Pub Date : 2022-12-31DOI: 10.36326/kjvs/2022/v13i210286
Karar Mohammed AL-Zuwayni, K. Khudair
This study was carried out to investigate the effect of acarbose or combination of acarbose and Oleuropein (OLEU) on glycemic index and antioxidant status of male rats exposed to high fructose(40%) and 0.05% hydrogen peroxide H2O2 Thirty-two adult male rats were randomly divided into four equal groups: control group (CC); T1( HFr-H2O2) group were exposed to high fructose (40%) in drinking water and given orally 0.05% H2O2; T2: 30mg/kg of acarbose were given orally to HF-H2O2 treated rats, while combination of acarbose and Oleuropein (50mg/kg. B.W) were given orally to (HFr-H2O2) treated rats in group T3. Blood samples were taken at zero time and after two months of the experiment for measuring some parameters related to glycemic index and antioxidant status. The results declared an elevation in the glycemic index (insulin and glucose concentrations and insulin resistance (IR)) and malondialdehyde (MDA) and depression in glutathione (GSH) concentrations in T1 group at the end of experiment comparing to other treated groups. Antioxidant status and glycemic index were restored after acarbose or combination of acarbose and Oleuropein treatment characterized by significant depression of serum glucose, insulin concentrations and IR, and alleviation of oxidative stress clarified by depression of serum MDA with elevation in serum GSH concentration in groups T2 and T3. On conclusion, the current study documented the oxidative and hyperglycemic effect of fructose and H2O2 that can be ameliorating by oral administration of acarbose. Besides, combination of OLUE supplement with acarbose possessed additive effects.
{"title":"Effect of Acarbose and olive leaf extract (Oleuropein) on Glycemic index and Antioxidant Status in High Fructose and H2O2 Exposed Rats (Parts-II)","authors":"Karar Mohammed AL-Zuwayni, K. Khudair","doi":"10.36326/kjvs/2022/v13i210286","DOIUrl":"https://doi.org/10.36326/kjvs/2022/v13i210286","url":null,"abstract":"This study was carried out to investigate the effect of acarbose or combination of acarbose and Oleuropein (OLEU) on glycemic index and antioxidant status of male rats exposed to high fructose(40%) and 0.05% hydrogen peroxide H2O2 Thirty-two adult male rats were randomly divided into four equal groups: control group (CC); T1( HFr-H2O2) group were exposed to high fructose (40%) in drinking water and given orally 0.05% H2O2; T2: 30mg/kg of acarbose were given orally to HF-H2O2 treated rats, while combination of acarbose and Oleuropein (50mg/kg. B.W) were given orally to (HFr-H2O2) treated rats in group T3. Blood samples were taken at zero time and after two months of the experiment for measuring some parameters related to glycemic index and antioxidant status. The results declared an elevation in the glycemic index (insulin and glucose concentrations and insulin resistance (IR)) and malondialdehyde (MDA) and depression in glutathione (GSH) concentrations in T1 group at the end of experiment comparing to other treated groups. Antioxidant status and glycemic index were restored after acarbose or combination of acarbose and Oleuropein treatment characterized by significant depression of serum glucose, insulin concentrations and IR, and alleviation of oxidative stress clarified by depression of serum MDA with elevation in serum GSH concentration in groups T2 and T3. On conclusion, the current study documented the oxidative and hyperglycemic effect of fructose and H2O2 that can be ameliorating by oral administration of acarbose. Besides, combination of OLUE supplement with acarbose possessed additive effects. ","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85904329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.36326/kjvs/2022/v13i29771
Zainab Al-Bermani, Ahmed H. AlـDabhawi
The present study was conducted in the Al-Najaf slaughterhouse, during the period from November 2020 to March 2021, were collected 200 specimens of infected liver and lungs of sheep and cattle. The objective of the study is to investigate the number of hydatid cyst infections in cattle and sheep to investigate the macroscopic and microscopic characteristics, number and size of cysts in each lung and liver, comparison between the thickness of cysts wall in the liver of sheep and cattle infested with echinococcosis. The results of the macroscopic study showed the total number of cysts found in the liver of slaughtered sheep was 673 in different size groups while in the lung of slaughtered sheep, the total number of cysts was 216 cysts in different size groups. The examination of the lung of infected cattle during the period of our study revered no cystic lesions in the study while the total number of cysts found in the liver of slaughtered cattle was 158 in different group sizes, almost 50 % of the size of the hydatid cyst in the sheep liver is between 1-3 cm, while in cattle is between 3-5 cm. The microscopic investigation of the liver and lung specimens stained with hematoxylin and eosin stain and another stain was used in this study to evaluate the fibrous tissue proliferation via Masson's trichrome stain. showed there were features of chronic inflammation in hepatic tissue of infested sheep and cattle by cystic echinococcosis represented by marginal fibrous tissue layer surrounding the hydatid cyst, infiltration of mononuclear cells, eosinophils, neutrophils, macrophages, and fibrocytes. The main conclusions of the study revealed that there were significant differences between the thickness of germinativum, laminated and adventitial layers of hydatid cysts in different size groups, and no hydatid cysts were recognized in the lung of slaughtered cattle during the study period.
