Pub Date : 2022-12-20DOI: 10.53864/jifakfar.v3i2.152
S. Azizah, Mikhania Cristiningtyas Eryani
The objective of this research was to examine the antituberculosis activity of drug resistant stains using liquid culture extracts Streptomyces Kaempferia galanga rhizomes. The endophytes Streptomyces, there were KJ.3A, KJ3B, KJ.4, and KJ.11. Two resistant strain of Mycocacterium tuberculosis were used, there were HE strain which resistant to isoniazid dan etambutol and SR stainswhich resistant to streptomisin and rifampisin. The liquid culture extracts of Streptomyces endophytes was obtained from centrifugation method by growing Streptomyces colony into YMB media Antituberculosis activity was using Lowen-stein Jensen (LJ) methode after incubation for 8 weeks. The result showed that the four liquid culture extracts Streptomyces endophytes have not been able to inhibit the growth of Mycobacterium tuberculosis in both HE and SR strains
{"title":"AKTIVITAS ANTITUBERKULOSIS EKSTRAK KULTUR CAIR Streptomyces ENDOFIT RIMPANG Kaempferia galanga TERHADAP Mycobacterium tuberculosis RESISTEN","authors":"S. Azizah, Mikhania Cristiningtyas Eryani","doi":"10.53864/jifakfar.v3i2.152","DOIUrl":"https://doi.org/10.53864/jifakfar.v3i2.152","url":null,"abstract":"The objective of this research was to examine the antituberculosis activity of drug resistant stains using liquid culture extracts Streptomyces Kaempferia galanga rhizomes. The endophytes Streptomyces, there were KJ.3A, KJ3B, KJ.4, and KJ.11. Two resistant strain of Mycocacterium tuberculosis were used, there were HE strain which resistant to isoniazid dan etambutol and SR stainswhich resistant to streptomisin and rifampisin. The liquid culture extracts of Streptomyces endophytes was obtained from centrifugation method by growing Streptomyces colony into YMB media Antituberculosis activity was using Lowen-stein Jensen (LJ) methode after incubation for 8 weeks. The result showed that the four liquid culture extracts Streptomyces endophytes have not been able to inhibit the growth of Mycobacterium tuberculosis in both HE and SR strains","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89741134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-30DOI: 10.53864/jifakfar.v5i1.115
Dewi Riskha Nurmalasari
Acne is a skin disease caused by Propiniobacterium acne, and Staphylococcus aureus. To treat acne needed anti acne. In this reseacrh using medicinal plants as anti acne. These plants are efficious for anti acne. The genus Carica reported to contain papain enzym compounds. One type of plant has an anti acne activity with papain. Papain leaves (Carica papaya L) obtained from farmers Umbulrejo Umbulsari Jember. The papaya leavesis extracted with etanol 97%. Papaya leavest extract then made a solid soap, with 30% concentration of extract papaya leaves. The active inggredience is extract papaya leaves, NaOH as basa, oleum rosae as corigen odoris, and distilled water as a solvent. In this reseacrh, several physical quality tests of solid soap were carried out. The results of organoleptis test is this soap has a hard shape, the colours is light green, and the scent of soap smell rosae oil. The test results are recorded on the data collection sheet. Average of pH test showed 11, that entered in the range. The results of water content have an average of 8.2%, it shows that the soap meets the demand. The next test is the free fatty acid test results from the test that is 0.87%, the sign the results enter the range.Keywords: Papaya leaves, Solid soap, Physical quality test
