Ahmed Abdul Hadi Mohsen, Hiba Sadiq Mohammed Hassan, Ahmed Mohamad Mechi, A. Nasrawi
Celiac disease is a multisystem disorder in children and adults; it is considered as one of the most important malabsorption syndromes related to an auto-immune mediated response to gluten-containing food in a genetically predisposed patient. The most common involved system is the Gastrointestinal tract. Association with other autoimmune diseases such as thyroid disease and diabetes mellitus type 1 is well known but autoimmune mediated hemolytic anemia that responded to a gluten-free diet was interesting to be found. A six years old male previously healthy child, presented with pallor and reduced activity, dark-colored urine, with clinical and laboratory features of hemolytic anemia, and multiple blood transfusions within a year of medical care-seeking to finally diagnosed with celiac disease and responded to a gluten-free diet of about 8 months now with no need of blood transfusion.
{"title":"Autoimmune Hemolytic Anemia as Presentation of Celiac Disease","authors":"Ahmed Abdul Hadi Mohsen, Hiba Sadiq Mohammed Hassan, Ahmed Mohamad Mechi, A. Nasrawi","doi":"10.36330/kmj.v18i2.3660","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.3660","url":null,"abstract":"Celiac disease is a multisystem disorder in children and adults; it is considered as one of the most important malabsorption syndromes related to an auto-immune mediated response to gluten-containing food in a genetically predisposed patient. The most common involved system is the Gastrointestinal tract. Association with other autoimmune diseases such as thyroid disease and diabetes mellitus type 1 is well known but autoimmune mediated hemolytic anemia that responded to a gluten-free diet was interesting to be found.\u0000A six years old male previously healthy child, presented with pallor and reduced activity, dark-colored urine, with clinical and laboratory features of hemolytic anemia, and multiple blood transfusions within a year of medical care-seeking to finally diagnosed with celiac disease and responded to a gluten-free diet of about 8 months now with no need of blood transfusion.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81438583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Physicians are always exposed to work-related risk factors that may result in many diseases. Many studies showed the high prevalence of LBP (LBP) among physicians in comparison to other musculoskeletal diseases. The present study aims to estimate the prevalence of LBP among physicians in Erbil city and to detect its related risk factors. Subjects and methods: a cross-sectional study was conducted among physicians from all specialties inside two tertiary hospitals from Feb 1st, 2021 to Aug 2021. A questionnaire prepared by the investigator was used for data collection. The severity of LBP was assessed by a visual analog scale: from 1-3 was considered mild pain, 4-6 was moderate, and 7-10 was severe pain. Results: It has been found that the mean BMI difference between the two groups, with and without LBP, was (27.84 ± 1.18Vs 25.46 ± 1.28) with a significant p= 0.003. The proportion with irregular sleep was (83.07% Vs 22.53%) among both groups respectively with a statistically significant p=0.032. The overall prevalence rate of LBP among physicians was 78.6%; 71.4% were males and only 28.6% were females with a significant p=0.001. The result of logistic regression for the overweight, obese, regular sleeping, and lifting heavy objects, OR with 95% confidence intervals, were; 3.40 (0.37-30.6), 2.36(0.5-10.3), 1.57(0.99-2.48), and 2.63(1.63-4.25) respectively. Conclusion: the prevalence of LBP among physicians appears to be high and constitutes a major health concern. The BMI, lifting heavy objects, and sleep patterns were good predictors of LBP among physicians.
