首页 > 最新文献

Kufa Journal For Veterinary Medical Sciences最新文献

英文 中文
Prevalence of Complications in Laparoscopic Cholecystectomy in Extracting Gallbladder by Using Supra-Umbilical Port Versus Epigastric Port in Sulaimani Teaching Hospital: A Prospective Case Series Study 苏莱马尼教学医院腹腔镜胆囊切除术脐上孔与腹上孔胆囊摘除术并发症发生率的前瞻性病例系列研究
Pub Date : 2021-10-14 DOI: 10.36330/kmj.v18i2.3716
H. Ahmed, A. Rashid
Background: Depending on the surgeon's preference, different locations for trocar incision can be used to extract the gallbladder. Some studies are claiming that epigastric port is better for retrieval due to easiness for the surgeon as there is no need to change the position of the telescope and readjustment of the surgeon’s position. Other studies show the superiority of umbilical port in terms of pain.Setting: Sulaimani Teaching Hospital.Aims: The current work aims at evaluating the port site for gallbladder retrieval in LCin terms of time for extracting the specimen, frequency of port site pain, surgical site infection, and incisional hernia.Patients and methods: This is a prospective randomized study including 108 patients who underwent laparoscopic cholecystectomy. It was conducted in Sulaimani Teaching Hospital from October 1st, 2020, to September 30th, 2021. Patients were divided into two groups matched in gender and age: Group A: Gallbladder was extracted from the epigastric port while in Group B: Gallbladder was extracted from the supra-umbilical port.Results: A two comparable groups of patients matched in gender and age were recruited with a mean age of 41.2 + 11.04 years ranged 20-68 years. Overall, 52.78 % (n=57) were female and 47.22% (n=51) were male with F/M ratio of 1.11/1. The time of the LCfor [21±4 min] was more in group B [n= 42, 38.9%] patients in contra to group A[n=37, 34.3%] patients, while for [33±2 minutes] it was more in group A [n= 6, 5.6% ] patients. Retrieval of the almost all the excised gall bladder (n=54, 98.18% patients) via supraumbilical port needs less time (≤5 minutes) in comparison to epigastric port (n=40, 75.47% patients).Conclusion: Based on these findings the safety and ease of supra-umbilical port for extraction of gallbladder during LChas been better than that in using epigastric port. Furthermore, it has taken less operative time with less patients complained of pain or surgical site infection, abscess, and port site incisional hernia.
背景:根据术者的喜好,套管针切口的不同位置可用于胆囊的取出。有研究认为,由于不需要改变望远镜的位置和调整术者的体位,手术方便,因此上胃口更适合手术。其他研究表明,在疼痛方面,脐带端口的优势。地点:苏莱曼尼教学医院。目的:本研究旨在从标本提取时间、port site疼痛频率、手术部位感染频率和切口疝等方面对LCin胆囊切除术的port site进行评价。患者和方法:这是一项前瞻性随机研究,包括108例接受腹腔镜胆囊切除术的患者。于2020年10月1日至2021年9月30日在苏莱曼尼教学医院进行。患者根据性别和年龄分为两组:A组:从胃上孔取出胆囊;B组:从脐上孔取出胆囊。结果:招募了两组性别和年龄相匹配的患者,平均年龄为41.2 + 11.04岁,年龄范围为20-68岁。女性占52.78% (n=57),男性占47.22% (n=51), F/M比为1.11/1。B组[21±4 min]的lc时间多于A组[n= 42, 38.9%],而A组[33±2 min]的lc时间多于A组[n= 6, 5.6%]。几乎所有切除的胆囊(n=54, 98.18%)均经脐上口取出,所需时间(≤5分钟)比经胃上口取出(n=40, 75.47%)更短。结论:经脐上口取胆囊比经胃上口取胆囊更安全、方便。此外,它减少了手术时间,较少患者抱怨疼痛或手术部位感染,脓肿和端口切口疝。
{"title":"Prevalence of Complications in Laparoscopic Cholecystectomy in Extracting Gallbladder by Using Supra-Umbilical Port Versus Epigastric Port in Sulaimani Teaching Hospital: A Prospective Case Series Study","authors":"H. Ahmed, A. Rashid","doi":"10.36330/kmj.v18i2.3716","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.3716","url":null,"abstract":"Background: Depending on the surgeon's preference, different locations for trocar incision can be used to extract the gallbladder. Some studies are claiming that epigastric port is better for retrieval due to easiness for the surgeon as there is no need to change the position of the telescope and readjustment of the surgeon’s position. Other studies show the superiority of umbilical port in terms of pain.\u0000Setting: Sulaimani Teaching Hospital.\u0000Aims: The current work aims at evaluating the port site for gallbladder retrieval in LCin terms of time for extracting the specimen, frequency of port site pain, surgical site infection, and incisional hernia.\u0000Patients and methods: This is a prospective randomized study including 108 patients who underwent laparoscopic cholecystectomy. It was conducted in Sulaimani Teaching Hospital from October 1st, 2020, to September 30th, 2021. Patients were divided into two groups matched in gender and age: Group A: Gallbladder was extracted from the epigastric port while in Group B: Gallbladder was extracted from the supra-umbilical port.\u0000Results: A two comparable groups of patients matched in gender and age were recruited with a mean age of 41.2 + 11.04 years ranged 20-68 years. Overall, 52.78 % (n=57) were female and 47.22% (n=51) were male with F/M ratio of 1.11/1. The time of the LCfor [21±4 min] was more in group B [n= 42, 38.9%] patients in contra to group A[n=37, 34.3%] patients, while for [33±2 minutes] it was more in group A [n= 6, 5.6% ] patients. Retrieval of the almost all the excised gall bladder (n=54, 98.18% patients) via supraumbilical port needs less time (≤5 minutes) in comparison to epigastric port (n=40, 75.47% patients).\u0000Conclusion: Based on these findings the safety and ease of supra-umbilical port for extraction of gallbladder during LChas been better than that in using epigastric port. Furthermore, it has taken less operative time with less patients complained of pain or surgical site infection, abscess, and port site incisional hernia.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84670671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detecting Phenotypic and Genotypic of the Antibiotic Resistant Salmonella enterica Serotype Paratyphi Isolated from Blood Samples in Najaf Province /Iraq 伊拉克纳杰夫省耐药肠炎沙门氏菌血清型副伤寒的表型和基因型检测
Pub Date : 2021-10-14 DOI: 10.36330/kmj.v18i2.10292
Fadhil Hussain Nasir Al-Muhannak, Hashim Ali Abdualmeer Al-sherees, Ibrahim Abed Ali Abdul Sada, T. Mahmood, R. Obaid