{"title":"FORMULASI DAN UJI MUTU FISIK SABUN PADAT EKSTRAK DAUN PEPAYA (Carica papaya L.) 30% SEBAGAI ANTIJERAWAT","authors":"Dewi Riskha Nurmalasari","doi":"10.53864/jifakfar.v5i1.115","DOIUrl":"https://doi.org/10.53864/jifakfar.v5i1.115","url":null,"abstract":"Acne is a skin disease caused by Propiniobacterium acne, and Staphylococcus aureus. To treat acne needed anti acne. In this reseacrh using medicinal plants as anti acne. These plants are efficious for anti acne. The genus Carica reported to contain papain enzym compounds. One type of plant has an anti acne activity with papain. Papain leaves (Carica papaya L) obtained from farmers Umbulrejo Umbulsari Jember. The papaya leavesis extracted with etanol 97%. Papaya leavest extract then made a solid soap, with 30% concentration of extract papaya leaves. The active inggredience is extract papaya leaves, NaOH as basa, oleum rosae as corigen odoris, and distilled water as a solvent. In this reseacrh, several physical quality tests of solid soap were carried out. The results of organoleptis test is this soap has a hard shape, the colours is light green, and the scent of soap smell rosae oil. The test results are recorded on the data collection sheet. Average of pH test showed 11, that entered in the range. The results of water content have an average of 8.2%, it shows that the soap meets the demand. The next test is the free fatty acid test results from the test that is 0.87%, the sign the results enter the range.Keywords: Papaya leaves, Solid soap, Physical quality test","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87392640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-28DOI: 10.53864/jifakfar.v5i1.70
Wilda Ayu
Moringa (Moringa oleifera L.) is one of the plants that can be used both as food and medicine. The parts of this plant which often used as medicine are the seeds, leaves, and barks. The purpose of this study was to determine the total flavonoid of the ethanol extract of Moringa leaves by UV-Vis spectrophotometry. Extraction method for Moringa leaves using maceration method with 96% ethanol solvent.Furthermore, phytochemical screening was carried out on the ethanolic extract of Moringa leaves using the Thin Layer Chromatography (TLC) method and determination of total flavonoid content by UV-Vis spectrophotometry. The results of the research are Moringa contains alkaloids, flavonoids, tannins, free steroids/terpenoids, and steroids/terpenoid glycosides. Each gram of Moringa (Moringa oleifera, LamK) contain a total flavonoid compound content of 32.261 gQE/g extract with a percentage yield of 5,11%. The conclusion that Moringa leaves contain flavonoids with total flavonoid content of 32.261 μgQE / g extract.
{"title":"DETERMINATION OF TOTAL FLAVONOID LEVELS OF ETHANOL EXTRACT MORINGA LEAVES (Moringa oleifera, LamK) BY SPECTROPHOTOMETRY UV-Vis","authors":"Wilda Ayu","doi":"10.53864/jifakfar.v5i1.70","DOIUrl":"https://doi.org/10.53864/jifakfar.v5i1.70","url":null,"abstract":"Moringa (Moringa oleifera L.) is one of the plants that can be used both as food and medicine. The parts of this plant which often used as medicine are the seeds, leaves, and barks. The purpose of this study was to determine the total flavonoid of the ethanol extract of Moringa leaves by UV-Vis spectrophotometry. Extraction method for Moringa leaves using maceration method with 96% ethanol solvent.Furthermore, phytochemical screening was carried out on the ethanolic extract of Moringa leaves using the Thin Layer Chromatography (TLC) method and determination of total flavonoid content by UV-Vis spectrophotometry. The results of the research are Moringa contains alkaloids, flavonoids, tannins, free steroids/terpenoids, and steroids/terpenoid glycosides. Each gram of Moringa (Moringa oleifera, LamK) contain a total flavonoid compound content of 32.261 gQE/g extract with a percentage yield of 5,11%. The conclusion that Moringa leaves contain flavonoids with total flavonoid content of 32.261 μgQE / g extract.","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90903187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-28DOI: 10.53864/jifakfar.v5i1.62
Annisa Aulia Pridaningtias