{"title":"Prevalence of LBP among physicians in Erbil city","authors":"Aram Abdalla Mala, Shwan Kader Media","doi":"10.36330/kmj.v18i2.3688","DOIUrl":"https://doi.org/10.36330/kmj.v18i2.3688","url":null,"abstract":"Background: Physicians are always exposed to work-related risk factors that may result in many diseases. Many studies showed the high prevalence of LBP (LBP) among physicians in comparison to other musculoskeletal diseases. The present study aims to estimate the prevalence of LBP among physicians in Erbil city and to detect its related risk factors.\u0000Subjects and methods: a cross-sectional study was conducted among physicians from all specialties inside two tertiary hospitals from Feb 1st, 2021 to Aug 2021. A questionnaire prepared by the investigator was used for data collection. The severity of LBP was assessed by a visual analog scale: from 1-3 was considered mild pain, 4-6 was moderate, and 7-10 was severe pain.\u0000Results: It has been found that the mean BMI difference between the two groups, with and without LBP, was (27.84 ± 1.18Vs 25.46 ± 1.28) with a significant p= 0.003. The proportion with irregular sleep was (83.07% Vs 22.53%) among both groups respectively with a statistically significant p=0.032. The overall prevalence rate of LBP among physicians was 78.6%; 71.4% were males and only 28.6% were females with a significant p=0.001. The result of logistic regression for the overweight, obese, regular sleeping, and lifting heavy objects, OR with 95% confidence intervals, were; 3.40 (0.37-30.6), 2.36(0.5-10.3), 1.57(0.99-2.48), and 2.63(1.63-4.25) respectively.\u0000Conclusion: the prevalence of LBP among physicians appears to be high and constitutes a major health concern. The BMI, lifting heavy objects, and sleep patterns were good predictors of LBP among physicians.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83897842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.36326/kjvs/2022/v13i13709
Nabeel M. N. Al-Sharafi, Saja Mazin Radhi Alobaidy
This study was designed to induction of testicular degeneration syndrome (TDS) in male rats by cadmium chloride and identified the best concentration of induction for this syndrome. The effective dose of cadmium chloride (CdCl₂) was determined by used fifteen males rats and where divided into three equal groups treated with CdCl₂ in a concentration (1, 2 and 3)mg/kg B.W. I.P. one /week for two weeks. Later the experimental animals was scarified and testis was took for measuring the antioxidant parameters via evaluated of glutathione GSH, malondialdehyde MDA, catalse, albumin, fructose concentrations and aminotransferase activity (ALT and AST). According to this result the lowest observed adverse effective dose (LOAEL) of cadmium chloride that induced testicular degeneration in male rats was found to be 1mg/kg B.W. I.p. one /week for two weeks.
{"title":"Induction of Testicular Degeneration syndrome via Cadmium Chloride in male Albino rats","authors":"Nabeel M. N. Al-Sharafi, Saja Mazin Radhi Alobaidy","doi":"10.36326/kjvs/2022/v13i13709","DOIUrl":"https://doi.org/10.36326/kjvs/2022/v13i13709","url":null,"abstract":"This study was designed to induction of testicular degeneration syndrome (TDS) in male rats by cadmium chloride and identified the best concentration of induction for this syndrome. \u0000The effective dose of cadmium chloride (CdCl₂) was determined by used fifteen males rats and where divided into three equal groups treated with CdCl₂ in a concentration (1, 2 and 3)mg/kg B.W. I.P. one /week for two weeks. Later the experimental animals was scarified and testis was took for measuring the antioxidant parameters via evaluated of glutathione GSH, malondialdehyde MDA, catalse, albumin, fructose concentrations and aminotransferase activity (ALT and AST). \u0000According to this result the lowest observed adverse effective dose (LOAEL) of cadmium chloride that induced testicular degeneration in male rats was found to be 1mg/kg B.W. I.p. one /week for two weeks.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88667678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.36326/kjvs/2022/v13i13673
Khairy Abdullah Dawood
In response to public health , it is necessary to write a review on COVID-19 disease as emerging zoonotic disease . Transmission of the new pathogen SARS-CoV-2 virus have several ways. These ways , spill – over or Evolutionary jump help virus to spread from one host to another with a rapid adaptation ( Epidemiological cycling ) . Covid-19 can transmitted from animals to humans (Zoonotic disease ) or from humans to animals ( Zooanthroponosis ) or from humans to humans ( Emerging Infectious disease ) or from animals to animals as infectious disease . On other hand some several wild animals considered as reservoir hosts such as bats , snakes , frogs , hedge-hoge , wild rats , marmots and rabbits ( Mohamed A . Mahdy , Waleed younis , Zamzam Ewaida 2020 ) . Since December 2019 when Covid-19 emerged in human from seafood market at Wuhan , Huanan city south China , rapidly transmitted all over the world as viral outbreak .
