Pub Date : 2021-08-12DOI: 10.53864/jifakfar.v4i1.47
R. Agustina, Amaliyah Nurul Hidayah
Pharmacy is one of the health service place that has product and service activities that are highly dependent on patient satisfaction. Patient satisfaction can be used as a benchmark for companies to develop their business in the future. The purpose of this study was to determine the level of patient satisfaction with pharmaceutical services at Kimia Farma Pharmacy Talangsari Jember. The type of this research was qualitative descriptive using cross sectional study. The population were patients who came to buy prescription or non-prescription drugs at the Kimia Farma Pharmacy Talangsari Jember in June 2020 with a total samples of 100 patients. The result showed that patient satisfaction to the services at Kimia Farma Pharmacy Talangsari Jember were quiet satisfied in reliability dimensions (60%) and tangible dimensions (55%) also in responsiveness dimensions (48%) and less satisfied in empathy dimensions (54%) and assurance dimensions (41%). It can be concluded that the level of patient satisfaction with pharmaceutical services at Kimia Farma Pharmacy Talangsari Jember were Keywords: level of satisfaction, quality of service
药房是卫生服务场所之一，其产品和服务活动高度依赖于患者满意度。患者满意度可以作为公司未来发展业务的基准。本研究的目的是确定患者满意度的药学服务在Kimia Farma药房Talangsari Jember。本研究采用横断面研究定性描述。人口是2020年6月在塔朗萨里jangsari Kimia Farma药房购买处方药或非处方药的患者，总共有100名患者。结果表明，患者对塔朗萨里Jember Kimia Farma Pharmacy的服务满意度在可靠性维度(60%)和有形维度(55%)和响应性维度(48%)上比较满意，而在同理心维度(54%)和保证维度(41%)上满意度较低。结果表明:患者对塔朗萨里Jember Kimia Farma药房药学服务的满意度为:满意度;服务质量
{"title":"LEVEL OF PATIENT SATISFACTION TOWARDS PHARMACY SERVICES IN KIMIA FARMA TALANGSARI PHARMACY","authors":"R. Agustina, Amaliyah Nurul Hidayah","doi":"10.53864/jifakfar.v4i1.47","DOIUrl":"https://doi.org/10.53864/jifakfar.v4i1.47","url":null,"abstract":"Pharmacy is one of the health service place that has product and service activities that are highly dependent on patient satisfaction. Patient satisfaction can be used as a benchmark for companies to develop their business in the future. The purpose of this study was to determine the level of patient satisfaction with pharmaceutical services at Kimia Farma Pharmacy Talangsari Jember. The type of this research was qualitative descriptive using cross sectional study. The population were patients who came to buy prescription or non-prescription drugs at the Kimia Farma Pharmacy Talangsari Jember in June 2020 with a total samples of 100 patients. The result showed that patient satisfaction to the services at Kimia Farma Pharmacy Talangsari Jember were quiet satisfied in reliability dimensions (60%) and tangible dimensions (55%) also in responsiveness dimensions (48%) and less satisfied in empathy dimensions (54%) and assurance dimensions (41%). It can be concluded that the level of patient satisfaction with pharmaceutical services at Kimia Farma Pharmacy Talangsari Jember were Keywords: level of satisfaction, quality of service","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75802381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-28DOI: 10.53864/jifakfar.v2i2.141
Agnis Pondinekaria Aditama
Gedi leaves (Abelmoschus manihot L. Medik) has been used empirically by the people of North Sulawesi to cure the disease. Flavonoids and steroids in Gedi leaves suspected to have anti-inflammatory effects. This Study aims to examine the anti-inflammatory effects of ethanol fraction from Gedi leaves (Abelmoschus manihot L. Medik) on edema of white males wistar foot induced with 1 % caragen, and to determine an effective dose of fraction to decrease the edema volume of Rat foot. The test was done using Rat Hind Paw Edeme or esthablished an artificial inflammation in left foot of white male rats. The treatments were carried out on five groups, the positive control group was administered with diclofenac sodium, the negative control group was administered with CMC Na 0,5 % solution, and the fraction groups were administered with 12 mg/Kg BB, 27 mg/Kg BB, 54 mg/Kg BB. Edema volume were measured every hour for 5 hours using a pletismometer. The average of edema volume (mL) and time (hour) were used to calculate the percentage of anti-inflammatory on each group compared to the negative control group. Obtained data were analyzed by one-way ANOVA followed by LSD test with confident level was 0,05. The result of this study indicate that gedi leaves can reduce edema volume of rat foot that induced with 1 % caragen and anti-inflammatory activity showed in ethanol fraction from Gedi leaves 12 mg/Kg BB by 55,2 %, 27 mg/Kg BB by 64,4% and 54 mg/Kg BB by 62,2%.