Latar belakang penelitian: Bakteri yang beresiko menyebabkan infeksi adalah E. coli. penyakit yang dapat disebabkan oleh bakteri ini adalah penyakit diare, pneumonia, infeksi saluran kemih. Penelitian lain menunjukkan adanya aktivitas antibakteri pada daun mangga karena mangga memiliki senyawa kimia metabolit sekunder mangiferin yang terbukti memiliki aktivitas antibakteri. Mangga yang digunakan pada pennelitian ini adalah mangga Podang yang merupakan salah satu tanaman endemik di Indonesia yang tumbuh di Kediri Jawa Timur. Tujuan: Untuk mengetahui aktivitas antibakteri dari ekstrak metanol daun mangga podang (M. indica L.) terhadap bakteri Escherichia coli. Metode Penelitian: Daun mangga podang (Mangifera indica L.) dimaserasi dengan pelarut metanol. Uji aktivitas antibakteri menggunakan metode difusi disk atau kertas cakram dengan konsentrasi 6,25%, 12,5%, 25%, 50%, serta kelompok kontrol positif (kloramfenikol) dan kontrol negatif (DMSO 10%) dengan 3 kali pengulangan. Hasil dan Kesimpulan: Ekstrak metanol daun mangga podang memiliki aktivitas antibakteri terhadap bakteri E. coli dengan diameter zona hambat pada konsentrasi 6,25%, 12,5%, 25%, 50% yaitu sebesar 13,5 mm, 16,5 mm, 19,1 mm, 22,5 mm. Analisa data menggunkan Uji Kruskal-Wallis, Hasil analisa memperoleh nilai signifikan 0,006. Ekstrak metanol mangga podang memiliki aktivitas antibakteri terhadap bakteri Escherichia coli.Kata kunci: Mangga Podang, Mangifera indica L, Escherichia coli, Antibakteri
{"title":"UJI AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN MANGGA PODANG (Mangifera indica L.) TERHADAP BAKTERI ESCHERICHIA COLI","authors":"Annisa Aulia Pridaningtias","doi":"10.53864/jifakfar.v5i1.62","DOIUrl":"https://doi.org/10.53864/jifakfar.v5i1.62","url":null,"abstract":"Latar belakang penelitian: Bakteri yang beresiko menyebabkan infeksi adalah E. coli. penyakit yang dapat disebabkan oleh bakteri ini adalah penyakit diare, pneumonia, infeksi saluran kemih. Penelitian lain menunjukkan adanya aktivitas antibakteri pada daun mangga karena mangga memiliki senyawa kimia metabolit sekunder mangiferin yang terbukti memiliki aktivitas antibakteri. Mangga yang digunakan pada pennelitian ini adalah mangga Podang yang merupakan salah satu tanaman endemik di Indonesia yang tumbuh di Kediri Jawa Timur. Tujuan: Untuk mengetahui aktivitas antibakteri dari ekstrak metanol daun mangga podang (M. indica L.) terhadap bakteri Escherichia coli. Metode Penelitian: Daun mangga podang (Mangifera indica L.) dimaserasi dengan pelarut metanol. Uji aktivitas antibakteri menggunakan metode difusi disk atau kertas cakram dengan konsentrasi 6,25%, 12,5%, 25%, 50%, serta kelompok kontrol positif (kloramfenikol) dan kontrol negatif (DMSO 10%) dengan 3 kali pengulangan. Hasil dan Kesimpulan: Ekstrak metanol daun mangga podang memiliki aktivitas antibakteri terhadap bakteri E. coli dengan diameter zona hambat pada konsentrasi 6,25%, 12,5%, 25%, 50% yaitu sebesar 13,5 mm, 16,5 mm, 19,1 mm, 22,5 mm. Analisa data menggunkan Uji Kruskal-Wallis, Hasil analisa memperoleh nilai signifikan 0,006. Ekstrak metanol mangga podang memiliki aktivitas antibakteri terhadap bakteri Escherichia coli.Kata kunci: Mangga Podang, Mangifera indica L, Escherichia coli, Antibakteri","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83562819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-28DOI: 10.53864/jifakfar.v5i1.103
D. Nurmalasari