{"title":"Gross and histopathological changes in liver and lung of cattle and sheep infected with hydatid cyst","authors":"Zainab Al-Bermani, Ahmed H. AlـDabhawi","doi":"10.36326/kjvs/2022/v13i29771","DOIUrl":"https://doi.org/10.36326/kjvs/2022/v13i29771","url":null,"abstract":"The present study was conducted in the Al-Najaf slaughterhouse, during the period from November 2020 to March 2021, were collected 200 specimens of infected liver and lungs of sheep and cattle. The objective of the study is to investigate the number of hydatid cyst infections in cattle and sheep to investigate the macroscopic and microscopic characteristics, number and size of cysts in each lung and liver, comparison between the thickness of cysts wall in the liver of sheep and cattle infested with echinococcosis. The results of the macroscopic study showed the total number of cysts found in the liver of slaughtered sheep was 673 in different size groups while in the lung of slaughtered sheep, the total number of cysts was 216 cysts in different size groups. The examination of the lung of infected cattle during the period of our study revered no cystic lesions in the study while the total number of cysts found in the liver of slaughtered cattle was 158 in different group sizes, almost 50 % of the size of the hydatid cyst in the sheep liver is between 1-3 cm, while in cattle is between 3-5 cm. The microscopic investigation of the liver and lung specimens stained with hematoxylin and eosin stain and another stain was used in this study to evaluate the fibrous tissue proliferation via Masson's trichrome stain. showed there were features of chronic inflammation in hepatic tissue of infested sheep and cattle by cystic echinococcosis represented by marginal fibrous tissue layer surrounding the hydatid cyst, infiltration of mononuclear cells, eosinophils, neutrophils, macrophages, and fibrocytes. The main conclusions of the study revealed that there were significant differences between the thickness of germinativum, laminated and adventitial layers of hydatid cysts in different size groups, and no hydatid cysts were recognized in the lung of slaughtered cattle during the study period.\u0000 ","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73989190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.36326/kjvs/2022/v13i29772
A. Abdulameer, Nazih Wayes Zaid
This study was designed in order to investigate and determine the effect of black current (Prunus cerasus) extract on semen membrane and acrosome integrity of the rams. Twelve mature healthy rams were used in this study aged between 2-3 years, kept in the animal farm of the College of Veterinary Medicine, Al-Kufa University. Semen ejaculates was collected using electro-ejaculator methods once weekly a total of 36 ejaculates were collected among the period of the study. The black current (Prunus cerasus) extract was prepared by using maceration and added to the diluted semen in five doses groups (0.25 gm/ml as G1, 0.5 gm/ml as G2, 1 gm/ml as G3, 2 gm/ml as G4, 4 gm/ml as G5) and the positive control group left without any addition. The treatment samples were evaluated under cooling for five consecutive days, the membrane integrity test was evaluated using hypo-osmotic solution and acrosome integrity was analysis using semen smear stained with eosin–nigrosin stain. The result showed that high concentration of aqueous plant extract give negative result as listed in G3, G4 and G5 in the all preservation days. As found in acrosome integrity at the 5thday of incubation showed decreased at highly significantly sequentially. We conclude that the G1 and G2 of black current extract (Prunus cerasus) should be used in chilling process as a part of artificial insemination in sheep due to its protective effect of the membrane and acrosome integrity.