{"title":"A review on Covid-19 (Corona Virus Disease), Transmission and Pathological effects","authors":"Khairy Abdullah Dawood","doi":"10.36326/kjvs/2022/v13i13673","DOIUrl":"https://doi.org/10.36326/kjvs/2022/v13i13673","url":null,"abstract":"In response to public health , it is necessary to write a review on COVID-19 disease as emerging zoonotic disease . Transmission of the new pathogen SARS-CoV-2 virus have several ways. These ways , spill – over or Evolutionary jump help virus to spread from one host to another with a rapid adaptation ( Epidemiological cycling ) . \u0000Covid-19 can transmitted from animals to humans (Zoonotic disease ) or from humans to animals ( Zooanthroponosis ) or from humans to humans ( Emerging Infectious disease ) or from animals to animals as infectious disease . \u0000On other hand some several wild animals considered as reservoir hosts such as bats , snakes , frogs , hedge-hoge , wild rats , marmots and rabbits ( Mohamed A . Mahdy , Waleed younis , Zamzam Ewaida 2020 ) . \u0000Since December 2019 when Covid-19 emerged in human from seafood market at Wuhan , Huanan city south China , rapidly transmitted all over the world as viral outbreak . \u0000 \u0000 \u0000 ","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73141012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.36326/kjvs/2022/v13i13218
Ashwaq Miahy, Ban Abdulhussain Saleh
Testing of blood biochemical parameters is a pre-symptomatic diagnostic appliance to determine the nutritional status of any dairy herd and other disorders such as productive and reproductive, these parameters are influenced by both intrinsic and extrinsic factors like breed, age, sex, lactation, pregnancy, health and nutrition status of the cows in dairy herd. The present study was undertaken to estimate the selected biochemical nutritional status of dairy cows in Thiqar province in relation to reproductive status as estrus, pregnancy and lactation, this study was conducted on 40 local healthy cows in the teaching veterinary hospital of Thiqar province, they were divided into four groups estrus, pregnant between 2-8 months, lactating (calving) for 1 to 2 months and heifer (dry) cows of 10 animal for each group, cows were grouped into the previous four categories on the basis of reproductive history.
{"title":"Comparative Estimation of Serum Biochemical During Estrus, Pregnancy and Calving Periods for Dairy Cows in Thiqar Province.","authors":"Ashwaq Miahy, Ban Abdulhussain Saleh","doi":"10.36326/kjvs/2022/v13i13218","DOIUrl":"https://doi.org/10.36326/kjvs/2022/v13i13218","url":null,"abstract":"Testing of blood biochemical parameters is a pre-symptomatic diagnostic appliance to determine the nutritional status of any dairy herd and other disorders such as productive and reproductive, these parameters are influenced by both intrinsic and extrinsic factors like breed, age, sex, lactation, pregnancy, health and nutrition status of the cows in dairy herd. The present study was undertaken to estimate the selected biochemical nutritional status of dairy cows in Thiqar province in relation to reproductive status as estrus, pregnancy and lactation, this study was conducted on 40 local healthy cows in the teaching veterinary hospital of Thiqar province, they were divided into four groups estrus, pregnant between 2-8 months, lactating (calving) for 1 to 2 months and heifer (dry) cows of 10 animal for each group, cows were grouped into the previous four categories on the basis of reproductive history.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83167537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.36326/kjvs/2022/v13i13277