Acne is a skin disease caused by Propiniobacterium acne, and Staphylococcus aureus. To treat acne needed anti acne. In this reseacrh using medicinal plants as anti acne. These plants are efficious for anti acne. The genus Carica reported to contain papain enzym compounds. One type of plant has an anti acne activity with papain. Papain leaves (Carica papaya L) obtained from farmers Umbulrejo Umbulsari Jember. The papaya leavesis extracted with etanol 97%. Papaya leavest extract then made a solid soap, with 30% concentration of extract papaya leaves. The active inggredience is extract papaya leaves, NaOH as basa, oleum rosae as corigen odoris, and distilled water as a solvent. In this reseacrh, several physical quality tests of solid soap were carried out. The results of organoleptis test is this soap has a hard shape, the colours is light green, and the scent of soap smell rosae oil. The test results are recorded on the data collection sheet. Average of pH test showed 11, that entered in the range. The results of water content have an average of 8.2%, it shows that the soap meets the demand. The next test is the free fatty acid test results from the test that is 0.87%, the sign the results enter the range. Keywords: Papaya leaves, Solid soap, Physical quality test
{"title":"FORMULASI DAN UJI MUTU FISIK SABUN PADAT EKSTRAK DAUN PEPAYA (Carica papaya L.) 30% SEBAGAI ANTIJERAWAT","authors":"D. Nurmalasari","doi":"10.53864/jifakfar.v5i1.103","DOIUrl":"https://doi.org/10.53864/jifakfar.v5i1.103","url":null,"abstract":"Acne is a skin disease caused by Propiniobacterium acne, and Staphylococcus aureus. To treat acne needed anti acne. In this reseacrh using medicinal plants as anti acne. These plants are efficious for anti acne. The genus Carica reported to contain papain enzym compounds. One type of plant has an anti acne activity with papain. Papain leaves (Carica papaya L) obtained from farmers Umbulrejo Umbulsari Jember. The papaya leavesis extracted with etanol 97%. Papaya leavest extract then made a solid soap, with 30% concentration of extract papaya leaves. The active inggredience is extract papaya leaves, NaOH as basa, oleum rosae as corigen odoris, and distilled water as a solvent. In this reseacrh, several physical quality tests of solid soap were carried out. The results of organoleptis test is this soap has a hard shape, the colours is light green, and the scent of soap smell rosae oil. The test results are recorded on the data collection sheet. Average of pH test showed 11, that entered in the range. The results of water content have an average of 8.2%, it shows that the soap meets the demand. The next test is the free fatty acid test results from the test that is 0.87%, the sign the results enter the range. Keywords: Papaya leaves, Solid soap, Physical quality test","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85636603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-28DOI: 10.53864/jifakfar.v5i1.67
Iim Hasanah
Basil is traditional medicinal plants found a lot of in Indonesia. Basil leaves affication as analgetic, antiinflamantory, bacteria and antioxidant. This study aims to make an ointment stock that fulfills the requirements of preparation, knowing the physical properties of basil (Ocimum sanctum L) leaf juice. This research is an experimental research by making and evaluating basil leaves ointment preparations. The result of this research is that the juice of basil leaves (Ocimum sanctum L) containing the flavanoid compounds, tannins, and steroids and can be made as ointment stock that fulfill the requirements of physical properties evaluation. The organoleptic test included color, odor, and texture, from the three bases, it showed that the different types of basil leaf-squeezed ointment bases caused differences in the strength of the ointment preparations, while the color showed clear white and green. In the pH test, the three preparations had a pH of 5, the pH met the requirements for the pH of the topical preparation, which is between 4 – 6 which is the same as the normal pH of the skin. The homogeneity test of the three preparations showed that the preparations were homogeneous (no coarse lumps). The dispersion test has a dispersion of FI 3,5 cm, FII 5 cm, FIII 5,2 cm. Meanwhile the adhesion test is 4 seconds, 4,30 seconds, and 4,50 seconds. Keywords : Basil leaves, Evaluation tests, Ointments