Background & Objectives: Salmonella Paratyphi is a leading cause of human paratyphoid fever in developing countries, causing deaths in humans worldwide. There are several paths for catching paratyphoid fever, but the close contact between patients and healthy humans is so far the most frequent cause of human infections. No study is found about the antibiotic resistance (phenotypic and genetic) of S. Paratyphi isolated from patients in Al-Najaf Province/Iraq, to the researcher’s best knowledge. Hence, this study aimed to determine the prevalence of S. Paratyphi isolates from blood specimens and the antibiotic resistance determinants of them, as well as the genetic relationship among isolates.Methods and Results: Blood specimens from 1743 patients with suspected enteric fever were cultured for the identification of Salmonella enterica during the period from first April to the end of October 2017. 107 (6.14%) S. enterica isolates were recovered and only two (1.87%) of isolates were S. enterica serovar Paratyphi B. These two isolates (ST39 and ST89) were tested against 23 antibiotics using the disc diffusion method on Muller-Hinton agar and the genotypic antibiotic resistance determinants by PCR. ST39 isolate was sensitive to all antibiotics while ST89 isolate was resistant to only cefepime, piperacillin and tobramycin. ST39 isolate did not carry integrons (1 or 2) and any resistance determinants, while ST89 isolate carried integron class1 as well as blaTEM, blaCTX-M and aac(6')-lb genes.Conclusions: The findings of S. Paratyphi isolates with integron 1 and resistant antibiotic genes indicating public health risks.
背景与目的:副伤寒沙门氏菌是发展中国家人类副伤寒的主要病因,在世界范围内造成人类死亡。副伤寒有几种感染途径,但迄今为止,患者与健康人之间的密切接触是人类感染的最常见原因。据研究人员所知,尚未发现从伊拉克Al-Najaf省患者中分离出的副伤寒沙门氏菌的抗生素耐药性(表型和遗传)研究。因此,本研究旨在确定血液标本中副伤寒沙门氏菌分离株的流行率及其抗生素耐药性决定因素,以及分离株之间的遗传关系。方法与结果:对2017年4月1日至10月底1743例疑似肠热患者的血液标本进行肠沙门氏菌培养鉴定。采用Muller-Hinton琼脂盘扩散法检测ST39和ST89菌株对23种抗生素的耐药性,并采用PCR检测其基因型耐药性决定因素,共回收107株(6.14%)肠球菌,其中2株(1.87%)为肠球菌血清型副伤寒杆菌。ST39对所有抗菌药物均敏感,而ST89仅对头孢吡肟、哌拉西林和妥布霉素耐药。ST39分离物不携带整合子(1或2)和任何抗性决定因子,而ST89分离物携带整合子class1以及blaTEM、blaCTX-M和aac(6')-lb基因。结论:副伤寒沙门氏菌分离株携带整合子1和耐药基因提示公共卫生风险。
{"title":"Detecting Phenotypic and Genotypic of the Antibiotic Resistant Salmonella enterica Serotype Paratyphi Isolated from Blood Samples in Najaf Province /Iraq","authors":"Fadhil Hussain Nasir Al-Muhannak, Hashim Ali Abdualmeer Al-sherees, Ibrahim Abed Ali Abdul Sada, T. Mahmood, R. Obaid","doi":"10.36330/kmj.v18i2.10292","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.10292","url":null,"abstract":"Background & Objectives: Salmonella Paratyphi is a leading cause of human paratyphoid fever in developing countries, causing deaths in humans worldwide. There are several paths for catching paratyphoid fever, but the close contact between patients and healthy humans is so far the most frequent cause of human infections. No study is found about the antibiotic resistance (phenotypic and genetic) of S. Paratyphi isolated from patients in Al-Najaf Province/Iraq, to the researcher’s best knowledge. Hence, this study aimed to determine the prevalence of S. Paratyphi isolates from blood specimens and the antibiotic resistance determinants of them, as well as the genetic relationship among isolates.\u0000Methods and Results: Blood specimens from 1743 patients with suspected enteric fever were cultured for the identification of Salmonella enterica during the period from first April to the end of October 2017. 107 (6.14%) S. enterica isolates were recovered and only two (1.87%) of isolates were S. enterica serovar Paratyphi B. These two isolates (ST39 and ST89) were tested against 23 antibiotics using the disc diffusion method on Muller-Hinton agar and the genotypic antibiotic resistance determinants by PCR. ST39 isolate was sensitive to all antibiotics while ST89 isolate was resistant to only cefepime, piperacillin and tobramycin. ST39 isolate did not carry integrons (1 or 2) and any resistance determinants, while ST89 isolate carried integron class1 as well as blaTEM, blaCTX-M and aac(6')-lb genes.\u0000Conclusions: The findings of S. Paratyphi isolates with integron 1 and resistant antibiotic genes indicating public health risks.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79219074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Determinants of Depression among Women with Breast Cancer in Middle Euphrates Cancer Center in Najaf Province -Iraq 伊拉克纳杰夫省幼发拉底河中部癌症中心乳腺癌妇女抑郁患病率及决定因素
Pub Date : 2021-10-14 DOI: 10.36330/kmj.v18i2.9770
S. Alfadhul
Background: Breast cancer (BC) is the most prevalent cancer among women worldwide. The psychosocial consequences of illness among women with BC are so frequent that they result in depression and other psychological distress.Objectives: The present study aims to estimate the prevalence of depression among BC patients and to identify the potential determinants.                                                Patients & Methods: An analytic cross-sectional study of patients with BC was carried out throughout the period from January 2016 to July 2016 at the Middle Euphrates Cancer Center in Najaf Province-Iraq. Results: According to the results of BDI-ӀӀ questionnaire, 65 patients (37.1%) were screened as having depression and 110 patients (62.9%) were considered normal. The mean score for depression ± SD is equal to 13.60 ±8.78. The data analysis has found that 12.0%, 21.7%, and 3.4% of respondents had borderline, moderate depression, and severe depression, respectively while the binary logistic regression analysis has shown that cases with inadequate income (P= 0.010, OR =2.52, 95% C.I = 1.28-5.08), and lower educational attainment (P= 0.031, OR = 2.34, 95% C.I = 1.07-4.90) were more likely to have depression. Conclusion: it has been found that depression among women with BC is a considerable issue. Inadequate income and lower educational attainment can be independent risk factors for such a depression.