葛地叶(Abelmoschus manihot L. Medik)已经被北苏拉威西岛的人们用来治疗这种疾病。葛地叶中的黄酮类和甾类化合物疑似具有抗炎作用。本研究旨在研究葛地叶乙醇提取物对1% caragen诱导的白种雄性大鼠足水肿的抗炎作用，并确定其减少大鼠足水肿体积的有效剂量。实验采用大鼠后爪提取物或在白色雄性大鼠左脚建立人工炎症。治疗分为5组，阳性对照组给予双氯芬酸钠治疗，阴性对照组给予CMC Na 0.5%溶液治疗，各部分组分别给予12 mg/Kg BB、27 mg/Kg BB、54 mg/Kg BB治疗。每隔一小时用压度计测量水肿量，持续5小时。以水肿体积(mL)和时间(h)的平均值计算各组与阴性对照组相比抗炎作用的百分比。所得资料采用单因素方差分析，再进行LSD检验，置信水平为0,05。结果表明，葛地叶对1%豆角素诱导的大鼠足部水肿有明显的抑制作用，葛地叶乙醇提取物12 mg/Kg BB的抗炎作用为55.2%，27 mg/Kg BB的抗炎作用为64,4%，54 mg/Kg BB的抗炎作用为62,2%。
{"title":"AKTIVITAS ANTIINFLAMASI FRAKSI ETANOL DAUN GEDI (Abelmoschus manihot L. Medik) PADA TIKUS PUTIH GALUR WISTAR","authors":"Agnis Pondinekaria Aditama","doi":"10.53864/jifakfar.v2i2.141","DOIUrl":"https://doi.org/10.53864/jifakfar.v2i2.141","url":null,"abstract":"Gedi leaves (Abelmoschus manihot L. Medik) has been used empirically by the people of North Sulawesi to cure the disease. Flavonoids and steroids in Gedi leaves suspected to have anti-inflammatory effects. This Study aims to examine the anti-inflammatory effects of ethanol fraction from Gedi leaves (Abelmoschus manihot L. Medik) on edema of white males wistar foot induced with 1 % caragen, and to determine an effective dose of fraction to decrease the edema volume of Rat foot. The test was done using Rat Hind Paw Edeme or esthablished an artificial inflammation in left foot of white male rats. The treatments were carried out on five groups, the positive control group was administered with diclofenac sodium, the negative control group was administered with CMC Na 0,5 % solution, and the fraction groups were administered with 12 mg/Kg BB, 27 mg/Kg BB, 54 mg/Kg BB. Edema volume were measured every hour for 5 hours using a pletismometer. The average of edema volume (mL) and time (hour) were used to calculate the percentage of anti-inflammatory on each group compared to the negative control group. Obtained data were analyzed by one-way ANOVA followed by LSD test with confident level was 0,05. The result of this study indicate that gedi leaves can reduce edema volume of rat foot that induced with 1 % caragen and anti-inflammatory activity showed in ethanol fraction from Gedi leaves 12 mg/Kg BB by 55,2 %, 27 mg/Kg BB by 64,4% and 54 mg/Kg BB by 62,2%.","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"212 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76211492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-28DOI: 10.53864/jifakfar.v2i1.15
Dewi rashati, Amirul Fauziah
This research is aims to determine the effect of variation concentration starch Zea mays (L) as disintegration agent in wet granulation to physical characteristics paracetamo. This research used eperimental method by one shot case study. Paracetamol as active ingredient, starch zea mays (L)as desintegrant agent, PVPK30 as binding agent, avicel as filler and Mg stearat as lubricants. The result of SPSS showed significant (p0,05), that means no difference in the three formulation. The first test is weight uniformity show that from column A and B qualify weight requirement range, hardness test. Showed significant (p0,05) that means nodifference in the three formulation. Friability test showed significant (p 0,05) the last is disintegration time test showed that significant (P0,05) no difference in the three formulation. The research of physic characteristic of the tablet showed that hardness test and time test not qualif. Analysis SPSS showed (p0,05) no difference in the three formulation and amilum had no effect on physical test of paracetamol tablet.Keywords: zea mays (L),paracetamol,physicial characteristic