{"title":"the formulation of the basil (Ocimum Basilicum Linn) leaf juiced ointment as a liniment","authors":"Iim Hasanah","doi":"10.53864/jifakfar.v5i1.67","DOIUrl":"https://doi.org/10.53864/jifakfar.v5i1.67","url":null,"abstract":"Basil is traditional medicinal plants found a lot of in Indonesia. Basil leaves affication as analgetic, antiinflamantory, bacteria and antioxidant. This study aims to make an ointment stock that fulfills the requirements of preparation, knowing the physical properties of basil (Ocimum sanctum L) leaf juice. This research is an experimental research by making and evaluating basil leaves ointment preparations. The result of this research is that the juice of basil leaves (Ocimum sanctum L) containing the flavanoid compounds, tannins, and steroids and can be made as ointment stock that fulfill the requirements of physical properties evaluation. The organoleptic test included color, odor, and texture, from the three bases, it showed that the different types of basil leaf-squeezed ointment bases caused differences in the strength of the ointment preparations, while the color showed clear white and green. In the pH test, the three preparations had a pH of 5, the pH met the requirements for the pH of the topical preparation, which is between 4 – 6 which is the same as the normal pH of the skin. The homogeneity test of the three preparations showed that the preparations were homogeneous (no coarse lumps). The dispersion test has a dispersion of FI 3,5 cm, FII 5 cm, FIII 5,2 cm. Meanwhile the adhesion test is 4 seconds, 4,30 seconds, and 4,50 seconds. Keywords : Basil leaves, Evaluation tests, Ointments","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75060788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-26DOI: 10.53864/jifakfar.v5i1.104
Asa Falahi
The purpose of this study was to determine the effect of variation concentration carbopol 934 934 to the characteristics of physical shampoo from anti-dandruff infusion of pandan leaves (Pandanus amaryllifolius roxb). Pre-experiment one shot case study was used as a research design. Variation in carbopol 934 concentration were 1% (F1), 1.5% (F2), and 2% (F3) The result stowed that variation concentration of carbopol 934 affect organoleptic shape and smell, pH, and viscosity of shampoo. But didn’t affect color, homogenity, and foam height oh shampoo. The viscosity of the shampoo increases with the increase in the concentration of carbopol 934 used.
{"title":"PENGARUH VARIASI KONSENTRASI CARBOPOL 934 SEBAGAI PENGENTAL TERHADAP SIFAT FISIK SEDIAAN SAMPO INFUSA DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.)","authors":"Asa Falahi","doi":"10.53864/jifakfar.v5i1.104","DOIUrl":"https://doi.org/10.53864/jifakfar.v5i1.104","url":null,"abstract":"The purpose of this study was to determine the effect of variation concentration carbopol 934 934 to the characteristics of physical shampoo from anti-dandruff infusion of pandan leaves (Pandanus amaryllifolius roxb). Pre-experiment one shot case study was used as a research design. Variation in carbopol 934 concentration were 1% (F1), 1.5% (F2), and 2% (F3) The result stowed that variation concentration of carbopol 934 affect organoleptic shape and smell, pH, and viscosity of shampoo. But didn’t affect color, homogenity, and foam height oh shampoo. The viscosity of the shampoo increases with the increase in the concentration of carbopol 934 used.","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72724360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-16DOI: 10.53864/jifakfar.v4i2.73
Dewi - Rashati