背景:乳腺癌(BC)是世界范围内最常见的女性癌症。患有BC的妇女疾病的社会心理后果是如此频繁,以至于导致抑郁和其他心理困扰。目的:本研究旨在估计BC患者中抑郁症的患病率,并确定潜在的决定因素。患者与方法:2016年1月至2016年7月,在伊拉克纳杰夫省幼发拉底河中部癌症中心对BC患者进行了一项分析性横断面研究。结果:根据BDI-ӀӀ问卷调查结果,65例(37.1%)患者被筛查为抑郁症,110例(62.9%)患者被认为正常。抑郁的平均得分±SD = 13.60±8.78。数据分析发现,12.0%、21.7%和3.4%的受访者分别患有边缘性、中度和重度抑郁症,而二元logistic回归分析显示,收入不足(P= 0.010, OR =2.52, 95% ci = 1.28 ~ 5.08)和受教育程度较低(P= 0.031, OR = 2.34, 95% ci = 1.07 ~ 4.90)的患者更易患抑郁症。结论:研究发现,女性BC患者的抑郁是一个相当大的问题。收入不足和受教育程度较低可能是这种抑郁症的独立风险因素。
{"title":"Prevalence and Determinants of Depression among Women with Breast Cancer in Middle Euphrates Cancer Center in Najaf Province -Iraq","authors":"S. Alfadhul","doi":"10.36330/kmj.v18i2.9770","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.9770","url":null,"abstract":"Background: Breast cancer (BC) is the most prevalent cancer among women worldwide. The psychosocial consequences of illness among women with BC are so frequent that they result in depression and other psychological distress.\u0000Objectives: The present study aims to estimate the prevalence of depression among BC patients and to identify the potential determinants.                                                \u0000Patients & Methods: An analytic cross-sectional study of patients with BC was carried out throughout the period from January 2016 to July 2016 at the Middle Euphrates Cancer Center in Najaf Province-Iraq. \u0000Results: According to the results of BDI-ӀӀ questionnaire, 65 patients (37.1%) were screened as having depression and 110 patients (62.9%) were considered normal. The mean score for depression ± SD is equal to 13.60 ±8.78. The data analysis has found that 12.0%, 21.7%, and 3.4% of respondents had borderline, moderate depression, and severe depression, respectively while the binary logistic regression analysis has shown that cases with inadequate income (P= 0.010, OR =2.52, 95% C.I = 1.28-5.08), and lower educational attainment (P= 0.031, OR = 2.34, 95% C.I = 1.07-4.90) were more likely to have depression. \u0000Conclusion: it has been found that depression among women with BC is a considerable issue. Inadequate income and lower educational attainment can be independent risk factors for such a depression.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73663861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Small Round Cell Tumors in Pediatric Age Group in the last 10 Years Registered in Al- Najaf Governorate 最近10年纳杰夫省儿童年龄组小圆细胞肿瘤的流行情况
Pub Date : 2021-10-14 DOI: 10.36330/kmj.v18i2.10314
Luma Alwaiely, Kaswer Musa Al-Turaihi
Malignant small round cell tumors (MSRCT) are referred to as tumors made up of malignant small round cells. The cells in this type of neoplasms are tiny, rounded, and largely undifferentiated. Ewing's sarcoma (ES), peripheral neuroectodermal tumor, rhabdomyosarcoma, non-Hodgkin lymphoma, retinoblastoma, neuroblastoma, hepatoblastoma, and nephroblastoma are a few of the more common ones. The aim of this study is to estimate the prevalence and types of pediatric small round cell tumors in Najaf Province/Iraq, over the 10 years period between 2010-2019.Method: This is a retrospective observational study. Cases were collected from pathology laboratories in As-Sadr Medical City and some private laboratories in Najaf over a 10 year-period extending from 2010 to 2019.Results: A 6366 pediatric surgical biopsy cases were reported during the study period and this represent 8.7% of all cases. Out of these cases, 108 cases with small round cell tumors (SRCT) have given a prevalence rate of 17 per 1000 pediatric cases and 1.5 per 1000 of total (73504) adult and pediatric cases during the same period. The mean age of these SRCT cases was 6.3± 1.6 (range: one month-19) years. The higher proportion of cases was reported in the age of 1-5 years, contributed for 43.5%. Male to female ratio is 59/108 vs. 49/108, respectively, the male to female ratio being at 1.2 to 1.0.Conclusions: The mean age of SRCTs cases was 6.3± 1.6, ranging from one month to 19 years. The higher proportion of SRCTs cases was reported in the age ranging from 1-5 years; with a ratio of males to females being 1.2 to 1.0.
