mm) compared with concentrations of 50% and 25%, 5,33 and 6,00 mm respectively. Based on these results it can be concluded that derivat compound of amoxicillin (amoxicillin with p-aminophenol) has antibiotic activity against the growth of E. coli that has been resistant to pure amoxicillin.
阿莫西林衍生物是由阿莫西林与对氨基酚反应而合成的化合物。大肠杆菌是一种能引起传染病的正常菌群。本研究旨在测定阿莫西林衍生物化合物(阿莫西林-对氨基酚)对大肠杆菌生长的抑菌活性。本研究采用圆盘扩散法进行。采用感官试验、熔点测定、pH值测定、Rf值测定、最大波长测定等方法对阿莫西林衍生物(阿莫西林-对氨基酚)进行表征。感官试验结果表明,阿莫西林与对氨基酚反应生成的阿莫西林衍生物为结晶粉末,深褐色,微苦。阿莫西林衍生物与对氨基酚反应的熔点为160℃。阿莫西林与对氨基酚反应得到的阿莫西林衍生物的pH值分别为6、5。阿莫西林与对氨基酚反应生成的阿莫西林衍生物的Rf值为0.79。紫外波长扫描结果表明,在295 nm处阿莫西林与对氨基酚反应生成阿莫西林衍生物。纸盘周围的透明带显示出抗生素活性。结果表明,大肠杆菌对纯阿莫西林耐药。浓度为100%和12.5%的阿莫西林衍生物(阿莫西林与对氨基酚)与浓度分别为50%和25%、5,33和6,000 mm的阿莫西林衍生物相比,具有最大的抑制区(6,33 mm)。根据这些结果可以得出结论,阿莫西林衍生物化合物(阿莫西林与对氨基酚)对大肠杆菌的生长具有抗生素活性,而大肠杆菌对阿莫西林已产生耐药性。
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引用次数: 0
PENGARUH VARIASI KONSENTRASI HPMC SEBAGAI GELLING AGENT TERHADAP SIFAT FISIK GEL ANTIJAMUR EKSTRAK LENGKUAS (Alpinia galanga (L.) Swartz) 将hpmcc作为GELLING AGENT的浓度变化的影响影响到leng画笔提取物(Alpinia gaan, L)的生理特征。schwartz)
Pub Date : 2022-12-20 DOI: 10.53864/jifakfar.v3i1.154
Mikhania C.E., A. P. Aditama, Sri Agita Ningrum
The aim of this research was to know the influence of HPMC variation concentration as gelling agent againts physical properties antifungal extract galangal gel (Alpinia galanga (L) Swartz). Pre-experimental the one shot case study was used as the research design. Gel is formulated into three formulas with various concentration of HPMC 2% (F1), 3% (F2), and 4% (F3). The materials used in this research were galangal extract, propylenglycol, glycerin, methyl paraben, and aquadest. The result showed that the variation concentration of HPMC give influence to physical properties of organoleptic gel (form, smell and colour), viscosity, and spreadibility of gel but did not influence homogeneity and pH of the gel.
本研究的目的是了解HPMC变化浓度作为胶凝剂对抗真菌提取物高良姜凝胶(Alpinia galanga (L) Swartz)物理性能的影响。实验前采用单次个案研究作为研究设计。将凝胶配制成三种不同浓度的HPMC,分别为2% (F1)、3% (F2)和4% (F3)。本研究采用高良姜提取物、丙二醇、甘油、对羟基苯甲酸甲酯和aquadest。结果表明,HPMC浓度的变化对感官凝胶的物理性质(形态、气味和颜色)、粘度和涂覆性有影响,但对凝胶的均匀性和pH值没有影响。
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引用次数: 0
EVALUASI PENGELOLAAN OBAT PADA EMERGENCY KIT DI RUANGAN RAWAT INAP PADA RUMAH SAKIT BINA SEHAT JEMBER 碧娜健康医院医务室急救包的药物管理评估
Pub Date : 2022-12-20 DOI: 10.53864/jifakfar.v3i2.153
Kukuh Judy Handojo, Vieca Fauziah, Dewi Rashati
Emergency kit management is an important thing to get pay attention because it might be prompt the sentinel event and undesirable effect. Emergency preparations are the medicines that categorized as life saving or life threatening medicines including the medical devices that support emergency condition. The purpose of this study was to determine the percentage of medicine management of emergency kit. The type of research used is descriptive qualitative research and cross sectional (point time approach). The research was conducted in June 2018 at Bina Sehat Hospital Jember. Population and sample in this research is all the medicine management of emergency kit which exist in inpatient room of Bina Sehat Hospital Jember. The sampling technique used is total sampling technique, where all the population used as sample. Research tool of data collection used in this research is using check list. The result of medicine management of emergency kit percentage in inpatient room of Bina Sehat Hospitel Jember regarding the storage management of medicines in emergency kit as much as 59% according to SOP. Distribution of medicines in emergency kit as much as 86,7% according to service guidelines. Replacement medicines that has been used as much as 83% according to SOP. Replacement medicines that damaged or expired as much as 66,6% according to SOP. Monitoring of medicines in emergency kit as much as 84% according to SOP.
应急包的管理是一个重要的事情,要得到重视,因为它可能提示哨事件和不良影响。应急准备是指被归类为挽救生命或威胁生命的药品,包括支持紧急情况的医疗器械。本研究的目的是确定急救箱药物管理的百分比。使用的研究类型是描述性定性研究和横断面(点时间方法)。这项研究于2018年6月在比纳塞哈特医院进行。本研究的人群和样本是比纳塞哈特医院11月住院病房中存在的所有急救箱的药物管理。所采用的抽样技术是总抽样技术,即全部人口作为样本。本研究使用的数据收集研究工具是检查表法。比纳塞哈特医院11月住院室急救箱药品管理结果中,按SOP对急救箱药品存放管理的比例高达59%。根据服务指南,在急救箱中分发药品的比例高达86.7%。根据SOP,已使用的替代药物高达83%。根据SOP,损坏或过期的替代药品高达66.6%。根据SOP对急救箱中的药品进行高达84%的监控。
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引用次数: 1
PENENTUAN KADAR POLIFENOL EKSTRAK TEH KEMASAN DENGAN METODE REMASERASI MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS 用UV-VIS光谱仪测定包装茶叶提取物的多酚含量
Pub Date : 2022-12-20 DOI: 10.53864/jifakfar.v2i1.143
Hadi Barru Hakam Fajar Siddiq, Jati Riyuwani, Rizka Della Yunita Dewi
The purpose of this research is determine the polyphenol content of various brand of packaged tea. Sample were used five sample. Polyphenol compounds of packaged tea were extracted using remaseration method with ethanol 70%. Qualitative test were used using FeCl3 reagent and quantitative test polyphenol content were determined using UV-Vis spectrophotometry method with Folin Ciocalteau reagent. Galic acid was used as comparator in this research. The result of qualitative test is all sample of brewed tea containing polyphenol. Polyphenol content sample A, B, C, D, and E with remaseration method were respectively 0,541; 0,557; 0,474; 0,557; and 0,428%(b/b).
本研究的目的是测定不同品牌包装茶中多酚的含量。样本分别采用5个样本。采用70%乙醇再发酵法提取包装茶中的多酚类化合物。定性试验采用FeCl3试剂,定量试验采用福林试剂紫外-可见分光光度法测定多酚含量。本研究以没食子酸为比较剂。定性检测结果为泡茶样品均含有多酚。复温法样品A、B、C、D、E的多酚含量分别为0.541;0557;0474;0557;和0428% (b / b)。
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引用次数: 0
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JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
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