O. Fahad
The current study was conducted to estimate the Zinc(Zn) levels in serum of (190) Awassi sheep (males) in Fallujah city/ Iraq. The animals were examined clinically and serum samples were examined by atomic absorption spectrophotometer (AAS) to detect the Zn concentration, the results showed decrease in zinc level in addition to significant (P≤0.05) difference between among the control group 0.67±0.42 ppm and affected which include Al-bushegel group0.21±0.42 ppm, Al-falaahat group0.18±0.12 ppm and Al-bualwaan group0.13±0.27 ppm. Also, RBCs reduced in Al-bushegel group6.88±0.51* 106/ul, Al-falaahat group7.03 ± 0.26* 106/ul, and Al-bualwaan group6.37 ± 0.84* 106/ul, thus Hb declined in Al-bushegel group 7.13±0.22g/dl, Al-falaahat group 7.27±0.32g/dl, and Al-bualwaan group 6.82 ± 0.43g/dl in the whole blood samples. PCV was also significant (P≤0.05) reduced in Al-bushegel group 21.41±0.53%, Al-falaahat group 21.75 ± 0.48%, and Al-bualwaan group 20.21 ± 0.15%. On the other hand, the results showed an insignificant difference in MCV among Al-bushegel group 31.1± 0.12fL, Al-falaahat group 30.9± 0.92fL, and Al-bualwaan group 31.7± 0.35fL, but there's no substantial difference in MCHC between Al-bushegel group 33.1±0.21g/dl, Al-falaahat group 33.4±0.54g/dl, and Al-bualwaan group 32.7±0.40g/dl. When compared to control 35.70±2.42 (U/L), there was no significant difference in ALT activity in Al-bushegel group l 31.16 ± 0.19 (U/L), Al-falaahat group 30.60 ± 0.84 (U/L), and Al-bualwaan group 28.22 ± 1.13 (U/L). Furthermore, as compared to control 86.20±18.79 (U/L), AST activity was substantially higher in Al-bushegel group 46.38 ± 1.32 (U/L), Al-falaahat group 42.11 ± 0.82 (U/L), and Albualwaan group 39.48 ± 1.75 (U/L). In this investigation, serum urea levels were 48.09 ± 0.05, 43.00 ± 0.47 and 51.50 ± 0.89 (mg/dl) in Al-bushegel, Al-falaahat, and Al-bualwaan groups respectively, compared to control levels of 22.35±0.11 mg/dl. In comparison to control 0.71±0.04 (mg/dl), serum creatinine levels increased significantly in Al-bushegel group 1.09 ± 0.01 (mg/dl), Al-falaahat group 1.12 ± 0.06 (mg/dl), and Al-bualwaan group 1.14 ± 0.03 (mg/dl). The affected animal group's heart and respiration rates were significantly (P≤0.05) higher than those of the control group. In conclusion, it was a considerable difference in Zinc concentrations, haematological, and biochemical characteristics among sheep studied in Fallujah, Iraq
{"title":"Hematological and Biochemical Study of Zinc deficiency in Sheep in Fallujah city /Iraq.","authors":"O. Fahad","doi":"10.36326/kjvs/2022/v13i13277","DOIUrl":"https://doi.org/10.36326/kjvs/2022/v13i13277","url":null,"abstract":"The current study was conducted to estimate the Zinc(Zn) levels in serum of (190) Awassi sheep (males) in Fallujah city/ Iraq. The animals were examined clinically and serum samples were examined by atomic absorption spectrophotometer (AAS) to detect the Zn concentration, the results showed decrease in zinc level in addition to significant (P≤0.05) difference between among the control group 0.67±0.42 ppm and