恶性小圆细胞瘤(MSRCT)是由恶性小圆细胞组成的肿瘤。这种肿瘤的细胞很小,呈圆形,大部分未分化。尤文氏肉瘤(ES)、周围神经外胚层肿瘤、横纹肌肉瘤、非霍奇金淋巴瘤、视网膜母细胞瘤、神经母细胞瘤、肝母细胞瘤和肾母细胞瘤是比较常见的几种。本研究的目的是估计2010-2019年10年间伊拉克纳杰夫省儿童小圆细胞肿瘤的患病率和类型。方法:回顾性观察性研究。从2010年至2019年的10年期间,从萨德尔医疗城的病理实验室和纳杰夫的一些私人实验室收集病例。结果:在研究期间报告了6366例儿科手术活检病例,占所有病例的8.7%。在这些病例中,108例小圆细胞肿瘤(SRCT)在同一时期的患病率为每1000例儿童病例中有17例,每1000例(73504例)成人和儿童病例中有1.5例。这些SRCT病例的平均年龄为6.3±1.6岁(范围:1个月19岁)。其中以1 ~ 5岁发病比例最高,占43.5%。男女比例分别为59/108和49/108,男女比例为1.2比1.0。结论:srct病例的平均年龄为6.3±1.6岁,年龄范围为1个月至19岁。报告的srct病例比例较高的年龄范围为1-5岁;男女比例为1.2比1.0。
{"title":"Prevalence of Small Round Cell Tumors in Pediatric Age Group in the last 10 Years Registered in Al- Najaf Governorate","authors":"Luma Alwaiely, Kaswer Musa Al-Turaihi","doi":"10.36330/kmj.v18i2.10314","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.10314","url":null,"abstract":"Malignant small round cell tumors (MSRCT) are referred to as tumors made up of malignant small round cells. The cells in this type of neoplasms are tiny, rounded, and largely undifferentiated. Ewing's sarcoma (ES), peripheral neuroectodermal tumor, rhabdomyosarcoma, non-Hodgkin lymphoma, retinoblastoma, neuroblastoma, hepatoblastoma, and nephroblastoma are a few of the more common ones. The aim of this study is to estimate the prevalence and types of pediatric small round cell tumors in Najaf Province/Iraq, over the 10 years period between 2010-2019.\u0000Method: This is a retrospective observational study. Cases were collected from pathology laboratories in As-Sadr Medical City and some private laboratories in Najaf over a 10 year-period extending from 2010 to 2019.\u0000Results: A 6366 pediatric surgical biopsy cases were reported during the study period and this represent 8.7% of all cases. Out of these cases, 108 cases with small round cell tumors (SRCT) have given a prevalence rate of 17 per 1000 pediatric cases and 1.5 per 1000 of total (73504) adult and pediatric cases during the same period. The mean age of these SRCT cases was 6.3± 1.6 (range: one month-19) years. The higher proportion of cases was reported in the age of 1-5 years, contributed for 43.5%. Male to female ratio is 59/108 vs. 49/108, respectively, the male to female ratio being at 1.2 to 1.0.\u0000Conclusions: The mean age of SRCTs cases was 6.3± 1.6, ranging from one month to 19 years. The higher proportion of SRCTs cases was reported in the age ranging from 1-5 years; with a ratio of males to females being 1.2 to 1.0.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87445794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of General Anesthesia Induction Drugs on Cardiac Output of Patients in Azadi Teaching Hospital/Duhok/Iraq 阿扎迪教学医院/杜霍克/伊拉克全麻诱导药物对患者心输出量的影响
Pub Date : 2021-10-14 DOI: 10.36330/kmj.v18i2.10195
Faheema Mahmood Ali, Haidar nasser Mohammed
Background: Cardiac output can be decreased by many factors whose effects may be exaggerated during induction of anesthesia (which is already insulted to have negative effect on cardiac output) till the point of cardiac stand still.Aims: This study aims to answer the questions that “Is there any effect of general anesthesia induction agents on cardiac output? If there is any, which patient is affected more?”.The Study Design: It is a cross sectional study with convenient sampling procedure. According to the inclusion criteria,  it includes patients planning to perform surgical procedure under general anesthesia while it excludes patients who refused to participate in the study or their surgical procedures had been canceled for certain reasons.Method and Patients: The study targeted a population from Duhok province and its territories; 207 patients, were admitted to Cardiac Center Operation theatres from 12/9/2021 to 30/10/2021 and Azadi Teaching Hospital operation theatres from 2/11/2021 to 15/1/2022. The data were collected pre operatively after taking a verbal consent as age, sex, weight, chronic diseases and duration of chronic diseases. Foreword by using echocardiography machine pre and post general anesthesia induction ejection fraction would be obtained. All this information would put in previously designed excel form. This data had been analyzed by Microsoft Excel Worksheet and transferred to SPSS V. 23(IBM). Descriptive statistics (central tendency) and proportions of uni-variant variables were calculated. Paired t test for sample mean difference and ANOVA test for more than two group means were applied to test the mean differences. A P value of < 0.05 considered statistically significant.Results: For the age of patients the mean was 40 years with range 77 years, minimum 1 year, maximum 78 year and standard deviation 15.731 years, for weight the mean was 71kg with range 130 kg, minimum 7kg, maximum 137kg, and standard deviation17.210 kg, for pre general anesthesia induction anesthesia the mean was 0.6055 %with range 0.45%, minimum 0.35%, maximum 0.80%, and standard deviation 0.06587%, for post general anesthesia induction the mean was 0.5531% with range 0.54%, minimum 0.24%, maximum 0.78% and standard deviation 0.087485, for duration of chronic diseases out of 41 patients the mean was 1.47 years with range 26 years, maximum 26 years, and standard deviation 3.802 years fortunately 166(80%) of patients were without any chronic diseases.  The post induction ejection fraction significantly differs with the pre operation ejection fraction for (207) patients received anesthesia in Duhok hospitals during 2021. The average means difference was of 0.04499 (95% confidence interval, 0.04499, 0.05984.69). This difference is statistically significant at a ≤ .05 by the paired τ test (two-tailed).  In this study, patients underwent induction of anesthesia had an average of .05242 (standard deviation, .00377) change in ejection fraction.