{"title":"PENGARUH VARIASI KONSENTRASI AMILUM Zea mays (L) SEBAGAI BAHAN PENGHANCUR SECARA GRANULASI BASAH TERHADAP SIFAT FISIK TABLET PARASETAMOL","authors":"Dewi rashati, Amirul Fauziah","doi":"10.53864/jifakfar.v2i1.15","DOIUrl":"https://doi.org/10.53864/jifakfar.v2i1.15","url":null,"abstract":"This research is aims to determine the effect of variation concentration starch Zea mays (L) as disintegration agent in wet granulation to physical characteristics paracetamo. This research used eperimental method by one shot case study. Paracetamol as active ingredient, starch zea mays (L)as desintegrant agent, PVPK30 as binding agent, avicel as filler and Mg stearat as lubricants. The result of SPSS showed significant (p0,05), that means no difference in the three formulation. The first test is weight uniformity show that from column A and B qualify weight requirement range, hardness test. Showed significant (p0,05) that means nodifference in the three formulation. Friability test showed significant (p 0,05) the last is disintegration time test showed that significant (P0,05) no difference in the three formulation. The research of physic characteristic of the tablet showed that hardness test and time test not qualif. Analysis SPSS showed (p0,05) no difference in the three formulation and amilum had no effect on physical test of paracetamol tablet.Keywords: zea mays (L),paracetamol,physicial characteristic","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82717702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-28DOI: 10.53864/jifakfar.v2i1.17
Kukuh Judy Handojo,Pradanu Satria Rakhmanta,Diyan Ajeng R
PBF services in Lumajang region need to improve the quality of service, includingdelivery time often exceeds the time that had been promised, complaints regarding medication errors and difficulty getting accountability, the price has changed in a short time, and the service was not constant. The purpose of this study was to determine the level of drug store Lumajang region against drug distribution by PBF in tangible dimension (direct evidence), reliablity (reliability), responsivines (responsiveness),assurance (assurance), empathy (caring). Samples were selected in this research is all drug store in Lumajang totaling 30 pharmacies. The research design in this study is descriptive by using survey method.Based on the data collection process,there were only 30 drug store that are willing to be respondenden has qualified for data processing and it can be concluded that the level of satisfaction Pharmacy Lumajang region on tangible dimension (direct evidence) of 86.24%, expressed satisfaction,reliability dimension (reliability) by 80%, otherwise satisfactory, dimensions responsiviness (responsiveness) of 75.84%, expressed quite satisfactory, dimensions assurance (guarantee) amounting to 86.11%, declared satisfactory, the dimensions of empathy (caring) amounted to 86.94%, otherwise satisfactory. Based on the above data,it needs to be evaluated in five dimensions, from the evaluation it would appear that satisfaction level of drug store in Lumajang to PBF service (drug distribution)reach 83,02% and including the satisfactory category .Keywords: Level of satisfaction - Drugs distribution – PBF
{"title":"TINGKAT KEPUASAN APOTEK DI WILAYAH LUMAJANG TERHADAP DISTRIBUSI OBAT OLEH PEDAGANG BESAR FARMASI","authors":"Kukuh Judy Handojo,Pradanu Satria Rakhmanta,Diyan Ajeng R","doi":"10.53864/jifakfar.v2i1.17","DOIUrl":"https://doi.org/10.53864/jifakfar.v2i1.17","url":null,"abstract":"PBF services in Lumajang region need to improve the quality of service, includingdelivery time often exceeds the time that had been promised, complaints regarding medication errors and difficulty getting accountability, the price has changed in a short time, and the service was not constant. The purpose of this study was to determine the level of drug store Lumajang region against drug distribution by PBF in tangible dimension (direct evidence), reliablity (reliability), responsivines (responsiveness),assurance (assurance), empathy (caring). Samples were selected in this research is all drug store in Lumajang totaling 30 pharmacies. The research design in this study is descriptive by using survey method.Based on the data collection process,there were only 30 drug store that are willing to be respondenden has qualified for data processing and it can be concluded that the level of satisfaction Pharmacy Lumajang region on tangible dimension (direct evidence) of 86.24%, expressed satisfaction,reliability dimension (reliability) by 80%, otherwise satisfactory, dimensions responsiviness (responsiveness) of 75.84%, expressed quite satisfactory, dimensions assurance (guarantee) amounting to 86.11%, declared satisfactory, the dimensions of empathy (caring) amounted to 86.94%, otherwise satisfactory. Based on the above data,it needs to be evaluated in five dimensions, from the evaluation it would appear that satisfaction level of drug store in Lumajang to PBF service (drug distribution)reach 83,02% and including the satisfactory category .Keywords: Level of satisfaction - Drugs distribution – PBF","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74009265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-28DOI: 10.53864/jifakfar.v3i1.38
Siti Nur Azizah, Mikhania Cristiningtyas Eryani
The objective of this research was to obtain Endophitic Streptomyces from some medical plants which have antituberculosis effect and also to test its antitubercullosis activity againts sensitive stain of Mycobacterium tuberculosis. Medicinal plants used in this study were Kaemferia galanga, Hibiscus sabdariffa and Piper cronatum. Streptomyces was isolated using two different media namely Humic Acid Vitamin (HV) agar and HV with plant extract, and purified on Yeast Malt Agar (YMA) medium. Morphological characterization of Streptomyces obtained was observed including aerial mycelium and substrate mycelium, pigmentation, and colony surface. A total of 5 endophitic Streptomyces genus were obtained from medicinal plant. Isolates K.J3A, K.J3B, K.J4 and K.J11 from Kaemferia galanga radix, S.MJ1 from Piper cronatum folium. Streptomyces was not found from Hibiscus sabdariffa calyx. Each isolate had variety of characteristics which could be seen in aerial mass color, substrate mass color, and pigmentation. Antitubercullosis activity showed that total of 5 endophitic Streptomyces were not capable to inhibit the growth sensitive stain of M. tubercullosis.Keywods: Antituberculosis, endophitic actinomycetes, Kaemferia galanga, Hibiscus sabdariffa
{"title":"POTENSI STREPTOMYCES ENDOFIT RIMPANG KENCUR DAN DAUN SIRIH MERAH SEBAGAI ANTITUBERKULOSIS PADA MYCOBACTERIUM TUBERCULOSIS GALUR SENSITIF","authors":"Siti Nur Azizah, Mikhania Cristiningtyas Eryani","doi":"10.53864/jifakfar.v3i1.38","DOIUrl":"https://doi.org/10.53864/jifakfar.v3i1.38","url":null,"abstract":"The objective of this research was to obtain Endophitic Streptomyces from some medical plants which have antituberculosis effect and also to test its antitubercullosis activity againts sensitive stain of Mycobacterium tuberculosis. Medicinal plants used in this study were Kaemferia galanga, Hibiscus sabdariffa and Piper cronatum. Streptomyces was isolated using two different media namely Humic Acid Vitamin (HV) agar and HV with plant extract, and purified on Yeast Malt Agar (YMA) medium. Morphological characterization of Streptomyces obtained was observed including aerial mycelium and substrate mycelium, pigmentation, and colony surface. A total of 5 endophitic Streptomyces genus were obtained from medicinal plant. Isolates K.J3A, K.J3B, K.J4 and K.J11 from Kaemferia galanga radix, S.MJ1 from Piper cronatum folium. Streptomyces was not found from Hibiscus sabdariffa calyx. Each isolate had variety of characteristics which could be seen in aerial mass color, substrate mass color, and pigmentation. Antitubercullosis activity showed that total of 5 endophitic Streptomyces were not capable to inhibit the growth sensitive stain of M. tubercullosis.Keywods: Antituberculosis, endophitic actinomycetes, Kaemferia galanga, Hibiscus sabdariffa","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"84 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84308666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-28DOI: 10.53864/jifakfar.v2i1.20