Diarrhea is influenced by several factors, including environmental conditions, community behavior, community services, nutrition, population, education which includes knowledge, and socio-economic conditions. Diarrhea is defecation in the form of liquid more than three times in one day and lasts for two or more days. The cause of diarrhea is mostly due to infection.Prevention of diarrhea that can be done is to continue breastfeeding, formula milk, and solid baby food, give ORS or sugar-salt solution to replace lost fluids, give foods that contain fiber, and give zinc for 10 consecutive days.The purpose of this study was to determine the level of mother's knowledge of the use of zinc in toddlers with diarrhea in Karang Pring RW 01, Sumber Jeruk village in the realm of knowing, understanding, and application. The method used is descriptive method with cross sectional analysis research design. In this study, the researcher used a validated questionnaire instrument. The sampling technique used total sampling and obtained 44 samples.Based on the results of data analysis, it was obtained that the percentage level of mother's knowledge on the use of zinc in toddlers with diarrhea in Karang Pring RW 01, Sumber Jeruk village for the July 2021 period in the tofu domain was 64.6%, the understanding domain was 74.2%, and in the application domain 72.7 %. The conclusion in this study is that the realm of knowing is categorized as sufficient, the realm of understanding is categorized as sufficient and in the realm of application it is categorized as sufficient. Keywords: Knowledge level, Diarrhea, zinc
腹泻受多种因素影响，包括环境条件、社区行为、社区服务、营养、人口、教育(包括知识)和社会经济条件。腹泻是以液体形式排便，一天超过三次，并持续两天或更长时间。腹泻的原因大多是由于感染。预防腹泻的方法是继续母乳喂养、配方奶和固体婴儿食品，用补液补液或糖盐溶液代替流失的液体，连续10天吃含纤维的食物，以及补锌。本研究的目的是确定在Sumber Jeruk村Karang spring rw01，母亲对腹泻幼儿锌使用的认识、理解和应用水平。采用的方法是描述性方法和横断面分析研究设计。在本研究中，研究者使用了一种有效的问卷调查工具。抽样技术采用全抽样，共获得44个样本。根据数据分析结果，得出2021年7月期间，在Sumber Jeruk村Karang spring RW 01，母亲对腹泻幼儿锌使用的知识在豆腐领域为64.6%，在理解领域为74.2%，在应用领域为72.7%。这项研究的结论是，认识领域被归类为充分领域，理解领域被归类为充分领域，应用领域被归类为充分领域。关键词:知识水平，腹泻，锌
{"title":"THE LEVEL OF MOTHER’S KNOWLEDGE ON THE USE OF ZINC IN TODDLERS WITH DIARRHEA IN KARANG PRING HAMLET, RW 01, SUMBER JERUK VILLAGE","authors":"Dewi - Rashati","doi":"10.53864/jifakfar.v4i2.73","DOIUrl":"https://doi.org/10.53864/jifakfar.v4i2.73","url":null,"abstract":" Diarrhea is influenced by several factors, including environmental conditions, community behavior, community services, nutrition, population, education which includes knowledge, and socio-economic conditions. Diarrhea is defecation in the form of liquid more than three times in one day and lasts for two or more days. The cause of diarrhea is mostly due to infection.Prevention of diarrhea that can be done is to continue breastfeeding, formula milk, and solid baby food, give ORS or sugar-salt solution to replace lost fluids, give foods that contain fiber, and give zinc for 10 consecutive days.The purpose of this study was to determine the level of mother's knowledge of the use of zinc in toddlers with diarrhea in Karang Pring RW 01, Sumber Jeruk village in the realm of knowing, understanding, and application. The method used is descriptive method with cross sectional analysis research design. In this study, the researcher used a validated questionnaire instrument. The sampling technique used total sampling and obtained 44 samples.Based on the results of data analysis, it was obtained that the percentage level of mother's knowledge on the use of zinc in toddlers with diarrhea in Karang Pring RW 01, Sumber Jeruk village for the July 2021 period in the tofu domain was 64.6%, the understanding domain was 74.2%, and in the application domain 72.7 %. The conclusion in this study is that the realm of knowing is categorized as sufficient, the realm of understanding is categorized as sufficient and in the realm of application it is categorized as sufficient. Keywords: Knowledge level, Diarrhea, zinc","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86504336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-16DOI: 10.53864/jifakfar.v4i2.116
Dewi - Rashati