背景:心输出量的减少可由许多因素引起,这些因素在麻醉诱导期间(已经被侮辱为对心输出量有负面影响)的作用可能被夸大,直到心脏停止。目的:本研究旨在回答“全麻诱导剂对心输出量是否有影响?”如果有,哪个病人受影响更大?”研究设计:这是一个具有方便抽样程序的横断面研究。根据纳入标准,包括计划在全身麻醉下进行手术的患者,不包括拒绝参加研究或因某种原因取消手术的患者。方法和患者:研究对象是来自杜胡克省及其地区的人群;207例患者于2021年9月12日至2021年10月30日在心脏中心手术室就诊,于2021年11月2日至2022年1月15日在阿扎迪教学医院手术室就诊。术前口头同意年龄、性别、体重、慢性疾病、慢性疾病持续时间等资料。前言采用超声心动图法测定全麻前后诱导射血分数。所有这些信息都将放在先前设计的excel表格中。这些数据已通过Microsoft Excel Worksheet进行分析,并转移到SPSS V. 23(IBM)中。计算描述性统计(集中趋势)和单变量的比例。样本均数差异采用配对t检验,两组以上均数差异采用方差分析检验。P值< 0.05认为有统计学意义。结果:患者年龄平均为40岁,范围为77岁,最小1年,最大78年,标准差为15.731年;体重平均为71kg,范围为130 kg,最小7kg,最大137kg,标准差为17.210 kg;全麻前诱导麻醉平均为0.6055%,范围为0.45%,最小0.35%,最大0.80%,标准差为0.06587%;全麻后诱导麻醉平均为0.5531%,范围为0.54%,最小0.24%;41例患者慢性疾病持续时间平均1.47年,范围26年,最长26年,标准差3.802年,所幸166例(80%)患者无任何慢性疾病。2021年在Duhok医院接受麻醉的207例患者的诱导后射血分数与术前射血分数有显著差异。平均差值为0.04499(95%可信区间为0.04499,0.05984.69)。通过配对τ检验(双尾),该差异在a≤0.05时具有统计学意义。在本研究中,接受麻醉诱导的患者射血分数平均变化为0.05242(标准差为0.00377)。
{"title":"The Effect of General Anesthesia Induction Drugs on Cardiac Output of Patients in Azadi Teaching Hospital/Duhok/Iraq","authors":"Faheema Mahmood Ali, Haidar nasser Mohammed","doi":"10.36330/kmj.v18i2.10195","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.10195","url":null,"abstract":"Background: Cardiac output can be decreased by many factors whose effects may be exaggerated during induction of anesthesia (which is already insulted to have negative effect on cardiac output) till the point of cardiac stand still.\u0000Aims: This study aims to answer the questions that “Is there any effect of general anesthesia induction agents on cardiac output? If there is any, which patient is affected more?”.\u0000The Study Design: It is a cross sectional study with convenient sampling procedure. According to the inclusion criteria,  it includes patients planning to perform surgical procedure under general anesthesia while it excludes patients who refused to participate in the study or their surgical procedures had been canceled for certain reasons.\u0000Method and Patients: The study targeted a population from Duhok province and its territories; 207 patients, were admitted to Cardiac Center Operation theatres from 12/9/2021 to 30/10/2021 and Azadi Teaching Hospital operation theatres from 2/11/2021 to 15/1/2022. The data were collected pre operatively after taking a verbal consent as age, sex, weight, chronic diseases and duration of chronic diseases. Foreword by using echocardiography machine pre and post general anesthesia induction ejection fraction would be obtained. All this information would put in previously designed excel form. This data had been analyzed by Microsoft Excel Worksheet and transferred to SPSS V. 23(IBM). Descriptive statistics (central tendency) and proportions of uni-variant variables were calculated. Paired t test for sample mean difference and ANOVA test for more than two group means were applied to test the mean differences. A P value of < 0.05 considered statistically significant.\u0000Results: For the age of patients the mean was 40 years with range 77 years, minimum 1 year, maximum 78 year and standard deviation 15.731 years, for weight the mean was 71kg with range 130 kg, minimum 7kg, maximum 137kg, and standard deviation17.210 kg, for pre general anesthesia induction anesthesia the mean was 0.6055 %with range 0.45%, minimum 0.35%, maximum 0.80%, and standard deviation 0.06587%, for post general anesthesia induction the mean was 0.5531% with range 0.54%, minimum 0.24%, maximum 0.78% and standard deviation 0.087485, for duration of chronic diseases out of 41 patients the mean was 1.47 years with range 26 years, maximum 26 years, and standard deviation 3.802 years fortunately 166(80%) of patients were without any chronic diseases.  The post induction ejection fraction significantly differs with the pre operation ejection fraction for (207) patients received anesthesia in Duhok hospitals during 2021. The average means difference was of 0.04499 (95% confidence interval, 0.04499, 0.05984.69). This difference is statistically significant at a ≤ .05 by the paired τ test (two-tailed).  In this study, patients underwent induction of anesthesia had an average of .05242 (standard deviation, .00377) change in ejection fraction.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78113040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship between Knowledge and Practice in Clinical Breast Examination among Women in Baghdad, Iraq 伊拉克巴格达妇女临床乳腺检查知识与实践的关系
Pub Date : 2021-10-14 DOI: 10.36330/kmj.v18i2.10295
Taqi Mohammed Jwad Taher, S. Alfadhul, Zainab Abbas Hassooni, Luma Hikmat Al-Bayati, Ban Atta Najman, Iman kadhim Ajlan, Baraa Abdulsalam Hraiga, Alyaa Razzaq Abed, Roaa M. H. Shoker, Thaer Hashim AbdulMuttaleb, Gasik Aqeele
Aim: This study aims to determine both the level  of knowledge, attitude, and practice  in clinical breast examination in women and the relationship between knowledge and practice.Data collection was performed within a three-month period starting from February 2019 on. Subjects and Method: A cross-sectional analytical study included 657 non-randomly selected women visiting primary health care centers in Baghdad city with an average of age between (20-59) years old. Results: Only 51.8% ever heard of clinical breast examination. The mean knowledge score for clinical breast examination was (51.2±44). Only 5.5% of women performed regular clinical breast examinations. Participants who adequately practice clinical breast examination had a statistically significance higher mean score of  knowledge than those without adequate clinical breast examination (100 vs 44.2), (P<0.001).Conclusion: The study has concluded that practices of clinical breast examination were inadequate in the majority of participants and need to be improved by educational programs.