{"title":"Sperm Membrane and Acrosomal Integrity Affected by using Black Currant","authors":"A. Abdulameer, Nazih Wayes Zaid","doi":"10.36326/kjvs/2022/v13i29772","DOIUrl":"https://doi.org/10.36326/kjvs/2022/v13i29772","url":null,"abstract":"This study was designed in order to investigate and determine the effect of black current (Prunus cerasus) extract on semen membrane and acrosome integrity of the rams. Twelve mature healthy rams were used in this study aged between 2-3 years, kept in the animal farm of the College of Veterinary Medicine, Al-Kufa University. Semen ejaculates was collected using electro-ejaculator methods once weekly a total of 36 ejaculates were collected among the period of the study. The black current (Prunus cerasus) extract was prepared by using maceration and added to the diluted semen in five doses groups (0.25 gm/ml as G1, 0.5 gm/ml as G2, 1 gm/ml as G3, 2 gm/ml as G4, 4 gm/ml as G5) and the positive control group left without any addition. The treatment samples were evaluated under cooling for five consecutive days, the membrane integrity test was evaluated using hypo-osmotic solution and acrosome integrity was analysis using semen smear stained with eosin–nigrosin stain. The result showed that high concentration of aqueous plant extract give negative result as listed in G3, G4 and G5 in the all preservation days. As found in acrosome integrity at the 5thday of incubation showed decreased at highly significantly sequentially. We conclude that the G1 and G2 of black current extract (Prunus cerasus) should be used in chilling process as a part of artificial insemination in sheep due to its protective effect of the membrane and acrosome integrity. ","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90527066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-13DOI: 10.36330/kmj.v18i2.10386
Mohammed Akeel Yasseen, Mohammed Alobaidi
Background: Lumbar disc herniation is frequently-occurring and the most common spine-related disease in orthopedic surgery. However, nearly more than 50% of affected persons usually respond to conservative treatment. Furthermore, there is another group of patients who are suffering from incapacitating low back pain and sciatica although they have been treated for more than 6 weeks or who are suffering from early or progressive neurological impairment that required another approach far from the conservative treatments. Aim of the Study: The present study is designed to unveil the most reliable procedure which should be most adopted for single level lumbar disc herniation in Iraqi patients. Patients and Methods: A total of 40 patients who were suffering from back pain radiated to the lower limb were included in the present investigation. Out of them, 20 patients underwent open discectomy and the other 20 patients underwent tubular discectomy. Results: 1- At the 10th day of postoperatively assessment, an obvious statistically significant decrease in the mean total Oswestry low back pain disability score was recorded in micro-tubular discectomy compared with the open discectomy ( P<0.001). 2- At the 6th month of postoperatively, the mean total Oswestry low back pain disability score was increased in both groups; nonetheless, there has still been a decrease in the micro-tubular discectomy group in comparison with that of open discectomy group (P<0.001).