Diarrhea is influenced by several factors, including environmental conditions, community behavior, community services, nutrition, population, education which includes knowledge, and socio-economic conditions. Diarrhea is defecation in the form of liquid more than three times in one day and lasts for two or more days. The cause of diarrhea is mostly due to infection.Prevention of diarrhea that can be done is to continue breastfeeding, formula milk, and solid baby food, give ORS or sugar-salt solution to replace lost fluids, give foods that contain fiber, and give zinc for 10 consecutive days.The purpose of this study was to determine the level of mother's knowledge of the use of zinc in toddlers with diarrhea in Karang Pring RW 01, Sumber Jeruk village in the realm of knowing, understanding, and application. The method used is descriptive method with cross sectional analysis research design. In this study, the researcher used a validated questionnaire instrument. The sampling technique used total sampling and obtained 44 samples.Based on the results of data analysis, it was obtained that the percentage level of mother's knowledge on the use of zinc in toddlers with diarrhea in Karang Pring RW 01, Sumber Jeruk village for the July 2021 period in the tofu domain was 64.6%, the understanding domain was 74.2%, and in the application domain 72.7 %. The conclusion in this study is that the realm of knowing is categorized as sufficient, the realm of understanding is categorized as sufficient and in the realm of application it is categorized as sufficient.Keywords: Knowledge level, Diarrhea, zinc
腹泻受多种因素影响，包括环境条件、社区行为、社区服务、营养、人口、教育(包括知识)和社会经济条件。腹泻是以液体形式排便，一天超过三次，并持续两天或更长时间。腹泻的原因大多是由于感染。预防腹泻的方法是继续母乳喂养、配方奶和固体婴儿食品，用补液补液或糖盐溶液代替流失的液体，连续10天吃含纤维的食物，以及补锌。本研究的目的是确定在Sumber Jeruk村Karang spring rw01，母亲对腹泻幼儿锌使用的认识、理解和应用水平。采用的方法是描述性方法和横断面分析研究设计。在本研究中，研究者使用了一种有效的问卷调查工具。抽样技术采用全抽样，共获得44个样本。根据数据分析结果，得出2021年7月期间，在Sumber Jeruk村Karang spring RW 01，母亲对腹泻幼儿锌使用的知识在豆腐领域为64.6%，在理解领域为74.2%，在应用领域为72.7%。这项研究的结论是，认识领域被归类为充分领域，理解领域被归类为充分领域，应用领域被归类为充分领域。关键词:知识水平，腹泻，锌
{"title":"THE LEVEL OF MOTHER’S KNOWLEDGE ON THE USE OF ZINC IN TODDLERS WITH DIARRHEA IN KARANG PRING HAMLET, RW 01, SUMBER JERUK VILLAGE","authors":"Dewi - Rashati","doi":"10.53864/jifakfar.v4i2.116","DOIUrl":"https://doi.org/10.53864/jifakfar.v4i2.116","url":null,"abstract":"Diarrhea is influenced by several factors, including environmental conditions, community behavior, community services, nutrition, population, education which includes knowledge, and socio-economic conditions. Diarrhea is defecation in the form of liquid more than three times in one day and lasts for two or more days. The cause of diarrhea is mostly due to infection.Prevention of diarrhea that can be done is to continue breastfeeding, formula milk, and solid baby food, give ORS or sugar-salt solution to replace lost fluids, give foods that contain fiber, and give zinc for 10 consecutive days.The purpose of this study was to determine the level of mother's knowledge of the use of zinc in toddlers with diarrhea in Karang Pring RW 01, Sumber Jeruk village in the realm of knowing, understanding, and application. The method used is descriptive method with cross sectional analysis research design. In this study, the researcher used a validated questionnaire instrument. The sampling technique used total sampling and obtained 44 samples.Based on the results of data analysis, it was obtained that the percentage level of mother's knowledge on the use of zinc in toddlers with diarrhea in Karang Pring RW 01, Sumber Jeruk village for the July 2021 period in the tofu domain was 64.6%, the understanding domain was 74.2%, and in the application domain 72.7 %. The conclusion in this study is that the realm of knowing is categorized as sufficient, the realm of understanding is categorized as sufficient and in the realm of application it is categorized as sufficient.Keywords: Knowledge level, Diarrhea, zinc","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88088097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-16DOI: 10.53864/jifakfar.v4i2.76