目的:本研究旨在了解女性临床乳腺检查的知识、态度和实践水平,以及知识与实践之间的关系。数据收集在2019年2月起的三个月内进行。研究对象和方法:一项横断面分析研究包括657名非随机选择的访问巴格达市初级卫生保健中心的妇女,平均年龄在(20-59)岁之间。结果:仅有51.8%的人听说过临床乳腺检查。临床乳腺检查知识平均得分为(51.2±44)分。只有5.5%的妇女定期进行临床乳房检查。充分进行临床乳房检查的参与者比没有进行临床乳房检查的参与者的平均知识得分高(100比44.2),(P<0.001)。结论:该研究得出结论,大多数参与者的临床乳房检查实践不足,需要通过教育计划加以改进。
{"title":"The Relationship between Knowledge and Practice in Clinical Breast Examination among Women in Baghdad, Iraq","authors":"Taqi Mohammed Jwad Taher, S. Alfadhul, Zainab Abbas Hassooni, Luma Hikmat Al-Bayati, Ban Atta Najman, Iman kadhim Ajlan, Baraa Abdulsalam Hraiga, Alyaa Razzaq Abed, Roaa M. H. Shoker, Thaer Hashim AbdulMuttaleb, Gasik Aqeele","doi":"10.36330/kmj.v18i2.10295","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.10295","url":null,"abstract":"Aim: This study aims to determine both the level  of knowledge, attitude, and practice  in clinical breast examination in women and the relationship between knowledge and practice.Data collection was performed within a three-month period starting from February 2019 on. \u0000Subjects and Method: A cross-sectional analytical study included 657 non-randomly selected women visiting primary health care centers in Baghdad city with an average of age between (20-59) years old. \u0000Results: Only 51.8% ever heard of clinical breast examination. The mean knowledge score for clinical breast examination was (51.2±44). Only 5.5% of women performed regular clinical breast examinations. Participants who adequately practice clinical breast examination had a statistically significance higher mean score of  knowledge than those without adequate clinical breast examination (100 vs 44.2), (P<0.001).\u0000Conclusion: The study has concluded that practices of clinical breast examination were inadequate in the majority of participants and need to be improved by educational programs.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86583364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total Superficial Parotidectomy: Pros and Cons 腮腺浅表性全切除术:利弊
Pub Date : 2021-10-14 DOI: 10.36330/kmj.v18i2.10288
Mohemmed Habeeb SafeAllah, Baseem Natheer Abdulhadi, Ahmad Naeem Mahdi, Ahmed Fadhel Al-Quisi
Background: Total superficial parotidectomy is the most commonly used approach in excising the tumors that affect the superficial lobe of the parotid gland, whether they're benign or malignant.The aim of the study is to evaluate the benefits and drawbacks of total superficial parotidectomy for parotid gland tumors within five years of follow-up.Patients and methods: Nineteen patients with lateral facial swelling affecting the parotid region were included in this study. All of them operated under general anesthesia with oral endotracheal intubation, where Modified Blair Incision (lazy S incision) was utilized in all cases.Anterograde dissection with facial nerve identification was accomplished with total superficial parotidectomy.Results:  Fifteen patients had benign parotid tumors, and only four patients had well-differentiated mucoepidermoid carcinoma.Skin necrosis of the distal tip of the postauricular flap was the most commonly observed postoperative complication, it occurred in five patients; facial nerve weakness was observed in the another three patients.Conclusions: total superficial parotidectomy is an efficient, safe technique for benign and malignant tumors affecting the superficial lobe of the parotid gland with minimum postoperative complications.