Rosida, Diyan Ajeng RA
Antioksidan merupakan senyawa yang mampu menghambat oksidasi molekul lain. Tubuh tidak mempunyai sistem pertahanan antioksidatif yang berlebihan, sehingga tubuh membutuhkan antioksidan eksogen. Kekhawatiran terhadap efek samping antioksidan sintetik menjadikan antioksidan alami menjadi alternatif yang dipilih. Flavonoid merupakan senyawa fenolat (hidroksil fenolik) yang mampu bertindak sebagai antioksidan dan umumnya terdapat pada tanaman. Salah satu limbah tanaman yang mempunyai kandungan flavonoid adalah kulit buah pisang (Musa acuminata). Tujuan dari penelitian ini adalah untuk menetapkan kadar flavonoid total dan melakukan pengujian aktivitas antioksidan kulit buah pisang menggunakan diphenyl picryl hydrazil hydrate (DPPH) sebagai radikal bebas. Metode ekstraksi yang digunakan adalah remaserasi dengan pelarut etanol 96%. Penetapan kadar flavonoid total menggunakan katekin sebagai standar dan pengujian DPPH menggunakan metode spetrofotometri. Hasil penelitian menunjukkan kandungan flavonoid total ekstrak etanol kulit buah pisang sebesar 0,79 ± 0,03 %b/b, aktivitas antioksidan tertinggi dalam IC50 terhadap DPPH sebesar 70,41 mg/L.Kata Kunci : kulit buah pisang, flavonoid total, aktivitas antioksidan, IC50
抗氧化剂是一种能抑制其他分子氧化的化合物。身体没有多余的抗氧化剂防御系统，所以身体需要外来的抗氧化剂。对抗氧化剂和合成作用的担忧使天然抗氧化剂成为选定的替代品。类黄酮是一种表型化合物，具有抗氧化剂的作用，通常存在于植物中。一种含有黄酮的植物废物是香蕉果皮(摩西acuminata)。这项研究的目的是确定总黄酮水平，并使用二恶英(DPPH)作为自由基测试香蕉果的抗氧化活性。提取方法与乙醇溶剂96%相匹配。对总类黄酮的测定采用了氯丁作为标准，并采用了光谱测定方法进行了DPPH测试。研究结果显示完全类黄酮含量大小的香蕉皮乙醇提取物0.79±0.03 % b - b,螺旋藻中最高的抗氧化能力对DPPH 70.41万mg / L。关键词:香蕉果皮，全黄酮，抗氧化剂活性，IC50
{"title":"PENENTUAN AKTIVITAS ANTIOKSIDAN DAN KADAR FENOL TOTAL PADA EKSTRAK KULIT BUAH PISANG (Musa acuminata Colla)","authors":"Rosida, Diyan Ajeng RA","doi":"10.53864/jifakfar.v2i1.20","DOIUrl":"https://doi.org/10.53864/jifakfar.v2i1.20","url":null,"abstract":"Antioksidan merupakan senyawa yang mampu menghambat oksidasi molekul lain. Tubuh tidak mempunyai sistem pertahanan antioksidatif yang berlebihan, sehingga tubuh membutuhkan antioksidan eksogen. Kekhawatiran terhadap efek samping antioksidan sintetik menjadikan antioksidan alami menjadi alternatif yang dipilih. Flavonoid merupakan senyawa fenolat (hidroksil fenolik) yang mampu bertindak sebagai antioksidan dan umumnya terdapat pada tanaman. Salah satu limbah tanaman yang mempunyai kandungan flavonoid adalah kulit buah pisang (Musa acuminata). Tujuan dari penelitian ini adalah untuk menetapkan kadar flavonoid total dan melakukan pengujian aktivitas antioksidan kulit buah pisang menggunakan diphenyl picryl hydrazil hydrate (DPPH) sebagai radikal bebas. Metode ekstraksi yang digunakan adalah remaserasi dengan pelarut etanol 96%. Penetapan kadar flavonoid total menggunakan katekin sebagai standar dan pengujian DPPH menggunakan metode spetrofotometri. Hasil penelitian menunjukkan kandungan flavonoid total ekstrak etanol kulit buah pisang sebesar 0,79 ± 0,03 %b/b, aktivitas antioksidan tertinggi dalam IC50 terhadap DPPH sebesar 70,41 mg/L.Kata Kunci : kulit buah pisang, flavonoid total, aktivitas antioksidan, IC50","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91536614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-28DOI: 10.53864/jifakfar.v1i2.12
Mikhania Christiningtyas Eryani, Dewi Rashati