D. Nurmalasari
Diabetes mellitus (DM) is a disorder of the chronic metabolic system due to insufficiency of insulin function. DM is classified into two main categories, type 1 and type 2. The purpose of this study was to separate proteins using the SDS-PAGE method to determine the potential protein profile as a biomarker contained in the blood of type 2 DM patients, so that the results of the analysis can be used as an indicator of early detection of type 2 DM. This research is a true experimental research. The samples of this study were the blood of 20 patients with type 2 DM in Sukorejo Bangsalsari Village and the blood of 5 patients who non DM in Sukorejo Bangsalsari Village. sampling technique was randomized controlled trial, after the blood collection process, blood serum was then prepared at the Molecular Biology Laboratory, FMIPA UNEJ, then protein analysis was performed using the 1D-gel electrophoresis (SDS-PAGE) method. The results of protein characterization using SDS-PAGE analysis with blood serum of type 2 DM patients and serum of healthy people (non-patients) as negative controls, obtained protein bands that are less specific to potential targets, because the results of running are still not good, so it is not possible to know the biomarker protein profile in the blood of patients with type 2 DM in Sukorejo Bangsalsari Village, and the results of this analysis still cannot be used as an indicator for early detection of type 2 diabetes mellitus. Analysis of potential proteins profile as biomarkers using SDS-PAGE analysis has revealed three bands which had molecular weights of 28, 45 and 235 kDa. Keywords: Diabetes mellitus, Biomarker, SDS-PAGE
{"title":"PEMISAHAN PROTEIN DALAM DARAH PENDERITA DIABETES MELLITUS TIPE 2 UNTUK PENGEMBANGAN MOLEKUL BIOMARKER","authors":"D. Nurmalasari","doi":"10.53864/jifakfar.v4i2.76","DOIUrl":"https://doi.org/10.53864/jifakfar.v4i2.76","url":null,"abstract":"Diabetes mellitus (DM) is a disorder of the chronic metabolic system due to insufficiency of insulin function. DM is classified into two main categories, type 1 and type 2. The purpose of this study was to separate proteins using the SDS-PAGE method to determine the potential protein profile as a biomarker contained in the blood of type 2 DM patients, so that the results of the analysis can be used as an indicator of early detection of type 2 DM. This research is a true experimental research. The samples of this study were the blood of 20 patients with type 2 DM in Sukorejo Bangsalsari Village and the blood of 5 patients who non DM in Sukorejo Bangsalsari Village. sampling technique was randomized controlled trial, after the blood collection process, blood serum was then prepared at the Molecular Biology Laboratory, FMIPA UNEJ, then protein analysis was performed using the 1D-gel electrophoresis (SDS-PAGE) method. The results of protein characterization using SDS-PAGE analysis with blood serum of type 2 DM patients and serum of healthy people (non-patients) as negative controls, obtained protein bands that are less specific to potential targets, because the results of running are still not good, so it is not possible to know the biomarker protein profile in the blood of patients with type 2 DM in Sukorejo Bangsalsari Village, and the results of this analysis still cannot be used as an indicator for early detection of type 2 diabetes mellitus. Analysis of potential proteins profile as biomarkers using SDS-PAGE analysis has revealed three bands which had molecular weights of 28, 45 and 235 kDa. Keywords: Diabetes mellitus, Biomarker, SDS-PAGE","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88335740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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