{"title":"A Comparison of Tubular Minimal Invasive Surgery and Conventional Surgery in The Treatment of Patients Suffering from Single Level Lumber Disc Herniation (Short Term Follow Up)","authors":"Mohammed Akeel Yasseen, Mohammed Alobaidi","doi":"10.36330/kmj.v18i2.10386","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.10386","url":null,"abstract":"Background: Lumbar disc herniation is frequently-occurring and the most common spine-related disease in orthopedic surgery. However, nearly more than 50% of affected persons usually respond to conservative treatment. Furthermore, there is another group of patients who are suffering from incapacitating low back pain and sciatica although they have been treated for more than 6 weeks or who are suffering from early or progressive neurological impairment that required another approach far from the conservative treatments.\u0000Aim of the Study: The present study is designed to unveil the most reliable procedure which should be most adopted for single level lumbar disc herniation in Iraqi patients.\u0000Patients and Methods: A total of 40 patients who were suffering from back pain radiated to the lower limb were included in the present investigation. Out of them, 20 patients underwent open discectomy and the other 20 patients underwent tubular discectomy.\u0000Results:\u00001- At the 10th day of postoperatively assessment, an obvious statistically significant decrease in the mean total Oswestry low back pain disability score was recorded in micro-tubular discectomy compared with the open discectomy ( P<0.001).\u00002- At the 6th month of postoperatively, the mean total Oswestry low back pain disability score was increased in both groups; nonetheless, there has still been a decrease in the micro-tubular discectomy group in comparison with that of open discectomy group (P<0.001).","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81640978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-13DOI: 10.36330/kmj.v18i2.10385
Mona Jasim Mohammed, Ahmad Alzubaidi
Background: Endoscopic skull base surgery is a well-established technique for the treatment of skull base pathologies. Once the resection is complete, reconstruction of the sellar floor is performed. Fat and fascia lata are used in an underlay fashion and then the dural sealant is placed over the repair. Aim of the study: The study aims to assess the reconstruction of skull base defects after trans sphenoidal endoscopic surgery. Patients and Methods: A total of 15 patients, 11 females & 4 males, were exposed to a cross-sectional study. The age of the participant ranged between 13 to 73 years old. The present work was carried out at Al-Hayat Private Hospital for the period starting from October 2017 to October 2021. All patients were followed up for at least 6 months' duration to assess the final outcome of the surgical operation. All the patients were informed of the aim of the study and they willingly agreed to participate; written consents were obtained from all of them. Results: No CSF leak happened postoperatively in the patients. In spite of the small group of patients in the study, it can be concluded that the way of reconstructing the skull base has been effective
{"title":"Evaluating Skull base Defect Reconstruction after Endoscopic Transsphenoidal Approach among Iraqi Patients","authors":"Mona Jasim Mohammed, Ahmad Alzubaidi","doi":"10.36330/kmj.v18i2.10385","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.10385","url":null,"abstract":"Background: Endoscopic skull base surgery is a well-established technique for the treatment of skull base pathologies. Once the resection is complete, reconstruction of the sellar floor is performed. Fat and fascia lata are used in an underlay fashion and then the dural sealant is placed over the repair.\u0000Aim of the study: The study aims to assess the reconstruction of skull base defects after trans sphenoidal endoscopic surgery.\u0000Patients and Methods: A total of 15 patients, 11 females & 4 males, were exposed to a cross-sectional study. The age of the participant ranged between 13 to 73 years old. The present work was carried out at Al-Hayat Private Hospital for the period starting from October 2017 to October 2021. All patients were followed up for at least 6 months' duration to assess the final outcome of the surgical operation. All the patients were informed of the aim of the study and they willingly agreed to participate; written consents were obtained from all of them. \u0000Results: No CSF leak happened postoperatively in the patients. In spite of the small group of patients in the study, it can be concluded that the way of reconstructing the skull base has been effective","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80006184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that may affect the joints, skin, kidneys, lungs, nervous system, and serous membranes and/or other organs. Lymphadenopathy is characterized by changes in the characteristics and size of the lymph nodes. It results from reticuloendothelial proliferation secondary to inflammation, infection, or malignancies. Lymphadenopathy is common in SLE. It has been reported that lymph node enlargement is observed in 25-67% of SLE patients. We reported this thirty-three-year patient with presented with lymph node enlargement in cervical, axillary, and inguinal, joint pain, renal involvement and respiratory involvement diagnosed as Systemic lupus erythematosus according to ACR/EULAR criteria immunological and clinical domain SLICC (systemic lupus international collaborating clinics. In conclusion, lymphadenopathy is a manifestation in SLE. As illustrated by the case presented here, it can precede the diagnosis of SLE by many years; It is possible that the factors that induce lymph node proliferation are also responsible for the development of autoantibodies.