Zaitun tree (Olea europaea) comes from the Middle East and widely grown in Asia. The fruit and oil extraction widely used as food and medicine. The oil derived from olives is known as olive oil. Olive oil can be used for skin emolient. The aims of this study was to determine olive oil variation concentration to liquid soap softness. The soap was made with varying olive oil concentration (20% known as F1, 30% known as F2 and 40% known as F3). True experimental design with The Posttest Only Experiment was used as the study design. Evaluation of the soap including organoleptic test, pH, spesific gravity, free alkali assay, and responden emolient test. Responden emolient test was taken from 20 responden who has given questioner. The data from emolient test study was calculate by Kruskal Wallis test. The organoleptic test result showed that all formula showed liquid green, homogen, and jasmine odor. pH from F1, F2 and F3 were 10,39; 9,75 dan 9,34 respectively. The spesicic gravity from F1, F2 and F3 were 1,648%; 1,441% dan 0,863 % respectively. The free alkali from F1, F2 and F3 were 0,032%; 0,08% dan 0,064% respectively. The responden emolient test showed that F1 was soft, F2 was midle soft and F3 was very soft.Keywords: oilive oil, soap, softness
{"title":"PENGARUH VARIASI KONSENTRASI MINYAK ZAITUN (OLIVE OIL) TERHADAP KELEMBUTAN SABUN CAIR","authors":"Mikhania Christiningtyas Eryani, Dewi Rashati","doi":"10.53864/jifakfar.v1i2.12","DOIUrl":"https://doi.org/10.53864/jifakfar.v1i2.12","url":null,"abstract":"Zaitun tree (Olea europaea) comes from the Middle East and widely grown in Asia. The fruit and oil extraction widely used as food and medicine. The oil derived from olives is known as olive oil. Olive oil can be used for skin emolient. The aims of this study was to determine olive oil variation concentration to liquid soap softness. The soap was made with varying olive oil concentration (20% known as F1, 30% known as F2 and 40% known as F3). True experimental design with The Posttest Only Experiment was used as the study design. Evaluation of the soap including organoleptic test, pH, spesific gravity, free alkali assay, and responden emolient test. Responden emolient test was taken from 20 responden who has given questioner. The data from emolient test study was calculate by Kruskal Wallis test. The organoleptic test result showed that all formula showed liquid green, homogen, and jasmine odor. pH from F1, F2 and F3 were 10,39; 9,75 dan 9,34 respectively. The spesicic gravity from F1, F2 and F3 were 1,648%; 1,441% dan 0,863 % respectively. The free alkali from F1, F2 and F3 were 0,032%; 0,08% dan 0,064% respectively. The responden emolient test showed that F1 was soft, F2 was midle soft and F3 was very soft.Keywords: oilive oil, soap, softness","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84759086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-28DOI: 10.53864/jifakfar.v2i2.27
Hadi Barru Hakam Fajar Siddiq, Dewi Rashati, Farida Suryaningsih
The N-(4t-Butylbenzoyl)-p-Aminophenol compound was a synthesis compound between p-aminophenol and 4t-Butylbenzoyl chloride by using H2SO4 catalyst. The addition of H2SO4 catalyst purposed to accelerate the rate of rection in the synthesis of the compound and increased yield of product. The N-(4t-Butylbenzoil)-p-Aminophenol compound is beneficial as an antiinflammatory analgesic. This research were proposed to determine characteristics of the anti-inflammatory analgesic synthesis of N-(4t-Butylbenzoyl)-p-Aminophenol compound by using H2SO4 catalyst. Characterization conducted in this research were physical and chemical characterization. The physical characterization were organoleptic test, crystal form test and melting point test. While chemical characterization were UV-Vis spectrophotometry and FTIR. Result of organoleptic test showed sample had powder form, white-gray colour and not taste. Melting point of N-(4t-Butylbenzoyl)-p-Aminophenol compound was 193.33 °C. The optimum wavelength of UV-Vis spectrophotometry got 2 peaks at the wavelengths 290 and 295 nm. The result of FTIR showed that N-(4t-Butylbenzoyl)-p-Aminophenol compound had peaks.Keywords: N-(4t-butyl benzoil)-p-aminophenol, catalyst