affected which include Al-bushegel group0.21±0.42 ppm, Al-falaahat group0.18±0.12 ppm and Al-bualwaan group0.13±0.27 ppm. Also, RBCs reduced in Al-bushegel group6.88±0.51* 106/ul, Al-falaahat group7.03 ± 0.26* 106/ul, and Al-bualwaan group6.37 ± 0.84* 106/ul, thus Hb declined in Al-bushegel group 7.13±0.22g/dl, Al-falaahat group 7.27±0.32g/dl, and Al-bualwaan group 6.82 ± 0.43g/dl in the whole blood samples. PCV was also significant (P≤0.05) reduced in Al-bushegel group 21.41±0.53%, Al-falaahat group 21.75 ± 0.48%, and Al-bualwaan group 20.21 ± 0.15%. On the other hand, the results showed an insignificant difference in MCV among Al-bushegel group 31.1± 0.12fL, Al-falaahat group 30.9± 0.92fL, and Al-bualwaan group 31.7± 0.35fL, but there's no substantial difference in MCHC between Al-bushegel group 33.1±0.21g/dl, Al-falaahat group 33.4±0.54g/dl, and Al-bualwaan group 32.7±0.40g/dl. When compared to control 35.70±2.42 (U/L), there was no significant difference in ALT activity in Al-bushegel group l 31.16 ± 0.19 (U/L), Al-falaahat group 30.60 ± 0.84 (U/L), and Al-bualwaan group 28.22 ± 1.13 (U/L). Furthermore, as compared to control 86.20±18.79 (U/L), AST activity was substantially higher in Al-bushegel group 46.38 ± 1.32 (U/L), Al-falaahat group 42.11 ± 0.82 (U/L), and Albualwaan group 39.48 ± 1.75 (U/L). In this investigation, serum urea levels were 48.09 ± 0.05, 43.00 ± 0.47 and 51.50 ± 0.89 (mg/dl) in Al-bushegel, Al-falaahat, and Al-bualwaan groups respectively, compared to control levels of 22.35±0.11 mg/dl. In comparison to control 0.71±0.04 (mg/dl), serum creatinine levels increased significantly in Al-bushegel group 1.09 ± 0.01 (mg/dl), Al-falaahat group 1.12 ± 0.06 (mg/dl), and Al-bualwaan group 1.14 ± 0.03 (mg/dl). The affected animal group's heart and respiration rates were significantly (P≤0.05) higher than those of the control group. In conclusion, it was a considerable difference in Zinc concentrations, haematological, and biochemical characteristics among sheep studied in Fallujah, Iraq","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76926290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.36326/kjvs/2022/v13i13351
H. Alaa, Kifah Fadhil Hassoon
Wounds infection is pathogen-infected to the point where it triggers a local and systemic reaction in the host. Multiple pathogens typically colonize wounds, and Pseudomonas aeruginosa has a higher prevalence in wound infection. This study tried to assess the immune response by measuring the level of complement fragment C5a in the serum of rats that induced wound infected with Pseudomonas aeruginosa. The animal was divided into three groups ( infected wound , wound without infection, and healthy control ) and the procedure was performed by inducing 10 mm excisional wound on the dorsal region of rats and after 24h from inducing wound contaminated the wound region in the infected group only with bacterial suspension that contains 2.5 ×106 CFU of P. aeruginosa. Then at specific determined time points (24hrs, 48hrs, 72hrs) after infection blood samples and skin biopsy samples were collected. By using ELISA kitt sandwich methods we found that C5a is highly elevated in the infected group in comparison with other animal groups. And the histological section showed no signs of inflammation during 24hrs while necrosis of the dermis layer was observed after 48hrs and 72hrs.