{"title":"Systemic Lupus Erythematosus with Initial Manifestation as Enlargement in Cervical, Axillary and Inguinal Lymphnodes: A Case Report","authors":"Aryan M Jalal, Niaz J. Al-Barzinji, S. Aref","doi":"10.36330/kmj.v18i2.9769","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.9769","url":null,"abstract":"Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that may affect the joints, skin, kidneys, lungs, nervous system, and serous membranes and/or other organs. Lymphadenopathy is characterized by changes in the characteristics and size of the lymph nodes. It results from reticuloendothelial proliferation secondary to inflammation, infection, or malignancies. Lymphadenopathy is common in SLE. It has been reported that lymph node enlargement is observed in 25-67% of SLE patients. We reported this thirty-three-year patient with presented with lymph node enlargement in cervical, axillary, and inguinal, joint pain, renal involvement and respiratory involvement diagnosed as Systemic lupus erythematosus according to ACR/EULAR criteria immunological and clinical domain SLICC (systemic lupus international collaborating clinics. \u0000In conclusion, lymphadenopathy is a manifestation in SLE. As illustrated by the case presented here, it can precede the diagnosis of SLE by many years; It is possible that the factors that induce lymph node proliferation are also responsible for the development of autoantibodies.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91112349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sanjad-Sakati syndrome is an inherited autosomal recessive disorder that presents primarily in the Arab countries, with its real prevalence not well established. It is a combination of specific facial dysmorphology, failure to thrive, hypoparathyroidism, and variable mental disability which is an unfortunately incurable disease with fatal outcomes.
{"title":"Sanjad-Sakati Syndrome in Al Najaf Governorate","authors":"Mahir Mohammed Ali Altaher","doi":"10.36330/kmj.v18i2.3685","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.3685","url":null,"abstract":"Sanjad-Sakati syndrome is an inherited autosomal recessive disorder that presents primarily in the Arab countries, with its real prevalence not well established. It is a combination of specific facial dysmorphology, failure to thrive, hypoparathyroidism, and variable mental disability which is an unfortunately incurable disease with fatal outcomes. ","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76651648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Autism Spectrum Disorder (ASD) is a combination of complex neurodevelopment disabilities. Early resting-state EEG investigations of autism failed to identify consistent patterns of atypical neural activity. The evidence for the U-shaped profile of electrophysiological power alterations in ASD is primarily supportive, but a more hypothesis-driven effort is needed to confirm and validate it. Aim of study: The primary objective of the present study was to investigate the resting-state QEEG neuro-biomarkers by amplitude analysis as a diagnostic tool for autistic children, compared with a normative group while recording qEEG during an eyes-open condition. Patients and Methods: After excluding those with less than one-minute artifact-free EEG data or too many artifacts, the final participants were (N = 34) autistic children. The age range was 2-11 years (mean age 6.235 ± SD 2.7198 years), including 30 males (mean age 6.1667 ± SD 2.730 years) and four females (mean age 6.75 ± SD 2.986 years). For the qEEG recording, BrainMaster Discovery 20 module and BrainAvatar 4.0 Discovery (Acquisition software) were used. Results: After calculating and analyzing all the QEEG data, the findings were categorized and confirmed the U-shaped power profile as an autism signature and as a diagnostic sign, characterized by excessive absolute power in low-frequencies (delta, theta) and high-frequencies bands (beta, hiBeta) and reduced absolute-power in a midrange frequency band (alpha). Conclusions: Recent literature and our findings have shown that ASD individuals have disturbances of neural connectivity. Neurofeedback (NFB) treatment seems to be an excellent approach to regulating such disorders when using QEEG neuro-biomarkers as a part of treatment planning.