{"title":"KARAKTERISASI SENYAWA ANALGETIKA-ANTIINFLAMASI N-(4t-BUTILBENZOIL)-p-AMINOFENOL YANG DISINTISES DENGAN KATALIS ASAM","authors":"Hadi Barru Hakam Fajar Siddiq, Dewi Rashati, Farida Suryaningsih","doi":"10.53864/jifakfar.v2i2.27","DOIUrl":"https://doi.org/10.53864/jifakfar.v2i2.27","url":null,"abstract":"The N-(4t-Butylbenzoyl)-p-Aminophenol compound was a synthesis compound between p-aminophenol and 4t-Butylbenzoyl chloride by using H2SO4 catalyst. The addition of H2SO4 catalyst purposed to accelerate the rate of rection in the synthesis of the compound and increased yield of product. The N-(4t-Butylbenzoil)-p-Aminophenol compound is beneficial as an antiinflammatory analgesic. This research were proposed to determine characteristics of the anti-inflammatory analgesic synthesis of N-(4t-Butylbenzoyl)-p-Aminophenol compound by using H2SO4 catalyst. Characterization conducted in this research were physical and chemical characterization. The physical characterization were organoleptic test, crystal form test and melting point test. While chemical characterization were UV-Vis spectrophotometry and FTIR. Result of organoleptic test showed sample had powder form, white-gray colour and not taste. Melting point of N-(4t-Butylbenzoyl)-p-Aminophenol compound was 193.33 °C. The optimum wavelength of UV-Vis spectrophotometry got 2 peaks at the wavelengths 290 and 295 nm. The result of FTIR showed that N-(4t-Butylbenzoyl)-p-Aminophenol compound had peaks.Keywords: N-(4t-butyl benzoil)-p-aminophenol, catalyst","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89642168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-28DOI: 10.53864/jifakfar.v1i2.9
Dewi Rashati, Mikhania Christiningtyas Eryani
The Aims of this study was to determine effect of HPMC concentration variation to etanol extract Sauropus androgynus (L) Merr shampoo physical properties. True experimental laboratories design was used as design study. Shampoo was formulated in three formulation which used HPMC variation consentration were F1 (1%), F2 (2%) , F3 (3%). Shampoo was evaluated physical properties included organoleptic, pH, viscosity, foam forming, and stability test at 6oC, 300C and 40oC. Organoleptic test was observed by visual observation. pH, viscosity, foam forming, and stability test from three formulation were observed by one way anova statistic. The result showed that HPMC concentration variation didn’t influence to physical properties foam forming and pH shampoo but there had influence to physical properties viscosity. All formulation of formulation unstable during 6 weeks storage.Keywords: Shampoo, etanol extract Sauropus androgynus (L) Merr, HPMC
{"title":"PENGARUH VARIASI KONSENTRASI HPMC TERHADAP MUTU FISIK DAN STABILITAS SEDIAAN SHAMPO EKSTRAK ETANOL DAUN KATUK (Sauropus androgynus (L) Merr)","authors":"Dewi Rashati, Mikhania Christiningtyas Eryani","doi":"10.53864/jifakfar.v1i2.9","DOIUrl":"https://doi.org/10.53864/jifakfar.v1i2.9","url":null,"abstract":"The Aims of this study was to determine effect of HPMC concentration variation to etanol extract Sauropus androgynus (L) Merr shampoo physical properties. True experimental laboratories design was used as design study. Shampoo was formulated in three formulation which used HPMC variation consentration were F1 (1%), F2 (2%) , F3 (3%). Shampoo was evaluated physical properties included