{"title":"The Levels of Complement C5a in Wound Infected with Pseudomonas aeruginosa in Albino Rat","authors":"H. Alaa, Kifah Fadhil Hassoon","doi":"10.36326/kjvs/2022/v13i13351","DOIUrl":"https://doi.org/10.36326/kjvs/2022/v13i13351","url":null,"abstract":"Wounds infection is pathogen-infected to the point where it triggers a local and systemic reaction in the host. Multiple pathogens typically colonize wounds, and Pseudomonas aeruginosa has a higher prevalence in wound infection. This study tried to assess the immune response by measuring the level of complement fragment C5a in the serum of rats that induced wound infected with Pseudomonas aeruginosa. The animal was divided into three groups ( infected wound , wound without infection, and healthy control ) and the procedure was performed by inducing 10 mm excisional wound on the dorsal region of rats and after 24h from inducing wound contaminated the wound region in the infected group only with bacterial suspension that contains 2.5 ×106 CFU of P. aeruginosa. Then at specific determined time points (24hrs, 48hrs, 72hrs) after infection blood samples and skin biopsy samples were collected. By using ELISA kitt sandwich methods we found that C5a is highly elevated in the infected group in comparison with other animal groups. And the histological section showed no signs of inflammation during 24hrs while necrosis of the dermis layer was observed after 48hrs and 72hrs.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88330729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: This study evaluated the anticancer effects of gold nanoparticles (Au- NPs) generated by reducing hydrated gold metal ions in the presence of aqueous pomegranate peel extract. Aim of study: To test the possibility that Au-NPs generated from the pomegranate aqueous extract could be employed as an anti-cancer therapy. Materials and methods: The study aimed to evaluate Photodynamic therapy (PDT) using a laser at a wavelength of 532 nm with green gold particles as a photosensitizer in in-vivo experiment. Gold nanoparticles (Au-NPs) were produced by reducing hydrated gold metal ions in the presence of aqueous pomegranate peel extract. Using UV-visible spectroscopy, the absorption peak of the gold particles was found near 550- 592 nm. All diffraction peaks for 2θ at = 37.8227º at 43.7014º, 63.8103º and 77.1540º correspond to the (111), (200), (220), and (311) levels, respectively by X-ray diffraction(XRD) analysis, imaging confirmed Au-NP by Transmission electron microscopy (TEM), the nanoparticle size ranged between 19.96 ± 0.784 nm. Forty Mature Swiss females weighing 20–25 g and aged 6–8 weeks were used, the animals were placed in well-ventilated rooms. Results: The best exposure time to eradicate the tumor is with a duration of exposure of 30 minutes using the diode laser, as histological investigations indicated the development of anti-immunity with the same exposure period.
{"title":"Evaluating the Anti-Cancer Effect of Pomegranate Aqueous Extract of Gold Nanoparticles by Using Photodynamic Laser on Laboratory Mice.","authors":"Entidhar Jasim Khamees Altae","doi":"10.36330/kmj.v18i1.3332","DOIUrl":"https://doi.org/10.36330/kmj.v18i1.3332","url":null,"abstract":"Background: This study evaluated the anticancer effects of gold nanoparticles (Au- NPs) generated by reducing hydrated gold metal ions in the presence of aqueous pomegranate peel extract.\u0000Aim of study: To test the possibility that Au-NPs generated from the pomegranate aqueous extract could be employed as an anti-cancer therapy.\u0000Materials and methods: The study aimed to evaluate Photodynamic therapy (PDT) using a laser at a wavelength of 532 nm with green gold particles as a photosensitizer in in-vivo experiment. Gold nanoparticles (Au-NPs) were produced by reducing hydrated gold metal ions in the presence of aqueous pomegranate peel extract. Using UV-visible spectroscopy, the absorption peak of the gold particles was found near 550- 592 nm. All diffraction peaks for 2θ at = 37.8227º at 43.7014º, 63.8103º and 77.1540º correspond to the (111), (200), (220), and (311) levels, respectively by X-ray diffraction(XRD) analysis, imaging confirmed Au-NP by Transmission electron microscopy (TEM), the nanoparticle size ranged between 19.96 ± 0.784 nm. Forty Mature Swiss females weighing 20–25 g and aged 6–8 weeks were used, the animals were placed in well-ventilated rooms.\u0000Results: The best exposure time to eradicate the tumor is with a duration of exposure of 30 minutes using the diode laser, as histological investigations indicated the development of anti-immunity with the same exposure period.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75046457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atrioventricular septal defect is a spectrum of congenital heart defects that can be classified as either complete or partial with the complete form being the most common and usually present in the neonatal period with congestive heart failure. However, partial defects can remain asymptomatic and present later in adulthood with variable degrees of heart failure. The case under investigation is a middle aged female with a 2-year history of worsening dyspnea and recurrent chest infections due to undiagnosed partial atrioventricular septal defects. As a conclusion, it is important to establish a screening program to detect the asymptomatic cases early and prevent delay consequences.