{"title":"Resting-state QEEG Neuro-Biomarkers for Diagnosis and Treatment Planning of Autism Spectrum Disorders","authors":"A. Al-Salihy","doi":"10.36330/kmj.v18i2.3639","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.3639","url":null,"abstract":"Background: Autism Spectrum Disorder (ASD) is a combination of complex neurodevelopment disabilities. Early resting-state EEG investigations of autism failed to identify consistent patterns of atypical neural activity. The evidence for the U-shaped profile of electrophysiological power alterations in ASD is primarily supportive, but a more hypothesis-driven effort is needed to confirm and validate it.\u0000Aim of study: The primary objective of the present study was to investigate the resting-state QEEG neuro-biomarkers by amplitude analysis as a diagnostic tool for autistic children, compared with a normative group while recording qEEG during an eyes-open condition.\u0000Patients and Methods: After excluding those with less than one-minute artifact-free EEG data or too many artifacts, the final participants were (N = 34) autistic children. The age range was 2-11 years (mean age 6.235 ± SD 2.7198 years), including 30 males (mean age 6.1667 ± SD 2.730 years) and four females (mean age 6.75 ± SD 2.986 years). For the qEEG recording, BrainMaster Discovery 20 module and BrainAvatar 4.0 Discovery (Acquisition software) were used.\u0000Results: After calculating and analyzing all the QEEG data, the findings were categorized and confirmed the U-shaped power profile as an autism signature and as a diagnostic sign, characterized by excessive absolute power in low-frequencies (delta, theta) and high-frequencies bands (beta, hiBeta) and reduced absolute-power in a midrange frequency band (alpha).\u0000Conclusions: Recent literature and our findings have shown that ASD individuals have disturbances of neural connectivity. Neurofeedback (NFB) treatment seems to be an excellent approach to regulating such disorders when using QEEG neuro-biomarkers as a part of treatment planning.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89243562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We are herein reporting two female siblings with childhood-onset Systemic Lupus Erythematosus (SLE). The children were diagnosed as having SLE in reverse birth order at ages 2 and 6 years. Younger sister's initial symptoms were serositis, proteinuria, and hemolytic anemia with laboratory findings of hypocomplementemia and positive ANA/anti-dsDNA antibody. After 18 months, the older sister presented with high-grade fever, arthralgia proteinuria, oral mucous ulcer, butterfly rash, and positive ANA/anti-dsDNA antibody.
{"title":"Two Sisters were Diagnosed with Childhood Systemic Lupus Erythematous","authors":"A. Nasrawi, Heba Yihia Al Sunbly","doi":"10.36330/kmj.v18i2.3671","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.3671","url":null,"abstract":"We are herein reporting two female siblings with childhood-onset Systemic Lupus Erythematosus (SLE). The children were diagnosed as having SLE in reverse birth order at ages 2 and 6 years. Younger sister's initial symptoms were serositis, proteinuria, and hemolytic anemia with laboratory findings of hypocomplementemia and positive ANA/anti-dsDNA antibody. After 18 months, the older sister presented with high-grade fever, arthralgia proteinuria, oral mucous ulcer, butterfly rash, and positive ANA/anti-dsDNA antibody.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76103104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Selma Merza Hasan Al-Mousawi, Akram Faisal Alhuwaiz
Introduction: Inflammation associated with insertion of orthodontic miniscrews (OMS) may lead to their failure, therefore inhibition of microbial buildup is preferable. Chlorhexidine hexametaphosphate has offered persistent, slow release of active chlorhexidine over time, and hence a good anti-microbial agent. Aims of study: To prepare and characterize CHX-HMP antimicrobial nanoparticle for coating and characterization of the stainless steel and titanium orthodontic miniscrews. Materials and Methods: Suspension of 5 mM CHX-HMP nanoparticles were prepared. The formulated suspension was subjected to examination by AFM and FTIR. Sterilized miniscrews were immersed in the prepared suspension for half a minute, then inserted in deionized water for 10 seconds to eliminate any unbound material and then left to dry in air for at least 1 hour. The OMSs were examined by using SEM and FeSEM. Results: The AFM micrographs displayed that the characterization of nanoparticles expressed a relative homogeneity in terms of particle size and in their topographical distribution with the regular shaped particles being well aligned vertically with mean particles size 45.2 nm. FTIR showed the presence of C=O bond in chlorhexidine digluconate and its absence in the mixed nanoparticles indicate the replacement of gluconate by hexametaphosphate. SEM and FeSEM showed that all coated OMS (stainless steel and titanium) revealed nanoparticles of spherical shape with perfect homogenous distribution with no agglomeration meaning that the coating of OMS with the prepared colloidal suspension have a good dispersion of nanoparticles. Conclusion: OMS could be coated with antimicrobial CXH-HMP nanoparticles to assist reducing infection associated with the insertion of OMS.