背景:腮腺浅表全切除术是切除影响腮腺浅叶的肿瘤最常用的方法,无论其为良性还是恶性。本研究的目的是在随访5年内评估腮腺肿瘤全浅表腮腺切除术的利弊。患者和方法:本研究纳入了19例影响腮腺区域的面部外侧肿胀患者。所有病例均在全身麻醉下经口气管插管手术,所有病例均采用改良Blair切口(懒S切口)。顺行解剖与面神经识别是通过腮腺全浅表切除术完成的。结果:良性腮腺肿瘤15例,分化良好的粘液表皮样癌4例。术后最常见的并发症是耳后皮瓣远端皮肤坏死,发生5例;另外3例患者出现面神经无力。结论:腮腺浅表全切除术是治疗腮腺浅表良恶性肿瘤有效、安全、术后并发症少的手术方法。
{"title":"Total Superficial Parotidectomy: Pros and Cons","authors":"Mohemmed Habeeb SafeAllah, Baseem Natheer Abdulhadi, Ahmad Naeem Mahdi, Ahmed Fadhel Al-Quisi","doi":"10.36330/kmj.v18i2.10288","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.10288","url":null,"abstract":"Background: Total superficial parotidectomy is the most commonly used approach in excising the tumors that affect the superficial lobe of the parotid gland, whether they're benign or malignant.\u0000The aim of the study is to evaluate the benefits and drawbacks of total superficial parotidectomy for parotid gland tumors within five years of follow-up.\u0000Patients and methods: Nineteen patients with lateral facial swelling affecting the parotid region were included in this study. All of them operated under general anesthesia with oral endotracheal intubation, where Modified Blair Incision (lazy S incision) was utilized in all cases.\u0000Anterograde dissection with facial nerve identification was accomplished with total superficial parotidectomy.\u0000Results:  Fifteen patients had benign parotid tumors, and only four patients had well-differentiated mucoepidermoid carcinoma.\u0000Skin necrosis of the distal tip of the postauricular flap was the most commonly observed postoperative complication, it occurred in five patients; facial nerve weakness was observed in the another three patients.\u0000Conclusions: total superficial parotidectomy is an efficient, safe technique for benign and malignant tumors affecting the superficial lobe of the parotid gland with minimum postoperative complications.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88214481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of Buffalo Herd’s Diseases-Brucellosis, Toxoplasmosis, Foot and Mouth Disease- in Some Villages of Baghdad 巴格达一些村庄水牛群病——布鲁氏菌病、弓形虫病、口蹄疫的调查
Pub Date : 2021-06-30 DOI: 10.36326/kjvs/2021/v12i13224
Dr. Nadia Jasim Sudani, Dr. Ameerah Hussein, Qader, Dr. Hudhaifa Abdul, Mahdi Hadi, Dr. Luma Youssef, Dr. Salma Talib, Dr. Ibtisam Jasim, Sodani Dr. Ahmed, Mounir, Dr. Jabbar Khalaf, Dr. Kalaman Majid, Dr. Ahmed Fadel, Dr. Saeed Ibrahim, Qusay, Dr. Adnan Ibrahim Salem, دمحأ, فلخ, .د رابج, نملك, .د, ميهاربأ, ناندع.د, .د ديعس
This study is to investigate Brucellosis, Toxoplasmosis and Foot and Mouth disease of buffalo herds in Baghdad villages. 114 samples (serum) were collected, including 22 for calves less than 6 months and 92 samples of females aged between three to seven years, the samples were collected by staff of Baghdad Veterinary Hospital / Veterinary Directorate, and has been working in Central Veterinary Laboratory/ Veterinary Directorate. The ELISA diagnostic kits are selected for the detection of antibodies of Brucella abortus, Toxoplasmosis and Foot and Mouth disease (Multispecies). The result of the research is the presence of different levels of infection in the same herd 58.18% of Brucella abortus, 11.40% of Toxoplasmosis and 44.73 % of Foot and Mouth disease (Multispecies). The purpose of the study is to investigate the three diseases and their compatibility with the symptoms, although buffalo herds have not been previously vaccinated against the diseases, which proves the existence of different levels of infection in one herd and it adversely affect the development of livestock.
本研究旨在调查巴格达村水牛群的布鲁氏菌病、弓形虫病和口蹄疫。收集了114个样本(血清),包括22个小于6个月的小牛样本和92个3至7岁的雌性样本,这些样本由巴格达兽医医院/兽医局的工作人员收集,并一直在中央兽医实验室/兽医局工作。选择ELISA诊断试剂盒检测流产布鲁氏菌、弓形虫病和口蹄疫(多种)抗体。研究结果表明,同一畜群中存在不同程度的感染,其中流产布鲁氏菌占58.18%,弓形体病占11.40%,口蹄疫占44.73%(多种)。本研究的目的是调查这三种疾病及其与症状的相容性,尽管水牛群以前没有接种过这三种疾病的疫苗,但这证明在一个牛群中存在不同程度的感染,并对牲畜的发育产生不利影响。
{"title":"Investigation of Buffalo Herd’s Diseases-Brucellosis, Toxoplasmosis, Foot and Mouth Disease- in Some Villages of Baghdad","authors":"Dr. Nadia Jasim Sudani, Dr. Ameerah Hussein, Qader, Dr. Hudhaifa Abdul, Mahdi Hadi, Dr. Luma Youssef, Dr. Salma Talib, Dr. Ibtisam Jasim, Sodani Dr. Ahmed, Mounir, Dr. Jabbar Khalaf, Dr. Kalaman Majid, Dr. Ahmed Fadel, Dr. Saeed Ibrahim, Qusay, Dr. Adnan Ibrahim Salem, دمحأ, فلخ, .د رابج, نملك, .د, ميهاربأ, ناندع.د, .د ديعس","doi":"10.36326/kjvs/2021/v12i13224","DOIUrl":"https://doi.org/10.36326/kjvs/2021/v12i13224","url":null,"abstract":"This study is to investigate Brucellosis, Toxoplasmosis and Foot and Mouth disease of buffalo herds in Baghdad villages. 114 samples (serum) were collected, including 22 for calves less than 6 months and 92 samples of females aged between three to seven years, the samples were collected by staff of Baghdad Veterinary Hospital / Veterinary Directorate, and has been working in Central Veterinary Laboratory/ Veterinary Directorate. \u0000The ELISA diagnostic kits are selected for the detection of antibodies of Brucella abortus, Toxoplasmosis and Foot and Mouth disease (Multispecies). \u0000The result of the research is the presence of different levels of infection in the same herd \u000058.18% of Brucella abortus, 11.40% of Toxoplasmosis and 44.73 % of Foot and Mouth disease (Multispecies). \u0000The purpose of the study is to investigate the three diseases and their compatibility with the symptoms, although buffalo herds have not been previously vaccinated against the diseases, which proves the existence of different levels of infection in one herd and it adversely affect the development of livestock.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83105789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation the sedative and analgesic effects of tramadol and chlorpromazine alone or as a combination in chicks 评价曲马多与氯丙嗪单独或联合应用对雏鸡的镇静镇痛作用