organoleptic, pH, viscosity, foam forming, and stability test at 6oC, 300C and 40oC. Organoleptic test was observed by visual observation. pH, viscosity, foam forming, and stability test from three formulation were observed by one way anova statistic. The result showed that HPMC concentration variation didn’t influence to physical properties foam forming and pH shampoo but there had influence to physical properties viscosity. All formulation of formulation unstable during 6 weeks storage.Keywords: Shampoo, etanol extract Sauropus androgynus (L) Merr, HPMC","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88676474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-28DOI: 10.53864/jifakfar.v2i2.28
Siti Nur Azizah, Rosida
Limbah cangkang udang mengandung kitin yang tinggi yaitu sekitar 17-40%. Kitin tersebut dapat digunakan sebagai substat pertumbuhan bakteri kitinolitik yaitu S.marcescens KAHN 15.12. Bakteri tersebut akan mensekresikan enzim kitinase untuk mendegradasi kitin sebagai media pertumbuhannya hingga menghasilkan monomer N-asetil glukosamin (GlcNac). N-asetil glukosamin dapat dimanfaatkan sebagai bahan sediaan suplemen osteoartritis. Penelitian ini bertujuan untuk memproduksi GlcNac hasil hidrolisis kitin cangkang udang menggunakan kitinase Serratia marcescens KAHN.15.12. Hasil konfirmasi aktivitas kitinolitik menggunakan media selektif yaitu agar koloidal kitin 0,3% menunjukkan bahwa Serratia marcescens KAHN 15.12 memiliki index kitinolitik sebesar 2,3 yang ditunjukkan dengan adanya zona bening disekitar koloni. Hasil optimasi perbedaan konsentrasi media produksi menunjukkan bahwa tepung cangkang udang 2% menghasilkan kadar GlcNac tertinggi yaitu sebesar 376,35 μg/ml setelah diuji dengan metode kolorimetri menggunakan reagen shcales pada panjang gelombang 420nm. Berdasarkan hasil tersebut menunjukkan bahwa setiap hidrolisis 1 gram tepung cangkang udang yang mengandung 18,7% kitin akan menghasilkan sebesar 70,54 mg GlcNAc.Kata Kunci: N-asetil glukosamin, kitinase, Serratia marcescens
{"title":"OPTIMASI HIDROLISIS MEDIA PRODUKSI CANGKANG UDANG MENGGUNAKAN KITINASE SERRATIA MARCESCENS KAHN.15.12 TERHADAP KADAR N-ASETIL GLUKOSAMIN SEBAGAI BAHAN SEDIAAN","authors":"Siti Nur Azizah, Rosida","doi":"10.53864/jifakfar.v2i2.28","DOIUrl":"https://doi.org/10.53864/jifakfar.v2i2.28","url":null,"abstract":"Limbah cangkang udang mengandung kitin yang tinggi yaitu sekitar 17-40%. Kitin tersebut dapat digunakan sebagai substat pertumbuhan bakteri kitinolitik yaitu S.marcescens KAHN 15.12. Bakteri tersebut akan mensekresikan enzim kitinase untuk mendegradasi kitin sebagai media pertumbuhannya hingga menghasilkan monomer N-asetil glukosamin (GlcNac). N-asetil glukosamin dapat dimanfaatkan sebagai bahan sediaan suplemen osteoartritis. Penelitian ini bertujuan untuk memproduksi GlcNac hasil hidrolisis kitin cangkang udang menggunakan kitinase Serratia marcescens KAHN.15.12. Hasil konfirmasi aktivitas kitinolitik menggunakan media selektif yaitu agar koloidal kitin 0,3% menunjukkan bahwa Serratia marcescens KAHN 15.12 memiliki index kitinolitik sebesar 2,3 yang ditunjukkan dengan adanya zona bening disekitar koloni. Hasil optimasi perbedaan konsentrasi media produksi menunjukkan bahwa tepung cangkang udang 2% menghasilkan kadar GlcNac tertinggi yaitu sebesar 376,35 μg/ml setelah diuji dengan metode kolorimetri menggunakan reagen shcales pada panjang gelombang 420nm. Berdasarkan hasil tersebut menunjukkan bahwa setiap hidrolisis 1 gram tepung cangkang udang yang mengandung 18,7% kitin akan menghasilkan sebesar 70,54 mg GlcNAc.Kata Kunci: N-asetil glukosamin, kitinase, Serratia marcescens","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75794618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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