简介:正畸微型支架(OMS)插入引起的炎症可能导致其失效，因此抑制微生物积聚是可取的。六偏磷酸氯己定具有持续缓慢释放活性氯己定的特性，因此是一种良好的抗菌剂。研究目的:制备CHX-HMP抗菌纳米颗粒，用于不锈钢和钛正畸微型支架的涂层和表征。材料与方法:制备5 mM CHX-HMP纳米颗粒悬浮液。采用原子力显微镜(AFM)和红外光谱(FTIR)对配制的悬浮液进行检测。将灭菌后的微型微生物浸泡在制备好的悬浮液中半分钟，然后将其插入去离子水中10秒以消除任何未结合的物质，然后将其放置在空气中干燥至少1小时。采用SEM和FeSEM对其进行了表征。结果:AFM显微图显示，纳米颗粒在粒径和地形分布方面表现出相对均匀性，规则形状的颗粒在垂直方向上排列良好，平均粒径为45.2 nm。傅里叶变换红外光谱显示，二光酸氯己定中存在C=O键，而混合纳米颗粒中不存在C=O键，表明葡萄糖酸盐被六偏磷酸取代。SEM和FeSEM结果表明，涂层后的OMS(不锈钢和钛)均呈现球形纳米颗粒，分布均匀，无团聚现象，说明制备的胶体悬浮液涂层具有良好的纳米颗粒分散性。结论:抗菌CXH-HMP纳米颗粒可包被OMS，有助于减少OMS插入引起的感染。
{"title":"Coating Orthodontic Miniscrew with Chlorhexidine Hexametaphosphate Nanoparticle (An in vitro-study)","authors":"Selma Merza Hasan Al-Mousawi, Akram Faisal Alhuwaiz","doi":"10.36330/kmj.v18i2.3681","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.3681","url":null,"abstract":"Introduction: Inflammation associated with insertion of orthodontic miniscrews (OMS) may lead to their failure, therefore inhibition of microbial buildup is preferable. Chlorhexidine hexametaphosphate has offered persistent, slow release of active chlorhexidine over time, and hence a good anti-microbial agent.\u0000Aims of study: To prepare and characterize CHX-HMP antimicrobial nanoparticle for coating and characterization of the stainless steel and titanium orthodontic miniscrews.\u0000Materials and Methods: Suspension of 5 mM CHX-HMP nanoparticles were prepared. The formulated suspension was subjected to examination by AFM and FTIR. Sterilized miniscrews were immersed in the prepared suspension for half a minute, then inserted in deionized water for 10 seconds to eliminate any unbound material and then left to dry in air for at least 1 hour. The OMSs were examined by using SEM and FeSEM.\u0000Results: The AFM micrographs displayed that the characterization of nanoparticles expressed a relative homogeneity in terms of particle size and in their topographical distribution with the regular shaped particles being well aligned vertically with mean particles size 45.2 nm. FTIR showed the presence of C=O bond in chlorhexidine digluconate and its absence in the mixed nanoparticles indicate the replacement of gluconate by hexametaphosphate. SEM and FeSEM showed that all coated OMS (stainless steel and titanium) revealed nanoparticles of spherical shape with perfect homogenous distribution with no agglomeration meaning that the coating of OMS with the prepared colloidal suspension have a good dispersion of nanoparticles.\u0000Conclusion: OMS could be coated with antimicrobial CXH-HMP nanoparticles to assist reducing infection associated with the insertion of OMS.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87757838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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