Pub Date : 2021-06-30 DOI: 10.36326/kjvs/2021/v12i13221
Manahel Allawi Abdulla Aljbori, Rawnaq Faris Abdulqader Alshalchi, Ghada Abdulmunem Faris
The goal of this study was to assess the pain-relieving action of tramadol alone or when administered with chlorpromazine and screening for analgesic effects by using sedative non-analgesic doses of tramadol and chlorpromazine when injected together in chicks. the analgesic ED50 of tramadol was 0.8 mg/kg body weight ( intra muscular injection), and the sedative ED50 of chlorpromazine was 8.6 mg / kg of body weight (intraperitoneal injection). Based on Isopolographic analysis, the type of drug interaction between tramadol and chlorpromazine was determined when injected together in a ratio by 1: 1, 1: 0.5 and 0.5: 0.5 from the median effective dose(ED50 )of tramadol and the median effective dose of chlorpromazine was synergetic interaction. Thus conclude that combination of tramadol and chlorpromazine with sedative non-analgesic doses is ideal for a good analgesic effect of pain in chicks
本研究的目的是评估曲马多单独或与氯丙嗪联合使用时的镇痛作用,并通过曲马多和氯丙嗪同时注射时的镇静非镇痛剂量筛选镇痛效果。曲马多镇痛ED50为0.8 mg/kg体重(肌内注射),氯丙嗪镇静ED50为8.6 mg/kg体重(腹腔注射)。通过等极性分析,从曲马多的中位有效剂量(ED50)和氯丙嗪的中位有效剂量(ED50)出发,确定曲马多与氯丙嗪按1:1、1:1 .5和0.5 .5的比例同时注射时的药物相互作用类型。综上所述,曲马多与氯丙嗪在非镇痛镇静剂量下联合使用对雏鸡疼痛有较好的镇痛效果
{"title":"Evaluation the sedative and analgesic effects of tramadol and chlorpromazine alone or as a combination in chicks","authors":"Manahel Allawi Abdulla Aljbori, Rawnaq Faris Abdulqader Alshalchi, Ghada Abdulmunem Faris","doi":"10.36326/kjvs/2021/v12i13221","DOIUrl":"https://doi.org/10.36326/kjvs/2021/v12i13221","url":null,"abstract":"The goal of this study was to assess the pain-relieving action of tramadol alone or when administered with chlorpromazine and screening for analgesic effects by using sedative non-analgesic doses of tramadol and chlorpromazine when injected together in chicks. the analgesic ED50 of tramadol was 0.8 mg/kg body weight ( intra muscular injection), and the sedative ED50 of chlorpromazine was 8.6 mg / kg of body weight (intraperitoneal injection). Based on Isopolographic analysis, the type of drug interaction between tramadol and chlorpromazine was determined when injected together in a ratio by 1: 1, 1: 0.5 and 0.5: 0.5 from the median effective dose(ED50 )of tramadol and the median effective dose of chlorpromazine was synergetic interaction. Thus conclude that combination of tramadol and chlorpromazine with sedative non-analgesic doses is ideal for a good analgesic effect of pain in chicks","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81970386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Deferoxamine on Rat Fetal Bone Formation and on it is Certain Regulating Genes 去铁胺对大鼠胎骨形成及其调控基因的影响
Pub Date : 2021-06-30 DOI: 10.36326/kjvs/2021/v12i13220
A. E. Thanoon, A. S. Alchalabi
The aim of this study is to investigate the deferoxamine effect on rat fetal bone formation and on certain regulating genes expression that play a vital key role in bone formation. Sixty albino adult female rats three months old with average weight 170-200g were employed in this study. The rats were distributed randomly in to two groups. Control group (n=30) receiving 0.3ml ip physiological saline and deferoxamine methane intra peritoneal daily at a dose of 100 mg/kg throughout the pregnancy from the first day of pregnancy until last day of pregnancy. Skeleton samples and staining were done on sixty fetuses were chosen from each group at 20 days of pregnancy as well as liver samples from mothers and their fetuses for studying gene expression of Msx1 and Cx43. The results showed that many variations in certain bone formation and development markers were recorded as well as there was downregulation of studied genes. In conclusion, the study found that deferoxamine affect negatively on certain bone development markers and on gene expression of Msx1 and Cx43 represented as downregulation.
本研究旨在探讨去铁胺对大鼠胎儿骨形成的影响,以及对骨形成中起关键作用的调节基因表达的影响。本研究选用平均体重170 ~ 200g、3月龄的成年白化雌性大鼠60只。将大鼠随机分为两组。对照组(n=30)从妊娠第一天至妊娠最后一天,每天腹腔注射去铁胺甲烷和生理盐水0.3ml,剂量为100 mg/kg。在妊娠第20天,每组选取60例胎儿的骨骼样本和染色,同时选取母亲及其胎儿的肝脏样本,研究Msx1和Cx43的基因表达。结果显示,某些骨形成和发育标志物发生了许多变化,所研究的基因也出现了下调。综上所述,本研究发现去铁胺对某些骨发育标志物及Msx1和Cx43基因表达有负性影响,表现为下调。
{"title":"Effect of Deferoxamine on Rat Fetal Bone Formation and on it is Certain Regulating Genes","authors":"A. E. Thanoon, A. S. Alchalabi","doi":"10.36326/kjvs/2021/v12i13220","DOIUrl":"https://doi.org/10.36326/kjvs/2021/v12i13220","url":null,"abstract":"The aim of this study is to investigate the deferoxamine effect on rat fetal bone formation and on certain regulating genes expression that play a vital key role in bone formation. Sixty albino adult female rats three months old with average weight 170-200g were employed in this study. The rats were distributed randomly in to two groups. Control group (n=30) receiving 0.3ml ip physiological saline and deferoxamine methane intra peritoneal daily at a dose of 100 mg/kg throughout the pregnancy from the first day of pregnancy until last day of pregnancy. Skeleton samples and staining were done on sixty fetuses were chosen from each group at 20 days of pregnancy as well as liver samples from mothers and their fetuses for studying gene expression of Msx1 and Cx43. The results showed that many variations in certain bone formation and development markers were recorded as well as there was downregulation of studied genes. In conclusion, the study found that deferoxamine affect negatively on certain bone development markers and on gene expression of Msx1 and Cx43 represented as downregulation.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83802583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Kufa Journal For Veterinary Medical Sciences
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1