{"title":"Late Presentation of Partial Atrioventricular Septal Defect: A Case Report","authors":"G. Kareem, W. Mahbuba","doi":"10.36330/kmj.v18i1.3474","DOIUrl":"https://doi.org/10.36330/kmj.v18i1.3474","url":null,"abstract":"Atrioventricular septal defect is a spectrum of congenital heart defects that can be classified as either complete or partial with the complete form being the most common and usually present in the neonatal period with congestive heart failure. However, partial defects can remain asymptomatic and present later in adulthood with variable degrees of heart failure. The case under investigation is a middle aged female with a 2-year history of worsening dyspnea and recurrent chest infections due to undiagnosed partial atrioventricular septal defects. As a conclusion, it is important to establish a screening program to detect the asymptomatic cases early and prevent delay consequences.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75610432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Polycystic ovarian syndrome is a common public health issue around the world. Insulin resistance and glucose intolerance play important role in the etiology of polycystic ovarian syndrome and the serum mannose is incorporated in metabolism of glucose. Aim of study: Determination of the association between serum mannose level and polycystic ovarian syndrome. Patients and Methods: A case control study enrolled eighty eight women were divided as forty four women with polycystic ovarian syndrome and forty four women without polycystic ovarian syndrome presented to outpatient clinic at Fertility Center/Al Sader Medical City and outpatient clinic of Al- Zahraa Teaching Hospital in Najaf city-Iraq during the period from 1st of February till 31st of December, 2020. Results: The mean Serum Mannose level of women with polycystic ovarian syndrome 7.37 was significantly higher than mean serum mannose of controls 1.32 (p<0.001). Cutoff serum mannose level of 1.98 had acceptable validity results (90.9% sensitivity, 90.9% specificity, 94% PPV, 90.5% NPV and 90% accuracy). The means of serum level testosterone and luteinizing hormones were significantly higher among women with polycystic ovarian syndrome, while mean follicular stimulating hormone level was significantly lower among women with polycystic ovarian syndrome. Conclusions: The serum mannose level is significantly increased in women with polycystic ovarian syndrome which may indicate its possible role in the pathophysiology of polycystic ovarian syndrome.
{"title":"Serum Mannose Level and Its Association in Women with Polycystic Ovarian Syndrome: a Case Control Study of Al-Najaf City / 2020","authors":"Basima Shamkhi Al Ghazali, Sara Monther","doi":"10.36330/kmj.v18i1.3273","DOIUrl":"https://doi.org/10.36330/kmj.v18i1.3273","url":null,"abstract":"Background: Polycystic ovarian syndrome is a common public health issue around the world. Insulin resistance and glucose intolerance play important role in the etiology of polycystic ovarian syndrome and the serum mannose is incorporated in metabolism of glucose.\u0000Aim of study: Determination of the association between serum mannose level and polycystic ovarian syndrome.\u0000Patients and Methods: A case control study enrolled eighty eight women were divided as forty four women with polycystic ovarian syndrome and forty four women without polycystic ovarian syndrome presented to outpatient clinic at Fertility Center/Al Sader Medical City and outpatient clinic of Al- Zahraa Teaching Hospital in Najaf city-Iraq during the period from 1st of February till 31st of December, 2020.\u0000Results: The mean Serum Mannose level of women with polycystic ovarian syndrome 7.37 was significantly higher than mean serum mannose of controls 1.32 (p<0.001). Cutoff serum mannose level of 1.98 had acceptable validity results (90.9% sensitivity, 90.9% specificity, 94% PPV, 90.5% NPV and 90% accuracy). The means of serum level testosterone and luteinizing hormones were significantly higher among women with polycystic ovarian syndrome, while mean follicular stimulating hormone level was significantly lower among women with polycystic ovarian syndrome.\u0000Conclusions: The serum mannose level is significantly increased in women with polycystic ovarian syndrome which may indicate its possible role in the pathophysiology of polycystic ovarian syndrome.","PeriodicalId":17869,"journal":{"name":"Kufa Journal For Veterinary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76526863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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